AABR07063281.1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000057813 0.49 0.22 0.0e+00 0.4 0.4 0.4 0.4 2.4e-47 1.2e-47 5.9e-48 7.0e-48
2 Adipose mRNA stability ENSRNOG00000057813 0.18 0.14 1.7e-16 0.14 0.15 0.15 0.15 7.2e-16 6.4e-16 6.0e-16 5.1e-16
3 BLA gene expression ENSRNOG00000057813 0.22 0.15 1.3e-07 0.11 0.12 0.12 0.12 1.1e-06 4.8e-07 7.4e-07 7.0e-07
4 Brain gene expression ENSRNOG00000057813 0.37 0.19 0.0e+00 0.29 0.29 0.28 0.28 1.8e-27 1.2e-26 5.7e-26 2.9e-26
5 Brain mRNA stability ENSRNOG00000057813 0.03 0.03 5.8e-03 0.02 0.02 0.02 0.01 1.1e-02 9.5e-03 9.7e-03 1.5e-02
6 IL gene expression ENSRNOG00000057813 0.4 0.22 2.2e-06 0.14 0.12 0.14 0.14 2.6e-04 8.9e-04 2.7e-04 3.6e-04
7 LHb gene expression ENSRNOG00000057813 0.25 0.18 1.0e-04 0.17 0.16 0.15 0.16 9.5e-05 1.1e-04 2.0e-04 1.4e-04
8 LHb intron excision ratio chr6:25089154:25090053 0.14 0.12 8.1e-03 0.05 0.08 0.04 0.07 2.8e-02 5.5e-03 3.6e-02 1.1e-02
9 Liver gene expression ENSRNOG00000057813 0.2 0.17 8.7e-15 0.12 0.12 0.12 0.12 4.5e-13 2.2e-13 3.0e-13 1.2e-13
10 NAcc gene expression ENSRNOG00000057813 0.04 0.04 8.9e-04 0.03 0.04 0.04 0.04 1.4e-03 9.7e-04 1.1e-03 1.1e-03
11 NAcc intron excision ratio chr6:25089154:25090053 0.41 0.01 4.6e-03 0.01 0.01 0 0 8.9e-02 4.0e-02 1.2e-01 1.4e-01
12 PL gene expression ENSRNOG00000057813 0.09 0.09 2.1e-04 0.05 0.05 0.05 0.05 5.8e-05 6.8e-05 1.5e-04 6.3e-05
13 PL mRNA stability ENSRNOG00000057813 0.06 0.05 1.6e-04 0.06 0.05 0.06 0.06 1.7e-05 6.7e-05 3.4e-05 2.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.41.21.7-1.1-1.1-1.1-1.3-1.1-0.9-1.21.1-1.2-1.10.8-1.1-1.2
BMI without tail0.20.40.8-0.6-0.8-0.5-0.5-0.7-0.5-0.90.7-0.8-0.6-0.4-0.4-0.5
Body weight1.77.28.0-2.7-2.8-2.8-2.6-2.8-2.7-2.82.8-2.8-2.81.9-2.7-2.6
Epididymis fat weight14.132.835.5-5.8-5.9-5.9-5.5-5.9-5.9-5.96.0-5.8-5.94.2-5.9-5.5
Glucose0.20.30.6-0.6-0.7-0.5-0.6-0.6-0.5-0.80.6-0.7-0.6-0.2-0.5-0.3
Heart weight9.113.015.5-3.8-3.9-3.4-3.9-3.8-3.4-3.93.7-3.9-3.61.9-3.6-3.8
Left kidney weight0.00.10.4-0.10.0-0.2-0.2-0.0-0.20.00.10.1-0.10.6-0.2-0.4
Right kidney weight1.23.48.6-1.7-1.4-1.9-1.9-1.6-1.9-1.31.7-1.4-1.72.9-2.0-2.1
Tail length0.10.30.5-0.5-0.7-0.6-0.2-0.6-0.5-0.70.6-0.7-0.6-0.2-0.4-0.4
Length with tail1.45.05.7-2.2-2.3-2.4-2.0-2.3-2.3-2.32.3-2.3-2.31.7-2.3-2.2
Length without tail0.71.51.8-1.2-1.1-1.3-1.3-1.2-1.2-1.11.2-1.1-1.21.3-1.3-1.3
Liver weight, left1.21.92.5-1.4-1.5-1.3-1.4-1.4-1.4-1.51.4-1.5-1.40.8-1.4-1.6
Liver weight, right8.714.516.7-3.9-4.0-3.8-3.9-3.9-3.8-3.93.9-4.0-3.92.6-3.8-4.1
Parametrial fat weight5.611.014.1-3.3-3.4-3.3-3.5-3.3-3.2-3.33.3-3.4-3.32.6-3.3-3.8
Retroperitoneal fat weight20.768.473.3-8.5-8.5-8.4-8.2-8.5-8.5-8.48.5-8.5-8.56.0-8.6-8.1
Intraocular pressure5.57.815.5-2.7-2.3-3.0-2.9-2.5-2.9-2.22.7-2.3-2.83.9-3.0-2.8
Extensor digitorum longus weight4.317.318.74.34.34.24.34.34.24.2-4.34.34.3-2.94.24.0
Soleus weight4.212.215.43.63.93.43.43.73.53.8-3.73.93.6-1.53.43.0
Tibialis anterior weight3.411.813.13.53.63.53.43.63.63.5-3.63.63.5-2.33.53.1
Tibia length2.36.48.3-2.6-2.8-2.5-2.5-2.7-2.5-2.92.6-2.8-2.61.1-2.4-2.5
Number of licking bursts0.10.20.60.30.50.20.20.40.20.5-0.30.50.30.80.1-0.4
Food consumed during 24 hour testing period0.20.30.40.50.50.60.50.50.60.4-0.50.50.6-0.60.60.0
Times rat made contact with spout2.02.33.11.61.81.51.61.71.51.7-1.61.81.6-0.31.41.1
Mean time between licks in bursts2.53.53.9-1.9-1.8-1.9-2.0-1.9-1.9-1.81.9-1.8-1.91.7-1.9-2.0
Mean num. licks in bursts0.10.20.40.40.30.40.50.30.40.3-0.40.30.4-0.60.40.6
Std. dev. time between licks in bursts0.10.10.5-0.2-0.3-0.2-0.2-0.3-0.2-0.40.3-0.3-0.2-0.3-0.1-0.7
Water consumed over 24 hours1.61.92.21.51.41.51.51.51.51.4-1.51.41.5-0.91.40.8
Indifference point 0 sec0.40.60.9-0.8-0.8-0.8-0.7-0.8-0.8-0.80.8-0.8-0.80.7-0.9-0.6
Indifference point AUC2.52.95.81.71.41.91.71.61.91.3-1.61.31.7-2.42.01.5
Indifference point function ln k0.00.00.1-0.1-0.2-0.10.0-0.2-0.2-0.20.2-0.2-0.1-0.1-0.2-0.1
Indifference point function log k0.00.00.1-0.1-0.2-0.10.0-0.2-0.2-0.20.2-0.2-0.1-0.1-0.2-0.1
Delay discounting total patch changes 0 sec0.30.40.7-0.6-0.6-0.7-0.6-0.6-0.7-0.70.6-0.6-0.70.7-0.8-0.6
Delay discounting total patch changes 12 sec0.71.01.3-1.0-1.0-1.0-1.1-1.0-0.9-1.11.0-1.0-1.00.6-0.9-1.0
Delay discounting total patch changes 18 sec0.00.10.4-0.1-0.30.00.0-0.10.0-0.30.1-0.3-0.1-0.6-0.0-0.1
Delay discounting total patch changes 24 sec0.81.01.8-1.0-1.2-0.9-0.9-1.1-0.9-1.41.0-1.2-1.0-0.2-0.8-1.1
Delay discounting total patch changes 6 sec0.00.00.1-0.2-0.3-0.2-0.2-0.2-0.1-0.30.2-0.3-0.20.1-0.2-0.2
Delay discounting time to switch 0 sec0.10.21.9-0.00.3-0.2-0.30.1-0.30.30.00.3-0.11.4-0.20.0
Delay discounting water rate 0 sec0.10.21.90.1-0.40.20.5-0.10.2-0.40.0-0.40.0-1.40.1-0.1
Delay discounting water rate 12 sec1.62.42.8-1.6-1.6-1.6-1.5-1.6-1.6-1.71.6-1.6-1.61.1-1.5-1.6
Delay discounting water rate 18 sec0.60.81.0-1.0-1.0-0.9-0.8-1.0-1.0-1.01.0-1.0-0.90.4-0.9-0.9
Delay discounting water rate 24 sec2.02.83.4-1.6-1.5-1.9-1.5-1.7-1.8-1.51.7-1.5-1.71.8-1.8-1.6
Delay discounting water rate 6 sec1.31.92.5-1.4-1.4-1.4-1.4-1.4-1.3-1.51.4-1.4-1.40.7-1.3-1.6
Locomotor activity0.40.63.6-0.5-0.2-0.8-0.6-0.4-0.8-0.20.5-0.2-0.61.9-0.8-0.8
Locomotor testing distance0.20.31.00.40.70.20.20.50.20.7-0.40.70.41.00.20.3
Locomotor testing rearing0.71.12.71.11.00.91.31.00.91.0-1.01.11.0-0.70.91.7
Light reinforcement 14.07.38.62.72.82.92.42.82.92.7-2.82.82.9-2.12.82.3
Light reinforcement 23.74.85.92.22.22.41.82.32.42.2-2.32.22.3-1.92.41.8
Reaction time number correct0.50.71.00.91.00.90.80.90.90.9-0.91.00.9-0.40.90.6
Reaction time mean minus median0.00.00.1-0.1-0.1-0.10.1-0.1-0.1-0.20.1-0.1-0.1-0.3-0.10.2
Reaction time mean minus median AUC0.10.10.1-0.3-0.3-0.3-0.2-0.3-0.3-0.30.3-0.3-0.30.0-0.2-0.1
Reaction time num false alarms0.20.31.90.30.60.1-0.10.40.20.6-0.30.60.31.40.0-0.1
Reaction time num false alarms AUC0.30.42.20.40.80.20.00.60.30.8-0.50.80.41.50.1-0.1
Reaction time trials correct on left0.50.71.00.91.00.90.80.90.90.9-0.91.00.9-0.40.90.6
Reaction time trials on left0.60.81.00.91.00.90.81.01.00.9-1.01.00.9-0.40.90.6
Reaction time mean1.21.71.9-1.3-1.3-1.3-1.4-1.3-1.3-1.31.3-1.3-1.31.2-1.3-1.3
Reaction time mean AUC1.11.41.7-1.2-1.2-1.2-1.3-1.2-1.2-1.21.2-1.2-1.21.2-1.2-1.2
Median of all reaction times1.41.82.3-1.3-1.3-1.3-1.5-1.3-1.3-1.31.3-1.3-1.31.4-1.3-1.5
Reaction time omissions0.10.10.10.30.40.30.30.30.30.3-0.30.40.3-0.30.30.4
Reaction time false alarm rate0.20.32.6-0.20.2-0.3-0.40.0-0.30.20.10.2-0.11.6-0.4-0.5
Reaction time premature initiation rate0.20.30.4-0.5-0.4-0.5-0.5-0.5-0.6-0.50.5-0.4-0.50.5-0.5-0.5
Reaction time premature initiations0.00.00.10.00.2-0.00.00.1-0.00.1-0.00.20.00.3-0.0-0.2
Std. dev. reaction times0.30.50.6-0.7-0.8-0.7-0.6-0.8-0.7-0.80.7-0.8-0.70.2-0.7-0.6
Reaction time trials completed0.60.81.00.91.00.90.81.01.00.9-1.01.00.9-0.40.90.6
Reaction time trials AUC0.71.01.31.11.11.00.91.11.11.0-1.11.11.1-0.51.00.7
Social response proportion0.30.40.7-0.6-0.8-0.5-0.2-0.7-0.5-0.70.6-0.8-0.6-0.5-0.6-0.5
Social responses0.10.20.8-0.2-0.5-0.10.1-0.4-0.2-0.50.3-0.5-0.2-0.9-0.2-0.4
Social time0.81.03.6-0.8-1.4-0.4-0.2-1.0-0.5-1.30.8-1.4-0.7-1.9-0.4-0.6
Conditioned locomotion3.03.64.22.02.01.92.02.01.92.0-2.02.01.9-1.21.91.9
Cocaine response after cond. corrected1.01.11.81.11.31.00.91.21.01.2-1.11.31.10.11.00.6
Cocaine response after cond. not corrected2.02.23.21.61.81.41.31.61.41.8-1.61.81.5-0.11.41.0
Cocaine response before conditioning1.11.31.61.11.01.21.21.11.21.1-1.11.01.2-1.21.21.3
Saline control response0.71.02.11.00.81.11.10.91.00.8-1.00.81.0-1.41.10.8
Condit. Reinf. active minus inactive responses3.84.75.62.22.32.12.22.22.12.3-2.22.32.2-1.32.12.4
Condit. Reinf. active-inactive response ratio1.01.01.31.01.11.00.91.11.01.1-1.01.11.0-0.41.01.0
Condit. Reinf. active responses3.04.25.62.12.12.02.12.12.02.2-2.12.12.1-1.21.92.4
Condit. Reinf. inactive responses1.62.02.71.51.51.41.51.51.41.6-1.51.51.4-0.81.41.6
Condit. Reinf. lever presses1.92.73.31.71.81.61.71.71.61.8-1.71.81.7-0.81.61.5
Condit. Reinf. lever reinforcers received2.63.75.21.92.01.92.02.01.92.0-2.02.01.9-1.21.82.3
Pavlov. Cond. lever latency1.72.42.8-1.6-1.6-1.6-1.7-1.6-1.5-1.51.6-1.6-1.61.2-1.6-1.3
Pavlov. Cond. magazine entry latency0.40.51.90.60.40.80.70.50.70.3-0.60.30.6-1.40.70.5
Pavlov. Cond. change in total contacts0.60.91.11.01.00.91.11.00.91.0-1.01.01.0-0.51.00.7
Pavlov. Cond. index score1.11.52.01.21.11.31.41.21.31.0-1.21.11.2-1.41.31.0
Pavlov. Cond. latency score1.11.42.31.21.01.31.41.11.31.0-1.21.01.2-1.51.30.9
Pavlov. Cond. lever contacts0.81.21.41.21.21.11.21.21.11.2-1.11.21.1-0.51.10.8
Pavlov. Cond. magazine entry number0.20.20.7-0.4-0.2-0.5-0.5-0.3-0.5-0.20.4-0.2-0.40.9-0.5-0.3
Pavlov. Cond. intertrial magazine entries3.54.55.3-2.1-2.0-2.3-2.1-2.1-2.3-1.92.1-1.9-2.22.3-2.2-1.9
Pavlov. Cond. lever-magazine prob. diff.0.81.11.71.00.91.11.21.01.10.9-1.00.91.1-1.31.10.8
Pavlov. Cond. response bias1.62.32.51.61.61.51.61.61.51.5-1.61.61.6-1.01.61.2
Conditioned reinforcement - actives1.71.79.81.00.41.21.50.71.20.3-0.80.40.9-3.11.21.4
Conditioned reinforcement - inactives3.03.47.31.71.52.11.81.71.81.4-1.81.51.9-2.71.81.8
Conditioned locomotion0.91.110.50.2-0.50.51.2-0.10.3-0.7-0.1-0.40.2-3.20.41.1
Intermittent access intake day 1-15 change0.50.43.70.3-0.00.60.40.20.8-0.0-0.3-0.00.4-1.90.80.3
Intermittent access intake escalation0.30.33.30.1-0.30.40.2-0.10.5-0.3-0.0-0.30.1-1.80.50.1
Intermittent access intake escalation 20.40.42.4-0.4-0.80.0-0.5-0.50.1-0.70.4-0.8-0.3-1.60.1-0.6
Intermitt. access day 1 inactive lever presses0.20.21.60.2-0.00.60.30.20.30.1-0.3-0.00.4-1.20.30.4
Intermitt. access day 15 inactive lever presses9.09.928.42.82.23.63.02.73.32.1-2.92.13.1-5.33.33.1
Intermitt. access escalation Index0.20.20.8-0.4-0.5-0.1-0.4-0.5-0.0-0.60.4-0.6-0.3-0.9-0.0-0.4
Intermittent access day 1 total infusions5.25.97.02.42.32.62.42.42.42.2-2.52.32.5-2.62.42.4
Intermittent access day 15 total infusions2.73.08.31.61.31.91.61.51.91.2-1.61.31.7-2.91.91.6
Intermittent access terminal intake (last 3 days)2.32.57.51.41.11.81.51.31.71.1-1.41.11.5-2.71.71.5
Intermittent access total infusions2.22.44.41.51.31.61.71.41.51.2-1.51.31.5-2.11.51.7
Intermittent access day 1 locomotion2.22.22.51.51.51.61.51.61.51.5-1.61.61.6-1.11.51.4
Intermittent access day 15 total locomotion0.80.92.80.90.71.01.00.80.90.6-0.90.70.9-1.70.90.8
Intermittent access total locomotion0.40.41.70.60.40.70.80.50.50.2-0.50.40.6-1.30.50.7
Intermittent access standard deviation0.30.32.70.3-0.00.60.60.20.40.0-0.3-0.00.4-1.60.40.5
Cocaine induced anxiety0.60.63.80.60.20.90.60.50.90.2-0.60.20.7-2.00.90.6
Post-drug Anxiety0.70.71.6-0.9-0.8-0.7-1.2-0.8-0.7-0.80.8-0.8-0.80.5-0.7-1.3
Baseline Anxiety1.61.75.8-1.2-0.7-1.4-1.4-1.0-1.4-0.81.2-0.7-1.22.4-1.4-1.5
Lifetime Intake3.13.57.11.81.52.02.01.71.81.4-1.81.51.8-2.71.72.1
Incentive Sensitization - Responses0.10.10.2-0.3-0.4-0.1-0.2-0.3-0.1-0.40.3-0.4-0.2-0.5-0.1-0.3
Incentive Sensitization - Breakpoint0.20.20.4-0.5-0.6-0.2-0.4-0.5-0.2-0.60.5-0.6-0.4-0.5-0.2-0.5
Progressive ratio test 1 active lever presses1.71.87.71.10.81.41.51.01.10.6-1.10.81.2-2.81.11.6
Progressive ratio test 1 breakpoint1.51.56.71.00.71.31.40.91.10.5-1.00.71.1-2.61.01.5
Progressive ratio test 1 inactive lever presses4.64.919.91.81.22.42.31.62.11.1-1.81.22.0-4.52.12.5
Progressive ratio test 2 active lever presses0.20.22.30.1-0.10.40.50.00.3-0.2-0.1-0.10.2-1.50.20.4
Progressive ratio test 2 breakpoint0.30.32.60.2-0.00.40.60.10.3-0.1-0.2-0.00.2-1.60.30.5
Progressive ratio test 2 inactive lever presses2.73.113.71.40.91.91.71.31.70.8-1.40.91.5-3.71.71.7
Total sessions with >9 infusions2.42.68.21.41.01.62.01.31.30.9-1.41.11.4-2.91.32.3
Short access day 1 total inactive lever presses5.05.69.72.22.12.62.32.22.41.9-2.32.12.4-3.12.42.3
Short access day 10 total inactive lever presses1.01.12.01.00.81.20.91.01.10.9-1.10.81.1-1.41.11.0
Short access day 1 total infusions5.25.515.42.11.72.52.72.02.21.5-2.11.72.2-3.92.22.8
Short access day 10 total infusions3.84.26.12.01.92.22.12.02.01.7-2.01.92.1-2.52.02.3
Short access total infusions3.03.49.11.71.31.92.11.51.71.2-1.61.41.7-3.01.72.2
Short access day 1 locomotion6.87.214.12.62.12.83.12.42.62.1-2.52.12.6-3.82.63.2
Short access day 10 total locomotion0.80.92.00.90.91.10.80.90.90.6-0.90.91.0-1.40.90.9
Short access total locomotion0.70.73.00.70.50.90.90.60.70.3-0.70.50.7-1.70.71.0
Compulsive drug intake0.70.75.0-0.5-0.1-0.8-0.9-0.4-0.70.00.5-0.2-0.62.2-0.6-0.9
One hour access (0.3 mA shock)1.82.13.51.41.21.61.51.41.61.3-1.41.21.5-1.91.51.4
One hour access (shock baseline)1.92.26.01.41.11.51.71.21.41.0-1.31.11.4-2.41.31.7
Number of responses in last shaping day0.70.74.30.60.10.81.00.40.70.2-0.50.10.6-2.10.71.1
Context. condit. distance diff. score0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.10.0-0.0-0.2
Locomotion velocity, session 10.10.10.5-0.1-0.30.0-0.2-0.20.0-0.30.1-0.4-0.1-0.70.0-0.3
Locomotion distance, session 11.82.42.91.61.61.61.41.61.71.7-1.61.61.6-1.11.61.0
Locomotion velocity, session 20.20.30.6-0.4-0.3-0.5-0.5-0.4-0.5-0.40.4-0.3-0.50.7-0.5-0.8
Locomotion distance, session 20.00.00.20.0-0.10.1-0.0-0.00.1-0.1-0.0-0.10.1-0.50.1-0.2
Locomotion velocity, session 30.60.71.00.80.70.90.90.80.90.7-0.80.60.8-1.00.91.0
Locomotion distance, session 30.91.01.21.00.91.10.91.01.10.9-1.00.91.0-0.91.10.8
Stereotopy head waving bouts, day 31.82.13.01.41.31.51.51.41.51.4-1.41.31.5-1.51.51.7
Stereotopy head waving duration, day 30.10.10.50.30.20.40.50.30.30.3-0.30.20.3-0.50.30.7
Locomotion velocity, session 71.11.23.01.00.81.21.21.01.20.8-1.00.81.1-1.71.21.0
Locomotion distance, session 70.10.21.40.2-0.00.40.30.10.4-0.2-0.2-0.00.2-1.20.30.0
Stereotopy head waving bouts, day 70.00.00.1-0.1-0.1-0.2-0.2-0.1-0.10.00.1-0.1-0.10.4-0.1-0.1
Stereotopy head waving duration, day 70.30.40.60.60.60.60.60.60.60.7-0.60.60.6-0.40.60.8
Locomotion velocity, session 80.30.43.20.40.00.60.80.30.50.1-0.40.10.4-1.80.60.3
Locomotion distance, session 80.30.50.80.70.60.80.70.60.80.5-0.70.60.7-0.90.80.2
Degree of sensitization distance0.80.81.1-0.9-1.0-0.9-0.8-1.0-0.9-1.10.9-1.0-0.90.3-0.9-0.9
Degree of sensitization stereotypy0.20.20.9-0.4-0.3-0.5-0.6-0.3-0.5-0.20.4-0.3-0.40.9-0.5-0.5
Condit. Reinf. active minus inactive responses0.60.71.7-0.8-0.7-0.9-0.8-0.7-0.9-0.60.8-0.7-0.81.3-0.9-0.9
Condit. Reinf. active-inactive response ratio0.80.82.2-0.9-0.7-1.0-0.9-0.8-1.0-0.70.8-0.7-0.91.5-1.0-0.7
Condit. Reinf. active responses0.20.20.50.50.60.40.30.60.40.7-0.50.60.50.60.40.1
Condit. Reinf. inactive responses1.72.02.41.51.51.51.31.51.51.5-1.51.51.5-0.81.51.0
Incentive salience index mean0.00.10.30.10.30.10.20.20.10.3-0.20.30.20.60.10.0
Condit. Reinf. lever presses0.60.81.20.91.10.80.81.00.81.1-0.91.10.90.20.80.6
Time in familiar zone, hab. session 10.70.71.2-0.8-0.9-0.7-0.7-0.9-0.8-1.10.9-0.9-0.8-0.1-0.8-0.8
Time in novel zone, hab. session 10.70.70.8-0.9-0.8-0.9-0.8-0.8-0.9-0.70.8-0.8-0.90.9-0.9-0.3
Total zone transitions, hab. session 10.10.10.20.40.40.40.40.40.40.4-0.40.40.4-0.10.30.1
Total locomotion distance, hab. session 10.20.20.60.50.30.50.60.40.50.3-0.40.30.5-0.80.50.3
Locomotion velocity, hab. session 11.01.41.61.31.11.31.21.21.31.2-1.21.21.3-0.91.20.9
Time in familiar zone, hab. session 20.00.00.40.1-0.10.20.20.00.2-0.2-0.1-0.10.1-0.60.2-0.1
Time in novel zone, hab. session 20.60.61.6-0.7-0.5-0.9-0.8-0.7-0.9-0.50.7-0.5-0.81.3-0.9-0.5
Total zone transitions, hab. session 20.10.10.30.40.50.30.30.40.30.5-0.40.50.40.20.3-0.0
Total locomotion distance, hab. session 20.20.30.40.60.50.60.60.60.50.6-0.60.50.6-0.30.50.2
Locomotion velocity, hab. session 20.40.60.80.80.80.80.80.80.80.9-0.80.80.8-0.30.70.4
Novel to familiar place preference ratio1.01.12.4-1.0-0.8-1.1-1.1-1.0-1.1-0.71.0-0.8-1.01.5-1.1-1.0
Novelty place preference1.71.73.1-1.3-1.1-1.4-1.4-1.2-1.4-1.01.3-1.1-1.31.8-1.4-1.2
Time in novel zone, NPP test1.92.03.1-1.4-1.2-1.5-1.5-1.4-1.5-1.21.4-1.2-1.41.7-1.5-1.2
Total zone transitions, NPP test1.42.02.21.51.51.51.31.51.51.4-1.51.51.5-1.01.51.2
Total locomotion distance, NPP test1.92.62.91.71.61.71.61.71.71.6-1.71.61.7-1.41.71.6
Locomotion velocity, NPP test3.24.65.02.22.22.22.12.22.22.2-2.22.22.2-1.52.21.9
Pavlov. Cond. lever latency1.72.22.6-1.5-1.5-1.6-1.4-1.5-1.6-1.41.5-1.5-1.51.4-1.5-1.2
Pavlov. Cond. magazine entry latency0.00.00.10.20.10.20.20.10.20.0-0.20.10.2-0.30.20.1
Pavlov. Cond. change in total contacts0.00.00.10.20.30.20.20.20.20.2-0.20.30.2-0.10.2-0.0
Pavlov. Cond. index score0.70.91.11.01.01.00.91.01.10.9-1.01.01.0-0.91.00.7
Pavlov. Cond. latency score0.70.91.10.90.91.00.91.01.10.8-1.00.91.0-0.91.00.7
Pavlov. Cond. lever contacts1.01.21.51.11.21.21.11.21.21.2-1.21.21.2-0.71.10.8
Pavlov. Cond. magazine entry number0.40.60.8-0.7-0.6-0.8-0.7-0.7-0.8-0.60.8-0.6-0.80.9-0.8-0.6
Pavlov. Cond. intertrial magazine entries1.21.42.01.21.41.11.11.31.11.4-1.21.41.2-0.31.11.2
Pavlov. Cond. lever-magazine prob. diff.1.51.92.21.41.51.41.41.41.51.4-1.41.51.4-1.01.41.1
Pavlov. Cond. response bias1.41.72.01.31.31.41.31.41.41.3-1.41.31.4-1.11.41.2
Bone: apparent density5.28.69.33.03.03.12.93.03.03.0-3.03.03.1-2.33.02.5
Bone surface2.74.75.52.22.12.32.22.22.32.0-2.22.12.3-2.12.31.6
Bone volume2.84.85.52.32.12.42.22.22.32.1-2.32.12.3-2.12.31.6
Bone: connectivity density4.97.78.52.92.92.92.82.92.92.9-2.92.92.9-1.92.92.5
Bone: cortical apparent density0.30.40.70.70.80.60.70.70.60.8-0.70.80.7-0.10.70.3
Bone: cortical area0.30.50.60.70.70.70.70.70.70.6-0.70.70.7-0.60.70.1
Bone: cortical porosity1.51.62.51.21.21.31.31.21.21.1-1.21.21.2-1.61.31.5
Bone: cortical porosity1.31.42.21.11.11.21.21.11.21.0-1.11.11.1-1.51.21.3
Bone: cortical thickness0.00.10.6-0.2-0.1-0.1-0.3-0.1-0.1-0.20.1-0.1-0.10.2-0.1-0.8
Bone: cortical thickness1.51.82.01.41.31.41.31.41.41.4-1.41.31.4-1.11.41.1
Bone: cortical tissue density0.20.30.50.60.70.50.60.60.50.6-0.60.70.6-0.10.50.2
Bone: elastic displacement0.80.91.40.91.10.80.91.00.81.1-0.91.10.9-0.20.81.2
Bone: elastic work1.01.32.01.21.31.11.11.21.11.4-1.21.31.2-0.31.01.1
Bone: endosteal estimation0.40.91.21.00.81.01.10.91.00.8-0.90.81.0-1.11.00.8
Bone: endosteal perimeter0.10.30.40.60.60.60.60.60.60.5-0.60.60.6-0.40.60.3
Bone: final force0.10.20.60.50.40.50.60.40.50.3-0.40.40.5-0.80.5-0.0
Bone: final moment0.20.30.60.50.40.60.70.50.50.4-0.50.50.5-0.80.50.1
Bone: marrow area0.40.91.31.00.91.01.10.91.00.9-1.00.91.0-1.11.00.8
Bone: maximum diameter0.81.51.81.31.31.31.31.31.31.2-1.31.31.3-1.01.30.8
Bone: maximum force0.00.10.40.20.10.20.30.10.2-0.0-0.10.10.2-0.60.2-0.1
Bone: maximum moment0.10.10.40.30.20.30.40.20.30.1-0.30.20.3-0.60.3-0.0
Bone: minimum diameter0.10.20.4-0.3-0.4-0.3-0.2-0.4-0.3-0.50.4-0.4-0.4-0.2-0.3-0.7
Bone: periosteal estimation0.61.21.41.11.11.21.21.11.21.0-1.11.11.2-1.11.20.7
Bone: periosteal perimeter0.20.30.40.60.60.60.60.60.60.6-0.60.60.6-0.30.60.1
Bone: post-yield work0.50.61.00.80.80.80.90.70.80.6-0.80.80.8-1.00.80.9
Bone: stiffness0.00.00.2-0.1-0.2-0.1-0.0-0.2-0.0-0.30.1-0.2-0.1-0.3-0.0-0.4
Bone: tissue strength1.00.92.5-0.9-0.7-1.0-1.0-0.8-1.0-0.70.9-0.7-0.91.6-1.0-1.1
Bone: trabecular number4.16.36.92.62.62.62.42.62.62.5-2.62.62.6-1.92.62.3
Bone: trabecular spacing3.54.56.4-2.1-1.9-2.3-2.3-2.0-2.2-1.82.1-1.9-2.12.5-2.2-2.0
Bone: trabecular thickness0.81.02.11.00.81.11.20.91.00.8-1.00.81.0-1.41.00.8
Bone: trabecular tissue density0.20.31.00.50.40.60.60.40.50.4-0.50.40.5-1.00.60.4
Breakpoint value in progressive ratio session1.21.32.01.21.21.01.41.21.01.4-1.11.21.1-0.31.01.4
Distance traveled before self-admin0.00.00.20.20.30.10.10.20.20.1-0.20.30.10.40.1-0.2
Distance traveled after self-admin0.70.81.8-0.8-0.6-0.9-1.1-0.8-0.7-0.80.8-0.7-0.91.3-0.9-1.2
Delta time in closed arm before/after self-admin0.00.00.1-0.1-0.2-0.1-0.1-0.1-0.1-0.00.1-0.2-0.10.2-0.3-0.2
Delta time in open arm before/after self-admin0.30.30.40.60.60.60.50.60.50.4-0.60.60.6-0.50.60.6
Diff in mean of infusions in LGA sessions0.30.30.40.60.60.50.70.50.50.5-0.50.60.5-0.60.50.5
Extinction: sum of active levers before priming0.50.51.00.70.80.50.60.80.61.0-0.70.80.70.50.50.5
Active lever presses in extinction session 60.60.62.60.60.30.61.00.40.60.2-0.50.30.5-1.60.51.3
Delta distance traveled before/after self-admin1.31.41.8-1.2-1.3-1.1-1.3-1.3-1.1-1.41.2-1.3-1.20.3-1.1-1.2
Delta ambulatory time before/after self-admin0.20.20.4-0.5-0.5-0.4-0.5-0.5-0.3-0.70.5-0.5-0.5-0.2-0.4-0.5
Time in closed arm before self-admin0.40.50.8-0.7-0.7-0.7-0.4-0.8-0.9-0.80.8-0.7-0.70.1-0.7-0.6
Time in closed arm after self-admin1.31.41.9-1.2-1.1-1.3-0.9-1.3-1.4-1.31.3-1.1-1.30.8-1.3-0.9
Time in open arm before self-admin0.20.22.10.10.4-0.0-0.40.30.20.5-0.20.40.11.5-0.0-0.2
Time in open arm after self-admin2.02.22.91.51.71.51.01.61.61.7-1.61.61.6-0.51.61.2
Sum of active levers in priming session hrs 5-60.90.91.40.91.10.90.61.00.91.2-1.01.11.00.00.90.7
Time to tail flick, vehicle, before self-admin2.52.52.9-1.6-1.7-1.7-1.5-1.7-1.7-1.71.7-1.7-1.71.2-1.7-1.3
Time to tail flick, vehicle, after self-admin4.24.56.0-2.1-2.2-2.2-1.7-2.2-2.3-2.32.2-2.1-2.21.4-2.5-1.9
Time to tail flick, test, before self-admin0.50.50.80.70.80.70.70.70.70.8-0.70.80.7-0.50.60.9
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.3-0.3-0.2-0.3-0.4-0.40.3-0.2-0.3-0.1-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.1-0.0-0.10.1-0.2-0.2-0.20.1-0.0-0.1-0.4-0.2-0.1
Delta time to tail flick, test, before/after SA0.30.30.50.50.50.60.50.60.60.5-0.60.50.6-0.70.60.3
Ambulatory time before self-admin0.10.10.30.40.50.30.20.40.40.4-0.40.50.40.50.30.1
Ambulatory time after self-admin0.50.50.9-0.7-0.6-0.7-0.9-0.7-0.5-0.70.7-0.6-0.70.9-0.7-1.0
Total heroin consumption2.73.34.31.92.01.81.81.91.92.1-1.92.01.9-0.81.71.7
Area under the delay curve0.50.54.00.30.7-0.10.20.4-0.10.9-0.30.70.22.0-0.1-0.3
Delay disc. indifference point, 0s delay3.23.59.3-1.7-1.3-2.0-1.9-1.6-1.9-1.31.7-1.3-1.83.0-1.9-2.2
Delay disc. indifference point, 16s delay0.70.73.50.61.10.20.30.80.31.2-0.61.10.51.90.30.1
Delay disc. indifference point, 2s delay0.30.30.7-0.5-0.5-0.5-0.5-0.5-0.5-0.30.5-0.5-0.50.7-0.5-0.8
Delay disc. indifference point, 24s delay2.72.67.81.42.10.61.11.60.82.3-1.42.21.22.80.80.7
Delay disc. indifference point, 4s delay0.00.00.10.0-0.00.10.10.10.10.3-0.1-0.00.10.10.1-0.3
Delay disc. indifference point, 8s delay0.50.53.50.40.8-0.00.30.50.00.9-0.40.80.31.90.0-0.1
Delay discount exponential model param0.60.73.4-0.6-1.0-0.2-0.4-0.7-0.2-1.20.6-1.0-0.5-1.8-0.2-0.1
Delay discount hyperbolic model param0.50.52.0-0.6-0.9-0.2-0.5-0.7-0.3-1.10.6-0.9-0.5-1.4-0.3-0.1
Fecal boli incidents, locomotor time 10.30.30.50.60.70.50.40.60.60.4-0.50.70.5-0.20.60.5
Change in fecal boli incidents, locomotor task4.64.34.9-2.1-2.1-2.2-2.0-2.0-2.2-2.02.1-2.1-2.12.1-2.2-2.0
Time >=10cm from walls, locomotor time 10.30.32.7-0.20.0-0.4-0.2-0.1-0.40.30.20.0-0.21.6-0.5-0.4
Bouts of movement, locomotor time 12.42.63.21.81.81.61.81.71.61.6-1.71.81.7-0.91.71.3
Total resting periods, locomotor time 12.73.03.41.81.81.81.81.81.81.7-1.81.81.8-1.41.81.5
Rest time, locomotor task time 10.10.10.50.20.20.30.30.20.20.1-0.20.20.2-0.70.20.4
Distance moved, locomotor task time 11.31.43.1-1.2-1.0-1.2-1.2-1.1-1.1-0.81.1-1.0-1.21.8-1.3-1.2
Vertical activity count, locomotor time 10.60.72.5-0.7-0.5-0.8-0.8-0.6-0.7-0.30.7-0.5-0.71.6-0.9-1.0
Time >=10cm from walls, locomotor time 20.20.31.80.3-0.10.40.80.20.30.1-0.3-0.10.3-1.30.40.3
Bouts of movement, locomotor time 20.10.10.5-0.2-0.2-0.3-0.3-0.3-0.3-0.10.3-0.2-0.30.3-0.2-0.7
Total resting periods, locomotor time 20.00.00.10.00.00.10.0-0.00.10.0-0.00.00.0-0.30.2-0.3
Rest time, locomotor task time 21.41.61.91.31.41.31.11.31.31.4-1.31.41.3-0.81.31.1
Distance moved, locomotor task time 20.91.11.4-1.1-1.2-1.0-0.8-1.1-1.1-1.01.1-1.2-1.10.5-1.1-0.9
Vertical activity count, locomotor time 20.50.60.9-0.8-0.9-0.7-0.3-0.9-0.7-1.00.8-0.9-0.8-0.3-0.7-0.5
Weight adjusted by age0.10.10.8-0.1-0.40.10.3-0.1-0.1-0.30.0-0.40.0-0.9-0.10.4
Seeking ratio, delayed vs. immediate footshock0.40.44.0-0.2-0.50.10.0-0.40.0-0.80.2-0.5-0.1-2.00.10.2
Locomotion in novel chamber0.91.11.5-1.0-1.1-1.2-1.0-1.1-1.1-1.21.1-1.1-1.10.7-1.0-0.8
Locomotion in novel chamber post-restriction2.32.84.3-1.6-1.4-1.8-1.6-1.6-2.0-1.51.6-1.4-1.72.1-1.9-1.4
Progressive ratio0.20.32.7-0.0-0.50.30.5-0.1-0.0-0.20.0-0.40.0-1.60.10.6
Food seeking constrained by brief footshock4.04.910.62.01.72.32.51.92.21.9-2.01.72.1-3.32.22.7
Seeking ratio, punishment vs. effort0.60.71.30.91.20.70.50.90.91.0-0.91.10.80.40.80.5
Run reversals in cocaine runway, females0.30.32.3-0.30.1-0.5-0.5-0.1-0.40.10.20.1-0.31.5-0.4-0.4
Run reversals in cocaine runway, males0.30.31.00.40.70.20.30.50.20.7-0.40.70.41.00.20.2
Latency to leave start box in cocaine runway0.60.61.00.80.70.80.70.71.00.5-0.80.70.8-1.00.90.7
Latency to leave start box in cocaine runway, F0.60.70.90.80.90.80.70.81.00.7-0.80.90.8-0.60.90.8
Latency to leave start box in cocaine runway, M0.70.73.40.80.40.80.90.60.80.3-0.70.40.7-1.80.80.9
Cd content in liver0.00.00.10.10.10.10.10.10.10.0-0.10.20.1-0.10.1-0.3
Co content in liver5.36.27.42.62.72.52.52.62.62.6-2.62.72.6-1.72.42.2
Cu content in liver0.00.00.10.20.20.20.40.20.20.2-0.20.20.2-0.20.10.2
Fe content in liver0.10.10.4-0.2-0.3-0.1-0.0-0.2-0.1-0.30.2-0.3-0.1-0.6-0.10.4
K content in liver0.10.10.3-0.2-0.3-0.1-0.1-0.2-0.1-0.20.2-0.3-0.2-0.1-0.1-0.5
Mg content in liver0.20.20.5-0.4-0.5-0.3-0.3-0.4-0.3-0.40.4-0.5-0.30.1-0.4-0.7
Mn content in liver0.60.71.00.80.70.90.80.80.80.7-0.80.70.8-1.00.91.0
Na content in liver0.60.61.80.70.60.90.70.60.80.5-0.70.50.7-1.40.80.8
Rb content in liver0.00.00.0-0.1-0.1-0.10.0-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1
Se content in liver0.30.40.7-0.6-0.9-0.5-0.3-0.7-0.6-0.90.7-0.8-0.6-0.4-0.5-0.4
Sr content in liver0.20.20.8-0.2-0.1-0.3-0.4-0.2-0.3-0.10.2-0.1-0.30.9-0.3-0.7
Zn content in liver1.31.42.1-1.2-1.2-1.2-0.9-1.2-1.2-1.21.2-1.2-1.20.8-1.2-1.4