Hub : Genes

Rap2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000065432 0.23 0.14 0.0e+00 0.2 0.21 0.2 0.2 2.4e-21 6.7e-23 2.6e-21 1.7e-21
2 BLA gene expression ENSRNOG00000065432 0.27 0.24 5.9e-10 0.15 0.16 0.15 0.16 2.6e-08 6.5e-09 1.6e-08 7.6e-09
3 Brain gene expression ENSRNOG00000065432 0.13 0.1 8.6e-11 0.11 0.11 0.12 0.1 1.4e-10 2.6e-10 1.5e-11 8.5e-10
4 Liver gene expression ENSRNOG00000065432 0.03 0.03 5.0e-04 0.02 0.02 0.03 0.02 2.5e-03 2.5e-03 8.5e-04 4.7e-03
5 NAcc gene expression ENSRNOG00000065432 0.14 0.11 1.7e-08 0.09 0.07 0.13 0.08 5.7e-07 5.8e-06 8.0e-10 1.3e-06
6 OFC gene expression ENSRNOG00000065432 0.26 0.2 2.3e-03 0.03 0.05 0 0.03 7.8e-02 2.5e-02 2.8e-01 6.7e-02
7 PL gene expression ENSRNOG00000065432 0.11 0.1 1.3e-06 0.06 0.06 0.06 0.06 1.7e-05 3.7e-05 3.0e-05 3.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.10.50.8-0.7-0.0-0.8-0.7-0.6-0.7-0.9
BMI without tail0.30.70.90.80.71.00.80.80.80.9
Body weight0.10.30.7-0.60.6-0.7-0.4-0.3-0.6-0.8
Epididymis fat weight2.35.39.62.23.12.31.92.42.22.0
Glucose0.20.20.4-0.5-0.2-0.5-0.6-0.4-0.5-0.6
Heart weight1.11.64.51.12.11.11.01.31.10.8
Left kidney weight2.46.912.92.53.62.62.12.62.52.3
Right kidney weight1.95.310.32.23.22.21.92.32.21.9
Tail length0.30.91.00.90.81.01.01.01.01.0
Length with tail0.00.00.2-0.10.5-0.10.20.0-0.1-0.2
Length without tail0.30.71.4-0.90.3-1.1-0.7-0.6-0.9-1.2
Liver weight, left0.00.00.1-0.1-0.30.0-0.1-0.3-0.10.0
Liver weight, right0.30.50.80.70.90.90.50.40.70.7
Parametrial fat weight0.20.41.00.51.00.60.60.60.50.4
Retroperitoneal fat weight0.51.64.31.12.11.20.91.31.11.0
Intraocular pressure2.23.13.6-1.8-1.8-1.8-1.4-1.9-1.8-1.7
Extensor digitorum longus weight3.514.017.4-3.8-3.5-4.2-3.2-3.8-3.8-3.8
Soleus weight0.41.01.51.01.20.90.91.11.01.0
Tibialis anterior weight0.20.61.20.81.10.70.50.80.80.8
Tibia length0.00.00.00.10.10.20.1-0.00.10.1
Number of licking bursts3.23.79.01.81.41.83.01.61.81.8
Food consumed during 24 hour testing period0.10.10.7-0.20.3-0.30.9-0.1-0.2-0.2
Times rat made contact with spout6.16.99.32.72.02.83.02.62.72.6
Mean time between licks in bursts7.810.915.5-3.1-3.4-3.2-3.9-3.2-3.1-3.1
Mean num. licks in bursts0.20.31.9-0.2-0.3-0.2-1.4-0.1-0.2-0.2
Std. dev. time between licks in bursts7.58.912.9-2.8-3.1-2.8-3.6-2.9-2.8-2.8
Water consumed over 24 hours3.84.58.92.01.52.03.01.92.12.0
Indifference point 0 sec0.81.23.21.01.80.90.71.31.00.7
Indifference point AUC0.20.20.9-0.2-1.0-0.2-0.3-0.4-0.2-0.1
Indifference point function ln k0.81.11.5-1.20.1-1.2-1.1-1.0-1.2-1.1
Indifference point function log k0.81.11.5-1.20.1-1.2-1.1-1.0-1.2-1.1
Delay discounting total patch changes 0 sec0.60.92.50.91.60.80.51.10.80.6
Delay discounting total patch changes 12 sec2.43.24.11.91.82.01.42.01.91.5
Delay discounting total patch changes 18 sec2.33.03.61.81.61.91.51.91.81.6
Delay discounting total patch changes 24 sec1.21.52.01.21.41.31.01.31.21.0
Delay discounting total patch changes 6 sec0.30.51.40.71.20.60.20.70.70.4
Delay discounting time to switch 0 sec2.43.74.72.01.42.01.82.22.01.9
Delay discounting water rate 0 sec2.03.23.9-1.8-1.6-2.0-1.5-2.0-1.8-1.9
Delay discounting water rate 12 sec0.20.41.00.51.00.60.50.40.50.4
Delay discounting water rate 18 sec1.41.82.6-1.4-0.8-1.4-1.1-1.6-1.5-1.5
Delay discounting water rate 24 sec0.10.20.4-0.4-0.5-0.5-0.2-0.6-0.4-0.3
Delay discounting water rate 6 sec0.30.40.6-0.70.0-0.6-0.6-0.8-0.7-0.7
Locomotor activity1.82.83.5-1.8-0.8-1.8-1.7-1.9-1.8-1.7
Locomotor testing distance4.77.79.4-2.9-1.9-3.1-2.5-3.0-2.9-2.9
Locomotor testing rearing0.40.70.9-0.9-0.4-0.9-0.8-1.0-0.9-0.9
Light reinforcement 11.52.84.1-1.7-1.4-2.0-1.3-1.6-1.7-1.9
Light reinforcement 20.81.01.4-0.9-1.2-1.0-0.9-1.2-0.9-0.8
Reaction time number correct2.53.64.71.82.21.91.71.91.91.8
Reaction time mean minus median3.54.54.9-2.1-2.2-2.2-2.0-2.0-2.1-2.1
Reaction time mean minus median AUC5.97.58.9-2.8-3.0-2.8-2.4-2.6-2.8-2.8
Reaction time num false alarms0.30.50.8-0.8-0.1-0.9-0.7-0.5-0.8-0.8
Reaction time num false alarms AUC0.10.10.2-0.40.0-0.4-0.4-0.2-0.4-0.4
Reaction time trials correct on left2.53.64.71.82.21.91.71.91.91.8
Reaction time trials on left2.23.14.41.72.11.71.61.81.71.7
Reaction time mean4.56.28.6-2.5-2.9-2.5-2.2-2.3-2.5-2.4
Reaction time mean AUC6.07.910.7-2.8-3.3-2.9-2.5-2.7-2.8-2.7
Median of all reaction times3.54.77.2-2.1-2.7-2.2-1.9-2.0-2.1-2.0
Reaction time omissions5.98.09.2-2.9-2.6-3.0-2.5-2.7-2.9-3.0
Reaction time false alarm rate0.91.31.5-1.2-0.9-1.2-1.1-1.1-1.2-1.2
Reaction time premature initiation rate0.50.71.30.90.31.10.70.40.91.0
Reaction time premature initiations1.82.63.71.71.41.91.41.31.71.8
Std. dev. reaction times6.89.410.8-3.1-3.3-3.2-2.7-3.0-3.1-3.1
Reaction time trials completed2.23.14.41.72.11.71.61.81.71.7
Reaction time trials AUC2.23.14.11.72.01.71.61.81.71.7
Social response proportion1.31.41.7-1.2-0.9-1.2-1.1-1.3-1.2-1.2
Social responses0.30.30.4-0.6-0.5-0.5-0.5-0.7-0.6-0.7
Social time0.40.50.7-0.8-0.4-0.8-0.6-0.7-0.8-0.8
Conditioned locomotion0.40.52.90.20.20.31.70.20.20.2
Cocaine response after cond. corrected1.92.13.2-1.6-1.0-1.8-1.0-1.3-1.6-1.7
Cocaine response after cond. not corrected2.83.14.4-1.9-1.2-2.1-1.4-1.7-1.9-2.0
Cocaine response before conditioning0.70.91.60.90.81.01.30.80.90.9
Saline control response0.40.61.80.51.10.51.30.50.50.4
Condit. Reinf. active minus inactive responses0.20.30.5-0.6-0.7-0.5-0.4-0.5-0.6-0.6
Condit. Reinf. active-inactive response ratio0.40.51.0-0.7-0.4-0.6-1.0-0.6-0.7-0.7
Condit. Reinf. active responses0.40.61.7-0.6-0.9-0.4-1.3-0.6-0.6-0.5
Condit. Reinf. inactive responses0.10.10.20.0-0.50.1-0.5-0.00.00.1
Condit. Reinf. lever presses3.75.18.0-2.3-1.8-2.2-2.8-2.2-2.3-2.2
Condit. Reinf. lever reinforcers received0.60.82.3-0.7-1.0-0.6-1.5-0.7-0.7-0.7
Pavlov. Cond. lever latency1.82.52.91.61.11.71.61.51.61.7
Pavlov. Cond. magazine entry latency0.20.30.40.50.30.60.60.50.50.5
Pavlov. Cond. change in total contacts0.81.11.4-1.1-0.8-1.2-0.7-1.0-1.1-1.2
Pavlov. Cond. index score0.60.81.0-1.0-0.6-0.9-1.0-0.9-1.0-1.0
Pavlov. Cond. latency score0.50.70.8-0.9-0.6-0.8-0.8-0.8-0.9-0.9
Pavlov. Cond. lever contacts1.42.02.6-1.5-0.8-1.6-1.2-1.4-1.5-1.6
Pavlov. Cond. magazine entry number0.00.10.1-0.1-0.3-0.2-0.4-0.2-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.00.10.1-0.3-0.1-0.30.3-0.2-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.71.0-0.9-0.5-0.9-0.9-0.8-0.9-1.0
Pavlov. Cond. response bias0.81.11.5-1.2-0.7-1.2-0.7-1.0-1.2-1.2
Conditioned reinforcement - actives0.40.40.5-0.6-0.7-0.7-0.4-0.5-0.6-0.6
Conditioned reinforcement - inactives0.50.61.0-0.8-0.9-0.8-0.3-1.0-0.8-0.6
Conditioned locomotion0.00.00.20.0-0.50.10.10.10.00.1
Intermittent access intake day 1-15 change1.51.52.21.21.51.21.21.21.21.0
Intermittent access intake escalation1.01.01.81.01.31.00.91.01.00.7
Intermittent access intake escalation 21.51.52.11.11.31.11.51.41.10.9
Intermitt. access day 1 inactive lever presses1.01.11.6-1.1-1.0-1.20.6-1.1-1.1-1.0
Intermitt. access day 15 inactive lever presses0.91.01.4-1.1-1.0-1.2-0.1-1.1-1.1-1.1
Intermitt. access escalation Index0.00.00.10.10.30.2-0.30.10.10.1
Intermittent access day 1 total infusions0.50.50.7-0.7-0.8-0.7-0.6-0.9-0.7-0.6
Intermittent access day 15 total infusions0.20.20.3-0.4-0.1-0.4-0.5-0.4-0.4-0.5
Intermittent access terminal intake (last 3 days)0.60.71.5-0.7-0.6-0.8-1.2-0.7-0.7-0.8
Intermittent access total infusions0.40.40.5-0.7-0.5-0.7-0.6-0.7-0.7-0.7
Intermittent access day 1 locomotion2.22.22.6-1.5-1.6-1.6-1.2-1.5-1.5-1.5
Intermittent access day 15 total locomotion0.60.60.9-0.7-1.0-0.8-0.9-0.6-0.7-0.8
Intermittent access total locomotion0.70.81.1-0.9-0.9-1.0-0.8-0.9-0.9-1.0
Intermittent access standard deviation1.01.12.70.90.80.81.61.30.90.8
Cocaine induced anxiety0.10.20.90.20.20.20.90.20.20.2
Post-drug Anxiety0.91.01.5-1.0-1.0-1.0-1.2-0.8-1.0-0.9
Baseline Anxiety1.51.64.6-1.1-1.1-1.0-2.1-1.1-1.1-1.0
Lifetime Intake0.60.60.8-0.8-0.8-0.7-0.9-0.9-0.7-0.7
Incentive Sensitization - Responses0.20.20.40.20.60.10.60.40.20.2
Incentive Sensitization - Breakpoint0.20.20.50.20.60.10.70.40.20.2
Progressive ratio test 1 active lever presses0.20.20.5-0.3-0.7-0.30.5-0.7-0.3-0.1
Progressive ratio test 1 breakpoint0.30.30.7-0.4-0.8-0.40.2-0.8-0.4-0.2
Progressive ratio test 1 inactive lever presses2.22.33.1-1.7-1.3-1.8-0.3-1.7-1.7-1.7
Progressive ratio test 2 active lever presses0.10.10.1-0.20.0-0.30.3-0.2-0.2-0.3
Progressive ratio test 2 breakpoint0.10.10.3-0.10.1-0.20.6-0.1-0.1-0.1
Progressive ratio test 2 inactive lever presses0.91.11.5-1.1-0.9-1.20.1-1.1-1.1-1.1
Total sessions with >9 infusions1.71.92.5-1.3-1.6-1.3-1.5-1.5-1.3-1.2
Short access day 1 total inactive lever presses0.00.00.20.00.20.00.5-0.00.1-0.1
Short access day 10 total inactive lever presses0.20.20.4-0.5-0.0-0.70.4-0.3-0.5-0.6
Short access day 1 total infusions0.00.10.2-0.1-0.5-0.1-0.0-0.2-0.10.1
Short access day 10 total infusions0.50.50.8-0.7-0.7-0.7-0.6-0.9-0.7-0.6
Short access total infusions0.50.61.0-0.7-1.0-0.6-0.9-0.9-0.7-0.4
Short access day 1 locomotion0.10.10.3-0.2-0.5-0.1-0.6-0.3-0.2-0.2
Short access day 10 total locomotion0.91.01.5-0.9-1.2-1.0-0.8-1.0-0.9-1.1
Short access total locomotion1.81.92.8-1.3-1.7-1.3-1.3-1.4-1.3-1.2
Compulsive drug intake1.51.52.41.11.61.01.41.31.11.0
One hour access (0.3 mA shock)0.00.00.20.10.50.10.30.20.1-0.0
One hour access (shock baseline)0.40.50.8-0.7-0.6-0.6-0.9-0.7-0.7-0.7
Number of responses in last shaping day0.20.20.80.40.20.30.90.50.40.3
Context. condit. distance diff. score8.810.714.13.23.23.33.83.13.23.1
Locomotion velocity, session 10.10.10.4-0.1-0.4-0.20.6-0.1-0.1-0.1
Locomotion distance, session 11.31.74.0-1.1-1.5-1.0-2.0-1.2-1.1-1.0
Locomotion velocity, session 20.81.01.21.10.41.11.01.01.11.0
Locomotion distance, session 21.92.75.6-1.3-1.9-1.3-2.4-1.6-1.3-1.2
Locomotion velocity, session 30.20.20.30.50.20.60.60.50.50.5
Locomotion distance, session 33.43.75.51.91.62.02.31.71.91.9
Stereotopy head waving bouts, day 30.60.70.80.80.90.90.90.80.80.8
Stereotopy head waving duration, day 30.40.50.80.60.90.70.50.70.60.7
Locomotion velocity, session 70.40.40.6-0.7-0.6-0.8-0.2-0.8-0.7-0.7
Locomotion distance, session 70.10.21.0-0.1-0.2-0.11.0-0.2-0.1-0.0
Stereotopy head waving bouts, day 70.00.00.10.20.40.2-0.20.20.20.1
Stereotopy head waving duration, day 70.40.52.3-0.5-0.2-0.6-1.5-0.3-0.5-0.6
Locomotion velocity, session 80.20.20.50.40.10.50.70.40.40.4
Locomotion distance, session 80.20.40.60.60.30.80.50.40.60.7
Degree of sensitization distance3.23.24.1-1.9-1.7-2.0-1.4-1.9-1.9-1.8
Degree of sensitization stereotypy0.10.10.2-0.2-0.1-0.2-0.5-0.1-0.2-0.2
Condit. Reinf. active minus inactive responses9.010.020.0-2.9-2.9-2.9-4.5-2.9-2.9-2.8
Condit. Reinf. active-inactive response ratio10.411.220.4-3.1-3.2-3.1-4.5-3.2-3.1-3.0
Condit. Reinf. active responses8.710.616.7-3.1-3.1-3.2-4.1-3.1-3.1-3.0
Condit. Reinf. inactive responses0.40.40.7-0.7-0.6-0.9-0.2-0.6-0.7-0.8
Incentive salience index mean8.29.927.2-2.7-2.5-2.7-5.2-2.6-2.7-2.7
Condit. Reinf. lever presses2.73.611.1-1.6-1.3-1.6-3.3-1.5-1.6-1.6
Time in familiar zone, hab. session 11.21.11.81.01.41.1-0.51.11.01.0
Time in novel zone, hab. session 10.20.21.1-0.2-0.4-0.31.1-0.2-0.2-0.2
Total zone transitions, hab. session 12.73.86.7-1.9-1.6-1.9-2.6-1.8-1.9-1.9
Total locomotion distance, hab. session 14.05.810.0-2.3-2.0-2.4-3.2-2.2-2.3-2.3
Locomotion velocity, hab. session 15.68.014.5-2.7-2.4-2.8-3.8-2.6-2.7-2.7
Time in familiar zone, hab. session 23.03.14.01.81.92.00.91.81.81.9
Time in novel zone, hab. session 21.91.92.7-1.4-1.5-1.6-0.0-1.4-1.4-1.5
Total zone transitions, hab. session 20.60.71.1-0.8-1.1-0.7-0.8-0.9-0.8-0.7
Total locomotion distance, hab. session 21.72.33.2-1.4-1.5-1.5-1.8-1.5-1.4-1.4
Locomotion velocity, hab. session 21.82.43.7-1.5-1.5-1.5-1.9-1.6-1.5-1.4
Novel to familiar place preference ratio1.31.42.8-1.1-0.9-1.2-1.7-1.0-1.1-1.2
Novelty place preference1.71.84.0-1.2-0.9-1.3-2.0-1.0-1.2-1.3
Time in novel zone, NPP test1.21.32.5-1.1-0.9-1.2-1.6-0.9-1.1-1.2
Total zone transitions, NPP test2.13.14.6-1.6-2.1-1.6-1.9-1.7-1.6-1.6
Total locomotion distance, NPP test3.04.25.4-2.0-2.3-2.0-2.1-2.0-1.9-1.9
Locomotion velocity, NPP test3.65.26.3-2.2-2.5-2.2-2.4-2.3-2.2-2.1
Pavlov. Cond. lever latency0.70.96.00.0-0.1-0.02.40.00.10.1
Pavlov. Cond. magazine entry latency0.20.31.80.20.40.2-1.30.20.20.1
Pavlov. Cond. change in total contacts0.10.10.70.20.00.2-0.80.10.20.2
Pavlov. Cond. index score0.60.71.40.71.00.8-1.20.80.70.7
Pavlov. Cond. latency score0.60.72.30.60.90.7-1.50.70.60.6
Pavlov. Cond. lever contacts0.50.63.8-0.2-0.0-0.2-1.9-0.2-0.2-0.3
Pavlov. Cond. magazine entry number0.60.71.0-0.8-1.0-0.90.9-0.8-0.8-0.8
Pavlov. Cond. intertrial magazine entries6.88.19.4-2.9-2.8-3.1-2.7-2.8-2.9-2.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.30.81.10.9-0.80.90.80.8
Pavlov. Cond. response bias0.30.31.70.30.50.3-1.30.30.30.2
Bone: apparent density12.420.623.84.54.54.64.94.44.54.4
Bone surface3.46.08.52.42.32.52.92.32.42.3
Bone volume6.210.512.73.23.23.33.63.13.23.1
Bone: connectivity density8.313.016.53.63.43.64.13.53.63.5
Bone: cortical apparent density1.62.05.61.31.11.22.41.11.31.3
Bone: cortical area0.81.22.91.01.71.20.71.01.00.9
Bone: cortical porosity3.74.09.4-1.8-1.8-1.8-3.1-1.8-1.8-1.7
Bone: cortical porosity2.52.76.8-1.4-1.6-1.4-2.6-1.4-1.4-1.4
Bone: cortical thickness1.01.63.01.21.71.31.11.21.21.2
Bone: cortical thickness1.01.21.91.11.41.10.91.01.11.1
Bone: cortical tissue density1.72.26.31.31.11.22.51.11.31.3
Bone: elastic displacement0.20.21.10.3-0.10.4-1.10.30.30.3
Bone: elastic work0.40.52.80.4-0.10.6-1.70.40.40.3
Bone: endosteal estimation0.00.00.0-0.00.10.2-0.0-0.0-0.0-0.1
Bone: endosteal perimeter0.40.81.40.81.21.00.90.80.80.7
Bone: final force1.01.73.41.31.91.50.41.21.31.2
Bone: final moment1.11.93.41.41.81.60.31.31.41.3
Bone: marrow area0.00.00.10.00.20.30.00.00.0-0.0
Bone: maximum diameter2.24.16.91.82.22.02.61.81.81.8
Bone: maximum force0.20.40.80.50.90.7-0.70.40.50.5
Bone: maximum moment0.30.40.70.60.80.8-0.70.50.60.6
Bone: minimum diameter0.00.10.2-0.20.30.0-0.4-0.3-0.2-0.3
Bone: periosteal estimation0.10.30.80.40.90.70.30.40.40.4
Bone: periosteal perimeter1.11.82.81.21.71.51.11.31.21.2
Bone: post-yield work1.72.35.2-1.4-1.3-1.3-2.3-1.4-1.4-1.3
Bone: stiffness0.20.20.80.20.90.4-0.70.10.20.3
Bone: tissue strength0.40.40.9-0.5-1.0-0.5-0.7-0.5-0.5-0.5
Bone: trabecular number15.824.630.84.94.94.95.54.84.94.8
Bone: trabecular spacing7.69.818.0-2.9-3.0-2.9-4.2-2.9-2.9-2.8
Bone: trabecular thickness13.716.631.23.83.73.95.63.73.83.7
Bone: trabecular tissue density1.01.43.8-1.0-0.9-1.1-2.0-1.0-1.0-1.0
Breakpoint value in progressive ratio session0.40.50.7-0.6-0.7-0.6-0.8-0.8-0.7-0.7
Distance traveled before self-admin0.60.61.10.80.81.0-0.30.80.80.8
Distance traveled after self-admin0.40.40.9-0.6-0.6-0.5-0.9-0.6-0.6-0.6
Delta time in closed arm before/after self-admin2.52.43.11.61.71.81.21.41.51.6
Delta time in open arm before/after self-admin0.30.31.1-0.5-0.5-0.4-1.0-0.4-0.5-0.4
Diff in mean of infusions in LGA sessions2.73.05.4-1.6-2.3-1.8-1.7-1.6-1.6-1.4
Extinction: sum of active levers before priming4.44.46.7-2.0-2.2-2.0-2.6-2.0-2.0-2.0
Active lever presses in extinction session 61.21.21.9-1.1-1.0-1.4-0.4-1.2-1.1-1.3
Delta distance traveled before/after self-admin1.51.61.7-1.3-1.2-1.3-1.2-1.3-1.2-1.3
Delta ambulatory time before/after self-admin0.80.91.0-0.9-0.9-0.9-1.0-0.9-0.9-0.9
Time in closed arm before self-admin0.00.10.2-0.2-0.0-0.1-0.4-0.1-0.2-0.4
Time in closed arm after self-admin0.40.40.70.60.80.80.50.70.60.4
Time in open arm before self-admin0.40.40.9-0.6-1.0-0.7-0.7-0.5-0.6-0.3
Time in open arm after self-admin0.10.10.5-0.2-0.3-0.2-0.7-0.2-0.2-0.0
Sum of active levers in priming session hrs 5-60.70.71.2-0.8-0.6-1.10.8-0.9-0.8-0.9
Time to tail flick, vehicle, before self-admin0.10.10.50.20.70.10.50.30.2-0.0
Time to tail flick, vehicle, after self-admin4.34.610.0-2.0-2.0-1.7-3.2-1.9-2.0-1.9
Time to tail flick, test, before self-admin3.33.34.2-2.0-1.3-2.0-1.3-1.9-1.9-2.0
Time to tail flick, test, after self-admin0.91.01.8-0.9-0.6-0.7-1.4-1.0-0.9-1.1
Delta time to tail flick, vehicle, before/after SA1.11.13.2-0.9-1.1-0.7-1.8-0.9-0.9-0.8
Delta time to tail flick, test, before/after SA1.41.31.61.20.81.31.11.21.21.1
Ambulatory time before self-admin0.20.20.30.40.40.50.40.50.40.4
Ambulatory time after self-admin0.00.00.00.10.10.0-0.20.00.10.0
Total heroin consumption0.60.71.1-0.8-1.0-0.9-0.2-1.0-0.8-1.0
Area under the delay curve0.10.10.4-0.1-0.1-0.1-0.6-0.1-0.1-0.0
Delay disc. indifference point, 0s delay0.91.03.0-0.9-0.3-0.9-1.7-0.9-0.9-0.8
Delay disc. indifference point, 16s delay0.20.20.3-0.6-0.5-0.6-0.0-0.5-0.6-0.5
Delay disc. indifference point, 2s delay0.10.20.50.30.70.3-0.20.20.30.5
Delay disc. indifference point, 24s delay0.10.10.60.30.10.30.80.20.30.2
Delay disc. indifference point, 4s delay0.60.71.10.81.10.8-0.20.90.80.8
Delay disc. indifference point, 8s delay0.50.51.5-0.5-0.9-0.5-1.2-0.5-0.5-0.6
Delay discount exponential model param0.00.00.10.00.00.00.3-0.00.0-0.1
Delay discount hyperbolic model param0.00.00.30.1-0.00.10.50.00.1-0.0
Fecal boli incidents, locomotor time 10.80.81.2-0.8-1.0-0.8-1.1-0.8-0.8-1.0
Change in fecal boli incidents, locomotor task2.62.54.71.42.21.31.91.41.41.4
Time >=10cm from walls, locomotor time 11.41.42.01.21.01.31.11.41.21.1
Bouts of movement, locomotor time 11.31.41.91.31.01.40.81.11.31.4
Total resting periods, locomotor time 12.42.73.31.71.61.81.31.61.71.8
Rest time, locomotor task time 11.21.31.81.21.31.30.21.11.21.3
Distance moved, locomotor task time 10.50.61.0-0.7-1.0-1.0-0.2-0.4-0.7-0.9
Vertical activity count, locomotor time 10.70.71.2-0.8-0.8-1.1-0.8-0.5-0.8-0.9
Time >=10cm from walls, locomotor time 20.30.30.40.50.60.6-0.40.50.50.6
Bouts of movement, locomotor time 20.80.82.80.61.10.71.70.50.60.7
Total resting periods, locomotor time 21.21.23.50.81.30.91.90.70.80.9
Rest time, locomotor task time 20.80.91.31.01.11.00.30.90.91.1
Distance moved, locomotor task time 20.00.10.3-0.1-0.5-0.10.10.1-0.0-0.2
Vertical activity count, locomotor time 20.20.20.30.50.60.40.00.50.50.3
Weight adjusted by age0.30.31.40.40.30.31.20.40.40.4
Seeking ratio, delayed vs. immediate footshock1.61.84.91.11.21.12.21.01.11.1
Locomotion in novel chamber0.30.40.7-0.7-0.8-0.7-0.1-0.7-0.7-0.6
Locomotion in novel chamber post-restriction0.20.20.5-0.3-0.3-0.40.7-0.5-0.3-0.2
Progressive ratio1.01.23.20.91.01.21.80.50.91.0
Food seeking constrained by brief footshock0.50.61.0-0.6-0.8-0.5-1.0-1.0-0.7-0.6
Seeking ratio, punishment vs. effort3.64.48.1-1.9-2.0-2.1-2.8-1.7-1.9-2.0
Run reversals in cocaine runway, females0.20.20.3-0.4-0.6-0.20.5-0.6-0.4-0.1
Run reversals in cocaine runway, males2.22.12.6-1.5-1.6-1.5-1.0-1.5-1.5-1.4
Latency to leave start box in cocaine runway0.91.01.60.91.00.91.30.90.91.0
Latency to leave start box in cocaine runway, F2.22.43.11.51.81.61.51.41.51.6
Latency to leave start box in cocaine runway, M0.70.71.2-0.8-1.1-1.0-0.1-0.7-0.8-0.8
Cd content in liver0.00.00.1-0.0-0.30.00.2-0.1-0.0-0.0
Co content in liver4.65.48.3-2.2-2.1-2.4-2.9-2.2-2.2-2.2
Cu content in liver0.20.30.6-0.50.3-0.5-0.8-0.3-0.5-0.6
Fe content in liver3.94.67.22.02.12.12.72.02.02.0
K content in liver1.01.01.5-1.0-0.6-1.0-1.2-0.9-1.0-1.1
Mg content in liver0.80.81.1-1.0-0.7-1.0-0.8-0.9-1.0-1.0
Mn content in liver1.11.32.21.01.51.11.01.21.01.0
Na content in liver0.50.50.80.70.60.8-0.90.60.70.7
Rb content in liver0.81.01.6-1.1-0.9-1.2-0.2-1.0-1.1-1.1
Se content in liver2.73.28.11.61.41.62.81.51.61.6
Sr content in liver0.90.91.10.90.91.00.90.90.90.9
Zn content in liver0.00.00.1-0.00.1-0.0-0.30.0-0.0-0.1