Hub : Genes

Ugt2b15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	ENSRNOG00000064466	0.36	0.18	0.0e+00	0.16	0.11	0.14	0.09	9.0e-18	3.1e-12	9.5e-15	3.8e-10
2	Liver	intron excision ratio	chr14:20718303:20719756	0.56	0.12	0.0e+00	0.51	0.47	0.53	0.53	4.5e-66	3.6e-58	2.4e-68	9.0e-70
3	Liver	intron excision ratio	chr14:20718303:20770242	0.82	0.05	0.0e+00	0.57	0.5	0.62	0.62	8.6e-77	4.7e-63	1.7e-87	1.3e-88
4	Liver	intron excision ratio	chr14:20721564:20733031	0.85	0.05	0.0e+00	0.5	0.34	0.51	0.5	6.8e-64	1.1e-39	4.3e-65	7.4e-63
5	Liver	intron excision ratio	chr14:20721564:20757388	0.75	0.1	0.0e+00	0.55	0.42	0.56	0.56	1.8e-72	4.3e-50	6.3e-75	5.1e-74
6	Liver	intron excision ratio	chr14:20721564:20779363	0.16	0.09	4.4e-15	0.12	0.12	0.12	0.13	5.8e-13	7.4e-13	1.5e-13	7.1e-14
7	Liver	intron excision ratio	chr14:20768768:20770242	0.18	0.09	0.0e+00	0.14	0.12	0.14	0.14	7.3e-15	1.1e-13	3.2e-15	9.0e-16
8	Liver	intron excision ratio	chr14:20768768:20819532	0.03	0.03	6.1e-03	0.01	0	-0	0	3.6e-02	7.2e-02	5.1e-01	2.0e-01
9	Liver	intron excision ratio	chr14:20771925:20779363	0.89	0	0.0e+00	0.57	0.5	0.62	0.64	2.3e-77	3.7e-63	1.1e-88	3.1e-92
10	Liver	intron excision ratio	chr14:20818050:20819532	0.57	0.14	0.0e+00	0.44	0.41	0.5	0.51	8.4e-54	4.0e-49	1.6e-64	4.8e-65
11	Liver	intron excision ratio	chr14:20820793:20828959	0.88	0.01	0.0e+00	0.62	0.54	0.69	0.7	6.3e-88	4.5e-72	4.8e-106	1.4e-107
12	Liver	mRNA stability	ENSRNOG00000064466	0.59	0.26	0.0e+00	0.1	0.18	0.18	0.2	6.2e-11	3.8e-20	3.4e-19	6.6e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
BMI with tail	1.7	5.6	8.4	-1.6	2.3	2.6	1.9	2.3	2.7	-2.2	-1.3	-2.7	-2.7	-2.8	2.9
BMI without tail	0.2	0.5	2.4	0.4	0.4	0.7	0.3	0.4	0.9	0.0	0.4	-0.8	-0.5	-0.9	1.5
Body weight	0.2	0.8	2.4	-0.1	0.8	1.0	0.5	0.8	1.0	-0.5	-0.2	-1.1	-1.1	-1.2	1.6
Epididymis fat weight	0.1	0.2	0.9	-0.0	0.4	0.6	0.3	0.4	0.4	-0.1	0.1	-0.6	-0.5	-0.6	1.0
Glucose	1.0	1.5	2.0	1.2	-1.4	-1.3	-1.0	-1.3	-1.4	1.2	1.1	1.3	1.3	1.2	-1.1
Heart weight	0.3	0.5	1.0	-0.8	0.7	0.7	0.7	0.7	0.3	-0.7	-1.0	-0.7	-0.5	-0.6	0.3
Left kidney weight	0.3	0.7	1.6	0.3	-0.7	-0.8	-0.6	-0.8	-1.0	0.9	0.2	0.9	1.3	1.0	-1.1
Right kidney weight	0.3	0.9	1.5	1.0	-1.0	-0.9	-0.7	-0.9	-1.2	1.2	0.9	0.9	1.1	0.9	-0.5
Tail length	0.1	0.2	0.7	0.5	-0.3	-0.4	-0.4	-0.5	-0.3	0.6	0.1	0.4	0.8	0.6	-0.5
Length with tail	0.7	2.5	3.2	1.5	-1.6	-1.6	-1.6	-1.6	-1.8	1.8	1.1	1.6	1.7	1.7	-1.4
Length without tail	0.4	1.0	1.6	0.9	-1.1	-1.1	-1.0	-0.9	-1.3	1.0	1.0	1.0	0.7	0.9	-0.8
Liver weight, left	1.3	2.0	3.1	1.8	-1.7	-1.5	-1.3	-1.6	-1.2	1.6	1.7	1.4	1.2	1.2	-0.4
Liver weight, right	2.3	3.8	5.1	2.3	-2.2	-2.0	-1.8	-2.1	-2.0	2.1	2.2	2.0	1.7	1.8	-1.2
Parametrial fat weight	1.6	3.1	5.6	2.4	-2.0	-1.7	-2.0	-1.8	-1.8	1.8	2.2	1.7	1.3	1.4	-0.7
Retroperitoneal fat weight	0.2	0.6	2.0	1.4	-0.6	-0.2	-0.5	-0.5	-0.3	1.0	1.3	0.1	0.0	-0.0	1.0
Intraocular pressure	0.6	0.9	1.3	-0.4	0.9	0.9	0.7	1.0	1.0	-0.9	-0.8	-1.0	-1.1	-1.0	1.1
Extensor digitorum longus weight	10.4	41.6	47.4	-6.6	6.8	6.6	6.4	6.7	6.6	-6.9	-6.6	-6.5	-6.4	-6.3	4.8
Soleus weight	0.2	0.5	2.0	-1.4	0.7	0.5	0.6	0.6	0.4	-0.9	-1.2	-0.3	-0.3	-0.1	-0.6
Tibialis anterior weight	4.2	14.6	16.4	-3.5	3.9	3.9	3.7	4.0	4.0	-3.8	-3.5	-4.0	-3.9	-3.9	3.4
Tibia length	0.1	0.3	0.6	0.6	-0.5	-0.4	-0.5	-0.5	-0.7	0.8	0.8	0.4	0.6	0.4	-0.2
Number of licking bursts	0.1	0.2	0.3	-0.4	0.4	0.4	0.5	0.4	0.5	-0.4	-0.6	-0.4	-0.3	-0.3	0.3
Food consumed during 24 hour testing period	2.5	3.0	4.4	0.9	-1.6	-1.7	-1.7	-1.9	-1.8	1.6	0.5	1.9	2.1	2.1	-2.1
Times rat made contact with spout	0.1	0.1	0.5	0.7	-0.4	-0.3	-0.5	-0.5	0.1	0.6	0.2	0.2	0.2	0.3	0.3
Mean time between licks in bursts	4.6	6.4	7.9	-2.2	2.5	2.5	2.6	2.8	2.5	-2.7	-2.1	-2.7	-2.6	-2.7	2.3
Mean num. licks in bursts	0.6	0.7	1.2	1.1	-0.9	-0.8	-1.0	-0.9	-0.5	1.1	0.9	0.7	0.7	0.7	-0.2
Std. dev. time between licks in bursts	0.9	1.1	2.0	-1.0	1.0	0.9	1.3	1.2	0.7	-1.3	-1.4	-0.8	-1.0	-0.9	0.3
Water consumed over 24 hours	1.7	2.0	2.6	1.2	-1.4	-1.4	-1.5	-1.6	-1.4	1.5	1.0	1.5	1.5	1.5	-1.2
Indifference point 0 sec	0.4	0.7	1.6	1.0	-0.8	-0.8	-0.6	-0.7	-1.3	0.6	1.2	0.8	0.6	0.7	-0.8
Indifference point AUC	1.8	2.1	4.4	2.1	-1.5	-1.3	-1.5	-1.7	-0.7	1.9	1.9	1.2	1.3	1.3	-0.1
Indifference point function ln k	0.6	0.8	1.5	-1.2	1.0	0.9	0.9	1.0	0.3	-1.2	-1.0	-0.7	-0.8	-0.8	-0.0
Indifference point function log k	0.6	0.8	1.5	-1.2	1.0	0.9	0.9	1.0	0.3	-1.2	-1.0	-0.7	-0.8	-0.8	-0.0
Delay discounting total patch changes 0 sec	0.4	0.7	1.5	1.0	-0.8	-0.8	-0.6	-0.7	-1.2	0.6	1.2	0.8	0.6	0.6	-0.7
Delay discounting total patch changes 12 sec	0.2	0.3	1.1	1.0	-0.5	-0.2	-0.1	-0.4	-0.2	0.5	1.0	0.1	0.3	0.1	0.4
Delay discounting total patch changes 18 sec	0.1	0.1	0.6	0.8	-0.2	-0.2	-0.3	-0.3	0.2	0.3	0.7	0.1	-0.0	0.2	0.4
Delay discounting total patch changes 24 sec	0.6	0.7	1.3	0.9	-0.9	-0.9	-0.9	-1.1	-0.4	1.1	0.7	0.8	0.9	1.0	-0.4
Delay discounting total patch changes 6 sec	0.9	1.4	2.2	1.5	-1.3	-1.1	-1.2	-1.3	-1.2	1.3	1.4	1.1	1.1	1.1	-0.6
Delay discounting time to switch 0 sec	3.2	4.9	6.2	-2.0	2.3	2.3	2.1	2.4	2.0	-2.5	-1.9	-2.3	-2.5	-2.4	1.8
Delay discounting water rate 0 sec	1.3	2.1	3.2	1.2	-1.5	-1.5	-1.2	-1.5	-1.6	1.6	1.3	1.4	1.8	1.5	-1.2
Delay discounting water rate 12 sec	0.5	0.8	1.7	-0.0	-0.8	-0.9	-0.9	-0.9	-1.0	0.7	0.1	1.0	1.2	1.1	-1.3
Delay discounting water rate 18 sec	2.3	3.1	5.1	0.8	-1.7	-1.8	-1.5	-1.7	-2.2	1.5	1.1	1.9	2.1	1.9	-2.2
Delay discounting water rate 24 sec	1.5	2.1	5.2	0.3	-1.2	-1.4	-1.1	-1.4	-1.8	1.0	0.4	1.6	1.9	1.7	-2.3
Delay discounting water rate 6 sec	0.6	0.9	1.5	0.5	-0.9	-0.9	-1.0	-1.0	-0.9	1.2	0.8	0.9	1.1	1.0	-0.7
Locomotor activity	0.6	1.0	2.8	0.1	-0.8	-0.9	-0.6	-0.9	-1.4	0.7	-0.0	1.1	1.2	1.2	-1.7
Locomotor testing distance	0.5	0.8	4.0	-0.4	-0.4	-0.6	-0.3	-0.5	-1.3	0.1	-0.4	0.9	1.1	1.0	-2.0
Locomotor testing rearing	0.3	0.4	2.2	-0.6	0.0	-0.2	0.1	-0.2	-0.8	-0.2	-0.7	0.4	0.8	0.5	-1.5
Light reinforcement 1	0.4	0.8	1.3	1.1	-0.9	-0.8	-0.8	-1.0	-0.7	1.1	1.1	0.8	0.9	0.9	-0.5
Light reinforcement 2	0.1	0.1	0.2	0.0	0.2	0.1	0.3	0.3	0.5	-0.2	-0.3	-0.2	-0.3	-0.2	0.4
Reaction time number correct	0.2	0.2	0.8	-0.6	0.6	0.5	0.4	0.2	0.8	-0.2	-0.9	-0.4	-0.0	-0.2	0.3
Reaction time mean minus median	0.5	0.7	1.4	-0.3	0.7	0.9	0.6	0.9	0.7	-0.8	-0.1	-0.9	-1.1	-1.1	1.2
Reaction time mean minus median AUC	0.8	1.0	3.2	0.0	0.8	1.0	0.6	0.9	1.1	-0.7	0.0	-1.1	-1.2	-1.3	1.8
Reaction time num false alarms	0.2	0.3	1.1	0.8	-0.2	-0.0	-0.3	-0.2	0.3	0.6	1.0	-0.1	-0.1	-0.1	0.9
Reaction time num false alarms AUC	0.2	0.3	1.4	0.4	0.1	0.3	0.1	0.2	0.6	0.2	0.7	-0.4	-0.5	-0.5	1.2
Reaction time trials correct on left	0.2	0.2	0.8	-0.6	0.6	0.5	0.4	0.2	0.8	-0.2	-0.9	-0.4	-0.0	-0.2	0.3
Reaction time trials on left	0.2	0.3	0.9	-0.7	0.6	0.5	0.4	0.2	0.9	-0.3	-0.9	-0.5	-0.1	-0.2	0.3
Reaction time mean	0.6	0.8	1.4	-0.4	0.8	0.9	0.6	1.0	0.8	-0.9	-0.2	-1.0	-1.1	-1.1	1.2
Reaction time mean AUC	0.5	0.6	1.3	-0.2	0.7	0.8	0.5	0.9	0.7	-0.8	0.0	-0.9	-1.0	-1.1	1.1
Median of all reaction times	0.5	0.7	1.2	-0.4	0.8	0.9	0.6	0.9	0.9	-0.9	-0.2	-0.9	-1.0	-1.1	1.1
Reaction time omissions	1.7	2.3	3.0	-1.6	1.6	1.6	1.3	1.5	1.7	-1.4	-1.7	-1.6	-1.4	-1.5	1.4
Reaction time false alarm rate	0.2	0.3	1.1	0.7	-0.2	0.0	-0.1	0.1	0.1	0.4	1.1	-0.1	-0.5	-0.3	0.9
Reaction time premature initiation rate	0.1	0.2	0.6	0.8	-0.3	-0.2	-0.5	-0.4	-0.3	0.5	0.8	0.2	0.4	0.2	0.1
Reaction time premature initiations	0.1	0.1	0.4	0.6	-0.1	-0.1	-0.4	-0.4	0.1	0.5	0.5	0.0	0.4	0.1	0.3
Std. dev. reaction times	0.4	0.5	1.0	-0.3	0.6	0.7	0.4	0.8	0.5	-0.7	-0.0	-0.8	-0.9	-1.0	1.0
Reaction time trials completed	0.2	0.3	0.9	-0.7	0.6	0.5	0.4	0.2	0.9	-0.3	-0.9	-0.5	-0.1	-0.2	0.3
Reaction time trials AUC	0.3	0.4	1.0	-0.7	0.7	0.6	0.5	0.3	1.0	-0.3	-0.9	-0.6	-0.2	-0.4	0.5
Social response proportion	1.1	1.2	2.0	1.4	-1.2	-1.1	-1.2	-1.3	-0.4	1.4	1.3	1.0	0.7	0.9	0.1
Social responses	0.2	0.3	0.6	0.6	-0.6	-0.5	-0.5	-0.8	-0.2	0.8	0.6	0.4	0.6	0.5	0.0
Social time	0.7	0.9	1.7	1.2	-1.0	-0.9	-1.0	-1.0	-0.7	1.1	1.3	0.8	0.8	0.8	-0.3
Conditioned locomotion	0.6	0.7	1.6	-1.3	1.0	0.9	0.8	0.7	0.8	-0.9	-1.2	-0.8	-0.5	-0.6	0.3
Cocaine response after cond. corrected	0.7	0.8	1.0	0.9	-0.8	-0.9	-1.0	-0.9	-0.7	1.0	0.8	0.9	0.9	1.0	-0.6
Cocaine response after cond. not corrected	0.8	0.9	1.2	0.8	-0.9	-1.0	-1.0	-1.0	-0.9	0.9	0.7	1.0	1.1	1.1	-1.0
Cocaine response before conditioning	0.1	0.1	0.2	-0.5	0.3	0.2	0.1	0.2	-0.1	-0.4	-0.4	-0.1	0.0	-0.1	-0.4
Saline control response	0.8	1.0	1.2	0.8	-1.1	-1.1	-1.1	-1.0	-1.0	1.0	0.8	1.1	1.1	1.1	-0.9
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	0.4	-0.3	-0.2	-0.2	-0.2	-0.5	0.2	0.4	0.3	0.2	0.1	-0.2
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.5	-0.3	-0.3	-0.5	-0.4	-0.4	0.4	0.5	0.3	0.3	0.3	-0.1
Condit. Reinf. active responses	0.2	0.2	0.6	0.4	-0.5	-0.4	-0.3	-0.4	-0.8	0.3	0.4	0.5	0.5	0.4	-0.6
Condit. Reinf. inactive responses	0.5	0.6	1.4	0.5	-0.8	-0.9	-0.5	-0.7	-1.0	0.6	0.5	0.9	0.9	0.8	-1.2
Condit. Reinf. lever presses	0.6	0.9	2.0	0.3	-0.8	-0.9	-0.9	-0.9	-1.1	0.7	0.3	1.0	1.2	1.1	-1.4
Condit. Reinf. lever reinforcers received	0.3	0.4	0.9	0.3	-0.5	-0.5	-0.4	-0.5	-0.9	0.4	0.3	0.7	0.7	0.6	-0.9
Pavlov. Cond. lever latency	0.1	0.2	0.6	0.8	-0.2	-0.0	-0.1	-0.1	0.2	0.3	0.8	-0.1	-0.2	-0.2	0.8
Pavlov. Cond. magazine entry latency	0.6	0.7	1.9	-1.4	0.9	0.7	0.7	0.9	0.4	-1.0	-1.2	-0.6	-0.5	-0.5	-0.2
Pavlov. Cond. change in total contacts	0.3	0.5	1.7	-1.3	0.7	0.4	0.5	0.5	0.1	-0.7	-1.3	-0.2	-0.1	-0.1	-0.7
Pavlov. Cond. index score	0.4	0.6	2.1	-1.4	0.7	0.5	0.6	0.6	0.2	-0.9	-1.4	-0.3	-0.2	-0.2	-0.7
Pavlov. Cond. latency score	0.7	0.9	2.9	-1.7	1.0	0.7	0.7	0.8	0.4	-1.0	-1.7	-0.5	-0.3	-0.3	-0.6
Pavlov. Cond. lever contacts	0.2	0.2	1.2	-0.7	0.0	-0.2	-0.1	-0.1	-0.4	-0.2	-0.7	0.3	0.4	0.4	-1.1
Pavlov. Cond. magazine entry number	1.0	1.3	3.5	1.9	-1.2	-1.0	-1.0	-1.2	-0.6	1.4	1.6	0.8	0.6	0.7	0.3
Pavlov. Cond. intertrial magazine entries	1.5	2.0	4.5	2.1	-1.6	-1.4	-1.3	-1.4	-1.1	1.6	1.9	1.2	1.0	1.0	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.8	-1.3	0.7	0.4	0.5	0.6	0.1	-0.8	-1.3	-0.2	-0.1	-0.1	-0.8
Pavlov. Cond. response bias	0.4	0.5	1.8	-1.3	0.6	0.4	0.5	0.5	0.1	-0.8	-1.3	-0.2	-0.1	-0.1	-0.8
Conditioned reinforcement - actives	0.2	0.2	0.7	-0.8	0.5	0.4	0.4	0.4	0.3	-0.5	-0.8	-0.3	0.0	-0.1	-0.2
Conditioned reinforcement - inactives	1.2	1.3	2.1	0.8	-1.1	-1.2	-1.4	-1.3	-1.1	1.1	0.9	1.2	1.3	1.3	-1.1
Conditioned locomotion	0.0	0.0	0.2	-0.2	0.0	-0.1	-0.2	-0.1	-0.1	0.1	-0.2	0.1	0.2	0.3	-0.4
Intermittent access intake day 1-15 change	1.3	1.3	3.4	-1.8	1.4	1.3	1.1	1.0	0.8	-0.9	-1.8	-1.1	-0.5	-0.8	0.0
Intermittent access intake escalation	0.6	0.6	2.0	-1.3	1.0	0.8	0.7	0.5	0.4	-0.5	-1.4	-0.6	-0.2	-0.4	-0.3
Intermittent access intake escalation 2	0.1	0.1	0.3	-0.2	0.1	-0.0	0.0	-0.3	-0.3	0.2	-0.2	0.2	0.5	0.4	-0.6
Intermitt. access day 1 inactive lever presses	1.0	1.1	1.4	1.1	-0.9	-1.0	-1.1	-1.2	-1.0	0.9	1.1	1.0	1.0	1.0	-1.0
Intermitt. access day 15 inactive lever presses	1.4	1.5	2.1	1.0	-1.2	-1.2	-1.3	-1.4	-1.4	1.2	0.6	1.3	1.4	1.4	-1.3
Intermitt. access escalation Index	1.0	0.9	1.7	-1.3	1.0	0.9	0.8	0.9	0.9	-1.1	-1.3	-0.8	-0.9	-0.7	0.4
Intermittent access day 1 total infusions	0.0	0.0	0.1	-0.3	-0.2	-0.2	-0.2	-0.1	-0.1	-0.0	-0.3	0.2	0.1	0.2	-0.3
Intermittent access day 15 total infusions	0.2	0.2	0.6	-0.7	0.2	0.0	-0.1	-0.2	-0.2	0.1	-0.8	0.1	0.4	0.3	-0.8
Intermittent access terminal intake (last 3 days)	0.3	0.3	1.0	-0.2	-0.2	-0.3	-0.3	-0.6	-0.6	0.5	-0.2	0.4	0.8	0.6	-1.0
Intermittent access total infusions	0.0	0.1	0.2	-0.3	0.0	-0.1	-0.1	-0.2	-0.2	0.1	-0.3	0.1	0.3	0.2	-0.5
Intermittent access day 1 locomotion	0.0	0.0	0.1	-0.0	-0.3	-0.3	-0.2	-0.1	-0.2	0.1	0.0	0.3	0.1	0.3	-0.3
Intermittent access day 15 total locomotion	0.0	0.0	0.2	-0.3	0.0	-0.0	-0.0	-0.0	-0.2	-0.1	-0.3	0.1	0.2	0.2	-0.4
Intermittent access total locomotion	0.1	0.1	0.2	-0.4	0.3	0.3	0.3	0.3	0.2	-0.4	-0.4	-0.3	-0.3	-0.3	0.2
Intermittent access standard deviation	0.2	0.2	0.7	0.0	-0.3	-0.3	-0.4	-0.5	-0.6	0.5	-0.0	0.4	0.7	0.6	-0.8
Cocaine induced anxiety	0.1	0.1	0.1	-0.2	0.3	0.3	0.2	0.2	0.3	-0.2	-0.0	-0.3	-0.3	-0.3	0.3
Post-drug Anxiety	0.1	0.1	0.7	0.5	-0.1	0.1	-0.1	-0.0	0.3	0.2	0.6	-0.2	-0.2	-0.3	0.8
Baseline Anxiety	0.1	0.1	0.3	0.1	-0.3	-0.4	-0.4	-0.4	-0.3	0.2	-0.0	0.4	0.4	0.4	-0.5
Lifetime Intake	0.0	0.0	0.2	-0.4	0.2	0.1	-0.1	-0.0	0.1	-0.2	-0.4	-0.1	0.0	0.0	-0.2
Incentive Sensitization - Responses	0.1	0.1	0.1	-0.3	0.3	0.3	0.3	0.2	0.2	-0.3	-0.1	-0.3	-0.1	-0.2	0.2
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	-0.3	0.2	0.2	0.3	0.1	0.1	-0.2	-0.1	-0.2	0.0	-0.1	0.0
Progressive ratio test 1 active lever presses	0.1	0.1	0.2	-0.4	0.2	0.2	0.1	0.2	0.3	-0.1	-0.5	-0.2	-0.1	-0.1	0.2
Progressive ratio test 1 breakpoint	0.1	0.1	0.4	-0.5	0.3	0.3	0.2	0.3	0.4	-0.3	-0.6	-0.3	-0.1	-0.2	0.2
Progressive ratio test 1 inactive lever presses	2.3	2.5	3.2	1.7	-1.6	-1.5	-1.8	-1.7	-1.5	1.6	1.6	1.6	1.5	1.5	-1.2
Progressive ratio test 2 active lever presses	0.0	0.0	0.0	-0.0	-0.0	0.0	-0.2	-0.2	0.0	0.1	0.1	0.0	0.2	0.1	-0.0
Progressive ratio test 2 breakpoint	0.0	0.0	0.0	-0.0	0.1	0.1	-0.1	-0.0	0.1	0.0	0.1	-0.1	0.2	-0.0	0.1
Progressive ratio test 2 inactive lever presses	0.9	1.0	1.6	0.6	-0.9	-1.0	-1.3	-1.2	-0.9	1.1	0.5	1.1	1.2	1.2	-1.0
Total sessions with >9 infusions	1.6	1.8	3.7	-1.9	1.4	1.3	1.2	1.2	1.1	-1.6	-1.8	-1.1	-1.2	-1.0	0.4
Short access day 1 total inactive lever presses	1.4	1.6	3.3	0.4	-1.0	-1.2	-1.2	-1.4	-1.4	1.1	0.3	1.3	1.5	1.5	-1.8
Short access day 10 total inactive lever presses	1.5	1.6	2.8	0.9	-1.1	-1.3	-1.3	-1.4	-1.4	1.0	0.8	1.3	1.4	1.4	-1.7
Short access day 1 total infusions	0.1	0.1	0.3	0.2	-0.4	-0.4	-0.5	-0.4	-0.2	0.4	0.1	0.3	0.2	0.3	-0.2
Short access day 10 total infusions	0.0	0.0	0.1	-0.1	0.3	0.2	-0.2	0.0	0.3	-0.2	-0.1	-0.1	-0.3	-0.1	-0.1
Short access total infusions	0.3	0.3	0.5	-0.6	0.6	0.6	0.2	0.4	0.7	-0.6	-0.7	-0.5	-0.6	-0.5	0.3
Short access day 1 locomotion	0.0	0.0	0.0	-0.1	0.2	0.2	0.1	0.2	0.1	-0.2	0.1	-0.1	-0.2	-0.1	0.0
Short access day 10 total locomotion	0.3	0.3	0.7	-0.2	0.4	0.5	0.4	0.5	0.6	-0.4	-0.3	-0.6	-0.8	-0.6	0.8
Short access total locomotion	0.5	0.5	0.6	-0.7	0.7	0.7	0.5	0.6	0.8	-0.6	-0.8	-0.7	-0.8	-0.7	0.6
Compulsive drug intake	0.3	0.3	0.8	0.9	-0.6	-0.6	-0.7	-0.3	0.0	0.3	0.9	0.4	-0.1	0.2	0.3
One hour access (0.3 mA shock)	0.1	0.2	0.4	0.1	-0.3	-0.4	-0.5	-0.5	-0.4	0.2	0.1	0.4	0.4	0.5	-0.7
One hour access (shock baseline)	0.0	0.0	0.2	-0.3	0.3	0.3	0.1	-0.1	0.0	0.1	-0.4	-0.2	0.1	-0.0	-0.2
Number of responses in last shaping day	0.4	0.4	0.6	-0.5	0.7	0.7	0.4	0.7	0.8	-0.8	-0.4	-0.7	-0.7	-0.7	0.7
Context. condit. distance diff. score	0.6	0.8	2.9	-0.3	-0.5	-0.8	-0.7	-0.7	-1.0	0.3	-0.3	0.9	1.1	1.1	-1.7
Locomotion velocity, session 1	1.2	1.2	3.0	-0.5	1.0	1.1	1.0	1.1	1.3	-0.8	-0.2	-1.2	-1.4	-1.3	1.7
Locomotion distance, session 1	0.3	0.4	0.5	0.4	-0.5	-0.6	-0.6	-0.6	-0.7	0.6	0.3	0.7	0.6	0.7	-0.7
Locomotion velocity, session 2	0.2	0.3	0.6	0.4	-0.4	-0.4	-0.4	-0.4	-0.8	0.3	0.4	0.5	0.5	0.5	-0.8
Locomotion distance, session 2	0.1	0.2	0.2	0.4	-0.4	-0.4	-0.3	-0.4	-0.5	0.5	0.2	0.5	0.5	0.5	-0.5
Locomotion velocity, session 3	0.6	0.7	0.9	0.5	-0.8	-0.9	-0.9	-0.8	-1.0	0.8	0.6	0.9	0.9	0.9	-0.8
Locomotion distance, session 3	0.0	0.0	0.1	-0.3	0.1	-0.0	-0.3	-0.1	0.2	0.0	-0.3	0.1	0.1	0.2	-0.1
Stereotopy head waving bouts, day 3	0.7	0.9	1.3	-0.5	0.9	1.0	1.2	1.1	0.8	-1.0	-0.5	-1.0	-1.0	-1.1	1.0
Stereotopy head waving duration, day 3	0.1	0.1	0.4	-0.1	0.2	0.3	0.7	0.4	-0.1	-0.4	-0.0	-0.2	-0.3	-0.4	0.2
Locomotion velocity, session 7	1.7	1.9	3.0	1.6	-1.4	-1.3	-1.4	-1.5	-1.2	1.7	1.6	1.3	1.3	1.3	-0.6
Locomotion distance, session 7	1.1	1.4	2.0	0.9	-1.2	-1.2	-1.2	-1.4	-1.0	1.4	0.8	1.2	1.3	1.3	-1.0
Stereotopy head waving bouts, day 7	0.2	0.2	0.5	-0.7	0.5	0.5	0.7	0.6	0.2	-0.6	-0.6	-0.4	-0.3	-0.4	-0.0
Stereotopy head waving duration, day 7	0.4	0.5	0.8	-0.3	0.6	0.7	0.8	0.8	0.7	-0.6	-0.3	-0.7	-0.8	-0.8	0.9
Locomotion velocity, session 8	0.2	0.3	1.3	-0.2	-0.3	-0.3	-0.2	-0.1	-0.8	-0.1	0.1	0.5	0.4	0.5	-1.1
Locomotion distance, session 8	1.3	2.0	5.4	0.3	-1.2	-1.4	-1.1	-1.2	-1.7	0.9	0.3	1.5	1.7	1.7	-2.3
Degree of sensitization distance	1.1	1.1	1.6	0.9	-1.1	-1.1	-0.9	-1.2	-1.1	1.3	0.8	1.1	1.3	1.1	-0.9
Degree of sensitization stereotypy	0.0	0.0	0.2	-0.4	0.2	0.1	0.1	0.1	0.1	-0.2	-0.4	-0.0	0.1	0.1	-0.2
Condit. Reinf. active minus inactive responses	0.8	0.8	1.4	-0.6	1.0	1.0	0.7	1.0	1.2	-0.7	-0.7	-1.0	-1.0	-0.9	1.1
Condit. Reinf. active-inactive response ratio	2.8	3.0	3.5	-1.8	1.8	1.7	1.7	1.9	1.8	-1.8	-1.7	-1.7	-1.7	-1.7	1.3
Condit. Reinf. active responses	0.0	0.1	0.2	0.4	-0.1	-0.1	-0.3	-0.2	0.3	0.4	0.1	0.0	-0.0	0.1	0.4
Condit. Reinf. inactive responses	2.1	2.5	3.4	1.8	-1.6	-1.6	-1.8	-1.8	-1.3	1.8	1.2	1.6	1.6	1.6	-1.0
Incentive salience index mean	0.1	0.1	0.3	-0.1	0.3	0.3	0.1	0.3	0.4	-0.0	-0.1	-0.3	-0.4	-0.3	0.5
Condit. Reinf. lever presses	0.0	0.0	0.1	0.1	-0.1	-0.1	-0.2	-0.1	-0.0	0.2	-0.0	0.1	0.1	0.2	-0.1
Time in familiar zone, hab. session 1	0.5	0.4	1.0	0.3	-0.6	-0.7	-0.5	-0.7	-0.7	0.4	0.2	0.8	0.7	0.8	-1.0
Time in novel zone, hab. session 1	1.5	1.5	3.8	-0.6	1.1	1.3	0.9	1.2	1.5	-0.7	-0.4	-1.4	-1.3	-1.4	2.0
Total zone transitions, hab. session 1	0.2	0.3	0.6	0.6	-0.5	-0.5	-0.6	-0.6	-0.4	0.7	0.0	0.6	0.7	0.8	-0.5
Total locomotion distance, hab. session 1	2.3	3.3	4.4	1.4	-1.9	-2.0	-1.7	-1.8	-1.9	1.6	1.2	2.0	2.0	2.0	-2.1
Locomotion velocity, hab. session 1	2.1	3.0	4.8	1.2	-1.7	-1.9	-1.5	-1.7	-1.9	1.4	1.0	2.0	1.9	2.0	-2.2
Time in familiar zone, hab. session 2	0.0	0.0	0.1	-0.2	0.1	-0.0	-0.2	0.0	0.4	-0.2	-0.0	-0.0	-0.3	0.0	0.1
Time in novel zone, hab. session 2	0.3	0.3	1.2	0.2	0.4	0.6	0.7	0.5	0.4	-0.0	0.1	-0.7	-0.4	-0.8	1.1
Total zone transitions, hab. session 2	0.1	0.1	0.5	-0.2	-0.1	-0.2	-0.3	-0.3	-0.3	0.1	-0.5	0.3	0.4	0.5	-0.7
Total locomotion distance, hab. session 2	0.8	1.1	2.0	0.6	-1.0	-1.1	-1.0	-1.0	-1.2	0.8	0.7	1.2	1.2	1.2	-1.4
Locomotion velocity, hab. session 2	0.9	1.3	2.4	0.6	-1.1	-1.2	-1.1	-1.1	-1.3	0.8	0.7	1.3	1.2	1.3	-1.5
Novel to familiar place preference ratio	0.2	0.2	1.0	0.8	-0.2	0.0	0.0	0.0	0.2	0.3	0.7	-0.2	-0.3	-0.4	1.0
Novelty place preference	0.4	0.4	2.0	0.6	0.1	0.3	0.3	0.3	0.6	0.0	0.5	-0.6	-0.6	-0.7	1.4
Time in novel zone, NPP test	0.3	0.4	2.0	0.8	-0.1	0.2	0.1	0.1	0.5	0.3	0.8	-0.4	-0.5	-0.6	1.4
Total zone transitions, NPP test	0.0	0.0	0.1	0.2	-0.1	-0.1	-0.2	-0.2	-0.0	0.2	-0.1	0.2	0.1	0.2	-0.1
Total locomotion distance, NPP test	0.4	0.6	1.7	0.3	-0.6	-0.8	-0.7	-0.7	-0.8	0.5	0.1	0.9	0.9	1.0	-1.3
Locomotion velocity, NPP test	0.2	0.3	1.3	-0.1	-0.3	-0.5	-0.4	-0.4	-0.5	0.1	-0.3	0.6	0.6	0.7	-1.1
Pavlov. Cond. lever latency	0.5	0.7	1.4	-1.1	0.9	0.7	0.7	0.8	0.6	-1.2	-0.9	-0.7	-0.9	-0.7	0.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	0.1	-0.2	-0.3	-0.4	-0.4	-0.3	0.2	-0.1	0.3	0.4	0.4	-0.6
Pavlov. Cond. change in total contacts	0.1	0.1	0.4	0.6	-0.2	-0.1	-0.2	-0.2	-0.1	0.4	0.3	0.0	0.2	0.0	0.2
Pavlov. Cond. index score	0.1	0.2	0.5	0.7	-0.4	-0.3	-0.3	-0.4	-0.2	0.7	0.4	0.3	0.4	0.3	0.1
Pavlov. Cond. latency score	0.2	0.3	0.7	0.7	-0.5	-0.4	-0.5	-0.6	-0.3	0.8	0.4	0.4	0.5	0.5	-0.1
Pavlov. Cond. lever contacts	0.6	0.7	1.6	1.1	-0.9	-0.8	-0.8	-0.9	-0.6	1.3	0.9	0.7	0.9	0.8	-0.2
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	0.1	-0.4	-0.4	-0.2	-0.2	-0.5	0.1	0.3	0.4	0.3	0.3	-0.4
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.7	0.9	-0.5	-0.2	0.0	-0.3	-0.1	0.7	0.8	0.1	0.2	0.0	0.6
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.7	0.8	-0.5	-0.4	-0.5	-0.6	-0.4	0.7	0.7	0.5	0.5	0.4	-0.1
Pavlov. Cond. response bias	0.3	0.3	0.7	0.9	-0.6	-0.5	-0.6	-0.6	-0.4	0.8	0.6	0.5	0.5	0.5	-0.2
Bone: apparent density	0.2	0.3	0.5	-0.5	0.6	0.6	0.7	0.6	0.7	-0.7	-0.4	-0.6	-0.5	-0.5	0.4
Bone surface	0.1	0.1	0.5	-0.5	0.2	0.1	0.2	0.1	-0.2	-0.2	-0.5	0.1	0.3	0.2	-0.7
Bone volume	0.1	0.1	0.2	0.2	-0.2	-0.3	-0.2	-0.3	-0.3	0.3	0.2	0.3	0.5	0.4	-0.5
Bone: connectivity density	0.4	0.7	0.9	-0.5	0.8	0.8	0.8	0.9	0.9	-0.9	-0.6	-0.9	-0.9	-0.9	0.7
Bone: cortical apparent density	0.5	0.6	2.7	0.9	-0.1	0.2	0.1	0.2	0.6	-0.0	1.3	-0.5	-0.8	-0.8	1.6
Bone: cortical area	0.2	0.4	0.7	0.7	-0.6	-0.5	-0.5	-0.6	-0.6	0.8	0.8	0.4	0.7	0.4	-0.1
Bone: cortical porosity	1.6	1.7	3.6	-1.9	1.4	1.2	1.2	1.4	1.0	-1.6	-1.6	-1.1	-1.2	-1.1	0.4
Bone: cortical porosity	2.8	3.0	4.5	-2.1	1.8	1.7	1.7	1.9	1.6	-1.9	-1.8	-1.7	-1.7	-1.6	1.0
Bone: cortical thickness	0.3	0.6	0.7	-0.7	0.7	0.7	0.7	0.8	0.8	-0.6	-0.6	-0.9	-0.7	-0.8	0.8
Bone: cortical thickness	0.2	0.3	0.9	-0.2	-0.3	-0.5	-0.4	-0.4	-0.5	0.2	-0.3	0.5	0.7	0.6	-0.9
Bone: cortical tissue density	0.5	0.6	3.0	0.8	0.0	0.3	0.3	0.3	0.7	-0.1	1.2	-0.6	-1.0	-0.9	1.7
Bone: elastic displacement	0.4	0.5	1.7	-1.3	0.6	0.4	0.4	0.5	0.2	-0.9	-1.2	-0.2	-0.3	-0.1	-0.6
Bone: elastic work	0.2	0.3	0.9	-0.9	0.3	0.1	-0.1	0.2	0.0	-0.7	-1.0	0.1	-0.1	0.2	-0.8
Bone: endosteal estimation	2.0	4.2	5.9	1.7	-2.1	-2.1	-1.8	-2.1	-2.4	2.0	1.9	2.1	2.3	2.1	-2.1
Bone: endosteal perimeter	0.5	1.1	1.6	0.8	-1.0	-1.0	-1.0	-1.1	-1.3	1.0	0.9	1.1	1.2	1.1	-1.2
Bone: final force	0.1	0.1	0.3	0.3	-0.3	-0.2	-0.1	-0.2	-0.6	0.3	0.5	0.2	0.4	0.1	-0.2
Bone: final moment	0.1	0.1	0.2	0.3	-0.3	-0.2	-0.2	-0.2	-0.5	0.3	0.4	0.1	0.5	0.2	-0.1
Bone: marrow area	1.9	4.0	5.7	1.6	-2.0	-2.0	-1.8	-2.0	-2.4	1.9	1.8	2.1	2.2	2.1	-2.1
Bone: maximum diameter	0.1	0.1	0.4	0.4	0.0	0.2	0.2	0.1	0.1	0.2	0.5	-0.3	-0.1	-0.4	0.6
Bone: maximum force	0.4	0.6	1.2	0.7	-0.8	-0.8	-0.7	-0.7	-1.1	0.8	0.8	0.7	1.0	0.7	-0.8
Bone: maximum moment	0.4	0.7	1.1	0.7	-0.9	-0.8	-0.8	-0.8	-1.1	0.8	0.8	0.8	1.0	0.8	-0.8
Bone: minimum diameter	5.9	10.9	12.9	3.2	-3.5	-3.4	-3.2	-3.3	-3.5	3.6	3.4	3.3	3.5	3.2	-2.5
Bone: periosteal estimation	0.9	1.8	2.5	1.2	-1.4	-1.3	-1.2	-1.3	-1.6	1.4	1.4	1.3	1.6	1.3	-1.1
Bone: periosteal perimeter	0.4	0.7	1.1	0.7	-0.8	-0.8	-0.8	-0.9	-1.0	0.9	0.8	0.8	1.1	0.9	-0.9
Bone: post-yield work	0.2	0.3	0.9	0.9	-0.6	-0.5	-0.5	-0.4	-0.5	0.6	0.9	0.4	0.5	0.3	-0.1
Bone: stiffness	0.8	1.3	3.5	1.7	-1.2	-1.0	-0.9	-1.0	-1.0	1.5	1.9	0.8	1.0	0.7	0.0
Bone: tissue strength	0.8	0.8	1.1	1.0	-0.9	-0.9	-0.9	-0.9	-0.8	1.0	1.0	0.8	0.9	0.7	-0.4
Bone: trabecular number	0.2	0.3	0.6	0.0	0.4	0.5	0.6	0.6	0.6	-0.5	0.1	-0.6	-0.7	-0.6	0.8
Bone: trabecular spacing	0.3	0.3	1.7	0.2	0.3	0.5	0.3	0.3	0.8	0.1	-0.0	-0.7	-0.6	-0.7	1.3
Bone: trabecular thickness	0.1	0.2	0.5	0.0	-0.4	-0.5	-0.3	-0.4	-0.4	0.2	0.2	0.5	0.5	0.6	-0.7
Bone: trabecular tissue density	0.4	0.5	1.2	-0.2	0.6	0.7	0.6	0.8	0.6	-0.5	0.1	-0.8	-0.9	-0.9	1.1
Breakpoint value in progressive ratio session	0.2	0.2	0.7	0.9	-0.4	-0.3	-0.3	-0.4	-0.2	0.4	0.7	0.3	0.2	0.2	0.1
Distance traveled before self-admin	0.4	0.5	0.6	0.4	-0.7	-0.7	-0.7	-0.7	-0.7	0.7	0.5	0.7	0.8	0.8	-0.6
Distance traveled after self-admin	3.2	3.6	5.1	1.2	-1.8	-2.0	-1.7	-2.0	-2.1	1.7	1.1	2.1	2.1	2.2	-2.3
Delta time in closed arm before/after self-admin	1.5	1.5	2.4	-0.8	1.2	1.2	1.2	1.3	1.5	-1.2	-0.9	-1.3	-1.3	-1.3	1.4
Delta time in open arm before/after self-admin	1.3	1.3	1.7	1.3	-1.2	-1.1	-1.3	-1.3	-1.1	1.2	1.3	1.0	0.9	0.9	-0.6
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	-0.0	0.2	0.1	0.1	0.1	0.0	-0.2	-0.2	-0.1	-0.0	-0.0	-0.2
Extinction: sum of active levers before priming	0.7	0.7	1.1	0.6	-0.8	-0.9	-0.9	-0.8	-0.8	0.6	0.6	1.0	0.9	1.0	-1.0
Active lever presses in extinction session 6	0.7	0.6	1.1	1.1	-0.8	-0.8	-0.6	-0.8	-0.8	0.7	1.0	0.8	0.8	0.8	-0.5
Delta distance traveled before/after self-admin	0.4	0.5	1.0	0.4	-0.7	-0.7	-0.4	-0.7	-0.9	0.5	0.3	0.8	0.7	0.8	-1.0
Delta ambulatory time before/after self-admin	0.2	0.2	0.5	0.1	-0.4	-0.4	-0.2	-0.4	-0.5	0.2	0.1	0.5	0.4	0.5	-0.7
Time in closed arm before self-admin	0.9	1.0	2.1	0.6	-1.0	-1.0	-0.6	-0.9	-1.5	0.9	0.8	1.1	1.0	1.0	-1.1
Time in closed arm after self-admin	0.2	0.2	0.8	-0.9	0.3	0.2	0.5	0.5	-0.1	-0.5	-0.7	-0.1	0.0	-0.1	-0.4
Time in open arm before self-admin	0.8	0.9	2.0	-1.3	1.0	1.0	1.2	1.0	0.6	-1.1	-1.4	-0.7	-0.5	-0.6	-0.1
Time in open arm after self-admin	1.0	1.1	2.5	1.6	-1.1	-0.9	-1.2	-1.2	-0.8	1.2	1.5	0.9	0.7	0.7	-0.2
Sum of active levers in priming session hrs 5-6	1.2	1.2	2.2	1.3	-0.9	-1.0	-1.5	-1.1	-0.7	1.0	1.0	1.1	1.1	1.2	-0.9
Time to tail flick, vehicle, before self-admin	0.5	0.5	0.9	0.7	-0.7	-0.7	-0.6	-0.7	-0.9	0.9	0.8	0.7	0.7	0.7	-0.5
Time to tail flick, vehicle, after self-admin	1.1	1.2	3.3	-0.2	-0.9	-1.0	-0.6	-1.0	-1.4	0.8	-0.1	1.1	1.5	1.3	-1.8
Time to tail flick, test, before self-admin	0.1	0.1	0.2	0.0	-0.2	-0.2	0.0	-0.1	-0.5	0.2	0.1	0.3	0.4	0.2	-0.5
Time to tail flick, test, after self-admin	2.2	2.2	3.9	1.2	-1.7	-1.4	-1.0	-1.4	-2.0	1.7	1.5	1.5	1.6	1.4	-1.3
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.4	-0.0	-0.3	-0.2	-0.1	-0.3	-0.3	0.3	-0.1	0.3	0.6	0.4	-0.5
Delta time to tail flick, test, before/after SA	0.9	0.8	1.5	1.0	-1.0	-0.8	-0.8	-0.9	-0.9	1.2	1.2	0.7	0.7	0.6	-0.2
Ambulatory time before self-admin	0.6	0.6	1.2	0.7	-0.8	-0.7	-0.6	-0.8	-1.1	0.7	0.7	0.8	0.8	0.7	-0.8
Ambulatory time after self-admin	3.2	3.5	4.4	1.4	-1.8	-2.0	-1.8	-2.0	-2.0	1.7	1.3	2.0	2.0	2.1	-2.1
Total heroin consumption	1.7	2.0	2.6	1.1	-1.5	-1.5	-1.1	-1.4	-1.6	1.3	1.2	1.6	1.5	1.6	-1.4
Area under the delay curve	0.1	0.1	0.3	0.0	0.3	0.4	0.2	0.2	0.3	-0.0	0.4	-0.4	-0.3	-0.4	0.5
Delay disc. indifference point, 0s delay	0.2	0.2	0.4	-0.1	0.4	0.5	0.3	0.4	0.4	-0.2	-0.0	-0.5	-0.5	-0.6	0.6
Delay disc. indifference point, 16s delay	1.2	1.2	2.7	-0.4	1.1	1.2	0.8	0.9	1.4	-0.6	-0.0	-1.3	-1.2	-1.3	1.6
Delay disc. indifference point, 2s delay	2.4	2.7	4.1	1.7	-1.7	-1.5	-1.3	-1.7	-1.9	1.8	2.0	1.6	1.6	1.5	-1.2
Delay disc. indifference point, 24s delay	0.1	0.1	0.4	-0.6	0.5	0.5	0.5	0.4	0.1	-0.4	-0.2	-0.4	-0.3	-0.4	0.1
Delay disc. indifference point, 4s delay	0.3	0.3	1.5	0.9	-0.4	-0.2	-0.5	-0.5	-0.1	0.5	1.2	0.2	0.0	0.1	0.5
Delay disc. indifference point, 8s delay	1.7	1.8	2.4	-0.9	1.4	1.5	1.3	1.3	1.5	-1.1	-0.6	-1.5	-1.4	-1.5	1.5
Delay discount exponential model param	0.1	0.1	0.4	-0.2	-0.1	-0.2	-0.0	0.0	-0.1	-0.1	-0.6	0.2	0.1	0.2	-0.3
Delay discount hyperbolic model param	0.1	0.1	0.8	-0.5	0.2	0.1	0.3	0.3	0.2	-0.4	-0.9	-0.1	-0.2	-0.1	-0.1
Fecal boli incidents, locomotor time 1	1.1	1.2	2.7	-1.6	1.2	1.0	1.0	1.1	1.1	-1.2	-1.3	-1.0	-0.8	-0.9	0.3
Change in fecal boli incidents, locomotor task	0.1	0.1	0.3	-0.2	0.2	0.2	0.4	0.3	-0.1	-0.5	-0.2	-0.1	-0.4	-0.2	-0.1
Time >=10cm from walls, locomotor time 1	1.8	1.8	3.4	-1.2	1.5	1.3	1.1	1.2	1.8	-1.3	-1.5	-1.3	-1.3	-1.2	1.1
Bouts of movement, locomotor time 1	0.9	1.0	1.3	-0.9	1.0	1.0	0.8	1.0	1.0	-0.9	-0.9	-1.1	-1.0	-1.1	1.0
Total resting periods, locomotor time 1	0.7	0.7	1.0	-0.8	0.9	0.9	0.6	0.9	1.0	-0.8	-0.7	-0.9	-0.9	-1.0	1.0
Rest time, locomotor task time 1	0.9	0.9	2.1	0.2	-0.8	-1.1	-1.0	-0.9	-0.9	0.6	0.3	1.1	1.0	1.2	-1.5
Distance moved, locomotor task time 1	0.1	0.1	0.3	-0.2	0.4	0.6	0.4	0.3	0.2	-0.2	-0.3	-0.5	-0.4	-0.5	0.4
Vertical activity count, locomotor time 1	0.4	0.4	1.7	1.1	-0.1	0.2	0.1	-0.1	0.3	0.7	0.9	-0.4	-0.2	-0.4	1.3
Time >=10cm from walls, locomotor time 2	0.2	0.3	1.0	-0.7	0.5	0.3	0.3	0.3	0.7	-0.6	-1.0	-0.2	-0.3	-0.0	-0.2
Bouts of movement, locomotor time 2	0.1	0.2	0.4	0.4	-0.4	-0.4	-0.4	-0.3	-0.4	0.3	0.7	0.4	0.2	0.3	-0.3
Total resting periods, locomotor time 2	0.1	0.1	0.3	0.3	-0.3	-0.3	-0.2	-0.2	-0.3	0.1	0.6	0.2	-0.0	0.1	-0.1
Rest time, locomotor task time 2	0.9	1.0	2.8	-0.0	-0.8	-1.1	-0.9	-0.9	-1.2	0.6	0.2	1.2	0.9	1.2	-1.7
Distance moved, locomotor task time 2	1.3	1.5	2.1	-0.7	1.3	1.5	1.2	1.3	1.1	-1.1	-0.9	-1.4	-1.2	-1.3	1.2
Vertical activity count, locomotor time 2	0.3	0.3	1.5	0.8	0.3	0.5	0.3	0.3	0.6	0.1	0.5	-0.6	-0.4	-0.6	1.2
Weight adjusted by age	1.1	1.2	1.9	-1.4	1.3	1.1	1.3	1.2	0.8	-1.3	-1.3	-1.0	-0.8	-0.9	0.3
Seeking ratio, delayed vs. immediate footshock	1.2	1.4	1.8	1.0	-1.2	-1.3	-1.3	-1.2	-1.0	1.1	0.9	1.3	1.2	1.3	-1.1
Locomotion in novel chamber	0.0	0.0	0.1	0.0	-0.0	0.0	0.0	-0.1	-0.0	0.2	-0.1	-0.0	-0.1	-0.0	0.2
Locomotion in novel chamber post-restriction	0.7	0.8	2.6	1.2	-0.9	-0.8	-0.8	-0.8	-0.5	1.0	1.6	0.6	0.7	0.5	0.2
Progressive ratio	0.5	0.6	1.5	-0.9	0.7	0.7	1.0	0.7	0.3	-1.0	-1.2	-0.6	-0.5	-0.7	-0.1
Food seeking constrained by brief footshock	0.1	0.1	0.2	-0.1	0.2	0.2	0.0	0.3	0.4	-0.3	-0.2	-0.3	-0.3	-0.3	0.3
Seeking ratio, punishment vs. effort	0.5	0.6	1.6	1.1	-0.8	-0.7	-1.0	-0.7	-0.3	1.0	1.3	0.6	0.4	0.6	0.2
Run reversals in cocaine runway, females	3.1	3.1	4.3	1.4	-1.9	-1.8	-1.5	-1.8	-2.1	1.9	1.3	1.9	1.9	1.8	-1.7
Run reversals in cocaine runway, males	0.3	0.3	0.9	-0.7	0.6	0.6	0.7	0.4	0.2	-0.5	-0.9	-0.4	-0.4	-0.4	0.1
Latency to leave start box in cocaine runway	2.5	2.7	3.9	1.8	-1.7	-1.8	-2.0	-1.8	-1.4	1.9	1.6	1.7	1.6	1.6	-0.9
Latency to leave start box in cocaine runway, F	4.1	4.5	5.8	2.3	-2.3	-2.2	-2.3	-2.2	-1.9	2.4	2.1	2.1	2.0	2.0	-1.2
Latency to leave start box in cocaine runway, M	0.1	0.1	0.4	-0.6	0.4	0.3	0.2	0.3	0.4	-0.4	-0.4	-0.3	-0.2	-0.3	0.0
Cd content in liver	1.6	1.7	2.4	-1.0	1.3	1.3	1.1	1.4	1.3	-1.4	-1.0	-1.4	-1.6	-1.4	1.3
Co content in liver	0.1	0.2	0.3	0.4	-0.5	-0.5	-0.4	-0.3	-0.5	0.3	0.4	0.5	0.2	0.3	-0.2
Cu content in liver	0.7	0.8	1.4	1.1	-1.0	-0.9	-0.9	-0.8	-0.9	1.0	1.2	0.8	0.8	0.7	-0.4
Fe content in liver	0.6	0.8	2.1	0.1	0.6	0.8	0.8	0.9	0.9	-0.6	-0.0	-0.9	-1.2	-1.1	1.4
K content in liver	1.2	1.2	3.1	1.8	-1.2	-1.0	-1.1	-1.0	-0.7	1.4	1.7	0.8	0.5	0.6	0.4
Mg content in liver	0.9	1.0	2.8	1.7	-1.0	-0.7	-0.9	-0.8	-0.5	1.3	1.7	0.6	0.4	0.4	0.6
Mn content in liver	0.1	0.1	0.2	-0.3	0.3	0.3	0.4	0.3	0.1	-0.2	-0.2	-0.3	-0.1	-0.3	0.2
Na content in liver	0.7	0.7	2.2	1.5	-0.9	-0.7	-0.7	-0.8	-0.3	1.1	1.4	0.5	0.3	0.4	0.5
Rb content in liver	1.1	1.3	1.8	-0.8	1.1	1.2	1.3	1.2	1.1	-1.1	-0.6	-1.3	-1.2	-1.3	1.3
Se content in liver	0.1	0.1	0.3	0.5	-0.2	-0.1	-0.1	-0.1	-0.2	0.2	0.6	0.1	0.1	-0.0	0.2
Sr content in liver	0.4	0.4	1.6	-1.1	0.6	0.4	0.6	0.4	0.2	-0.5	-1.3	-0.3	0.1	-0.1	-0.5
Zn content in liver	0.9	1.0	1.2	1.0	-1.1	-1.1	-1.0	-1.1	-1.1	1.0	1.1	1.1	0.8	1.0	-0.8