Hub : Genes

ENSRNOG00000063658

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000063658	0.07	0.05	9.8e-07	0.06	0.05	0.04	0.04	9.0e-07	2.7e-06	9.4e-06	1.0e-05
2	Adipose	intron excision ratio	chr3:116406947:116408408	0.05	0.04	5.5e-05	0.03	0.03	0.04	0.04	1.7e-04	1.6e-04	4.5e-05	4.8e-05
3	Brain	intron excision ratio	chr3:116408104:116408408	0.04	0.03	1.6e-03	0.03	0.02	0.01	0.02	6.7e-04	4.4e-03	2.0e-02	2.3e-03
4	PL	gene expression	ENSRNOG00000063658	0.07	0.05	5.1e-04	0.01	0.03	0.03	0.02	3.4e-02	3.0e-03	1.9e-03	1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	0.6	1.9	5.0	1.6	-0.3	2.2	-0.2
BMI without tail	1.9	4.0	11.6	2.0	-0.1	3.4	-0.6
Body weight	2.4	10.0	26.9	1.7	1.3	5.2	-2.9
Epididymis fat weight	0.3	0.7	1.8	0.6	0.1	1.4	-0.8
Glucose	0.2	0.2	0.4	-0.2	0.6	0.6	-0.4
Heart weight	4.5	6.4	10.9	-1.0	2.7	2.6	-3.3
Left kidney weight	1.3	3.8	6.3	-1.5	2.3	1.3	-2.5
Right kidney weight	1.2	3.4	6.2	-1.4	2.0	1.2	-2.5
Tail length	2.0	6.2	17.7	1.9	0.4	4.2	-1.8
Length with tail	2.1	7.7	13.1	-0.0	2.1	3.6	-3.6
Length without tail	0.8	1.8	3.8	-0.8	1.4	1.0	-2.0
Liver weight, left	1.3	2.2	3.9	-1.9	2.0	0.1	-1.1
Liver weight, right	0.0	0.0	0.1	-0.2	0.1	-0.3	-0.0
Parametrial fat weight	0.2	0.3	0.6	0.3	-0.5	-0.6	0.8
Retroperitoneal fat weight	0.0	0.2	0.3	-0.5	0.6	0.1	-0.1
Intraocular pressure	0.5	0.7	0.9	1.0	-0.7	0.6	1.0
Extensor digitorum longus weight	0.1	0.5	0.9	0.8	-0.4	1.0	0.5
Soleus weight	0.2	0.6	0.9	-0.5	1.0	0.9	-0.7
Tibialis anterior weight	0.5	1.8	5.3	0.7	0.6	2.3	-0.9
Tibia length	2.3	6.4	13.4	3.1	-1.5	3.7	-0.5
Number of licking bursts	0.6	0.7	1.6	0.7	-0.3	0.7	1.3
Food consumed during 24 hour testing period	0.3	0.4	0.7	-0.9	0.4	-0.8	0.2
Times rat made contact with spout	0.0	0.0	0.0	-0.2	0.1	-0.2	-0.0
Mean time between licks in bursts	0.4	0.5	1.0	0.7	-1.0	-0.3	0.8
Mean num. licks in bursts	1.0	1.2	2.1	-1.1	0.6	-0.9	-1.4
Std. dev. time between licks in bursts	0.4	0.4	1.2	0.2	0.4	1.1	-0.6
Water consumed over 24 hours	0.1	0.1	0.2	0.4	-0.4	0.1	0.5
Indifference point 0 sec	1.2	1.9	2.9	-1.7	1.6	-0.3	-1.4
Indifference point AUC	0.2	0.2	0.4	0.0	0.4	0.6	-0.6
Indifference point function ln k	0.4	0.5	1.0	-0.7	1.0	0.4	-0.6
Indifference point function log k	0.4	0.5	1.0	-0.7	1.0	0.4	-0.6
Delay discounting total patch changes 0 sec	1.3	2.1	3.2	-1.8	1.7	-0.2	-1.5
Delay discounting total patch changes 12 sec	0.1	0.1	0.2	-0.0	-0.1	-0.2	-0.5
Delay discounting total patch changes 18 sec	1.1	1.4	2.9	-1.7	1.2	-1.1	-0.2
Delay discounting total patch changes 24 sec	2.3	2.9	6.0	-2.5	2.0	-1.3	-0.3
Delay discounting total patch changes 6 sec	1.4	2.1	3.2	-1.4	1.7	0.4	-1.8
Delay discounting time to switch 0 sec	3.2	4.8	7.7	1.3	-2.6	-1.8	2.8
Delay discounting water rate 0 sec	4.1	6.5	10.4	-1.3	2.9	2.4	-3.2
Delay discounting water rate 12 sec	1.0	1.5	3.0	-1.1	1.7	1.0	-0.8
Delay discounting water rate 18 sec	0.3	0.4	0.9	0.2	0.2	1.0	-0.8
Delay discounting water rate 24 sec	0.4	0.6	1.1	0.4	0.2	1.1	-0.9
Delay discounting water rate 6 sec	0.9	1.3	3.0	-0.0	1.0	1.7	-1.0
Locomotor activity	0.2	0.3	0.7	0.4	0.1	0.9	-0.6
Locomotor testing distance	0.2	0.3	0.4	-0.6	0.6	-0.2	-0.6
Locomotor testing rearing	1.6	2.5	5.3	-1.3	1.7	0.6	-2.3
Light reinforcement 1	0.4	0.7	1.9	0.3	0.5	1.4	-0.8
Light reinforcement 2	0.2	0.3	0.6	0.2	0.4	0.8	-0.6
Reaction time number correct	0.4	0.5	0.8	-0.9	0.9	-0.0	-0.7
Reaction time mean minus median	0.4	0.5	1.6	-0.6	-0.1	-1.3	0.3
Reaction time mean minus median AUC	0.3	0.3	0.9	-0.6	0.2	-0.9	-0.2
Reaction time num false alarms	2.4	3.4	6.7	-0.9	1.9	1.6	-2.6
Reaction time num false alarms AUC	1.6	2.3	4.9	-0.3	1.3	1.6	-2.2
Reaction time trials correct on left	0.4	0.5	0.8	-0.9	0.9	-0.0	-0.7
Reaction time trials on left	0.4	0.6	0.9	-0.9	0.9	0.1	-0.8
Reaction time mean	0.0	0.0	0.1	0.3	-0.0	0.2	-0.0
Reaction time mean AUC	0.0	0.0	0.1	0.2	-0.1	0.2	-0.0
Median of all reaction times	0.1	0.1	0.4	0.3	0.2	0.6	-0.2
Reaction time omissions	0.9	1.2	3.8	-0.4	0.8	0.5	-1.9
Reaction time false alarm rate	1.0	1.4	3.3	-0.1	0.9	1.3	-1.8
Reaction time premature initiation rate	0.4	0.6	0.9	0.7	-0.3	0.9	0.9
Reaction time premature initiations	0.1	0.2	0.3	0.0	0.2	0.6	0.5
Std. dev. reaction times	0.1	0.1	0.2	0.3	-0.0	0.4	-0.4
Reaction time trials completed	0.4	0.6	0.9	-0.9	0.9	0.1	-0.8
Reaction time trials AUC	0.4	0.5	0.8	-0.8	0.9	0.0	-0.8
Social response proportion	1.1	1.1	2.9	-0.8	1.0	0.4	-1.7
Social responses	1.8	2.3	6.2	0.3	0.5	1.7	-2.5
Social time	0.2	0.2	0.6	0.4	-0.3	0.3	-0.8
Conditioned locomotion	2.4	2.8	5.4	-1.1	1.9	1.1	-2.3
Cocaine response after cond. corrected	0.2	0.2	0.3	-0.6	0.4	-0.5	-0.4
Cocaine response after cond. not corrected	0.2	0.2	0.5	-0.5	0.1	-0.7	-0.3
Cocaine response before conditioning	0.2	0.2	0.3	0.3	-0.5	-0.6	0.3
Saline control response	2.0	2.7	6.0	0.3	1.0	2.4	-1.9
Condit. Reinf. active minus inactive responses	2.2	2.8	4.8	-0.5	1.6	1.8	-2.2
Condit. Reinf. active-inactive response ratio	2.0	2.1	3.9	-0.2	1.4	2.0	-1.6
Condit. Reinf. active responses	2.5	3.4	6.4	-0.2	1.5	2.2	-2.5
Condit. Reinf. inactive responses	0.5	0.6	1.4	-0.3	0.7	0.6	-1.2
Condit. Reinf. lever presses	0.5	0.7	2.2	0.5	0.3	1.5	-0.7
Condit. Reinf. lever reinforcers received	2.1	3.0	5.2	-0.4	1.6	2.0	-2.3
Pavlov. Cond. lever latency	1.3	1.8	5.1	-0.4	-0.8	-2.3	1.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	-0.4	0.5	0.3	-0.3
Pavlov. Cond. change in total contacts	0.8	1.1	3.2	0.7	0.2	1.8	-0.9
Pavlov. Cond. index score	0.9	1.2	3.7	0.5	0.4	1.9	-0.8
Pavlov. Cond. latency score	0.7	0.9	2.5	0.2	0.6	1.6	-0.8
Pavlov. Cond. lever contacts	1.3	1.8	4.9	0.3	0.8	2.2	-1.2
Pavlov. Cond. magazine entry number	0.3	0.3	1.2	-0.3	-0.1	-1.1	0.2
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.4	-0.6	0.5	-0.4	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.8	0.5	0.3	1.7	-0.7
Pavlov. Cond. response bias	1.4	2.0	5.5	0.4	0.9	2.3	-1.2
Conditioned reinforcement - actives	0.3	0.3	1.0	0.3	0.3	1.0	0.0
Conditioned reinforcement - inactives	4.6	5.2	8.3	-2.0	2.9	1.2	-2.6
Conditioned locomotion	0.2	0.2	0.7	0.1	0.3	0.9	0.4
Intermittent access intake day 1-15 change	1.0	0.9	2.4	0.1	1.0	1.6	-0.6
Intermittent access intake escalation	0.7	0.7	1.8	0.2	0.9	1.3	-0.3
Intermittent access intake escalation 2	0.1	0.1	0.3	0.1	0.5	0.6	-0.0
Intermitt. access day 1 inactive lever presses	1.4	1.5	2.4	-0.9	1.5	1.1	-1.3
Intermitt. access day 15 inactive lever presses	3.0	3.4	6.4	-2.3	2.5	0.4	-1.3
Intermitt. access escalation Index	1.1	1.0	1.8	1.0	-1.3	-0.7	0.9
Intermittent access day 1 total infusions	0.1	0.1	0.2	0.0	-0.3	-0.4	0.4
Intermittent access day 15 total infusions	0.3	0.4	0.9	-0.1	0.8	0.9	-0.1
Intermittent access terminal intake (last 3 days)	0.6	0.6	1.5	-0.7	1.2	0.5	-0.5
Intermittent access total infusions	0.4	0.4	0.9	-0.8	1.0	0.1	-0.2
Intermittent access day 1 locomotion	0.2	0.2	0.4	-0.3	0.6	0.6	0.2
Intermittent access day 15 total locomotion	1.8	2.0	3.8	-1.4	2.0	0.7	-1.3
Intermittent access total locomotion	0.8	0.9	1.8	-0.7	1.4	0.9	-0.4
Intermittent access standard deviation	0.1	0.1	0.3	0.1	0.3	0.5	-0.3
Cocaine induced anxiety	3.7	4.3	9.2	-2.6	0.9	-3.0	0.3
Post-drug Anxiety	1.3	1.5	3.8	-1.4	0.3	-1.9	-0.1
Baseline Anxiety	0.7	0.7	1.5	1.1	-0.4	1.2	0.0
Lifetime Intake	0.2	0.3	0.5	-0.4	0.7	0.4	-0.4
Incentive Sensitization - Responses	0.0	0.0	0.2	0.1	-0.0	0.1	-0.4
Incentive Sensitization - Breakpoint	0.1	0.1	0.2	-0.2	0.1	-0.1	-0.5
Progressive ratio test 1 active lever presses	1.1	1.1	2.6	0.4	0.6	1.6	-1.1
Progressive ratio test 1 breakpoint	1.2	1.3	3.2	0.5	0.6	1.8	-1.2
Progressive ratio test 1 inactive lever presses	1.9	2.1	3.7	-1.0	1.6	0.9	-1.9
Progressive ratio test 2 active lever presses	0.6	0.7	1.3	-0.8	1.1	0.4	-0.9
Progressive ratio test 2 breakpoint	0.4	0.4	0.7	-0.5	0.8	0.3	-0.8
Progressive ratio test 2 inactive lever presses	2.3	2.6	4.9	-1.5	2.2	1.1	-1.5
Total sessions with >9 infusions	0.2	0.2	0.4	0.6	-0.4	0.2	0.3
Short access day 1 total inactive lever presses	0.1	0.1	0.2	-0.2	0.5	0.5	-0.0
Short access day 10 total inactive lever presses	2.8	3.1	6.5	-2.6	2.0	-1.1	-0.9
Short access day 1 total infusions	0.0	0.0	0.0	0.0	-0.0	-0.0	0.0
Short access day 10 total infusions	0.1	0.1	0.3	0.1	-0.1	-0.1	0.6
Short access total infusions	0.0	0.0	0.0	0.2	-0.1	0.1	-0.1
Short access day 1 locomotion	0.2	0.3	0.4	-0.6	0.4	-0.5	0.5
Short access day 10 total locomotion	0.4	0.4	1.6	0.4	0.3	1.2	0.1
Short access total locomotion	0.3	0.3	0.5	-0.3	0.7	0.7	-0.2
Compulsive drug intake	1.4	1.4	3.3	0.5	-1.1	-0.9	1.8
One hour access (0.3 mA shock)	0.4	0.5	1.1	-0.4	1.1	0.8	-0.2
One hour access (shock baseline)	0.3	0.4	0.6	-0.4	0.8	0.4	-0.8
Number of responses in last shaping day	0.0	0.0	0.0	0.0	-0.1	-0.2	-0.2
Context. condit. distance diff. score	1.8	2.2	4.5	-1.3	2.1	1.0	-1.2
Locomotion velocity, session 1	0.2	0.2	0.5	-0.3	0.0	-0.6	-0.7
Locomotion distance, session 1	1.5	1.9	3.0	-1.2	1.6	0.7	-1.7
Locomotion velocity, session 2	0.1	0.1	0.2	0.1	-0.4	-0.3	0.1
Locomotion distance, session 2	2.4	3.5	6.7	-1.1	2.0	1.4	-2.6
Locomotion velocity, session 3	1.0	1.1	2.0	1.4	-1.0	1.2	0.3
Locomotion distance, session 3	3.4	3.7	10.1	1.9	-0.3	3.2	-0.9
Stereotopy head waving bouts, day 3	2.1	2.6	5.1	-2.3	1.3	-1.7	-0.6
Stereotopy head waving duration, day 3	0.9	1.1	2.7	-1.2	0.3	-1.6	0.2
Locomotion velocity, session 7	0.9	1.0	3.0	-0.0	0.8	1.7	-0.7
Locomotion distance, session 7	3.0	3.9	6.0	-1.1	2.4	2.1	-2.0
Stereotopy head waving bouts, day 7	0.3	0.4	0.6	0.7	-0.8	0.2	0.4
Stereotopy head waving duration, day 7	0.8	1.0	1.9	1.0	-1.4	-0.4	1.0
Locomotion velocity, session 8	0.7	0.8	1.5	-0.6	1.0	0.7	-1.2
Locomotion distance, session 8	5.2	7.8	11.4	-1.7	3.4	2.5	-3.3
Degree of sensitization distance	2.8	2.8	5.7	-2.4	2.1	-1.0	-0.7
Degree of sensitization stereotypy	1.5	1.6	3.2	1.8	-1.3	1.1	0.5
Condit. Reinf. active minus inactive responses	0.2	0.2	0.3	0.5	-0.1	0.6	-0.5
Condit. Reinf. active-inactive response ratio	0.5	0.6	1.2	-0.2	0.7	0.7	-1.1
Condit. Reinf. active responses	0.1	0.1	0.1	0.3	-0.1	0.3	-0.3
Condit. Reinf. inactive responses	0.1	0.1	0.2	-0.5	0.3	-0.3	-0.2
Incentive salience index mean	0.2	0.2	0.5	-0.2	0.5	0.4	-0.7
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.2	0.4	0.3	-0.1
Time in familiar zone, hab. session 1	0.6	0.5	1.2	0.2	-0.8	-0.6	1.1
Time in novel zone, hab. session 1	1.3	1.3	2.1	-1.0	1.5	0.3	-1.4
Total zone transitions, hab. session 1	0.9	1.3	2.2	-0.9	1.3	0.8	-1.5
Total locomotion distance, hab. session 1	2.3	3.2	5.1	-1.8	2.3	0.5	-2.1
Locomotion velocity, hab. session 1	2.2	3.2	4.9	-1.8	2.2	0.6	-2.1
Time in familiar zone, hab. session 2	0.4	0.4	1.2	-0.5	-0.2	-1.1	0.4
Time in novel zone, hab. session 2	0.4	0.4	1.2	0.5	0.2	1.1	-0.4
Total zone transitions, hab. session 2	1.2	1.6	3.9	0.4	0.7	2.0	-1.4
Total locomotion distance, hab. session 2	3.6	4.8	7.4	-2.0	2.7	0.8	-2.7
Locomotion velocity, hab. session 2	3.6	4.9	7.6	-2.3	2.7	0.4	-2.6
Novel to familiar place preference ratio	0.4	0.5	0.9	-1.0	0.9	-0.4	-0.2
Novelty place preference	0.3	0.3	0.7	-0.8	0.6	-0.6	0.1
Time in novel zone, NPP test	0.3	0.3	0.6	-0.8	0.7	-0.4	-0.0
Total zone transitions, NPP test	0.3	0.4	0.9	0.1	0.5	0.9	-0.6
Total locomotion distance, NPP test	3.6	5.0	8.3	-2.1	2.9	0.9	-2.5
Locomotion velocity, NPP test	2.8	4.1	6.9	-2.1	2.6	0.6	-2.2
Pavlov. Cond. lever latency	0.7	0.9	1.6	1.3	-1.1	0.7	0.5
Pavlov. Cond. magazine entry latency	0.6	0.8	1.5	-0.8	1.2	0.4	-1.0
Pavlov. Cond. change in total contacts	0.5	0.5	1.0	-0.8	1.0	0.1	-0.5
Pavlov. Cond. index score	0.4	0.5	0.9	-0.9	0.9	-0.2	-0.6
Pavlov. Cond. latency score	0.8	1.1	1.8	-1.3	1.3	-0.5	-0.8
Pavlov. Cond. lever contacts	0.6	0.7	1.1	-1.0	1.1	-0.2	-0.8
Pavlov. Cond. magazine entry number	0.2	0.2	0.6	-0.5	-0.0	-0.8	0.1
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.4	0.3	-0.0	0.7	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.3	0.5	-0.7	0.7	-0.2	-0.5
Pavlov. Cond. response bias	0.2	0.2	0.4	-0.1	0.6	0.6	-0.5
Bone: apparent density	1.3	2.2	2.8	-0.6	1.6	1.7	-1.7
Bone surface	1.0	1.8	3.0	-0.7	1.5	1.2	-1.7
Bone volume	1.2	2.0	2.9	-0.8	1.7	1.3	-1.7
Bone: connectivity density	0.7	1.1	1.5	-0.5	1.2	1.2	-1.2
Bone: cortical apparent density	0.3	0.4	1.0	1.0	-0.8	0.1	0.1
Bone: cortical area	1.3	2.0	3.9	0.2	0.9	2.0	-1.8
Bone: cortical porosity	3.1	3.3	6.1	2.0	-2.5	-0.3	1.7
Bone: cortical porosity	2.9	3.1	5.5	2.2	-2.3	0.3	1.5
Bone: cortical thickness	0.3	0.5	1.3	0.5	0.1	0.8	-1.1
Bone: cortical thickness	0.1	0.2	0.3	0.6	-0.4	0.4	0.1
Bone: cortical tissue density	0.3	0.4	0.9	1.0	-0.8	0.0	0.1
Bone: elastic displacement	1.5	1.7	2.9	1.7	-1.7	0.3	1.0
Bone: elastic work	0.5	0.7	1.3	1.2	-1.0	0.2	0.5
Bone: endosteal estimation	0.5	1.0	2.3	-0.4	1.1	1.5	-0.8
Bone: endosteal perimeter	1.3	2.7	4.7	-0.4	1.5	2.2	-1.9
Bone: final force	1.6	2.7	5.2	0.1	1.3	2.3	-2.0
Bone: final moment	1.3	2.1	4.2	0.1	1.1	2.1	-1.7
Bone: marrow area	0.5	1.1	2.1	-0.5	1.2	1.4	-0.8
Bone: maximum diameter	2.2	4.1	6.9	-0.2	1.7	2.6	-2.6
Bone: maximum force	0.4	0.8	1.4	-0.4	1.0	0.8	-1.2
Bone: maximum moment	0.2	0.4	0.7	-0.4	0.8	0.5	-0.9
Bone: minimum diameter	0.5	0.9	2.0	0.2	0.6	1.4	-1.1
Bone: periosteal estimation	1.1	2.2	5.0	0.0	1.2	2.2	-1.6
Bone: periosteal perimeter	1.5	2.6	4.3	-0.3	1.4	2.0	-2.1
Bone: post-yield work	0.4	0.6	1.3	-0.7	-0.1	-1.1	0.7
Bone: stiffness	1.1	1.7	3.4	-0.7	1.3	1.0	-1.8
Bone: tissue strength	0.6	0.5	0.9	-0.7	0.9	0.2	-0.9
Bone: trabecular number	1.5	2.3	4.5	-0.3	1.5	2.1	-1.5
Bone: trabecular spacing	0.2	0.3	0.8	-0.1	-0.3	-0.9	0.4
Bone: trabecular thickness	0.5	0.6	1.1	-0.2	0.7	0.8	-1.0
Bone: trabecular tissue density	1.2	1.6	3.0	-0.7	1.4	1.0	-1.7
Breakpoint value in progressive ratio session	0.7	0.7	1.5	0.9	-0.0	1.2	-0.8
Distance traveled before self-admin	3.6	3.8	5.7	-0.7	2.0	2.2	-2.4
Distance traveled after self-admin	1.5	1.6	4.0	0.1	0.9	2.0	-1.3
Delta time in closed arm before/after self-admin	0.1	0.1	0.4	-0.0	-0.4	-0.6	0.0
Delta time in open arm before/after self-admin	0.9	0.8	1.4	-0.4	1.2	1.1	-0.6
Diff in mean of infusions in LGA sessions	0.4	0.4	0.6	0.2	-0.6	-0.8	0.8
Extinction: sum of active levers before priming	0.1	0.1	0.3	0.5	-0.3	0.1	0.3
Active lever presses in extinction session 6	0.3	0.3	0.5	-0.7	0.7	-0.5	0.3
Delta distance traveled before/after self-admin	0.4	0.5	0.7	0.9	-0.9	-0.0	0.7
Delta ambulatory time before/after self-admin	1.8	2.0	2.9	0.7	-1.6	-1.4	1.7
Time in closed arm before self-admin	0.5	0.6	1.7	-0.1	-0.2	-0.7	1.3
Time in closed arm after self-admin	1.6	1.7	2.7	0.9	-1.6	-1.0	1.4
Time in open arm before self-admin	0.2	0.2	0.3	0.5	-0.6	-0.2	0.3
Time in open arm after self-admin	1.3	1.4	2.7	-1.3	1.6	0.7	-0.9
Sum of active levers in priming session hrs 5-6	0.8	0.8	1.5	-0.8	1.0	0.5	-1.2
Time to tail flick, vehicle, before self-admin	1.3	1.3	2.4	-1.5	1.4	-0.8	0.6
Time to tail flick, vehicle, after self-admin	0.3	0.3	1.1	0.3	-0.3	0.3	1.0
Time to tail flick, test, before self-admin	0.5	0.5	0.6	0.8	-0.7	0.8	-0.4
Time to tail flick, test, after self-admin	1.3	1.4	2.5	-1.6	0.9	-1.4	0.5
Delta time to tail flick, vehicle, before/after SA	1.0	0.9	2.2	1.0	-0.4	1.5	-0.6
Delta time to tail flick, test, before/after SA	1.8	1.6	3.1	-1.8	1.4	-1.1	0.3
Ambulatory time before self-admin	2.0	2.1	4.6	0.0	1.3	2.1	-1.4
Ambulatory time after self-admin	0.7	0.8	2.2	0.8	0.1	1.5	-0.6
Total heroin consumption	1.3	1.5	3.9	-0.1	0.8	1.2	-2.0
Area under the delay curve	0.1	0.1	0.2	0.1	-0.4	-0.5	0.4
Delay disc. indifference point, 0s delay	2.5	2.7	5.5	-0.0	-1.5	-2.3	1.8
Delay disc. indifference point, 16s delay	0.2	0.2	0.4	-0.1	-0.2	-0.6	0.6
Delay disc. indifference point, 2s delay	0.0	0.0	0.1	-0.2	-0.1	-0.3	-0.1
Delay disc. indifference point, 24s delay	0.5	0.5	1.2	-0.2	-0.5	-1.1	0.6
Delay disc. indifference point, 4s delay	0.3	0.3	0.6	0.8	-0.8	0.1	0.3
Delay disc. indifference point, 8s delay	0.4	0.4	0.6	0.6	-0.8	-0.2	0.8
Delay discount exponential model param	0.1	0.2	0.3	-0.2	0.5	0.5	-0.3
Delay discount hyperbolic model param	0.1	0.1	0.3	-0.2	0.5	0.4	-0.3
Fecal boli incidents, locomotor time 1	0.4	0.5	0.7	0.8	-0.8	0.1	0.7
Change in fecal boli incidents, locomotor task	0.0	0.0	0.0	-0.1	0.0	-0.2	-0.0
Time >=10cm from walls, locomotor time 1	0.7	0.7	1.5	1.2	-0.8	0.8	0.2
Bouts of movement, locomotor time 1	2.2	2.4	5.3	0.1	-1.6	-2.3	1.3
Total resting periods, locomotor time 1	2.2	2.4	4.3	0.4	-1.9	-2.1	1.3
Rest time, locomotor task time 1	0.3	0.4	0.8	0.4	-0.9	-0.6	0.3
Distance moved, locomotor task time 1	0.0	0.0	0.0	0.0	0.1	0.0	-0.0
Vertical activity count, locomotor time 1	0.1	0.2	0.3	-0.3	0.5	0.4	-0.3
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.4	0.3	-0.0	0.6	0.2
Bouts of movement, locomotor time 2	1.3	1.4	2.6	1.2	-1.6	-0.4	1.2
Total resting periods, locomotor time 2	1.8	1.9	3.5	1.6	-1.9	-0.3	1.3
Rest time, locomotor task time 2	0.9	1.0	2.0	1.2	-1.4	-0.4	0.7
Distance moved, locomotor task time 2	0.8	0.9	1.8	-1.4	1.1	-0.5	-0.6
Vertical activity count, locomotor time 2	1.0	1.1	2.0	-1.4	1.4	-0.0	-0.7
Weight adjusted by age	4.1	4.6	7.0	-1.1	2.4	2.2	-2.6
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.4	-0.3	0.1	-0.7	0.1
Locomotion in novel chamber	0.2	0.3	0.9	0.4	0.1	1.0	0.2
Locomotion in novel chamber post-restriction	0.8	0.9	1.9	1.1	-0.4	1.4	-0.6
Progressive ratio	3.1	3.6	6.9	-0.5	-1.2	-2.6	2.5
Food seeking constrained by brief footshock	2.1	2.6	4.7	-2.0	2.2	-0.0	-1.3
Seeking ratio, punishment vs. effort	3.8	4.7	8.7	-0.7	2.1	2.2	-2.9
Run reversals in cocaine runway, females	0.8	0.8	1.2	-0.4	1.0	1.1	-0.9
Run reversals in cocaine runway, males	1.0	0.9	1.7	-0.1	0.9	1.1	-1.3
Latency to leave start box in cocaine runway	0.6	0.7	1.8	-0.1	-0.8	-1.4	0.4
Latency to leave start box in cocaine runway, F	1.5	1.6	3.2	0.3	-1.5	-1.8	0.9
Latency to leave start box in cocaine runway, M	1.0	0.9	1.5	-1.2	1.1	-0.1	-1.0
Cd content in liver	0.1	0.2	0.3	0.1	0.4	0.5	-0.5
Co content in liver	0.7	0.8	1.7	0.1	0.5	1.3	-1.1
Cu content in liver	0.6	0.8	1.8	0.7	0.0	1.3	-0.9
Fe content in liver	0.3	0.3	0.5	-0.5	0.7	0.4	-0.6
K content in liver	0.1	0.1	0.2	0.2	-0.2	0.1	-0.4
Mg content in liver	0.5	0.5	1.1	0.2	0.3	0.9	-1.1
Mn content in liver	0.6	0.7	1.6	0.6	0.1	1.3	-1.0
Na content in liver	0.2	0.2	0.5	-0.7	0.3	-0.5	-0.4
Rb content in liver	1.7	2.1	4.2	0.0	1.1	1.7	-2.0
Se content in liver	1.6	2.0	3.2	-0.7	1.6	1.3	-1.8
Sr content in liver	0.7	0.6	2.3	0.4	0.2	1.5	0.1
Zn content in liver	0.8	0.8	1.5	-0.9	0.9	0.1	-1.2