Hub : Genes

Map3k3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability ENSRNOG00000061424 0.04 0.02 3.6e-03 0.03 0.03 0.02 0.03 1.1e-03 6.1e-04 2.3e-03 1.1e-03
2 IL alternative TSS ENSRNOT00000088656 0.41 0.15 3.7e-03 0 0.06 0.06 0.06 3.1e-01 1.3e-02 1.6e-02 1.9e-02
3 IL alternative TSS ENSRNOT00000095570 0.43 0.15 2.6e-03 0 0.07 0.07 0.06 2.6e-01 8.0e-03 7.7e-03 1.3e-02
4 IL isoform ratio ENSRNOT00000088656 0.4 0.16 8.8e-03 0.04 0.03 0.01 0.02 3.2e-02 7.5e-02 2.3e-01 1.0e-01
5 IL isoform ratio ENSRNOT00000095570 0.44 0.16 4.0e-03 0.05 0.05 0.02 0.04 2.2e-02 3.0e-02 1.2e-01 4.6e-02
6 Liver gene expression ENSRNOG00000061424 0.03 0.02 1.6e-03 0 0.01 0.01 0 1.1e-01 1.1e-02 3.3e-02 9.4e-02
7 Liver mRNA stability ENSRNOG00000061424 0.03 0.02 9.5e-04 0.01 0.01 0 0.01 1.0e-02 7.0e-03 7.9e-02 2.3e-02
8 NAcc alternative TSS ENSRNOT00000088656 0.1 0.06 9.2e-03 0 0.02 0.02 0.01 2.2e-01 9.0e-03 7.6e-03 3.5e-02
9 NAcc alternative TSS ENSRNOT00000095570 0.1 0.06 9.8e-03 0 0.02 0.02 0.01 2.3e-01 1.3e-02 1.4e-02 6.0e-02
10 NAcc mRNA stability ENSRNOG00000061424 0.06 0.04 9.9e-04 0.02 0.03 0.04 0.04 1.3e-02 3.3e-03 5.6e-04 4.0e-04
11 PL gene expression ENSRNOG00000061424 0.03 0.02 9.4e-03 0.01 0 -0 -0 3.0e-02 2.6e-01 4.2e-01 4.0e-01
12 PL mRNA stability ENSRNOG00000061424 0.05 0.03 2.2e-04 0.01 0.04 0.02 0.01 2.5e-02 9.7e-04 9.0e-03 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.82.68.61.40.3-0.2-1.11.12.3-0.72.9-2.40.2-0.5-2.6
BMI without tail1.22.510.9-0.50.9-0.7-1.41.40.8-1.91.3-1.1-1.4-2.2-3.3
Body weight1.77.219.5-1.33.1-3.2-0.10.1-0.9-3.72.7-2.8-2.8-3.0-4.4
Epididymis fat weight0.71.66.1-1.00.7-0.4-1.21.20.1-1.61.1-0.8-1.5-1.5-2.5
Glucose0.61.02.51.60.2-0.30.7-0.71.10.71.5-1.41.01.00.5
Heart weight0.71.02.80.51.4-1.20.8-0.80.6-0.61.6-1.7-0.1-0.0-1.0
Left kidney weight0.51.53.40.21.4-0.91.8-1.80.10.21.6-1.70.41.50.4
Right kidney weight0.51.43.9-0.51.6-1.02.0-2.0-0.9-0.21.1-1.3-0.11.00.4
Tail length1.33.87.8-2.51.8-1.9-0.40.4-2.1-2.7-0.50.0-2.7-2.8-2.4
Length with tail1.86.411.7-2.63.3-3.41.3-1.3-3.1-3.30.6-1.2-3.1-2.6-2.3
Length without tail0.81.73.7-1.21.8-1.81.6-1.6-1.9-1.20.6-0.9-1.2-0.4-0.3
Liver weight, left1.21.93.2-1.41.5-1.71.5-1.5-1.8-0.9-1.51.0-1.5-1.1-0.1
Liver weight, right1.11.86.4-1.21.8-0.92.5-2.5-0.90.20.2-0.1-0.31.10.8
Parametrial fat weight1.22.37.0-2.71.7-1.10.8-0.8-2.3-1.7-0.1-0.4-2.1-1.3-1.1
Retroperitoneal fat weight0.72.25.1-1.80.6-0.8-1.21.2-1.2-2.1-0.10.1-1.9-2.0-2.3
Intraocular pressure1.11.65.7-0.20.6-0.4-1.31.30.8-1.31.7-1.5-0.8-1.2-2.4
Extensor digitorum longus weight2.28.734.44.4-3.13.0-2.62.65.92.50.60.23.30.6-0.9
Soleus weight0.41.23.7-0.11.3-1.30.4-0.4-0.6-1.21.8-1.9-0.8-0.6-1.1
Tibialis anterior weight0.62.25.31.4-1.40.9-2.22.22.3-0.20.2-0.10.3-1.4-2.2
Tibia length0.92.66.1-1.32.5-1.92.4-2.4-1.6-0.81.5-1.4-0.80.50.1
Number of licking bursts0.30.40.90.20.9-0.90.9-0.9-0.4-0.30.7-0.8-0.20.10.0
Food consumed during 24 hour testing period1.61.96.5-0.70.6-1.0-1.21.2-0.2-1.90.3-0.2-1.5-2.3-2.5
Times rat made contact with spout0.40.51.3-0.70.6-0.7-0.20.2-0.9-1.10.5-0.6-0.8-0.9-0.9
Mean time between licks in bursts0.81.12.80.41.4-1.30.7-0.70.4-0.81.7-1.6-0.4-0.3-1.2
Mean num. licks in bursts0.40.51.4-0.5-0.60.6-1.21.20.2-0.4-0.30.4-0.4-0.6-0.8
Std. dev. time between licks in bursts0.20.20.60.3-0.50.5-0.80.80.70.1-0.10.20.2-0.2-0.4
Water consumed over 24 hours0.10.10.4-0.70.20.1-0.10.1-0.4-0.30.3-0.1-0.3-0.2-0.3
Indifference point 0 sec2.23.57.3-2.61.3-1.5-0.60.6-1.7-2.3-1.41.3-2.7-2.7-2.1
Indifference point AUC0.50.51.6-0.30.5-0.8-0.10.1-0.1-0.9-0.40.4-1.0-1.3-1.2
Indifference point function ln k0.20.30.8-0.90.50.10.6-0.6-0.80.2-0.1-0.1-0.10.40.7
Indifference point function log k0.20.30.8-0.90.50.10.6-0.6-0.80.2-0.1-0.1-0.10.40.7
Delay discounting total patch changes 0 sec2.43.98.2-2.71.6-1.8-0.50.5-1.9-2.5-1.00.9-2.9-2.8-2.3
Delay discounting total patch changes 12 sec2.33.07.2-1.70.8-1.5-0.60.6-1.1-1.8-2.22.2-2.4-2.7-1.8
Delay discounting total patch changes 18 sec1.21.63.7-0.90.6-1.2-1.01.0-0.7-1.80.3-0.2-1.6-1.9-1.9
Delay discounting total patch changes 24 sec2.43.16.9-2.51.7-1.80.2-0.2-2.0-2.1-0.90.7-2.6-2.2-1.7
Delay discounting total patch changes 6 sec1.32.04.4-1.71.2-1.4-0.20.2-1.5-1.9-0.20.1-2.1-2.0-1.6
Delay discounting time to switch 0 sec0.30.51.40.6-1.21.1-0.90.90.30.6-0.0-0.10.80.40.7
Delay discounting water rate 0 sec0.91.53.6-1.71.0-0.9-0.50.5-1.0-1.80.4-0.4-1.7-1.4-1.9
Delay discounting water rate 12 sec1.01.54.9-0.01.1-0.41.4-1.4-0.20.22.2-2.10.41.50.6
Delay discounting water rate 18 sec0.91.12.7-1.41.3-0.81.7-1.7-1.6-0.30.2-0.2-0.70.60.7
Delay discounting water rate 24 sec0.40.61.6-0.31.2-1.01.3-1.3-0.6-0.30.7-0.7-0.10.40.2
Delay discounting water rate 6 sec0.50.72.3-1.51.1-0.40.9-0.9-1.2-0.40.6-0.8-0.70.20.1
Locomotor activity0.10.20.7-0.2-0.1-0.4-0.40.4-0.5-0.6-0.50.5-0.3-0.8-0.4
Locomotor testing distance0.71.12.9-0.5-0.5-0.2-1.71.7-0.5-1.2-0.40.4-0.8-1.6-1.3
Locomotor testing rearing1.52.39.20.5-2.01.0-3.03.00.2-0.7-0.50.50.1-1.4-1.0
Light reinforcement 10.71.35.8-1.3-0.10.5-0.30.30.00.0-2.42.3-0.9-1.2-0.4
Light reinforcement 21.01.34.3-2.10.30.10.1-0.1-0.9-0.4-1.91.9-1.4-0.9-0.3
Reaction time number correct1.11.54.90.01.8-1.22.2-2.20.00.21.2-1.00.11.10.4
Reaction time mean minus median0.40.51.20.5-1.01.1-0.90.90.70.7-0.0-0.00.90.60.4
Reaction time mean minus median AUC0.60.71.70.6-0.40.70.5-0.50.71.3-0.60.51.21.21.3
Reaction time num false alarms2.43.36.5-1.42.2-2.50.5-0.5-1.9-2.50.6-1.3-2.3-2.2-1.9
Reaction time num false alarms AUC2.63.76.7-1.92.3-2.60.6-0.6-2.3-2.60.2-0.9-2.5-2.4-1.9
Reaction time trials correct on left1.11.54.90.01.8-1.22.2-2.20.00.21.2-1.00.11.10.4
Reaction time trials on left1.11.54.9-0.01.9-1.32.2-2.2-0.00.11.2-1.00.11.10.4
Reaction time mean0.91.23.20.3-1.31.4-0.30.30.21.4-1.01.01.21.21.8
Reaction time mean AUC1.41.84.00.6-1.81.8-0.60.60.51.7-1.21.31.61.32.0
Median of all reaction times0.91.33.80.2-1.31.4-0.20.20.11.5-1.11.21.21.21.9
Reaction time omissions0.20.21.6-1.30.10.4-0.30.3-0.7-0.10.0-0.0-0.30.30.3
Reaction time false alarm rate1.72.45.9-1.40.9-1.5-0.80.8-1.9-2.3-0.2-0.5-2.1-2.4-1.8
Reaction time premature initiation rate0.50.71.8-1.00.2-0.1-0.80.8-0.4-1.00.0-0.1-1.1-1.3-1.4
Reaction time premature initiations0.40.61.4-0.91.2-0.90.5-0.5-0.3-0.90.4-0.4-1.0-0.7-1.1
Std. dev. reaction times0.50.71.80.2-1.21.3-0.60.60.41.0-0.70.71.00.81.0
Reaction time trials completed1.11.54.9-0.01.9-1.32.2-2.2-0.00.11.2-1.00.11.10.4
Reaction time trials AUC1.01.44.60.01.8-1.22.2-2.20.10.21.1-0.90.11.10.4
Social response proportion0.80.93.51.10.6-0.60.2-0.20.9-0.11.9-1.80.50.5-0.7
Social responses0.10.10.30.40.3-0.4-0.20.20.2-0.40.4-0.6-0.1-0.4-0.6
Social time1.01.35.90.50.7-0.8-0.40.40.1-0.92.4-2.4-0.50.0-1.1
Conditioned locomotion0.50.61.8-0.3-0.50.2-1.01.00.3-0.2-1.31.4-0.5-0.9-0.6
Cocaine response after cond. corrected1.71.96.00.21.7-1.41.7-1.7-0.3-0.42.5-2.20.00.7-0.1
Cocaine response after cond. not corrected2.22.46.3-0.01.6-1.42.1-2.1-1.2-0.32.5-2.50.11.10.7
Cocaine response before conditioning0.30.41.6-0.5-0.10.20.6-0.6-1.30.3-0.50.10.00.51.3
Saline control response1.31.75.10.1-1.30.6-2.32.30.6-0.6-1.11.1-0.5-1.7-1.4
Condit. Reinf. active minus inactive responses5.26.415.2-3.32.9-3.01.4-1.4-3.9-3.1-0.3-0.4-3.5-2.3-1.4
Condit. Reinf. active-inactive response ratio3.23.410.4-2.61.8-1.80.7-0.7-3.2-2.3-0.0-0.6-2.5-1.7-0.9
Condit. Reinf. active responses3.85.312.0-3.12.1-2.40.3-0.3-3.2-3.0-0.80.2-3.5-2.7-1.9
Condit. Reinf. inactive responses1.01.22.6-1.20.1-0.4-0.90.9-0.4-1.0-1.51.4-1.4-1.6-1.1
Condit. Reinf. lever presses0.81.12.6-1.40.4-0.6-0.60.6-1.6-1.5-0.2-0.1-1.5-1.4-0.9
Condit. Reinf. lever reinforcers received3.44.811.0-3.02.1-2.30.3-0.3-3.1-2.9-0.60.1-3.3-2.5-1.8
Pavlov. Cond. lever latency0.30.40.90.6-0.80.9-0.70.70.90.70.20.10.80.50.2
Pavlov. Cond. magazine entry latency1.51.73.61.90.0-0.11.6-1.61.01.50.6-0.61.71.81.6
Pavlov. Cond. change in total contacts0.20.31.10.00.3-0.90.5-0.5-0.4-0.3-1.10.8-0.5-0.8-0.1
Pavlov. Cond. index score0.30.30.90.40.6-0.81.0-1.0-0.4-0.10.4-0.70.00.30.4
Pavlov. Cond. latency score0.40.41.10.50.6-0.81.1-1.1-0.4-0.10.6-0.90.10.40.5
Pavlov. Cond. lever contacts0.20.20.5-0.60.4-0.50.2-0.2-0.7-0.5-0.40.3-0.7-0.5-0.1
Pavlov. Cond. magazine entry number1.82.24.8-1.90.1-0.2-1.71.7-1.0-1.7-0.60.5-1.9-2.2-2.0
Pavlov. Cond. intertrial magazine entries7.19.222.0-3.61.6-1.8-2.12.1-2.4-4.2-0.3-0.1-4.3-4.7-4.4
Pavlov. Cond. lever-magazine prob. diff.0.30.41.40.50.7-0.91.2-1.2-0.30.00.4-0.60.10.40.5
Pavlov. Cond. response bias0.20.20.7-0.10.6-0.60.8-0.8-0.4-0.1-0.20.1-0.20.10.3
Conditioned reinforcement - actives0.40.41.5-0.20.4-0.7-0.40.4-0.0-0.90.3-0.3-0.8-0.9-1.2
Conditioned reinforcement - inactives0.80.91.9-0.90.8-0.9-0.40.4-0.8-1.40.7-0.8-1.2-1.0-1.4
Conditioned locomotion1.72.04.3-1.51.1-1.3-0.60.6-1.3-2.10.5-0.9-2.0-1.7-2.0
Intermittent access intake day 1-15 change0.70.71.70.8-0.60.1-1.31.30.4-0.51.3-1.00.2-0.4-0.8
Intermittent access intake escalation0.50.51.40.8-0.80.5-1.21.20.5-0.10.8-0.60.5-0.0-0.3
Intermittent access intake escalation 20.50.51.60.2-0.50.1-1.21.2-0.1-0.70.7-0.6-0.2-0.7-0.8
Intermitt. access day 1 inactive lever presses2.83.17.1-2.41.5-1.8-0.20.2-2.7-2.40.1-0.4-2.6-2.0-1.5
Intermitt. access day 15 inactive lever presses2.12.35.3-2.0-0.50.6-2.32.3-1.4-1.60.2-0.3-1.6-1.6-1.5
Intermitt. access escalation Index2.32.14.51.90.6-0.52.1-2.11.01.40.8-0.61.51.81.6
Intermittent access day 1 total infusions1.21.32.9-0.91.7-1.60.7-0.7-0.7-1.40.8-0.9-1.4-1.1-1.4
Intermittent access day 15 total infusions0.60.62.30.20.5-0.7-0.50.50.3-1.01.1-0.9-0.6-0.9-1.5
Intermittent access terminal intake (last 3 days)1.41.64.4-0.80.9-1.2-0.70.7-0.6-1.80.7-0.7-1.6-1.8-2.1
Intermittent access total infusions1.71.94.2-1.21.3-1.6-0.20.2-1.0-2.00.4-0.5-1.9-1.9-2.1
Intermittent access day 1 locomotion3.33.46.8-1.71.9-2.0-0.10.1-1.6-2.61.1-1.6-2.4-2.1-2.5
Intermittent access day 15 total locomotion2.82.96.7-1.51.2-1.7-0.70.7-1.5-2.60.4-0.8-2.3-2.4-2.6
Intermittent access total locomotion4.55.111.0-2.51.6-1.9-1.11.1-2.2-3.30.4-0.9-3.2-3.0-3.2
Intermittent access standard deviation1.11.22.9-0.9-0.40.2-1.71.7-0.7-1.30.5-0.4-1.0-1.3-1.4
Cocaine induced anxiety0.40.52.2-0.80.60.10.2-0.2-0.7-0.31.3-1.5-0.20.50.0
Post-drug Anxiety0.80.84.5-0.50.7-0.10.3-0.3-0.5-0.32.0-2.1-0.10.7-0.1
Baseline Anxiety0.30.41.00.6-0.00.30.5-0.50.60.70.4-0.40.81.00.6
Lifetime Intake1.92.24.6-1.61.2-1.4-0.40.4-1.3-2.10.0-0.2-2.1-2.1-2.0
Incentive Sensitization - Responses2.42.45.0-1.51.6-1.90.0-0.0-1.5-2.20.5-0.7-2.2-1.9-2.0
Incentive Sensitization - Breakpoint2.32.44.7-1.41.7-2.00.2-0.2-1.5-2.20.6-0.8-2.2-1.8-1.9
Progressive ratio test 1 active lever presses3.23.37.1-2.02.0-2.20.3-0.3-1.9-2.50.0-0.4-2.7-2.2-2.1
Progressive ratio test 1 breakpoint3.73.88.5-2.11.9-2.2-0.10.1-1.8-2.70.0-0.3-2.9-2.6-2.5
Progressive ratio test 1 inactive lever presses3.03.27.3-1.91.9-2.20.2-0.2-1.8-2.4-0.30.0-2.7-2.5-2.0
Progressive ratio test 2 active lever presses3.63.98.5-2.32.0-2.2-0.10.1-2.0-2.70.2-0.6-2.9-2.4-2.5
Progressive ratio test 2 breakpoint4.34.89.8-2.32.2-2.4-0.20.2-2.1-3.10.7-1.2-3.1-2.7-2.8
Progressive ratio test 2 inactive lever presses2.83.37.2-2.21.6-1.7-0.30.3-1.5-2.4-0.10.0-2.7-2.6-2.5
Total sessions with >9 infusions0.30.40.8-0.70.9-0.70.7-0.7-0.2-0.4-0.50.5-0.7-0.5-0.5
Short access day 1 total inactive lever presses1.01.12.1-1.11.1-1.10.2-0.2-1.4-1.41.1-1.4-1.2-0.7-1.0
Short access day 10 total inactive lever presses0.40.41.1-0.6-0.00.0-1.01.0-0.1-0.70.10.2-0.7-1.1-1.0
Short access day 1 total infusions0.70.71.8-0.80.9-0.90.1-0.1-0.4-1.0-0.60.5-1.2-1.3-1.1
Short access day 10 total infusions3.33.78.4-2.01.2-1.5-1.11.1-1.5-2.70.3-0.5-2.7-2.9-2.8
Short access total infusions1.71.94.9-1.50.8-1.1-0.80.8-1.3-1.9-0.30.0-2.0-2.2-1.8
Short access day 1 locomotion2.42.56.7-1.61.4-1.4-0.60.6-0.8-2.20.4-0.7-2.2-2.2-2.6
Short access day 10 total locomotion5.66.114.1-2.30.9-1.6-2.22.2-1.8-3.50.2-0.6-3.3-3.7-3.7
Short access total locomotion3.03.18.1-1.40.8-1.2-1.51.5-1.0-2.50.5-0.8-2.3-2.6-2.9
Compulsive drug intake1.21.22.80.40.9-0.51.7-1.7-0.30.51.2-1.40.71.41.1
One hour access (0.3 mA shock)0.70.81.7-0.30.8-1.2-0.20.2-0.5-1.30.7-0.8-1.1-1.2-1.3
One hour access (shock baseline)0.70.92.4-0.3-0.1-0.5-1.21.2-0.1-1.1-0.30.5-1.0-1.5-1.5
Number of responses in last shaping day1.61.64.5-0.81.1-1.0-0.40.4-1.0-1.62.0-2.1-1.3-0.8-1.5
Context. condit. distance diff. score0.40.52.41.5-0.70.3-0.20.21.40.6-0.30.20.8-0.1-0.1
Locomotion velocity, session 11.01.14.0-2.00.8-0.60.2-0.2-1.9-1.2-0.1-0.1-1.4-0.9-0.4
Locomotion distance, session 10.30.41.8-1.30.7-0.40.5-0.5-0.9-0.4-0.20.4-0.50.10.0
Locomotion velocity, session 20.40.42.0-0.8-0.50.1-0.60.6-1.4-0.4-0.70.7-0.4-0.10.6
Locomotion distance, session 20.20.31.0-0.40.0-0.20.5-0.5-0.60.2-0.81.00.10.40.7
Locomotion velocity, session 30.20.20.60.10.2-0.00.7-0.7-0.30.30.4-0.50.40.50.7
Locomotion distance, session 30.40.50.9-0.30.8-0.91.0-1.0-0.9-0.30.6-0.7-0.20.10.3
Stereotopy head waving bouts, day 30.20.30.6-0.7-0.20.70.4-0.4-0.40.5-0.50.50.10.70.8
Stereotopy head waving duration, day 30.20.30.70.00.10.10.8-0.80.20.6-0.60.60.20.40.5
Locomotion velocity, session 70.30.40.90.2-0.91.0-0.10.10.20.7-0.40.40.80.60.8
Locomotion distance, session 70.10.20.80.2-0.30.2-0.20.20.60.3-0.70.90.2-0.00.1
Stereotopy head waving bouts, day 70.30.41.6-0.3-0.30.50.6-0.6-0.50.7-0.50.50.40.81.2
Stereotopy head waving duration, day 71.31.65.60.5-0.90.91.0-1.0-0.11.7-1.21.21.31.52.4
Locomotion velocity, session 80.30.41.10.80.2-0.8-0.20.20.2-0.70.5-0.8-0.1-0.9-1.0
Locomotion distance, session 80.30.52.20.7-0.60.0-0.00.00.60.5-1.51.40.4-0.30.3
Degree of sensitization distance0.40.41.10.2-0.20.1-0.60.61.0-0.0-0.91.0-0.1-0.5-0.7
Degree of sensitization stereotypy0.70.82.80.6-0.90.80.2-0.20.01.1-0.30.41.21.31.7
Condit. Reinf. active minus inactive responses1.31.43.1-1.30.3-0.8-1.11.1-1.4-1.7-0.3-0.1-1.7-1.7-1.3
Condit. Reinf. active-inactive response ratio0.50.51.3-0.7-0.0-0.4-0.70.7-1.0-1.0-0.40.1-1.1-1.1-0.6
Condit. Reinf. active responses1.72.04.9-1.70.6-1.1-0.90.9-1.6-1.9-0.90.5-2.0-2.2-1.5
Condit. Reinf. inactive responses0.91.12.2-1.51.2-1.10.4-0.4-1.1-1.1-0.90.7-1.4-1.3-0.9
Incentive salience index mean1.31.64.5-1.80.4-0.8-0.70.7-2.1-1.7-0.60.1-1.8-1.6-0.9
Condit. Reinf. lever presses0.40.51.8-1.0-0.30.2-0.40.4-1.3-0.4-1.00.8-0.6-0.70.2
Time in familiar zone, hab. session 10.50.41.30.5-0.0-0.5-0.70.70.7-0.5-0.30.3-0.3-1.1-1.1
Time in novel zone, hab. session 10.60.51.9-0.1-0.41.00.3-0.3-0.20.80.7-0.70.71.41.1
Total zone transitions, hab. session 10.10.10.4-0.20.3-0.4-0.10.1-0.0-0.50.3-0.2-0.1-0.4-0.7
Total locomotion distance, hab. session 10.60.93.9-2.00.7-0.4-0.00.0-1.7-1.20.1-0.1-1.1-0.5-0.6
Locomotion velocity, hab. session 10.81.14.1-2.00.9-0.80.1-0.1-1.8-1.4-0.10.1-1.3-0.8-0.8
Time in familiar zone, hab. session 20.60.61.90.7-0.1-0.7-0.80.80.3-0.8-0.60.3-0.5-1.4-1.1
Time in novel zone, hab. session 20.70.72.2-1.10.40.60.9-0.9-0.70.60.7-0.40.31.51.2
Total zone transitions, hab. session 20.10.10.70.3-0.30.0-0.10.10.40.1-0.70.80.3-0.3-0.1
Total locomotion distance, hab. session 20.60.83.9-1.1-0.20.3-0.30.3-0.3-0.2-1.82.0-0.5-0.7-0.3
Locomotion velocity, hab. session 20.50.73.7-1.20.00.1-0.00.0-0.3-0.2-1.71.9-0.5-0.7-0.3
Novel to familiar place preference ratio0.50.61.3-0.60.9-0.80.2-0.2-0.6-0.91.0-1.2-0.8-0.5-0.8
Novelty place preference0.30.30.9-0.40.6-0.50.2-0.2-0.5-0.60.8-1.0-0.6-0.2-0.5
Time in novel zone, NPP test0.30.31.0-0.40.6-0.50.2-0.2-0.6-0.50.9-1.0-0.5-0.1-0.3
Total zone transitions, NPP test0.30.41.3-0.80.6-0.40.9-0.9-0.4-0.0-1.01.2-0.2-0.00.2
Total locomotion distance, NPP test0.60.83.8-1.90.4-0.20.1-0.1-1.4-0.6-1.11.3-0.9-0.4-0.1
Locomotion velocity, NPP test0.40.62.5-1.60.5-0.20.0-0.0-0.7-0.5-1.01.3-0.8-0.5-0.5
Pavlov. Cond. lever latency1.41.86.62.0-0.91.00.1-0.12.61.8-0.20.61.81.20.8
Pavlov. Cond. magazine entry latency2.12.77.4-2.41.1-1.2-0.30.3-2.7-2.2-0.50.0-2.3-2.0-1.2
Pavlov. Cond. change in total contacts1.61.74.8-1.90.1-0.3-0.90.9-2.2-1.7-0.50.1-1.7-1.7-1.0
Pavlov. Cond. index score1.82.37.0-2.21.1-1.2-0.10.1-2.7-2.1-0.2-0.2-2.2-1.8-1.1
Pavlov. Cond. latency score1.51.95.6-1.81.0-1.2-0.00.0-2.4-1.9-0.1-0.3-1.9-1.6-1.0
Pavlov. Cond. lever contacts1.01.13.6-1.30.3-0.5-0.70.7-1.9-1.60.3-0.7-1.3-1.2-0.9
Pavlov. Cond. magazine entry number1.72.16.72.4-0.70.80.1-0.12.61.71.0-0.52.11.70.7
Pavlov. Cond. intertrial magazine entries0.70.82.5-0.30.8-1.0-0.30.30.6-0.9-0.70.8-1.0-1.3-1.6
Pavlov. Cond. lever-magazine prob. diff.1.82.36.7-2.11.2-1.3-0.10.1-2.6-2.10.1-0.6-2.1-1.7-1.2
Pavlov. Cond. response bias2.43.010.9-2.91.1-1.0-0.10.1-3.3-2.2-0.3-0.2-2.4-1.6-0.9
Bone: apparent density2.23.613.3-3.61.8-1.01.2-1.2-3.6-1.7-0.50.1-2.4-1.0-0.2
Bone surface6.110.727.4-4.53.8-3.61.6-1.6-5.2-4.01.2-1.9-4.2-2.4-1.9
Bone volume5.18.622.1-4.43.4-2.91.5-1.5-4.7-3.50.7-1.4-3.9-2.2-1.7
Bone: connectivity density2.53.913.8-3.71.8-1.31.0-1.0-3.7-2.0-0.70.3-2.6-1.2-0.3
Bone: cortical apparent density2.93.88.50.7-1.72.50.6-0.61.72.9-2.12.52.12.02.4
Bone: cortical area2.84.27.0-2.62.6-2.01.1-1.1-2.6-2.41.8-2.1-2.5-1.3-1.6
Bone: cortical porosity8.08.719.6-2.32.1-2.5-0.80.8-3.9-4.13.7-4.4-3.1-2.2-2.7
Bone: cortical porosity6.87.318.9-1.92.4-2.70.1-0.1-3.2-3.53.8-4.3-2.6-1.5-2.3
Bone: cortical thickness1.11.95.5-0.40.11.41.5-1.50.01.51.4-1.11.22.31.7
Bone: cortical thickness1.41.65.0-0.0-1.01.90.3-0.3-0.01.60.7-0.31.42.22.1
Bone: cortical tissue density3.14.08.60.8-1.82.60.4-0.41.82.9-2.12.52.11.92.4
Bone: elastic displacement0.80.92.70.4-0.10.50.9-0.9-0.10.81.3-1.21.01.61.1
Bone: elastic work0.50.72.5-1.10.50.00.2-0.2-1.3-0.71.4-1.6-0.50.3-0.2
Bone: endosteal estimation7.816.938.0-4.13.5-4.7-1.11.1-4.9-6.21.1-2.1-5.7-5.2-4.8
Bone: endosteal perimeter10.922.447.3-3.95.0-6.10.1-0.1-5.0-6.92.4-3.4-6.3-5.5-5.6
Bone: final force2.23.57.0-2.32.6-2.01.9-1.9-2.6-1.81.4-1.6-2.0-0.6-0.6
Bone: final moment2.23.67.8-2.42.6-2.01.8-1.8-2.8-1.81.4-1.7-2.0-0.6-0.6
Bone: marrow area7.716.537.2-4.03.4-4.6-1.11.1-4.9-6.11.2-2.1-5.7-5.1-4.7
Bone: maximum diameter5.610.216.8-3.44.1-4.01.4-1.4-4.0-4.12.0-2.6-4.1-2.6-2.7
Bone: maximum force2.95.010.5-2.73.2-2.71.6-1.6-2.6-2.51.6-1.8-2.7-1.3-1.7
Bone: maximum moment2.95.09.7-2.83.1-2.51.5-1.5-2.7-2.61.6-1.9-2.7-1.3-1.7
Bone: minimum diameter9.217.035.5-4.04.3-4.7-0.10.1-4.4-6.02.1-3.0-5.5-4.9-5.0
Bone: periosteal estimation7.314.929.7-4.54.0-4.20.2-0.2-5.0-5.51.8-2.6-5.3-4.1-3.9
Bone: periosteal perimeter7.011.618.7-2.94.3-4.31.7-1.7-4.0-4.33.0-3.7-4.0-2.4-2.9
Bone: post-yield work2.33.26.0-0.92.1-2.40.2-0.2-1.5-2.42.0-2.3-1.9-1.5-2.1
Bone: stiffness1.42.36.0-1.22.5-2.31.8-1.8-1.4-1.3-0.0-0.2-1.6-1.0-0.7
Bone: tissue strength0.90.92.80.40.8-0.51.7-1.70.30.80.4-0.10.81.31.0
Bone: trabecular number3.04.614.4-3.72.3-1.81.5-1.5-3.8-2.1-0.50.1-2.8-1.3-0.4
Bone: trabecular spacing1.41.97.22.7-1.40.8-1.01.02.51.20.00.21.70.40.0
Bone: trabecular thickness3.74.512.9-3.62.3-1.50.7-0.7-3.3-2.51.1-1.4-2.8-1.4-1.4
Bone: trabecular tissue density0.91.34.4-0.81.4-0.42.1-2.1-0.10.70.30.10.21.50.9
Breakpoint value in progressive ratio session0.40.41.8-0.1-0.1-0.5-0.60.6-0.5-0.7-0.90.2-0.6-1.4-0.5
Distance traveled before self-admin2.52.69.90.91.9-1.71.7-1.7-0.3-0.62.7-3.10.10.6-0.1
Distance traveled after self-admin1.61.76.51.41.2-1.71.1-1.10.0-0.52.3-2.60.20.6-0.2
Delta time in closed arm before/after self-admin0.30.31.0-0.30.4-0.50.8-0.8-1.0-0.20.1-0.5-0.10.40.5
Delta time in open arm before/after self-admin1.01.02.80.8-1.01.0-0.60.61.71.0-1.31.70.6-0.20.0
Diff in mean of infusions in LGA sessions0.80.92.01.4-1.11.1-0.60.61.41.10.1-0.11.40.70.5
Extinction: sum of active levers before priming0.40.41.40.40.0-0.3-0.30.30.6-0.2-1.20.8-0.2-1.0-0.7
Active lever presses in extinction session 61.51.42.8-0.80.5-0.8-1.11.1-0.9-1.70.6-1.0-1.5-1.7-1.7
Delta distance traveled before/after self-admin0.40.51.30.7-1.10.8-0.50.50.50.7-0.50.60.60.60.6
Delta ambulatory time before/after self-admin0.20.31.2-0.1-0.70.4-0.30.3-0.10.3-1.01.10.00.10.4
Time in closed arm before self-admin0.70.92.10.5-1.21.4-0.30.30.21.1-0.30.21.11.31.4
Time in closed arm after self-admin0.70.72.60.8-0.60.50.6-0.6-0.20.9-0.2-0.11.11.51.6
Time in open arm before self-admin1.31.46.51.00.7-0.60.7-0.70.2-0.12.5-2.50.60.9-0.0
Time in open arm after self-admin0.60.72.40.50.5-0.5-0.40.41.1-0.61.2-0.9-0.3-0.8-1.5
Sum of active levers in priming session hrs 5-60.70.71.71.1-0.70.5-0.20.21.20.9-1.31.20.8-0.20.4
Time to tail flick, vehicle, before self-admin2.32.35.7-0.42.1-1.72.0-2.0-1.1-0.61.9-2.4-0.40.80.2
Time to tail flick, vehicle, after self-admin1.21.23.0-1.21.7-1.41.1-1.1-0.8-1.0-0.10.0-1.6-1.0-0.9
Time to tail flick, test, before self-admin0.80.81.61.3-1.00.9-0.60.61.00.80.7-0.51.31.00.4
Time to tail flick, test, after self-admin0.10.10.3-0.30.5-0.10.5-0.5-0.30.00.4-0.4-0.30.30.3
Delta time to tail flick, vehicle, before/after SA1.91.95.0-1.5-0.40.2-1.11.1-0.5-0.8-2.12.2-1.6-1.9-1.0
Delta time to tail flick, test, before/after SA0.60.61.3-0.70.9-0.61.1-1.1-0.6-0.0-0.90.8-0.7-0.30.3
Ambulatory time before self-admin2.32.48.80.81.9-1.91.5-1.5-0.4-0.72.6-3.0-0.00.4-0.4
Ambulatory time after self-admin1.01.14.10.51.1-1.40.8-0.8-0.5-0.81.8-2.0-0.40.2-0.4
Total heroin consumption0.50.62.1-0.70.9-1.10.6-0.6-1.4-0.8-0.0-0.5-0.7-0.40.0
Area under the delay curve0.70.72.1-0.91.5-1.11.2-1.2-0.5-0.60.4-0.4-0.8-0.1-0.5
Delay disc. indifference point, 0s delay0.40.51.30.10.4-0.11.1-1.10.30.8-0.50.60.40.80.8
Delay disc. indifference point, 16s delay1.11.12.7-0.91.6-1.40.8-0.8-0.5-1.11.1-1.1-1.1-0.6-1.2
Delay disc. indifference point, 2s delay2.62.96.5-2.12.4-1.92.6-2.6-1.8-0.8-0.90.9-1.6-0.40.0
Delay disc. indifference point, 24s delay1.71.64.1-1.21.7-1.50.3-0.3-0.5-1.70.5-0.5-1.7-1.4-2.0
Delay disc. indifference point, 4s delay0.70.81.8-0.00.8-0.41.3-1.3-0.40.21.2-1.20.31.10.7
Delay disc. indifference point, 8s delay0.40.41.1-1.00.8-0.21.0-1.0-0.40.2-0.40.5-0.40.40.4
Delay discount exponential model param0.80.92.41.0-1.61.3-1.21.20.70.8-0.40.41.00.30.7
Delay discount hyperbolic model param0.80.92.41.1-1.51.2-1.41.40.70.6-0.20.10.90.20.4
Fecal boli incidents, locomotor time 10.30.41.00.70.7-0.80.3-0.30.5-0.31.0-1.0-0.0-0.3-0.6
Change in fecal boli incidents, locomotor task0.20.20.50.10.00.50.2-0.20.70.20.7-0.30.60.6-0.2
Time >=10cm from walls, locomotor time 11.81.93.41.80.2-0.21.7-1.70.81.31.1-1.11.81.71.6
Bouts of movement, locomotor time 10.70.72.60.1-1.31.6-1.11.10.80.8-0.40.50.60.30.3
Total resting periods, locomotor time 10.50.62.40.0-1.11.5-0.90.90.70.8-0.30.40.60.40.3
Rest time, locomotor task time 10.40.41.3-0.5-0.50.80.1-0.1-0.20.7-1.11.10.20.31.0
Distance moved, locomotor task time 10.40.41.0-0.40.3-0.4-0.50.5-0.4-0.90.6-0.6-0.7-0.6-1.0
Vertical activity count, locomotor time 10.60.61.5-0.60.8-0.80.2-0.2-0.9-1.01.1-1.2-0.7-0.3-0.7
Time >=10cm from walls, locomotor time 20.40.42.20.4-0.20.2-0.10.1-0.50.01.2-1.50.50.60.6
Bouts of movement, locomotor time 20.60.71.50.6-1.01.2-1.21.21.10.60.3-0.10.60.4-0.1
Total resting periods, locomotor time 20.70.81.80.7-1.11.4-0.90.91.20.90.40.00.90.70.3
Rest time, locomotor task time 21.61.83.91.6-0.20.71.3-1.31.72.00.10.11.81.81.6
Distance moved, locomotor task time 20.70.82.7-0.7-0.90.6-1.61.6-1.0-0.70.0-0.3-0.5-0.4-0.4
Vertical activity count, locomotor time 22.02.25.3-1.7-0.80.3-2.32.3-1.6-1.6-0.70.2-1.5-1.7-1.2
Weight adjusted by age0.50.61.61.30.5-0.40.9-0.91.20.50.8-0.70.70.60.1
Seeking ratio, delayed vs. immediate footshock0.50.61.80.7-1.00.7-1.41.41.00.1-0.00.20.4-0.0-0.7
Locomotion in novel chamber1.51.85.60.31.6-1.71.6-1.6-0.8-0.72.0-2.4-0.10.8-0.1
Locomotion in novel chamber post-restriction2.93.47.7-1.72.8-2.81.7-1.7-1.8-1.90.4-0.8-2.3-1.5-1.3
Progressive ratio0.50.61.80.11.2-1.21.4-1.4-0.2-0.10.2-0.4-0.30.30.1
Food seeking constrained by brief footshock1.11.44.0-0.4-0.0-0.8-1.31.3-0.7-1.6-0.10.2-1.4-2.0-1.7
Seeking ratio, punishment vs. effort0.81.03.4-0.3-0.90.4-1.81.8-0.3-0.90.00.3-0.5-1.3-1.0
Run reversals in cocaine runway, females1.41.43.10.2-1.11.5-1.61.60.80.11.8-1.50.80.6-0.5
Run reversals in cocaine runway, males0.70.73.00.20.8-0.60.5-0.5-0.2-0.31.7-1.7-0.10.6-0.2
Latency to leave start box in cocaine runway0.20.30.60.6-0.10.20.2-0.20.30.40.8-0.70.60.80.5
Latency to leave start box in cocaine runway, F1.01.14.30.80.5-0.30.7-0.70.10.22.0-2.10.71.20.5
Latency to leave start box in cocaine runway, M0.80.82.70.1-1.21.0-0.60.60.50.7-1.61.60.5-0.20.4
Cd content in liver2.93.26.22.4-1.91.7-0.30.32.42.4-0.81.22.51.91.7
Co content in liver1.21.44.32.1-1.71.1-0.80.81.61.1-0.40.51.50.50.5
Cu content in liver0.40.50.9-0.9-0.50.6-0.90.9-0.3-0.2-1.00.8-0.6-0.8-0.3
Fe content in liver0.60.72.40.1-0.90.8-0.10.10.21.0-1.61.50.50.41.2
K content in liver1.61.63.0-1.21.5-1.71.4-1.4-1.6-0.8-1.20.9-1.3-1.00.0
Mg content in liver1.61.69.2-0.6-0.30.20.4-0.4-0.40.6-3.02.8-0.2-0.70.9
Mn content in liver2.12.45.5-1.81.0-0.81.9-1.9-1.80.3-2.32.2-0.70.11.5
Na content in liver0.91.02.5-0.50.7-1.11.2-1.2-1.0-0.3-1.61.1-0.9-1.00.3
Rb content in liver2.43.07.61.1-0.90.91.3-1.30.92.4-2.12.11.91.82.8
Se content in liver0.91.12.11.20.2-0.21.4-1.41.11.3-0.90.90.91.11.1
Sr content in liver1.31.23.2-0.81.3-1.10.7-0.7-1.1-1.21.6-1.8-0.9-0.3-0.8
Zn content in liver1.82.06.1-0.92.0-2.02.5-2.5-1.2-0.5-0.2-0.1-1.0-0.20.1