Foxred1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000091308 0.5 0.2 2.4e-05 -0 0.03 0.03 0.01 7.6e-01 4.1e-04 1.8e-04 1.3e-02
2 Adipose isoform ratio ENSRNOT00000111624 0.44 0.2 4.2e-05 -0 0.03 0.03 0.01 8.3e-01 4.4e-04 3.1e-04 3.1e-02
3 BLA intron excision ratio chr8:33557855:33558117 0.04 0.05 9.6e-03 0.05 0.02 0.02 0.03 7.1e-04 1.8e-02 2.8e-02 1.6e-02
4 Brain intron excision ratio chr8:33554249:33554420 0.03 0.03 8.8e-04 0.01 0.03 0.02 0.02 4.3e-02 1.2e-03 1.1e-02 6.7e-03
5 Brain mRNA stability ENSRNOG00000060379 0.1 0.1 4.2e-07 0.04 0.07 0.06 0.05 9.7e-05 3.1e-07 8.1e-06 4.2e-05
6 Liver gene expression ENSRNOG00000060379 0.22 0.13 8.2e-03 -0 0.01 0.03 -0 5.9e-01 1.3e-02 2.6e-04 6.1e-01
7 Liver isoform ratio ENSRNOT00000091308 0.38 0.14 1.1e-05 -0 0.03 0.03 0.03 8.7e-01 1.5e-04 6.5e-04 1.5e-04
8 Liver isoform ratio ENSRNOT00000111624 0.38 0.14 5.5e-06 -0 0.04 0.04 0.04 8.6e-01 8.1e-05 7.3e-05 7.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.51.62.41.4-1.41.11.51.50.9-0.01.5
BMI without tail1.02.09.20.8-0.70.51.41.3-0.3-3.01.2
Body weight1.04.15.32.0-1.92.32.32.32.10.42.1
Epididymis fat weight1.12.64.11.4-1.42.01.71.71.80.31.8
Glucose0.00.10.1-0.40.4-0.0-0.4-0.30.0-0.1-0.0
Heart weight0.20.30.7-0.60.5-0.3-0.8-0.80.50.1-0.7
Left kidney weight0.72.04.41.4-1.41.41.41.52.10.80.9
Right kidney weight0.92.46.61.5-1.50.71.71.71.0-2.61.2
Tail length0.92.84.51.6-1.61.52.12.01.0-1.71.6
Length with tail0.62.13.31.2-1.21.81.61.51.8-0.31.6
Length without tail1.02.38.90.8-0.81.40.50.62.23.00.8
Liver weight, left1.11.75.81.2-1.21.01.11.22.40.70.9
Liver weight, right0.50.82.1-0.60.6-1.4-0.5-0.5-0.8-1.2-1.0
Parametrial fat weight1.42.87.41.3-1.21.12.01.9-0.5-2.71.8
Retroperitoneal fat weight0.92.94.21.8-1.72.02.12.00.70.81.9
Intraocular pressure0.10.10.3-0.40.4-0.1-0.3-0.4-0.60.3-0.3
Extensor digitorum longus weight1.14.510.5-1.91.8-2.3-2.4-2.4-0.31.4-3.2
Soleus weight1.95.610.2-2.22.2-1.9-2.7-2.7-0.92.3-3.2
Tibialis anterior weight1.03.68.2-1.81.8-1.9-2.1-2.1-0.21.3-2.9
Tibia length0.41.11.80.9-0.80.91.31.2-0.6-1.11.3
Number of licking bursts0.20.20.4-0.60.6-0.4-0.6-0.60.2-0.4-0.2
Food consumed during 24 hour testing period1.01.21.7-1.11.1-1.3-1.2-1.1-0.7-0.6-1.3
Times rat made contact with spout0.30.41.1-0.40.4-0.8-0.5-0.5-1.1-0.3-0.8
Mean time between licks in bursts0.10.10.40.3-0.20.30.40.40.2-0.70.5
Mean num. licks in bursts0.20.20.60.4-0.40.10.50.5-0.70.3-0.1
Std. dev. time between licks in bursts0.00.00.1-0.10.1-0.0-0.0-0.0-0.1-0.30.2
Water consumed over 24 hours2.12.53.4-1.71.6-1.6-1.8-1.8-1.3-0.2-1.8
Indifference point 0 sec1.32.14.71.1-1.01.61.61.50.7-1.42.2
Indifference point AUC0.81.02.11.0-1.00.71.11.2-0.0-0.91.4
Indifference point function ln k0.10.21.10.2-0.2-0.10.40.4-0.1-1.00.2
Indifference point function log k0.10.21.10.2-0.2-0.10.40.4-0.1-1.00.2
Delay discounting total patch changes 0 sec1.32.24.61.1-1.11.71.61.50.9-1.32.2
Delay discounting total patch changes 12 sec0.81.02.10.8-0.71.11.11.0-0.1-1.31.4
Delay discounting total patch changes 18 sec0.10.20.5-0.20.20.60.0-0.0-0.5-0.70.5
Delay discounting total patch changes 24 sec0.60.82.20.8-0.81.20.70.7-0.1-0.61.5
Delay discounting total patch changes 6 sec2.43.77.32.0-2.02.22.22.20.1-0.22.7
Delay discounting time to switch 0 sec2.23.35.3-1.91.9-1.6-2.1-2.1-1.10.9-2.3
Delay discounting water rate 0 sec1.82.96.71.5-1.41.81.71.80.8-1.52.6
Delay discounting water rate 12 sec2.23.25.82.4-2.40.81.92.02.01.20.8
Delay discounting water rate 18 sec0.50.71.80.8-0.90.40.70.71.4-0.40.9
Delay discounting water rate 24 sec0.91.21.90.9-0.91.31.11.01.4-0.51.4
Delay discounting water rate 6 sec1.01.42.21.5-1.51.21.31.31.2-0.01.0
Locomotor activity0.20.31.4-0.30.40.60.0-0.11.20.10.4
Locomotor testing distance0.10.20.5-0.70.7-0.1-0.3-0.40.1-0.2-0.2
Locomotor testing rearing0.50.71.0-1.01.0-0.8-0.7-0.8-1.0-0.8-0.7
Light reinforcement 10.40.84.10.5-0.5-0.10.80.70.1-2.00.6
Light reinforcement 20.50.63.20.4-0.4-0.80.50.5-0.5-1.80.1
Reaction time number correct0.30.40.70.7-0.70.50.60.60.90.20.5
Reaction time mean minus median1.41.93.7-1.31.2-1.1-1.7-1.7-0.81.0-1.9
Reaction time mean minus median AUC0.81.12.9-0.70.6-0.8-1.2-1.1-0.31.1-1.7
Reaction time num false alarms0.60.83.8-0.90.9-0.1-0.4-0.4-0.0-2.00.7
Reaction time num false alarms AUC0.91.37.4-0.80.80.1-0.1-0.10.1-2.71.3
Reaction time trials correct on left0.30.40.70.7-0.70.50.60.60.90.20.5
Reaction time trials on left0.30.40.70.7-0.70.50.60.60.80.20.5
Reaction time mean0.81.12.1-0.90.8-0.5-1.2-1.2-0.81.0-1.5
Reaction time mean AUC0.60.71.8-0.60.6-0.7-1.0-1.0-0.50.7-1.4
Median of all reaction times0.30.41.2-0.50.4-0.1-0.7-0.7-0.41.1-0.9
Reaction time omissions0.30.40.80.8-0.90.30.40.40.80.8-0.1
Reaction time false alarm rate0.81.14.9-1.11.2-0.3-0.5-0.6-0.3-2.20.7
Reaction time premature initiation rate1.01.35.70.4-0.40.60.30.32.42.00.1
Reaction time premature initiations1.01.46.00.7-0.70.70.60.62.41.80.4
Std. dev. reaction times1.92.75.1-1.51.5-1.5-1.9-1.9-1.30.9-2.3
Reaction time trials completed0.30.40.70.7-0.70.50.60.60.80.20.5
Reaction time trials AUC0.30.51.10.7-0.70.60.70.61.10.30.6
Social response proportion0.20.20.70.4-0.40.20.10.2-0.60.90.3
Social responses0.00.10.20.1-0.10.3-0.2-0.10.20.40.3
Social time1.01.34.60.8-0.81.30.70.72.11.10.9
Conditioned locomotion1.31.52.11.3-1.21.31.51.41.10.81.1
Cocaine response after cond. corrected0.30.41.5-0.20.20.2-0.4-0.4-1.01.20.0
Cocaine response after cond. not corrected1.01.12.1-1.01.0-0.5-1.2-1.2-1.51.1-0.8
Cocaine response before conditioning2.12.53.3-1.81.8-1.8-1.8-1.8-0.9-0.4-1.8
Saline control response1.21.63.61.1-1.11.01.11.01.91.70.1
Condit. Reinf. active minus inactive responses1.01.32.0-1.41.4-0.8-1.4-1.4-0.50.7-1.1
Condit. Reinf. active-inactive response ratio1.71.82.7-1.61.6-1.1-1.6-1.6-0.80.0-1.2
Condit. Reinf. active responses0.50.71.3-0.80.8-0.5-0.9-0.9-0.21.1-1.1
Condit. Reinf. inactive responses0.91.12.71.1-1.10.81.00.91.01.60.1
Condit. Reinf. lever presses0.10.20.3-0.50.5-0.0-0.4-0.4-0.50.3-0.2
Condit. Reinf. lever reinforcers received0.50.71.1-0.90.9-0.5-0.9-0.9-0.11.0-1.0
Pavlov. Cond. lever latency0.20.31.00.6-0.60.00.50.51.00.5-0.4
Pavlov. Cond. magazine entry latency1.21.43.70.9-0.91.81.01.00.50.61.9
Pavlov. Cond. change in total contacts0.20.21.0-0.20.20.8-0.1-0.10.0-0.01.0
Pavlov. Cond. index score0.10.20.7-0.20.20.6-0.2-0.1-0.40.10.8
Pavlov. Cond. latency score0.20.20.9-0.10.10.8-0.1-0.1-0.40.30.9
Pavlov. Cond. lever contacts0.10.10.3-0.10.10.30.10.0-0.4-0.10.6
Pavlov. Cond. magazine entry number0.20.20.80.2-0.2-0.70.20.20.3-0.3-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.7-0.10.1-0.5-0.2-0.20.40.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.40.40.5-0.3-0.3-0.6-0.20.8
Pavlov. Cond. response bias0.10.20.6-0.20.20.6-0.0-0.1-0.50.30.8
Conditioned reinforcement - actives1.01.04.1-0.80.8-0.9-0.8-0.8-2.0-0.7-0.5
Conditioned reinforcement - inactives3.43.917.6-0.91.0-1.2-0.6-0.7-4.2-2.9-0.7
Conditioned locomotion1.41.73.0-1.11.1-1.6-1.1-1.2-1.7-1.4-1.0
Intermittent access intake day 1-15 change4.24.121.60.7-0.6-0.01.31.1-2.7-4.60.6
Intermittent access intake escalation2.42.310.50.8-0.70.11.21.0-2.1-3.20.4
Intermittent access intake escalation 23.83.714.21.3-1.20.41.81.7-2.3-3.81.0
Intermitt. access day 1 inactive lever presses2.72.912.21.1-1.21.00.60.72.53.50.6
Intermitt. access day 15 inactive lever presses1.31.43.2-1.31.4-0.2-0.8-1.0-1.8-1.5-0.9
Intermitt. access escalation Index4.03.617.31.1-1.21.30.91.04.22.01.0
Intermittent access day 1 total infusions1.31.45.2-1.21.2-0.2-1.2-1.2-2.30.0-0.4
Intermittent access day 15 total infusions2.12.39.5-0.70.7-0.4-0.3-0.5-3.1-2.8-0.2
Intermittent access terminal intake (last 3 days)2.42.69.6-0.91.0-0.7-0.5-0.7-3.1-2.8-0.5
Intermittent access total infusions2.52.89.4-1.41.4-0.7-1.1-1.2-3.1-2.4-0.5
Intermittent access day 1 locomotion1.41.42.4-1.31.3-0.9-1.4-1.4-1.5-0.1-0.8
Intermittent access day 15 total locomotion0.91.01.7-0.80.8-1.3-1.0-1.0-1.10.4-1.2
Intermittent access total locomotion0.70.81.1-0.90.9-1.0-1.0-1.0-1.0-0.2-0.9
Intermittent access standard deviation0.30.30.90.5-0.40.50.60.5-0.2-0.90.1
Cocaine induced anxiety0.91.14.2-0.50.6-0.4-0.0-0.2-2.0-1.9-0.2
Post-drug Anxiety0.20.20.40.5-0.40.40.70.60.3-0.20.5
Baseline Anxiety1.51.63.91.3-1.31.11.01.12.01.21.0
Lifetime Intake3.43.812.1-1.51.6-0.7-1.1-1.3-3.5-3.1-0.5
Incentive Sensitization - Responses1.91.96.0-0.60.7-1.4-0.2-0.3-2.3-2.5-1.1
Incentive Sensitization - Breakpoint2.02.05.8-0.80.9-1.4-0.4-0.5-2.2-2.4-1.2
Progressive ratio test 1 active lever presses3.94.08.0-2.12.1-1.7-1.9-2.0-2.8-1.9-1.1
Progressive ratio test 1 breakpoint3.33.46.5-1.92.0-1.6-1.8-1.9-2.6-1.7-1.1
Progressive ratio test 1 inactive lever presses3.23.414.3-1.11.1-1.4-0.9-1.0-3.8-2.2-1.1
Progressive ratio test 2 active lever presses2.42.64.1-1.61.6-1.6-1.4-1.4-1.9-2.0-1.3
Progressive ratio test 2 breakpoint2.52.84.5-1.61.7-1.8-1.3-1.4-1.8-2.1-1.5
Progressive ratio test 2 inactive lever presses3.43.910.7-1.51.6-1.4-1.1-1.3-3.3-3.0-1.3
Total sessions with >9 infusions2.93.28.3-1.51.5-1.1-1.4-1.4-2.7-2.9-0.5
Short access day 1 total inactive lever presses1.01.12.4-0.80.8-0.6-1.3-1.30.61.5-1.0
Short access day 10 total inactive lever presses0.00.00.2-0.10.1-0.4-0.1-0.1-0.2-0.0-0.3
Short access day 1 total infusions2.83.07.6-1.51.6-0.8-1.2-1.4-2.8-2.6-1.0
Short access day 10 total infusions4.24.614.7-1.91.9-1.1-1.6-1.7-3.8-2.8-0.9
Short access total infusions3.13.49.1-1.61.7-0.6-1.2-1.4-3.0-2.9-0.7
Short access day 1 locomotion1.51.62.9-1.21.2-1.1-1.3-1.3-1.7-0.7-1.3
Short access day 10 total locomotion0.40.41.3-0.50.4-0.6-0.8-0.60.01.1-0.4
Short access total locomotion0.90.91.7-1.01.0-1.0-1.3-1.2-0.70.4-0.8
Compulsive drug intake0.30.31.00.4-0.40.40.50.5-0.2-1.00.7
One hour access (0.3 mA shock)6.37.427.6-1.31.5-1.2-0.6-0.9-5.0-5.3-0.4
One hour access (shock baseline)5.15.920.1-1.31.4-1.3-0.9-1.0-4.5-4.4-0.5
Number of responses in last shaping day4.95.07.0-2.62.6-1.9-2.3-2.5-1.6-1.9-2.3
Context. condit. distance diff. score0.10.20.4-0.30.3-0.4-0.4-0.4-0.10.4-0.6
Locomotion velocity, session 10.30.30.50.7-0.70.50.70.7-0.5-0.20.4
Locomotion distance, session 10.20.30.60.8-0.80.20.70.7-0.1-0.00.0
Locomotion velocity, session 22.12.43.71.6-1.61.41.71.70.9-1.21.9
Locomotion distance, session 20.60.81.21.1-1.10.51.11.10.7-0.70.7
Locomotion velocity, session 30.30.31.90.1-0.1-0.50.10.1-1.4-0.7-0.3
Locomotion distance, session 30.91.01.91.3-1.20.61.41.3-0.80.10.4
Stereotopy head waving bouts, day 33.13.75.2-2.12.1-2.1-2.3-2.3-1.4-0.1-2.0
Stereotopy head waving duration, day 31.31.52.8-1.41.4-1.2-1.7-1.6-0.40.3-1.2
Locomotion velocity, session 71.01.02.0-1.01.0-1.4-1.0-1.0-0.6-0.8-1.1
Locomotion distance, session 70.10.20.9-0.20.2-0.4-0.3-0.3-0.90.1-0.3
Stereotopy head waving bouts, day 70.40.51.0-0.60.6-0.9-0.7-0.7-0.1-0.3-1.0
Stereotopy head waving duration, day 70.30.40.6-0.60.5-0.8-0.7-0.60.0-0.5-0.8
Locomotion velocity, session 80.20.20.80.4-0.40.10.50.5-0.0-0.90.1
Locomotion distance, session 80.30.40.60.7-0.70.40.70.80.7-0.30.4
Degree of sensitization distance0.30.30.6-0.70.7-0.4-0.8-0.70.3-0.1-0.1
Degree of sensitization stereotypy0.00.00.20.1-0.1-0.10.10.10.2-0.5-0.1
Condit. Reinf. active minus inactive responses0.40.41.3-0.40.4-0.8-0.5-0.50.70.1-1.1
Condit. Reinf. active-inactive response ratio0.10.10.6-0.10.1-0.3-0.3-0.20.8-0.1-0.4
Condit. Reinf. active responses0.20.20.7-0.30.2-0.6-0.4-0.40.30.0-0.9
Condit. Reinf. inactive responses0.10.10.40.4-0.40.10.40.4-0.60.3-0.1
Incentive salience index mean0.10.20.4-0.30.3-0.6-0.3-0.30.5-0.2-0.7
Condit. Reinf. lever presses0.00.00.30.1-0.0-0.00.20.20.0-0.50.3
Time in familiar zone, hab. session 10.40.40.80.9-0.90.50.80.80.30.10.3
Time in novel zone, hab. session 10.60.61.1-1.01.0-0.6-1.0-1.00.1-0.1-0.5
Total zone transitions, hab. session 10.00.10.3-0.20.2-0.3-0.1-0.1-0.00.1-0.6
Total locomotion distance, hab. session 10.10.21.00.3-0.3-0.10.50.41.0-0.0-0.2
Locomotion velocity, hab. session 10.40.61.50.7-0.70.50.90.91.2-0.00.5
Time in familiar zone, hab. session 20.10.10.4-0.00.0-0.1-0.1-0.1-0.60.3-0.0
Time in novel zone, hab. session 20.10.10.2-0.30.3-0.2-0.2-0.20.4-0.4-0.2
Total zone transitions, hab. session 20.70.92.11.1-1.10.71.01.01.40.50.2
Total locomotion distance, hab. session 20.30.42.30.4-0.40.00.40.41.50.2-0.3
Locomotion velocity, hab. session 20.40.52.40.6-0.60.10.60.61.50.1-0.1
Novel to familiar place preference ratio0.10.10.6-0.10.10.1-0.1-0.10.50.7-0.2
Novelty place preference0.10.10.5-0.20.20.2-0.1-0.10.60.7-0.2
Time in novel zone, NPP test0.20.20.6-0.50.5-0.1-0.5-0.50.50.8-0.5
Total zone transitions, NPP test0.40.61.21.1-1.10.61.01.00.40.00.4
Total locomotion distance, NPP test0.30.41.10.7-0.70.40.80.71.10.30.2
Locomotion velocity, NPP test0.71.01.61.1-1.10.71.21.21.30.20.6
Pavlov. Cond. lever latency0.40.51.50.8-0.90.50.50.50.21.2-0.0
Pavlov. Cond. magazine entry latency0.40.62.20.00.00.50.50.5-0.0-1.31.5
Pavlov. Cond. change in total contacts0.40.40.7-0.70.7-0.5-0.8-0.8-0.30.3-0.6
Pavlov. Cond. index score0.20.31.2-0.20.20.20.20.20.3-1.10.8
Pavlov. Cond. latency score0.20.21.3-0.20.30.00.10.10.1-1.10.7
Pavlov. Cond. lever contacts0.20.30.6-0.70.7-0.4-0.5-0.50.1-0.80.0
Pavlov. Cond. magazine entry number0.60.72.4-0.50.4-0.9-0.8-0.8-0.41.0-1.6
Pavlov. Cond. intertrial magazine entries2.22.76.9-1.31.3-1.8-1.7-1.7-0.91.0-2.6
Pavlov. Cond. lever-magazine prob. diff.0.20.21.2-0.30.40.10.00.00.1-1.10.7
Pavlov. Cond. response bias0.10.20.4-0.60.6-0.0-0.4-0.4-0.2-0.40.5
Bone: apparent density0.10.20.50.1-0.00.40.20.30.7-0.60.7
Bone surface0.20.42.3-0.00.10.30.20.3-0.2-1.51.0
Bone volume0.10.20.60.00.00.30.20.20.2-0.80.7
Bone: connectivity density0.40.61.40.5-0.50.70.70.70.8-0.81.2
Bone: cortical apparent density0.60.72.00.6-0.60.40.90.90.3-1.41.1
Bone: cortical area0.81.26.8-0.20.30.30.40.40.1-2.61.6
Bone: cortical porosity0.80.95.5-0.70.7-0.4-0.3-0.30.2-2.30.6
Bone: cortical porosity1.01.15.1-1.01.0-0.6-0.7-0.60.1-2.30.3
Bone: cortical thickness0.50.92.90.00.00.80.50.50.6-1.61.7
Bone: cortical thickness0.40.52.4-0.30.30.10.10.1-0.5-1.60.9
Bone: cortical tissue density0.50.71.80.6-0.60.40.90.90.2-1.41.0
Bone: elastic displacement0.20.30.60.7-0.80.30.50.50.30.50.2
Bone: elastic work0.91.23.1-1.01.0-1.1-0.9-0.8-1.3-1.8-0.4
Bone: endosteal estimation0.30.72.6-0.40.4-1.0-0.2-0.2-1.1-1.6-0.4
Bone: endosteal perimeter0.30.61.20.9-0.80.11.11.10.2-1.00.5
Bone: final force0.40.63.2-0.40.5-0.50.0-0.0-1.0-1.80.3
Bone: final moment0.40.63.6-0.20.3-0.30.20.2-0.7-1.90.5
Bone: marrow area0.40.82.9-0.50.5-1.1-0.3-0.3-1.2-1.7-0.5
Bone: maximum diameter0.20.42.6-0.50.6-0.3-0.2-0.20.2-1.60.3
Bone: maximum force1.22.18.7-1.21.2-1.1-0.7-0.7-1.8-2.90.2
Bone: maximum moment1.01.89.4-1.01.0-0.9-0.5-0.5-1.4-3.10.4
Bone: minimum diameter1.01.85.10.7-0.60.91.21.20.9-2.31.9
Bone: periosteal estimation0.40.95.4-0.60.6-0.6-0.1-0.1-0.8-2.30.4
Bone: periosteal perimeter0.30.63.90.00.0-0.20.40.4-0.0-2.00.6
Bone: post-yield work0.60.82.00.6-0.50.80.80.80.3-1.11.4
Bone: stiffness0.71.24.2-1.11.1-0.4-0.6-0.6-1.2-2.00.6
Bone: tissue strength0.00.00.20.1-0.10.20.00.10.2-0.30.4
Bone: trabecular number0.30.41.00.6-0.60.70.50.61.00.50.5
Bone: trabecular spacing0.50.73.2-0.40.4-0.2-0.6-0.6-0.31.8-1.0
Bone: trabecular thickness0.60.74.2-0.00.1-0.00.40.40.2-2.10.9
Bone: trabecular tissue density0.10.10.6-0.30.4-0.1-0.1-0.10.3-0.80.1
Breakpoint value in progressive ratio session3.53.95.4-2.22.2-2.1-2.3-2.3-1.5-0.7-1.9
Distance traveled before self-admin0.50.51.10.8-0.80.50.60.70.7-0.11.1
Distance traveled after self-admin2.22.43.41.8-1.81.51.51.71.50.71.5
Delta time in closed arm before/after self-admin0.90.83.20.7-0.70.20.90.8-0.9-1.80.5
Delta time in open arm before/after self-admin0.20.20.8-0.10.10.20.10.0-0.6-0.90.3
Diff in mean of infusions in LGA sessions0.40.50.7-0.60.6-0.5-0.8-0.8-0.80.8-0.6
Extinction: sum of active levers before priming0.91.02.1-0.91.0-1.0-0.7-0.8-1.1-1.4-0.6
Active lever presses in extinction session 61.61.63.1-1.31.3-1.2-1.2-1.1-1.2-1.8-0.1
Delta distance traveled before/after self-admin0.40.51.30.5-0.50.60.80.7-0.5-1.10.5
Delta ambulatory time before/after self-admin0.50.53.00.2-0.10.20.50.4-0.7-1.70.1
Time in closed arm before self-admin1.21.43.30.9-0.91.51.01.01.80.91.2
Time in closed arm after self-admin1.41.53.61.0-1.01.30.90.91.91.40.9
Time in open arm before self-admin0.70.81.4-0.70.7-1.2-0.9-0.9-1.0-0.0-1.2
Time in open arm after self-admin0.60.61.8-0.60.6-0.6-0.5-0.6-1.3-1.0-0.4
Sum of active levers in priming session hrs 5-60.30.31.2-0.20.2-0.7-0.2-0.2-0.4-1.10.1
Time to tail flick, vehicle, before self-admin0.20.20.50.1-0.00.50.40.3-0.7-0.60.2
Time to tail flick, vehicle, after self-admin1.01.16.30.4-0.40.60.40.31.02.5-0.5
Time to tail flick, test, before self-admin1.81.83.0-1.51.5-0.7-1.4-1.5-1.40.4-1.7
Time to tail flick, test, after self-admin0.40.41.40.5-0.51.20.70.60.30.60.4
Delta time to tail flick, vehicle, before/after SA1.51.56.90.7-0.70.50.40.51.72.60.0
Delta time to tail flick, test, before/after SA3.02.73.61.9-1.91.71.91.91.30.31.7
Ambulatory time before self-admin0.70.81.50.9-1.00.50.50.71.01.20.9
Ambulatory time after self-admin1.31.52.11.4-1.41.11.41.50.8-0.31.4
Total heroin consumption3.84.66.6-2.32.3-2.2-2.6-2.5-1.51.3-2.2
Area under the delay curve0.20.20.50.0-0.0-0.7-0.1-0.1-0.5-0.7-0.2
Delay disc. indifference point, 0s delay2.32.510.91.1-1.1-0.71.31.3-1.2-3.31.1
Delay disc. indifference point, 16s delay1.11.11.8-1.01.0-1.2-1.3-1.3-0.50.6-1.3
Delay disc. indifference point, 2s delay0.40.51.5-0.30.3-0.8-0.2-0.3-1.2-1.0-0.6
Delay disc. indifference point, 24s delay0.70.72.1-0.70.6-0.3-0.9-0.9-0.51.4-0.9
Delay disc. indifference point, 4s delay1.01.12.41.1-1.10.11.21.2-0.2-1.51.1
Delay disc. indifference point, 8s delay0.40.42.60.2-0.2-0.80.20.2-0.3-1.60.0
Delay discount exponential model param0.20.20.60.2-0.20.80.30.30.70.50.5
Delay discount hyperbolic model param0.30.30.90.2-0.21.00.30.30.80.80.5
Fecal boli incidents, locomotor time 10.80.92.4-0.50.5-1.5-0.4-0.4-1.0-1.5-0.9
Change in fecal boli incidents, locomotor task0.10.10.3-0.00.00.00.0-0.00.60.4-0.3
Time >=10cm from walls, locomotor time 10.60.60.80.9-0.90.80.80.80.20.70.8
Bouts of movement, locomotor time 10.50.51.7-0.70.7-0.5-0.7-0.71.30.3-0.6
Total resting periods, locomotor time 10.20.21.5-0.20.2-0.0-0.2-0.21.20.4-0.2
Rest time, locomotor task time 11.11.32.40.9-0.91.21.11.11.50.41.5
Distance moved, locomotor task time 10.20.20.9-0.30.30.4-0.4-0.4-0.20.9-0.1
Vertical activity count, locomotor time 11.11.11.8-1.00.9-0.6-1.3-1.2-0.81.3-1.2
Time >=10cm from walls, locomotor time 21.61.72.31.4-1.41.41.41.41.30.21.5
Bouts of movement, locomotor time 21.61.74.7-1.21.3-1.1-1.0-1.1-2.2-0.7-1.3
Total resting periods, locomotor time 22.12.24.9-1.51.5-1.4-1.3-1.4-2.2-0.5-1.6
Rest time, locomotor task time 20.10.10.4-0.20.2-0.6-0.2-0.2-0.10.3-0.7
Distance moved, locomotor task time 20.70.82.10.7-0.71.20.80.80.5-0.51.4
Vertical activity count, locomotor time 20.10.10.30.2-0.30.50.30.3-0.4-0.20.6
Weight adjusted by age0.30.30.60.8-0.8-0.20.70.70.20.5-0.1
Seeking ratio, delayed vs. immediate footshock0.20.31.70.0-0.00.4-0.0-0.01.30.50.2
Locomotion in novel chamber0.70.82.3-0.60.6-1.5-0.6-0.60.1-1.5-0.7
Locomotion in novel chamber post-restriction0.70.84.3-0.60.60.4-0.6-0.62.10.80.1
Progressive ratio0.60.74.80.3-0.3-0.50.50.50.1-2.20.3
Food seeking constrained by brief footshock1.72.19.41.2-1.21.11.11.13.10.30.9
Seeking ratio, punishment vs. effort0.80.93.20.6-0.61.00.40.41.41.80.4
Run reversals in cocaine runway, females0.70.71.40.5-0.51.00.90.8-0.1-1.21.2
Run reversals in cocaine runway, males0.90.91.70.8-0.71.31.11.0-0.9-0.40.9
Latency to leave start box in cocaine runway0.20.20.6-0.10.1-0.8-0.2-0.2-0.70.2-0.5
Latency to leave start box in cocaine runway, F0.40.50.90.8-0.80.50.90.9-0.20.40.6
Latency to leave start box in cocaine runway, M2.22.13.6-1.31.2-1.9-1.7-1.6-1.5-0.0-1.7
Cd content in liver0.40.51.00.5-0.40.80.50.5-0.80.81.0
Co content in liver2.42.812.2-1.41.5-1.0-1.0-0.9-1.8-3.50.4
Cu content in liver3.64.46.12.1-2.12.52.02.02.12.02.0
Fe content in liver2.22.66.9-1.31.2-1.8-1.8-1.70.21.3-2.6
K content in liver0.40.42.1-0.20.2-0.7-0.2-0.2-0.4-1.5-0.5
Mg content in liver0.40.40.91.0-1.00.30.80.80.4-0.00.1
Mn content in liver1.82.03.1-1.31.2-1.8-1.2-1.3-1.4-1.5-1.7
Na content in liver0.50.52.80.5-0.50.30.40.41.7-0.60.4
Rb content in liver0.20.20.90.2-0.2-0.20.20.2-0.8-0.9-0.0
Se content in liver0.50.61.10.6-0.60.70.80.80.6-0.61.1
Sr content in liver5.85.38.2-2.92.9-2.0-2.5-2.5-2.1-2.3-0.6
Zn content in liver0.50.51.20.6-0.60.50.70.70.2-1.11.0