Hub : Genes

Esyt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000060753 0.11 0.07 6.4e-08 0.06 0.06 0.06 0.06 2.9e-07 1.3e-07 3.8e-07 4.2e-07
2 Adipose mRNA stability ENSRNOG00000060753 0.18 0.14 1.5e-10 0.02 0.08 0.07 0.07 1.6e-03 3.5e-09 6.1e-08 4.4e-08
3 BLA gene expression ENSRNOG00000060753 0.18 0.12 3.4e-09 0.17 0.17 0.17 0.16 2.6e-09 2.9e-09 1.8e-09 3.6e-09
4 Brain mRNA stability ENSRNOG00000060753 0.11 0.07 1.1e-07 0.05 0.07 0.06 0.06 1.1e-05 6.4e-07 1.4e-06 2.3e-06
5 IL gene expression ENSRNOG00000060753 0.16 0.11 1.0e-02 0.02 -0.01 -0.01 -0.01 1.2e-01 6.8e-01 9.2e-01 5.8e-01
6 Liver gene expression ENSRNOG00000060753 0.06 0.04 3.7e-05 0.01 0.03 0.03 0.03 1.7e-02 9.6e-05 1.1e-04 5.7e-04
7 Liver intron excision ratio chr7:931043:935331 0.23 0.13 0.0e+00 0.13 0.16 0.15 0.16 3.0e-14 2.1e-17 8.8e-17 6.2e-17
8 Liver intron excision ratio chr7:932781:935331 0.07 0.05 7.3e-07 0.06 0.05 0.05 0.05 5.9e-07 1.7e-06 1.8e-06 1.4e-06
9 Liver mRNA stability ENSRNOG00000060753 0.08 0.05 4.4e-06 0.02 0.05 0.05 0.05 4.6e-03 2.3e-06 2.2e-06 3.9e-06
10 NAcc gene expression ENSRNOG00000060753 0.18 0.1 2.6e-15 0.21 0.21 0.21 0.21 7.9e-16 1.5e-15 1.9e-15 8.7e-16
11 OFC gene expression ENSRNOG00000060753 0.26 0.16 1.2e-04 0.15 0.13 0.13 0.14 2.2e-04 5.5e-04 5.5e-04 3.1e-04
12 PL gene expression ENSRNOG00000060753 0.18 0.11 7.2e-14 0.15 0.16 0.16 0.17 1.2e-11 3.5e-12 2.3e-12 4.7e-13
13 PL mRNA stability ENSRNOG00000060753 0.07 0.05 3.1e-05 0.04 0.04 0.05 0.04 2.4e-04 2.4e-04 2.1e-04 5.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail5.116.726.30.62.6-5.03.4-5.01.93.4-5.12.9-4.9-5.0-4.95.1
BMI without tail1.02.04.1-0.40.4-2.00.8-2.00.10.7-1.60.6-1.9-2.0-1.91.6
Body weight0.93.66.00.21.2-2.41.6-2.40.81.6-2.31.3-2.2-2.4-2.32.4
Epididymis fat weight0.10.20.4-0.5-0.60.2-0.60.3-0.6-0.60.5-0.60.30.30.3-0.5
Glucose1.31.93.20.10.8-1.71.1-1.80.61.1-1.71.0-1.7-1.8-1.71.8
Heart weight0.10.10.3-0.5-0.5-0.3-0.4-0.1-0.5-0.4-0.1-0.4-0.3-0.1-0.3-0.1
Left kidney weight0.51.43.11.71.70.31.60.31.81.6-0.91.70.20.30.30.9
Right kidney weight0.20.51.20.70.31.00.11.10.50.10.40.21.01.11.0-0.6
Tail length3.410.416.9-1.4-2.73.3-3.33.3-2.3-3.24.1-2.93.43.33.4-4.1
Length with tail1.13.96.4-0.1-1.02.5-1.52.4-0.7-1.42.5-1.22.52.42.5-2.4
Length without tail0.40.81.61.21.20.11.20.01.31.2-0.71.20.00.00.00.8
Liver weight, left1.01.63.5-0.50.2-1.90.5-1.7-0.00.5-1.50.3-1.8-1.7-1.91.4
Liver weight, right0.71.21.80.30.8-1.31.0-1.30.61.0-1.30.9-1.2-1.3-1.21.2
Parametrial fat weight0.10.20.3-0.5-0.50.1-0.50.0-0.5-0.50.4-0.50.10.00.1-0.5
Retroperitoneal fat weight1.65.39.5-0.20.9-3.11.5-3.00.51.4-2.81.2-3.1-3.0-3.12.8
Intraocular pressure1.01.42.7-1.5-1.60.3-1.60.3-1.6-1.61.2-1.60.20.30.2-1.0
Extensor digitorum longus weight3.514.027.4-1.01.0-5.22.0-5.10.31.9-4.31.4-5.1-5.1-5.14.4
Soleus weight4.212.420.60.42.2-4.42.9-4.41.52.9-4.32.4-4.2-4.4-4.24.5
Tibialis anterior weight0.93.05.00.31.1-2.11.4-2.10.81.4-2.11.2-2.1-2.1-2.12.2
Tibia length0.82.23.9-0.6-1.21.5-1.51.5-1.0-1.42.0-1.41.71.51.5-1.9
Number of licking bursts2.12.55.3-0.80.1-2.30.5-2.2-0.30.5-1.70.2-2.2-2.2-2.21.8
Food consumed during 24 hour testing period0.30.40.70.20.4-0.80.5-0.80.30.5-0.70.5-0.6-0.8-0.60.7
Times rat made contact with spout0.70.82.2-0.6-0.1-1.50.2-1.2-0.30.1-0.90.0-1.3-1.2-1.30.9
Mean time between licks in bursts0.91.21.8-0.8-1.20.8-1.31.1-1.1-1.31.1-1.30.81.10.8-1.3
Mean num. licks in bursts0.40.51.10.3-0.11.0-0.31.00.0-0.30.9-0.21.01.01.0-0.9
Std. dev. time between licks in bursts0.60.71.31.10.71.10.51.00.90.50.30.61.11.01.1-0.5
Water consumed over 24 hours1.31.52.71.41.6-0.61.6-0.71.51.6-1.31.6-0.5-0.7-0.51.2
Indifference point 0 sec2.74.47.60.81.6-2.32.1-2.21.42.0-2.81.9-2.4-2.2-2.42.6
Indifference point AUC0.50.60.9-0.2-0.50.8-0.71.0-0.5-0.60.9-0.70.91.00.9-0.8
Indifference point function ln k0.10.20.4-0.00.1-0.50.3-0.60.10.2-0.60.2-0.6-0.6-0.60.3
Indifference point function log k0.10.20.4-0.00.1-0.50.3-0.60.10.2-0.60.2-0.6-0.6-0.60.3
Delay discounting total patch changes 0 sec2.44.06.90.61.4-2.31.9-2.21.21.8-2.61.7-2.3-2.2-2.32.4
Delay discounting total patch changes 12 sec1.11.53.3-0.60.1-1.80.4-1.7-0.20.4-1.40.2-1.7-1.7-1.71.3
Delay discounting total patch changes 18 sec0.00.00.00.00.1-0.20.1-0.10.10.1-0.10.1-0.2-0.1-0.20.2
Delay discounting total patch changes 24 sec0.50.61.00.60.8-0.70.9-0.60.70.9-0.90.9-0.6-0.6-0.61.0
Delay discounting total patch changes 6 sec1.32.13.60.41.0-1.81.3-1.60.81.2-1.91.1-1.7-1.6-1.71.7
Delay discounting time to switch 0 sec0.40.61.20.91.1-0.21.1-0.31.01.1-0.71.0-0.3-0.3-0.30.9
Delay discounting water rate 0 sec0.50.81.5-1.0-0.6-1.2-0.3-1.2-0.7-0.4-0.7-0.4-1.2-1.2-1.20.5
Delay discounting water rate 12 sec0.71.12.3-1.1-0.6-1.5-0.2-1.5-0.7-0.3-0.8-0.3-1.4-1.5-1.40.6
Delay discounting water rate 18 sec1.82.45.7-2.4-2.2-0.9-1.9-0.9-2.3-1.90.5-2.0-0.9-0.9-0.9-0.7
Delay discounting water rate 24 sec2.63.67.0-2.6-1.9-2.2-1.3-2.3-2.2-1.4-0.5-1.6-2.1-2.3-2.10.4
Delay discounting water rate 6 sec1.31.83.9-1.8-2.0-0.0-1.80.1-1.9-1.90.9-1.8-0.00.1-0.0-1.3
Locomotor activity2.03.26.50.8-0.22.5-0.72.50.2-0.62.1-0.42.52.52.5-2.0
Locomotor testing distance0.71.22.40.5-0.11.5-0.41.60.1-0.41.3-0.21.51.61.5-1.3
Locomotor testing rearing0.10.10.2-0.5-0.4-0.2-0.4-0.3-0.5-0.40.3-0.4-0.2-0.3-0.2-0.1
Light reinforcement 12.24.07.1-0.0-1.12.6-1.52.5-0.6-1.52.4-1.12.52.52.5-2.7
Light reinforcement 20.60.81.5-0.1-0.51.2-0.71.1-0.4-0.71.1-0.61.01.11.0-1.2
Reaction time number correct0.71.12.4-1.0-0.4-1.4-0.1-1.6-0.6-0.1-0.7-0.3-1.4-1.6-1.40.9
Reaction time mean minus median0.91.22.40.1-0.51.5-0.71.5-0.3-0.71.3-0.61.51.51.5-1.3
Reaction time mean minus median AUC1.62.14.21.50.82.10.42.01.10.50.90.62.02.02.0-0.8
Reaction time num false alarms0.40.61.2-0.30.1-1.00.3-1.1-0.00.3-0.80.2-1.1-1.1-1.10.8
Reaction time num false alarms AUC0.60.81.7-0.6-0.2-1.20.1-1.3-0.30.1-0.8-0.0-1.3-1.3-1.30.8
Reaction time trials correct on left0.71.12.4-1.0-0.4-1.4-0.1-1.6-0.6-0.1-0.7-0.3-1.4-1.6-1.40.9
Reaction time trials on left0.71.02.2-0.9-0.3-1.4-0.1-1.5-0.6-0.0-0.7-0.2-1.3-1.5-1.30.9
Reaction time mean1.11.43.60.90.41.7-0.01.90.60.11.00.11.71.91.7-0.9
Reaction time mean AUC0.60.92.11.00.61.20.31.40.70.30.50.41.21.41.2-0.4
Median of all reaction times0.70.92.30.90.51.20.21.50.70.30.70.31.21.51.2-0.5
Reaction time omissions0.10.10.20.50.40.10.40.30.50.4-0.20.40.10.30.10.1
Reaction time false alarm rate0.10.10.20.20.4-0.40.4-0.30.30.4-0.50.4-0.4-0.3-0.40.5
Reaction time premature initiation rate1.52.13.4-1.4-1.70.8-1.80.7-1.6-1.81.8-1.80.90.70.9-1.8
Reaction time premature initiations1.52.14.2-2.0-2.00.1-2.0-0.1-2.0-1.91.4-2.00.1-0.10.1-1.3
Std. dev. reaction times0.70.92.10.60.21.4-0.11.40.3-0.10.90.01.41.41.4-0.8
Reaction time trials completed0.71.02.2-0.9-0.3-1.4-0.1-1.5-0.6-0.0-0.7-0.2-1.3-1.5-1.30.9
Reaction time trials AUC0.91.22.7-1.1-0.5-1.5-0.2-1.6-0.8-0.2-0.7-0.4-1.5-1.6-1.50.9
Social response proportion0.70.71.80.50.11.2-0.11.10.3-0.01.0-0.01.31.11.3-0.7
Social responses5.77.414.60.6-0.73.8-1.53.6-0.3-1.43.3-1.13.83.63.8-3.2
Social time0.81.01.9-0.20.3-1.40.6-1.30.10.6-1.10.4-1.4-1.3-1.41.3
Conditioned locomotion1.11.32.8-1.3-0.7-1.4-0.5-1.7-1.0-0.4-0.5-0.7-1.4-1.7-1.40.7
Cocaine response after cond. corrected1.71.93.9-1.3-0.5-2.0-0.1-1.9-0.8-0.1-1.2-0.4-2.0-1.9-2.01.2
Cocaine response after cond. not corrected1.92.14.4-1.4-0.7-2.1-0.2-2.0-1.0-0.3-1.2-0.5-2.0-2.0-2.01.1
Cocaine response before conditioning0.30.30.70.3-0.10.8-0.20.70.1-0.20.7-0.10.90.70.9-0.7
Saline control response0.30.30.9-0.30.0-0.80.2-1.0-0.10.2-0.60.1-0.7-1.0-0.70.7
Condit. Reinf. active minus inactive responses2.02.54.1-1.3-1.81.1-2.01.0-1.7-2.01.8-1.91.01.01.0-2.0
Condit. Reinf. active-inactive response ratio1.91.93.9-1.9-2.0-0.0-1.90.0-2.0-1.91.2-1.9-0.00.0-0.0-1.3
Condit. Reinf. active responses1.01.32.7-0.4-1.01.2-1.21.2-0.8-1.21.4-1.01.21.21.2-1.6
Condit. Reinf. inactive responses0.30.40.90.70.30.90.20.80.50.10.30.30.90.80.9-0.5
Condit. Reinf. lever presses2.33.15.4-1.2-1.81.6-2.01.4-1.6-2.02.2-1.91.61.41.6-2.3
Condit. Reinf. lever reinforcers received0.81.22.3-0.7-1.21.0-1.30.9-1.0-1.31.3-1.20.90.90.9-1.5
Pavlov. Cond. lever latency1.11.42.50.10.7-1.61.0-1.40.50.9-1.50.8-1.5-1.4-1.51.5
Pavlov. Cond. magazine entry latency1.61.83.20.0-0.71.7-1.01.8-0.4-1.01.6-0.81.71.81.7-1.7
Pavlov. Cond. change in total contacts0.50.71.4-0.3-0.70.9-0.80.9-0.6-0.91.0-0.70.80.90.8-1.2
Pavlov. Cond. index score1.41.93.2-0.3-0.91.6-1.21.7-0.7-1.21.7-1.01.51.71.5-1.8
Pavlov. Cond. latency score1.41.83.0-0.0-0.71.7-1.01.7-0.5-1.01.7-0.81.71.71.7-1.7
Pavlov. Cond. lever contacts1.01.42.4-0.6-1.01.3-1.21.2-0.9-1.21.5-1.11.21.21.2-1.5
Pavlov. Cond. magazine entry number1.41.73.1-0.00.6-1.70.9-1.80.40.9-1.50.7-1.6-1.8-1.61.7
Pavlov. Cond. intertrial magazine entries0.70.92.1-0.6-0.1-1.30.2-1.4-0.30.1-0.90.0-1.3-1.4-1.30.9
Pavlov. Cond. lever-magazine prob. diff.1.41.93.2-0.2-0.81.7-1.11.8-0.6-1.11.6-0.91.61.81.6-1.8
Pavlov. Cond. response bias1.62.23.8-0.7-1.31.6-1.51.6-1.1-1.51.8-1.41.51.61.5-1.9
Conditioned reinforcement - actives0.20.20.50.70.50.20.50.30.70.4-0.30.60.30.30.3-0.1
Conditioned reinforcement - inactives1.21.32.7-1.1-0.6-1.6-0.2-1.7-0.7-0.4-1.0-0.4-1.7-1.7-1.70.5
Conditioned locomotion1.51.84.50.0-0.81.6-1.01.6-0.4-1.11.5-0.81.61.61.6-2.1
Intermittent access intake day 1-15 change0.40.40.9-0.6-0.80.2-0.80.2-0.7-0.90.4-0.70.20.20.2-1.0
Intermittent access intake escalation1.31.32.8-1.6-1.7-0.4-1.4-0.4-1.6-1.60.5-1.4-0.4-0.4-0.4-1.0
Intermittent access intake escalation 21.41.42.9-1.5-1.70.1-1.60.1-1.6-1.71.0-1.50.10.10.1-1.4
Intermitt. access day 1 inactive lever presses1.11.22.4-1.5-1.5-0.5-1.3-0.5-1.5-1.40.5-1.4-0.5-0.5-0.5-0.9
Intermitt. access day 15 inactive lever presses1.21.32.5-1.3-1.60.4-1.50.4-1.4-1.61.2-1.40.40.40.4-1.5
Intermitt. access escalation Index0.80.71.71.31.10.60.90.61.20.9-0.41.10.60.60.60.1
Intermittent access day 1 total infusions0.30.40.60.50.7-0.50.7-0.50.60.7-0.80.7-0.5-0.5-0.50.8
Intermittent access day 15 total infusions0.20.20.4-0.4-0.3-0.6-0.1-0.6-0.3-0.2-0.4-0.1-0.6-0.6-0.60.1
Intermittent access terminal intake (last 3 days)0.20.20.60.50.5-0.30.6-0.40.60.5-0.80.6-0.3-0.4-0.30.4
Intermittent access total infusions0.30.30.60.00.2-0.70.4-0.70.20.3-0.80.3-0.7-0.7-0.70.5
Intermittent access day 1 locomotion0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.1-0.1-0.1-0.0
Intermittent access day 15 total locomotion0.40.41.2-0.5-0.80.3-0.80.3-0.7-0.90.5-0.70.30.30.3-1.1
Intermittent access total locomotion0.10.20.40.0-0.20.5-0.30.5-0.1-0.30.4-0.20.50.50.5-0.6
Intermittent access standard deviation0.30.30.7-0.7-0.80.0-0.7-0.0-0.7-0.90.3-0.7-0.0-0.0-0.0-0.8
Cocaine induced anxiety1.31.53.11.10.51.80.11.80.70.21.10.31.81.81.8-0.9
Post-drug Anxiety1.41.63.51.91.51.21.21.21.61.20.11.31.21.21.20.1
Baseline Anxiety0.10.10.2-0.5-0.4-0.2-0.3-0.2-0.4-0.3-0.0-0.3-0.2-0.2-0.2-0.1
Lifetime Intake0.80.92.00.50.9-1.01.1-0.90.81.0-1.41.0-0.9-0.9-0.91.1
Incentive Sensitization - Responses0.10.10.2-0.0-0.20.2-0.20.3-0.1-0.20.2-0.10.30.30.3-0.4
Incentive Sensitization - Breakpoint0.10.10.20.2-0.00.4-0.10.40.1-0.10.20.00.40.40.4-0.5
Progressive ratio test 1 active lever presses1.01.01.8-0.00.4-1.30.7-1.30.30.6-1.30.6-1.3-1.3-1.31.1
Progressive ratio test 1 breakpoint1.01.12.00.10.6-1.30.8-1.30.50.8-1.40.7-1.3-1.3-1.31.2
Progressive ratio test 1 inactive lever presses0.00.00.10.1-0.0-0.10.1-0.10.1-0.1-0.40.1-0.1-0.1-0.1-0.3
Progressive ratio test 2 active lever presses0.40.40.90.20.4-0.80.6-0.70.40.5-1.00.5-0.7-0.7-0.70.6
Progressive ratio test 2 breakpoint0.30.30.60.70.7-0.20.8-0.20.80.7-0.80.8-0.2-0.2-0.20.4
Progressive ratio test 2 inactive lever presses0.30.30.80.60.6-0.40.7-0.40.70.6-0.90.8-0.4-0.4-0.40.5
Total sessions with >9 infusions1.11.32.71.61.5-0.01.50.01.61.4-1.31.60.00.00.00.7
Short access day 1 total inactive lever presses0.00.00.10.10.1-0.10.1-0.10.10.0-0.30.2-0.1-0.1-0.1-0.1
Short access day 10 total inactive lever presses0.50.61.2-1.1-1.1-0.5-0.8-0.5-1.0-1.00.1-0.9-0.5-0.5-0.5-0.6
Short access day 1 total infusions1.81.93.81.71.8-0.41.9-0.41.91.7-1.81.9-0.4-0.4-0.41.2
Short access day 10 total infusions0.60.71.40.40.6-0.90.8-0.90.60.7-1.20.7-0.9-0.9-0.90.8
Short access total infusions2.02.34.21.41.7-0.91.9-0.91.71.8-2.01.9-0.9-0.9-0.91.6
Short access day 1 locomotion0.20.20.50.70.50.30.40.40.60.4-0.20.50.40.40.4-0.2
Short access day 10 total locomotion1.61.73.9-1.1-1.60.8-1.60.8-1.3-1.71.4-1.50.80.80.8-2.0
Short access total locomotion0.10.10.30.2-0.00.4-0.10.40.1-0.10.2-0.00.40.40.4-0.5
Compulsive drug intake0.20.20.40.30.5-0.30.5-0.30.40.5-0.50.5-0.3-0.3-0.30.6
One hour access (0.3 mA shock)0.30.30.60.10.3-0.70.5-0.60.30.4-0.80.5-0.6-0.6-0.60.7
One hour access (shock baseline)0.30.30.5-0.7-0.6-0.7-0.4-0.6-0.6-0.5-0.2-0.5-0.6-0.6-0.6-0.1
Number of responses in last shaping day0.60.61.7-0.2-0.60.8-0.70.8-0.4-0.80.8-0.60.80.80.8-1.3
Context. condit. distance diff. score0.10.20.3-0.10.1-0.50.2-0.50.00.2-0.50.2-0.6-0.5-0.60.5
Locomotion velocity, session 11.01.12.41.51.50.31.40.21.51.4-0.51.40.40.20.40.7
Locomotion distance, session 11.01.33.11.81.41.01.21.01.61.2-0.11.31.01.01.00.1
Locomotion velocity, session 21.61.93.31.81.21.70.81.81.40.80.51.01.71.81.7-0.7
Locomotion distance, session 22.23.26.51.70.82.60.32.51.20.41.40.62.52.52.5-1.3
Locomotion velocity, session 33.33.96.3-0.4-1.32.4-1.72.3-1.0-1.72.5-1.52.32.32.3-2.5
Locomotion distance, session 30.10.10.2-0.3-0.40.2-0.40.2-0.4-0.40.4-0.40.20.20.2-0.3
Stereotopy head waving bouts, day 33.64.37.70.2-0.92.8-1.32.7-0.4-1.32.5-1.02.72.72.7-2.6
Stereotopy head waving duration, day 32.32.85.10.1-0.82.2-1.12.2-0.4-1.21.9-0.92.12.22.1-2.3
Locomotion velocity, session 70.10.20.30.50.40.40.30.50.40.30.10.30.40.50.4-0.1
Locomotion distance, session 70.20.30.7-0.9-0.7-0.5-0.5-0.4-0.8-0.6-0.1-0.6-0.6-0.4-0.60.0
Stereotopy head waving bouts, day 70.91.02.01.20.81.40.41.20.90.50.70.61.41.21.4-0.6
Stereotopy head waving duration, day 71.01.22.31.51.11.40.71.21.20.80.60.91.41.21.4-0.4
Locomotion velocity, session 81.72.03.31.81.21.80.81.81.40.90.81.01.81.81.8-0.5
Locomotion distance, session 80.30.41.10.50.21.00.01.00.40.10.60.10.91.00.9-0.4
Degree of sensitization distance0.40.40.70.20.5-0.70.6-0.70.40.6-0.80.5-0.7-0.7-0.70.8
Degree of sensitization stereotypy0.60.61.31.11.20.21.00.01.11.1-0.41.10.20.00.20.7
Condit. Reinf. active minus inactive responses1.31.52.90.0-0.61.5-0.91.7-0.4-0.91.4-0.71.41.71.4-1.5
Condit. Reinf. active-inactive response ratio0.40.40.8-0.7-0.80.2-0.80.4-0.7-0.90.6-0.80.20.40.2-0.8
Condit. Reinf. active responses1.92.35.50.8-0.12.2-0.52.30.3-0.51.5-0.22.12.32.1-1.6
Condit. Reinf. inactive responses1.31.63.31.20.61.80.21.80.80.31.00.41.71.81.7-0.9
Incentive salience index mean1.01.22.90.80.21.6-0.11.70.5-0.10.90.11.51.71.5-1.0
Condit. Reinf. lever presses1.31.84.02.01.61.31.31.31.81.40.01.51.21.31.20.2
Time in familiar zone, hab. session 13.93.76.2-0.9-1.72.0-2.01.9-1.4-2.02.5-1.82.01.92.0-2.4
Time in novel zone, hab. session 13.83.75.71.72.2-1.42.4-1.32.02.3-2.32.3-1.4-1.3-1.42.2
Total zone transitions, hab. session 10.81.22.21.51.01.30.71.31.20.80.40.91.31.31.3-0.3
Total locomotion distance, hab. session 12.13.05.32.21.42.30.92.31.70.90.91.22.22.32.2-0.8
Locomotion velocity, hab. session 11.72.55.11.70.92.20.42.21.20.51.10.72.12.22.1-1.1
Time in familiar zone, hab. session 24.34.47.0-1.4-2.21.8-2.41.9-1.9-2.42.6-2.31.81.91.8-2.6
Time in novel zone, hab. session 25.05.07.61.72.4-1.82.7-1.82.22.6-2.72.5-1.8-1.8-1.82.8
Total zone transitions, hab. session 21.72.24.52.12.10.02.0-0.02.12.1-1.22.10.0-0.00.01.3
Total locomotion distance, hab. session 20.70.91.81.31.01.10.71.11.10.80.30.91.11.11.1-0.1
Locomotion velocity, hab. session 21.01.42.81.71.31.31.01.31.41.00.31.11.21.31.2-0.1
Novel to familiar place preference ratio3.33.55.71.82.3-1.12.4-1.22.12.4-2.12.3-1.1-1.2-1.12.1
Novelty place preference2.42.54.31.62.0-0.82.1-0.81.92.1-1.72.0-0.8-0.8-0.81.8
Time in novel zone, NPP test2.72.94.71.62.0-1.12.2-1.11.92.1-2.02.1-1.1-1.1-1.12.0
Total zone transitions, NPP test0.60.91.71.21.3-0.11.3-0.21.21.3-0.81.3-0.1-0.2-0.11.0
Total locomotion distance, NPP test0.71.02.11.51.40.41.20.41.41.3-0.51.30.40.40.40.7
Locomotion velocity, NPP test0.60.81.81.31.20.71.00.71.21.0-0.11.10.70.70.70.3
Pavlov. Cond. lever latency0.60.81.8-1.3-1.1-0.8-0.9-0.9-1.2-1.00.1-1.0-0.7-0.9-0.7-0.2
Pavlov. Cond. magazine entry latency1.21.62.4-0.5-1.01.3-1.21.6-0.8-1.21.5-1.11.31.61.3-1.5
Pavlov. Cond. change in total contacts0.10.10.30.30.4-0.30.4-0.00.40.4-0.60.4-0.4-0.0-0.40.5
Pavlov. Cond. index score0.50.61.60.80.41.10.21.30.50.20.50.31.01.31.0-0.4
Pavlov. Cond. latency score0.70.92.01.10.71.20.51.40.90.50.40.61.11.41.1-0.4
Pavlov. Cond. lever contacts1.01.22.71.71.50.71.20.91.51.3-0.31.30.70.90.70.5
Pavlov. Cond. magazine entry number0.40.51.20.10.4-0.90.5-1.10.30.5-0.80.5-0.8-1.1-0.80.8
Pavlov. Cond. intertrial magazine entries0.40.51.1-1.0-1.0-0.1-0.9-0.2-1.0-1.00.4-1.0-0.2-0.2-0.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.80.70.31.10.01.40.40.10.60.21.11.41.1-0.6
Pavlov. Cond. response bias0.50.71.60.1-0.31.1-0.51.3-0.2-0.50.9-0.41.01.31.0-0.8
Bone: apparent density1.93.27.52.72.40.92.20.92.62.2-0.82.40.90.90.90.8
Bone surface3.56.215.03.93.21.72.81.73.62.8-0.93.11.71.71.70.6
Bone volume3.86.415.53.93.41.53.01.63.73.0-1.13.31.51.61.50.9
Bone: connectivity density1.11.74.12.01.80.71.60.71.91.6-0.61.70.70.70.70.5
Bone: cortical apparent density0.91.22.30.10.6-1.40.9-1.20.40.8-1.50.7-1.4-1.2-1.41.4
Bone: cortical area1.62.54.51.92.1-0.52.1-0.52.12.1-1.82.1-0.5-0.5-0.51.6
Bone: cortical porosity0.20.20.50.70.50.30.50.50.60.4-0.20.60.20.50.2-0.0
Bone: cortical porosity0.60.71.41.21.10.01.10.21.21.0-0.81.2-0.10.2-0.10.5
Bone: cortical thickness1.32.23.71.11.5-1.21.7-1.31.41.7-1.91.6-1.2-1.3-1.21.8
Bone: cortical thickness0.60.71.5-0.40.0-1.20.3-1.2-0.10.2-0.90.1-1.2-1.2-1.20.9
Bone: cortical tissue density0.60.81.60.00.5-1.20.7-1.00.30.6-1.30.6-1.2-1.0-1.21.2
Bone: elastic displacement0.00.00.10.20.20.10.20.10.20.2-0.10.20.10.10.1-0.0
Bone: elastic work0.71.01.60.91.2-0.61.3-0.61.11.3-1.11.2-0.6-0.6-0.61.2
Bone: endosteal estimation0.71.42.51.11.4-0.81.5-0.71.31.5-1.61.5-0.7-0.7-0.71.3
Bone: endosteal perimeter0.40.81.61.30.80.90.71.11.10.60.10.80.91.10.9-0.3
Bone: final force2.74.56.81.82.4-1.52.6-1.62.22.6-2.52.5-1.5-1.6-1.52.5
Bone: final moment2.64.36.61.82.4-1.52.6-1.62.22.5-2.52.5-1.5-1.6-1.52.5
Bone: marrow area0.61.32.21.11.3-0.81.4-0.71.31.4-1.51.4-0.7-0.7-0.71.3
Bone: maximum diameter0.71.32.81.71.21.21.01.21.50.9-0.01.21.21.21.2-0.2
Bone: maximum force2.74.77.01.62.3-1.72.6-1.82.12.5-2.72.4-1.7-1.8-1.72.6
Bone: maximum moment2.64.66.91.62.3-1.72.6-1.82.12.5-2.62.4-1.7-1.8-1.72.6
Bone: minimum diameter0.61.12.11.41.4-0.21.40.01.51.3-1.11.4-0.20.0-0.20.9
Bone: periosteal estimation1.63.25.82.02.3-0.72.4-0.62.32.3-2.12.4-0.7-0.6-0.71.8
Bone: periosteal perimeter0.81.33.11.81.60.41.50.61.71.4-0.71.60.40.60.40.5
Bone: post-yield work0.30.40.70.10.4-0.80.6-0.80.30.5-0.80.5-0.8-0.8-0.80.7
Bone: stiffness3.75.89.41.32.2-2.32.6-2.51.92.5-3.12.4-2.3-2.5-2.33.0
Bone: tissue strength3.33.25.30.81.5-1.91.8-1.91.31.8-2.31.7-1.9-1.9-1.92.2
Bone: trabecular number1.01.63.01.71.21.60.81.51.40.90.51.11.61.51.6-0.5
Bone: trabecular spacing2.33.07.0-2.6-2.2-1.4-1.9-1.3-2.4-1.90.3-2.1-1.4-1.3-1.4-0.4
Bone: trabecular thickness4.85.913.63.73.41.13.01.13.63.0-1.33.31.11.11.11.2
Bone: trabecular tissue density3.85.310.5-0.60.6-3.21.2-3.20.11.1-2.70.8-3.1-3.2-3.12.6
Breakpoint value in progressive ratio session1.71.93.3-0.8-1.41.3-1.51.4-1.1-1.51.7-1.31.31.41.3-1.8
Distance traveled before self-admin0.70.71.50.2-0.31.1-0.51.2-0.1-0.41.0-0.31.11.21.1-1.0
Distance traveled after self-admin0.10.10.30.30.10.5-0.00.50.2-0.00.40.00.60.50.6-0.4
Delta time in closed arm before/after self-admin2.42.34.8-2.2-1.7-1.7-1.3-1.5-1.9-1.3-0.3-1.5-1.7-1.5-1.70.1
Delta time in open arm before/after self-admin1.21.12.30.71.1-0.81.2-1.10.91.3-1.21.1-0.8-1.1-0.81.5
Diff in mean of infusions in LGA sessions1.51.73.2-0.5-1.11.4-1.31.4-0.8-1.31.6-1.11.41.41.4-1.8
Extinction: sum of active levers before priming3.23.25.0-1.5-2.01.2-2.21.3-1.9-2.22.2-2.21.21.31.2-2.1
Active lever presses in extinction session 60.90.82.00.3-0.21.3-0.41.4-0.0-0.41.1-0.31.21.41.2-0.9
Delta distance traveled before/after self-admin0.00.10.10.30.3-0.10.3-0.20.30.3-0.30.2-0.1-0.2-0.10.2
Delta ambulatory time before/after self-admin0.20.30.60.80.80.00.70.00.80.7-0.40.70.00.00.00.4
Time in closed arm before self-admin0.91.02.11.41.40.21.30.11.51.4-0.71.40.20.10.20.8
Time in closed arm after self-admin0.20.20.50.10.2-0.60.4-0.50.20.3-0.70.4-0.5-0.5-0.50.4
Time in open arm before self-admin0.50.51.1-0.8-1.00.1-1.00.4-0.9-1.10.5-0.90.10.40.1-1.0
Time in open arm after self-admin0.70.81.8-0.30.1-1.20.4-1.3-0.10.4-0.90.2-1.2-1.3-1.21.0
Sum of active levers in priming session hrs 5-60.30.30.4-0.3-0.50.5-0.50.5-0.4-0.50.6-0.50.50.50.5-0.6
Time to tail flick, vehicle, before self-admin1.71.73.11.60.91.80.61.71.20.50.60.91.81.71.8-0.9
Time to tail flick, vehicle, after self-admin0.70.71.4-1.1-1.20.1-1.20.1-1.2-1.10.8-1.20.10.10.1-0.8
Time to tail flick, test, before self-admin1.11.02.01.20.71.40.41.40.90.40.50.61.31.41.3-0.6
Time to tail flick, test, after self-admin0.60.61.41.21.00.70.80.71.10.8-0.10.90.70.70.70.1
Delta time to tail flick, vehicle, before/after SA1.51.42.7-1.6-1.0-1.4-0.8-1.4-1.4-0.7-0.2-1.0-1.5-1.4-1.50.7
Delta time to tail flick, test, before/after SA0.40.30.7-0.8-0.8-0.0-0.8-0.1-0.9-0.80.6-0.8-0.0-0.1-0.0-0.4
Ambulatory time before self-admin0.20.20.40.0-0.20.5-0.30.6-0.1-0.30.5-0.20.60.60.6-0.6
Ambulatory time after self-admin0.00.00.10.30.20.20.10.20.20.10.10.10.30.20.3-0.2
Total heroin consumption1.61.93.50.3-0.41.9-0.81.9-0.2-0.71.7-0.61.91.91.9-1.6
Area under the delay curve0.20.20.40.60.60.10.50.10.60.6-0.20.50.10.10.10.4
Delay disc. indifference point, 0s delay2.72.95.72.12.4-0.42.3-0.32.32.4-1.62.3-0.4-0.3-0.41.9
Delay disc. indifference point, 16s delay0.10.10.30.1-0.00.6-0.20.40.0-0.10.5-0.10.60.40.6-0.3
Delay disc. indifference point, 2s delay0.60.61.21.01.1-0.11.00.11.11.1-0.61.1-0.10.1-0.10.9
Delay disc. indifference point, 24s delay0.20.20.60.30.6-0.40.6-0.40.40.6-0.40.5-0.3-0.4-0.30.8
Delay disc. indifference point, 4s delay0.60.71.11.10.70.90.51.10.90.60.30.61.01.11.0-0.2
Delay disc. indifference point, 8s delay0.20.20.4-0.6-0.4-0.5-0.3-0.4-0.5-0.3-0.0-0.4-0.5-0.4-0.50.2
Delay discount exponential model param0.10.10.2-0.5-0.5-0.1-0.4-0.2-0.5-0.50.1-0.4-0.2-0.2-0.2-0.3
Delay discount hyperbolic model param0.20.20.5-0.6-0.70.0-0.6-0.1-0.6-0.70.3-0.6-0.0-0.1-0.0-0.5
Fecal boli incidents, locomotor time 10.70.81.7-1.0-0.5-1.1-0.3-1.3-0.8-0.3-0.4-0.5-1.1-1.3-1.10.6
Change in fecal boli incidents, locomotor task1.00.91.81.30.91.10.71.21.10.70.30.81.11.21.1-0.3
Time >=10cm from walls, locomotor time 11.11.12.01.21.4-0.31.4-0.41.41.4-1.11.4-0.3-0.4-0.31.0
Bouts of movement, locomotor time 10.30.40.7-0.4-0.60.6-0.70.5-0.5-0.70.7-0.60.60.50.6-0.9
Total resting periods, locomotor time 10.70.81.4-0.2-0.61.1-0.81.0-0.5-0.81.1-0.71.11.01.1-1.2
Rest time, locomotor task time 10.30.30.90.30.00.9-0.10.80.1-0.10.6-0.00.90.80.9-0.6
Distance moved, locomotor task time 11.11.22.11.31.4-0.51.5-0.41.41.4-1.11.4-0.4-0.4-0.41.1
Vertical activity count, locomotor time 10.80.81.9-0.20.2-1.40.5-1.10.10.4-1.20.4-1.3-1.1-1.31.0
Time >=10cm from walls, locomotor time 20.80.81.8-0.40.0-1.30.3-1.3-0.10.2-1.00.1-1.3-1.3-1.30.9
Bouts of movement, locomotor time 20.50.51.11.10.70.90.60.70.90.60.20.70.90.70.9-0.3
Total resting periods, locomotor time 20.60.71.51.20.90.90.70.71.10.70.10.90.90.70.9-0.2
Rest time, locomotor task time 20.30.40.91.00.80.60.70.30.90.7-0.00.70.50.30.50.1
Distance moved, locomotor task time 20.30.40.9-1.0-0.8-0.6-0.6-0.5-0.9-0.70.0-0.7-0.5-0.5-0.5-0.1
Vertical activity count, locomotor time 21.31.43.1-1.2-0.6-1.8-0.3-1.5-0.8-0.3-0.9-0.4-1.7-1.5-1.70.9
Weight adjusted by age0.20.30.6-0.8-0.7-0.3-0.6-0.4-0.7-0.60.2-0.6-0.3-0.4-0.3-0.2
Seeking ratio, delayed vs. immediate footshock0.80.91.90.70.01.4-0.21.40.3-0.20.80.01.41.41.4-1.2
Locomotion in novel chamber0.20.20.4-0.00.1-0.60.3-0.70.10.2-0.60.2-0.6-0.7-0.60.4
Locomotion in novel chamber post-restriction2.42.84.6-0.3-1.12.1-1.42.0-0.8-1.42.1-1.22.12.02.1-2.1
Progressive ratio0.81.02.0-0.30.2-1.40.5-1.40.00.4-1.20.3-1.4-1.4-1.41.0
Food seeking constrained by brief footshock1.21.52.7-0.3-0.81.5-1.11.5-0.6-1.01.7-0.91.51.51.5-1.3
Seeking ratio, punishment vs. effort1.72.13.7-0.2-0.81.8-1.11.8-0.6-1.01.9-1.01.81.81.8-1.6
Run reversals in cocaine runway, females1.31.32.80.5-0.11.5-0.41.70.1-0.41.3-0.31.61.71.6-1.3
Run reversals in cocaine runway, males1.61.63.20.5-0.21.8-0.51.80.1-0.51.3-0.31.81.81.8-1.4
Latency to leave start box in cocaine runway1.31.43.01.71.70.41.50.31.71.6-0.81.60.40.30.41.0
Latency to leave start box in cocaine runway, F2.52.85.92.42.40.52.10.52.42.2-1.02.30.60.50.61.3
Latency to leave start box in cocaine runway, M0.50.51.0-1.0-0.9-0.5-0.7-0.6-0.9-0.80.1-0.8-0.6-0.6-0.6-0.2
Cd content in liver0.20.20.50.20.4-0.50.5-0.20.30.5-0.60.3-0.5-0.2-0.50.7
Co content in liver1.21.42.0-0.9-1.30.9-1.41.0-1.2-1.41.3-1.40.81.00.8-1.4
Cu content in liver1.51.83.21.51.7-0.71.8-0.61.71.7-1.61.8-0.7-0.6-0.71.3
Fe content in liver0.40.41.0-0.5-0.2-1.0-0.0-0.9-0.3-0.0-0.6-0.1-1.0-0.9-1.00.6
K content in liver0.60.61.20.90.51.00.30.90.70.30.50.51.10.91.1-0.5
Mg content in liver0.80.91.71.30.91.00.71.11.10.70.30.81.11.11.1-0.2
Mn content in liver2.42.86.62.62.01.51.71.42.31.7-0.12.01.51.41.50.0
Na content in liver0.30.40.80.80.90.10.8-0.20.80.9-0.30.90.1-0.20.10.5
Rb content in liver1.11.32.51.41.5-0.51.6-0.21.61.5-1.31.6-0.4-0.2-0.41.0
Se content in liver0.10.10.20.20.10.30.10.40.20.10.20.10.30.40.3-0.1
Sr content in liver1.11.02.1-1.4-1.4-0.2-1.3-0.2-1.5-1.40.5-1.4-0.2-0.2-0.2-0.8
Zn content in liver3.13.46.1-2.1-2.40.7-2.50.7-2.4-2.41.9-2.50.70.70.7-1.9