Hub : Genes

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Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method.

Trait associations

For each tested trait, stats based on TWAS chi² (squared Z-score) for the above models are shown. Avg chi² ratio is the mean chi² across all models for this gene, divided by the mean chi² across all models for all genes. Avg chi² is the mean chi² across all models for this gene. Max chi² is the highest chi² across all models for this gene.

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.