Hub : Genes

ENSRNOG00000067659

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000067659 0.13 0.07 6.9e-06 0.12 0.07 0.11 0.02 7.3e-07 1.3e-04 2.0e-06 1.8e-02
2 BLA mRNA stability ENSRNOG00000067659 0.25 0.14 3.2e-05 0.07 0.04 0.06 0 8.0e-05 5.1e-03 5.9e-04 1.7e-01
3 Brain gene expression ENSRNOG00000067659 0.09 0.06 1.1e-07 0.07 0.08 0.07 0.07 2.3e-07 1.1e-07 4.2e-07 3.9e-07
4 Brain mRNA stability ENSRNOG00000067659 0.04 0.03 3.0e-03 0.03 0.03 0.03 0.04 2.1e-03 5.1e-04 4.4e-04 2.5e-04
5 LHb gene expression ENSRNOG00000067659 0.19 0.11 5.5e-03 0.1 -0 0.04 -0 2.4e-03 4.4e-01 3.4e-02 3.3e-01
6 Liver gene expression ENSRNOG00000067659 0.02 0.01 6.0e-03 0.01 0.02 0.01 0.01 4.4e-02 3.9e-03 1.6e-02 1.2e-02
7 NAcc gene expression ENSRNOG00000067659 0.14 0.08 5.1e-05 0.03 -0 0.06 -0 2.9e-03 3.9e-01 2.5e-05 6.0e-01
8 NAcc mRNA stability ENSRNOG00000067659 0.05 0.04 4.4e-03 0.03 0.03 0.03 -0 1.6e-03 2.9e-03 2.9e-03 6.0e-01
9 PL gene expression ENSRNOG00000067659 0.12 0.07 1.4e-08 0.13 0.11 0.13 0.12 6.3e-10 6.2e-09 4.8e-10 9.8e-10
10 PL mRNA stability ENSRNOG00000067659 0.06 0.04 6.2e-05 0.07 0.05 0.06 0.06 3.6e-06 1.8e-04 2.4e-05 1.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.51.62.5-1.3-1.6-0.8-1.3-1.3-0.4-1.2-1.5-1.1-1.6
BMI without tail4.69.612.6-3.1-3.5-1.9-3.2-3.5-1.3-3.5-3.4-3.2-3.5
Body weight5.322.625.5-4.9-5.0-4.7-4.9-4.7-4.3-4.2-4.9-4.7-5.0
Epididymis fat weight1.63.74.7-2.0-1.9-1.6-2.1-2.0-1.3-2.1-2.2-2.0-1.9
Glucose3.35.06.32.42.42.12.32.51.61.72.42.42.4
Heart weight0.50.71.5-1.0-0.9-0.4-0.9-0.8-0.5-1.2-0.9-0.8-0.9
Left kidney weight0.41.24.1-0.9-0.7-2.0-0.9-0.5-2.00.3-0.7-0.7-0.7
Right kidney weight0.41.13.0-1.0-0.8-1.7-1.0-0.4-1.60.3-0.9-0.5-0.8
Tail length7.422.524.9-4.8-4.9-4.2-4.9-4.9-4.0-4.8-4.9-5.0-4.9
Length with tail4.416.120.5-4.0-3.9-4.5-4.1-3.8-4.5-3.3-3.9-4.0-3.9
Length without tail0.30.73.3-0.4-0.1-1.6-0.30.2-1.80.8-0.2-0.1-0.1
Liver weight, left0.10.20.70.30.3-0.60.20.3-0.80.80.40.20.3
Liver weight, right3.45.68.0-2.4-2.3-2.7-2.4-2.2-2.8-1.6-2.3-2.3-2.3
Parametrial fat weight2.14.27.1-2.1-2.0-1.6-2.1-2.0-1.7-2.7-2.0-2.1-2.0
Retroperitoneal fat weight6.822.624.7-4.9-4.9-4.2-4.9-4.9-3.8-5.0-4.9-4.9-4.9
Intraocular pressure0.50.61.6-1.0-0.80.1-1.0-0.50.2-1.3-1.0-0.5-0.8
Extensor digitorum longus weight0.10.31.5-0.4-0.30.8-0.2-0.31.2-0.7-0.3-0.1-0.3
Soleus weight1.95.610.5-2.4-2.3-1.4-2.5-2.4-1.7-3.2-2.4-2.5-2.3
Tibialis anterior weight0.00.10.40.10.20.70.20.20.6-0.30.10.20.2
Tibia length10.930.850.7-5.2-5.3-7.1-5.6-5.3-6.9-2.9-5.3-5.6-5.3
Number of licking bursts0.20.30.4-0.4-0.5-0.6-0.6-0.6-0.5-0.5-0.5-0.6-0.5
Food consumed during 24 hour testing period1.11.42.1-1.1-1.2-1.0-1.2-1.3-0.7-1.4-1.2-1.3-1.2
Times rat made contact with spout1.82.05.7-1.2-1.3-0.8-1.4-1.5-1.1-2.4-1.3-1.6-1.3
Mean time between licks in bursts1.21.72.41.31.41.11.31.51.11.21.41.41.4
Mean num. licks in bursts0.30.31.7-0.5-0.40.1-0.4-0.5-0.0-1.3-0.4-0.5-0.4
Std. dev. time between licks in bursts0.81.03.0-1.0-1.0-0.3-1.0-0.90.1-1.7-1.0-1.0-1.0
Water consumed over 24 hours0.00.00.1-0.00.00.0-0.0-0.1-0.2-0.30.0-0.10.0
Indifference point 0 sec0.50.82.6-0.8-1.00.3-0.7-0.70.2-1.6-0.8-0.7-1.0
Indifference point AUC0.10.10.4-0.3-0.30.1-0.1-0.00.1-0.6-0.20.0-0.3
Indifference point function ln k1.21.72.31.31.31.51.31.11.51.21.21.21.3
Indifference point function log k1.21.72.31.31.31.51.31.11.51.21.21.21.3
Delay discounting total patch changes 0 sec0.50.82.5-0.9-1.10.4-0.7-0.70.5-1.6-0.8-0.6-1.1
Delay discounting total patch changes 12 sec0.50.73.1-0.9-0.90.4-0.7-0.20.3-1.8-0.7-0.2-0.9
Delay discounting total patch changes 18 sec0.20.21.0-0.5-0.40.6-0.10.01.0-0.6-0.30.2-0.4
Delay discounting total patch changes 24 sec1.82.23.1-1.5-1.8-1.1-1.5-1.4-0.9-1.8-1.5-1.4-1.8
Delay discounting total patch changes 6 sec1.01.55.5-1.3-1.2-0.1-1.2-1.0-0.5-2.3-1.1-1.0-1.2
Delay discounting time to switch 0 sec0.91.42.61.11.30.61.21.30.51.61.11.21.3
Delay discounting water rate 0 sec4.26.79.1-2.7-2.8-1.7-2.8-2.7-1.4-3.0-2.7-2.7-2.8
Delay discounting water rate 12 sec0.20.40.9-0.3-0.60.4-0.4-0.80.7-0.9-0.4-0.6-0.6
Delay discounting water rate 18 sec1.52.03.9-1.3-1.5-0.5-1.4-1.7-0.3-2.0-1.5-1.5-1.5
Delay discounting water rate 24 sec3.54.88.9-2.5-2.4-0.8-2.2-2.4-0.2-3.0-2.4-2.1-2.4
Delay discounting water rate 6 sec0.20.30.7-0.3-0.6-0.1-0.5-0.80.1-0.5-0.5-0.6-0.6
Locomotor activity0.50.81.50.90.70.81.00.70.81.21.00.90.7
Locomotor testing distance0.30.51.10.70.40.60.80.40.81.00.70.60.4
Locomotor testing rearing0.10.10.3-0.4-0.60.2-0.2-0.40.6-0.1-0.3-0.2-0.6
Light reinforcement 11.73.25.2-1.8-2.0-0.7-1.7-2.1-0.6-2.3-1.9-1.9-2.0
Light reinforcement 22.63.54.7-1.9-1.8-1.6-1.8-2.2-1.6-1.9-1.8-2.1-1.8
Reaction time number correct0.50.72.0-0.7-0.80.6-0.6-0.91.1-1.4-0.8-0.6-0.8
Reaction time mean minus median0.10.20.30.40.50.00.50.4-0.20.40.50.30.5
Reaction time mean minus median AUC0.20.30.9-0.5-0.4-0.9-0.4-0.3-1.0-0.2-0.3-0.4-0.4
Reaction time num false alarms0.20.30.60.40.50.60.40.80.70.40.40.70.5
Reaction time num false alarms AUC0.50.71.20.70.70.90.71.11.00.60.71.00.7
Reaction time trials correct on left0.50.72.0-0.7-0.80.6-0.6-0.91.1-1.4-0.8-0.6-0.8
Reaction time trials on left0.50.82.0-0.7-0.90.5-0.6-0.91.1-1.4-0.8-0.6-0.9
Reaction time mean0.10.10.3-0.5-0.4-0.4-0.2-0.5-0.2-0.3-0.4-0.4-0.4
Reaction time mean AUC0.10.20.3-0.5-0.4-0.3-0.2-0.5-0.1-0.4-0.4-0.4-0.4
Median of all reaction times0.10.20.4-0.6-0.5-0.4-0.3-0.5-0.1-0.3-0.6-0.4-0.5
Reaction time omissions0.30.40.8-0.7-0.5-0.9-0.5-0.7-0.7-0.1-0.6-0.6-0.5
Reaction time false alarm rate0.81.22.21.01.10.61.01.50.41.31.01.21.1
Reaction time premature initiation rate1.62.23.61.21.41.91.41.61.81.01.31.61.4
Reaction time premature initiations1.01.45.10.70.72.00.90.92.30.00.71.00.7
Std. dev. reaction times0.40.50.70.60.70.60.80.80.70.70.70.80.7
Reaction time trials completed0.50.82.0-0.7-0.90.5-0.6-0.91.1-1.4-0.8-0.6-0.9
Reaction time trials AUC0.60.92.4-0.8-0.90.5-0.7-1.01.1-1.6-0.9-0.7-0.9
Social response proportion0.10.10.4-0.00.00.10.00.40.50.6-0.00.30.0
Social responses0.20.30.5-0.6-0.7-0.5-0.6-0.2-0.1-0.1-0.6-0.3-0.7
Social time0.00.10.40.10.10.4-0.10.20.60.00.00.20.1
Conditioned locomotion4.75.68.4-2.6-2.5-1.7-2.4-2.4-1.4-2.9-2.5-2.3-2.5
Cocaine response after cond. corrected0.10.10.20.40.40.20.40.30.20.30.40.40.4
Cocaine response after cond. not corrected0.80.91.11.01.00.61.00.90.60.91.01.01.0
Cocaine response before conditioning0.91.11.51.11.10.81.11.10.71.21.11.11.1
Saline control response3.14.24.5-2.1-2.0-2.0-2.0-2.1-2.0-2.0-2.0-2.1-2.0
Condit. Reinf. active minus inactive responses1.41.72.8-1.4-1.3-1.7-1.3-1.3-1.3-0.4-1.3-1.3-1.3
Condit. Reinf. active-inactive response ratio3.13.23.7-1.8-1.8-1.9-1.9-1.7-1.9-1.5-1.8-1.8-1.8
Condit. Reinf. active responses0.30.40.6-0.8-0.7-0.6-0.7-0.6-0.20.0-0.7-0.6-0.7
Condit. Reinf. inactive responses0.70.81.80.60.81.10.90.81.31.00.80.90.8
Condit. Reinf. lever presses0.20.30.4-0.7-0.70.1-0.6-0.60.5-0.6-0.7-0.5-0.7
Condit. Reinf. lever reinforcers received0.20.30.6-0.8-0.7-0.4-0.6-0.60.20.1-0.7-0.5-0.7
Pavlov. Cond. lever latency0.91.22.81.21.20.11.11.2-0.21.71.21.11.2
Pavlov. Cond. magazine entry latency1.21.44.10.81.01.61.11.02.00.71.01.21.0
Pavlov. Cond. change in total contacts0.20.32.00.10.21.00.20.21.4-0.00.20.30.2
Pavlov. Cond. index score0.20.21.5-0.2-0.10.8-0.1-0.11.2-0.5-0.10.1-0.1
Pavlov. Cond. latency score0.20.21.1-0.3-0.20.6-0.2-0.21.1-0.5-0.2-0.1-0.2
Pavlov. Cond. lever contacts1.21.73.2-1.4-1.4-0.4-1.4-1.40.0-1.8-1.4-1.3-1.4
Pavlov. Cond. magazine entry number0.91.14.0-0.6-0.8-1.6-0.9-0.8-2.0-0.4-0.8-1.0-0.8
Pavlov. Cond. intertrial magazine entries1.92.53.0-1.5-1.6-1.7-1.6-1.6-1.6-1.0-1.6-1.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.20.32.0-0.00.11.00.10.11.4-0.30.10.30.1
Pavlov. Cond. response bias0.30.41.0-0.6-0.50.4-0.5-0.50.8-1.0-0.5-0.4-0.5
Conditioned reinforcement - actives0.30.30.8-0.4-0.6-0.1-0.4-0.9-0.2-0.7-0.5-0.6-0.6
Conditioned reinforcement - inactives2.12.43.6-1.4-1.7-1.3-1.6-1.4-1.4-1.9-1.5-1.5-1.7
Conditioned locomotion1.01.23.3-0.8-1.1-0.3-1.0-1.2-0.7-1.8-1.0-1.0-1.1
Intermittent access intake day 1-15 change0.10.10.4-0.2-0.3-0.6-0.3-0.3-0.50.3-0.3-0.3-0.3
Intermittent access intake escalation0.20.20.4-0.4-0.5-0.6-0.4-0.5-0.50.1-0.5-0.4-0.5
Intermittent access intake escalation 20.50.51.1-0.5-0.7-1.0-0.6-0.7-1.1-0.1-0.7-0.6-0.7
Intermitt. access day 1 inactive lever presses2.83.04.2-1.6-1.7-1.7-1.9-1.6-1.6-2.0-1.7-1.8-1.7
Intermitt. access day 15 inactive lever presses1.92.12.9-1.4-1.6-1.0-1.5-1.7-0.8-1.5-1.5-1.6-1.6
Intermitt. access escalation Index2.21.92.9-1.3-1.3-1.2-1.4-1.4-1.1-1.7-1.4-1.6-1.3
Intermittent access day 1 total infusions0.40.41.2-0.5-0.7-0.1-0.6-0.7-0.3-1.1-0.6-0.6-0.7
Intermittent access day 15 total infusions0.80.91.1-0.8-1.0-0.7-1.0-1.0-0.7-0.9-1.0-0.9-1.0
Intermittent access terminal intake (last 3 days)1.11.11.6-0.9-1.2-0.9-1.1-1.3-1.1-0.9-1.1-1.1-1.2
Intermittent access total infusions0.80.81.4-0.7-1.0-0.5-0.9-1.1-0.6-1.2-0.9-0.9-1.0
Intermittent access day 1 locomotion1.31.33.5-1.0-1.2-0.4-1.2-1.0-0.5-1.9-1.2-1.1-1.2
Intermittent access day 15 total locomotion0.50.60.7-0.6-0.8-0.6-0.8-0.8-0.8-0.8-0.8-0.7-0.8
Intermittent access total locomotion1.21.33.1-1.0-1.2-0.6-1.3-1.1-0.7-1.7-1.2-1.1-1.2
Intermittent access standard deviation0.40.52.80.60.3-0.50.40.5-0.31.70.40.60.3
Cocaine induced anxiety6.17.08.0-2.5-2.7-2.8-2.8-2.4-2.7-2.6-2.7-2.5-2.7
Post-drug Anxiety1.51.72.7-1.6-1.4-1.4-1.6-0.7-0.9-1.1-1.7-0.8-1.4
Baseline Anxiety7.88.311.02.62.92.52.83.12.73.32.83.12.9
Lifetime Intake0.20.20.4-0.3-0.5-0.2-0.5-0.6-0.3-0.7-0.4-0.5-0.5
Incentive Sensitization - Responses0.00.00.10.1-0.1-0.3-0.2-0.2-0.3-0.1-0.0-0.2-0.1
Incentive Sensitization - Breakpoint0.00.00.10.1-0.1-0.3-0.1-0.2-0.40.0-0.0-0.2-0.1
Progressive ratio test 1 active lever presses1.01.02.6-0.7-0.9-0.4-1.0-1.2-0.6-1.6-0.9-1.3-0.9
Progressive ratio test 1 breakpoint1.11.23.2-0.7-1.0-0.4-1.0-1.3-0.6-1.8-0.9-1.4-1.0
Progressive ratio test 1 inactive lever presses4.34.65.7-2.1-2.3-1.8-2.2-2.3-1.7-2.2-2.2-2.4-2.3
Progressive ratio test 2 active lever presses0.60.61.3-0.6-0.8-0.5-0.8-0.8-0.6-1.2-0.8-0.8-0.8
Progressive ratio test 2 breakpoint0.70.71.3-0.7-0.9-0.5-0.9-0.9-0.6-1.1-0.8-0.9-0.9
Progressive ratio test 2 inactive lever presses0.70.81.0-0.7-1.0-0.9-1.0-0.9-0.9-0.8-1.0-0.9-1.0
Total sessions with >9 infusions0.60.71.31.10.90.50.80.60.41.10.90.70.9
Short access day 1 total inactive lever presses0.30.40.5-0.4-0.5-0.6-0.6-0.6-0.7-0.7-0.5-0.7-0.5
Short access day 10 total inactive lever presses4.34.85.2-2.2-2.3-2.3-2.3-2.1-2.1-1.9-2.3-2.2-2.3
Short access day 1 total infusions1.21.21.81.31.10.91.11.20.91.21.11.21.1
Short access day 10 total infusions0.70.81.6-0.6-0.9-0.6-0.9-1.0-0.8-1.3-0.7-1.0-0.9
Short access total infusions0.00.00.10.30.10.30.1-0.00.2-0.10.20.00.1
Short access day 1 locomotion0.20.20.60.80.50.20.40.6-0.10.40.50.60.5
Short access day 10 total locomotion0.10.10.30.40.30.00.30.5-0.20.50.30.50.3
Short access total locomotion0.60.61.31.10.80.40.70.80.10.70.80.80.8
Compulsive drug intake1.01.02.6-1.3-0.9-0.5-1.2-0.8-0.3-1.6-1.0-1.0-0.9
One hour access (0.3 mA shock)1.41.63.3-1.2-1.3-0.6-1.4-1.5-0.6-1.8-1.3-1.4-1.3
One hour access (shock baseline)0.20.30.6-0.2-0.5-0.3-0.4-0.8-0.6-0.7-0.4-0.6-0.5
Number of responses in last shaping day1.61.72.8-0.9-1.1-1.5-1.1-1.5-1.7-1.1-0.9-1.7-1.1
Context. condit. distance diff. score0.30.30.5-0.7-0.7-0.5-0.5-0.70.1-0.5-0.7-0.5-0.7
Locomotion velocity, session 13.94.28.72.22.21.02.02.10.72.92.22.12.2
Locomotion distance, session 12.43.13.91.61.61.81.71.72.01.81.61.91.6
Locomotion velocity, session 25.66.67.62.72.72.42.62.82.12.52.72.72.7
Locomotion distance, session 20.50.72.10.70.71.40.80.71.4-0.00.70.70.7
Locomotion velocity, session 31.72.03.31.41.40.81.41.60.71.81.41.61.4
Locomotion distance, session 34.44.86.42.22.21.82.32.21.92.52.22.42.2
Stereotopy head waving bouts, day 30.20.30.50.60.60.10.50.70.10.70.60.60.6
Stereotopy head waving duration, day 30.10.10.30.30.3-0.00.40.40.00.60.30.40.3
Locomotion velocity, session 71.11.22.41.11.10.71.21.00.81.51.11.11.1
Locomotion distance, session 73.64.67.02.02.02.32.21.92.61.92.02.22.0
Stereotopy head waving bouts, day 70.40.51.0-0.7-0.7-1.0-0.8-0.6-0.7-0.1-0.7-0.5-0.7
Stereotopy head waving duration, day 71.01.32.6-1.1-1.1-1.6-1.1-1.0-1.5-0.3-1.1-1.0-1.1
Locomotion velocity, session 80.40.52.60.40.4-0.10.40.60.51.60.40.60.4
Locomotion distance, session 80.20.31.2-0.4-0.40.6-0.2-0.51.1-0.8-0.4-0.2-0.4
Degree of sensitization distance0.70.72.0-0.9-0.9-0.1-0.8-0.90.1-1.4-0.9-0.9-0.9
Degree of sensitization stereotypy0.80.91.2-1.0-1.0-1.1-1.1-0.9-0.8-0.4-1.0-0.9-1.0
Condit. Reinf. active minus inactive responses2.62.94.2-1.8-1.8-1.2-1.7-1.8-1.1-2.0-1.8-1.8-1.8
Condit. Reinf. active-inactive response ratio1.21.32.2-1.2-1.2-0.7-1.1-1.2-0.5-1.5-1.2-1.2-1.2
Condit. Reinf. active responses4.45.48.0-2.4-2.4-1.6-2.3-2.5-1.6-2.8-2.4-2.5-2.4
Condit. Reinf. inactive responses1.01.21.8-1.1-1.1-0.6-1.0-1.3-0.8-1.3-1.1-1.1-1.1
Incentive salience index mean2.22.73.4-1.7-1.7-1.2-1.6-1.8-1.2-1.8-1.7-1.8-1.7
Condit. Reinf. lever presses0.10.10.2-0.3-0.3-0.0-0.3-0.4-0.0-0.3-0.3-0.4-0.3
Time in familiar zone, hab. session 10.10.10.40.20.20.60.10.30.6-0.50.20.30.2
Time in novel zone, hab. session 10.10.10.7-0.1-0.1-0.7-0.1-0.1-0.50.8-0.1-0.1-0.1
Total zone transitions, hab. session 10.30.41.30.40.41.00.50.61.10.20.40.70.4
Total locomotion distance, hab. session 10.30.40.7-0.8-0.8-0.0-0.6-0.70.3-0.8-0.8-0.6-0.8
Locomotion velocity, hab. session 10.40.51.2-0.8-0.80.0-0.6-0.80.3-1.1-0.8-0.7-0.8
Time in familiar zone, hab. session 20.20.20.50.40.40.60.40.40.7-0.10.40.50.4
Time in novel zone, hab. session 20.10.10.60.20.2-0.10.30.3-0.00.80.20.30.2
Total zone transitions, hab. session 20.40.52.40.30.31.40.40.31.5-0.30.30.40.3
Total locomotion distance, hab. session 20.60.72.2-0.8-0.80.4-0.7-0.90.6-1.5-0.8-0.8-0.8
Locomotion velocity, hab. session 20.81.12.7-1.1-1.10.2-0.9-1.20.3-1.6-1.1-1.1-1.1
Novel to familiar place preference ratio2.42.56.9-1.6-1.6-0.5-1.6-1.5-0.6-2.6-1.6-1.5-1.6
Novelty place preference2.32.46.6-1.6-1.6-0.5-1.5-1.5-0.6-2.6-1.6-1.4-1.6
Time in novel zone, NPP test1.92.06.3-1.5-1.5-0.3-1.4-1.3-0.4-2.5-1.5-1.3-1.5
Total zone transitions, NPP test0.40.52.20.40.41.20.50.51.50.20.40.60.4
Total locomotion distance, NPP test0.40.61.9-0.5-0.50.9-0.4-0.51.2-1.4-0.5-0.4-0.5
Locomotion velocity, NPP test0.40.62.1-0.7-0.70.7-0.5-0.70.9-1.5-0.7-0.6-0.7
Pavlov. Cond. lever latency1.21.53.51.01.11.31.21.01.91.31.11.21.1
Pavlov. Cond. magazine entry latency3.03.86.0-1.7-1.8-2.2-2.0-1.8-2.5-1.6-1.8-2.1-1.8
Pavlov. Cond. change in total contacts0.20.20.9-0.4-0.4-0.0-0.5-0.4-0.3-0.9-0.4-0.5-0.4
Pavlov. Cond. index score4.45.67.5-2.2-2.3-2.4-2.5-2.2-2.7-2.2-2.3-2.4-2.3
Pavlov. Cond. latency score3.44.47.1-1.9-2.0-2.2-2.2-1.9-2.7-1.9-2.0-2.1-2.0
Pavlov. Cond. lever contacts1.21.42.2-1.1-1.2-0.9-1.3-1.1-1.4-1.5-1.2-1.2-1.2
Pavlov. Cond. magazine entry number2.32.95.31.51.62.01.71.52.31.51.61.71.6
Pavlov. Cond. intertrial magazine entries0.10.20.6-0.2-0.20.6-0.1-0.30.7-0.7-0.2-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.4.65.87.0-2.3-2.4-2.4-2.6-2.3-2.6-2.3-2.4-2.5-2.4
Pavlov. Cond. response bias2.63.14.7-1.6-1.7-1.8-1.8-1.6-2.2-1.9-1.7-1.8-1.7
Bone: apparent density0.00.10.2-0.2-0.10.4-0.1-0.20.3-0.5-0.1-0.1-0.1
Bone surface0.10.20.5-0.3-0.4-0.6-0.5-0.4-0.7-0.5-0.4-0.4-0.4
Bone volume0.10.20.6-0.4-0.4-0.1-0.5-0.4-0.2-0.7-0.4-0.4-0.4
Bone: connectivity density0.10.20.40.40.30.60.40.30.60.20.30.30.3
Bone: cortical apparent density3.34.35.22.02.02.32.22.12.11.72.02.22.0
Bone: cortical area7.511.413.0-3.3-3.4-3.4-3.6-3.3-3.4-2.9-3.4-3.6-3.4
Bone: cortical porosity0.70.82.1-0.7-0.7-1.0-0.8-0.6-1.5-1.1-0.7-0.8-0.7
Bone: cortical porosity1.01.12.4-0.9-0.9-1.3-1.0-0.8-1.5-1.1-0.9-1.0-0.9
Bone: cortical thickness6.110.211.9-3.2-3.2-2.9-3.4-3.2-3.1-3.0-3.2-3.5-3.2
Bone: cortical thickness2.12.53.3-1.6-1.6-1.6-1.8-1.5-1.4-1.2-1.6-1.7-1.6
Bone: cortical tissue density3.85.05.92.22.22.42.32.22.31.82.22.42.2
Bone: elastic displacement1.92.13.9-1.5-1.5-0.8-1.5-1.5-0.9-2.0-1.5-1.5-1.5
Bone: elastic work7.810.113.3-3.2-3.2-2.6-3.4-3.1-2.9-3.6-3.2-3.2-3.2
Bone: endosteal estimation0.00.00.10.10.00.10.00.00.3-0.10.00.10.0
Bone: endosteal perimeter0.81.62.9-1.0-1.1-1.6-1.3-1.1-1.7-0.9-1.1-1.3-1.1
Bone: final force6.410.511.6-3.4-3.3-3.2-3.3-3.3-3.1-2.9-3.3-3.3-3.3
Bone: final moment7.412.313.3-3.6-3.6-3.3-3.6-3.5-3.3-3.4-3.6-3.5-3.6
Bone: marrow area0.00.00.10.10.00.00.00.00.30.00.00.20.0
Bone: maximum diameter2.34.37.2-1.9-1.9-2.7-2.1-1.9-2.6-1.1-1.9-2.2-1.9
Bone: maximum force6.110.611.2-3.3-3.3-3.0-3.3-3.3-3.0-3.2-3.3-3.3-3.3
Bone: maximum moment7.112.313.4-3.5-3.6-3.1-3.6-3.5-3.2-3.7-3.6-3.6-3.6
Bone: minimum diameter4.58.39.1-2.9-2.9-2.7-3.0-2.8-2.7-2.8-2.9-3.0-2.9
Bone: periosteal estimation2.34.75.4-2.1-2.2-2.2-2.3-2.2-2.1-2.0-2.2-2.2-2.2
Bone: periosteal perimeter3.86.410.4-2.3-2.3-2.9-2.6-2.3-3.2-2.0-2.3-2.7-2.3
Bone: post-yield work0.10.10.3-0.1-0.00.5-0.0-0.00.5-0.4-0.0-0.0-0.0
Bone: stiffness0.61.01.9-1.0-1.0-1.4-0.9-0.9-1.3-0.3-1.0-0.9-1.0
Bone: tissue strength2.42.35.5-1.6-1.6-0.6-1.5-1.6-0.6-2.3-1.6-1.5-1.6
Bone: trabecular number0.10.10.20.30.40.40.40.30.30.30.40.30.4
Bone: trabecular spacing0.60.81.1-1.0-1.1-0.9-1.0-1.0-0.1-0.2-1.1-0.9-1.1
Bone: trabecular thickness0.10.10.6-0.2-0.10.2-0.1-0.2-0.4-0.8-0.1-0.2-0.1
Bone: trabecular tissue density0.71.02.41.01.00.41.01.00.41.61.01.01.0
Breakpoint value in progressive ratio session0.70.81.3-1.0-1.0-0.3-1.0-0.9-0.3-1.1-1.0-0.8-1.0
Distance traveled before self-admin1.01.12.3-1.1-0.9-1.5-1.1-1.0-1.3-0.1-1.1-1.0-0.9
Distance traveled after self-admin0.50.61.2-0.6-0.70.2-0.7-1.10.3-1.1-0.8-0.9-0.7
Delta time in closed arm before/after self-admin0.20.20.6-0.1-0.3-0.8-0.5-0.2-0.8-0.2-0.4-0.3-0.3
Delta time in open arm before/after self-admin0.40.40.9-0.9-0.9-0.1-0.5-0.50.2-0.3-0.7-0.3-0.9
Diff in mean of infusions in LGA sessions0.00.00.1-0.1-0.3-0.1-0.00.20.00.2-0.20.2-0.3
Extinction: sum of active levers before priming1.21.21.61.01.11.21.01.11.30.91.11.11.1
Active lever presses in extinction session 60.30.30.6-0.6-0.7-0.5-0.8-0.4-0.3-0.4-0.7-0.5-0.7
Delta distance traveled before/after self-admin0.30.31.50.1-0.01.10.1-0.11.2-0.60.00.1-0.0
Delta ambulatory time before/after self-admin0.70.82.60.60.51.60.70.41.6-0.10.60.70.5
Time in closed arm before self-admin0.60.71.40.70.90.70.71.20.60.60.90.90.9
Time in closed arm after self-admin0.90.92.51.01.20.20.61.60.20.50.91.11.2
Time in open arm before self-admin0.10.10.40.30.4-0.20.3-0.2-0.40.60.4-0.20.4
Time in open arm after self-admin0.00.00.1-0.1-0.30.20.1-0.20.30.4-0.10.0-0.3
Sum of active levers in priming session hrs 5-60.20.20.5-0.5-0.3-0.1-0.4-0.70.0-0.6-0.4-0.7-0.3
Time to tail flick, vehicle, before self-admin0.20.20.7-0.5-0.4-0.1-0.4-0.4-0.2-0.9-0.3-0.5-0.4
Time to tail flick, vehicle, after self-admin1.71.92.61.31.51.11.31.60.91.31.51.41.5
Time to tail flick, test, before self-admin0.00.00.10.10.1-0.10.00.3-0.1-0.20.10.10.1
Time to tail flick, test, after self-admin0.10.10.4-0.3-0.2-0.7-0.30.2-0.30.5-0.20.1-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.20.10.10.40.10.20.5-0.00.10.20.1
Delta time to tail flick, test, before/after SA0.40.42.10.50.4-0.00.40.50.21.50.40.70.4
Ambulatory time before self-admin2.62.74.5-1.7-1.5-2.1-1.7-1.6-1.9-0.6-1.7-1.6-1.5
Ambulatory time after self-admin0.60.71.1-1.0-0.8-0.3-0.9-1.1-0.1-0.8-0.9-0.9-0.8
Total heroin consumption0.10.20.6-0.1-0.2-0.7-0.1-0.3-0.60.7-0.1-0.3-0.2
Area under the delay curve1.81.97.51.11.3-0.00.91.70.42.71.01.61.3
Delay disc. indifference point, 0s delay0.20.20.8-0.20.0-0.9-0.2-0.2-0.70.9-0.2-0.10.0
Delay disc. indifference point, 16s delay1.41.43.30.71.20.80.71.41.31.80.71.41.2
Delay disc. indifference point, 2s delay0.40.52.80.30.3-0.8-0.00.6-0.41.70.00.60.3
Delay disc. indifference point, 24s delay5.45.37.52.22.61.62.02.71.62.72.12.52.6
Delay disc. indifference point, 4s delay0.50.63.60.10.2-0.9-0.10.7-0.41.90.00.70.2
Delay disc. indifference point, 8s delay1.81.87.91.21.2-0.51.01.4-0.22.81.11.31.2
Delay discount exponential model param2.42.69.2-1.3-1.5-0.1-1.1-2.0-0.5-3.0-1.2-1.9-1.5
Delay discount hyperbolic model param2.12.38.6-1.2-1.30.0-0.9-1.9-0.5-2.9-1.0-1.8-1.3
Fecal boli incidents, locomotor time 10.80.91.91.20.91.41.00.41.20.11.00.40.9
Change in fecal boli incidents, locomotor task4.24.06.21.91.81.71.92.41.62.41.82.51.8
Time >=10cm from walls, locomotor time 10.10.10.30.10.00.10.1-0.00.50.60.00.10.0
Bouts of movement, locomotor time 12.22.53.51.91.41.71.51.71.60.91.71.61.4
Total resting periods, locomotor time 12.83.14.52.11.72.01.71.91.70.91.91.81.7
Rest time, locomotor task time 10.30.30.70.90.40.60.50.50.2-0.40.60.40.4
Distance moved, locomotor task time 10.80.91.6-1.3-1.0-1.1-1.0-0.8-0.8-0.2-1.1-0.8-1.0
Vertical activity count, locomotor time 10.80.81.5-1.2-0.9-0.7-0.9-1.1-0.4-0.9-0.9-1.1-0.9
Time >=10cm from walls, locomotor time 20.10.10.3-0.5-0.1-0.1-0.4-0.0-0.2-0.5-0.40.1-0.1
Bouts of movement, locomotor time 21.41.52.01.41.21.11.11.31.21.21.31.31.2
Total resting periods, locomotor time 20.90.91.51.20.90.90.80.91.00.91.00.90.9
Rest time, locomotor task time 20.10.10.30.60.20.30.20.40.2-0.20.40.30.2
Distance moved, locomotor task time 20.40.51.1-0.9-0.6-1.0-0.7-0.5-0.90.1-0.8-0.4-0.6
Vertical activity count, locomotor time 20.30.40.7-0.8-0.6-0.6-0.5-0.7-0.3-0.3-0.6-0.7-0.6
Weight adjusted by age3.74.25.1-1.8-2.1-1.9-2.1-2.3-2.0-1.8-2.2-2.1-2.1
Seeking ratio, delayed vs. immediate footshock0.91.01.7-0.7-1.1-1.2-1.0-1.2-1.3-0.1-1.1-1.0-1.1
Locomotion in novel chamber0.10.10.3-0.5-0.3-0.0-0.5-0.10.1-0.6-0.5-0.0-0.3
Locomotion in novel chamber post-restriction0.91.14.2-0.9-0.8-0.5-0.9-1.0-0.9-2.1-0.8-1.1-0.8
Progressive ratio0.50.61.11.00.81.00.70.70.90.30.60.90.8
Food seeking constrained by brief footshock0.10.10.30.50.20.10.40.40.20.60.30.50.2
Seeking ratio, punishment vs. effort0.20.20.6-0.5-0.5-0.8-0.3-0.4-0.50.2-0.3-0.5-0.5
Run reversals in cocaine runway, females0.70.61.50.40.50.80.60.91.21.00.51.10.5
Run reversals in cocaine runway, males0.40.41.1-0.3-0.4-0.5-0.5-0.7-0.9-1.0-0.4-0.7-0.4
Latency to leave start box in cocaine runway1.11.21.80.91.31.41.30.81.10.41.10.91.3
Latency to leave start box in cocaine runway, F0.20.30.70.10.50.80.50.40.8-0.00.40.50.5
Latency to leave start box in cocaine runway, M0.60.61.20.80.91.10.80.30.7-0.40.70.30.9
Cd content in liver1.51.62.81.01.01.31.21.31.71.51.11.51.0
Co content in liver0.10.10.60.20.10.70.20.10.8-0.50.10.10.1
Cu content in liver0.20.20.8-0.3-0.3-0.3-0.4-0.3-0.6-0.9-0.3-0.5-0.3
Fe content in liver0.70.81.10.90.90.91.01.00.90.50.91.10.9
K content in liver2.52.53.8-1.6-1.6-1.2-1.5-1.7-1.2-1.9-1.6-1.8-1.6
Mg content in liver0.20.21.1-0.3-0.30.4-0.2-0.50.4-1.0-0.3-0.4-0.3
Mn content in liver0.30.30.9-0.4-0.4-0.9-0.4-0.5-1.00.1-0.3-0.5-0.4
Na content in liver0.00.00.2-0.00.1-0.30.0-0.2-0.50.20.1-0.20.1
Rb content in liver1.01.32.1-1.3-1.2-0.5-1.2-1.2-0.2-1.5-1.3-1.2-1.2
Se content in liver0.30.30.5-0.6-0.7-0.5-0.5-0.5-0.3-0.6-0.6-0.5-0.7
Sr content in liver0.10.10.10.30.20.30.20.3-0.1-0.20.30.30.2
Zn content in liver0.00.00.30.20.1-0.20.00.0-0.50.00.2-0.10.1