Hub : Genes

Atf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000061088 0.06 0.04 2.0e-07 0.03 0.05 0.04 0.04 3.0e-04 3.7e-06 1.7e-05 1.5e-05
2 Adipose intron excision ratio chr7:131385452:131386968 0.03 0.02 1.3e-04 0.03 0.03 0.02 0.03 6.0e-04 7.5e-04 6.0e-03 7.3e-04
3 Adipose intron excision ratio chr7:131392102:131396775 0.02 0.02 3.3e-03 0.02 0.02 0.01 0.02 2.4e-03 3.8e-03 2.5e-02 5.9e-03
4 Adipose mRNA stability ENSRNOG00000061088 0.14 0.07 0.0e+00 0.18 0.18 0.18 0.18 1.0e-19 7.1e-20 1.7e-19 9.0e-20
5 BLA mRNA stability ENSRNOG00000061088 0.13 0.11 5.0e-06 0.09 0.1 0.07 0.09 2.2e-05 3.8e-06 8.8e-05 9.8e-06
6 Brain mRNA stability ENSRNOG00000061088 0.12 0.06 4.7e-15 0.16 0.17 0.15 0.16 1.1e-14 1.4e-15 1.8e-13 6.6e-15
7 Liver intron excision ratio chr7:131392102:131396775 0.07 0.05 9.4e-10 0.08 0.09 0.09 0.09 2.4e-09 9.6e-10 4.4e-10 4.7e-10
8 Liver mRNA stability ENSRNOG00000061088 0.1 0.06 1.3e-15 0.14 0.14 0.14 0.14 7.4e-15 8.6e-15 5.6e-15 6.9e-15
9 NAcc mRNA stability ENSRNOG00000061088 0.09 0.06 5.6e-07 0.1 0.09 0.08 0.05 9.9e-08 2.4e-07 1.3e-06 1.0e-04
10 OFC mRNA stability ENSRNOG00000061088 0.2 0.12 2.1e-04 0.09 0.1 0.11 0.09 3.2e-03 1.9e-03 1.4e-03 3.2e-03
11 PL mRNA stability ENSRNOG00000061088 0.16 0.09 4.6e-14 0.17 0.15 0.19 0.14 5.8e-13 1.2e-11 2.3e-14 5.7e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail5.317.324.33.7-4.5-4.33.93.84.0-4.34.24.53.54.9
BMI without tail0.71.42.11.1-1.3-1.40.90.61.1-0.91.41.31.31.2
Body weight5.222.125.94.6-4.8-5.14.64.34.7-4.35.04.84.45.1
Epididymis fat weight0.10.21.20.7-0.2-0.50.1-0.50.30.40.40.21.1-0.0
Glucose0.10.10.3-0.5-0.00.2-0.5-0.5-0.40.2-0.3-0.0-0.4-0.1
Heart weight0.10.10.50.5-0.4-0.10.30.10.4-0.10.20.40.70.5
Left kidney weight1.23.44.41.9-2.0-1.81.71.51.9-1.61.82.02.02.1
Right kidney weight2.57.29.92.5-2.9-2.62.52.32.6-2.62.72.92.53.2
Tail length0.10.20.70.30.3-0.3-0.2-0.5-0.00.80.3-0.40.5-0.7
Length with tail1.45.17.02.6-1.9-2.62.42.12.4-1.52.62.02.61.8
Length without tail4.18.99.93.0-2.8-3.13.13.13.1-2.73.12.82.83.1
Liver weight, left1.42.33.81.8-1.2-1.71.61.31.6-0.91.71.21.91.3
Liver weight, right1.62.74.61.8-1.8-1.61.61.11.7-1.01.61.82.11.7
Parametrial fat weight0.91.83.1-1.21.31.2-1.4-1.8-1.41.6-1.2-1.3-0.9-1.3
Retroperitoneal fat weight0.93.04.5-1.51.71.4-1.8-2.1-1.72.0-1.6-1.7-1.3-2.1
Intraocular pressure4.36.17.3-2.42.12.7-2.6-2.7-2.52.6-2.7-2.1-2.1-2.6
Extensor digitorum longus weight5.321.129.83.8-4.9-4.54.54.94.4-5.34.54.83.05.5
Soleus weight1.02.93.21.8-1.8-1.81.71.61.8-1.51.81.81.81.6
Tibialis anterior weight4.214.524.02.7-4.0-3.83.64.23.5-4.93.84.01.74.5
Tibia length4.111.516.23.9-3.1-3.73.42.83.6-2.33.73.14.03.3
Number of licking bursts1.21.42.8-1.21.50.7-1.0-0.8-1.10.8-0.7-1.7-1.5-1.3
Food consumed during 24 hour testing period2.12.54.11.7-1.7-1.51.51.01.6-1.31.51.62.01.8
Times rat made contact with spout0.10.10.30.2-0.1-0.2-0.0-0.20.1-0.10.20.20.30.6
Mean time between licks in bursts0.40.61.6-0.51.10.7-0.4-0.1-0.50.6-0.6-1.3-0.6-1.0
Mean num. licks in bursts0.70.92.31.0-1.3-0.40.70.20.8-0.40.41.41.51.1
Std. dev. time between licks in bursts1.61.93.3-1.31.71.2-1.3-1.2-1.31.3-1.2-1.8-1.3-1.7
Water consumed over 24 hours0.20.20.60.10.30.3-0.3-0.8-0.20.8-0.3-0.20.60.0
Indifference point 0 sec5.08.110.2-2.82.43.1-3.1-3.2-2.92.9-3.2-2.3-2.3-2.8
Indifference point AUC0.20.20.9-0.60.40.4-0.4-0.1-0.50.0-0.5-0.5-0.9-0.3
Indifference point function ln k4.76.78.42.7-2.7-2.32.62.32.6-2.12.52.72.92.9
Indifference point function log k4.76.78.42.7-2.7-2.32.62.32.6-2.12.52.72.92.9
Delay discounting total patch changes 0 sec4.77.69.9-2.72.43.0-3.0-3.2-2.82.9-3.1-2.3-2.1-2.8
Delay discounting total patch changes 12 sec5.06.77.7-2.72.32.7-2.7-2.7-2.72.3-2.8-2.3-2.5-2.6
Delay discounting total patch changes 18 sec6.78.99.8-3.03.03.0-3.1-3.0-3.02.8-3.1-3.0-2.8-3.1
Delay discounting total patch changes 24 sec3.74.75.2-2.22.12.1-2.3-2.3-2.22.1-2.2-2.0-2.0-2.3
Delay discounting total patch changes 6 sec6.09.211.2-3.12.83.2-3.2-3.1-3.12.9-3.3-2.7-2.9-2.9
Delay discounting time to switch 0 sec2.13.23.9-1.91.71.7-1.9-1.7-1.91.4-1.7-1.8-2.0-1.9
Delay discounting water rate 0 sec3.45.56.72.4-2.3-2.42.32.02.4-1.92.42.42.52.6
Delay discounting water rate 12 sec2.23.34.92.1-1.5-1.71.91.71.9-1.41.91.62.21.8
Delay discounting water rate 18 sec0.30.30.60.7-0.4-0.50.70.60.6-0.40.50.50.80.5
Delay discounting water rate 24 sec3.85.26.02.4-2.2-2.12.42.32.4-2.02.22.32.42.4
Delay discounting water rate 6 sec5.37.89.33.0-2.6-2.82.92.62.9-2.32.92.63.13.0
Locomotor activity0.81.21.6-1.20.91.2-1.3-1.2-1.21.2-1.1-1.0-1.1-0.8
Locomotor testing distance2.44.04.8-2.11.72.1-2.2-2.2-2.12.1-2.1-1.7-1.8-1.7
Locomotor testing rearing1.42.23.7-1.51.01.7-1.8-1.9-1.61.6-1.7-1.0-1.0-1.3
Light reinforcement 10.91.63.1-1.31.31.1-1.1-0.8-1.21.0-1.2-1.4-1.4-1.8
Light reinforcement 20.00.00.10.1-0.0-0.20.20.40.1-0.20.20.1-0.1-0.3
Reaction time number correct1.11.64.21.6-1.4-0.91.20.71.3-0.60.91.42.01.4
Reaction time mean minus median4.45.86.8-2.52.42.4-2.6-2.5-2.52.3-2.4-2.3-2.3-2.3
Reaction time mean minus median AUC3.03.84.8-2.21.82.1-2.2-2.0-2.11.7-2.1-1.7-2.1-1.7
Reaction time num false alarms1.41.92.6-1.51.31.5-1.3-1.1-1.41.0-1.6-1.3-1.6-1.4
Reaction time num false alarms AUC1.52.13.4-1.71.31.6-1.4-1.1-1.50.9-1.7-1.3-1.8-1.3
Reaction time trials correct on left1.11.64.21.6-1.4-0.91.20.71.3-0.60.91.42.01.4
Reaction time trials on left0.91.33.61.4-1.2-0.81.00.61.1-0.50.81.31.91.2
Reaction time mean0.60.81.4-0.81.00.7-0.9-1.0-0.91.2-0.7-1.0-0.6-0.9
Reaction time mean AUC0.30.41.0-0.50.70.5-0.7-0.8-0.61.0-0.5-0.7-0.4-0.7
Median of all reaction times0.00.10.30.00.2-0.1-0.1-0.2-0.10.60.1-0.30.1-0.2
Reaction time omissions7.510.212.2-3.13.13.1-3.3-3.2-3.23.5-3.3-3.1-2.8-3.3
Reaction time false alarm rate1.82.55.7-1.91.51.5-1.4-0.9-1.70.8-1.6-1.5-2.4-1.5
Reaction time premature initiation rate4.25.66.7-2.32.42.4-2.5-2.6-2.42.3-2.4-2.3-1.9-2.5
Reaction time premature initiations1.82.64.2-1.31.51.8-1.7-2.1-1.61.9-1.8-1.4-0.7-1.5
Std. dev. reaction times4.15.66.3-2.52.42.3-2.5-2.4-2.52.3-2.3-2.3-2.4-2.3
Reaction time trials completed0.91.33.61.4-1.2-0.81.00.61.1-0.50.81.31.91.2
Reaction time trials AUC1.52.24.81.7-1.6-1.11.40.91.5-0.81.11.72.21.6
Social response proportion0.10.10.30.10.1-0.1-0.2-0.5-0.10.60.1-0.10.3-0.2
Social responses3.64.75.6-2.42.12.0-2.3-2.2-2.31.9-2.1-2.0-2.3-2.1
Social time0.20.31.00.8-0.3-0.70.50.30.60.10.60.31.00.3
Conditioned locomotion0.10.10.2-0.10.40.4-0.2-0.2-0.20.4-0.4-0.40.0-0.4
Cocaine response after cond. corrected0.00.00.2-0.20.30.2-0.00.1-0.1-0.1-0.1-0.3-0.4-0.0
Cocaine response after cond. not corrected0.20.30.3-0.50.50.6-0.5-0.4-0.50.5-0.5-0.5-0.6-0.3
Cocaine response before conditioning1.41.83.2-1.21.01.4-1.5-1.7-1.31.8-1.4-1.1-0.7-1.2
Saline control response0.10.10.40.2-0.20.1-0.1-0.40.00.4-0.10.20.60.1
Condit. Reinf. active minus inactive responses1.51.82.91.1-1.6-1.21.21.31.2-1.41.31.61.01.7
Condit. Reinf. active-inactive response ratio1.21.32.21.0-1.3-1.11.11.01.1-1.01.21.30.91.5
Condit. Reinf. active responses0.30.40.90.4-1.0-0.30.50.50.5-0.60.40.90.40.8
Condit. Reinf. inactive responses0.60.81.2-1.00.51.1-1.0-0.9-0.90.7-1.0-0.5-0.9-0.8
Condit. Reinf. lever presses0.00.10.30.10.20.0-0.1-0.2-0.00.60.0-0.20.3-0.4
Condit. Reinf. lever reinforcers received0.00.10.3-0.0-0.50.10.00.10.1-0.10.00.50.10.4
Pavlov. Cond. lever latency1.01.42.11.0-1.4-0.81.21.11.1-1.40.91.41.01.5
Pavlov. Cond. magazine entry latency0.40.51.3-0.31.10.3-0.4-0.5-0.50.9-0.3-1.1-0.3-1.0
Pavlov. Cond. change in total contacts0.71.01.60.7-1.0-1.30.91.10.9-1.21.31.00.30.8
Pavlov. Cond. index score0.60.81.6-0.71.30.4-0.8-0.7-0.81.1-0.5-1.3-0.8-1.3
Pavlov. Cond. latency score0.60.71.4-0.71.20.4-0.7-0.7-0.71.0-0.4-1.2-0.7-1.2
Pavlov. Cond. lever contacts1.01.42.5-0.91.50.8-1.1-1.1-1.11.5-0.8-1.5-0.9-1.6
Pavlov. Cond. magazine entry number0.10.10.20.1-0.50.00.10.10.1-0.4-0.00.50.10.4
Pavlov. Cond. intertrial magazine entries1.11.53.7-1.00.61.5-1.5-1.9-1.21.4-1.5-0.5-0.5-0.9
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.40.90.1-0.5-0.4-0.50.7-0.1-0.9-0.5-0.9
Pavlov. Cond. response bias0.60.81.6-0.61.20.5-0.8-0.8-0.81.2-0.5-1.2-0.6-1.3
Conditioned reinforcement - actives1.31.31.6-1.21.21.1-1.1-0.9-1.21.1-1.1-1.2-1.2-1.3
Conditioned reinforcement - inactives1.72.02.9-1.31.31.3-1.4-1.4-1.41.7-1.3-1.3-1.3-1.5
Conditioned locomotion0.20.20.4-0.30.50.4-0.4-0.5-0.40.5-0.4-0.5-0.3-0.6
Intermittent access intake day 1-15 change0.30.30.8-0.20.50.5-0.5-0.7-0.40.9-0.5-0.50.1-0.7
Intermittent access intake escalation0.20.10.60.20.30.3-0.2-0.5-0.10.8-0.2-0.30.5-0.6
Intermittent access intake escalation 20.20.20.6-0.00.30.3-0.3-0.6-0.20.8-0.3-0.30.2-0.6
Intermitt. access day 1 inactive lever presses0.30.30.6-0.40.40.6-0.6-0.7-0.50.8-0.5-0.4-0.3-0.7
Intermitt. access day 15 inactive lever presses0.20.30.7-0.20.50.4-0.4-0.5-0.40.8-0.5-0.5-0.0-0.8
Intermitt. access escalation Index0.80.71.8-1.10.70.8-0.8-0.5-0.90.1-0.8-0.7-1.3-0.7
Intermittent access day 1 total infusions1.51.72.0-1.21.41.2-1.2-1.2-1.31.4-1.3-1.4-1.1-1.4
Intermittent access day 15 total infusions2.12.43.6-1.31.61.5-1.5-1.6-1.51.8-1.5-1.6-1.0-1.9
Intermittent access terminal intake (last 3 days)2.02.23.5-1.31.61.4-1.4-1.5-1.41.7-1.4-1.6-1.1-1.9
Intermittent access total infusions1.92.13.0-1.21.51.3-1.4-1.5-1.41.7-1.4-1.5-1.1-1.7
Intermittent access day 1 locomotion1.91.93.5-1.11.41.3-1.3-1.4-1.31.6-1.4-1.4-0.9-1.9
Intermittent access day 15 total locomotion1.31.32.5-0.81.11.0-1.1-1.4-1.11.6-1.0-1.1-0.4-1.6
Intermittent access total locomotion4.14.76.6-1.92.22.1-2.2-2.3-2.12.4-2.1-2.2-1.6-2.6
Intermittent access standard deviation0.20.20.70.20.20.2-0.1-0.4-0.00.8-0.2-0.20.5-0.7
Cocaine induced anxiety0.80.91.81.1-0.8-1.00.90.61.0-0.61.00.81.41.1
Post-drug Anxiety4.95.47.02.5-2.2-2.32.32.12.4-2.02.32.22.62.5
Baseline Anxiety0.80.81.10.9-1.1-0.80.91.00.9-0.90.81.10.80.7
Lifetime Intake2.83.14.7-1.51.81.6-1.7-1.8-1.72.1-1.7-1.8-1.3-2.2
Incentive Sensitization - Responses0.50.50.70.7-0.7-0.80.60.60.7-0.40.80.70.80.8
Incentive Sensitization - Breakpoint0.40.40.60.6-0.6-0.80.60.60.6-0.40.80.60.70.7
Progressive ratio test 1 active lever presses9.29.512.8-2.83.03.0-3.1-3.1-3.13.3-3.1-3.0-2.6-3.6
Progressive ratio test 1 breakpoint7.88.011.0-2.62.82.7-2.8-2.8-2.83.0-2.8-2.8-2.5-3.3
Progressive ratio test 1 inactive lever presses2.42.64.3-1.51.51.5-1.6-1.6-1.61.8-1.5-1.5-1.4-2.1
Progressive ratio test 2 active lever presses2.12.23.4-1.31.51.3-1.5-1.6-1.51.8-1.4-1.5-1.1-1.8
Progressive ratio test 2 breakpoint2.12.33.4-1.31.51.3-1.5-1.7-1.51.8-1.4-1.5-1.1-1.8
Progressive ratio test 2 inactive lever presses1.41.63.0-0.91.21.2-1.2-1.4-1.21.7-1.2-1.2-0.7-1.6
Total sessions with >9 infusions1.71.93.4-1.21.31.2-1.3-1.4-1.31.8-1.3-1.3-1.0-1.9
Short access day 1 total inactive lever presses1.21.32.1-1.11.01.1-1.1-1.2-1.21.1-1.1-1.0-1.0-1.4
Short access day 10 total inactive lever presses0.10.10.30.4-0.3-0.20.20.00.3-0.00.30.30.60.1
Short access day 1 total infusions0.70.81.5-0.70.80.7-0.8-0.9-0.81.2-0.7-0.8-0.6-1.2
Short access day 10 total infusions3.43.85.4-1.72.01.9-1.8-1.9-1.92.1-1.9-2.0-1.6-2.3
Short access total infusions2.22.44.0-1.31.51.4-1.5-1.6-1.51.9-1.5-1.5-1.1-2.0
Short access day 1 locomotion0.20.20.6-0.50.40.2-0.5-0.4-0.50.4-0.3-0.4-0.5-0.8
Short access day 10 total locomotion0.20.20.5-0.30.40.4-0.5-0.5-0.40.6-0.5-0.4-0.1-0.7
Short access total locomotion0.70.81.8-0.70.80.8-0.8-0.8-0.81.0-0.8-0.8-0.6-1.3
Compulsive drug intake2.42.43.01.3-1.7-1.61.51.51.4-1.71.61.71.11.6
One hour access (0.3 mA shock)0.10.10.20.3-0.4-0.40.30.20.3-0.10.40.40.20.2
One hour access (shock baseline)0.00.00.10.10.1-0.0-0.0-0.10.00.30.0-0.10.2-0.2
Number of responses in last shaping day0.20.20.30.5-0.4-0.40.60.60.5-0.60.40.40.50.6
Context. condit. distance diff. score0.40.50.90.8-0.8-0.80.60.30.7-0.70.80.80.90.6
Locomotion velocity, session 13.94.25.3-2.21.82.3-2.2-2.1-2.21.9-2.3-1.8-2.1-1.5
Locomotion distance, session 12.93.84.7-2.11.82.2-2.0-1.7-2.01.8-2.2-1.8-2.1-1.6
Locomotion velocity, session 20.30.40.5-0.60.60.7-0.6-0.7-0.60.6-0.7-0.6-0.5-0.7
Locomotion distance, session 23.65.15.5-2.32.32.2-2.2-1.9-2.32.2-2.3-2.3-2.3-2.3
Locomotion velocity, session 34.95.76.5-2.22.52.3-2.4-2.5-2.42.5-2.4-2.5-2.0-2.4
Locomotion distance, session 33.03.35.0-1.41.71.9-1.9-2.2-1.82.2-2.0-1.7-0.9-1.9
Stereotopy head waving bouts, day 30.10.20.9-0.40.40.00.00.4-0.2-0.3-0.1-0.4-0.90.1
Stereotopy head waving duration, day 30.30.30.8-0.50.90.3-0.3-0.1-0.40.5-0.4-0.9-0.8-0.6
Locomotion velocity, session 73.43.74.8-1.62.02.0-2.0-2.2-1.92.1-2.0-2.0-1.2-2.0
Locomotion distance, session 74.35.57.0-2.02.42.3-2.4-2.7-2.32.5-2.3-2.4-1.6-2.6
Stereotopy head waving bouts, day 70.70.81.80.5-0.9-0.80.91.20.8-1.30.80.90.11.4
Stereotopy head waving duration, day 71.31.52.90.8-1.2-1.11.21.51.1-1.61.21.20.41.7
Locomotion velocity, session 80.40.50.7-0.80.70.7-0.8-0.7-0.70.6-0.7-0.7-0.9-0.7
Locomotion distance, session 80.91.41.7-1.21.11.2-1.3-1.3-1.21.1-1.2-1.1-1.0-1.2
Degree of sensitization distance0.00.00.2-0.1-0.1-0.10.10.20.0-0.40.20.1-0.40.1
Degree of sensitization stereotypy1.31.43.10.7-1.3-0.91.01.21.0-1.61.01.30.31.7
Condit. Reinf. active minus inactive responses0.10.10.2-0.2-0.30.1-0.1-0.2-0.10.0-0.20.3-0.10.5
Condit. Reinf. active-inactive response ratio0.20.30.70.6-0.7-0.30.40.10.5-0.10.30.70.90.6
Condit. Reinf. active responses0.40.51.0-1.00.30.8-0.8-0.7-0.80.4-0.8-0.3-1.0-0.2
Condit. Reinf. inactive responses2.63.15.5-2.11.71.7-1.8-1.4-1.91.2-1.7-1.7-2.3-1.5
Incentive salience index mean0.20.20.70.1-0.8-0.30.20.20.3-0.50.20.80.10.9
Condit. Reinf. lever presses0.81.12.00.7-1.3-0.90.91.10.9-1.40.91.30.51.4
Time in familiar zone, hab. session 10.10.10.30.0-0.4-0.20.20.20.1-0.60.20.4-0.10.6
Time in novel zone, hab. session 10.00.00.10.00.3-0.10.10.20.00.20.1-0.3-0.0-0.4
Total zone transitions, hab. session 10.10.21.1-0.70.10.2-0.20.3-0.3-0.4-0.2-0.1-1.10.1
Total locomotion distance, hab. session 10.40.51.0-0.90.70.8-0.7-0.4-0.80.5-0.8-0.7-1.0-0.4
Locomotion velocity, hab. session 10.20.30.6-0.70.50.6-0.6-0.3-0.60.4-0.7-0.5-0.8-0.2
Time in familiar zone, hab. session 22.02.13.21.4-1.6-1.21.41.11.4-1.51.21.61.41.8
Time in novel zone, hab. session 22.22.23.2-1.41.71.3-1.4-1.1-1.41.6-1.4-1.7-1.5-1.8
Total zone transitions, hab. session 20.30.40.6-0.70.80.6-0.6-0.4-0.60.7-0.6-0.8-0.7-0.8
Total locomotion distance, hab. session 20.70.91.2-0.91.10.9-0.8-0.7-0.91.1-0.9-1.1-0.9-1.1
Locomotion velocity, hab. session 20.40.61.0-0.60.90.6-0.6-0.5-0.71.0-0.6-0.9-0.6-1.0
Novel to familiar place preference ratio1.51.62.21.1-1.3-1.41.31.51.3-1.41.41.30.81.2
Novelty place preference1.01.01.40.8-1.0-1.11.01.21.0-1.11.11.00.50.9
Time in novel zone, NPP test0.70.71.10.6-0.9-0.90.81.10.8-1.00.90.90.30.8
Total zone transitions, NPP test2.84.05.2-2.22.11.9-2.0-1.6-2.01.8-2.0-2.1-2.3-1.9
Total locomotion distance, NPP test4.25.86.8-2.42.62.4-2.3-2.0-2.42.4-2.4-2.6-2.4-2.5
Locomotion velocity, NPP test2.84.04.9-2.02.21.9-1.9-1.7-2.02.1-2.0-2.2-2.0-2.1
Pavlov. Cond. lever latency0.50.71.2-0.41.00.8-0.6-0.8-0.71.0-0.8-1.0-0.2-1.1
Pavlov. Cond. magazine entry latency1.21.62.21.1-1.3-1.31.31.41.2-1.51.31.30.91.1
Pavlov. Cond. change in total contacts2.22.33.41.1-1.8-1.51.41.51.4-1.81.51.80.91.7
Pavlov. Cond. index score1.41.82.71.0-1.6-1.41.21.41.2-1.61.31.60.71.5
Pavlov. Cond. latency score1.31.62.60.9-1.6-1.31.11.21.1-1.51.21.60.61.5
Pavlov. Cond. lever contacts0.40.40.80.4-0.9-0.70.50.50.6-0.70.70.90.30.9
Pavlov. Cond. magazine entry number0.60.81.1-0.81.00.9-0.8-0.8-0.91.0-0.9-1.0-0.7-0.7
Pavlov. Cond. intertrial magazine entries4.95.87.0-2.52.12.6-2.5-2.5-2.52.4-2.6-2.1-2.3-2.2
Pavlov. Cond. lever-magazine prob. diff.1.82.22.91.1-1.7-1.61.41.51.4-1.71.51.70.91.7
Pavlov. Cond. response bias0.40.50.70.6-0.8-0.80.70.80.7-0.90.80.80.50.7
Bone: apparent density6.110.113.63.5-3.2-3.03.22.93.3-2.53.13.23.73.0
Bone surface9.216.119.94.3-4.3-3.84.03.64.1-3.43.94.34.54.1
Bone volume8.013.416.74.0-3.7-3.53.73.53.8-3.03.73.74.13.5
Bone: connectivity density3.35.27.52.5-2.4-2.02.31.92.3-1.82.12.42.72.3
Bone: cortical apparent density0.60.71.6-1.00.81.0-0.7-0.2-0.80.6-1.0-0.8-1.3-0.7
Bone: cortical area5.58.410.03.1-3.0-3.02.92.63.0-2.23.03.03.22.8
Bone: cortical porosity0.10.10.80.5-0.2-0.10.2-0.10.30.10.20.20.90.0
Bone: cortical porosity0.10.10.40.30.10.2-0.1-0.30.00.4-0.2-0.10.6-0.3
Bone: cortical thickness1.52.53.01.7-1.7-1.71.61.41.7-1.11.71.71.71.6
Bone: cortical thickness0.20.20.9-0.30.30.3-0.5-0.7-0.40.9-0.4-0.2-0.1-0.3
Bone: cortical tissue density0.71.01.9-1.11.01.2-0.8-0.3-0.90.7-1.2-1.0-1.4-0.9
Bone: elastic displacement8.19.210.3-2.83.13.2-2.9-3.0-3.03.2-3.2-3.1-2.6-3.1
Bone: elastic work0.30.31.1-0.10.80.6-0.3-0.5-0.31.0-0.6-0.80.1-0.6
Bone: endosteal estimation6.614.219.34.2-3.7-3.73.93.43.9-3.13.83.74.43.5
Bone: endosteal perimeter6.313.015.63.9-3.5-3.83.73.53.8-3.03.83.43.93.3
Bone: final force9.816.121.04.4-4.0-4.04.13.64.2-3.14.14.04.64.0
Bone: final moment10.917.924.64.7-4.1-4.24.33.84.4-3.24.34.25.04.1
Bone: marrow area6.213.418.44.0-3.6-3.63.73.33.8-3.03.73.64.33.4
Bone: maximum diameter1.62.93.51.8-1.8-1.91.71.61.8-1.41.91.81.81.5
Bone: maximum force12.221.225.14.9-4.5-4.64.84.44.8-3.94.64.55.04.5
Bone: maximum moment13.423.329.25.3-4.7-4.85.04.65.1-4.04.94.75.44.6
Bone: minimum diameter7.013.015.63.9-3.4-3.73.83.63.8-3.13.73.43.93.3
Bone: periosteal estimation8.617.622.84.6-4.2-4.34.33.84.4-3.34.44.24.83.8
Bone: periosteal perimeter8.614.216.04.0-3.6-4.03.93.73.9-3.24.03.64.03.5
Bone: post-yield work6.99.512.43.4-2.9-3.03.22.93.2-2.73.12.93.52.7
Bone: stiffness16.225.628.75.4-4.8-5.25.35.05.3-4.55.34.95.34.8
Bone: tissue strength1.81.82.31.3-1.4-1.11.41.41.3-1.41.21.41.21.5
Bone: trabecular number3.25.08.32.6-2.3-2.02.31.92.4-1.62.12.32.92.1
Bone: trabecular spacing0.81.01.9-1.21.10.8-1.0-0.8-1.10.7-0.8-1.1-1.4-1.0
Bone: trabecular thickness0.50.61.00.7-1.0-0.60.80.90.8-0.80.61.00.61.0
Bone: trabecular tissue density0.60.82.80.5-0.2-1.01.11.70.8-1.21.00.3-0.10.5
Breakpoint value in progressive ratio session0.10.10.30.3-0.6-0.20.2-0.00.20.10.20.60.4-0.0
Distance traveled before self-admin2.22.42.7-1.61.41.6-1.6-1.6-1.61.2-1.6-1.4-1.6-1.6
Distance traveled after self-admin0.70.71.0-0.70.90.9-0.9-1.0-0.80.8-0.9-0.9-0.6-0.7
Delta time in closed arm before/after self-admin0.10.10.20.4-0.3-0.30.30.20.3-0.40.30.30.4-0.0
Delta time in open arm before/after self-admin3.53.45.0-1.61.91.8-1.9-2.1-1.82.2-1.8-1.9-1.3-1.8
Diff in mean of infusions in LGA sessions1.92.13.11.2-1.7-1.41.31.31.4-1.81.51.71.11.6
Extinction: sum of active levers before priming1.51.52.30.9-1.4-1.21.01.01.1-1.51.21.40.81.5
Active lever presses in extinction session 60.00.00.10.2-0.1-0.10.20.10.20.20.20.10.20.3
Delta distance traveled before/after self-admin0.20.31.00.8-0.2-0.40.40.00.50.20.50.21.00.6
Delta ambulatory time before/after self-admin0.10.20.70.60.0-0.20.2-0.20.30.50.2-0.00.90.3
Time in closed arm before self-admin1.01.12.40.9-1.0-0.91.01.21.0-1.11.01.00.71.6
Time in closed arm after self-admin0.50.51.10.5-0.7-0.70.70.90.7-1.10.70.70.30.7
Time in open arm before self-admin0.20.20.9-0.1-0.3-0.30.30.60.2-1.00.30.2-0.40.2
Time in open arm after self-admin0.30.30.5-0.60.60.5-0.5-0.4-0.60.4-0.5-0.6-0.7-0.4
Sum of active levers in priming session hrs 5-60.70.70.9-0.80.90.9-0.7-0.6-0.80.7-0.8-0.9-0.9-1.0
Time to tail flick, vehicle, before self-admin0.60.60.9-0.90.60.8-0.8-0.7-0.80.6-0.9-0.6-0.9-1.0
Time to tail flick, vehicle, after self-admin0.60.61.00.7-0.8-0.80.80.80.8-0.50.80.80.61.0
Time to tail flick, test, before self-admin0.20.20.4-0.60.50.6-0.4-0.1-0.40.1-0.6-0.5-0.6-0.1
Time to tail flick, test, after self-admin0.70.71.21.0-0.8-0.70.90.70.9-0.60.80.81.10.8
Delta time to tail flick, vehicle, before/after SA0.90.81.21.0-0.9-1.00.90.70.9-0.41.00.91.11.1
Delta time to tail flick, test, before/after SA0.90.81.21.1-0.9-0.90.90.71.0-0.51.00.91.10.7
Ambulatory time before self-admin3.84.04.9-2.11.82.1-2.1-2.0-2.11.7-2.1-1.8-2.0-2.2
Ambulatory time after self-admin1.82.02.7-1.11.41.5-1.4-1.6-1.41.4-1.5-1.5-1.0-1.6
Total heroin consumption1.21.52.41.4-1.3-1.21.10.81.2-0.91.21.31.51.2
Area under the delay curve0.91.01.31.0-0.9-1.11.11.11.1-0.91.10.90.90.9
Delay disc. indifference point, 0s delay1.61.82.11.5-1.2-1.41.41.41.4-1.21.41.21.31.0
Delay disc. indifference point, 16s delay0.90.91.01.0-1.0-1.00.90.81.0-0.80.91.01.00.9
Delay disc. indifference point, 2s delay2.02.23.71.1-1.4-1.51.51.91.4-1.91.51.30.71.7
Delay disc. indifference point, 24s delay0.60.61.00.7-0.6-0.80.80.80.8-0.90.70.60.61.0
Delay disc. indifference point, 4s delay1.01.01.21.0-0.9-1.11.11.11.1-0.81.10.91.01.0
Delay disc. indifference point, 8s delay1.21.21.71.3-1.0-1.31.21.01.2-0.81.21.01.30.9
Delay discount exponential model param0.91.01.2-1.00.81.1-1.1-1.1-1.00.9-1.1-0.8-0.9-0.9
Delay discount hyperbolic model param1.01.11.5-1.00.91.2-1.1-1.2-1.11.0-1.1-0.9-0.9-1.0
Fecal boli incidents, locomotor time 10.80.91.8-0.80.80.9-1.0-1.3-1.01.1-0.9-0.9-0.5-1.0
Change in fecal boli incidents, locomotor task0.20.20.50.2-0.1-0.30.50.70.4-0.40.30.20.00.6
Time >=10cm from walls, locomotor time 10.40.40.6-0.50.80.5-0.6-0.7-0.60.6-0.6-0.8-0.5-0.7
Bouts of movement, locomotor time 10.00.00.1-0.1-0.00.00.10.20.0-0.20.00.0-0.20.2
Total resting periods, locomotor time 10.40.40.8-0.70.70.7-0.6-0.5-0.70.6-0.7-0.7-0.9-0.6
Rest time, locomotor task time 10.70.70.9-0.90.90.9-0.9-0.8-0.90.8-0.9-0.9-0.9-0.8
Distance moved, locomotor task time 10.00.00.1-0.10.00.1-0.10.0-0.1-0.1-0.0-0.1-0.2-0.2
Vertical activity count, locomotor time 11.01.11.41.0-1.2-0.91.01.01.0-1.11.01.10.91.0
Time >=10cm from walls, locomotor time 20.50.50.8-0.60.70.6-0.7-0.7-0.70.8-0.7-0.7-0.5-0.9
Bouts of movement, locomotor time 23.13.33.61.9-1.7-1.81.91.81.9-1.81.91.71.81.8
Total resting periods, locomotor time 23.63.84.11.9-1.8-1.92.02.02.0-2.02.01.91.82.0
Rest time, locomotor task time 20.10.10.2-0.40.50.3-0.3-0.2-0.30.3-0.3-0.4-0.4-0.3
Distance moved, locomotor task time 20.10.10.2-0.40.10.4-0.3-0.2-0.30.1-0.4-0.2-0.4-0.3
Vertical activity count, locomotor time 20.10.10.30.3-0.5-0.20.30.30.3-0.50.20.40.30.4
Weight adjusted by age0.30.30.80.2-0.5-0.40.50.80.4-0.90.40.5-0.10.7
Seeking ratio, delayed vs. immediate footshock0.91.01.70.9-1.0-0.91.01.01.0-1.10.91.00.91.3
Locomotion in novel chamber2.93.64.01.8-2.0-2.01.91.91.9-1.82.01.91.71.9
Locomotion in novel chamber post-restriction0.40.51.00.9-0.7-0.70.70.50.7-0.30.70.71.00.5
Progressive ratio1.21.41.8-1.21.31.1-1.1-1.0-1.21.0-1.1-1.3-1.2-1.2
Food seeking constrained by brief footshock2.22.73.6-1.61.91.6-1.6-1.6-1.61.4-1.7-1.9-1.5-1.7
Seeking ratio, punishment vs. effort0.10.10.20.4-0.3-0.30.30.30.4-0.40.30.40.40.3
Run reversals in cocaine runway, females0.30.30.90.8-0.4-0.40.60.30.6-0.30.50.41.00.8
Run reversals in cocaine runway, males0.60.61.2-1.00.70.9-0.8-0.5-0.80.3-0.9-0.7-1.1-0.6
Latency to leave start box in cocaine runway0.10.10.2-0.30.10.10.00.4-0.1-0.4-0.10.0-0.50.1
Latency to leave start box in cocaine runway, F1.71.93.6-1.71.31.4-1.3-0.8-1.50.7-1.4-1.3-1.9-1.2
Latency to leave start box in cocaine runway, M2.52.43.11.5-1.6-1.61.61.51.6-1.41.61.61.51.7
Cd content in liver0.50.60.8-0.60.90.7-0.7-0.7-0.70.7-0.7-0.9-0.6-0.9
Co content in liver0.10.10.5-0.4-0.20.1-0.5-0.7-0.40.2-0.10.2-0.40.2
Cu content in liver0.40.40.90.7-0.8-0.50.50.30.6-0.50.60.81.00.7
Fe content in liver1.21.42.3-1.11.40.9-1.1-1.0-1.11.4-0.9-1.4-1.1-1.5
K content in liver0.00.00.1-0.2-0.00.1-0.2-0.3-0.20.1-0.20.0-0.20.4
Mg content in liver0.10.10.2-0.50.30.3-0.4-0.4-0.40.2-0.4-0.3-0.50.2
Mn content in liver0.30.30.80.3-0.7-0.40.50.50.5-0.80.30.70.40.9
Na content in liver0.10.10.3-0.40.10.4-0.5-0.5-0.40.4-0.3-0.1-0.30.1
Rb content in liver1.62.03.0-1.41.11.5-1.6-1.7-1.51.7-1.5-1.1-1.2-1.2
Se content in liver1.51.82.6-1.51.21.2-1.5-1.4-1.51.0-1.3-1.2-1.6-1.2
Sr content in liver0.10.10.30.30.00.0-0.0-0.20.10.4-0.0-0.00.5-0.3
Zn content in liver2.32.52.9-1.61.51.5-1.7-1.7-1.71.5-1.5-1.5-1.5-1.7