Lima1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000059801 0.1 0.08 1.1e-09 0.07 0.07 0.07 0.07 5.7e-08 1.4e-08 2.9e-08 4.0e-08
2 Brain gene expression ENSRNOG00000059801 0.07 0.05 2.6e-06 0.05 0.06 0.05 0.05 8.9e-06 2.2e-06 1.3e-05 1.6e-05
3 Eye gene expression ENSRNOG00000059801 0.38 0.2 1.6e-05 0.23 0.32 0.31 0.31 2.2e-04 6.6e-06 9.3e-06 1.2e-05
4 IL gene expression ENSRNOG00000059801 0.14 0.14 9.7e-03 0.03 0.06 0.03 0.03 6.9e-02 1.4e-02 6.1e-02 7.5e-02
5 LHb intron excision ratio chr7:130908211:130910972 0.15 0.14 7.1e-03 0.03 0.03 0.1 0.06 8.4e-02 8.4e-02 2.8e-03 2.0e-02
6 Liver alternative TSS ENSRNOT00000091702 0.03 0.03 9.9e-04 0.02 0.02 0.02 0.02 2.6e-03 5.2e-03 2.7e-03 3.8e-03
7 Liver alternative TSS ENSRNOT00000109357 0.03 0.03 1.4e-03 0.02 0.02 0.02 0.02 3.4e-03 6.4e-03 3.2e-03 4.8e-03
8 Liver gene expression ENSRNOG00000059801 0.04 0.04 5.4e-04 0.03 0.03 0.03 0.03 6.9e-04 5.9e-04 6.6e-04 7.4e-04
9 Liver intron excision ratio chr7:130967692:130985745 0.06 0.08 5.4e-05 0.04 0.04 0.04 0.04 5.8e-05 5.6e-05 3.9e-05 6.3e-05
10 Liver intron excision ratio chr7:130967692:131001423 0.04 0.05 2.0e-04 0.03 0.03 0.03 0.03 6.9e-04 5.3e-04 4.6e-04 6.0e-04
11 PL gene expression ENSRNOG00000059801 0.09 0.1 1.5e-03 0.03 0.02 0.02 0.03 2.1e-03 1.5e-02 1.5e-02 3.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail4.012.915.2-3.8-3.8-3.7-3.6-3.9-3.63.6-3.82.3-3.7-3.5
BMI without tail0.20.51.4-0.7-0.5-0.7-0.9-0.4-0.60.6-0.71.2-0.7-0.7
Body weight4.518.923.6-4.6-4.8-4.5-4.3-4.9-4.34.3-4.62.3-4.4-4.3
Epididymis fat weight0.00.00.2-0.2-0.2-0.1-0.1-0.3-0.10.1-0.2-0.4-0.10.0
Glucose0.30.41.00.60.50.60.70.50.6-0.60.6-1.00.60.6
Heart weight0.10.10.1-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.2-0.3-0.4
Left kidney weight0.92.53.0-1.7-1.6-1.7-1.7-1.5-1.51.5-1.71.5-1.6-1.6
Right kidney weight1.95.46.9-2.5-2.5-2.4-2.3-2.6-2.32.3-2.51.2-2.3-2.3
Tail length0.00.00.20.20.30.10.00.30.1-0.10.20.40.10.1
Length with tail1.55.76.8-2.5-2.6-2.4-2.3-2.6-2.42.4-2.51.4-2.4-2.4
Length without tail4.39.513.1-3.3-3.5-3.2-2.9-3.6-3.13.1-3.31.1-3.1-3.1
Liver weight, left1.62.53.0-1.6-1.7-1.6-1.5-1.7-1.61.6-1.60.9-1.6-1.7
Liver weight, right1.42.42.7-1.6-1.6-1.6-1.5-1.7-1.61.6-1.61.0-1.6-1.6
Parametrial fat weight1.12.13.21.61.81.51.31.81.4-1.41.6-0.41.51.5
Retroperitoneal fat weight1.03.43.61.91.91.91.81.81.9-1.91.9-1.71.91.9
Intraocular pressure4.66.58.62.72.92.62.42.92.6-2.62.7-1.02.62.6
Extensor digitorum longus weight4.317.219.0-4.3-4.3-4.3-4.2-4.4-4.14.1-4.33.0-4.1-4.1
Soleus weight1.02.93.1-1.8-1.7-1.7-1.7-1.7-1.71.7-1.81.4-1.7-1.7
Tibialis anterior weight2.910.112.1-3.2-2.9-3.3-3.5-2.8-3.13.1-3.23.4-3.1-3.1
Tibia length4.111.515.4-3.6-3.8-3.5-3.2-3.9-3.43.4-3.61.5-3.4-3.4
Number of licking bursts0.91.11.31.11.11.11.01.11.0-1.01.1-0.81.01.0
Food consumed during 24 hour testing period1.72.12.5-1.5-1.5-1.4-1.4-1.5-1.41.4-1.51.0-1.5-1.6
Times rat made contact with spout0.00.00.00.10.20.1-0.00.20.1-0.10.10.20.10.1
Mean time between licks in bursts0.00.00.10.20.10.20.30.10.2-0.20.2-0.20.20.2
Mean num. licks in bursts0.40.40.5-0.7-0.7-0.7-0.7-0.6-0.60.6-0.70.7-0.6-0.6
Std. dev. time between licks in bursts1.21.51.71.31.31.21.21.31.3-1.31.3-0.81.21.2
Water consumed over 24 hours0.10.10.20.30.20.30.30.20.3-0.30.3-0.50.20.2
Indifference point 0 sec5.79.29.63.13.03.13.13.03.1-3.13.1-2.93.03.0
Indifference point AUC0.20.20.30.40.50.40.30.60.5-0.50.4-0.10.60.4
Indifference point function ln k4.86.77.4-2.6-2.7-2.6-2.5-2.7-2.72.7-2.61.9-2.7-2.7
Indifference point function log k4.86.77.4-2.6-2.7-2.6-2.5-2.7-2.72.7-2.61.9-2.7-2.7
Delay discounting total patch changes 0 sec5.28.58.93.02.93.03.02.92.9-2.93.0-2.72.92.9
Delay discounting total patch changes 12 sec5.77.68.02.82.72.82.82.72.8-2.82.8-2.52.82.7
Delay discounting total patch changes 18 sec6.89.09.83.13.13.13.03.13.0-3.03.1-2.33.13.0
Delay discounting total patch changes 24 sec4.15.15.62.32.32.32.22.42.3-2.32.3-1.92.32.2
Delay discounting total patch changes 6 sec6.710.211.03.23.13.23.23.13.3-3.33.2-3.03.33.1
Delay discounting time to switch 0 sec2.43.74.32.02.01.91.82.11.9-1.92.0-1.32.02.0
Delay discounting water rate 0 sec3.35.25.7-2.3-2.3-2.3-2.3-2.4-2.32.3-2.31.7-2.3-2.3
Delay discounting water rate 12 sec2.74.15.2-2.1-2.2-2.0-1.8-2.3-2.22.2-2.11.0-2.1-2.1
Delay discounting water rate 18 sec0.50.60.9-0.7-0.8-0.7-0.7-0.8-0.90.9-0.70.7-0.9-0.9
Delay discounting water rate 24 sec4.56.27.2-2.5-2.6-2.5-2.4-2.7-2.62.6-2.52.0-2.6-2.5
Delay discounting water rate 6 sec5.68.28.9-2.9-2.9-2.9-2.9-2.9-3.03.0-2.92.2-2.9-2.9
Locomotor activity1.11.72.11.31.41.31.21.41.5-1.51.3-1.01.31.2
Locomotor testing distance3.05.06.02.32.32.32.22.42.4-2.42.3-1.62.22.1
Locomotor testing rearing2.13.34.11.81.91.81.72.02.0-2.01.8-1.21.81.8
Light reinforcement 10.71.32.41.21.41.10.91.61.0-1.01.20.41.11.0
Light reinforcement 20.10.21.4-0.10.1-0.2-0.30.2-0.20.2-0.11.2-0.2-0.1
Reaction time number correct1.21.72.3-1.3-1.4-1.3-1.1-1.5-1.51.5-1.30.6-1.3-1.3
Reaction time mean minus median5.26.89.02.73.02.72.43.02.6-2.62.7-1.12.62.6
Reaction time mean minus median AUC3.84.86.32.32.52.32.02.52.2-2.22.3-1.02.22.2
Reaction time num false alarms1.21.72.21.41.41.31.31.51.3-1.31.4-0.61.21.3
Reaction time num false alarms AUC1.41.92.71.51.61.41.31.61.4-1.41.5-0.51.31.3
Reaction time trials correct on left1.21.72.3-1.3-1.4-1.3-1.1-1.5-1.51.5-1.30.6-1.3-1.3
Reaction time trials on left0.91.31.8-1.1-1.3-1.1-1.0-1.3-1.41.4-1.10.5-1.1-1.1
Reaction time mean0.60.81.01.01.00.90.91.00.9-0.91.0-0.40.91.0
Reaction time mean AUC0.40.50.60.70.80.70.60.70.7-0.70.7-0.30.70.7
Median of all reaction times0.00.00.00.10.10.10.10.10.1-0.10.1-0.00.00.1
Reaction time omissions7.510.112.63.33.53.33.13.53.2-3.23.3-1.73.23.2
Reaction time false alarm rate1.62.33.21.61.71.51.41.81.7-1.71.6-0.61.51.5
Reaction time premature initiation rate4.35.87.62.52.72.52.32.82.5-2.52.5-1.12.52.4
Reaction time premature initiations1.72.43.31.71.71.61.51.81.5-1.51.7-0.71.61.6
Std. dev. reaction times4.66.37.92.62.82.62.42.82.6-2.62.6-1.32.52.5
Reaction time trials completed0.91.31.8-1.1-1.3-1.1-1.0-1.3-1.41.4-1.10.5-1.1-1.1
Reaction time trials AUC1.52.22.9-1.5-1.6-1.4-1.3-1.7-1.71.7-1.50.7-1.5-1.4
Social response proportion0.10.10.10.30.30.30.20.30.2-0.20.3-0.10.30.3
Social responses4.55.88.32.52.82.52.22.92.4-2.42.5-0.92.42.4
Social time0.30.40.6-0.6-0.5-0.6-0.6-0.5-0.60.6-0.60.8-0.6-0.6
Conditioned locomotion0.00.00.10.10.00.10.2-0.00.1-0.10.1-0.20.10.0
Cocaine response after cond. corrected0.00.00.00.0-0.00.00.00.00.0-0.00.00.00.00.0
Cocaine response after cond. not corrected0.20.20.30.50.50.50.40.60.5-0.50.5-0.10.50.5
Cocaine response before conditioning1.82.23.11.61.71.51.41.81.5-1.51.6-0.51.51.5
Saline control response0.00.00.20.0-0.10.00.1-0.10.1-0.10.0-0.40.0-0.0
Condit. Reinf. active minus inactive responses1.11.43.2-1.1-0.9-1.1-1.3-0.8-1.21.2-1.11.8-1.2-1.2
Condit. Reinf. active-inactive response ratio1.01.13.6-0.9-0.6-1.0-1.2-0.6-1.01.0-0.91.9-0.9-1.0
Condit. Reinf. active responses0.20.21.0-0.3-0.2-0.4-0.5-0.1-0.40.4-0.31.0-0.4-0.4
Condit. Reinf. inactive responses0.81.01.11.01.01.01.01.01.0-1.01.0-0.81.01.0
Condit. Reinf. lever presses0.00.00.0-0.0-0.0-0.00.0-0.00.0-0.0-0.0-0.00.00.0
Condit. Reinf. lever reinforcers received0.00.10.40.10.20.1-0.10.30.0-0.00.10.60.0-0.0
Pavlov. Cond. lever latency1.01.32.4-1.1-1.0-1.1-1.2-0.9-1.21.2-1.11.6-1.2-1.2
Pavlov. Cond. magazine entry latency0.30.32.20.2-0.00.30.5-0.20.4-0.40.2-1.50.40.4
Pavlov. Cond. change in total contacts0.40.60.9-0.9-0.9-0.8-0.8-1.0-0.80.8-0.90.1-0.7-0.8
Pavlov. Cond. index score0.60.73.10.60.40.70.90.30.8-0.80.6-1.80.80.8
Pavlov. Cond. latency score0.50.73.00.60.40.70.80.20.8-0.80.6-1.70.80.7
Pavlov. Cond. lever contacts0.81.11.41.01.01.01.10.91.1-1.11.0-1.21.11.1
Pavlov. Cond. magazine entry number0.20.32.30.10.3-0.0-0.30.5-0.20.20.11.5-0.1-0.1
Pavlov. Cond. intertrial magazine entries1.92.44.41.71.91.61.32.11.5-1.51.70.01.51.5
Pavlov. Cond. lever-magazine prob. diff.0.30.42.40.30.10.40.6-0.00.5-0.50.3-1.50.50.5
Pavlov. Cond. response bias0.40.61.10.70.60.70.80.50.8-0.80.7-1.00.80.8
Conditioned reinforcement - actives1.01.01.41.11.11.11.01.20.9-0.91.1-0.41.01.0
Conditioned reinforcement - inactives1.82.02.41.51.61.41.31.51.4-1.41.5-0.81.41.5
Conditioned locomotion0.10.10.20.40.50.40.30.50.1-0.10.40.10.30.3
Intermittent access intake day 1-15 change0.20.20.50.50.60.40.30.70.3-0.30.50.70.30.4
Intermittent access intake escalation0.10.11.10.20.30.1-0.10.3-0.10.10.21.00.00.0
Intermittent access intake escalation 20.20.20.80.30.60.30.10.60.2-0.20.30.90.30.2
Intermitt. access day 1 inactive lever presses0.30.30.60.60.80.60.40.80.3-0.30.60.50.50.5
Intermitt. access day 15 inactive lever presses0.10.10.50.30.50.30.20.50.0-0.00.30.70.20.2
Intermitt. access escalation Index0.70.70.80.80.80.90.90.80.7-0.70.8-0.80.80.8
Intermittent access day 1 total infusions1.11.21.51.21.21.21.21.21.0-1.01.2-0.61.11.2
Intermittent access day 15 total infusions1.51.72.51.51.61.41.31.61.1-1.11.5-0.21.31.4
Intermittent access terminal intake (last 3 days)1.51.62.51.41.61.41.21.61.1-1.11.4-0.11.21.3
Intermittent access total infusions1.41.62.41.41.51.31.21.61.1-1.11.4-0.21.21.3
Intermittent access day 1 locomotion1.31.31.61.31.21.31.31.21.0-1.01.3-0.91.11.2
Intermittent access day 15 total locomotion0.91.01.51.11.21.11.01.20.7-0.71.1-0.21.01.1
Intermittent access total locomotion3.43.84.72.12.22.12.02.11.7-1.72.1-1.22.02.1
Intermittent access standard deviation0.10.10.60.00.2-0.0-0.10.2-0.10.10.00.8-0.1-0.1
Cocaine induced anxiety0.80.91.1-1.0-1.0-1.0-0.9-1.0-1.01.0-1.00.5-0.9-0.9
Post-drug Anxiety4.95.46.2-2.4-2.5-2.4-2.3-2.5-2.42.4-2.41.5-2.3-2.3
Baseline Anxiety0.70.81.0-0.9-1.0-0.9-0.9-1.0-0.90.9-0.90.5-0.9-0.9
Lifetime Intake2.22.43.31.71.81.61.51.81.5-1.51.7-0.61.51.6
Incentive Sensitization - Responses0.40.41.0-0.6-0.5-0.6-0.7-0.4-0.70.7-0.61.0-0.7-0.5
Incentive Sensitization - Breakpoint0.30.30.9-0.5-0.4-0.5-0.6-0.3-0.60.6-0.51.0-0.6-0.5
Progressive ratio test 1 active lever presses7.98.29.03.03.03.03.03.02.7-2.73.0-2.22.93.0
Progressive ratio test 1 breakpoint6.76.97.62.82.82.72.72.72.5-2.52.8-1.92.62.7
Progressive ratio test 1 inactive lever presses2.02.22.91.61.71.61.51.71.3-1.31.6-0.61.51.6
Progressive ratio test 2 active lever presses1.81.92.61.51.61.51.31.61.2-1.21.5-0.51.41.4
Progressive ratio test 2 breakpoint1.92.13.11.61.71.51.41.81.3-1.31.6-0.41.51.5
Progressive ratio test 2 inactive lever presses1.01.11.71.21.31.11.01.30.9-0.91.2-0.01.01.1
Total sessions with >9 infusions1.41.51.91.31.41.31.21.41.2-1.21.3-0.61.21.3
Short access day 1 total inactive lever presses1.11.21.81.21.31.21.11.31.0-1.01.2-0.41.11.2
Short access day 10 total inactive lever presses0.10.10.3-0.2-0.1-0.2-0.3-0.2-0.20.2-0.20.5-0.2-0.2
Short access day 1 total infusions0.60.60.70.80.70.80.80.70.8-0.80.8-0.70.70.9
Short access day 10 total infusions2.62.93.21.81.71.81.81.71.7-1.71.8-1.51.71.7
Short access total infusions1.71.82.01.41.41.41.41.41.3-1.31.4-1.01.31.4
Short access day 1 locomotion0.20.20.20.50.50.50.50.50.4-0.40.5-0.30.40.5
Short access day 10 total locomotion0.10.20.20.40.40.40.40.40.4-0.40.4-0.30.40.4
Short access total locomotion0.50.50.60.80.80.80.70.70.6-0.60.8-0.40.70.7
Compulsive drug intake1.91.82.0-1.4-1.4-1.4-1.4-1.3-1.41.4-1.41.2-1.3-1.3
One hour access (0.3 mA shock)0.10.11.1-0.20.0-0.2-0.40.1-0.30.3-0.21.1-0.2-0.2
One hour access (shock baseline)0.00.00.40.00.1-0.0-0.10.2-0.10.10.00.6-0.1-0.0
Number of responses in last shaping day0.40.40.8-0.6-0.5-0.6-0.6-0.5-0.60.6-0.60.9-0.7-0.7
Context. condit. distance diff. score0.30.30.4-0.5-0.5-0.5-0.5-0.5-0.60.6-0.50.4-0.6-0.6
Locomotion velocity, session 14.44.85.92.12.02.22.31.92.2-2.22.1-2.42.22.2
Locomotion distance, session 12.83.63.92.02.02.01.92.01.9-1.92.0-1.41.91.9
Locomotion velocity, session 20.30.40.40.60.60.60.60.60.6-0.60.6-0.50.60.6
Locomotion distance, session 22.94.24.42.12.12.12.12.12.1-2.12.1-1.62.12.1
Locomotion velocity, session 34.55.25.82.42.42.42.32.42.3-2.32.4-1.62.32.3
Locomotion distance, session 32.83.14.41.92.01.81.62.11.7-1.71.9-0.61.71.7
Stereotopy head waving bouts, day 30.10.10.8-0.1-0.2-0.00.1-0.40.0-0.0-0.1-0.90.00.0
Stereotopy head waving duration, day 30.10.21.20.20.00.20.4-0.10.3-0.30.2-1.10.30.3
Locomotion velocity, session 73.23.55.11.81.71.92.01.61.9-1.91.8-2.31.91.9
Locomotion distance, session 74.15.25.52.32.32.32.32.22.3-2.32.3-2.12.32.3
Stereotopy head waving bouts, day 70.50.50.7-0.8-0.8-0.8-0.7-0.8-0.70.7-0.80.3-0.7-0.7
Stereotopy head waving duration, day 70.91.21.5-1.2-1.2-1.1-1.1-1.2-1.01.0-1.10.6-1.1-1.0
Locomotion velocity, session 80.60.71.80.70.60.70.90.50.9-0.90.7-1.40.90.9
Locomotion distance, session 81.01.51.81.31.31.31.21.31.2-1.21.3-0.81.21.2
Degree of sensitization distance0.00.00.3-0.0-0.2-0.00.1-0.20.0-0.0-0.0-0.60.00.0
Degree of sensitization stereotypy0.60.70.9-0.9-0.8-0.9-0.9-0.7-0.80.8-0.81.0-0.8-0.8
Condit. Reinf. active minus inactive responses0.10.10.10.30.30.30.20.30.2-0.20.3-0.20.20.2
Condit. Reinf. active-inactive response ratio0.20.20.3-0.4-0.4-0.4-0.4-0.5-0.50.5-0.40.2-0.5-0.5
Condit. Reinf. active responses0.70.80.90.91.00.90.91.00.9-0.90.9-0.70.90.9
Condit. Reinf. inactive responses2.83.43.81.91.91.81.81.91.9-1.91.9-1.31.91.9
Incentive salience index mean0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.1-0.1-0.1
Condit. Reinf. lever presses0.50.70.9-0.8-0.7-0.8-0.9-0.7-0.80.8-0.81.0-0.8-0.8
Time in familiar zone, hab. session 10.00.00.2-0.10.0-0.1-0.20.1-0.10.1-0.10.5-0.1-0.1
Time in novel zone, hab. session 10.00.00.1-0.1-0.2-0.1-0.1-0.2-0.20.2-0.1-0.2-0.2-0.2
Total zone transitions, hab. session 10.10.10.10.30.30.30.20.40.2-0.20.30.10.30.2
Total locomotion distance, hab. session 10.30.51.10.70.50.70.80.50.6-0.60.7-1.10.60.6
Locomotion velocity, hab. session 10.20.30.80.50.40.50.60.30.5-0.50.5-0.90.50.5
Time in familiar zone, hab. session 21.51.61.7-1.3-1.2-1.3-1.3-1.2-1.31.3-1.31.3-1.3-1.3
Time in novel zone, hab. session 21.71.72.21.31.21.31.41.21.3-1.31.3-1.51.31.3
Total zone transitions, hab. session 20.20.30.30.50.50.50.50.60.5-0.50.5-0.20.50.5
Total locomotion distance, hab. session 20.40.50.60.70.70.70.80.60.7-0.70.7-0.80.70.7
Locomotion velocity, hab. session 20.20.30.40.50.50.50.60.50.5-0.50.5-0.60.50.5
Novel to familiar place preference ratio1.41.51.8-1.3-1.3-1.2-1.2-1.3-1.21.2-1.30.7-1.2-1.2
Novelty place preference0.80.91.1-1.0-1.0-0.9-0.9-1.0-1.01.0-1.00.4-0.9-1.0
Time in novel zone, NPP test0.60.60.8-0.8-0.9-0.8-0.7-0.9-0.80.8-0.80.2-0.8-0.8
Total zone transitions, NPP test2.63.73.92.01.92.02.01.91.9-1.92.0-1.82.01.9
Total locomotion distance, NPP test3.44.75.12.22.12.22.32.12.2-2.22.2-2.02.22.2
Locomotion velocity, NPP test2.23.23.51.81.71.81.91.71.8-1.81.8-1.71.81.8
Pavlov. Cond. lever latency0.20.31.50.40.20.50.70.10.5-0.50.4-1.20.50.5
Pavlov. Cond. magazine entry latency1.21.63.2-1.1-1.0-1.2-1.3-0.9-1.31.3-1.11.8-1.3-1.3
Pavlov. Cond. change in total contacts1.51.53.4-1.2-0.9-1.2-1.4-0.9-1.21.2-1.21.8-1.2-1.2
Pavlov. Cond. index score0.91.12.7-1.0-0.8-1.0-1.2-0.7-1.01.0-1.01.6-1.0-1.0
Pavlov. Cond. latency score0.70.92.4-0.9-0.6-0.9-1.1-0.5-0.90.9-0.81.6-0.9-0.9
Pavlov. Cond. lever contacts0.20.21.6-0.30.0-0.3-0.60.1-0.30.3-0.21.3-0.3-0.3
Pavlov. Cond. magazine entry number0.50.61.70.70.50.70.90.40.8-0.80.7-1.30.80.8
Pavlov. Cond. intertrial magazine entries5.36.410.92.42.12.52.72.02.6-2.62.4-3.32.52.5
Pavlov. Cond. lever-magazine prob. diff.1.21.52.6-1.2-1.0-1.2-1.4-0.9-1.21.2-1.21.6-1.2-1.2
Pavlov. Cond. response bias0.40.51.6-0.6-0.4-0.6-0.8-0.3-0.70.7-0.61.3-0.6-0.7
Bone: apparent density6.711.014.9-3.5-3.7-3.4-3.1-3.9-3.33.3-3.51.5-3.4-3.3
Bone surface9.116.120.4-4.2-4.4-4.1-3.8-4.5-4.14.1-4.22.2-4.1-4.1
Bone volume8.514.317.0-3.9-4.1-3.9-3.7-4.1-3.83.8-3.92.5-3.8-3.8
Bone: connectivity density3.45.48.2-2.4-2.7-2.4-2.0-2.9-2.32.3-2.40.6-2.3-2.3
Bone: cortical apparent density0.30.40.40.60.60.60.60.60.6-0.60.6-0.40.70.6
Bone: cortical area5.48.210.9-3.0-3.2-2.9-2.7-3.3-2.92.9-3.01.2-2.9-2.9
Bone: cortical porosity0.20.21.3-0.2-0.1-0.2-0.40.0-0.40.4-0.21.1-0.4-0.4
Bone: cortical porosity0.10.10.90.10.20.0-0.10.3-0.10.10.10.9-0.1-0.1
Bone: cortical thickness1.42.33.3-1.6-1.7-1.6-1.4-1.8-1.51.5-1.60.4-1.5-1.5
Bone: cortical thickness0.30.31.00.50.40.50.60.40.6-0.60.5-1.00.60.6
Bone: cortical tissue density0.40.50.60.70.70.70.70.70.8-0.80.7-0.50.80.8
Bone: elastic displacement7.07.98.32.82.72.82.92.72.9-2.92.8-2.62.92.9
Bone: elastic work0.00.00.20.1-0.00.10.2-0.00.2-0.20.1-0.50.20.2
Bone: endosteal estimation7.215.418.4-4.0-4.2-4.0-3.8-4.3-4.04.0-4.02.5-4.0-4.0
Bone: endosteal perimeter6.613.715.7-3.8-3.9-3.8-3.6-4.0-3.73.7-3.82.5-3.8-3.7
Bone: final force10.016.419.1-4.2-4.3-4.1-4.0-4.4-4.14.1-4.22.7-4.1-4.1
Bone: final moment11.418.921.6-4.5-4.6-4.4-4.2-4.6-4.44.4-4.53.0-4.4-4.4
Bone: marrow area6.714.417.4-3.9-4.1-3.9-3.6-4.2-3.93.9-3.92.3-3.9-3.9
Bone: maximum diameter1.52.73.9-1.7-1.9-1.7-1.5-2.0-1.61.6-1.80.5-1.7-1.6
Bone: maximum force13.222.927.7-5.0-5.2-4.9-4.6-5.3-4.94.9-5.02.9-4.9-4.9
Bone: maximum moment14.925.930.6-5.3-5.5-5.2-4.9-5.5-5.25.2-5.33.3-5.2-5.2
Bone: minimum diameter8.014.817.7-4.0-4.1-3.9-3.7-4.2-3.93.9-4.02.4-3.9-3.9
Bone: periosteal estimation9.018.522.8-4.5-4.7-4.4-4.1-4.8-4.44.4-4.52.4-4.4-4.4
Bone: periosteal perimeter8.914.817.4-4.0-4.1-3.9-3.8-4.2-3.93.9-4.02.4-3.9-3.9
Bone: post-yield work8.111.013.3-3.4-3.6-3.3-3.1-3.6-3.43.4-3.42.0-3.4-3.4
Bone: stiffness17.627.831.5-5.4-5.6-5.4-5.1-5.6-5.45.4-5.43.6-5.4-5.4
Bone: tissue strength1.91.92.1-1.4-1.5-1.4-1.3-1.5-1.41.4-1.41.0-1.4-1.4
Bone: trabecular number3.65.68.1-2.5-2.7-2.4-2.1-2.9-2.42.4-2.50.8-2.4-2.4
Bone: trabecular spacing1.01.32.21.21.41.21.01.51.1-1.11.2-0.11.11.1
Bone: trabecular thickness0.60.72.1-0.7-0.6-0.8-0.9-0.5-0.80.8-0.71.5-0.8-0.8
Bone: trabecular tissue density1.01.33.7-1.0-0.8-1.1-1.2-0.7-1.11.1-1.01.9-1.1-1.1
Breakpoint value in progressive ratio session0.10.10.3-0.2-0.2-0.2-0.1-0.30.3-0.3-0.2-0.5-0.1-0.2
Distance traveled before self-admin2.62.83.31.71.61.71.71.61.8-1.81.7-1.61.71.7
Distance traveled after self-admin0.70.81.30.80.80.80.90.71.1-1.10.8-1.00.80.9
Delta time in closed arm before/after self-admin0.10.10.2-0.3-0.4-0.3-0.3-0.3-0.40.4-0.30.2-0.4-0.5
Delta time in open arm before/after self-admin3.63.54.01.92.01.81.72.02.0-2.01.9-1.21.91.9
Diff in mean of infusions in LGA sessions1.41.62.2-1.3-1.3-1.2-1.2-1.2-1.51.5-1.30.8-1.2-1.3
Extinction: sum of active levers before priming0.90.91.3-0.9-0.9-0.9-0.9-0.9-1.11.1-0.90.7-0.9-0.9
Active lever presses in extinction session 60.10.10.2-0.2-0.3-0.2-0.2-0.30.1-0.1-0.2-0.5-0.1-0.2
Delta distance traveled before/after self-admin0.20.20.3-0.5-0.4-0.5-0.5-0.5-0.50.5-0.50.5-0.5-0.4
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.2-0.3-0.3-0.2-0.20.2-0.30.4-0.4-0.3
Time in closed arm before self-admin0.70.81.4-1.1-1.1-1.0-0.9-1.2-0.60.6-1.00.2-0.9-0.8
Time in closed arm after self-admin0.40.40.6-0.7-0.7-0.7-0.6-0.7-0.40.4-0.70.2-0.6-0.7
Time in open arm before self-admin0.20.20.7-0.3-0.4-0.3-0.1-0.4-0.90.9-0.30.1-0.4-0.4
Time in open arm after self-admin0.20.20.30.50.50.50.50.60.3-0.30.5-0.30.50.5
Sum of active levers in priming session hrs 5-60.50.51.00.70.60.70.80.50.7-0.70.7-1.00.70.6
Time to tail flick, vehicle, before self-admin0.80.81.40.80.90.80.71.01.2-1.20.8-0.80.90.8
Time to tail flick, vehicle, after self-admin0.40.40.6-0.8-0.8-0.8-0.8-0.7-0.20.2-0.80.3-0.6-0.7
Time to tail flick, test, before self-admin0.20.20.30.40.40.40.40.40.5-0.50.4-0.30.30.5
Time to tail flick, test, after self-admin0.60.70.8-0.9-0.9-0.9-0.9-0.8-0.60.6-0.90.7-0.8-0.9
Delta time to tail flick, vehicle, before/after SA0.70.70.8-0.9-0.9-0.9-0.9-0.9-0.80.8-0.90.7-0.8-0.8
Delta time to tail flick, test, before/after SA0.80.70.9-0.9-0.8-0.9-1.0-0.8-0.60.6-0.90.9-0.9-0.9
Ambulatory time before self-admin4.24.44.72.12.22.12.12.22.2-2.22.1-1.52.12.1
Ambulatory time after self-admin1.82.02.61.41.51.41.31.41.6-1.61.4-0.91.31.4
Total heroin consumption1.01.21.6-1.2-1.3-1.1-1.0-1.3-1.11.1-1.20.4-1.1-1.0
Area under the delay curve1.11.21.3-1.1-1.1-1.1-1.1-1.1-1.21.2-1.10.9-1.2-1.1
Delay disc. indifference point, 0s delay2.02.22.3-1.5-1.5-1.5-1.5-1.5-1.51.5-1.51.3-1.5-1.4
Delay disc. indifference point, 16s delay0.90.91.0-1.0-1.0-1.0-0.9-1.0-1.01.0-1.00.7-1.0-1.0
Delay disc. indifference point, 2s delay1.92.22.4-1.5-1.5-1.5-1.4-1.5-1.61.6-1.51.2-1.5-1.4
Delay disc. indifference point, 24s delay0.60.60.8-0.8-0.9-0.8-0.7-0.9-0.70.7-0.80.2-0.8-0.9
Delay disc. indifference point, 4s delay1.11.21.4-1.1-1.0-1.1-1.1-1.0-1.01.0-1.11.2-1.1-1.0
Delay disc. indifference point, 8s delay1.41.51.8-1.2-1.4-1.2-1.1-1.3-1.31.3-1.30.6-1.3-1.2
Delay discount exponential model param1.11.21.31.11.11.11.11.11.1-1.11.1-0.91.11.0
Delay discount hyperbolic model param1.21.31.41.11.21.11.11.11.2-1.21.2-1.01.21.1
Fecal boli incidents, locomotor time 10.91.01.81.11.21.10.91.30.9-0.91.1-0.11.01.0
Change in fecal boli incidents, locomotor task0.30.30.6-0.6-0.7-0.5-0.4-0.8-0.50.5-0.6-0.5-0.4-0.5
Time >=10cm from walls, locomotor time 10.40.41.30.50.40.60.70.40.5-0.50.5-1.10.60.4
Bouts of movement, locomotor time 10.00.00.0-0.1-0.1-0.1-0.1-0.0-0.00.0-0.1-0.0-0.1-0.2
Total resting periods, locomotor time 10.30.40.40.60.60.60.60.60.6-0.60.6-0.60.60.4
Rest time, locomotor task time 10.60.70.80.90.90.90.80.90.7-0.70.9-0.70.80.7
Distance moved, locomotor task time 10.00.00.10.10.00.10.1-0.10.1-0.10.1-0.30.10.3
Vertical activity count, locomotor time 10.90.91.3-1.0-1.1-1.0-0.9-1.1-0.90.9-1.00.5-1.0-0.8
Time >=10cm from walls, locomotor time 20.30.30.60.60.70.60.60.70.5-0.50.6-0.20.60.5
Bouts of movement, locomotor time 23.33.53.8-1.9-1.9-1.9-1.8-1.9-1.91.9-1.91.5-1.9-1.9
Total resting periods, locomotor time 23.73.94.2-2.0-2.1-2.0-2.0-2.1-2.02.0-2.01.6-2.0-2.0
Rest time, locomotor task time 20.10.10.40.30.30.30.30.30.4-0.40.3-0.60.40.3
Distance moved, locomotor task time 20.10.10.20.30.30.30.30.20.2-0.20.3-0.30.30.4
Vertical activity count, locomotor time 20.10.10.3-0.3-0.3-0.3-0.3-0.3-0.40.4-0.30.5-0.3-0.3
Weight adjusted by age0.20.30.7-0.5-0.7-0.5-0.3-0.8-0.30.3-0.6-0.6-0.5-0.3
Seeking ratio, delayed vs. immediate footshock0.80.91.1-0.9-0.9-0.9-0.9-0.9-1.01.0-0.91.0-1.0-1.0
Locomotion in novel chamber2.73.44.3-1.8-1.7-1.9-2.0-1.6-1.81.8-1.82.1-1.9-1.8
Locomotion in novel chamber post-restriction0.50.61.1-0.7-0.6-0.7-0.8-0.6-0.80.8-0.71.0-0.7-0.8
Progressive ratio1.01.11.71.11.01.11.20.81.1-1.11.1-1.31.11.0
Food seeking constrained by brief footshock1.92.32.81.51.41.61.61.31.5-1.51.5-1.71.61.5
Seeking ratio, punishment vs. effort0.10.10.2-0.3-0.3-0.3-0.4-0.2-0.40.4-0.30.5-0.3-0.3
Run reversals in cocaine runway, females0.40.40.7-0.6-0.5-0.6-0.7-0.6-0.60.6-0.60.9-0.6-0.7
Run reversals in cocaine runway, males0.80.81.20.91.00.90.81.01.1-1.10.9-0.30.80.8
Latency to leave start box in cocaine runway0.00.00.20.00.00.00.00.1-0.20.20.00.5-0.2-0.2
Latency to leave start box in cocaine runway, F1.41.62.11.31.41.31.31.51.2-1.21.3-0.61.21.2
Latency to leave start box in cocaine runway, M2.52.42.6-1.6-1.6-1.6-1.5-1.6-1.61.6-1.61.2-1.6-1.6
Cd content in liver0.40.50.70.70.80.70.60.80.7-0.70.7-0.20.70.7
Co content in liver0.50.60.80.70.90.70.60.90.8-0.80.7-0.30.80.8
Cu content in liver0.20.20.4-0.5-0.6-0.5-0.4-0.6-0.50.5-0.5-0.1-0.5-0.5
Fe content in liver1.01.21.31.11.11.11.11.01.2-1.21.1-1.11.21.2
K content in liver0.10.10.70.30.20.30.40.10.3-0.30.3-0.80.30.3
Mg content in liver0.20.20.20.50.50.50.50.40.4-0.40.5-0.50.40.4
Mn content in liver0.10.20.2-0.4-0.4-0.4-0.4-0.4-0.40.4-0.40.3-0.4-0.4
Na content in liver0.30.30.50.50.50.50.50.50.6-0.60.5-0.70.60.6
Rb content in liver2.12.63.11.61.51.61.71.51.6-1.61.6-1.81.61.6
Se content in liver2.12.62.81.61.61.61.61.51.7-1.71.6-1.61.71.7
Sr content in liver0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.10.1-0.1-0.2-0.1-0.1
Zn content in liver2.52.83.31.71.81.71.61.81.6-1.61.7-1.11.71.6