Hub : Genes

ENSRNOG00000062516

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000062516	0.05	0.03	5.4e-03	0.02	0.01	0	0.01	9.3e-04	2.7e-02	1.4e-01	6.9e-03
2	NAcc	gene expression	ENSRNOG00000062516	0.19	0.09	1.5e-04	0.03	0.04	0.05	0.04	2.3e-03	4.4e-04	2.5e-04	3.5e-04
3	PL	gene expression	ENSRNOG00000062516	0.03	0.02	5.7e-03	0.03	0.03	0.02	0.02	2.3e-03	3.9e-03	1.8e-02	1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.7	2.3	4.7	1.4	2.2	0.1
BMI without tail	1.2	2.5	4.6	0.2	1.7	2.1
Body weight	1.1	4.8	10.0	-2.0	-0.5	3.2
Epididymis fat weight	0.5	1.2	2.2	0.1	1.2	1.5
Glucose	0.6	0.9	2.4	0.6	0.1	-1.5
Heart weight	0.1	0.2	0.3	-0.5	-0.4	-0.1
Left kidney weight	0.2	0.7	1.9	-0.1	-1.4	-0.4
Right kidney weight	0.4	1.3	3.4	-0.5	-1.8	0.4
Tail length	1.7	5.3	10.5	-2.1	-0.9	3.2
Length with tail	2.6	9.6	11.0	-3.3	-2.7	3.2
Length without tail	1.2	2.6	4.5	-1.6	-2.1	0.7
Liver weight, left	1.8	2.9	4.3	-2.1	-1.8	1.1
Liver weight, right	0.6	1.0	2.8	-0.5	-1.7	-0.3
Parametrial fat weight	1.1	2.2	5.0	-0.8	-1.0	2.2
Retroperitoneal fat weight	0.8	2.5	6.8	-0.8	0.0	2.6
Intraocular pressure	0.7	1.0	1.9	0.5	1.4	1.0
Extensor digitorum longus weight	4.1	16.4	26.0	4.2	5.1	-2.3
Soleus weight	0.2	0.6	0.8	-0.8	-0.6	0.9
Tibialis anterior weight	1.3	4.3	10.0	1.7	3.2	0.3
Tibia length	1.1	3.2	7.0	-1.4	-2.6	0.8
Number of licking bursts	0.5	0.6	1.0	-0.9	-1.0	-0.3
Food consumed during 24 hour testing period	1.8	2.2	5.3	-0.6	0.9	2.3
Times rat made contact with spout	1.1	1.2	2.8	-0.8	-0.4	1.7
Mean time between licks in bursts	0.2	0.3	0.4	-0.6	-0.5	0.6
Mean num. licks in bursts	0.8	1.0	1.8	0.5	1.0	1.3
Std. dev. time between licks in bursts	0.4	0.5	1.0	0.6	1.0	-0.1
Water consumed over 24 hours	0.2	0.3	0.8	0.0	0.1	0.9
Indifference point 0 sec	2.5	4.0	7.4	-2.1	-0.6	2.7
Indifference point AUC	0.7	0.8	1.6	-0.9	0.1	1.2
Indifference point function ln k	0.2	0.2	0.2	0.5	-0.5	-0.5
Indifference point function log k	0.2	0.2	0.2	0.5	-0.5	-0.5
Delay discounting total patch changes 0 sec	2.9	4.8	8.4	-2.3	-0.8	2.9
Delay discounting total patch changes 12 sec	3.2	4.3	6.3	-2.5	-0.7	2.4
Delay discounting total patch changes 18 sec	1.4	1.9	3.7	-1.4	-0.2	1.9
Delay discounting total patch changes 24 sec	3.6	4.6	6.6	-2.3	-1.4	2.6
Delay discounting total patch changes 6 sec	1.5	2.3	4.2	-1.6	-0.6	2.0
Delay discounting time to switch 0 sec	0.3	0.5	0.8	0.9	0.5	-0.7
Delay discounting water rate 0 sec	1.1	1.7	4.5	-0.8	0.1	2.1
Delay discounting water rate 12 sec	0.4	0.6	1.0	0.4	-1.0	-0.7
Delay discounting water rate 18 sec	0.8	1.1	2.7	-0.8	-1.6	0.2
Delay discounting water rate 24 sec	0.6	0.9	1.7	-0.9	-1.3	0.0
Delay discounting water rate 6 sec	0.2	0.2	0.6	-0.1	-0.8	0.3
Locomotor activity	0.3	0.5	1.3	-0.4	0.0	1.2
Locomotor testing distance	0.8	1.4	3.5	-0.5	0.7	1.9
Locomotor testing rearing	0.9	1.4	2.9	0.6	1.7	1.0
Light reinforcement 1	0.1	0.2	0.4	0.1	0.7	0.4
Light reinforcement 2	0.2	0.3	0.7	-0.2	0.1	0.8
Reaction time number correct	0.6	0.8	2.3	-0.3	-1.5	-0.4
Reaction time mean minus median	0.7	1.0	1.4	0.9	1.2	-0.8
Reaction time mean minus median AUC	0.4	0.6	1.5	0.4	0.0	-1.2
Reaction time num false alarms	3.0	4.1	5.6	-2.4	-1.7	2.0
Reaction time num false alarms AUC	3.4	4.7	6.3	-2.5	-1.8	2.2
Reaction time trials correct on left	0.6	0.8	2.3	-0.3	-1.5	-0.4
Reaction time trials on left	0.6	0.9	2.4	-0.4	-1.5	-0.4
Reaction time mean	0.6	0.8	2.2	0.3	0.2	-1.5
Reaction time mean AUC	0.9	1.2	2.9	0.7	0.6	-1.7
Median of all reaction times	0.5	0.7	2.1	0.2	-0.0	-1.5
Reaction time omissions	0.0	0.0	0.1	-0.0	-0.3	0.0
Reaction time false alarm rate	1.8	2.6	3.6	-1.9	-0.7	1.9
Reaction time premature initiation rate	0.5	0.7	1.9	0.2	0.4	1.4
Reaction time premature initiations	0.4	0.6	1.4	-0.2	-0.5	1.2
Std. dev. reaction times	0.5	0.6	0.9	0.6	0.8	-1.0
Reaction time trials completed	0.6	0.9	2.4	-0.4	-1.5	-0.4
Reaction time trials AUC	0.6	0.8	2.2	-0.4	-1.5	-0.4
Social response proportion	0.1	0.1	0.2	0.2	0.1	-0.4
Social responses	0.0	0.1	0.1	-0.1	-0.1	0.4
Social time	0.0	0.0	0.1	0.0	-0.2	0.3
Conditioned locomotion	0.2	0.2	0.5	-0.2	0.7	0.3
Cocaine response after cond. corrected	0.6	0.6	1.7	-0.4	-1.3	-0.3
Cocaine response after cond. not corrected	1.4	1.5	4.0	-0.6	-2.0	-0.4
Cocaine response before conditioning	0.4	0.4	1.1	-0.4	-1.0	-0.3
Saline control response	1.0	1.3	3.1	0.2	1.8	0.9
Condit. Reinf. active minus inactive responses	8.9	11.0	13.5	-3.7	-3.2	3.0
Condit. Reinf. active-inactive response ratio	4.5	4.7	5.6	-2.4	-2.1	2.0
Condit. Reinf. active responses	6.4	8.9	11.1	-3.3	-2.2	3.3
Condit. Reinf. inactive responses	1.1	1.4	3.0	-1.1	0.0	1.7
Condit. Reinf. lever presses	1.1	1.5	3.5	-1.0	-0.4	1.9
Condit. Reinf. lever reinforcers received	5.4	7.6	9.9	-3.0	-2.0	3.1
Pavlov. Cond. lever latency	0.5	0.7	1.1	1.1	0.7	-0.6
Pavlov. Cond. magazine entry latency	1.0	1.1	2.8	0.3	-0.7	-1.7
Pavlov. Cond. change in total contacts	0.6	0.8	1.6	-1.3	-0.7	0.5
Pavlov. Cond. index score	0.3	0.4	0.8	-0.7	-0.9	-0.1
Pavlov. Cond. latency score	0.4	0.5	1.0	-0.6	-1.0	-0.1
Pavlov. Cond. lever contacts	0.3	0.4	0.5	-0.7	-0.4	0.7
Pavlov. Cond. magazine entry number	1.1	1.4	3.4	-0.5	0.7	1.8
Pavlov. Cond. intertrial magazine entries	5.9	7.6	18.3	-2.1	0.3	4.3
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	0.9	-0.7	-1.0	-0.2
Pavlov. Cond. response bias	0.3	0.4	0.5	-0.7	-0.7	0.2
Conditioned reinforcement - actives	0.5	0.5	1.2	-0.5	0.0	1.1
Conditioned reinforcement - inactives	0.6	0.7	1.6	-0.7	-0.0	1.3
Conditioned locomotion	1.7	2.1	4.6	-1.2	-0.4	2.2
Intermittent access intake day 1-15 change	0.3	0.3	0.8	0.4	0.9	0.3
Intermittent access intake escalation	0.5	0.5	1.0	0.7	1.0	0.1
Intermittent access intake escalation 2	0.5	0.5	0.8	0.3	0.9	0.7
Intermitt. access day 1 inactive lever presses	3.8	4.1	5.6	-2.4	-1.5	2.1
Intermitt. access day 15 inactive lever presses	1.1	1.2	2.9	0.2	0.8	1.7
Intermitt. access escalation Index	2.2	2.0	4.4	-0.2	-1.2	-2.1
Intermittent access day 1 total infusions	1.0	1.1	1.3	-1.1	-0.8	1.1
Intermittent access day 15 total infusions	0.3	0.3	0.9	-0.2	0.4	0.9
Intermittent access terminal intake (last 3 days)	1.3	1.5	3.3	-1.0	0.0	1.8
Intermittent access total infusions	2.0	2.2	4.5	-1.4	-0.5	2.1
Intermittent access day 1 locomotion	3.0	3.1	6.1	-1.7	-0.6	2.5
Intermittent access day 15 total locomotion	3.7	3.9	8.0	-1.9	-0.3	2.8
Intermittent access total locomotion	5.1	5.8	13.4	-2.0	-0.3	3.7
Intermittent access standard deviation	1.1	1.2	2.8	0.3	0.9	1.7
Cocaine induced anxiety	0.1	0.1	0.3	0.6	-0.2	-0.1
Post-drug Anxiety	0.2	0.2	0.5	0.7	-0.2	-0.1
Baseline Anxiety	0.3	0.3	0.5	0.7	0.1	-0.7
Lifetime Intake	2.2	2.4	5.0	-1.4	-0.5	2.2
Incentive Sensitization - Responses	3.1	3.1	4.7	-1.9	-0.9	2.2
Incentive Sensitization - Breakpoint	3.1	3.1	4.4	-2.0	-1.0	2.1
Progressive ratio test 1 active lever presses	4.2	4.3	5.6	-2.4	-1.4	2.4
Progressive ratio test 1 breakpoint	4.3	4.4	6.8	-2.3	-1.1	2.6
Progressive ratio test 1 inactive lever presses	3.7	3.9	5.7	-2.4	-1.1	2.2
Progressive ratio test 2 active lever presses	4.2	4.4	8.2	-2.1	-0.9	2.9
Progressive ratio test 2 breakpoint	4.5	5.0	9.6	-2.1	-1.0	3.1
Progressive ratio test 2 inactive lever presses	3.3	3.8	7.8	-1.9	-0.4	2.8
Total sessions with >9 infusions	0.5	0.5	0.8	-0.9	-0.6	0.7
Short access day 1 total inactive lever presses	1.0	1.1	1.7	-0.9	-0.8	1.3
Short access day 10 total inactive lever presses	0.3	0.3	0.5	-0.0	0.7	0.7
Short access day 1 total infusions	0.9	1.0	1.4	-1.2	-0.4	1.2
Short access day 10 total infusions	2.9	3.2	7.8	-1.3	-0.2	2.8
Short access total infusions	1.9	2.1	4.2	-1.4	-0.4	2.1
Short access day 1 locomotion	1.8	2.0	5.0	-0.9	0.0	2.2
Short access day 10 total locomotion	5.9	6.5	16.5	-1.7	0.4	4.1
Short access total locomotion	2.9	2.9	7.2	-1.1	0.5	2.7
Compulsive drug intake	0.9	0.9	1.4	0.1	-1.2	-1.1
One hour access (0.3 mA shock)	0.5	0.6	1.0	-0.9	-0.3	1.0
One hour access (shock baseline)	0.7	0.8	1.7	-0.6	0.6	1.3
Number of responses in last shaping day	0.5	0.5	0.9	-0.5	-0.6	1.0
Context. condit. distance diff. score	0.2	0.3	0.5	0.3	0.6	-0.7
Locomotion velocity, session 1	1.4	1.5	2.7	-0.8	-1.0	1.7
Locomotion distance, session 1	0.7	0.9	1.3	-0.6	-1.0	1.1
Locomotion velocity, session 2	0.4	0.5	0.6	-0.7	-0.8	0.6
Locomotion distance, session 2	0.5	0.7	1.2	-0.8	-1.1	0.5
Locomotion velocity, session 3	0.2	0.2	0.5	0.1	-0.7	-0.4
Locomotion distance, session 3	0.8	0.9	1.8	-0.8	-1.3	0.2
Stereotopy head waving bouts, day 3	0.1	0.2	0.4	0.7	-0.0	-0.1
Stereotopy head waving duration, day 3	0.0	0.1	0.1	0.2	-0.2	-0.3
Locomotion velocity, session 7	0.4	0.5	0.9	1.0	0.7	-0.2
Locomotion distance, session 7	0.0	0.0	0.1	-0.2	0.1	0.0
Stereotopy head waving bouts, day 7	0.2	0.2	0.2	0.4	-0.3	-0.5
Stereotopy head waving duration, day 7	0.9	1.1	2.7	0.6	-0.5	-1.6
Locomotion velocity, session 8	0.3	0.3	0.8	-0.9	-0.4	0.3
Locomotion distance, session 8	0.0	0.1	0.2	-0.4	-0.1	-0.2
Degree of sensitization distance	0.2	0.2	0.3	-0.3	0.6	0.4
Degree of sensitization stereotypy	0.5	0.5	1.3	0.6	-0.2	-1.1
Condit. Reinf. active minus inactive responses	1.5	1.7	2.9	-1.4	-0.4	1.7
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.7	-0.9	-0.1	0.7
Condit. Reinf. active responses	2.0	2.5	4.0	-1.8	-0.5	2.0
Condit. Reinf. inactive responses	1.6	1.9	2.4	-1.5	-1.0	1.5
Incentive salience index mean	1.7	2.0	3.8	-1.3	-0.7	2.0
Condit. Reinf. lever presses	0.2	0.2	0.6	-0.2	-0.1	0.8
Time in familiar zone, hab. session 1	0.3	0.3	0.5	-0.7	0.3	0.6
Time in novel zone, hab. session 1	1.0	0.9	1.6	1.3	0.3	-1.0
Total zone transitions, hab. session 1	0.2	0.3	0.9	-0.2	-0.3	1.0
Total locomotion distance, hab. session 1	1.1	1.6	4.4	-0.3	-0.7	2.1
Locomotion velocity, hab. session 1	1.6	2.3	5.4	-0.8	-1.0	2.3
Time in familiar zone, hab. session 2	0.6	0.6	1.0	-1.0	0.1	0.9
Time in novel zone, hab. session 2	0.5	0.5	0.7	0.8	-0.3	-0.8
Total zone transitions, hab. session 2	0.0	0.0	0.1	0.0	0.1	0.3
Total locomotion distance, hab. session 2	0.5	0.6	1.7	-0.0	0.4	1.3
Locomotion velocity, hab. session 2	0.5	0.6	1.9	-0.2	0.1	1.4
Novel to familiar place preference ratio	0.1	0.1	0.2	-0.2	-0.0	0.5
Novelty place preference	0.0	0.0	0.1	0.0	0.0	0.3
Time in novel zone, NPP test	0.0	0.0	0.0	0.0	-0.1	0.2
Total zone transitions, NPP test	0.4	0.6	0.9	-0.6	-1.0	0.7
Total locomotion distance, NPP test	0.9	1.2	2.9	-0.6	-0.7	1.7
Locomotion velocity, NPP test	0.6	0.8	2.3	-0.4	-0.2	1.5
Pavlov. Cond. lever latency	1.6	2.1	3.8	1.1	1.0	-2.0
Pavlov. Cond. magazine entry latency	2.0	2.6	4.5	-1.5	-0.9	2.1
Pavlov. Cond. change in total contacts	1.2	1.3	3.4	-0.7	-0.2	1.8
Pavlov. Cond. index score	2.0	2.5	4.2	-1.5	-1.0	2.1
Pavlov. Cond. latency score	1.7	2.1	3.4	-1.4	-1.0	1.8
Pavlov. Cond. lever contacts	0.9	1.0	2.7	-0.6	-0.3	1.6
Pavlov. Cond. magazine entry number	1.4	1.7	3.0	1.2	0.7	-1.7
Pavlov. Cond. intertrial magazine entries	0.9	1.1	2.1	-1.5	-0.1	1.1
Pavlov. Cond. lever-magazine prob. diff.	1.9	2.3	4.0	-1.4	-1.0	2.0
Pavlov. Cond. response bias	2.2	2.7	5.3	-1.3	-1.1	2.3
Bone: apparent density	1.8	2.9	3.7	-1.5	-1.9	1.7
Bone surface	7.7	13.6	14.0	-3.7	-3.7	3.6
Bone volume	5.6	9.5	10.0	-3.2	-3.1	3.0
Bone: connectivity density	3.0	4.7	5.1	-2.1	-2.3	2.1
Bone: cortical apparent density	3.1	4.0	5.7	2.4	1.4	-2.0
Bone: cortical area	1.4	2.1	3.4	-1.0	-1.4	1.8
Bone: cortical porosity	4.6	5.0	8.9	-1.9	-1.6	3.0
Bone: cortical porosity	4.0	4.3	5.9	-1.9	-1.9	2.4
Bone: cortical thickness	2.1	3.4	7.5	2.7	0.4	-1.6
Bone: cortical thickness	2.4	2.8	5.2	2.3	0.6	-1.7
Bone: cortical tissue density	3.2	4.2	6.0	2.4	1.6	-2.0
Bone: elastic displacement	0.5	0.6	0.9	0.9	-0.4	-0.9
Bone: elastic work	0.3	0.4	0.9	0.7	-0.1	0.9
Bone: endosteal estimation	10.5	22.7	32.5	-5.2	-2.9	5.7
Bone: endosteal perimeter	13.0	26.7	34.9	-5.9	-3.6	5.7
Bone: final force	2.2	3.7	5.7	-1.6	-2.4	1.7
Bone: final moment	2.2	3.7	5.5	-1.5	-2.3	1.8
Bone: marrow area	10.3	22.2	31.8	-5.1	-2.9	5.6
Bone: maximum diameter	5.7	10.4	12.0	-3.5	-3.1	3.1
Bone: maximum force	2.9	5.0	5.6	-2.0	-2.3	2.4
Bone: maximum moment	2.8	4.8	6.2	-1.9	-2.2	2.5
Bone: minimum diameter	9.0	16.6	25.9	-4.2	-2.5	5.1
Bone: periosteal estimation	7.7	15.8	23.1	-4.0	-2.9	4.8
Bone: periosteal perimeter	6.3	10.4	11.2	-3.3	-3.2	3.1
Bone: post-yield work	2.0	2.7	3.8	-1.7	-1.3	1.9
Bone: stiffness	2.5	4.0	5.4	-2.3	-2.3	1.2
Bone: tissue strength	0.7	0.7	1.6	-0.4	-1.3	-0.6
Bone: trabecular number	3.7	5.7	6.8	-2.4	-2.6	2.1
Bone: trabecular spacing	1.6	2.0	2.9	1.1	1.7	-1.4
Bone: trabecular thickness	2.3	2.8	4.8	-1.2	-1.4	2.2
Bone: trabecular tissue density	0.4	0.5	1.3	0.1	-1.2	-0.5
Breakpoint value in progressive ratio session	0.3	0.3	0.7	-0.8	-0.1	0.5
Distance traveled before self-admin	1.7	1.9	4.1	-0.7	-2.0	-1.0
Distance traveled after self-admin	1.3	1.4	2.5	-1.1	-1.6	-0.7
Delta time in closed arm before/after self-admin	0.8	0.8	2.0	-0.6	-1.4	0.4
Delta time in open arm before/after self-admin	1.7	1.6	3.2	1.1	1.8	-0.7
Diff in mean of infusions in LGA sessions	1.8	2.0	2.5	1.6	1.3	-1.3
Extinction: sum of active levers before priming	0.2	0.2	0.4	-0.4	0.6	0.4
Active lever presses in extinction session 6	0.7	0.7	1.7	-0.4	0.3	1.3
Delta distance traveled before/after self-admin	0.3	0.3	0.4	0.4	0.6	-0.6
Delta ambulatory time before/after self-admin	0.0	0.1	0.1	-0.3	0.2	0.2
Time in closed arm before self-admin	0.7	0.8	1.3	1.1	0.3	-1.1
Time in closed arm after self-admin	0.6	0.6	1.1	0.0	-1.0	-0.8
Time in open arm before self-admin	0.4	0.5	0.8	0.1	-0.8	-0.9
Time in open arm after self-admin	0.4	0.4	1.0	0.4	1.0	-0.1
Sum of active levers in priming session hrs 5-6	0.5	0.5	1.0	0.2	0.7	-1.0
Time to tail flick, vehicle, before self-admin	1.7	1.7	4.1	-1.0	-2.0	-0.2
Time to tail flick, vehicle, after self-admin	1.2	1.2	1.9	-1.4	-1.1	0.9
Time to tail flick, test, before self-admin	0.9	0.9	1.3	1.2	0.9	-0.7
Time to tail flick, test, after self-admin	0.1	0.1	0.1	-0.0	-0.4	-0.3
Delta time to tail flick, vehicle, before/after SA	1.1	1.1	2.5	-0.3	0.8	1.6
Delta time to tail flick, test, before/after SA	0.7	0.7	1.0	-1.0	-1.0	-0.1
Ambulatory time before self-admin	1.4	1.5	3.3	-0.8	-1.8	-0.6
Ambulatory time after self-admin	0.9	1.0	1.9	-1.1	-1.4	0.0
Total heroin consumption	1.3	1.6	2.6	-1.4	-1.6	0.3
Area under the delay curve	0.9	0.9	1.6	-1.3	-0.9	0.6
Delay disc. indifference point, 0s delay	0.3	0.3	0.5	-0.3	-0.5	-0.7
Delay disc. indifference point, 16s delay	0.9	0.9	1.7	-1.3	-0.7	0.7
Delay disc. indifference point, 2s delay	3.4	3.8	6.4	-2.5	-2.1	0.8
Delay disc. indifference point, 24s delay	2.1	2.0	3.6	-1.4	-0.7	1.9
Delay disc. indifference point, 4s delay	0.3	0.3	0.7	-0.4	-0.8	-0.5
Delay disc. indifference point, 8s delay	0.2	0.2	0.5	-0.4	-0.7	0.1
Delay discount exponential model param	1.2	1.3	2.2	1.5	1.0	-0.8
Delay discount hyperbolic model param	1.2	1.2	2.2	1.5	1.0	-0.6
Fecal boli incidents, locomotor time 1	0.1	0.1	0.1	-0.4	-0.2	-0.2
Change in fecal boli incidents, locomotor task	0.7	0.6	1.0	1.0	1.0	-0.0
Time >=10cm from walls, locomotor time 1	2.3	2.3	5.6	-0.2	-1.1	-2.4
Bouts of movement, locomotor time 1	1.7	1.9	3.0	1.5	1.7	-0.8
Total resting periods, locomotor time 1	1.6	1.8	2.7	1.5	1.6	-0.7
Rest time, locomotor task time 1	0.2	0.2	0.5	0.7	0.5	-0.2
Distance moved, locomotor task time 1	0.4	0.5	1.0	-0.7	-0.2	1.0
Vertical activity count, locomotor time 1	0.9	0.9	1.2	-1.0	-1.1	0.8
Time >=10cm from walls, locomotor time 2	0.3	0.3	0.6	0.6	-0.3	-0.7
Bouts of movement, locomotor time 2	1.9	2.0	3.5	1.2	1.9	-1.1
Total resting periods, locomotor time 2	2.0	2.2	3.0	1.3	1.7	-1.4
Rest time, locomotor task time 2	2.2	2.5	6.3	1.1	0.2	-2.5
Distance moved, locomotor task time 2	0.5	0.6	1.5	0.2	0.5	1.2
Vertical activity count, locomotor time 2	1.7	1.8	5.0	-0.2	0.6	2.2
Weight adjusted by age	0.4	0.4	1.2	0.0	-0.4	-1.1
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	2.0	0.6	1.4	0.4
Locomotion in novel chamber	1.4	1.7	3.4	-1.3	-1.8	0.3
Locomotion in novel chamber post-restriction	3.9	4.7	7.8	-2.8	-2.2	1.2
Progressive ratio	1.0	1.1	1.8	-1.3	-1.3	-0.0
Food seeking constrained by brief footshock	1.9	2.3	5.8	-1.1	-0.1	2.4
Seeking ratio, punishment vs. effort	0.7	0.9	1.9	0.3	0.8	1.4
Run reversals in cocaine runway, females	2.6	2.6	4.2	2.0	1.9	-0.3
Run reversals in cocaine runway, males	0.3	0.3	0.5	0.4	-0.7	-0.5
Latency to leave start box in cocaine runway	0.3	0.3	0.6	0.5	0.1	-0.8
Latency to leave start box in cocaine runway, F	0.5	0.5	1.1	0.3	-0.6	-1.0
Latency to leave start box in cocaine runway, M	0.5	0.5	1.2	0.5	1.1	-0.1
Cd content in liver	2.3	2.5	4.1	1.4	1.1	-2.0
Co content in liver	1.1	1.3	1.6	1.0	1.3	-1.2
Cu content in liver	0.2	0.3	0.5	0.3	0.7	0.5
Fe content in liver	0.1	0.1	0.2	-0.0	0.0	-0.4
K content in liver	3.1	3.1	5.4	-2.3	-2.0	0.3
Mg content in liver	0.3	0.3	0.5	-0.7	-0.3	-0.6
Mn content in liver	2.6	2.9	5.4	-1.8	-2.3	0.1
Na content in liver	1.4	1.5	3.0	-1.7	-1.2	-0.3
Rb content in liver	1.4	1.8	5.0	0.3	-0.6	-2.2
Se content in liver	0.8	1.0	2.7	-0.2	-0.6	-1.6
Sr content in liver	0.7	0.6	0.9	-0.5	-0.9	0.9
Zn content in liver	2.7	3.0	5.8	-1.8	-2.4	0.1