Hub : Genes

Tcf19

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000058288 0.09 0.05 5.2e-12 0.1 0.1 0.11 0.1 2.4e-11 7.6e-11 8.4e-12 3.0e-11
2 BLA gene expression ENSRNOG00000058288 0.29 0.1 8.3e-14 0.24 0.21 0.2 0.22 6.1e-13 2.3e-11 3.6e-11 4.2e-12
3 Brain gene expression ENSRNOG00000058288 0.23 0.08 0.0e+00 0.14 0.19 0.2 0.2 2.8e-13 1.9e-17 7.1e-18 5.2e-18
4 IL gene expression ENSRNOG00000058288 0.32 0.13 3.4e-06 0.12 0.22 0.22 0.17 1.0e-03 4.1e-06 4.5e-06 5.9e-05
5 Liver gene expression ENSRNOG00000058288 0.09 0.05 6.3e-07 0.04 0.05 0.04 0.05 5.4e-05 1.5e-06 5.3e-05 2.9e-06
6 NAcc gene expression ENSRNOG00000058288 0.05 0.03 9.4e-04 0 0.01 -0 -0 1.8e-01 9.0e-02 5.8e-01 4.6e-01
7 OFC gene expression ENSRNOG00000058288 0.37 0.16 1.3e-05 0.2 0.17 0.15 0.17 1.4e-05 6.3e-05 1.9e-04 6.0e-05
8 PL gene expression ENSRNOG00000058288 0.33 0.09 0.0e+00 0.23 0.14 0.32 0.19 1.0e-17 1.2e-10 2.9e-25 1.3e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.34.38.4-2.22.42.41.70.91.82.91.6
BMI without tail3.37.09.9-3.12.82.82.61.72.53.02.4
Body weight6.126.037.4-4.45.45.95.03.94.96.14.8
Epididymis fat weight1.53.510.2-3.01.0-0.5-1.6-3.2-1.21.4-1.5
Glucose1.62.47.41.6-0.60.91.62.71.5-0.61.8
Heart weight0.50.61.6-1.20.30.50.90.71.10.40.8
Left kidney weight3.49.614.4-3.13.53.52.92.12.83.82.9
Right kidney weight3.39.513.5-2.42.83.63.22.63.03.73.1
Tail length6.419.525.2-3.13.74.95.04.74.54.24.8
Length with tail5.319.425.8-3.04.25.14.74.34.34.74.6
Length without tail3.47.510.7-1.62.83.32.72.52.53.22.9
Liver weight, left1.21.93.1-0.31.01.61.61.61.81.11.4
Liver weight, right5.08.311.4-1.52.63.23.23.42.72.73.3
Parametrial fat weight1.22.35.5-1.42.01.91.00.50.72.31.2
Retroperitoneal fat weight0.20.81.4-1.10.71.00.80.41.01.20.7
Intraocular pressure1.11.52.41.6-1.3-1.0-1.3-1.1-1.1-0.9-1.4
Extensor digitorum longus weight0.20.92.00.10.40.91.11.41.20.31.2
Soleus weight2.16.115.30.30.92.33.03.92.90.83.1
Tibialis anterior weight0.20.51.5-0.3-0.1-0.6-0.9-1.2-0.8-0.1-0.9
Tibia length4.312.015.3-2.02.93.83.93.83.93.13.9
Number of licking bursts0.20.20.70.7-0.4-0.00.40.80.2-0.50.4
Food consumed during 24 hour testing period1.31.62.50.21.11.61.41.61.31.11.3
Times rat made contact with spout2.93.45.50.7-1.4-1.9-2.1-2.4-2.0-1.4-2.3
Mean time between licks in bursts0.91.23.80.9-0.00.81.32.01.0-0.11.3
Mean num. licks in bursts1.01.23.7-0.3-0.3-0.9-1.3-1.9-1.1-0.2-1.5
Std. dev. time between licks in bursts1.72.05.60.20.31.21.82.41.60.21.8
Water consumed over 24 hours0.10.10.30.20.10.20.40.60.30.00.4
Indifference point 0 sec0.30.51.8-1.30.6-0.1-0.2-1.00.30.4-0.6
Indifference point AUC1.82.13.3-1.41.81.81.31.00.81.81.5
Indifference point function ln k0.10.20.50.7-0.6-0.50.00.40.0-0.7-0.0
Indifference point function log k0.10.20.50.7-0.6-0.50.00.40.0-0.7-0.0
Delay discounting total patch changes 0 sec0.40.62.4-1.50.7-0.1-0.2-1.10.20.6-0.6
Delay discounting total patch changes 12 sec0.40.62.4-1.60.90.1-0.1-0.9-0.00.8-0.3
Delay discounting total patch changes 18 sec1.11.44.5-0.50.2-0.7-1.4-2.1-1.20.1-1.6
Delay discounting total patch changes 24 sec2.53.26.80.1-0.7-1.8-2.1-2.6-2.0-1.2-2.2
Delay discounting total patch changes 6 sec0.50.72.0-1.40.8-0.3-0.5-1.4-0.20.4-0.8
Delay discounting time to switch 0 sec0.50.81.60.3-0.5-1.1-1.1-1.3-0.7-0.6-1.2
Delay discounting water rate 0 sec0.30.40.6-0.70.80.80.60.50.50.70.6
Delay discounting water rate 12 sec0.50.71.10.3-0.5-0.9-0.9-1.1-1.1-0.8-1.0
Delay discounting water rate 18 sec0.10.20.3-0.10.00.50.50.30.40.50.4
Delay discounting water rate 24 sec0.81.12.4-1.21.21.30.80.40.31.51.0
Delay discounting water rate 6 sec0.10.20.3-0.0-0.1-0.4-0.5-0.6-0.5-0.2-0.5
Locomotor activity2.64.15.5-1.11.82.12.42.32.31.72.2
Locomotor testing distance0.61.01.8-0.60.90.91.21.11.30.61.0
Locomotor testing rearing1.11.82.7-0.51.31.41.51.51.71.11.3
Light reinforcement 10.10.10.3-0.20.2-0.3-0.4-0.5-0.3-0.0-0.4
Light reinforcement 20.60.81.40.00.81.20.91.00.81.00.8
Reaction time number correct0.20.31.0-1.00.2-0.4-0.4-1.00.00.3-0.5
Reaction time mean minus median0.81.02.91.7-0.20.90.91.70.40.21.0
Reaction time mean minus median AUC0.50.72.61.6-0.50.50.51.30.1-0.20.6
Reaction time num false alarms0.30.50.8-0.50.60.90.70.80.30.70.9
Reaction time num false alarms AUC0.60.91.4-0.90.91.01.00.90.50.91.2
Reaction time trials correct on left0.20.31.0-1.00.2-0.4-0.4-1.00.00.3-0.5
Reaction time trials on left0.20.31.0-1.00.2-0.3-0.3-0.90.10.3-0.5
Reaction time mean0.91.34.72.2-0.70.50.71.70.4-0.50.8
Reaction time mean AUC0.91.24.52.1-0.80.60.71.70.5-0.50.8
Median of all reaction times0.70.93.51.9-0.70.40.61.40.4-0.60.6
Reaction time omissions0.50.72.31.5-0.30.50.61.40.4-0.20.7
Reaction time false alarm rate0.60.92.0-0.30.51.11.11.40.50.61.4
Reaction time premature initiation rate1.01.42.3-1.31.51.21.10.81.01.21.1
Reaction time premature initiations1.11.63.9-2.01.71.00.90.31.11.40.9
Std. dev. reaction times1.01.44.31.4-0.11.01.32.10.80.11.3
Reaction time trials completed0.20.31.0-1.00.2-0.3-0.3-0.90.10.3-0.5
Reaction time trials AUC0.20.30.8-0.90.2-0.4-0.4-0.90.00.2-0.5
Social response proportion0.80.92.3-0.80.00.51.21.21.50.21.1
Social responses0.60.82.0-1.40.20.51.00.81.20.51.0
Social time1.21.54.50.70.41.11.42.10.90.21.7
Conditioned locomotion0.91.11.6-0.20.91.31.21.21.20.91.1
Cocaine response after cond. corrected0.60.71.31.1-0.9-0.8-0.8-0.4-0.8-1.0-0.5
Cocaine response after cond. not corrected0.50.51.20.00.30.70.81.10.80.31.0
Cocaine response before conditioning6.88.39.8-2.62.73.03.12.63.02.93.0
Saline control response0.70.92.7-1.71.20.60.3-0.70.61.4-0.1
Condit. Reinf. active minus inactive responses1.61.92.5-1.61.41.41.41.11.41.41.4
Condit. Reinf. active-inactive response ratio3.63.74.4-1.81.92.02.11.81.91.82.1
Condit. Reinf. active responses0.10.10.2-0.5-0.10.10.30.10.50.10.1
Condit. Reinf. inactive responses1.31.62.60.9-1.6-1.5-1.2-1.1-0.7-1.3-1.5
Condit. Reinf. lever presses0.30.40.60.0-0.8-0.8-0.5-0.6-0.4-0.7-0.6
Condit. Reinf. lever reinforcers received0.00.00.1-0.4-0.2-0.10.20.10.4-0.10.1
Pavlov. Cond. lever latency0.30.40.6-0.10.60.70.70.80.50.50.8
Pavlov. Cond. magazine entry latency0.50.61.0-0.41.01.00.70.70.30.90.9
Pavlov. Cond. change in total contacts0.10.20.5-0.70.50.2-0.1-0.4-0.20.5-0.1
Pavlov. Cond. index score0.00.00.0-0.20.10.1-0.1-0.2-0.20.2-0.0
Pavlov. Cond. latency score0.00.10.2-0.50.30.20.1-0.1-0.00.30.1
Pavlov. Cond. lever contacts0.40.61.5-0.1-0.4-0.7-0.9-1.2-0.8-0.3-1.0
Pavlov. Cond. magazine entry number0.20.20.50.1-0.7-0.6-0.3-0.20.0-0.7-0.3
Pavlov. Cond. intertrial magazine entries0.50.61.51.1-1.2-0.6-0.00.50.0-1.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.20.10.1-0.0-0.2-0.10.2-0.0
Pavlov. Cond. response bias0.20.30.60.3-0.3-0.4-0.7-0.8-0.8-0.2-0.7
Conditioned reinforcement - actives0.40.40.9-0.80.90.40.50.40.50.40.6
Conditioned reinforcement - inactives0.60.72.0-1.31.40.60.3-0.20.21.10.3
Conditioned locomotion0.10.10.2-0.10.30.20.40.40.5-0.00.4
Intermittent access intake day 1-15 change0.20.20.5-0.40.60.60.1-0.2-0.20.70.1
Intermittent access intake escalation0.10.10.50.20.30.70.30.3-0.00.40.3
Intermittent access intake escalation 20.60.61.51.0-0.20.90.71.20.20.20.8
Intermitt. access day 1 inactive lever presses0.91.02.0-0.30.60.91.21.41.20.71.2
Intermitt. access day 15 inactive lever presses2.62.85.7-1.92.41.61.40.91.32.11.3
Intermitt. access escalation Index2.52.24.11.6-1.6-1.7-1.3-0.8-1.2-2.0-1.4
Intermittent access day 1 total infusions0.70.81.30.7-0.6-1.1-1.0-0.8-1.0-0.9-0.9
Intermittent access day 15 total infusions0.30.30.60.5-0.1-0.6-0.7-0.7-0.8-0.4-0.6
Intermittent access terminal intake (last 3 days)0.00.00.1-0.30.3-0.1-0.1-0.2-0.1-0.0-0.0
Intermittent access total infusions0.10.10.30.00.1-0.4-0.4-0.5-0.4-0.2-0.4
Intermittent access day 1 locomotion0.20.20.40.7-0.7-0.3-0.00.10.2-0.5-0.2
Intermittent access day 15 total locomotion0.90.91.6-0.10.71.31.11.01.00.91.0
Intermittent access total locomotion0.50.51.10.20.51.00.70.70.70.90.7
Intermittent access standard deviation1.71.84.0-1.91.41.41.00.31.02.00.9
Cocaine induced anxiety1.31.56.02.4-1.1-0.9-0.70.1-0.6-1.7-0.8
Post-drug Anxiety0.30.31.01.0-0.3-0.30.00.50.3-0.9-0.1
Baseline Anxiety0.30.32.0-1.40.2-0.20.2-0.20.50.30.2
Lifetime Intake0.00.00.1-0.10.3-0.3-0.2-0.2-0.1-0.2-0.1
Incentive Sensitization - Responses1.01.01.80.9-0.7-1.1-1.2-1.1-1.3-0.6-1.1
Incentive Sensitization - Breakpoint1.21.22.01.1-0.9-1.1-1.3-1.1-1.4-0.7-1.1
Progressive ratio test 1 active lever presses0.20.20.60.2-0.5-0.6-0.3-0.2-0.2-0.8-0.3
Progressive ratio test 1 breakpoint0.20.20.60.1-0.4-0.6-0.3-0.2-0.1-0.8-0.2
Progressive ratio test 1 inactive lever presses0.20.20.6-0.00.1-0.5-0.6-0.8-0.50.1-0.6
Progressive ratio test 2 active lever presses1.01.01.40.8-0.6-1.2-1.1-1.0-1.1-0.9-1.1
Progressive ratio test 2 breakpoint1.71.82.31.1-1.1-1.5-1.5-1.4-1.5-1.2-1.4
Progressive ratio test 2 inactive lever presses0.30.31.4-0.31.20.50.50.40.20.60.5
Total sessions with >9 infusions0.00.00.1-0.10.2-0.00.10.10.1-0.10.3
Short access day 1 total inactive lever presses1.01.12.80.40.70.91.21.71.10.51.3
Short access day 10 total inactive lever presses0.20.20.50.40.20.50.40.70.30.30.4
Short access day 1 total infusions0.10.10.60.1-0.3-0.7-0.10.00.0-0.8-0.1
Short access day 10 total infusions0.00.10.1-0.40.3-0.00.20.20.2-0.10.3
Short access total infusions0.10.10.4-0.60.4-0.00.30.30.3-0.00.4
Short access day 1 locomotion2.22.33.91.9-1.8-1.8-1.3-0.7-1.1-2.0-1.2
Short access day 10 total locomotion1.41.63.4-0.6-0.40.91.61.71.80.31.5
Short access total locomotion0.30.30.80.0-0.5-0.10.50.70.9-0.50.5
Compulsive drug intake2.12.14.81.6-1.9-1.6-1.1-0.3-1.0-2.2-0.9
One hour access (0.3 mA shock)1.01.12.11.4-0.6-1.0-1.0-0.6-1.3-1.2-0.8
One hour access (shock baseline)0.30.41.3-0.11.10.80.40.30.30.70.4
Number of responses in last shaping day0.90.91.4-0.91.20.41.01.11.00.41.1
Context. condit. distance diff. score2.93.510.13.2-2.6-1.5-0.90.4-0.8-2.6-0.8
Locomotion velocity, session 10.10.10.20.3-0.4-0.20.00.3-0.1-0.40.0
Locomotion distance, session 11.11.52.60.6-0.8-1.2-1.4-1.3-1.6-1.1-1.2
Locomotion velocity, session 20.00.00.10.20.00.10.10.4-0.2-0.10.3
Locomotion distance, session 20.70.91.61.2-0.8-0.8-1.0-0.6-1.3-1.0-0.8
Locomotion velocity, session 30.20.20.5-0.60.2-0.2-0.4-0.7-0.30.1-0.5
Locomotion distance, session 31.92.12.61.5-1.3-1.5-1.5-1.2-1.6-1.4-1.5
Stereotopy head waving bouts, day 32.42.93.8-1.01.61.92.01.91.81.51.9
Stereotopy head waving duration, day 32.02.43.2-1.51.31.51.81.51.81.31.6
Locomotion velocity, session 74.65.18.83.0-2.4-2.2-2.2-1.4-2.3-2.4-2.0
Locomotion distance, session 75.26.68.62.7-2.5-2.6-2.7-2.0-2.9-2.7-2.4
Stereotopy head waving bouts, day 71.51.73.0-1.71.71.41.10.70.71.61.2
Stereotopy head waving duration, day 72.42.94.6-1.82.11.91.51.11.22.01.6
Locomotion velocity, session 81.41.75.30.80.21.11.52.31.20.01.6
Locomotion distance, session 82.23.310.73.3-2.2-1.4-1.10.2-1.3-2.3-0.8
Degree of sensitization distance0.20.20.50.5-0.7-0.20.20.60.2-0.60.3
Degree of sensitization stereotypy0.80.81.8-1.21.40.90.60.30.11.20.8
Condit. Reinf. active minus inactive responses0.70.81.50.6-1.0-1.0-0.8-0.6-0.8-1.2-0.8
Condit. Reinf. active-inactive response ratio0.10.10.4-0.6-0.1-0.3-0.3-0.5-0.2-0.2-0.3
Condit. Reinf. active responses1.31.62.11.2-1.4-1.4-1.3-1.0-1.2-1.5-1.2
Condit. Reinf. inactive responses3.13.64.41.9-1.7-1.9-2.1-1.8-2.1-1.6-2.0
Incentive salience index mean1.01.23.41.8-1.4-0.9-0.60.1-0.7-1.5-0.5
Condit. Reinf. lever presses1.62.28.32.9-1.8-1.0-0.60.4-0.8-1.9-0.5
Time in familiar zone, hab. session 15.45.17.70.9-2.0-2.4-2.6-2.8-2.4-1.8-2.6
Time in novel zone, hab. session 13.63.55.3-0.91.41.92.22.32.31.32.1
Total zone transitions, hab. session 10.60.91.40.7-1.2-1.0-0.9-0.6-0.9-1.2-0.8
Total locomotion distance, hab. session 10.71.01.50.9-1.1-1.1-1.0-0.7-1.0-1.2-0.8
Locomotion velocity, hab. session 10.40.60.90.5-0.7-0.9-0.8-0.7-0.9-1.0-0.6
Time in familiar zone, hab. session 20.50.51.10.0-0.7-0.7-0.9-1.0-0.7-0.4-0.8
Time in novel zone, hab. session 20.40.40.5-0.50.70.60.70.60.70.60.4
Total zone transitions, hab. session 20.10.20.40.2-0.2-0.4-0.5-0.4-0.7-0.3-0.3
Total locomotion distance, hab. session 21.52.02.41.5-1.4-1.5-1.5-1.1-1.5-1.6-1.3
Locomotion velocity, hab. session 21.62.12.91.6-1.5-1.5-1.5-1.0-1.6-1.7-1.2
Novel to familiar place preference ratio0.10.10.3-0.1-0.0-0.3-0.3-0.4-0.5-0.3-0.3
Novelty place preference0.00.00.1-0.30.2-0.1-0.1-0.1-0.3-0.0-0.1
Time in novel zone, NPP test0.10.10.2-0.50.40.10.20.0-0.10.20.1
Total zone transitions, NPP test1.31.82.41.6-1.5-1.3-1.3-0.8-1.4-1.5-1.2
Total locomotion distance, NPP test1.72.43.11.7-1.4-1.5-1.6-1.2-1.6-1.6-1.5
Locomotion velocity, NPP test2.73.94.82.2-1.9-2.0-2.1-1.5-2.0-2.2-1.9
Pavlov. Cond. lever latency0.70.93.7-1.90.60.1-0.3-1.20.30.9-0.6
Pavlov. Cond. magazine entry latency0.40.51.61.3-0.9-0.20.31.00.0-0.80.4
Pavlov. Cond. change in total contacts1.01.02.2-0.10.71.11.21.50.60.71.5
Pavlov. Cond. index score0.70.93.41.8-0.8-0.10.41.3-0.1-1.00.6
Pavlov. Cond. latency score0.70.82.91.7-0.50.20.51.5-0.1-0.70.9
Pavlov. Cond. lever contacts0.70.92.71.6-0.10.40.71.60.1-0.51.0
Pavlov. Cond. magazine entry number0.50.71.7-1.21.30.70.1-0.50.11.30.0
Pavlov. Cond. intertrial magazine entries1.31.63.20.4-1.0-1.2-1.5-1.8-1.1-0.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.70.93.51.9-1.0-0.20.21.2-0.2-1.00.5
Pavlov. Cond. response bias0.70.82.81.7-1.1-0.30.21.00.0-1.10.3
Bone: apparent density2.54.25.32.0-1.6-2.0-2.3-2.0-2.3-1.8-2.3
Bone surface0.10.30.40.30.40.60.60.70.40.40.6
Bone volume0.00.10.10.30.30.1-0.2-0.3-0.30.2-0.2
Bone: connectivity density2.84.36.72.6-2.2-2.1-2.0-1.5-1.8-2.2-2.1
Bone: cortical apparent density0.30.41.3-0.90.4-0.1-0.5-1.1-0.30.6-0.6
Bone: cortical area1.42.23.4-1.21.81.71.31.01.01.81.5
Bone: cortical porosity0.40.42.4-1.50.60.20.2-0.20.10.70.3
Bone: cortical porosity0.80.81.8-1.40.80.80.90.70.70.91.0
Bone: cortical thickness1.01.63.8-1.92.00.90.0-0.9-0.31.90.3
Bone: cortical thickness0.50.61.8-1.00.4-0.2-0.7-1.4-0.60.5-0.7
Bone: cortical tissue density0.30.41.0-0.90.4-0.1-0.4-1.0-0.20.5-0.5
Bone: elastic displacement0.30.30.7-0.70.4-0.2-0.5-0.8-0.60.3-0.5
Bone: elastic work0.91.22.8-1.21.71.20.70.30.41.50.8
Bone: endosteal estimation5.812.518.8-1.72.43.64.24.34.32.64.0
Bone: endosteal perimeter2.14.310.30.20.51.92.63.22.60.62.5
Bone: final force3.35.410.1-2.53.22.61.80.91.53.12.0
Bone: final moment3.15.09.3-2.33.02.51.81.01.53.02.0
Bone: marrow area5.912.619.2-1.82.43.64.24.34.42.64.0
Bone: maximum diameter1.52.75.70.01.01.81.92.41.61.02.1
Bone: maximum force2.95.19.0-2.23.02.61.91.11.53.02.0
Bone: maximum moment2.84.98.4-2.12.92.61.91.21.62.92.0
Bone: minimum diameter2.24.17.9-0.21.12.12.42.82.41.12.5
Bone: periosteal estimation4.59.111.8-1.92.63.33.43.23.42.73.4
Bone: periosteal perimeter2.33.85.8-0.81.52.12.32.42.01.52.4
Bone: post-yield work0.70.92.20.7-0.10.81.11.51.30.20.9
Bone: stiffness0.50.71.7-0.91.21.00.50.00.41.30.6
Bone: tissue strength2.32.25.1-1.22.31.71.10.70.62.21.2
Bone: trabecular number3.35.17.32.2-1.7-2.1-2.5-2.3-2.7-1.8-2.5
Bone: trabecular spacing5.36.97.9-2.52.62.72.82.42.72.62.8
Bone: trabecular thickness2.12.53.21.6-1.3-1.5-1.8-1.6-1.8-1.3-1.8
Bone: trabecular tissue density1.41.93.9-2.01.81.31.10.70.81.61.3
Breakpoint value in progressive ratio session0.80.81.80.7-1.3-1.1-0.7-0.4-0.7-1.3-0.7
Distance traveled before self-admin0.30.30.70.80.10.60.50.80.6-0.30.5
Distance traveled after self-admin0.80.92.1-0.70.51.01.21.11.40.50.9
Delta time in closed arm before/after self-admin0.40.40.9-0.50.30.50.70.71.00.50.7
Delta time in open arm before/after self-admin0.10.10.2-0.1-0.2-0.1-0.3-0.5-0.30.1-0.3
Diff in mean of infusions in LGA sessions3.94.36.12.1-1.6-2.5-2.2-1.6-2.3-2.2-2.0
Extinction: sum of active levers before priming0.50.51.20.5-1.1-1.0-0.6-0.4-0.5-0.8-0.6
Active lever presses in extinction session 60.20.20.4-0.2-0.2-0.4-0.5-0.7-0.30.0-0.6
Delta distance traveled before/after self-admin1.11.23.3-1.81.10.91.00.41.01.30.7
Delta ambulatory time before/after self-admin0.70.81.6-1.30.90.70.90.71.00.80.7
Time in closed arm before self-admin0.00.00.1-0.20.3-0.00.0-0.00.1-0.2-0.0
Time in closed arm after self-admin0.40.41.0-0.81.00.50.3-0.00.21.00.4
Time in open arm before self-admin0.20.20.50.7-0.7-0.30.00.2-0.1-0.6-0.1
Time in open arm after self-admin0.40.41.30.6-1.1-0.7-0.3-0.2-0.2-0.9-0.6
Sum of active levers in priming session hrs 5-60.20.20.60.0-0.5-0.8-0.3-0.2-0.1-0.7-0.4
Time to tail flick, vehicle, before self-admin0.30.31.31.10.50.0-0.40.0-0.7-0.2-0.2
Time to tail flick, vehicle, after self-admin0.40.42.11.5-0.6-0.20.10.70.0-0.5-0.2
Time to tail flick, test, before self-admin0.20.20.50.10.7-0.2-0.5-0.6-0.7-0.1-0.4
Time to tail flick, test, after self-admin1.31.34.22.1-1.4-0.6-0.8-0.4-1.1-1.1-0.9
Delta time to tail flick, vehicle, before/after SA0.50.51.20.8-1.1-0.7-0.5-0.3-0.4-0.7-0.7
Delta time to tail flick, test, before/after SA1.41.23.01.6-1.7-0.8-0.9-0.7-0.8-1.0-0.9
Ambulatory time before self-admin0.10.10.40.7-0.10.30.10.2-0.0-0.10.0
Ambulatory time after self-admin0.50.51.1-0.50.40.80.90.91.10.30.6
Total heroin consumption0.00.00.30.3-0.50.0-0.1-0.0-0.0-0.1-0.2
Area under the delay curve0.91.02.0-1.41.10.90.80.50.41.30.9
Delay disc. indifference point, 0s delay0.50.51.0-0.10.70.80.81.00.50.61.0
Delay disc. indifference point, 16s delay0.50.51.6-1.30.30.0-0.3-0.8-0.61.0-0.2
Delay disc. indifference point, 2s delay2.52.84.3-1.82.11.51.71.51.51.41.8
Delay disc. indifference point, 24s delay0.40.42.0-1.40.30.30.3-0.10.40.60.4
Delay disc. indifference point, 4s delay2.72.83.5-1.61.41.91.81.51.61.71.9
Delay disc. indifference point, 8s delay0.10.10.2-0.40.10.10.20.1-0.10.40.2
Delay discount exponential model param0.91.02.41.6-1.1-0.9-0.8-0.5-0.5-1.3-0.9
Delay discount hyperbolic model param1.21.32.71.6-1.2-1.0-1.0-0.7-0.7-1.4-1.1
Fecal boli incidents, locomotor time 10.40.51.30.5-0.7-0.8-0.6-0.5-0.2-1.1-0.7
Change in fecal boli incidents, locomotor task1.21.11.6-1.01.20.81.11.20.91.01.3
Time >=10cm from walls, locomotor time 12.22.23.6-0.41.11.51.71.81.91.31.5
Bouts of movement, locomotor time 10.91.03.01.7-1.6-0.7-0.6-0.2-0.7-1.0-0.7
Total resting periods, locomotor time 10.50.62.11.5-1.3-0.3-0.20.2-0.4-0.5-0.3
Rest time, locomotor task time 10.40.41.00.30.20.60.81.00.90.20.5
Distance moved, locomotor task time 10.30.30.9-0.90.70.50.2-0.10.10.60.3
Vertical activity count, locomotor time 10.10.10.5-0.70.50.4-0.0-0.30.10.20.1
Time >=10cm from walls, locomotor time 21.01.12.6-0.60.80.81.21.31.60.31.1
Bouts of movement, locomotor time 20.91.01.5-0.50.81.21.21.21.00.81.1
Total resting periods, locomotor time 21.01.02.1-0.20.61.11.31.41.10.61.2
Rest time, locomotor task time 21.01.23.31.5-0.20.91.11.81.00.11.0
Distance moved, locomotor task time 20.30.31.3-1.10.80.1-0.3-0.8-0.20.4-0.1
Vertical activity count, locomotor time 20.10.10.5-0.70.2-0.2-0.3-0.60.1-0.1-0.3
Weight adjusted by age4.85.47.8-2.22.42.22.62.12.81.92.4
Seeking ratio, delayed vs. immediate footshock0.60.71.3-1.11.00.70.80.40.70.80.8
Locomotion in novel chamber0.40.51.1-0.61.00.90.60.50.41.00.6
Locomotion in novel chamber post-restriction0.50.61.2-1.00.70.80.60.20.81.10.5
Progressive ratio3.43.96.4-2.52.52.21.70.81.72.31.5
Food seeking constrained by brief footshock0.00.00.0-0.20.1-0.2-0.1-0.20.0-0.2-0.1
Seeking ratio, punishment vs. effort2.63.25.42.0-2.2-2.1-1.5-0.8-1.4-2.3-1.4
Run reversals in cocaine runway, females0.30.31.0-0.2-0.4-0.4-0.7-1.0-0.60.0-0.7
Run reversals in cocaine runway, males1.41.32.80.30.91.41.31.70.90.91.3
Latency to leave start box in cocaine runway0.20.20.9-0.20.90.00.20.4-0.10.30.4
Latency to leave start box in cocaine runway, F0.10.20.40.60.1-0.5-0.30.1-0.5-0.5-0.1
Latency to leave start box in cocaine runway, M0.80.81.8-1.11.30.80.50.30.11.40.7
Cd content in liver0.20.20.40.00.40.3-0.3-0.6-0.40.6-0.3
Co content in liver0.80.93.4-1.81.10.60.4-0.30.71.10.4
Cu content in liver5.26.38.31.2-2.0-2.8-2.9-2.8-2.8-2.3-2.8
Fe content in liver0.30.41.1-1.10.80.3-0.1-0.60.00.8-0.2
K content in liver0.20.20.40.6-0.6-0.4-0.4-0.1-0.6-0.6-0.1
Mg content in liver1.31.33.31.8-1.6-0.9-0.20.7-0.4-1.8-0.0
Mn content in liver1.41.64.71.3-0.70.31.22.21.2-1.01.3
Na content in liver0.10.10.60.20.3-0.2-0.4-0.3-0.8-0.1-0.1
Rb content in liver0.70.92.21.5-1.2-0.9-0.8-0.4-0.6-1.1-0.8
Se content in liver0.60.72.21.1-0.70.10.71.50.4-0.90.9
Sr content in liver1.11.01.7-0.40.81.01.21.31.20.61.3
Zn content in liver0.10.10.3-0.00.10.00.30.50.4-0.40.5