Hub : Genes

Scarf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	alternative polyA	ENSRNOT00000088722	0.04	0.03	1.9e-04	0.01	0.03	0.02	0.01	2.2e-02	8.2e-04	3.2e-03	3.4e-02
2	Adipose	alternative polyA	ENSRNOT00000104013	0.04	0.03	2.0e-04	0.01	0.02	0.02	0.01	4.0e-02	8.8e-04	3.5e-03	6.2e-02
3	Adipose	isoform ratio	ENSRNOT00000088722	0.04	0.03	7.0e-04	0.03	0.01	0.02	-0	3.2e-04	1.6e-02	2.9e-03	6.8e-01
4	Adipose	isoform ratio	ENSRNOT00000104013	0.04	0.03	6.9e-04	0.02	0.01	0.02	-0	1.1e-03	1.6e-02	3.1e-03	7.0e-01
5	Adipose	intron excision ratio	chr10:60361389:60364985	0.03	0.03	8.9e-03	0.01	0	0	0	6.6e-02	7.9e-02	2.7e-01	1.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	1.0	3.2	4.3	1.6	-1.7	2.1	-2.1	-1.3
BMI without tail	0.2	0.4	0.9	0.9	-0.9	0.5	-0.5	0.2
Body weight	1.1	4.7	8.6	2.9	-2.9	1.6	-1.6	1.2
Epididymis fat weight	3.1	7.1	10.4	3.2	-3.2	2.7	-2.7	-0.4
Glucose	3.1	4.8	6.1	-2.4	2.5	-2.3	2.3	0.9
Heart weight	0.1	0.1	0.2	0.4	-0.4	0.1	-0.1	0.4
Left kidney weight	3.3	9.5	13.7	-1.9	2.0	-3.6	3.6	3.7
Right kidney weight	2.8	8.0	13.3	-1.5	1.6	-3.3	3.3	3.7
Tail length	1.7	5.2	17.3	1.8	-1.7	-1.0	1.0	4.2
Length with tail	0.8	3.0	8.2	1.9	-1.8	-0.3	0.3	2.9
Length without tail	0.8	1.9	3.2	1.8	-1.8	1.2	-1.2	0.5
Liver weight, left	1.0	1.6	5.3	0.9	-0.8	-0.8	0.8	2.3
Liver weight, right	0.6	1.0	2.5	1.1	-1.0	-0.1	0.1	1.6
Parametrial fat weight	6.7	13.0	21.5	4.6	-4.6	3.3	-3.3	0.8
Retroperitoneal fat weight	0.0	0.1	0.4	-0.0	0.0	-0.2	0.2	0.7
Intraocular pressure	0.8	1.1	3.5	-0.6	0.6	0.8	-0.8	-1.9
Extensor digitorum longus weight	5.3	21.2	30.0	3.9	-4.0	5.5	-5.5	-3.9
Soleus weight	3.0	8.9	14.6	3.8	-3.8	2.7	-2.7	0.8
Tibialis anterior weight	8.3	28.7	38.7	5.1	-5.2	6.2	-6.2	-3.6
Tibia length	0.8	2.4	6.5	0.3	-0.2	-1.6	1.6	2.5
Number of licking bursts	0.3	0.4	0.6	-0.8	0.8	-0.6	0.6	0.4
Food consumed during 24 hour testing period	0.3	0.3	0.4	0.7	-0.7	0.6	-0.6	-0.3
Times rat made contact with spout	1.5	1.8	3.2	-0.7	0.7	-1.5	1.5	1.8
Mean time between licks in bursts	0.3	0.5	1.7	0.5	-0.5	-0.2	0.2	1.3
Mean num. licks in bursts	0.2	0.3	0.7	0.3	-0.3	-0.5	0.5	0.9
Std. dev. time between licks in bursts	0.3	0.4	0.6	0.5	-0.5	0.8	-0.8	-0.7
Water consumed over 24 hours	0.7	0.8	2.7	0.2	-0.1	-0.8	0.8	1.6
Indifference point 0 sec	0.2	0.3	0.3	0.4	-0.4	0.6	-0.6	-0.6
Indifference point AUC	0.2	0.3	0.6	-0.8	0.7	-0.0	0.0	-0.6
Indifference point function ln k	0.6	0.9	1.1	1.0	-1.0	1.0	-1.0	-0.7
Indifference point function log k	0.6	0.9	1.1	1.0	-1.0	1.0	-1.0	-0.7
Delay discounting total patch changes 0 sec	0.2	0.3	0.6	0.3	-0.3	0.6	-0.6	-0.8
Delay discounting total patch changes 12 sec	0.6	0.8	0.9	-0.8	0.8	-0.9	0.9	0.9
Delay discounting total patch changes 18 sec	0.8	1.1	1.3	-0.9	0.9	-1.1	1.1	1.1
Delay discounting total patch changes 24 sec	0.8	1.0	1.4	-1.2	1.2	-1.0	1.0	0.4
Delay discounting total patch changes 6 sec	0.2	0.3	0.6	-0.7	0.7	-0.1	0.1	-0.8
Delay discounting time to switch 0 sec	1.5	2.2	5.1	-0.5	0.6	-1.7	1.7	2.3
Delay discounting water rate 0 sec	0.5	0.9	2.3	0.0	-0.1	1.0	-1.0	-1.5
Delay discounting water rate 12 sec	0.0	0.0	0.0	0.1	-0.1	0.1	-0.1	-0.1
Delay discounting water rate 18 sec	2.9	3.8	4.8	1.7	-1.8	2.2	-2.2	-1.7
Delay discounting water rate 24 sec	0.3	0.4	0.6	0.1	-0.1	0.8	-0.8	-0.8
Delay discounting water rate 6 sec	0.2	0.3	0.6	-0.7	0.7	-0.2	0.2	-0.8
Locomotor activity	0.0	0.1	0.2	0.2	-0.2	0.1	-0.1	0.4
Locomotor testing distance	0.0	0.0	0.1	0.1	-0.1	0.1	-0.1	0.3
Locomotor testing rearing	0.3	0.5	0.8	0.2	-0.2	0.9	-0.9	-0.7
Light reinforcement 1	0.0	0.0	0.1	-0.0	0.0	0.3	-0.3	-0.1
Light reinforcement 2	2.5	3.3	4.1	-1.6	1.6	-2.0	2.0	1.8
Reaction time number correct	0.1	0.1	0.1	0.3	-0.3	0.3	-0.3	0.1
Reaction time mean minus median	0.2	0.2	0.6	-0.4	0.4	0.2	-0.2	-0.8
Reaction time mean minus median AUC	1.1	1.5	2.7	0.5	-0.5	1.4	-1.4	-1.7
Reaction time num false alarms	0.8	1.1	3.7	-0.5	0.4	0.8	-0.8	-1.9
Reaction time num false alarms AUC	0.8	1.1	3.7	-0.6	0.5	0.7	-0.7	-1.9
Reaction time trials correct on left	0.1	0.1	0.1	0.3	-0.3	0.3	-0.3	0.1
Reaction time trials on left	0.1	0.1	0.1	0.3	-0.3	0.3	-0.3	0.1
Reaction time mean	0.1	0.1	0.1	-0.4	0.3	-0.3	0.3	-0.3
Reaction time mean AUC	0.2	0.3	0.5	-0.7	0.7	-0.4	0.4	-0.6
Median of all reaction times	0.2	0.3	0.4	-0.5	0.5	-0.6	0.6	-0.0
Reaction time omissions	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1	-0.1
Reaction time false alarm rate	0.6	0.8	2.9	-0.5	0.4	0.6	-0.6	-1.7
Reaction time premature initiation rate	0.5	0.7	0.9	0.7	-0.7	0.9	-0.9	-0.8
Reaction time premature initiations	0.7	0.9	1.3	0.8	-0.8	1.1	-1.1	-0.9
Std. dev. reaction times	0.2	0.2	0.8	-0.4	0.4	0.2	-0.2	-0.9
Reaction time trials completed	0.1	0.1	0.1	0.3	-0.3	0.3	-0.3	0.1
Reaction time trials AUC	0.1	0.1	0.1	0.3	-0.3	0.3	-0.3	0.0
Social response proportion	1.8	2.0	4.0	2.0	-2.0	0.7	-0.7	1.1
Social responses	1.4	1.8	3.1	1.8	-1.7	1.1	-1.1	0.5
Social time	2.5	3.3	5.0	2.2	-2.2	1.8	-1.8	-0.2
Conditioned locomotion	0.4	0.4	0.8	-0.9	0.9	-0.5	0.5	-0.5
Cocaine response after cond. corrected	0.1	0.1	0.3	0.6	-0.5	-0.1	0.1	0.1
Cocaine response after cond. not corrected	0.3	0.4	0.9	0.9	-0.9	0.2	-0.2	0.1
Cocaine response before conditioning	0.9	1.1	1.4	1.1	-1.1	1.2	-1.2	-0.2
Saline control response	0.6	0.7	1.1	0.6	-0.6	1.0	-1.0	-1.0
Condit. Reinf. active minus inactive responses	0.5	0.6	0.8	0.6	-0.6	0.9	-0.9	-0.9
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.1	-0.0	-0.2	0.2	-0.2
Condit. Reinf. active responses	1.1	1.6	2.6	0.7	-0.7	1.6	-1.6	-1.2
Condit. Reinf. inactive responses	2.2	2.7	5.1	0.6	-0.7	2.3	-2.3	-1.7
Condit. Reinf. lever presses	0.4	0.5	0.9	-0.9	0.9	0.2	-0.2	-0.8
Condit. Reinf. lever reinforcers received	1.0	1.4	2.4	0.5	-0.6	1.5	-1.5	-1.3
Pavlov. Cond. lever latency	1.1	1.5	2.4	1.6	-1.6	1.1	-1.1	-0.6
Pavlov. Cond. magazine entry latency	1.5	1.8	2.3	-1.0	1.0	-1.5	1.5	1.5
Pavlov. Cond. change in total contacts	0.9	1.3	1.4	-1.2	1.2	-1.1	1.1	1.0
Pavlov. Cond. index score	1.6	2.1	3.0	-1.7	1.7	-1.4	1.4	0.9
Pavlov. Cond. latency score	1.9	2.4	3.6	-1.9	1.9	-1.5	1.5	0.8
Pavlov. Cond. lever contacts	0.9	1.2	1.4	-1.2	1.2	-1.1	1.1	0.9
Pavlov. Cond. magazine entry number	1.7	2.1	2.6	1.2	-1.2	1.6	-1.6	-1.6
Pavlov. Cond. intertrial magazine entries	2.5	3.3	4.2	1.6	-1.6	2.1	-2.1	-1.7
Pavlov. Cond. lever-magazine prob. diff.	1.4	1.9	2.7	-1.6	1.6	-1.3	1.3	0.8
Pavlov. Cond. response bias	1.4	1.9	2.1	-1.3	1.4	-1.4	1.4	1.3
Conditioned reinforcement - actives	2.6	2.6	3.8	1.2	-1.2	1.9	-1.9	-1.5
Conditioned reinforcement - inactives	0.6	0.7	1.0	0.5	-0.5	1.0	-1.0	-0.9
Conditioned locomotion	0.1	0.1	0.3	-0.6	0.6	-0.0	0.0	-0.2
Intermittent access intake day 1-15 change	1.1	1.1	3.3	-0.7	0.7	0.8	-0.8	-1.8
Intermittent access intake escalation	0.9	0.9	1.6	-1.3	1.2	0.0	-0.0	-1.2
Intermittent access intake escalation 2	1.3	1.2	2.5	-1.6	1.6	-0.5	0.5	-0.9
Intermitt. access day 1 inactive lever presses	2.4	2.5	3.7	-1.9	1.9	-1.6	1.6	0.7
Intermitt. access day 15 inactive lever presses	0.5	0.6	1.2	-1.1	1.1	-0.4	0.4	-0.2
Intermitt. access escalation Index	2.6	2.3	5.3	1.8	-1.7	0.4	-0.4	2.3
Intermittent access day 1 total infusions	0.6	0.6	0.8	0.7	-0.7	0.9	-0.9	-0.7
Intermittent access day 15 total infusions	1.3	1.4	3.8	-0.0	-0.1	1.3	-1.3	-1.9
Intermittent access terminal intake (last 3 days)	1.7	1.9	2.7	0.9	-1.0	1.6	-1.6	-1.5
Intermittent access total infusions	0.8	0.9	2.0	0.2	-0.2	1.1	-1.1	-1.4
Intermittent access day 1 locomotion	0.2	0.3	0.3	-0.5	0.5	-0.5	0.5	0.5
Intermittent access day 15 total locomotion	0.3	0.3	0.7	-0.8	0.8	-0.1	0.1	-0.5
Intermittent access total locomotion	0.1	0.1	0.1	-0.3	0.3	0.0	-0.0	-0.2
Intermittent access standard deviation	1.9	2.0	6.3	-1.4	1.3	0.3	-0.3	-2.5
Cocaine induced anxiety	0.4	0.4	1.5	-0.5	0.5	0.2	-0.2	-1.2
Post-drug Anxiety	0.2	0.2	0.7	0.1	-0.2	0.3	-0.3	-0.8
Baseline Anxiety	0.1	0.1	0.4	0.3	-0.3	-0.0	0.0	0.6
Lifetime Intake	0.8	0.9	2.3	0.1	-0.1	1.1	-1.1	-1.5
Incentive Sensitization - Responses	0.1	0.1	0.5	-0.0	0.0	0.1	-0.1	-0.7
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	-0.1	0.1	-0.0	0.0	-0.6
Progressive ratio test 1 active lever presses	0.5	0.5	0.9	0.5	-0.5	0.9	-0.9	-0.6
Progressive ratio test 1 breakpoint	1.1	1.1	1.7	0.9	-0.9	1.3	-1.3	-0.7
Progressive ratio test 1 inactive lever presses	0.4	0.4	0.8	-0.9	0.9	-0.5	0.5	-0.1
Progressive ratio test 2 active lever presses	0.4	0.5	1.4	0.1	-0.2	0.6	-0.6	-1.2
Progressive ratio test 2 breakpoint	0.5	0.6	1.7	0.1	-0.1	0.7	-0.7	-1.3
Progressive ratio test 2 inactive lever presses	0.4	0.5	1.3	-0.5	0.4	0.5	-0.5	-1.2
Total sessions with >9 infusions	0.3	0.3	0.6	0.3	-0.3	0.7	-0.7	-0.4
Short access day 1 total inactive lever presses	0.2	0.2	0.3	0.6	-0.6	0.4	-0.4	-0.1
Short access day 10 total inactive lever presses	0.5	0.5	1.0	-0.2	0.3	-0.8	0.8	1.0
Short access day 1 total infusions	0.7	0.8	2.2	-0.8	0.7	0.5	-0.5	-1.5
Short access day 10 total infusions	0.9	1.0	2.1	0.4	-0.4	1.1	-1.1	-1.4
Short access total infusions	0.9	1.0	2.8	-0.2	0.2	1.0	-1.0	-1.7
Short access day 1 locomotion	0.3	0.3	0.5	-0.7	0.7	0.2	-0.2	-0.7
Short access day 10 total locomotion	0.4	0.4	0.8	-0.9	0.9	-0.5	0.5	0.1
Short access total locomotion	0.3	0.3	0.6	-0.8	0.7	0.2	-0.2	-0.5
Compulsive drug intake	0.3	0.3	1.1	0.4	-0.4	-0.3	0.3	1.1
One hour access (0.3 mA shock)	1.7	2.0	4.0	0.5	-0.6	1.6	-1.6	-2.0
One hour access (shock baseline)	1.2	1.4	3.3	0.2	-0.2	1.3	-1.3	-1.8
Number of responses in last shaping day	0.9	0.9	1.7	-1.3	1.3	-0.8	0.8	-0.2
Context. condit. distance diff. score	1.2	1.5	2.1	1.5	-1.5	1.2	-1.2	-0.5
Locomotion velocity, session 1	3.0	3.2	5.1	2.3	-2.3	1.7	-1.7	0.2
Locomotion distance, session 1	0.7	0.9	1.3	0.8	-0.8	1.2	-1.2	-0.6
Locomotion velocity, session 2	0.8	0.9	1.2	1.0	-1.0	1.1	-1.1	-0.3
Locomotion distance, session 2	1.7	2.4	3.2	1.4	-1.4	1.8	-1.8	-1.2
Locomotion velocity, session 3	4.6	5.3	6.9	-2.2	2.3	-2.6	2.6	1.7
Locomotion distance, session 3	0.1	0.1	0.1	-0.3	0.3	0.2	-0.2	-0.4
Stereotopy head waving bouts, day 3	0.4	0.5	2.1	0.2	-0.2	-0.3	0.3	1.5
Stereotopy head waving duration, day 3	0.3	0.3	0.5	-0.7	0.7	-0.3	0.3	0.6
Locomotion velocity, session 7	1.1	1.3	1.6	0.9	-0.9	1.3	-1.3	-1.2
Locomotion distance, session 7	1.8	2.3	2.9	1.3	-1.3	1.7	-1.7	-1.5
Stereotopy head waving bouts, day 7	0.9	1.0	1.3	1.0	-1.0	1.1	-1.1	0.4
Stereotopy head waving duration, day 7	1.1	1.4	1.9	1.2	-1.2	1.4	-1.4	0.3
Locomotion velocity, session 8	0.5	0.6	0.9	0.6	-0.6	1.0	-1.0	-0.7
Locomotion distance, session 8	2.0	3.0	4.3	2.1	-2.1	1.8	-1.8	-0.4
Degree of sensitization distance	1.1	1.1	1.8	1.3	-1.3	1.0	-1.0	-0.4
Degree of sensitization stereotypy	1.2	1.3	1.9	1.4	-1.4	1.2	-1.2	0.3
Condit. Reinf. active minus inactive responses	0.2	0.2	0.5	-0.1	0.2	-0.5	0.5	0.7
Condit. Reinf. active-inactive response ratio	2.6	2.8	4.9	-0.8	0.8	-2.0	2.0	2.2
Condit. Reinf. active responses	0.3	0.4	0.6	0.5	-0.6	0.8	-0.8	-0.6
Condit. Reinf. inactive responses	4.2	4.9	8.9	1.0	-1.1	2.6	-2.6	-3.0
Incentive salience index mean	0.1	0.2	0.5	0.2	-0.2	-0.4	0.4	0.7
Condit. Reinf. lever presses	0.5	0.7	1.4	1.2	-1.2	0.3	-0.3	0.7
Time in familiar zone, hab. session 1	1.6	1.6	4.0	0.3	-0.4	1.3	-1.3	-2.0
Time in novel zone, hab. session 1	1.5	1.5	3.7	-0.4	0.4	-1.3	1.3	1.9
Total zone transitions, hab. session 1	1.9	2.7	4.4	0.8	-0.8	2.1	-2.1	-1.9
Total locomotion distance, hab. session 1	0.6	0.8	1.4	0.6	-0.7	1.2	-1.2	-0.8
Locomotion velocity, hab. session 1	0.7	1.0	1.6	0.6	-0.6	1.3	-1.3	-1.1
Time in familiar zone, hab. session 2	1.7	1.8	2.8	1.0	-1.1	1.7	-1.7	-1.0
Time in novel zone, hab. session 2	4.3	4.4	6.6	-1.7	1.8	-2.6	2.6	1.7
Total zone transitions, hab. session 2	0.9	1.2	1.9	1.0	-1.0	1.4	-1.4	-0.5
Total locomotion distance, hab. session 2	0.1	0.1	0.2	0.4	-0.4	0.3	-0.3	0.2
Locomotion velocity, hab. session 2	0.0	0.1	0.1	0.3	-0.3	0.2	-0.2	0.2
Novel to familiar place preference ratio	0.4	0.4	1.4	-0.5	0.5	-0.1	0.1	-1.2
Novelty place preference	0.2	0.2	0.7	-0.3	0.2	-0.2	0.2	-0.8
Time in novel zone, NPP test	0.1	0.1	0.6	0.0	-0.0	0.1	-0.1	-0.8
Total zone transitions, NPP test	0.9	1.4	2.5	0.7	-0.7	1.6	-1.6	-0.8
Total locomotion distance, NPP test	0.2	0.3	0.6	-0.1	0.0	0.8	-0.8	-0.6
Locomotion velocity, NPP test	0.2	0.3	0.5	-0.6	0.5	0.4	-0.4	-0.7
Pavlov. Cond. lever latency	0.2	0.3	0.8	-0.1	0.0	0.6	-0.6	-0.9
Pavlov. Cond. magazine entry latency	0.3	0.4	0.9	1.0	-0.9	0.2	-0.2	0.3
Pavlov. Cond. change in total contacts	0.5	0.5	0.7	-0.6	0.7	-0.8	0.8	0.5
Pavlov. Cond. index score	0.3	0.4	0.7	0.8	-0.8	-0.1	0.1	0.8
Pavlov. Cond. latency score	0.4	0.5	1.4	0.8	-0.8	-0.3	0.3	1.2
Pavlov. Cond. lever contacts	0.2	0.2	0.6	0.2	-0.1	-0.5	0.5	0.8
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	-0.5	0.5	-0.1	0.1	-0.0
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.2	-0.2	0.1	1.0	-1.0	-1.1
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.6	0.8	-0.8	0.1	-0.1	0.5
Pavlov. Cond. response bias	0.1	0.2	0.4	0.6	-0.6	0.1	-0.1	0.2
Bone: apparent density	3.7	6.2	7.7	2.7	-2.7	2.8	-2.8	-1.0
Bone surface	3.3	5.8	7.8	2.3	-2.3	2.8	-2.8	-1.6
Bone volume	3.5	6.0	8.4	2.3	-2.4	2.9	-2.9	-1.5
Bone: connectivity density	5.4	8.5	11.0	2.9	-3.0	3.3	-3.3	-1.7
Bone: cortical apparent density	0.3	0.4	0.6	-0.8	0.8	-0.2	0.2	-0.8
Bone: cortical area	1.6	2.4	3.0	-1.7	1.7	-1.7	1.7	0.3
Bone: cortical porosity	0.1	0.1	0.2	0.4	-0.4	0.3	-0.3	0.4
Bone: cortical porosity	0.0	0.0	0.2	0.1	-0.1	-0.1	0.1	0.4
Bone: cortical thickness	5.1	8.5	11.7	-2.7	2.8	-3.4	3.4	1.9
Bone: cortical thickness	1.3	1.5	2.2	-0.7	0.7	-1.5	1.5	1.4
Bone: cortical tissue density	0.2	0.3	0.6	-0.6	0.6	-0.0	0.0	-0.8
Bone: elastic displacement	0.4	0.4	0.8	-0.9	0.9	-0.5	0.5	-0.2
Bone: elastic work	4.2	5.5	7.1	-2.3	2.3	-2.7	2.7	1.7
Bone: endosteal estimation	0.1	0.3	0.7	0.1	-0.1	0.6	-0.6	-0.8
Bone: endosteal perimeter	1.1	2.3	5.1	0.5	-0.6	1.7	-1.7	-2.3
Bone: final force	0.8	1.4	2.5	-0.4	0.5	-1.4	1.4	1.6
Bone: final moment	0.7	1.1	1.7	-0.5	0.5	-1.3	1.3	1.3
Bone: marrow area	0.1	0.3	0.7	0.1	-0.1	0.6	-0.6	-0.8
Bone: maximum diameter	0.5	0.8	3.4	-0.5	0.4	0.4	-0.4	-1.9
Bone: maximum force	0.9	1.6	2.3	-0.7	0.8	-1.5	1.5	1.4
Bone: maximum moment	0.7	1.3	1.9	-0.8	0.8	-1.4	1.4	1.1
Bone: minimum diameter	0.8	1.4	2.2	-0.9	0.9	-1.5	1.5	1.0
Bone: periosteal estimation	0.3	0.5	0.8	-0.9	0.9	-0.8	0.8	-0.1
Bone: periosteal perimeter	0.2	0.4	1.2	-0.6	0.6	0.0	-0.0	-1.1
Bone: post-yield work	0.2	0.3	0.6	0.8	-0.8	0.3	-0.3	0.3
Bone: stiffness	0.7	1.1	1.9	1.4	-1.4	0.6	-0.6	1.0
Bone: tissue strength	2.4	2.3	3.1	-1.3	1.4	-1.8	1.8	1.4
Bone: trabecular number	4.0	6.2	8.2	2.6	-2.6	2.9	-2.9	-1.2
Bone: trabecular spacing	0.7	0.8	1.1	-1.0	1.0	-0.9	0.9	0.6
Bone: trabecular thickness	0.3	0.4	0.4	0.6	-0.6	0.6	-0.6	-0.5
Bone: trabecular tissue density	2.1	2.9	3.6	-1.9	1.9	-1.9	1.9	0.6
Breakpoint value in progressive ratio session	0.9	1.0	1.8	1.3	-1.3	0.5	-0.5	0.9
Distance traveled before self-admin	1.9	2.0	2.6	-1.6	1.6	-1.5	1.5	0.5
Distance traveled after self-admin	0.1	0.2	0.6	-0.1	0.1	-0.3	0.3	0.7
Delta time in closed arm before/after self-admin	0.3	0.3	0.5	-0.7	0.7	-0.2	0.2	-0.5
Delta time in open arm before/after self-admin	0.8	0.7	1.3	1.2	-1.1	0.7	-0.7	0.3
Diff in mean of infusions in LGA sessions	0.6	0.7	1.2	1.0	-1.0	0.2	-0.2	1.1
Extinction: sum of active levers before priming	2.0	2.0	2.7	1.5	-1.5	1.6	-1.6	-0.6
Active lever presses in extinction session 6	1.3	1.3	1.7	1.2	-1.2	1.3	-1.3	-0.4
Delta distance traveled before/after self-admin	1.6	1.7	2.9	1.7	-1.7	1.1	-1.1	0.4
Delta ambulatory time before/after self-admin	1.3	1.4	2.3	1.5	-1.5	1.0	-1.0	0.3
Time in closed arm before self-admin	1.8	2.0	3.6	1.9	-1.9	1.2	-1.2	0.4
Time in closed arm after self-admin	0.0	0.0	0.0	-0.2	0.2	-0.2	0.2	0.1
Time in open arm before self-admin	5.2	5.5	7.6	-2.7	2.8	-2.4	2.4	0.8
Time in open arm after self-admin	0.9	1.0	1.4	-1.2	1.2	-1.0	1.0	0.4
Sum of active levers in priming session hrs 5-6	1.7	1.7	3.0	1.7	-1.7	1.0	-1.0	0.5
Time to tail flick, vehicle, before self-admin	5.9	6.0	7.6	2.7	-2.8	2.6	-2.6	-1.0
Time to tail flick, vehicle, after self-admin	1.3	1.4	2.6	0.4	-0.5	1.4	-1.4	-1.6
Time to tail flick, test, before self-admin	0.5	0.5	0.7	0.7	-0.7	0.8	-0.8	-0.5
Time to tail flick, test, after self-admin	0.2	0.2	0.3	0.6	-0.6	0.2	-0.2	0.3
Delta time to tail flick, vehicle, before/after SA	0.9	0.9	1.8	-1.3	1.3	-0.4	0.4	-0.8
Delta time to tail flick, test, before/after SA	0.0	0.0	0.1	0.0	-0.0	0.2	-0.2	-0.3
Ambulatory time before self-admin	2.6	2.7	3.7	-1.5	1.6	-1.9	1.9	1.2
Ambulatory time after self-admin	0.8	0.8	3.0	0.6	-0.5	-0.5	0.5	1.7
Total heroin consumption	3.3	3.9	6.2	2.5	-2.5	1.9	-1.9	0.1
Area under the delay curve	1.8	1.9	2.3	-1.4	1.4	-1.5	1.5	1.0
Delay disc. indifference point, 0s delay	0.1	0.1	0.2	0.1	-0.1	0.4	-0.4	0.2
Delay disc. indifference point, 16s delay	1.0	1.0	1.4	-1.0	1.0	-1.2	1.2	0.5
Delay disc. indifference point, 2s delay	1.2	1.3	1.6	-1.2	1.3	-1.1	1.1	0.9
Delay disc. indifference point, 24s delay	0.4	0.4	0.6	-0.5	0.5	-0.8	0.8	0.2
Delay disc. indifference point, 4s delay	0.9	1.0	1.5	-0.8	0.9	-1.0	1.0	1.2
Delay disc. indifference point, 8s delay	0.9	0.9	1.2	-0.9	0.9	-1.1	1.1	0.6
Delay discount exponential model param	1.8	1.9	2.4	1.3	-1.3	1.6	-1.6	-1.2
Delay discount hyperbolic model param	1.6	1.7	2.0	1.3	-1.3	1.4	-1.4	-1.1
Fecal boli incidents, locomotor time 1	0.1	0.1	0.1	0.3	-0.3	-0.2	0.2	0.1
Change in fecal boli incidents, locomotor task	0.4	0.4	0.7	-0.4	0.4	-0.8	0.8	0.8
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	0.2	-0.2	0.5	-0.5	-0.4
Bouts of movement, locomotor time 1	0.1	0.1	0.2	0.3	-0.4	0.3	-0.3	-0.5
Total resting periods, locomotor time 1	0.1	0.2	0.4	0.3	-0.3	0.3	-0.3	-0.7
Rest time, locomotor task time 1	0.2	0.2	0.9	-0.3	0.3	0.1	-0.1	-1.0
Distance moved, locomotor task time 1	0.1	0.1	0.2	0.1	-0.1	0.4	-0.4	-0.2
Vertical activity count, locomotor time 1	0.6	0.6	0.9	0.7	-0.7	1.0	-1.0	-0.6
Time >=10cm from walls, locomotor time 2	0.8	0.8	0.9	-0.9	0.9	-0.9	0.9	0.9
Bouts of movement, locomotor time 2	0.2	0.2	0.4	-0.3	0.3	-0.6	0.6	0.3
Total resting periods, locomotor time 2	0.0	0.0	0.0	0.0	-0.0	-0.2	0.2	-0.0
Rest time, locomotor task time 2	0.1	0.1	0.5	0.4	-0.4	0.0	-0.0	-0.7
Distance moved, locomotor task time 2	0.3	0.4	0.5	-0.7	0.7	0.5	-0.5	-0.4
Vertical activity count, locomotor time 2	0.2	0.3	0.5	-0.7	0.7	-0.2	0.2	0.4
Weight adjusted by age	1.1	1.3	2.2	0.9	-0.9	1.5	-1.5	-0.6
Seeking ratio, delayed vs. immediate footshock	1.4	1.6	3.0	-1.7	1.7	-1.0	1.0	-0.2
Locomotion in novel chamber	2.2	2.7	5.1	-2.3	2.2	-0.7	0.7	-1.7
Locomotion in novel chamber post-restriction	0.1	0.1	0.4	0.0	-0.0	0.2	-0.2	-0.6
Progressive ratio	0.5	0.6	1.9	-0.1	0.0	0.7	-0.7	-1.4
Food seeking constrained by brief footshock	0.1	0.1	0.2	-0.4	0.4	-0.2	0.2	0.0
Seeking ratio, punishment vs. effort	0.7	0.9	2.0	-0.5	0.5	-1.0	1.0	1.4
Run reversals in cocaine runway, females	0.4	0.4	0.8	-0.8	0.7	0.2	-0.2	-0.9
Run reversals in cocaine runway, males	0.6	0.5	1.6	-0.1	0.1	0.7	-0.7	-1.3
Latency to leave start box in cocaine runway	0.1	0.1	0.3	-0.3	0.3	-0.3	0.3	0.6
Latency to leave start box in cocaine runway, F	0.2	0.2	0.7	-0.1	0.1	-0.5	0.5	0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	0.1	-0.1	0.2	-0.2	0.4
Cd content in liver	1.2	1.3	1.7	0.9	-1.0	1.2	-1.2	-1.3
Co content in liver	0.2	0.2	0.3	-0.5	0.5	-0.5	0.5	0.5
Cu content in liver	0.9	1.1	1.7	-0.7	0.7	-1.3	1.3	1.1
Fe content in liver	0.3	0.4	1.0	0.6	-0.5	-0.3	0.3	1.0
K content in liver	1.6	1.6	5.8	0.2	-0.1	-1.0	1.0	2.4
Mg content in liver	0.0	0.0	0.1	-0.2	0.2	0.0	-0.0	0.0
Mn content in liver	0.3	0.3	0.4	0.5	-0.5	0.7	-0.7	-0.4
Na content in liver	3.3	3.5	4.3	-1.5	1.6	-2.1	2.1	2.0
Rb content in liver	1.3	1.7	2.4	0.8	-0.9	1.6	-1.6	-1.4
Se content in liver	1.0	1.2	1.7	-0.9	1.0	-1.3	1.3	0.9
Sr content in liver	0.9	0.8	1.0	0.9	-0.9	1.0	-1.0	-0.8
Zn content in liver	0.8	0.8	2.2	0.4	-0.4	0.9	-0.9	-1.5