Hub : Genes

ENSRNOG00000065898

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000065898	0.1	0.08	4.2e-03	0.01	0.03	0.03	0.01	1.4e-01	1.5e-02	8.9e-03	5.9e-02
2	Brain	gene expression	ENSRNOG00000065898	0.05	0.03	9.2e-05	0.06	0.04	0.04	0.05	4.8e-06	2.1e-04	5.5e-05	3.2e-05
3	Brain	intron excision ratio	chr12:4884760:4886951	0.07	0.04	9.5e-07	0.1	0.07	0.07	0.08	2.6e-09	6.6e-07	2.3e-07	9.2e-08
4	Brain	intron excision ratio	chr12:4884794:4886951	0.05	0.03	2.8e-05	0.04	0.04	0.04	0.04	5.4e-05	2.0e-04	2.9e-04	1.8e-04
5	PL	intron excision ratio	chr12:4884794:4886951	0.07	0.04	7.5e-05	0.03	0.06	0.04	0.03	4.5e-03	5.1e-05	4.9e-04	1.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	2.3	7.5	13.3	-3.6	-3.5	-2.1	2.6	0.8
BMI without tail	0.8	1.8	4.3	-0.9	-1.6	1.0	-0.1	-2.1
Body weight	7.4	31.5	68.3	-8.3	-8.1	-2.9	3.5	-1.6
Epididymis fat weight	1.8	4.1	6.5	-2.6	-1.9	-2.0	1.9	1.6
Glucose	0.1	0.2	0.7	0.0	0.8	0.0	-0.1	0.6
Heart weight	1.1	1.6	2.9	0.4	0.9	1.3	-1.7	-1.6
Left kidney weight	3.1	9.0	21.1	-4.6	-4.1	-1.1	0.6	-2.4
Right kidney weight	3.5	9.9	25.1	-5.0	-4.3	-1.3	1.0	-1.8
Tail length	1.8	5.4	15.1	-1.6	-2.5	1.6	-0.8	-3.9
Length with tail	5.1	18.6	40.5	-6.1	-6.4	-1.3	1.5	-3.3
Length without tail	10.0	21.8	45.6	-6.8	-6.0	-3.9	3.5	0.6
Liver weight, left	3.5	5.6	10.7	-3.3	-2.9	-2.2	2.0	0.6
Liver weight, right	3.6	5.9	15.1	-3.9	-3.4	-0.7	1.3	-1.0
Parametrial fat weight	0.0	0.0	0.1	-0.1	0.3	0.1	-0.2	-0.3
Retroperitoneal fat weight	2.6	8.6	14.5	-2.6	-1.5	-3.0	3.2	3.8
Intraocular pressure	0.5	0.7	1.9	-0.9	-1.4	-0.5	0.5	-0.2
Extensor digitorum longus weight	1.7	6.7	15.2	-3.6	-3.9	-1.2	1.5	-1.2
Soleus weight	1.3	3.9	7.5	-2.7	-2.7	-1.4	1.7	-0.1
Tibialis anterior weight	2.0	6.8	15.4	-3.6	-3.9	-0.9	1.3	-1.8
Tibia length	1.2	3.5	8.3	-2.9	-2.2	0.2	-0.5	-1.9
Number of licking bursts	2.0	2.4	4.6	-0.1	0.8	1.6	-2.0	-2.1
Food consumed during 24 hour testing period	0.8	1.0	1.5	1.2	0.5	1.2	-0.6	-1.2
Times rat made contact with spout	2.4	2.7	5.0	0.2	0.5	2.1	-1.9	-2.2
Mean time between licks in bursts	0.6	0.9	1.9	1.4	1.3	0.3	-0.7	0.3
Mean num. licks in bursts	0.1	0.1	0.3	0.3	-0.4	-0.1	0.5	0.4
Std. dev. time between licks in bursts	0.1	0.1	0.3	0.2	0.1	0.1	-0.4	-0.6
Water consumed over 24 hours	1.3	1.6	4.7	-0.2	-0.2	0.9	-1.5	-2.2
Indifference point 0 sec	2.0	3.2	4.2	-2.0	-1.8	-2.0	1.7	1.2
Indifference point AUC	0.4	0.5	0.9	-0.8	-1.0	-0.3	0.5	-0.7
Indifference point function ln k	0.2	0.3	0.8	-0.2	0.3	0.6	-0.9	-0.6
Indifference point function log k	0.2	0.3	0.8	-0.2	0.3	0.6	-0.9	-0.6
Delay discounting total patch changes 0 sec	2.2	3.6	4.6	-2.2	-2.0	-2.1	1.8	1.2
Delay discounting total patch changes 12 sec	4.1	5.4	7.7	-2.3	-2.2	-2.7	2.8	1.5
Delay discounting total patch changes 18 sec	1.1	1.4	2.3	-1.0	-1.2	-1.4	1.5	0.7
Delay discounting total patch changes 24 sec	1.8	2.3	3.8	-1.6	-1.7	-1.3	2.0	0.8
Delay discounting total patch changes 6 sec	1.4	2.2	3.2	-1.6	-1.8	-1.5	1.6	0.5
Delay discounting time to switch 0 sec	1.0	1.5	3.2	1.4	1.2	-0.6	0.8	1.8
Delay discounting water rate 0 sec	1.7	2.7	5.7	-2.4	-2.4	-0.3	-0.1	-1.5
Delay discounting water rate 12 sec	0.6	1.0	1.8	-0.5	-0.0	1.1	-1.3	-1.3
Delay discounting water rate 18 sec	0.8	1.1	2.4	0.5	0.5	1.6	-1.2	-1.2
Delay discounting water rate 24 sec	1.4	1.9	4.9	-0.9	-1.1	1.3	-0.9	-2.2
Delay discounting water rate 6 sec	0.3	0.5	1.3	-1.2	-1.0	-0.1	0.5	-0.2
Locomotor activity	0.8	1.3	3.6	-0.4	-0.4	1.3	-1.1	-1.9
Locomotor testing distance	0.3	0.5	1.4	-0.4	-0.4	0.9	-0.4	-1.2
Locomotor testing rearing	0.1	0.1	0.2	0.4	0.3	0.4	-0.2	0.2
Light reinforcement 1	0.7	1.3	2.9	1.6	1.7	0.4	-0.4	0.8
Light reinforcement 2	0.2	0.2	0.5	0.7	0.7	-0.0	-0.3	0.2
Reaction time number correct	0.5	0.7	1.2	-1.1	-0.6	0.2	-0.7	-1.1
Reaction time mean minus median	1.7	2.2	4.1	2.0	1.4	1.7	-1.1	-0.9
Reaction time mean minus median AUC	2.2	2.8	5.4	2.3	2.0	1.5	-1.4	-0.6
Reaction time num false alarms	0.2	0.3	0.6	0.5	0.4	0.8	-0.2	-0.6
Reaction time num false alarms AUC	0.1	0.1	0.2	-0.2	-0.3	0.2	0.5	-0.2
Reaction time trials correct on left	0.5	0.7	1.2	-1.1	-0.6	0.2	-0.7	-1.1
Reaction time trials on left	0.4	0.6	1.3	-1.0	-0.5	0.2	-0.7	-1.1
Reaction time mean	3.6	5.0	11.0	3.3	3.3	0.9	-1.4	0.7
Reaction time mean AUC	3.4	4.5	10.3	3.2	3.1	0.7	-1.3	0.8
Median of all reaction times	3.6	4.8	11.0	3.2	3.3	0.3	-1.1	1.3
Reaction time omissions	1.3	1.7	4.0	2.0	2.0	0.6	-0.6	0.2
Reaction time false alarm rate	0.1	0.1	0.4	0.3	0.0	0.1	0.6	0.3
Reaction time premature initiation rate	1.7	2.3	5.0	2.2	1.1	2.0	-0.7	-0.8
Reaction time premature initiations	1.1	1.6	3.4	1.5	0.7	1.8	-0.8	-1.2
Std. dev. reaction times	2.4	3.3	7.1	2.7	2.4	1.5	-1.2	-0.3
Reaction time trials completed	0.4	0.6	1.3	-1.0	-0.5	0.2	-0.7	-1.1
Reaction time trials AUC	0.4	0.5	1.1	-1.1	-0.6	0.1	-0.6	-0.9
Social response proportion	2.3	2.5	6.1	0.1	0.2	1.5	-2.0	-2.5
Social responses	1.0	1.3	3.4	0.3	-0.0	1.5	-0.9	-1.8
Social time	1.8	2.3	6.1	1.9	2.5	0.8	-1.2	0.4
Conditioned locomotion	1.9	2.3	4.1	-1.2	-1.9	-1.1	2.0	0.7
Cocaine response after cond. corrected	0.5	0.5	0.9	-0.1	-0.6	-0.8	0.9	1.0
Cocaine response after cond. not corrected	1.1	1.2	2.2	-0.2	-0.9	-1.0	1.5	1.3
Cocaine response before conditioning	0.5	0.6	1.4	-0.4	-0.7	-0.6	1.2	0.7
Saline control response	2.0	2.6	7.2	0.2	-0.1	1.8	-1.7	-2.7
Condit. Reinf. active minus inactive responses	0.9	1.1	2.5	0.6	0.6	1.0	-1.1	-1.6
Condit. Reinf. active-inactive response ratio	1.7	1.8	2.4	1.2	1.2	1.3	-1.6	-1.4
Condit. Reinf. active responses	0.3	0.4	1.5	0.1	0.1	0.7	-0.4	-1.2
Condit. Reinf. inactive responses	0.3	0.4	0.6	-0.7	-0.8	-0.4	0.7	-0.1
Condit. Reinf. lever presses	1.2	1.6	2.1	-1.3	-1.4	-1.4	1.4	0.6
Condit. Reinf. lever reinforcers received	0.3	0.5	1.3	0.2	0.3	0.8	-0.6	-1.1
Pavlov. Cond. lever latency	0.0	0.0	0.0	0.0	0.2	0.2	-0.0	-0.2
Pavlov. Cond. magazine entry latency	0.7	0.8	1.6	1.2	1.2	-0.0	-0.6	0.8
Pavlov. Cond. change in total contacts	0.0	0.0	0.2	-0.1	0.1	0.1	-0.4	-0.1
Pavlov. Cond. index score	0.1	0.1	0.2	0.4	0.3	-0.1	-0.1	0.4
Pavlov. Cond. latency score	0.1	0.1	0.3	0.4	0.3	-0.2	-0.0	0.6
Pavlov. Cond. lever contacts	0.3	0.5	0.9	-0.2	-0.5	-0.9	0.7	0.9
Pavlov. Cond. magazine entry number	0.6	0.8	1.6	-1.0	-1.3	-0.1	0.9	-0.7
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.8	-0.3	-0.3	0.8	-0.3	-1.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.3	0.5	0.5	0.1	-0.4	0.3
Pavlov. Cond. response bias	0.3	0.4	1.0	0.3	-0.0	-0.8	0.4	1.0
Conditioned reinforcement - actives	1.2	1.2	3.5	-0.7	-1.0	1.0	-0.4	-1.9
Conditioned reinforcement - inactives	0.2	0.2	0.3	0.5	0.4	0.2	-0.5	-0.6
Conditioned locomotion	1.0	1.1	3.1	-0.1	-0.7	1.4	-0.3	-1.8
Intermittent access intake day 1-15 change	0.4	0.4	1.1	-0.1	-0.4	0.7	-0.3	-1.0
Intermittent access intake escalation	0.4	0.4	1.3	-0.2	-0.5	0.7	-0.3	-1.1
Intermittent access intake escalation 2	0.1	0.1	0.2	0.0	-0.3	0.4	0.0	-0.4
Intermitt. access day 1 inactive lever presses	0.7	0.8	1.4	0.3	0.8	0.6	-1.2	-1.1
Intermitt. access day 15 inactive lever presses	0.5	0.5	1.3	0.3	0.2	-0.9	0.6	1.1
Intermitt. access escalation Index	0.3	0.3	0.9	0.3	0.6	0.1	-1.0	-0.3
Intermittent access day 1 total infusions	1.0	1.2	3.9	2.0	1.3	0.6	0.0	0.2
Intermittent access day 15 total infusions	0.7	0.8	1.9	1.4	0.5	1.1	-0.2	-0.9
Intermittent access terminal intake (last 3 days)	0.6	0.6	2.2	1.5	0.7	0.6	0.3	-0.1
Intermittent access total infusions	1.2	1.4	4.5	2.1	1.2	0.9	-0.0	-0.1
Intermittent access day 1 locomotion	1.6	1.7	4.6	2.1	1.7	0.7	0.1	0.4
Intermittent access day 15 total locomotion	1.7	1.9	3.3	1.6	1.1	1.8	-0.9	-1.2
Intermittent access total locomotion	2.1	2.4	5.3	2.3	1.9	1.6	-0.6	-0.4
Intermittent access standard deviation	0.1	0.1	0.3	0.0	-0.4	0.2	0.6	-0.1
Cocaine induced anxiety	0.7	0.8	1.1	-0.6	-1.0	-0.7	1.1	0.9
Post-drug Anxiety	1.2	1.3	3.4	1.9	1.4	0.6	0.1	1.0
Baseline Anxiety	2.4	2.6	6.7	2.2	2.6	0.5	-0.6	1.0
Lifetime Intake	0.8	0.9	3.2	1.8	0.9	0.4	0.4	0.3
Incentive Sensitization - Responses	1.1	1.1	1.8	1.2	0.8	1.4	-0.7	-1.0
Incentive Sensitization - Breakpoint	1.1	1.1	1.8	1.2	0.8	1.3	-0.7	-1.0
Progressive ratio test 1 active lever presses	0.2	0.3	0.8	0.2	-0.1	0.6	-0.2	-0.9
Progressive ratio test 1 breakpoint	0.4	0.5	1.1	0.6	0.2	0.9	-0.3	-1.0
Progressive ratio test 1 inactive lever presses	0.6	0.6	1.8	0.3	0.3	0.7	-0.8	-1.3
Progressive ratio test 2 active lever presses	1.4	1.5	3.7	0.8	0.1	1.6	-0.8	-1.9
Progressive ratio test 2 breakpoint	2.1	2.3	4.0	1.3	0.7	2.0	-1.2	-2.0
Progressive ratio test 2 inactive lever presses	1.2	1.3	4.7	0.2	-0.2	1.2	-0.7	-2.2
Total sessions with >9 infusions	0.3	0.3	0.6	-0.2	-0.5	-0.6	0.8	0.4
Short access day 1 total inactive lever presses	0.5	0.6	1.0	0.5	0.6	0.7	-1.0	-0.9
Short access day 10 total inactive lever presses	0.6	0.6	2.1	-0.1	-0.5	0.7	-0.5	-1.5
Short access day 1 total infusions	1.3	1.4	2.9	0.3	0.1	-1.1	1.6	1.7
Short access day 10 total infusions	0.7	0.8	1.7	1.1	0.3	-0.1	1.3	1.1
Short access total infusions	0.7	0.7	1.3	1.0	0.4	-0.5	1.0	1.1
Short access day 1 locomotion	1.3	1.4	3.3	1.7	1.8	0.8	-0.3	0.3
Short access day 10 total locomotion	0.5	0.6	0.9	0.7	1.0	-0.2	0.8	0.9
Short access total locomotion	0.9	1.0	2.1	1.4	1.3	0.3	0.6	0.8
Compulsive drug intake	1.5	1.4	3.0	1.5	1.7	0.7	-1.2	0.2
One hour access (0.3 mA shock)	3.7	4.3	7.1	2.7	1.9	2.1	-1.7	-1.8
One hour access (shock baseline)	0.8	1.0	2.3	0.9	0.3	1.2	-0.6	-1.5
Number of responses in last shaping day	0.0	0.0	0.1	0.2	0.2	0.1	-0.2	-0.3
Context. condit. distance diff. score	2.9	3.5	7.5	-2.2	-2.7	-1.5	1.7	0.2
Locomotion velocity, session 1	0.6	0.7	1.9	0.8	0.7	1.4	-0.3	-0.4
Locomotion distance, session 1	0.6	0.8	1.6	1.2	1.3	0.9	-0.1	0.1
Locomotion velocity, session 2	2.3	2.7	5.2	1.3	1.7	2.3	-1.5	-1.2
Locomotion distance, session 2	2.1	3.0	4.7	1.7	2.2	2.1	-1.3	-1.1
Locomotion velocity, session 3	0.4	0.4	0.9	-0.6	-0.3	-0.7	0.9	0.6
Locomotion distance, session 3	0.1	0.1	0.4	0.1	0.1	-0.2	0.6	0.2
Stereotopy head waving bouts, day 3	0.5	0.6	1.7	-0.4	-1.1	0.1	0.0	-1.3
Stereotopy head waving duration, day 3	0.0	0.0	0.0	0.2	-0.2	-0.2	0.1	0.0
Locomotion velocity, session 7	0.3	0.4	0.8	0.6	0.9	-0.3	-0.4	0.7
Locomotion distance, session 7	0.1	0.2	0.4	0.5	0.6	-0.3	-0.3	0.2
Stereotopy head waving bouts, day 7	1.8	2.1	4.5	2.1	1.8	1.5	-0.7	-0.3
Stereotopy head waving duration, day 7	1.7	2.0	3.3	1.7	1.8	1.6	-1.1	-0.3
Locomotion velocity, session 8	0.5	0.6	1.8	0.6	0.3	1.4	-0.4	-0.8
Locomotion distance, session 8	0.4	0.6	1.3	-0.9	-1.1	-0.1	0.9	-0.5
Degree of sensitization distance	1.0	1.0	1.7	1.1	1.2	0.7	-1.3	-0.2
Degree of sensitization stereotypy	1.4	1.5	2.9	1.7	1.5	1.4	-0.7	-0.1
Condit. Reinf. active minus inactive responses	0.8	0.9	1.4	-1.2	-0.6	-0.8	0.8	1.1
Condit. Reinf. active-inactive response ratio	0.8	0.8	1.3	-1.0	-0.6	-1.1	0.6	1.1
Condit. Reinf. active responses	0.2	0.2	0.5	-0.7	-0.3	0.0	0.5	0.4
Condit. Reinf. inactive responses	0.4	0.5	1.3	0.7	0.7	1.1	-0.3	-0.4
Incentive salience index mean	0.8	1.0	1.4	-1.0	-0.8	-0.9	1.2	1.1
Condit. Reinf. lever presses	0.6	0.8	1.9	-0.5	-0.8	-0.9	1.4	0.8
Time in familiar zone, hab. session 1	0.2	0.2	0.5	-0.1	0.2	-0.6	0.1	0.7
Time in novel zone, hab. session 1	0.3	0.3	0.6	-0.5	-0.2	0.7	-0.3	-0.6
Total zone transitions, hab. session 1	1.7	2.4	4.3	2.1	1.9	1.7	-0.8	-0.6
Total locomotion distance, hab. session 1	0.5	0.7	1.5	1.2	1.0	-0.3	0.6	0.9
Locomotion velocity, hab. session 1	1.1	1.6	4.2	2.1	1.6	-0.0	0.4	1.0
Time in familiar zone, hab. session 2	0.4	0.5	1.0	-0.6	-0.2	-1.0	0.0	1.0
Time in novel zone, hab. session 2	0.3	0.3	0.6	0.7	0.5	0.7	0.0	-0.4
Total zone transitions, hab. session 2	2.3	3.0	4.7	1.5	1.5	2.2	-1.6	-1.8
Total locomotion distance, hab. session 2	1.2	1.6	3.8	2.0	1.6	1.0	-0.7	-0.5
Locomotion velocity, hab. session 2	1.4	1.9	4.2	2.1	1.7	1.1	-0.8	-0.6
Novel to familiar place preference ratio	1.6	1.7	2.2	1.2	1.5	1.5	-1.4	-0.7
Novelty place preference	1.6	1.7	2.9	1.2	1.7	1.3	-1.4	-0.5
Time in novel zone, NPP test	1.2	1.2	1.9	0.9	1.4	1.2	-1.3	-0.5
Total zone transitions, NPP test	0.5	0.7	1.6	0.6	0.6	1.3	-0.6	-1.1
Total locomotion distance, NPP test	0.4	0.5	1.7	1.3	0.8	0.2	0.4	0.1
Locomotion velocity, NPP test	0.6	0.8	2.5	1.6	1.0	0.7	-0.0	-0.4
Pavlov. Cond. lever latency	0.7	0.9	2.8	-1.7	-1.0	-0.7	-0.4	-0.5
Pavlov. Cond. magazine entry latency	0.6	0.8	1.9	0.6	0.0	1.2	-0.6	-1.4
Pavlov. Cond. change in total contacts	0.2	0.2	0.7	0.3	0.1	0.1	0.8	0.6
Pavlov. Cond. index score	0.1	0.2	0.4	0.6	-0.0	0.5	0.3	-0.3
Pavlov. Cond. latency score	0.2	0.3	0.7	0.9	0.2	0.7	0.3	-0.3
Pavlov. Cond. lever contacts	0.5	0.6	2.1	1.4	0.6	0.4	0.5	0.5
Pavlov. Cond. magazine entry number	0.4	0.5	1.4	-0.3	0.2	-0.9	0.4	1.2
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	-0.2	0.3	0.0	-0.2	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	0.6	-0.2	0.3	0.4	-0.2
Pavlov. Cond. response bias	0.2	0.2	0.5	0.5	-0.3	0.7	0.1	-0.6
Bone: apparent density	6.5	10.8	18.8	-4.3	-4.2	-3.2	2.6	0.6
Bone surface	5.7	10.0	18.5	-4.3	-4.2	-2.8	2.5	0.2
Bone volume	7.0	11.8	18.0	-4.2	-4.1	-3.7	3.0	1.4
Bone: connectivity density	5.3	8.3	16.5	-4.1	-4.0	-2.2	1.9	-0.5
Bone: cortical apparent density	0.1	0.2	0.5	-0.2	0.2	-0.6	0.2	0.7
Bone: cortical area	2.6	4.0	7.1	-2.7	-2.5	-2.0	1.6	0.3
Bone: cortical porosity	1.0	1.1	2.3	1.5	1.1	1.1	-0.7	-0.7
Bone: cortical porosity	1.4	1.5	3.0	1.7	1.4	1.2	-0.9	-0.6
Bone: cortical thickness	2.3	3.8	6.2	-2.5	-2.3	-2.0	1.7	0.3
Bone: cortical thickness	0.3	0.3	1.0	-0.4	-0.6	-0.1	-0.2	-1.0
Bone: cortical tissue density	0.1	0.2	0.5	-0.1	0.2	-0.6	0.2	0.7
Bone: elastic displacement	1.4	1.6	2.2	1.3	1.0	1.5	-0.9	-1.5
Bone: elastic work	1.0	1.4	2.7	-1.4	-1.4	0.0	0.1	-1.7
Bone: endosteal estimation	0.3	0.7	1.7	-0.8	-0.7	0.6	-0.7	-1.3
Bone: endosteal perimeter	0.8	1.6	3.6	-1.9	-1.9	-0.8	0.5	-0.4
Bone: final force	1.0	1.6	3.5	-1.9	-1.7	-0.6	0.2	-1.0
Bone: final moment	0.8	1.3	3.1	-1.8	-1.6	-0.4	0.2	-1.0
Bone: marrow area	0.4	0.8	1.8	-0.7	-0.7	0.6	-0.8	-1.3
Bone: maximum diameter	1.4	2.6	5.1	-2.3	-2.2	-1.4	1.0	-0.1
Bone: maximum force	1.6	2.8	5.6	-2.4	-2.2	-1.5	1.0	-0.5
Bone: maximum moment	1.4	2.4	5.1	-2.3	-2.1	-1.3	0.9	-0.5
Bone: minimum diameter	0.0	0.0	0.1	0.1	0.3	-0.0	-0.2	0.1
Bone: periosteal estimation	0.8	1.6	3.6	-1.9	-1.7	-0.6	0.3	-0.8
Bone: periosteal perimeter	1.7	2.8	5.2	-2.3	-2.0	-1.8	1.1	0.4
Bone: post-yield work	1.6	2.1	3.1	-1.3	-1.7	-1.5	1.8	0.9
Bone: stiffness	0.8	1.3	2.1	-1.5	-1.3	-1.3	0.8	0.1
Bone: tissue strength	0.3	0.3	0.5	-0.7	-0.4	-0.5	0.6	0.2
Bone: trabecular number	4.8	7.5	14.5	-3.8	-3.6	-2.5	1.8	0.1
Bone: trabecular spacing	1.3	1.6	3.8	1.7	1.9	0.4	-0.4	1.2
Bone: trabecular thickness	5.6	6.7	12.1	-3.4	-3.5	-2.4	2.1	0.3
Bone: trabecular tissue density	0.3	0.4	0.8	0.2	0.7	-0.9	-0.2	0.8
Breakpoint value in progressive ratio session	0.1	0.1	0.1	0.2	-0.2	0.1	0.4	-0.3
Distance traveled before self-admin	0.4	0.4	0.7	0.6	0.8	-0.3	0.3	0.9
Distance traveled after self-admin	0.1	0.1	0.2	-0.3	-0.2	-0.4	-0.0	-0.0
Delta time in closed arm before/after self-admin	0.7	0.7	2.2	0.3	0.6	0.4	-1.5	-0.7
Delta time in open arm before/after self-admin	1.7	1.6	2.8	1.7	1.2	0.1	1.1	1.6
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	0.2	-0.0	0.1	0.2	-0.0
Extinction: sum of active levers before priming	0.7	0.7	1.4	-0.7	-0.4	-1.1	0.7	1.2
Active lever presses in extinction session 6	1.4	1.3	2.7	-1.6	-1.0	-1.4	0.8	0.6
Delta distance traveled before/after self-admin	0.3	0.3	0.9	-0.4	-0.6	0.2	-0.5	-0.9
Delta ambulatory time before/after self-admin	0.1	0.1	0.2	-0.5	-0.4	-0.3	-0.0	-0.3
Time in closed arm before self-admin	0.5	0.5	1.4	-0.4	-0.5	0.9	-0.3	-1.2
Time in closed arm after self-admin	1.4	1.4	3.1	-0.4	0.1	1.0	-1.7	-1.8
Time in open arm before self-admin	0.3	0.3	0.8	-0.9	-0.3	-0.5	-0.6	-0.4
Time in open arm after self-admin	0.3	0.3	0.6	0.7	0.4	0.1	0.7	0.8
Sum of active levers in priming session hrs 5-6	2.0	1.9	3.8	-0.8	-0.7	-1.5	1.9	1.6
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.5	0.5	0.7	0.1	-0.4	0.1
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.5	-0.4	0.2	-0.7	-0.2	0.5
Time to tail flick, test, before self-admin	1.5	1.5	2.6	-1.6	-1.4	-1.3	1.0	0.2
Time to tail flick, test, after self-admin	1.4	1.5	2.2	-1.1	-0.9	-1.3	1.5	1.1
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.7	-0.6	-0.2	-1.3	0.4	1.2
Delta time to tail flick, test, before/after SA	0.2	0.2	0.3	0.5	0.5	0.4	0.2	0.5
Ambulatory time before self-admin	0.2	0.2	0.3	0.5	0.4	-0.2	0.6	0.6
Ambulatory time after self-admin	0.2	0.2	0.5	-0.3	-0.4	-0.5	0.7	0.2
Total heroin consumption	1.3	1.5	3.4	1.6	1.9	0.5	0.3	1.2
Area under the delay curve	0.6	0.7	1.5	1.2	1.2	0.4	-0.3	0.3
Delay disc. indifference point, 0s delay	0.2	0.3	0.5	0.1	0.7	-0.5	-0.3	0.6
Delay disc. indifference point, 16s delay	0.6	0.6	1.4	1.2	1.0	0.4	0.3	0.5
Delay disc. indifference point, 2s delay	0.9	1.0	1.8	1.3	1.3	-0.2	0.4	1.2
Delay disc. indifference point, 24s delay	1.9	1.8	3.5	1.7	1.9	1.1	-1.2	0.1
Delay disc. indifference point, 4s delay	0.6	0.6	1.1	0.9	0.8	-0.2	0.8	1.0
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	0.5	0.5	-0.1	-0.3	0.0
Delay discount exponential model param	0.8	0.8	1.9	-1.4	-1.3	-0.5	0.4	-0.3
Delay discount hyperbolic model param	0.8	0.8	1.8	-1.4	-1.3	-0.4	0.2	-0.4
Fecal boli incidents, locomotor time 1	0.2	0.2	0.7	-0.5	-0.2	0.4	-0.2	-0.8
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.5	0.3	0.0	-0.1	0.4
Time >=10cm from walls, locomotor time 1	1.0	1.0	2.3	-0.0	0.1	-1.3	0.9	1.5
Bouts of movement, locomotor time 1	0.6	0.7	1.3	-0.7	-1.1	0.2	-0.5	-1.1
Total resting periods, locomotor time 1	0.5	0.6	1.3	-0.7	-1.1	0.2	-0.4	-0.9
Rest time, locomotor task time 1	0.5	0.6	1.3	-0.1	-0.9	1.1	0.3	-0.8
Distance moved, locomotor task time 1	0.3	0.4	1.0	0.0	0.7	-1.0	-0.6	0.1
Vertical activity count, locomotor time 1	0.3	0.3	0.8	-0.5	0.1	-0.4	-0.9	-0.5
Time >=10cm from walls, locomotor time 2	0.9	1.0	1.7	-1.1	-0.7	-0.6	1.3	0.9
Bouts of movement, locomotor time 2	1.3	1.4	3.4	-1.8	-1.6	-0.8	0.6	-0.2
Total resting periods, locomotor time 2	1.6	1.7	3.8	-2.0	-1.8	-0.9	0.8	0.1
Rest time, locomotor task time 2	0.4	0.5	1.3	-0.3	-0.9	-0.1	1.2	0.5
Distance moved, locomotor task time 2	0.8	0.9	2.3	0.1	0.8	0.5	-1.5	-1.1
Vertical activity count, locomotor time 2	1.2	1.3	3.2	-0.7	-0.4	0.4	-1.6	-1.8
Weight adjusted by age	0.4	0.5	0.9	-0.8	-0.5	0.7	0.2	-1.0
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	1.0	1.0	0.7	0.2	-0.1	0.7
Locomotion in novel chamber	2.8	3.5	6.1	1.2	0.9	2.5	-1.7	-2.5
Locomotion in novel chamber post-restriction	2.6	3.1	9.3	0.0	-0.5	1.5	-1.9	-3.1
Progressive ratio	0.3	0.3	0.7	0.4	0.5	0.8	0.6	0.4
Food seeking constrained by brief footshock	0.2	0.2	0.5	-0.5	-0.7	-0.2	0.6	0.4
Seeking ratio, punishment vs. effort	0.3	0.4	0.8	-0.6	-0.9	-0.6	-0.5	-0.6
Run reversals in cocaine runway, females	0.5	0.5	1.2	1.1	1.0	0.0	0.0	0.4
Run reversals in cocaine runway, males	0.6	0.6	1.5	-1.0	-0.6	-1.2	-0.4	-0.1
Latency to leave start box in cocaine runway	0.3	0.4	1.1	-0.7	-0.0	-0.4	0.1	1.1
Latency to leave start box in cocaine runway, F	0.6	0.6	1.2	-0.9	-0.4	-1.0	0.1	1.1
Latency to leave start box in cocaine runway, M	0.3	0.3	1.2	-0.1	0.1	1.1	-0.2	-0.2
Cd content in liver	2.3	2.5	3.4	1.8	1.8	1.5	-1.7	-0.9
Co content in liver	1.1	1.3	2.4	1.2	0.5	1.5	-0.9	-1.3
Cu content in liver	0.7	0.9	2.6	-1.6	-0.9	-0.8	0.5	0.4
Fe content in liver	7.5	8.9	17.3	-4.2	-3.6	-2.7	2.3	1.1
K content in liver	0.1	0.1	0.2	0.5	0.1	0.1	0.4	0.1
Mg content in liver	0.4	0.4	0.8	0.9	0.6	0.6	-0.4	-0.6
Mn content in liver	0.5	0.6	1.3	0.9	1.1	0.3	-0.8	0.1
Na content in liver	0.3	0.3	0.6	-0.6	-0.8	-0.6	0.2	0.3
Rb content in liver	1.1	1.4	3.7	0.6	0.5	-1.3	1.1	1.9
Se content in liver	4.0	4.8	6.3	-1.9	-2.2	-2.5	2.5	1.7
Sr content in liver	0.3	0.3	0.6	-0.5	-0.5	0.5	-0.2	-0.8
Zn content in liver	1.4	1.5	4.2	-2.0	-1.5	0.4	0.3	-0.9