Hub : Genes

Adat3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	intron excision ratio	chr7:9107126:9107359	0.16	0.1	2.9e-03	0	0	-0	0	2.1e-01	1.8e-01	4.3e-01	2.6e-01
2	Brain	intron excision ratio	chr7:9102642:9104454	0.02	0.02	7.1e-03	0.01	0.02	0.01	0.01	2.1e-02	8.8e-03	5.5e-02	2.0e-02
3	Brain	intron excision ratio	chr7:9104571:9105744	0.02	0.02	4.7e-03	0.01	0.02	0.01	0.02	1.6e-02	4.5e-03	1.3e-02	1.1e-02
4	Brain	intron excision ratio	chr7:9107126:9107359	0.26	0.14	5.4e-07	0.09	0.07	0.09	0.08	2.7e-08	7.5e-07	2.1e-08	9.5e-08
5	Brain	intron excision ratio	chr7:9108033:9113898	0.03	0.03	8.1e-04	0.02	0.03	0.03	0.02	4.2e-03	1.5e-03	7.0e-04	2.5e-03
6	Brain	intron excision ratio	chr7:9110429:9113898	0.04	0.03	4.6e-04	0.03	0.03	0.03	0.02	1.9e-03	1.3e-03	1.1e-03	2.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	3.8	12.5	22.2	0.1	4.7	-4.7	-1.0	4.7	-2.8
BMI without tail	1.5	3.1	4.9	-1.3	2.2	-2.2	-2.1	1.7	-0.1
Body weight	0.6	2.6	5.2	-0.1	2.3	-2.3	-0.7	2.0	-0.9
Epididymis fat weight	0.2	0.4	0.9	-0.6	-0.8	0.8	-0.9	-0.0	-0.3
Glucose	0.7	1.0	2.1	-0.0	1.5	-1.5	-0.4	1.3	-0.5
Heart weight	0.5	0.7	1.2	-1.1	-0.7	0.7	-1.1	-0.7	0.5
Left kidney weight	0.1	0.3	0.9	0.9	-0.1	0.1	1.0	-0.2	0.1
Right kidney weight	0.9	2.6	5.2	-0.1	-2.0	2.0	0.5	-2.3	1.5
Tail length	2.4	7.3	12.2	-1.4	-3.2	3.2	-1.2	-3.5	2.8
Length with tail	1.3	4.6	9.2	-0.0	-2.6	2.6	0.6	-3.0	2.0
Length without tail	0.4	1.0	3.4	1.5	-0.2	0.2	1.9	-0.2	-0.3
Liver weight, left	2.1	3.5	6.8	-0.1	2.0	-2.0	-0.8	2.6	-2.3
Liver weight, right	1.7	2.8	5.1	0.7	1.8	-1.8	0.3	2.3	-2.3
Parametrial fat weight	0.5	1.1	1.9	-0.8	-0.9	0.9	-0.5	-1.4	1.3
Retroperitoneal fat weight	0.2	0.8	1.6	-0.2	1.0	-1.0	-0.3	1.3	-1.1
Intraocular pressure	0.9	1.3	4.3	-2.1	-0.3	0.2	-1.9	-0.3	0.2
Extensor digitorum longus weight	2.5	10.0	18.9	-0.9	4.3	-4.3	-1.2	3.9	-2.4
Soleus weight	4.9	14.2	28.7	0.5	5.3	-5.4	-0.1	4.7	-2.5
Tibialis anterior weight	0.6	2.2	4.4	0.2	2.1	-2.1	-0.1	1.9	-0.8
Tibia length	0.7	1.9	3.7	-0.6	-1.7	1.7	-0.4	-1.9	1.4
Number of licking bursts	0.6	0.8	2.0	-1.4	-0.0	-0.0	-1.4	-0.4	0.8
Food consumed during 24 hour testing period	0.2	0.3	0.7	-0.3	0.8	-0.8	-0.1	0.2	0.5
Times rat made contact with spout	0.3	0.3	0.9	-0.9	0.4	-0.4	-0.7	0.1	0.3
Mean time between licks in bursts	2.9	4.0	6.5	-1.0	-2.6	2.5	-1.1	-2.4	1.8
Mean num. licks in bursts	0.1	0.2	0.4	0.5	0.2	-0.2	0.7	0.3	-0.4
Std. dev. time between licks in bursts	1.1	1.3	3.8	0.4	-0.9	0.9	0.4	-1.6	1.9
Water consumed over 24 hours	0.7	0.8	1.9	1.0	0.9	-0.9	1.4	0.4	-0.2
Indifference point 0 sec	0.1	0.1	0.2	0.5	0.5	-0.5	0.3	0.3	0.1
Indifference point AUC	0.6	0.7	1.2	-0.5	-1.1	1.1	-0.3	-1.0	0.4
Indifference point function ln k	0.2	0.3	1.0	-0.2	0.6	-0.6	-0.1	-0.1	1.0
Indifference point function log k	0.2	0.3	1.0	-0.2	0.6	-0.6	-0.1	-0.1	1.0
Delay discounting total patch changes 0 sec	0.1	0.1	0.2	0.3	0.4	-0.4	0.1	0.2	0.3
Delay discounting total patch changes 12 sec	0.5	0.6	1.6	-0.8	0.5	-0.5	-1.3	0.7	-0.7
Delay discounting total patch changes 18 sec	0.7	0.9	1.6	-0.3	-1.2	1.2	-0.3	-1.2	0.8
Delay discounting total patch changes 24 sec	0.0	0.0	0.1	0.1	-0.3	0.3	-0.0	0.0	-0.3
Delay discounting total patch changes 6 sec	0.1	0.2	0.4	0.2	-0.6	0.6	0.1	-0.5	0.3
Delay discounting time to switch 0 sec	3.4	5.2	10.9	2.4	1.6	-1.5	1.7	2.7	-3.3
Delay discounting water rate 0 sec	1.8	2.8	6.0	-2.4	-0.3	0.2	-1.8	-1.4	2.4
Delay discounting water rate 12 sec	1.3	2.0	4.6	-2.0	1.0	-1.1	-2.1	0.2	0.9
Delay discounting water rate 18 sec	3.9	5.1	12.2	-3.5	-0.6	0.5	-3.2	-1.4	2.3
Delay discounting water rate 24 sec	2.3	3.1	10.1	-3.2	0.3	-0.4	-2.7	-0.4	0.9
Delay discounting water rate 6 sec	2.4	3.5	6.1	-2.5	-0.8	0.7	-2.3	-1.7	2.4
Locomotor activity	2.6	4.1	7.4	1.0	-2.2	2.2	1.1	-2.7	2.3
Locomotor testing distance	1.6	2.7	4.9	0.4	-1.8	1.8	0.4	-2.2	2.1
Locomotor testing rearing	0.6	1.0	2.9	-0.9	-0.2	0.2	-1.3	-0.8	1.7
Light reinforcement 1	2.7	4.9	11.3	0.4	-3.3	3.4	0.6	-2.4	0.8
Light reinforcement 2	1.0	1.3	2.9	0.4	-1.7	1.7	0.8	-1.1	0.1
Reaction time number correct	0.8	1.2	3.0	-1.7	0.7	-0.7	-1.4	0.1	0.9
Reaction time mean minus median	0.9	1.2	2.4	-0.7	-1.0	0.9	-0.4	-1.4	1.5
Reaction time mean minus median AUC	0.3	0.4	1.0	1.0	0.1	-0.1	1.0	-0.2	0.5
Reaction time num false alarms	1.2	1.7	6.0	-1.4	0.2	-0.3	-1.2	-0.9	2.5
Reaction time num false alarms AUC	1.3	1.8	5.4	-1.7	0.3	-0.3	-1.5	-0.7	2.3
Reaction time trials correct on left	0.8	1.2	3.0	-1.7	0.7	-0.7	-1.4	0.1	0.9
Reaction time trials on left	0.7	1.1	2.7	-1.6	0.7	-0.8	-1.3	0.1	0.9
Reaction time mean	0.1	0.1	0.3	0.6	0.1	-0.1	0.6	-0.1	0.1
Reaction time mean AUC	0.1	0.2	0.4	0.6	0.2	-0.2	0.7	-0.1	0.1
Median of all reaction times	0.3	0.4	0.8	0.9	0.7	-0.7	0.7	0.5	-0.5
Reaction time omissions	0.2	0.2	0.3	0.4	-0.6	0.6	0.4	-0.4	0.4
Reaction time false alarm rate	0.3	0.4	1.9	-0.3	0.1	-0.1	-0.3	-0.5	1.4
Reaction time premature initiation rate	1.1	1.5	1.8	-1.1	-1.3	1.3	-1.1	-1.4	1.3
Reaction time premature initiations	1.8	2.6	4.4	-2.1	-1.0	1.0	-1.9	-1.4	1.8
Std. dev. reaction times	0.2	0.3	0.7	-0.1	-0.5	0.5	0.2	-0.8	0.8
Reaction time trials completed	0.7	1.1	2.7	-1.6	0.7	-0.8	-1.3	0.1	0.9
Reaction time trials AUC	1.0	1.4	3.8	-1.9	0.6	-0.7	-1.6	-0.0	1.0
Social response proportion	0.8	0.9	1.9	0.9	-0.8	0.8	1.1	-0.0	-1.4
Social responses	4.3	5.6	10.9	0.4	-2.9	3.0	1.0	-3.3	2.0
Social time	1.0	1.4	4.0	0.5	0.9	-0.9	-0.3	1.5	-2.0
Conditioned locomotion	1.1	1.3	2.3	-1.3	1.2	-1.2	-1.5	1.0	-0.2
Cocaine response after cond. corrected	2.8	3.1	5.6	-1.7	2.3	-2.4	-1.6	1.5	-0.3
Cocaine response after cond. not corrected	3.0	3.3	5.8	-1.8	2.3	-2.4	-1.7	1.6	-0.4
Cocaine response before conditioning	0.3	0.4	0.5	0.2	-0.7	0.7	0.4	-0.7	0.7
Saline control response	0.1	0.1	0.4	-0.2	0.2	-0.2	-0.6	0.3	-0.3
Condit. Reinf. active minus inactive responses	2.6	3.2	5.4	-1.5	-1.8	1.8	-0.9	-2.3	2.1
Condit. Reinf. active-inactive response ratio	0.9	1.0	2.5	-1.6	-0.5	0.4	-1.6	-0.6	0.5
Condit. Reinf. active responses	2.3	3.3	6.7	-1.0	-1.8	1.8	-0.1	-2.6	2.3
Condit. Reinf. inactive responses	1.3	1.6	3.7	-0.2	-1.1	1.1	0.8	-1.9	1.6
Condit. Reinf. lever presses	2.3	3.1	4.7	-1.4	-1.9	1.9	-1.1	-2.2	2.0
Condit. Reinf. lever reinforcers received	2.2	3.0	5.9	-1.4	-1.6	1.6	-0.5	-2.4	2.3
Pavlov. Cond. lever latency	1.1	1.6	3.6	0.5	1.0	-1.0	-0.1	1.9	-1.9
Pavlov. Cond. magazine entry latency	0.6	0.7	1.8	-0.2	-0.7	0.7	-0.1	-1.1	1.3
Pavlov. Cond. change in total contacts	1.0	1.4	2.9	-0.7	-1.0	1.0	-0.3	-1.7	1.7
Pavlov. Cond. index score	1.4	1.8	4.7	-0.7	-1.1	1.1	-0.4	-1.9	2.2
Pavlov. Cond. latency score	1.2	1.5	3.9	-0.4	-1.0	1.0	-0.1	-1.8	2.0
Pavlov. Cond. lever contacts	1.3	1.8	4.1	-1.0	-1.0	1.0	-0.5	-1.8	2.0
Pavlov. Cond. magazine entry number	1.0	1.2	3.5	0.2	0.9	-0.9	0.2	1.5	-1.9
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.6	-0.8	0.5	-0.5	-0.7	0.4	-0.2
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.7	4.2	-0.5	-1.1	1.0	-0.2	-1.8	2.1
Pavlov. Cond. response bias	2.3	3.2	6.6	-1.2	-1.6	1.6	-0.7	-2.4	2.6
Conditioned reinforcement - actives	2.1	2.0	4.1	-0.4	-1.6	1.6	0.1	-2.0	1.7
Conditioned reinforcement - inactives	0.3	0.3	0.5	-0.7	0.7	-0.7	-0.3	0.5	-0.4
Conditioned locomotion	5.2	6.2	11.1	-0.7	-3.1	3.1	-0.0	-3.3	2.5
Intermittent access intake day 1-15 change	5.4	5.4	9.6	-1.1	-2.7	2.7	-0.6	-3.1	2.5
Intermittent access intake escalation	6.5	6.4	10.1	-2.0	-2.7	2.7	-1.6	-3.2	2.7
Intermittent access intake escalation 2	7.6	7.6	11.3	-2.1	-3.0	3.0	-1.9	-3.4	2.9
Intermitt. access day 1 inactive lever presses	1.0	1.1	1.8	-1.4	-0.6	0.5	-0.8	-1.3	1.3
Intermitt. access day 15 inactive lever presses	0.4	0.5	0.8	-0.6	-0.8	0.8	-0.2	-0.9	0.6
Intermitt. access escalation Index	0.9	0.8	1.9	1.4	0.5	-0.5	1.4	0.6	-0.5
Intermittent access day 1 total infusions	0.0	0.0	0.1	0.2	0.2	-0.2	0.4	0.0	-0.0
Intermittent access day 15 total infusions	2.0	2.3	4.0	-1.1	-1.6	1.6	-0.7	-2.0	1.7
Intermittent access terminal intake (last 3 days)	1.3	1.4	2.9	-0.7	-1.2	1.1	-0.3	-1.7	1.5
Intermittent access total infusions	0.3	0.4	0.8	-0.6	-0.5	0.5	-0.2	-0.9	0.8
Intermittent access day 1 locomotion	0.3	0.3	0.4	-0.4	-0.7	0.7	0.0	-0.7	0.4
Intermittent access day 15 total locomotion	2.3	2.5	4.3	-0.7	-2.1	2.1	-0.3	-2.0	1.4
Intermittent access total locomotion	0.7	0.8	1.6	-0.2	-1.1	1.1	0.2	-1.3	0.9
Intermittent access standard deviation	2.8	3.0	5.7	-1.3	-1.9	1.8	-0.6	-2.4	1.8
Cocaine induced anxiety	0.6	0.7	1.5	1.2	-0.7	0.7	1.2	-0.5	-0.2
Post-drug Anxiety	0.7	0.7	1.9	1.4	-0.5	0.5	1.2	0.1	-0.8
Baseline Anxiety	0.4	0.4	1.1	-0.9	-0.3	0.3	-1.0	-0.2	0.4
Lifetime Intake	0.1	0.1	0.4	-0.3	-0.3	0.3	0.1	-0.6	0.4
Incentive Sensitization - Responses	0.9	0.9	1.5	-1.1	-0.5	0.5	-1.0	-1.1	1.2
Incentive Sensitization - Breakpoint	0.8	0.8	1.3	-1.0	-0.5	0.5	-0.8	-1.1	1.1
Progressive ratio test 1 active lever presses	0.1	0.1	0.4	-0.6	0.2	-0.2	-0.2	0.1	-0.0
Progressive ratio test 1 breakpoint	0.1	0.1	0.3	-0.5	0.3	-0.3	-0.1	0.2	-0.1
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.3	0.0	-0.1	0.1	0.5	-0.1	-0.1
Progressive ratio test 2 active lever presses	0.6	0.7	1.1	-1.1	-0.5	0.5	-0.7	-1.0	1.0
Progressive ratio test 2 breakpoint	0.4	0.5	1.0	-0.6	-0.5	0.5	-0.2	-1.0	0.9
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	0.1	-0.2	0.2	0.3	-0.4	0.2
Total sessions with >9 infusions	0.2	0.2	0.8	0.4	0.1	-0.1	0.9	-0.5	0.4
Short access day 1 total inactive lever presses	0.1	0.1	0.4	0.1	-0.2	0.3	0.6	0.0	-0.5
Short access day 10 total inactive lever presses	0.1	0.1	0.4	-0.6	-0.2	0.2	-0.5	-0.4	0.2
Short access day 1 total infusions	0.4	0.4	1.6	0.8	-0.3	0.3	1.3	-0.2	-0.1
Short access day 10 total infusions	0.1	0.1	0.4	-0.6	-0.2	0.2	0.2	-0.5	0.3
Short access total infusions	0.0	0.1	0.2	0.1	0.0	-0.0	0.5	-0.2	0.1
Short access day 1 locomotion	1.0	1.0	1.8	0.4	-1.0	1.0	1.1	-1.3	0.9
Short access day 10 total locomotion	3.7	4.0	7.7	-1.1	-2.3	2.2	-0.1	-2.8	2.2
Short access total locomotion	1.0	1.0	2.2	-0.1	-1.0	1.0	0.6	-1.5	1.2
Compulsive drug intake	1.1	1.1	1.4	0.9	1.2	-1.2	0.6	1.2	-0.9
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.1	0.4	-0.4	0.4	0.2	-0.3
One hour access (shock baseline)	0.3	0.3	0.9	-1.0	-0.4	0.3	-0.2	-0.6	0.5
Number of responses in last shaping day	0.4	0.4	1.0	-0.3	-0.4	0.4	0.4	-1.0	0.7
Context. condit. distance diff. score	0.2	0.2	0.3	-0.2	0.6	-0.6	-0.3	0.5	0.3
Locomotion velocity, session 1	0.7	0.8	1.8	1.3	-0.6	0.6	1.3	-0.3	-0.6
Locomotion distance, session 1	2.1	2.7	6.2	2.5	-0.1	0.2	2.1	0.9	-2.2
Locomotion velocity, session 2	2.5	2.9	4.5	2.0	-1.8	1.9	2.1	-0.8	-1.1
Locomotion distance, session 2	2.2	3.2	6.3	2.5	-1.2	1.3	2.4	-0.2	-2.0
Locomotion velocity, session 3	3.9	4.6	7.7	-0.8	-2.8	2.8	-0.4	-2.6	2.1
Locomotion distance, session 3	0.0	0.0	0.2	-0.4	0.0	-0.0	-0.3	-0.1	0.1
Stereotopy head waving bouts, day 3	2.3	2.8	5.9	0.6	-2.4	2.4	0.5	-1.8	1.3
Stereotopy head waving duration, day 3	3.0	3.6	7.2	0.2	-2.7	2.7	0.1	-2.2	1.7
Locomotion velocity, session 7	1.3	1.4	3.6	-0.5	-0.8	0.8	0.1	-1.8	1.9
Locomotion distance, session 7	0.4	0.5	1.7	-1.3	0.3	-0.3	-0.9	-0.4	0.3
Stereotopy head waving bouts, day 7	0.6	0.7	2.0	1.4	0.1	-0.1	1.3	0.4	-0.1
Stereotopy head waving duration, day 7	0.6	0.8	2.3	1.5	-0.3	0.3	1.4	-0.1	0.3
Locomotion velocity, session 8	1.3	1.6	4.2	2.1	-0.5	0.6	2.0	-0.1	-0.7
Locomotion distance, session 8	0.3	0.4	0.9	1.0	-0.3	0.3	0.7	0.3	-0.8
Degree of sensitization distance	0.2	0.2	0.4	0.1	0.6	-0.7	0.1	0.4	-0.4
Degree of sensitization stereotypy	1.7	1.8	2.4	1.2	1.5	-1.5	1.3	1.4	-1.0
Condit. Reinf. active minus inactive responses	2.1	2.4	5.0	-0.2	-2.2	2.2	0.3	-1.8	1.0
Condit. Reinf. active-inactive response ratio	1.6	1.7	2.7	-1.1	-1.6	1.6	-0.4	-1.6	1.1
Condit. Reinf. active responses	1.7	2.1	4.4	0.9	-2.1	2.1	1.1	-1.4	0.3
Condit. Reinf. inactive responses	0.9	1.1	2.9	1.7	-0.8	0.9	1.4	-0.2	-0.6
Incentive salience index mean	1.1	1.3	2.6	0.8	-1.6	1.6	1.0	-1.0	0.2
Condit. Reinf. lever presses	1.5	2.0	5.6	2.4	0.1	-0.1	2.0	0.8	-1.2
Time in familiar zone, hab. session 1	2.3	2.2	3.4	-1.0	-1.5	1.5	-1.0	-1.7	1.9
Time in novel zone, hab. session 1	1.6	1.5	2.8	1.3	1.1	-1.1	1.7	1.0	-1.2
Total zone transitions, hab. session 1	1.2	1.6	3.2	1.8	-0.9	1.0	1.8	-0.3	-1.3
Total locomotion distance, hab. session 1	1.9	2.7	6.8	2.5	-0.9	1.0	2.6	-0.5	-1.1
Locomotion velocity, hab. session 1	1.6	2.3	4.8	2.2	-1.2	1.3	2.1	-0.5	-1.1
Time in familiar zone, hab. session 2	5.2	5.4	7.4	-1.7	-2.7	2.7	-1.5	-2.6	2.4
Time in novel zone, hab. session 2	3.6	3.6	5.5	1.5	2.3	-2.3	1.5	2.0	-1.5
Total zone transitions, hab. session 2	4.1	5.3	13.6	2.9	0.6	-0.5	2.5	1.8	-3.7
Total locomotion distance, hab. session 2	1.5	2.0	3.7	1.9	-0.9	1.0	1.7	0.2	-1.9
Locomotion velocity, hab. session 2	2.2	3.0	5.8	2.4	-0.9	0.9	2.1	0.4	-2.4
Novel to familiar place preference ratio	3.8	4.0	5.0	1.9	2.2	-2.2	1.7	2.1	-1.8
Novelty place preference	2.7	2.8	3.1	1.7	1.8	-1.7	1.6	1.7	-1.5
Time in novel zone, NPP test	2.7	2.8	3.5	1.6	1.9	-1.8	1.5	1.7	-1.5
Total zone transitions, NPP test	2.1	3.0	10.0	2.0	0.1	-0.1	1.4	1.4	-3.2
Total locomotion distance, NPP test	1.8	2.5	6.1	2.1	0.3	-0.2	1.7	1.2	-2.5
Locomotion velocity, NPP test	1.6	2.2	5.6	2.0	-0.0	0.1	1.7	1.0	-2.4
Pavlov. Cond. lever latency	0.6	0.8	2.2	-1.5	-0.2	0.2	-1.4	-0.4	0.6
Pavlov. Cond. magazine entry latency	1.5	2.0	4.2	-0.5	-2.0	2.1	-0.5	-1.5	1.0
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.3	-0.2	0.2	0.1	0.0	-0.0
Pavlov. Cond. index score	0.3	0.3	0.7	0.8	-0.6	0.7	0.7	-0.2	-0.0
Pavlov. Cond. latency score	0.5	0.6	1.6	1.3	-0.6	0.6	1.1	-0.1	-0.1
Pavlov. Cond. lever contacts	0.8	1.0	2.9	1.7	0.0	0.0	1.7	0.3	-0.5
Pavlov. Cond. magazine entry number	0.3	0.4	0.9	-0.0	1.0	-1.0	0.1	0.4	-0.2
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.4	-1.2	-0.5	0.4	-0.9	-0.5	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.9	0.7	-0.9	0.9	0.6	-0.5	0.3
Pavlov. Cond. response bias	0.5	0.6	1.4	0.0	-1.2	1.2	0.2	-0.7	0.3
Bone: apparent density	1.4	2.3	6.9	2.6	0.4	-0.3	2.6	0.2	-0.2
Bone surface	2.5	4.4	13.3	3.6	-0.1	0.2	3.6	-0.2	0.1
Bone volume	2.6	4.4	13.3	3.5	-0.1	0.2	3.7	-0.5	0.5
Bone: connectivity density	1.1	1.8	4.6	2.1	0.8	-0.7	1.9	0.9	-0.8
Bone: cortical apparent density	0.5	0.6	1.0	0.2	1.0	-1.0	0.0	0.9	-0.8
Bone: cortical area	0.6	1.0	1.9	1.3	1.0	-1.0	1.4	0.4	-0.0
Bone: cortical porosity	0.5	0.6	1.1	0.7	-0.7	0.7	1.0	-0.8	0.5
Bone: cortical porosity	0.8	0.9	2.9	1.5	0.0	0.0	1.7	0.0	-0.3
Bone: cortical thickness	0.8	1.3	2.1	0.9	1.4	-1.4	0.9	1.2	-0.9
Bone: cortical thickness	0.6	0.8	1.9	-1.4	-0.1	0.1	-1.1	-0.7	1.0
Bone: cortical tissue density	0.3	0.4	0.7	0.1	0.8	-0.8	-0.0	0.8	-0.7
Bone: elastic displacement	0.4	0.4	0.9	0.1	-0.5	0.5	0.4	-0.9	0.9
Bone: elastic work	0.3	0.4	0.7	0.4	0.6	-0.6	0.8	-0.4	0.8
Bone: endosteal estimation	0.2	0.4	0.7	0.6	0.7	-0.7	0.8	0.2	0.2
Bone: endosteal perimeter	0.3	0.6	1.2	0.8	-0.6	0.6	0.8	-0.9	1.1
Bone: final force	0.9	1.5	2.5	1.0	1.6	-1.6	1.5	0.7	-0.3
Bone: final moment	0.7	1.2	2.1	1.0	1.4	-1.4	1.5	0.6	-0.3
Bone: marrow area	0.2	0.4	0.6	0.6	0.7	-0.7	0.8	0.3	0.2
Bone: maximum diameter	0.7	1.3	2.1	1.2	-1.0	1.0	1.4	-1.2	1.0
Bone: maximum force	0.7	1.2	2.5	0.7	1.6	-1.6	1.2	0.6	-0.2
Bone: maximum moment	0.6	1.0	2.0	0.7	1.4	-1.4	1.2	0.5	-0.2
Bone: minimum diameter	0.2	0.3	0.7	0.7	0.2	-0.2	0.8	-0.3	0.7
Bone: periosteal estimation	0.5	1.0	2.6	1.4	0.9	-0.9	1.6	0.3	0.1
Bone: periosteal perimeter	0.4	0.7	1.7	1.2	-0.1	0.1	1.3	-0.6	0.8
Bone: post-yield work	0.2	0.3	0.8	-0.2	0.9	-0.9	-0.1	0.5	-0.3
Bone: stiffness	1.7	2.8	5.4	0.9	2.3	-2.3	0.8	1.8	-1.1
Bone: tissue strength	1.4	1.3	1.9	0.7	1.4	-1.3	0.5	1.3	-1.4
Bone: trabecular number	0.8	1.3	3.5	1.5	-0.8	0.8	1.9	-0.7	0.1
Bone: trabecular spacing	2.1	2.6	8.0	-2.7	0.4	-0.5	-2.8	0.1	0.6
Bone: trabecular thickness	3.2	3.9	12.2	3.5	0.4	-0.3	3.3	0.0	-0.0
Bone: trabecular tissue density	1.1	1.6	2.7	-0.4	1.5	-1.5	-0.8	1.6	-1.2
Breakpoint value in progressive ratio session	4.5	5.0	6.9	-1.2	-2.6	2.6	-1.4	-2.6	2.5
Distance traveled before self-admin	0.5	0.5	0.8	0.6	0.7	-0.7	0.9	0.6	-0.7
Distance traveled after self-admin	0.4	0.5	1.0	0.2	-0.8	0.8	0.2	-1.0	0.6
Delta time in closed arm before/after self-admin	2.0	1.9	5.4	-2.3	0.6	-0.6	-2.3	0.1	0.5
Delta time in open arm before/after self-admin	1.4	1.3	2.1	0.8	1.2	-1.1	0.8	1.4	-1.5
Diff in mean of infusions in LGA sessions	1.0	1.1	2.2	-0.2	-1.5	1.5	-0.4	-1.1	0.9
Extinction: sum of active levers before priming	1.8	1.9	2.6	-1.4	-1.3	1.2	-1.6	-1.3	1.4
Active lever presses in extinction session 6	2.3	2.2	4.1	-0.1	-1.7	1.7	-0.2	-2.0	1.7
Delta distance traveled before/after self-admin	1.1	1.1	1.9	-0.1	-1.4	1.4	-0.3	-1.3	1.1
Delta ambulatory time before/after self-admin	1.0	1.1	2.0	0.1	-1.4	1.4	0.1	-1.3	0.8
Time in closed arm before self-admin	2.1	2.4	3.7	1.9	1.0	-1.0	1.8	1.5	-1.9
Time in closed arm after self-admin	0.0	0.0	0.1	-0.2	-0.1	0.1	-0.3	0.0	0.1
Time in open arm before self-admin	1.5	1.6	4.1	-0.8	-1.0	1.0	-0.8	-1.5	2.0
Time in open arm after self-admin	0.3	0.4	0.8	0.0	0.9	-0.9	-0.0	0.7	-0.3
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.1	-0.0	0.0	-0.0	0.0	-0.3
Time to tail flick, vehicle, before self-admin	0.8	0.8	2.5	1.1	-0.5	0.6	1.6	-0.3	-0.3
Time to tail flick, vehicle, after self-admin	0.8	0.8	2.0	-1.4	-0.4	0.4	-1.4	-0.3	0.7
Time to tail flick, test, before self-admin	0.5	0.5	1.6	1.1	-0.3	0.3	1.3	-0.2	-0.2
Time to tail flick, test, after self-admin	0.4	0.4	1.2	0.6	-0.4	0.4	1.1	-0.0	-0.5
Delta time to tail flick, vehicle, before/after SA	1.4	1.3	4.2	-1.7	0.4	-0.5	-2.1	0.3	0.6
Delta time to tail flick, test, before/after SA	0.3	0.3	0.8	-0.9	-0.4	0.4	-0.5	-0.3	0.0
Ambulatory time before self-admin	0.3	0.3	0.4	0.5	0.6	-0.6	0.5	0.4	-0.5
Ambulatory time after self-admin	0.2	0.2	0.5	0.2	-0.6	0.6	0.3	-0.7	0.2
Total heroin consumption	1.4	1.7	2.5	-0.2	-1.6	1.6	-0.3	-1.6	1.6
Area under the delay curve	1.2	1.3	2.8	0.5	1.7	-1.7	0.5	1.2	-0.5
Delay disc. indifference point, 0s delay	8.0	8.7	11.4	2.7	3.0	-2.9	2.2	3.4	-3.3
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	0.2	0.4	-0.4	-0.1	0.4	0.2
Delay disc. indifference point, 2s delay	4.0	4.5	7.2	1.3	2.7	-2.7	1.1	2.5	-1.7
Delay disc. indifference point, 24s delay	0.5	0.5	0.7	-0.2	0.8	-0.9	-0.9	0.5	0.7
Delay disc. indifference point, 4s delay	0.8	0.9	1.4	0.9	1.2	-1.2	0.8	1.0	-0.0
Delay disc. indifference point, 8s delay	0.5	0.6	1.4	-0.6	1.1	-1.2	-0.1	0.5	-0.3
Delay discount exponential model param	1.0	1.1	2.5	-0.3	-1.6	1.6	-0.3	-1.1	0.3
Delay discount hyperbolic model param	1.5	1.6	3.6	-0.5	-1.9	1.9	-0.5	-1.4	0.4
Fecal boli incidents, locomotor time 1	1.5	1.6	3.6	-0.4	1.3	-1.4	-0.3	1.5	-1.9
Change in fecal boli incidents, locomotor task	1.2	1.2	4.0	0.4	-0.3	0.3	0.7	-1.5	2.0
Time >=10cm from walls, locomotor time 1	0.5	0.5	1.3	1.1	0.7	-0.7	0.8	0.3	-0.4
Bouts of movement, locomotor time 1	0.1	0.2	0.4	-0.5	-0.4	0.4	-0.1	-0.6	0.1
Total resting periods, locomotor time 1	0.2	0.2	0.5	-0.3	-0.5	0.5	0.0	-0.7	0.4
Rest time, locomotor task time 1	0.1	0.1	0.2	0.3	-0.5	0.5	0.3	-0.3	0.1
Distance moved, locomotor task time 1	0.5	0.6	1.5	1.2	0.8	-0.8	0.6	0.5	0.3
Vertical activity count, locomotor time 1	0.7	0.7	2.4	-0.8	0.3	-0.3	-0.6	-0.8	1.5
Time >=10cm from walls, locomotor time 2	0.6	0.6	1.4	-0.6	1.1	-1.2	-0.6	0.4	-0.0
Bouts of movement, locomotor time 2	0.8	0.9	2.2	1.3	-0.6	0.6	1.5	0.1	-0.8
Total resting periods, locomotor time 2	0.8	0.9	2.2	1.4	-0.5	0.5	1.5	0.1	-0.7
Rest time, locomotor task time 2	0.3	0.4	0.6	0.7	-0.7	0.7	0.7	-0.5	0.2
Distance moved, locomotor task time 2	0.5	0.5	0.8	-0.4	0.9	-0.9	-0.9	0.8	-0.3
Vertical activity count, locomotor time 2	0.7	0.7	1.6	-1.3	0.8	-0.8	-1.2	0.3	0.0
Weight adjusted by age	0.7	0.8	2.0	-1.4	0.5	-0.5	-1.2	-0.1	0.7
Seeking ratio, delayed vs. immediate footshock	3.1	3.5	6.2	0.2	-2.3	2.3	0.5	-2.5	2.0
Locomotion in novel chamber	0.5	0.6	0.8	-0.8	-0.6	0.6	-0.7	-0.9	0.9
Locomotion in novel chamber post-restriction	1.6	1.9	6.1	-0.7	-1.0	1.0	-0.5	-1.5	2.5
Progressive ratio	0.8	1.0	3.9	-0.2	0.4	-0.4	-0.5	1.2	-2.0
Food seeking constrained by brief footshock	0.4	0.5	1.8	0.6	-0.4	0.4	-0.0	0.7	-1.4
Seeking ratio, punishment vs. effort	0.2	0.2	0.4	0.6	-0.4	0.5	0.5	-0.2	0.3
Run reversals in cocaine runway, females	0.4	0.4	0.7	0.2	-0.6	0.6	0.3	-0.8	0.8
Run reversals in cocaine runway, males	0.6	0.6	1.3	0.4	-1.1	1.2	0.5	-0.7	0.3
Latency to leave start box in cocaine runway	1.3	1.4	3.1	1.2	-0.8	0.9	0.8	-1.4	1.7
Latency to leave start box in cocaine runway, F	1.0	1.1	3.9	2.0	0.2	-0.2	1.6	-0.3	0.3
Latency to leave start box in cocaine runway, M	3.8	3.6	5.9	-1.6	-1.8	1.8	-1.6	-2.1	2.4
Cd content in liver	0.2	0.2	0.3	0.3	0.5	-0.5	0.5	0.3	-0.6
Co content in liver	0.4	0.4	0.7	-0.5	-0.8	0.8	-0.4	-0.8	0.5
Cu content in liver	0.7	0.9	2.2	1.3	0.4	-0.4	1.5	0.3	-1.0
Fe content in liver	0.1	0.1	0.4	-0.6	-0.2	0.2	-0.5	-0.0	-0.4
K content in liver	0.8	0.8	2.1	1.5	0.2	-0.1	1.1	0.5	-0.9
Mg content in liver	0.7	0.8	2.3	1.5	0.2	-0.2	1.2	0.4	-0.7
Mn content in liver	1.9	2.2	6.2	2.3	-0.7	0.8	2.5	-0.8	0.1
Na content in liver	1.9	2.1	3.5	1.5	1.1	-1.1	1.3	1.5	-1.9
Rb content in liver	1.1	1.4	2.8	1.7	0.8	-0.8	1.7	0.9	-1.0
Se content in liver	0.1	0.1	0.3	0.2	-0.4	0.4	0.5	-0.2	-0.4
Sr content in liver	0.5	0.4	1.5	-1.2	-0.2	0.1	-1.0	-0.2	0.4
Zn content in liver	2.8	3.1	5.2	-2.3	-1.6	1.6	-2.0	-1.5	1.5