Hub : Genes

Tbc1d22b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000059458 0.12 0.12 2.3e-06 0.05 0.05 0.06 0.05 4.3e-06 7.1e-06 5.3e-07 5.2e-06
2 BLA gene expression ENSRNOG00000059458 0.09 0.07 2.4e-04 0.08 0.06 0.06 0.08 7.1e-05 2.2e-04 4.2e-04 3.0e-05
3 Brain gene expression ENSRNOG00000059458 0.18 0.1 0.0e+00 0.2 0.21 0.21 0.21 3.8e-18 6.8e-19 5.1e-19 5.8e-19
4 IL gene expression ENSRNOG00000059458 0.43 0.3 5.5e-04 0.09 0.06 0.02 0.08 4.6e-03 1.7e-02 1.1e-01 5.8e-03
5 Liver gene expression ENSRNOG00000059458 0.12 0.08 0.0e+00 0.16 0.16 0.16 0.16 9.0e-18 7.4e-18 9.7e-18 1.1e-17
6 Liver mRNA stability ENSRNOG00000059458 0.04 0.04 6.6e-05 0.03 0.04 0.03 0.04 1.1e-04 5.4e-05 1.1e-04 6.2e-05
7 NAcc gene expression ENSRNOG00000059458 0.07 0.06 5.3e-06 0.05 0.07 0.05 0.06 7.5e-05 5.0e-06 9.8e-05 2.2e-05
8 NAcc isoform ratio ENSRNOT00000093855 0.03 0.02 9.2e-03 0.01 0.02 0.01 0.01 3.2e-02 1.5e-02 5.9e-02 5.4e-02
9 OFC gene expression ENSRNOG00000059458 0.19 0.16 4.7e-04 0.17 0.16 0.15 0.17 6.8e-05 1.4e-04 1.8e-04 7.2e-05
10 PL gene expression ENSRNOG00000059458 0.21 0.16 3.3e-08 0.12 0.09 0.1 0.11 2.2e-09 1.3e-07 4.7e-08 5.3e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail2.58.010.62.03.22.92.72.8-2.92.8-2.82.83.2
BMI without tail1.53.03.51.21.81.91.51.8-1.91.8-1.81.81.9
Body weight6.527.531.92.95.65.55.45.4-5.45.3-5.45.35.7
Epididymis fat weight1.74.05.70.32.42.21.82.1-2.11.9-2.01.92.3
Glucose0.20.20.60.60.80.40.00.4-0.50.3-0.30.30.7
Heart weight1.92.74.80.1-1.3-1.7-2.2-1.71.6-1.71.7-2.0-1.3
Left kidney weight2.77.79.51.53.12.82.92.9-2.82.9-2.92.83.0
Right kidney weight3.510.111.42.13.33.23.43.3-3.23.3-3.33.33.2
Tail length1.02.93.51.21.51.91.71.8-1.81.9-1.81.71.6
Length with tail2.07.49.01.12.72.93.02.9-2.82.9-2.92.82.7
Length without tail1.73.75.20.72.11.92.31.9-1.91.9-2.01.92.1
Liver weight, left4.06.59.80.32.12.73.12.7-2.62.8-2.83.02.1
Liver weight, right2.33.85.51.51.62.02.42.0-2.02.1-2.02.01.7
Parametrial fat weight1.32.54.40.51.21.62.11.7-1.41.7-1.72.11.2
Retroperitoneal fat weight1.65.46.72.12.62.52.32.3-2.32.2-2.22.12.6
Intraocular pressure1.11.52.7-0.41.11.21.61.3-1.11.3-1.31.61.1
Extensor digitorum longus weight0.20.70.9-0.5-0.8-0.8-0.7-0.90.9-0.90.9-0.9-0.9
Soleus weight0.61.62.71.51.61.30.81.2-1.31.1-1.10.91.6
Tibialis anterior weight0.62.23.1-0.3-1.3-1.5-1.5-1.71.6-1.81.7-1.7-1.3
Tibia length2.15.97.21.02.42.42.52.6-2.62.7-2.72.52.4
Number of licking bursts0.50.60.90.3-0.8-0.8-1.0-0.80.8-0.80.8-0.9-0.8
Food consumed during 24 hour testing period0.70.81.21.11.00.90.70.8-0.90.8-0.80.81.0
Times rat made contact with spout3.54.05.0-1.5-2.2-2.0-1.8-2.02.1-2.02.0-1.9-2.2
Mean time between licks in bursts0.60.81.4-0.2-0.9-1.0-1.2-0.90.9-0.90.9-0.9-0.9
Mean num. licks in bursts0.40.51.5-1.2-0.7-0.6-0.3-0.60.6-0.60.5-0.4-0.7
Std. dev. time between licks in bursts1.11.32.71.71.61.10.30.9-1.10.7-0.80.81.6
Water consumed over 24 hours1.01.22.00.1-0.9-1.1-1.4-1.21.1-1.21.2-1.3-0.8
Indifference point 0 sec0.40.61.01.00.60.80.90.7-0.70.7-0.70.80.7
Indifference point AUC0.00.10.1-0.3-0.4-0.2-0.1-0.20.3-0.20.2-0.0-0.2
Indifference point function ln k0.10.10.20.1-0.2-0.3-0.3-0.30.2-0.20.3-0.5-0.2
Indifference point function log k0.10.10.20.1-0.2-0.3-0.3-0.30.2-0.20.3-0.5-0.2
Delay discounting total patch changes 0 sec0.30.51.01.00.60.80.80.7-0.70.7-0.70.70.7
Delay discounting total patch changes 12 sec0.10.21.71.30.00.10.0-0.00.0-0.10.10.20.2
Delay discounting total patch changes 18 sec0.50.61.4-0.40.40.81.20.8-0.70.8-0.81.00.5
Delay discounting total patch changes 24 sec0.30.31.01.0-0.5-0.5-0.5-0.50.5-0.60.6-0.5-0.3
Delay discounting total patch changes 6 sec0.10.10.20.50.20.40.40.3-0.20.2-0.20.50.4
Delay discounting time to switch 0 sec1.21.82.60.31.61.31.11.4-1.41.3-1.41.51.6
Delay discounting water rate 0 sec0.20.31.11.1-0.4-0.3-0.3-0.50.3-0.40.5-0.8-0.4
Delay discounting water rate 12 sec0.20.31.0-1.0-0.5-0.3-0.2-0.40.4-0.40.4-0.6-0.6
Delay discounting water rate 18 sec0.81.01.7-1.2-1.1-1.0-0.7-1.01.0-0.90.9-0.9-1.3
Delay discounting water rate 24 sec0.30.50.9-0.9-0.7-0.6-0.7-0.60.6-0.50.6-0.6-0.9
Delay discounting water rate 6 sec0.10.10.4-0.3-0.4-0.2-0.3-0.30.3-0.30.3-0.6-0.5
Locomotor activity0.10.20.4-0.30.00.60.70.4-0.40.4-0.40.50.1
Locomotor testing distance0.00.10.30.30.10.60.20.2-0.30.2-0.20.10.1
Locomotor testing rearing1.01.62.20.61.21.51.31.3-1.31.3-1.31.31.1
Light reinforcement 12.13.84.51.82.02.11.82.0-2.02.0-2.01.92.0
Light reinforcement 22.33.14.40.51.81.71.71.9-1.91.9-1.92.11.7
Reaction time number correct0.40.61.60.80.30.61.30.7-0.60.8-0.80.80.5
Reaction time mean minus median0.40.53.8-2.0-0.4-0.20.40.00.20.1-0.10.2-0.6
Reaction time mean minus median AUC0.40.54.0-2.0-0.2-0.10.60.20.00.2-0.20.4-0.3
Reaction time num false alarms0.20.31.51.2-0.5-0.4-0.2-0.50.5-0.40.5-0.6-0.4
Reaction time num false alarms AUC0.71.02.01.4-0.9-0.8-0.7-1.01.0-1.01.0-1.2-0.8
Reaction time trials correct on left0.40.61.60.80.30.61.30.7-0.60.8-0.80.80.5
Reaction time trials on left0.40.51.60.70.30.61.30.7-0.50.8-0.70.80.5
Reaction time mean0.40.52.9-1.70.40.40.60.5-0.40.4-0.50.60.2
Reaction time mean AUC0.60.83.0-1.70.60.70.90.8-0.60.7-0.80.90.4
Median of all reaction times0.40.61.7-1.30.80.60.60.7-0.60.6-0.60.70.6
Reaction time omissions0.30.43.3-1.8-0.5-0.30.1-0.20.4-0.20.20.0-0.6
Reaction time false alarm rate1.01.52.30.8-1.0-1.1-1.4-1.31.2-1.31.3-1.5-1.0
Reaction time premature initiation rate0.10.20.50.5-0.2-0.2-0.3-0.40.3-0.50.5-0.7-0.1
Reaction time premature initiations0.10.21.21.10.20.30.50.1-0.10.1-0.1-0.10.3
Std. dev. reaction times0.40.54.5-2.1-0.3-0.20.3-0.10.2-0.10.00.0-0.5
Reaction time trials completed0.40.51.60.70.30.61.30.7-0.50.8-0.70.80.5
Reaction time trials AUC0.30.51.50.60.30.61.20.7-0.50.8-0.70.80.5
Social response proportion0.40.52.81.70.70.40.20.4-0.50.4-0.30.30.7
Social responses0.20.32.21.50.50.10.00.0-0.2-0.00.0-0.10.4
Social time0.20.20.30.1-0.5-0.6-0.3-0.60.6-0.50.5-0.6-0.4
Conditioned locomotion2.32.83.31.71.51.71.81.7-1.61.7-1.71.61.6
Cocaine response after cond. corrected1.41.62.81.21.71.21.01.2-1.31.1-1.11.11.7
Cocaine response after cond. not corrected1.31.52.41.21.51.11.01.1-1.21.0-1.11.11.5
Cocaine response before conditioning0.00.10.2-0.0-0.5-0.10.1-0.20.3-0.10.1-0.0-0.5
Saline control response0.60.81.20.40.81.11.00.9-0.80.9-0.90.90.8
Condit. Reinf. active minus inactive responses0.81.01.40.2-0.9-1.1-1.0-1.11.2-1.21.1-1.1-1.0
Condit. Reinf. active-inactive response ratio0.40.40.91.0-0.3-0.6-0.7-0.60.6-0.70.7-0.9-0.3
Condit. Reinf. active responses0.71.01.4-0.2-1.1-1.1-0.9-1.11.2-1.11.1-0.9-1.1
Condit. Reinf. inactive responses0.10.10.6-0.8-0.20.00.30.10.00.1-0.10.5-0.2
Condit. Reinf. lever presses3.44.75.7-1.3-2.3-2.3-2.1-2.32.4-2.32.3-1.9-2.3
Condit. Reinf. lever reinforcers received1.42.02.6-0.5-1.5-1.5-1.3-1.51.6-1.61.5-1.3-1.5
Pavlov. Cond. lever latency2.02.84.01.32.01.71.31.7-1.81.7-1.71.32.0
Pavlov. Cond. magazine entry latency0.10.10.4-0.60.10.30.50.3-0.20.3-0.30.40.1
Pavlov. Cond. change in total contacts1.42.02.7-1.2-1.6-1.4-1.1-1.41.6-1.51.4-1.2-1.7
Pavlov. Cond. index score0.70.91.4-1.0-1.2-0.9-0.5-0.91.1-0.90.9-0.6-1.2
Pavlov. Cond. latency score0.40.50.9-0.8-0.9-0.7-0.4-0.70.8-0.70.7-0.5-0.9
Pavlov. Cond. lever contacts1.62.33.6-1.4-1.9-1.5-1.0-1.51.7-1.51.5-1.1-1.9
Pavlov. Cond. magazine entry number0.10.10.40.60.2-0.1-0.3-0.1-0.0-0.10.1-0.20.2
Pavlov. Cond. intertrial magazine entries0.60.81.4-0.2-0.8-1.0-1.2-0.90.8-0.80.9-0.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-1.0-0.9-0.7-0.3-0.70.8-0.70.6-0.4-1.0
Pavlov. Cond. response bias1.21.62.7-1.6-1.6-1.1-0.6-1.21.4-1.21.1-0.7-1.6
Conditioned reinforcement - actives0.90.92.71.60.90.90.90.8-0.70.7-0.70.80.9
Conditioned reinforcement - inactives0.20.20.4-0.1-0.6-0.4-0.5-0.50.5-0.50.4-0.4-0.6
Conditioned locomotion1.01.34.52.10.91.01.00.9-0.90.9-0.90.91.1
Intermittent access intake day 1-15 change0.30.30.8-0.60.00.50.80.5-0.30.6-0.60.9-0.1
Intermittent access intake escalation0.60.61.3-0.50.30.71.10.8-0.50.8-0.81.20.2
Intermittent access intake escalation 20.40.40.8-0.3-0.9-0.5-0.4-0.60.7-0.50.5-0.4-0.9
Intermitt. access day 1 inactive lever presses0.60.75.72.40.50.2-0.4-0.0-0.2-0.10.1-0.40.5
Intermitt. access day 15 inactive lever presses0.60.71.1-0.00.60.91.00.9-0.70.9-0.91.10.6
Intermitt. access escalation Index0.60.51.3-1.2-0.6-0.7-0.8-0.60.6-0.60.6-0.7-0.6
Intermittent access day 1 total infusions0.30.30.5-0.2-0.7-0.6-0.4-0.60.6-0.60.6-0.7-0.6
Intermittent access day 15 total infusions0.00.00.10.3-0.20.10.30.10.00.1-0.10.3-0.1
Intermittent access terminal intake (last 3 days)0.30.31.61.30.30.40.40.4-0.30.4-0.40.30.4
Intermittent access total infusions0.10.10.20.5-0.4-0.3-0.2-0.30.3-0.30.3-0.3-0.4
Intermittent access day 1 locomotion0.40.42.91.70.40.50.50.4-0.40.4-0.40.20.5
Intermittent access day 15 total locomotion3.33.55.41.61.52.02.31.9-1.82.0-2.02.01.6
Intermittent access total locomotion1.11.22.11.00.71.21.51.1-1.01.2-1.21.20.8
Intermittent access standard deviation1.31.45.12.21.01.10.90.9-1.00.9-0.91.01.1
Cocaine induced anxiety0.30.30.7-0.9-0.7-0.5-0.4-0.40.5-0.40.4-0.2-0.8
Post-drug Anxiety0.50.50.7-0.6-0.8-0.7-0.8-0.70.8-0.70.7-0.6-0.8
Baseline Anxiety0.10.10.40.70.2-0.1-0.5-0.20.1-0.30.3-0.50.2
Lifetime Intake0.10.21.31.20.10.20.30.2-0.20.2-0.20.20.2
Incentive Sensitization - Responses1.41.41.7-1.3-1.3-1.2-1.0-1.21.3-1.21.1-1.0-1.3
Incentive Sensitization - Breakpoint1.11.12.4-1.5-1.1-1.0-0.8-0.91.1-0.90.9-0.7-1.2
Progressive ratio test 1 active lever presses0.10.11.21.10.20.10.1-0.0-0.0-0.10.0-0.10.1
Progressive ratio test 1 breakpoint0.20.22.21.50.30.20.10.0-0.1-0.10.0-0.10.3
Progressive ratio test 1 inactive lever presses0.91.02.41.50.91.01.00.9-0.80.8-0.90.91.0
Progressive ratio test 2 active lever presses0.00.00.10.3-0.1-0.10.2-0.10.2-0.20.1-0.0-0.1
Progressive ratio test 2 breakpoint0.00.00.1-0.1-0.2-0.20.1-0.20.3-0.20.2-0.1-0.3
Progressive ratio test 2 inactive lever presses0.50.60.90.5-0.9-0.7-0.5-0.80.9-0.70.8-0.8-0.9
Total sessions with >9 infusions0.30.42.61.60.50.40.30.3-0.30.2-0.20.20.5
Short access day 1 total inactive lever presses0.10.20.50.7-0.3-0.3-0.6-0.30.3-0.30.4-0.4-0.3
Short access day 10 total inactive lever presses0.00.00.10.3-0.00.2-0.10.0-0.00.0-0.00.0-0.0
Short access day 1 total infusions0.70.81.11.0-0.6-0.8-1.0-0.90.8-0.90.9-1.0-0.6
Short access day 10 total infusions0.30.32.91.7-0.1-0.00.1-0.10.1-0.10.1-0.3-0.0
Short access total infusions0.30.43.31.80.40.20.10.1-0.20.1-0.10.00.4
Short access day 1 locomotion0.60.75.82.40.60.2-0.10.0-0.1-0.10.0-0.10.6
Short access day 10 total locomotion2.22.421.74.70.60.0-0.7-0.30.0-0.40.4-0.70.7
Short access total locomotion2.02.118.14.21.00.60.10.3-0.50.3-0.2-0.11.0
Compulsive drug intake2.22.23.92.0-0.7-1.3-2.0-1.41.2-1.51.5-1.9-0.7
One hour access (0.3 mA shock)1.01.11.40.0-1.2-1.1-1.1-1.11.2-1.11.1-1.0-1.2
One hour access (shock baseline)0.30.43.0-1.7-0.50.00.50.20.10.2-0.20.5-0.4
Number of responses in last shaping day3.03.125.95.10.7-0.1-1.3-0.50.1-0.60.6-1.00.7
Context. condit. distance diff. score0.20.20.4-0.6-0.4-0.4-0.6-0.50.5-0.60.5-0.4-0.4
Locomotion velocity, session 10.90.91.2-1.1-1.0-1.0-0.7-1.01.1-1.01.0-0.9-1.0
Locomotion distance, session 13.34.34.9-1.7-2.2-2.2-2.1-2.12.1-2.12.1-2.0-2.2
Locomotion velocity, session 20.30.40.9-0.9-0.6-0.6-0.6-0.50.5-0.50.5-0.5-0.7
Locomotion distance, session 20.71.01.3-0.6-1.1-1.0-1.1-1.01.0-1.11.0-1.0-1.1
Locomotion velocity, session 30.20.20.4-0.50.10.40.70.5-0.30.5-0.50.60.1
Locomotion distance, session 30.40.40.6-0.7-0.8-0.7-0.5-0.60.7-0.60.6-0.3-0.8
Stereotopy head waving bouts, day 31.72.12.61.11.41.51.61.5-1.51.5-1.51.51.3
Stereotopy head waving duration, day 30.20.20.40.30.60.60.30.5-0.60.5-0.50.40.6
Locomotion velocity, session 70.10.20.5-0.6-0.7-0.30.1-0.20.3-0.10.2-0.1-0.7
Locomotion distance, session 70.91.22.1-0.4-1.5-1.1-0.8-1.11.1-1.01.1-1.0-1.4
Stereotopy head waving bouts, day 70.30.30.5-0.40.40.50.70.6-0.50.6-0.60.70.3
Stereotopy head waving duration, day 70.81.01.5-0.10.91.01.11.1-1.01.2-1.11.20.8
Locomotion velocity, session 80.00.00.1-0.3-0.10.10.2-0.00.1-0.10.00.0-0.1
Locomotion distance, session 80.71.11.4-0.9-1.1-1.0-1.2-1.01.0-1.11.0-1.0-1.1
Degree of sensitization distance0.10.10.40.70.10.20.10.1-0.20.1-0.0-0.10.1
Degree of sensitization stereotypy0.10.10.7-0.9-0.4-0.2-0.0-0.20.3-0.10.1-0.1-0.5
Condit. Reinf. active minus inactive responses1.01.11.5-0.7-1.1-1.2-1.1-1.11.1-1.11.1-1.0-1.1
Condit. Reinf. active-inactive response ratio0.10.10.2-0.4-0.2-0.4-0.4-0.20.3-0.20.2-0.1-0.2
Condit. Reinf. active responses0.40.50.7-0.4-0.8-0.8-0.4-0.70.8-0.70.7-0.6-0.8
Condit. Reinf. inactive responses0.50.51.0-0.2-1.0-0.8-0.3-0.80.9-0.70.7-0.6-1.0
Incentive salience index mean0.40.50.7-0.5-0.7-0.8-0.8-0.70.8-0.70.7-0.7-0.7
Condit. Reinf. lever presses0.00.10.2-0.3-0.1-0.3-0.4-0.20.2-0.20.2-0.2-0.1
Time in familiar zone, hab. session 10.00.00.1-0.3-0.2-0.10.2-0.10.3-0.20.10.0-0.1
Time in novel zone, hab. session 10.40.40.60.60.70.60.30.7-0.70.7-0.70.60.6
Total zone transitions, hab. session 12.73.84.8-0.5-2.1-2.0-1.9-2.12.1-2.12.1-2.2-2.1
Total locomotion distance, hab. session 11.82.63.1-0.6-1.7-1.6-1.6-1.71.7-1.71.7-1.8-1.7
Locomotion velocity, hab. session 11.62.43.1-0.3-1.5-1.5-1.5-1.61.6-1.71.7-1.8-1.6
Time in familiar zone, hab. session 21.51.54.0-2.0-1.2-1.1-1.0-1.11.1-1.11.1-1.1-1.3
Time in novel zone, hab. session 21.21.21.80.71.11.01.01.2-1.11.1-1.21.31.1
Total zone transitions, hab. session 20.30.40.6-0.5-0.7-0.6-0.8-0.60.6-0.60.6-0.7-0.8
Total locomotion distance, hab. session 22.22.93.4-1.1-1.8-1.7-1.8-1.71.7-1.71.7-1.7-1.9
Locomotion velocity, hab. session 22.63.54.2-1.1-2.0-1.9-1.9-1.91.9-1.91.9-1.9-2.1
Novel to familiar place preference ratio0.60.61.21.11.00.80.50.7-0.70.6-0.70.51.0
Novelty place preference0.50.51.11.10.90.70.40.6-0.70.5-0.60.50.9
Time in novel zone, NPP test0.50.50.91.00.90.70.50.6-0.70.6-0.60.50.9
Total zone transitions, NPP test1.31.92.5-0.7-1.4-1.5-1.6-1.41.3-1.41.4-1.4-1.4
Total locomotion distance, NPP test1.01.41.7-0.2-1.2-1.2-1.3-1.21.1-1.21.2-1.3-1.2
Locomotion velocity, NPP test1.52.12.8-0.3-1.5-1.5-1.6-1.51.4-1.51.6-1.7-1.5
Pavlov. Cond. lever latency0.30.40.60.70.50.70.80.6-0.60.6-0.60.80.5
Pavlov. Cond. magazine entry latency0.40.51.8-1.3-0.5-0.7-0.7-0.60.6-0.60.6-0.4-0.5
Pavlov. Cond. change in total contacts0.40.40.6-0.20.70.50.70.7-0.60.7-0.70.80.7
Pavlov. Cond. index score0.10.21.0-1.0-0.1-0.3-0.4-0.30.2-0.30.3-0.2-0.1
Pavlov. Cond. latency score0.10.10.8-0.90.0-0.1-0.2-0.10.1-0.10.1-0.10.0
Pavlov. Cond. lever contacts0.20.30.5-0.7-0.4-0.5-0.6-0.50.4-0.50.5-0.5-0.4
Pavlov. Cond. magazine entry number0.81.01.91.40.81.11.20.9-0.91.0-1.00.80.8
Pavlov. Cond. intertrial magazine entries0.10.10.20.4-0.4-0.4-0.1-0.30.4-0.30.3-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.9-0.9-0.1-0.2-0.3-0.20.2-0.20.2-0.2-0.1
Pavlov. Cond. response bias1.01.22.1-1.4-1.0-1.2-1.2-1.11.1-1.11.1-0.9-0.9
Bone: apparent density0.91.52.7-1.6-1.4-1.3-1.2-1.11.2-1.01.1-1.0-1.4
Bone surface0.00.10.6-0.80.0-0.2-0.3-0.0-0.00.00.0-0.00.0
Bone volume0.10.11.0-1.0-0.1-0.10.00.0-0.00.1-0.10.1-0.1
Bone: connectivity density0.71.11.7-1.2-1.1-1.2-1.3-1.01.0-0.90.9-0.9-1.1
Bone: cortical apparent density0.10.10.6-0.8-0.4-0.20.2-0.10.2-0.10.1-0.0-0.4
Bone: cortical area0.60.91.3-0.71.20.90.70.9-1.00.8-0.90.91.1
Bone: cortical porosity0.10.10.60.70.30.0-0.10.1-0.10.1-0.10.00.3
Bone: cortical porosity0.10.10.40.60.20.1-0.00.1-0.10.1-0.10.00.2
Bone: cortical thickness0.10.10.8-0.9-0.0-0.1-0.1-0.20.1-0.20.2-0.2-0.1
Bone: cortical thickness0.00.00.10.20.00.20.30.1-0.10.1-0.10.20.0
Bone: cortical tissue density0.10.10.4-0.6-0.3-0.10.2-0.00.10.00.00.0-0.3
Bone: elastic displacement0.00.00.1-0.1-0.2-0.3-0.3-0.20.3-0.20.2-0.2-0.2
Bone: elastic work0.00.10.1-0.20.30.20.20.2-0.20.2-0.20.30.3
Bone: endosteal estimation3.47.28.91.12.82.72.62.8-2.82.8-2.83.02.9
Bone: endosteal perimeter2.04.25.90.52.42.01.72.2-2.22.1-2.12.12.4
Bone: final force4.37.18.70.52.82.72.62.8-2.82.8-2.82.92.8
Bone: final moment3.76.28.00.22.62.52.52.6-2.62.6-2.62.82.6
Bone: marrow area3.57.49.21.12.92.72.62.9-2.92.9-2.93.02.9
Bone: maximum diameter0.61.21.8-0.81.41.00.71.1-1.21.0-1.11.11.4
Bone: maximum force1.72.93.9-0.31.81.71.61.8-1.81.8-1.82.01.8
Bone: maximum moment1.32.33.2-0.51.61.51.51.6-1.61.5-1.61.81.6
Bone: minimum diameter1.83.45.2-0.12.31.91.41.9-2.01.8-1.81.92.3
Bone: periosteal estimation2.45.06.30.32.52.22.02.4-2.42.3-2.32.42.5
Bone: periosteal perimeter1.21.92.9-0.31.71.41.11.4-1.51.4-1.41.51.7
Bone: post-yield work0.30.41.1-1.00.60.50.40.5-0.50.5-0.50.60.6
Bone: stiffness1.32.12.9-0.31.41.41.41.6-1.51.6-1.61.71.5
Bone: tissue strength0.00.00.1-0.3-0.1-0.00.1-0.00.0-0.00.0-0.0-0.1
Bone: trabecular number1.52.33.7-1.9-1.6-1.5-1.5-1.41.5-1.31.4-1.4-1.6
Bone: trabecular spacing2.22.93.11.71.71.71.81.7-1.71.7-1.71.61.7
Bone: trabecular thickness0.20.31.0-1.00.10.40.70.5-0.30.5-0.50.60.1
Bone: trabecular tissue density0.00.00.1-0.3-0.2-0.10.30.00.10.1-0.00.1-0.2
Breakpoint value in progressive ratio session0.30.30.4-0.2-0.5-0.5-0.4-0.60.6-0.60.6-0.6-0.6
Distance traveled before self-admin1.21.34.32.11.21.01.10.9-1.00.9-0.90.71.1
Distance traveled after self-admin0.10.10.80.90.30.20.20.2-0.20.2-0.2-0.10.2
Delta time in closed arm before/after self-admin3.43.310.73.31.91.81.21.5-1.61.4-1.41.22.0
Delta time in open arm before/after self-admin1.11.02.7-1.6-1.0-1.0-0.8-0.90.9-0.90.9-0.7-1.0
Diff in mean of infusions in LGA sessions0.80.91.0-0.7-0.9-1.0-0.9-1.01.0-1.01.0-0.8-1.0
Extinction: sum of active levers before priming0.40.42.91.70.1-0.1-0.4-0.30.2-0.50.4-0.60.2
Active lever presses in extinction session 60.20.21.6-1.20.30.00.30.2-0.10.1-0.20.50.2
Delta distance traveled before/after self-admin0.70.81.5-1.2-0.8-0.8-0.9-0.80.8-0.80.8-0.8-0.8
Delta ambulatory time before/after self-admin1.11.21.8-1.3-1.2-1.0-1.1-1.01.0-1.01.0-1.1-1.1
Time in closed arm before self-admin0.20.20.60.1-0.2-0.4-0.8-0.50.3-0.50.5-0.8-0.2
Time in closed arm after self-admin0.40.41.21.10.90.60.40.5-0.60.4-0.40.30.9
Time in open arm before self-admin0.91.01.9-1.2-1.4-0.9-0.5-0.81.0-0.70.8-0.7-1.4
Time in open arm after self-admin3.13.45.2-2.1-2.2-1.8-1.6-1.71.9-1.61.6-1.5-2.3
Sum of active levers in priming session hrs 5-60.60.61.71.3-0.3-0.6-0.8-0.70.6-0.70.7-0.8-0.4
Time to tail flick, vehicle, before self-admin1.41.42.8-1.70.51.11.31.2-1.01.3-1.31.60.5
Time to tail flick, vehicle, after self-admin0.10.10.70.80.1-0.2-0.5-0.20.1-0.20.2-0.30.1
Time to tail flick, test, before self-admin0.10.10.2-0.5-0.4-0.4-0.2-0.40.5-0.30.4-0.3-0.4
Time to tail flick, test, after self-admin1.81.814.1-3.8-1.2-0.6-0.1-0.30.5-0.20.2-0.1-1.3
Delta time to tail flick, vehicle, before/after SA0.60.60.80.4-0.4-0.9-0.9-0.80.7-0.90.9-0.9-0.4
Delta time to tail flick, test, before/after SA1.21.12.4-1.60.40.91.11.1-1.01.1-1.11.20.4
Ambulatory time before self-admin0.50.61.81.30.80.60.80.6-0.60.6-0.60.50.7
Ambulatory time after self-admin0.30.30.7-0.1-0.6-0.5-0.5-0.60.6-0.50.5-0.8-0.7
Total heroin consumption0.91.11.60.2-1.3-1.0-0.8-1.11.2-1.01.0-0.9-1.3
Area under the delay curve1.21.31.5-0.91.11.21.21.2-1.11.2-1.21.21.1
Delay disc. indifference point, 0s delay0.70.81.91.01.30.90.40.7-0.80.6-0.60.61.4
Delay disc. indifference point, 16s delay0.90.97.5-2.7-0.00.20.70.3-0.20.3-0.40.5-0.0
Delay disc. indifference point, 2s delay0.00.00.20.40.10.0-0.3-0.0-0.1-0.10.1-0.20.2
Delay disc. indifference point, 24s delay2.72.63.2-1.41.51.51.81.7-1.61.7-1.71.81.4
Delay disc. indifference point, 4s delay1.51.61.90.21.31.41.31.3-1.31.3-1.31.41.3
Delay disc. indifference point, 8s delay1.91.92.70.11.31.51.71.5-1.41.5-1.51.61.3
Delay discount exponential model param1.01.01.21.1-0.9-1.0-1.1-1.01.0-1.01.0-1.1-0.9
Delay discount hyperbolic model param0.70.70.90.9-0.7-0.9-0.9-0.90.8-0.90.9-0.9-0.8
Fecal boli incidents, locomotor time 10.10.10.7-0.8-0.0-0.00.00.1-0.00.1-0.10.2-0.1
Change in fecal boli incidents, locomotor task2.72.614.23.81.81.20.50.9-1.20.7-0.80.41.7
Time >=10cm from walls, locomotor time 12.52.55.82.41.71.61.21.4-1.61.4-1.41.21.6
Bouts of movement, locomotor time 10.30.40.7-0.8-0.6-0.7-0.6-0.60.7-0.60.6-0.5-0.7
Total resting periods, locomotor time 10.20.20.9-0.9-0.4-0.4-0.3-0.30.4-0.30.3-0.2-0.5
Rest time, locomotor task time 10.20.20.60.60.80.30.20.4-0.40.4-0.40.30.6
Distance moved, locomotor task time 10.10.10.3-0.20.10.40.50.3-0.20.2-0.30.30.3
Vertical activity count, locomotor time 10.50.50.8-0.10.60.80.90.7-0.70.7-0.70.80.7
Time >=10cm from walls, locomotor time 29.49.914.73.83.63.22.63.0-3.32.9-2.92.63.4
Bouts of movement, locomotor time 20.30.32.5-1.6-0.40.00.30.2-0.00.1-0.20.3-0.4
Total resting periods, locomotor time 20.30.31.7-1.3-0.6-0.4-0.2-0.20.3-0.30.2-0.2-0.6
Rest time, locomotor task time 20.10.10.30.60.40.1-0.10.1-0.20.1-0.1-0.00.5
Distance moved, locomotor task time 21.92.23.01.21.41.61.71.5-1.51.5-1.51.51.4
Vertical activity count, locomotor time 21.01.11.30.51.01.11.11.1-1.21.1-1.11.00.8
Weight adjusted by age2.73.08.93.02.01.71.01.5-1.81.4-1.40.91.8
Seeking ratio, delayed vs. immediate footshock0.70.85.3-2.3-0.9-0.50.1-0.30.5-0.20.20.0-0.9
Locomotion in novel chamber0.20.20.4-0.2-0.4-0.5-0.3-0.50.4-0.50.5-0.6-0.4
Locomotion in novel chamber post-restriction1.82.23.30.31.41.41.81.6-1.61.6-1.61.51.4
Progressive ratio2.02.43.8-1.10.91.51.91.6-1.51.7-1.71.91.0
Food seeking constrained by brief footshock0.50.65.2-2.3-0.3-0.2-0.3-0.20.2-0.20.2-0.1-0.3
Seeking ratio, punishment vs. effort1.11.32.70.6-0.5-1.1-1.6-1.21.0-1.31.3-1.5-0.5
Run reversals in cocaine runway, females0.30.32.0-1.4-0.10.20.50.3-0.10.3-0.30.7-0.1
Run reversals in cocaine runway, males1.11.17.3-2.7-1.2-0.40.1-0.30.5-0.10.1-0.0-1.3
Latency to leave start box in cocaine runway0.60.63.21.80.6-0.2-0.9-0.30.1-0.50.4-0.80.7
Latency to leave start box in cocaine runway, F0.20.30.70.80.6-0.2-0.7-0.30.1-0.50.4-0.50.5
Latency to leave start box in cocaine runway, M0.30.32.61.60.30.2-0.30.0-0.2-0.0-0.0-0.30.5
Cd content in liver0.70.81.30.40.70.81.11.0-0.91.0-1.01.10.7
Co content in liver2.52.93.21.61.81.81.61.7-1.71.7-1.71.61.8
Cu content in liver3.03.74.4-0.9-2.0-1.9-2.1-2.01.9-2.02.0-2.1-2.0
Fe content in liver3.33.94.80.41.92.12.12.2-2.12.2-2.22.21.9
K content in liver1.01.01.9-0.0-0.8-1.1-1.4-1.11.0-1.11.1-1.2-0.8
Mg content in liver1.91.93.30.1-1.1-1.4-1.8-1.51.4-1.51.5-1.6-1.1
Mn content in liver0.00.10.20.2-0.0-0.2-0.5-0.20.1-0.20.2-0.3-0.0
Na content in liver0.30.30.50.7-0.4-0.6-0.6-0.50.4-0.40.4-0.7-0.4
Rb content in liver0.20.30.50.70.60.50.50.5-0.50.4-0.50.40.6
Se content in liver2.53.04.6-0.3-1.6-1.7-2.1-1.81.7-1.81.9-2.0-1.6
Sr content in liver0.00.00.10.3-0.0-0.0-0.1-0.10.1-0.10.1-0.1-0.0
Zn content in liver2.32.53.71.61.91.71.11.5-1.61.3-1.41.51.9