Hub : Genes

Nedd4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000088391 0.07 0.05 2.0e-06 0.05 0.04 0.04 0.04 2.5e-06 5.3e-05 4.6e-05 1.2e-05
2 Adipose alternative polyA ENSRNOT00000101505 0.07 0.05 1.3e-06 0.06 0.04 0.04 0.05 9.3e-07 2.1e-05 1.6e-05 2.4e-06
3 Adipose gene expression ENSRNOG00000058898 0.25 0.11 5.9e-15 0.13 0.12 0.11 0.12 7.6e-14 2.1e-13 1.5e-12 1.5e-13
4 Brain gene expression ENSRNOG00000058898 0.1 0.06 5.3e-09 0.09 0.09 0.1 0.09 2.8e-08 4.5e-09 3.5e-09 5.7e-09
5 LHb gene expression ENSRNOG00000058898 0.26 0.16 8.7e-03 0.04 0.04 0.03 0.04 4.0e-02 3.5e-02 7.6e-02 3.8e-02
6 Liver gene expression ENSRNOG00000058898 0.07 0.05 8.8e-07 0.03 0.03 0.04 0.03 1.2e-04 1.5e-04 6.2e-05 1.1e-04
7 NAcc gene expression ENSRNOG00000058898 0.08 0.04 9.6e-07 0.09 0.09 0.09 0.09 3.1e-07 2.6e-07 2.4e-07 1.7e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail4.614.923.74.0-4.03.74.6-1.5-3.44.9
BMI without tail0.40.82.7-0.20.2-0.11.50.50.41.6
Body weight3.916.624.04.3-4.34.14.5-1.8-3.84.9
Epididymis fat weight0.30.81.6-0.80.8-1.1-0.70.81.2-0.7
Glucose0.10.20.6-0.40.4-0.4-0.00.80.20.5
Heart weight1.82.63.91.5-1.51.72.0-1.5-1.41.7
Left kidney weight1.64.67.42.2-2.22.22.50.0-2.12.7
Right kidney weight1.13.35.81.7-1.71.82.2-0.7-1.72.4
Tail length1.23.85.8-2.42.4-2.2-1.31.42.2-1.2
Length with tail0.31.21.91.0-1.01.21.2-0.3-1.11.4
Length without tail6.714.620.44.5-4.54.33.1-1.9-4.33.3
Liver weight, left0.40.61.8-0.60.6-1.0-0.11.30.50.5
Liver weight, right0.20.41.3-0.10.1-0.20.90.80.11.1
Parametrial fat weight1.52.94.5-1.41.4-2.1-2.11.51.8-1.3
Retroperitoneal fat weight0.10.20.4-0.40.4-0.5-0.50.40.6-0.1
Intraocular pressure0.10.20.4-0.60.6-0.20.10.10.40.3
Extensor digitorum longus weight3.714.929.73.7-3.73.65.1-0.3-2.85.4
Soleus weight6.117.739.03.7-3.73.95.90.1-2.96.2
Tibialis anterior weight4.616.034.93.7-3.73.75.11.4-2.95.9
Tibia length1.44.06.62.6-2.61.91.3-1.4-2.51.0
Number of licking bursts3.33.95.8-2.42.4-1.9-2.00.71.9-1.9
Food consumed during 24 hour testing period0.30.31.70.2-0.20.20.21.3-0.50.4
Times rat made contact with spout0.20.20.5-0.10.1-0.6-0.70.40.0-0.4
Mean time between licks in bursts0.10.20.6-0.40.4-0.4-0.8-0.40.1-0.4
Mean num. licks in bursts2.42.95.32.3-2.31.31.4-0.2-1.91.5
Std. dev. time between licks in bursts0.60.71.60.3-0.30.91.2-1.2-0.61.1
Water consumed over 24 hours0.10.10.20.2-0.2-0.0-0.4-0.1-0.4-0.4
Indifference point 0 sec0.10.20.8-0.30.3-0.3-0.10.90.3-0.2
Indifference point AUC0.60.71.2-0.80.8-1.0-0.3-1.01.1-0.5
Indifference point function ln k0.50.71.50.8-0.80.80.41.0-1.20.9
Indifference point function log k0.50.71.50.8-0.80.80.41.0-1.20.9
Delay discounting total patch changes 0 sec0.10.21.0-0.10.1-0.20.01.00.2-0.1
Delay discounting total patch changes 12 sec0.20.30.8-0.40.4-0.5-0.6-0.00.9-0.6
Delay discounting total patch changes 18 sec0.00.00.1-0.10.1-0.2-0.10.10.2-0.2
Delay discounting total patch changes 24 sec1.11.42.6-1.41.4-1.3-0.80.71.6-0.7
Delay discounting total patch changes 6 sec0.30.41.2-0.80.8-0.70.0-0.11.1-0.2
Delay discounting time to switch 0 sec0.10.20.70.1-0.10.3-0.4-0.40.0-0.8
Delay discounting water rate 0 sec0.60.92.10.9-0.90.51.20.7-0.81.5
Delay discounting water rate 12 sec0.60.83.6-0.10.1-0.10.71.90.21.3
Delay discounting water rate 18 sec0.10.20.40.4-0.4-0.00.10.7-0.20.5
Delay discounting water rate 24 sec1.01.42.7-1.21.2-1.6-1.11.01.2-0.6
Delay discounting water rate 6 sec0.10.20.6-0.20.2-0.4-0.00.80.20.7
Locomotor activity3.55.57.62.6-2.62.32.80.1-2.02.7
Locomotor testing distance1.83.04.51.9-1.91.62.00.4-1.62.1
Locomotor testing rearing0.40.71.70.8-0.80.41.10.1-0.61.3
Light reinforcement 12.24.06.42.0-2.01.62.5-1.3-1.82.5
Light reinforcement 20.30.40.90.7-0.70.2-0.90.0-1.0-0.5
Reaction time number correct0.40.51.80.3-0.30.51.20.5-0.11.3
Reaction time mean minus median0.91.11.8-0.90.9-1.0-1.30.91.0-1.3
Reaction time mean minus median AUC2.32.94.5-1.51.5-1.7-2.11.41.7-2.0
Reaction time num false alarms1.21.62.6-1.61.6-1.3-1.00.91.2-1.0
Reaction time num false alarms AUC1.41.92.9-1.71.7-1.4-0.91.51.4-0.9
Reaction time trials correct on left0.40.51.80.3-0.30.51.20.5-0.11.3
Reaction time trials on left0.40.51.70.2-0.20.41.10.60.01.3
Reaction time mean1.72.45.1-1.21.2-1.4-2.30.51.1-2.2
Reaction time mean AUC1.92.55.2-1.31.3-1.4-2.20.51.2-2.3
Median of all reaction times1.52.14.9-1.11.1-1.3-2.20.20.9-2.2
Reaction time omissions0.50.71.5-1.21.2-0.8-0.20.80.8-0.3
Reaction time false alarm rate1.52.12.6-1.61.6-1.6-1.51.01.2-1.6
Reaction time premature initiation rate0.10.10.50.1-0.10.10.50.3-0.10.7
Reaction time premature initiations0.40.61.80.4-0.40.51.20.4-0.21.3
Std. dev. reaction times1.82.44.3-1.41.4-1.5-2.10.91.4-2.0
Reaction time trials completed0.40.51.70.2-0.20.41.10.60.01.3
Reaction time trials AUC0.30.51.60.2-0.20.41.10.50.01.3
Social response proportion2.42.63.41.7-1.71.91.6-1.2-1.81.3
Social responses0.10.20.60.3-0.30.40.8-0.2-0.30.4
Social time0.20.21.20.0-0.0-0.2-0.31.10.4-0.2
Conditioned locomotion2.63.04.92.2-2.21.61.5-1.8-1.70.9
Cocaine response after cond. corrected2.02.33.01.6-1.61.71.51.1-1.21.7
Cocaine response after cond. not corrected1.71.92.61.5-1.51.61.30.9-1.21.4
Cocaine response before conditioning0.20.31.2-0.30.3-0.3-0.3-1.1-0.1-0.5
Saline control response0.60.72.2-0.40.4-0.9-0.81.50.7-0.9
Condit. Reinf. active minus inactive responses1.92.44.31.4-1.41.42.1-0.4-1.32.1
Condit. Reinf. active-inactive response ratio2.42.53.01.7-1.71.71.7-0.3-1.61.7
Condit. Reinf. active responses1.82.54.31.4-1.41.42.1-1.2-1.52.0
Condit. Reinf. inactive responses0.20.31.4-0.40.4-0.30.2-1.20.10.2
Condit. Reinf. lever presses0.30.41.10.7-0.70.30.0-0.5-1.1-0.1
Condit. Reinf. lever reinforcers received1.82.63.81.5-1.51.52.0-1.3-1.61.8
Pavlov. Cond. lever latency0.20.31.7-0.30.3-0.1-0.01.30.50.2
Pavlov. Cond. magazine entry latency1.41.63.2-1.01.0-1.4-1.8-0.40.7-1.7
Pavlov. Cond. change in total contacts0.10.20.5-0.00.0-0.3-0.5-0.70.1-0.5
Pavlov. Cond. index score0.30.30.6-0.30.3-0.6-0.7-0.80.2-0.8
Pavlov. Cond. latency score0.20.20.5-0.20.2-0.5-0.7-0.60.0-0.7
Pavlov. Cond. lever contacts0.20.31.50.4-0.40.00.1-1.2-0.5-0.0
Pavlov. Cond. magazine entry number1.41.73.01.2-1.21.31.70.3-1.01.7
Pavlov. Cond. intertrial magazine entries0.20.21.3-0.20.20.30.11.10.30.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.40.4-0.6-0.8-0.90.1-0.9
Pavlov. Cond. response bias0.40.53.00.1-0.1-0.2-0.2-1.7-0.3-0.5
Conditioned reinforcement - actives0.30.30.4-0.70.7-0.6-0.30.60.7-0.3
Conditioned reinforcement - inactives0.10.10.5-0.20.2-0.3-0.40.70.3-0.2
Conditioned locomotion1.01.22.71.0-1.01.30.7-1.6-1.10.5
Intermittent access intake day 1-15 change3.63.64.2-2.02.0-2.0-1.72.12.1-1.4
Intermittent access intake escalation4.14.04.6-2.12.1-2.1-1.82.02.1-1.6
Intermittent access intake escalation 20.80.81.6-0.80.8-0.9-0.81.30.9-0.7
Intermitt. access day 1 inactive lever presses0.20.20.70.1-0.10.1-0.80.5-0.4-0.6
Intermitt. access day 15 inactive lever presses0.60.71.10.8-0.80.90.6-1.1-0.90.5
Intermitt. access escalation Index2.42.12.81.5-1.51.51.7-1.0-1.31.7
Intermittent access day 1 total infusions0.20.20.7-0.10.1-0.0-0.80.6-0.0-0.8
Intermittent access day 15 total infusions2.02.23.0-1.41.4-1.3-1.71.51.4-1.6
Intermittent access terminal intake (last 3 days)0.40.41.0-0.40.4-0.4-0.90.60.4-1.0
Intermittent access total infusions1.92.13.7-1.21.2-1.1-1.81.91.1-1.5
Intermittent access day 1 locomotion0.50.51.1-0.60.6-0.5-1.10.40.4-1.1
Intermittent access day 15 total locomotion0.10.20.50.2-0.20.3-0.70.2-0.3-0.5
Intermittent access total locomotion0.20.30.8-0.40.4-0.2-0.70.90.2-0.3
Intermittent access standard deviation1.21.32.3-0.90.9-0.8-1.51.31.1-1.4
Cocaine induced anxiety0.10.20.7-0.20.2-0.1-0.2-0.80.4-0.4
Post-drug Anxiety1.92.12.8-1.61.6-1.5-1.2-0.51.7-1.6
Baseline Anxiety1.31.42.2-1.51.5-1.3-1.00.41.2-0.9
Lifetime Intake1.61.82.8-1.21.2-1.0-1.71.71.2-1.4
Incentive Sensitization - Responses1.71.72.41.4-1.41.41.5-0.4-1.11.3
Incentive Sensitization - Breakpoint1.41.42.11.3-1.31.21.5-0.4-1.01.2
Progressive ratio test 1 active lever presses0.50.51.6-0.60.6-0.5-0.61.30.6-0.4
Progressive ratio test 1 breakpoint0.40.41.0-0.50.5-0.5-0.81.00.5-0.6
Progressive ratio test 1 inactive lever presses3.33.55.2-1.71.7-1.7-2.32.21.5-1.9
Progressive ratio test 2 active lever presses0.10.10.60.2-0.20.10.20.80.20.2
Progressive ratio test 2 breakpoint0.20.21.00.2-0.20.20.21.00.10.3
Progressive ratio test 2 inactive lever presses0.10.10.50.1-0.10.3-0.70.4-0.0-0.5
Total sessions with >9 infusions1.71.84.0-1.31.3-1.0-1.22.01.3-1.1
Short access day 1 total inactive lever presses1.01.15.7-0.60.6-0.3-0.82.40.7-0.5
Short access day 10 total inactive lever presses1.01.11.8-0.90.9-0.9-1.41.30.8-1.1
Short access day 1 total infusions0.50.61.2-0.60.6-0.3-0.81.10.8-0.8
Short access day 10 total infusions1.01.12.1-0.80.8-0.6-1.41.30.9-1.3
Short access total infusions2.02.23.7-1.31.3-1.1-1.91.71.3-1.7
Short access day 1 locomotion0.10.10.3-0.30.3-0.1-0.20.60.4-0.2
Short access day 10 total locomotion0.20.21.3-0.10.10.0-0.61.10.0-0.1
Short access total locomotion0.80.81.8-0.70.7-0.5-1.41.00.6-1.1
Compulsive drug intake0.30.30.70.5-0.50.60.40.1-0.80.4
One hour access (0.3 mA shock)0.20.30.70.6-0.60.80.20.2-0.70.1
One hour access (shock baseline)0.10.10.2-0.10.10.0-0.40.20.1-0.5
Number of responses in last shaping day0.10.10.2-0.40.4-0.3-0.40.50.3-0.2
Context. condit. distance diff. score0.30.30.70.6-0.60.70.1-0.8-0.70.1
Locomotion velocity, session 10.50.52.3-0.50.5-0.60.01.50.50.3
Locomotion distance, session 11.01.22.3-1.01.0-1.5-1.20.81.2-1.0
Locomotion velocity, session 20.10.10.20.1-0.1-0.30.40.20.4-0.1
Locomotion distance, session 20.20.41.0-0.50.5-0.9-0.10.41.0-0.1
Locomotion velocity, session 32.73.25.5-1.71.7-1.8-1.51.92.3-1.3
Locomotion distance, session 32.62.93.9-1.81.8-1.7-2.00.31.8-1.8
Stereotopy head waving bouts, day 30.20.30.50.6-0.60.20.40.7-0.40.6
Stereotopy head waving duration, day 30.60.71.11.0-1.00.50.80.9-0.70.9
Locomotion velocity, session 70.60.71.6-0.60.6-0.8-1.10.20.8-1.3
Locomotion distance, session 72.22.93.8-1.81.8-1.6-1.70.71.9-1.9
Stereotopy head waving bouts, day 70.20.21.0-0.10.1-0.50.11.00.60.4
Stereotopy head waving duration, day 70.40.42.0-0.30.3-0.50.11.40.80.3
Locomotion velocity, session 80.20.21.0-0.20.2-0.40.21.00.7-0.0
Locomotion distance, session 80.40.60.9-0.80.8-0.9-0.6-0.21.0-0.7
Degree of sensitization distance0.10.10.2-0.20.2-0.1-0.20.30.4-0.5
Degree of sensitization stereotypy0.10.10.50.0-0.0-0.30.30.70.40.4
Condit. Reinf. active minus inactive responses0.70.84.70.3-0.30.30.6-2.2-0.60.4
Condit. Reinf. active-inactive response ratio1.31.43.61.0-1.01.20.6-1.9-1.50.4
Condit. Reinf. active responses0.40.51.5-0.70.7-0.60.3-1.20.60.1
Condit. Reinf. inactive responses2.83.36.3-2.12.1-2.3-0.81.12.5-0.8
Incentive salience index mean1.21.55.90.8-0.80.71.1-2.4-0.90.6
Condit. Reinf. lever presses0.81.03.80.7-0.70.61.1-2.0-0.70.4
Time in familiar zone, hab. session 10.70.61.30.7-0.70.80.8-1.1-0.70.5
Time in novel zone, hab. session 10.50.51.1-0.60.6-0.5-0.81.00.6-0.7
Total zone transitions, hab. session 11.42.03.1-1.31.3-1.7-1.40.91.8-1.2
Total locomotion distance, hab. session 10.91.32.6-1.11.1-1.6-1.00.61.4-0.7
Locomotion velocity, hab. session 10.71.02.2-1.01.0-1.5-0.80.71.1-0.5
Time in familiar zone, hab. session 20.70.81.2-1.11.1-0.9-0.80.70.9-0.6
Time in novel zone, hab. session 20.70.71.51.2-1.20.90.5-0.2-1.00.4
Total zone transitions, hab. session 20.20.20.9-0.10.1-0.40.3-1.00.40.4
Total locomotion distance, hab. session 20.30.41.70.1-0.1-0.20.7-1.30.00.9
Locomotion velocity, hab. session 20.30.41.80.2-0.2-0.00.6-1.3-0.10.8
Novel to familiar place preference ratio1.81.92.31.5-1.51.41.5-0.8-1.21.5
Novelty place preference2.22.22.81.7-1.71.61.6-0.8-1.41.5
Time in novel zone, NPP test2.22.33.01.7-1.71.61.5-0.6-1.41.6
Total zone transitions, NPP test0.10.20.5-0.40.4-0.70.0-0.40.50.2
Total locomotion distance, NPP test0.30.51.0-0.80.8-1.0-0.20.21.00.1
Locomotion velocity, NPP test0.71.12.0-1.21.2-1.4-0.50.31.4-0.3
Pavlov. Cond. lever latency0.30.42.1-0.30.30.0-0.71.5-0.1-0.3
Pavlov. Cond. magazine entry latency3.64.718.31.7-1.71.61.6-4.3-1.70.6
Pavlov. Cond. change in total contacts1.41.55.91.1-1.10.71.0-2.4-0.90.6
Pavlov. Cond. index score1.01.37.90.5-0.50.30.6-2.8-0.3-0.1
Pavlov. Cond. latency score0.70.95.90.4-0.40.10.6-2.4-0.1-0.1
Pavlov. Cond. lever contacts0.50.63.40.5-0.50.30.7-1.8-0.30.2
Pavlov. Cond. magazine entry number2.32.913.2-1.31.3-1.1-1.13.61.1-0.1
Pavlov. Cond. intertrial magazine entries2.83.44.7-2.22.2-2.1-1.31.82.0-0.9
Pavlov. Cond. lever-magazine prob. diff.1.11.48.30.6-0.60.40.8-2.9-0.50.1
Pavlov. Cond. response bias2.53.112.31.4-1.41.21.4-3.5-1.30.5
Bone: apparent density0.10.10.30.4-0.40.30.1-0.6-0.40.0
Bone surface0.10.20.40.4-0.40.60.60.1-0.20.6
Bone volume0.40.60.90.9-0.90.90.8-0.2-0.70.7
Bone: connectivity density1.42.12.6-1.51.5-1.6-1.60.51.6-1.5
Bone: cortical apparent density0.30.41.0-0.60.6-0.4-1.00.10.4-0.9
Bone: cortical area1.92.94.72.2-2.22.11.2-0.1-2.00.9
Bone: cortical porosity0.40.40.80.7-0.70.80.2-0.9-0.8-0.2
Bone: cortical porosity0.50.61.60.7-0.70.80.2-1.3-0.8-0.3
Bone: cortical thickness0.50.91.61.3-1.31.1-0.3-0.3-1.1-0.4
Bone: cortical thickness0.20.20.40.5-0.50.6-0.40.2-0.6-0.6
Bone: cortical tissue density0.30.41.0-0.60.6-0.4-1.00.10.4-0.9
Bone: elastic displacement0.20.20.40.3-0.30.20.4-0.5-0.50.6
Bone: elastic work1.11.52.41.2-1.21.11.0-1.4-1.51.0
Bone: endosteal estimation1.12.34.81.3-1.31.52.20.3-1.32.0
Bone: endosteal perimeter3.36.911.22.7-2.72.73.3-0.6-2.43.1
Bone: final force1.82.93.91.9-1.92.01.8-0.6-1.81.4
Bone: final moment1.93.14.42.1-2.12.01.7-0.6-2.01.3
Bone: marrow area1.22.65.21.5-1.51.62.30.3-1.42.1
Bone: maximum diameter2.44.46.12.3-2.32.52.20.2-2.12.1
Bone: maximum force2.23.84.92.2-2.22.22.2-0.8-2.01.7
Bone: maximum moment2.34.05.32.3-2.32.32.1-0.8-2.11.6
Bone: minimum diameter2.34.36.22.5-2.52.31.8-1.4-2.41.2
Bone: periosteal estimation1.83.74.92.1-2.12.22.20.1-1.91.9
Bone: periosteal perimeter2.03.44.91.9-1.92.12.20.1-1.72.0
Bone: post-yield work0.10.10.40.0-0.00.20.7-0.20.20.6
Bone: stiffness0.40.61.70.5-0.50.70.91.3-0.00.8
Bone: tissue strength0.40.41.00.0-0.0-0.7-1.00.00.2-1.0
Bone: trabecular number0.20.30.6-0.50.5-0.5-0.6-0.30.5-0.7
Bone: trabecular spacing0.10.10.2-0.20.2-0.3-0.40.10.4-0.4
Bone: trabecular thickness0.50.61.01.0-1.01.00.30.3-1.00.4
Bone: trabecular tissue density4.56.39.52.6-2.63.12.51.1-2.32.9
Breakpoint value in progressive ratio session0.00.00.20.0-0.00.20.2-0.40.00.2
Distance traveled before self-admin0.10.10.20.4-0.40.50.3-0.1-0.20.3
Distance traveled after self-admin0.70.71.50.8-0.80.70.81.2-0.60.8
Delta time in closed arm before/after self-admin0.60.61.50.9-0.90.60.6-0.4-1.20.6
Delta time in open arm before/after self-admin3.23.14.1-1.81.8-1.7-1.81.42.0-1.7
Diff in mean of infusions in LGA sessions1.41.62.41.1-1.11.21.5-1.5-1.21.1
Extinction: sum of active levers before priming1.81.82.7-1.31.3-1.1-1.71.31.3-1.4
Active lever presses in extinction session 60.20.20.2-0.50.5-0.4-0.40.40.5-0.4
Delta distance traveled before/after self-admin0.60.62.30.5-0.50.30.61.5-0.50.8
Delta ambulatory time before/after self-admin0.60.61.90.7-0.70.50.41.4-0.70.7
Time in closed arm before self-admin0.20.31.10.4-0.40.60.2-1.0-0.30.0
Time in closed arm after self-admin0.10.10.20.3-0.30.30.2-0.2-0.50.3
Time in open arm before self-admin0.90.91.31.0-1.00.91.00.5-1.01.1
Time in open arm after self-admin0.50.51.7-0.50.5-0.5-0.81.30.7-0.6
Sum of active levers in priming session hrs 5-60.10.10.4-0.30.3-0.1-0.20.60.4-0.3
Time to tail flick, vehicle, before self-admin1.31.32.5-1.61.6-1.3-0.5-0.51.3-0.5
Time to tail flick, vehicle, after self-admin0.40.41.00.7-0.70.70.50.2-1.00.5
Time to tail flick, test, before self-admin0.80.83.90.4-0.40.50.6-2.0-0.60.3
Time to tail flick, test, after self-admin2.42.53.8-1.61.6-1.5-2.01.11.4-1.7
Delta time to tail flick, vehicle, before/after SA1.31.22.51.4-1.41.30.40.2-1.60.4
Delta time to tail flick, test, before/after SA1.51.34.2-0.70.7-0.8-1.42.00.7-0.9
Ambulatory time before self-admin0.00.00.1-0.20.20.1-0.1-0.10.2-0.3
Ambulatory time after self-admin0.60.61.90.7-0.70.60.51.4-0.60.5
Total heroin consumption0.20.20.6-0.10.1-0.00.50.70.70.4
Area under the delay curve1.61.72.61.4-1.41.31.1-1.6-1.30.9
Delay disc. indifference point, 0s delay0.30.31.5-0.40.4-0.4-0.1-1.20.2-0.3
Delay disc. indifference point, 16s delay1.81.82.71.5-1.51.40.8-1.5-1.70.6
Delay disc. indifference point, 2s delay0.00.00.1-0.20.2-0.2-0.30.00.1-0.3
Delay disc. indifference point, 24s delay0.20.20.40.5-0.50.40.3-0.6-0.50.1
Delay disc. indifference point, 4s delay0.70.82.30.8-0.80.70.6-1.5-0.90.4
Delay disc. indifference point, 8s delay0.80.91.40.9-0.90.81.2-1.0-0.80.9
Delay discount exponential model param1.31.41.9-1.21.2-1.1-1.11.41.2-0.8
Delay discount hyperbolic model param0.90.91.5-1.01.0-0.9-0.81.21.0-0.6
Fecal boli incidents, locomotor time 10.40.41.30.7-0.70.40.2-1.2-0.40.2
Change in fecal boli incidents, locomotor task0.60.62.20.5-0.50.40.21.5-0.90.5
Time >=10cm from walls, locomotor time 10.90.91.20.9-0.91.11.1-0.8-1.00.8
Bouts of movement, locomotor time 10.10.10.10.2-0.20.10.3-0.2-0.20.3
Total resting periods, locomotor time 10.00.00.00.1-0.1-0.00.1-0.1-0.10.1
Rest time, locomotor task time 10.30.30.50.7-0.70.4-0.3-0.3-0.7-0.0
Distance moved, locomotor task time 10.91.01.8-1.31.3-0.9-0.30.51.3-0.6
Vertical activity count, locomotor time 10.10.10.3-0.50.5-0.10.4-0.30.4-0.1
Time >=10cm from walls, locomotor time 20.20.20.40.5-0.50.40.4-0.5-0.60.5
Bouts of movement, locomotor time 20.10.20.2-0.30.3-0.50.40.30.50.4
Total resting periods, locomotor time 20.20.20.4-0.40.4-0.60.30.50.60.4
Rest time, locomotor task time 20.10.10.40.2-0.2-0.1-0.60.0-0.4-0.5
Distance moved, locomotor task time 21.01.22.4-1.41.4-0.9-0.30.81.5-0.4
Vertical activity count, locomotor time 21.31.42.0-1.41.4-1.1-0.90.81.4-1.2
Weight adjusted by age1.21.44.60.7-0.70.81.60.7-0.52.1
Seeking ratio, delayed vs. immediate footshock0.30.30.90.3-0.30.31.00.1-0.20.9
Locomotion in novel chamber0.20.20.80.1-0.10.1-0.90.2-0.4-0.8
Locomotion in novel chamber post-restriction0.10.10.6-0.00.00.20.3-0.8-0.20.1
Progressive ratio1.41.65.01.2-1.20.91.0-2.2-1.20.2
Food seeking constrained by brief footshock0.80.92.0-1.01.0-1.1-0.41.41.0-0.0
Seeking ratio, punishment vs. effort1.51.97.3-1.11.1-1.0-0.22.71.30.7
Run reversals in cocaine runway, females0.10.10.6-0.20.2-0.3-0.20.80.1-0.0
Run reversals in cocaine runway, males1.00.92.2-1.11.1-1.0-0.30.91.5-0.4
Latency to leave start box in cocaine runway0.70.71.90.7-0.70.71.1-0.1-0.61.4
Latency to leave start box in cocaine runway, F0.10.10.3-0.30.3-0.30.30.50.50.3
Latency to leave start box in cocaine runway, M2.72.64.21.6-1.61.71.7-0.9-1.52.0
Cd content in liver0.30.31.3-0.10.10.10.7-1.10.20.5
Co content in liver1.72.04.51.4-1.41.21.0-2.1-1.31.0
Cu content in liver1.51.82.41.3-1.31.51.5-1.2-1.21.3
Fe content in liver2.32.84.3-1.61.6-1.7-1.21.42.1-1.8
K content in liver1.21.21.71.2-1.21.31.0-0.2-0.91.3
Mg content in liver2.93.04.41.8-1.81.82.0-0.6-1.52.1
Mn content in liver2.32.74.32.0-2.02.11.0-0.7-2.01.0
Na content in liver0.20.20.40.4-0.40.40.70.6-0.20.7
Rb content in liver0.40.41.40.4-0.40.20.71.20.50.8
Se content in liver0.50.61.3-0.60.6-0.6-0.80.80.8-1.1
Sr content in liver0.10.10.6-0.20.2-0.2-0.0-0.80.1-0.1
Zn content in liver1.61.83.81.3-1.31.20.6-2.0-1.60.8