Fam81a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000057501 0.16 0.12 6.9e-14 0.15 0.15 0.15 0.15 1.1e-13 5.7e-14 5.2e-14 8.8e-14
2 Brain mRNA stability ENSRNOG00000057501 0.04 0.04 7.7e-04 0.03 0.03 0.03 0.03 4.9e-04 2.0e-03 8.7e-04 9.1e-04
3 IL gene expression ENSRNOG00000057501 0.29 0.2 1.2e-05 0.19 0.2 0.26 0.21 3.1e-05 2.0e-05 5.5e-07 9.9e-06
4 NAcc mRNA stability ENSRNOG00000057501 0.04 0.03 1.9e-03 0.03 0.03 0.03 0.03 1.4e-03 1.4e-03 3.0e-03 1.8e-03
5 OFC mRNA stability ENSRNOG00000057501 0.22 0.18 4.8e-04 0.11 0.12 0.09 0.09 1.5e-03 8.9e-04 3.9e-03 3.4e-03
6 PL gene expression ENSRNOG00000057501 0.1 0.07 1.3e-09 0.12 0.12 0.11 0.12 4.7e-09 1.9e-09 5.5e-09 3.5e-09
7 PL intron excision ratio chr8:70803970:70820689 0.03 0.03 2.3e-03 0.02 0.02 0.02 0.01 1.2e-02 9.3e-03 1.8e-02 2.7e-02
8 PL intron excision ratio chr8:70803970:70821437 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.01 1.4e-02 8.4e-03 1.8e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail6.420.826.8-4.6-3.9-5.2-4.5-4.5-4.54.5-4.5
BMI without tail3.06.28.5-2.3-2.2-2.9-2.5-2.5-2.52.5-2.5
Body weight4.820.220.7-4.5-4.3-4.4-4.5-4.5-4.54.5-4.5
Epididymis fat weight0.00.10.1-0.2-0.2-0.4-0.2-0.2-0.20.2-0.2
Glucose0.30.41.1-0.6-1.00.1-0.7-0.6-0.60.6-0.6
Heart weight0.40.50.7-0.8-0.5-0.7-0.7-0.7-0.70.7-0.7
Left kidney weight2.67.58.3-2.9-2.4-2.6-2.8-2.8-2.82.8-2.8
Right kidney weight2.77.88.2-2.9-2.8-2.3-2.9-2.9-2.92.9-2.9
Tail length0.10.20.4-0.3-0.6-0.2-0.5-0.5-0.50.5-0.5
Length with tail0.82.94.3-1.7-2.1-0.7-1.8-1.8-1.81.8-1.8
Length without tail2.35.16.2-2.5-2.1-1.8-2.3-2.3-2.32.3-2.3
Liver weight, left0.50.81.7-0.9-1.3-0.1-0.9-0.9-0.90.9-0.9
Liver weight, right1.32.14.4-1.5-2.1-0.1-1.5-1.5-1.41.4-1.4
Parametrial fat weight0.00.10.60.2-0.20.80.10.10.1-0.10.1
Retroperitoneal fat weight0.00.10.3-0.2-0.60.4-0.2-0.2-0.20.2-0.2
Intraocular pressure0.00.00.0-0.10.00.1-0.1-0.1-0.10.1-0.1
Extensor digitorum longus weight7.730.832.6-5.7-5.6-4.7-5.7-5.7-5.75.7-5.7
Soleus weight16.247.350.1-6.9-7.1-5.9-7.0-7.0-7.07.0-7.0
Tibialis anterior weight12.242.244.2-6.6-6.6-5.5-6.6-6.6-6.66.6-6.6
Tibia length0.00.10.30.30.6-0.10.30.30.3-0.30.3
Number of licking bursts2.63.14.11.71.52.01.71.81.8-1.81.8
Food consumed during 24 hour testing period1.11.31.8-1.2-0.8-1.4-1.1-1.1-1.21.2-1.2
Times rat made contact with spout0.20.20.60.30.8-0.10.40.40.4-0.40.4
Mean time between licks in bursts0.30.40.40.60.60.50.60.60.6-0.60.6
Mean num. licks in bursts1.51.93.3-1.3-0.9-1.8-1.3-1.3-1.41.4-1.3
Std. dev. time between licks in bursts0.20.30.6-0.4-0.8-0.2-0.5-0.5-0.50.5-0.5
Water consumed over 24 hours0.30.40.60.50.80.40.60.60.6-0.60.6
Indifference point 0 sec0.10.20.5-0.4-0.70.2-0.4-0.4-0.40.4-0.4
Indifference point AUC0.10.10.50.2-0.50.70.10.10.1-0.10.1
Indifference point function ln k0.40.61.0-0.8-0.3-1.0-0.7-0.7-0.80.7-0.7
Indifference point function log k0.40.61.0-0.8-0.3-1.0-0.7-0.7-0.80.7-0.7
Delay discounting total patch changes 0 sec0.20.30.6-0.5-0.80.0-0.5-0.5-0.50.5-0.5
Delay discounting total patch changes 12 sec0.10.10.20.3-0.30.50.10.20.2-0.20.2
Delay discounting total patch changes 18 sec0.10.10.3-0.3-0.6-0.2-0.4-0.4-0.40.4-0.4
Delay discounting total patch changes 24 sec0.10.10.70.2-0.60.8-0.00.00.0-0.00.0
Delay discounting total patch changes 6 sec0.30.41.1-0.5-1.10.0-0.6-0.6-0.60.6-0.6
Delay discounting time to switch 0 sec0.91.42.31.21.50.51.21.21.2-1.21.2
Delay discounting water rate 0 sec2.03.23.9-1.8-2.0-1.4-1.9-1.8-1.81.8-1.8
Delay discounting water rate 12 sec3.14.66.6-2.2-2.6-1.0-2.2-2.2-2.22.2-2.2
Delay discounting water rate 18 sec0.30.40.7-0.6-0.8-0.2-0.7-0.6-0.70.7-0.7
Delay discounting water rate 24 sec0.20.30.6-0.4-0.8-0.1-0.5-0.5-0.50.5-0.5
Delay discounting water rate 6 sec1.11.71.9-1.4-1.3-1.0-1.3-1.3-1.31.3-1.3
Locomotor activity6.410.210.9-3.3-2.9-3.0-3.2-3.3-3.33.3-3.3
Locomotor testing distance3.55.76.2-2.5-2.0-2.4-2.4-2.4-2.52.5-2.4
Locomotor testing rearing2.23.44.3-1.8-1.4-2.1-1.8-1.8-1.91.9-1.9
Light reinforcement 12.13.95.7-2.0-2.4-1.2-2.1-2.0-2.02.0-2.0
Light reinforcement 20.40.61.50.70.31.20.70.70.7-0.70.7
Reaction time number correct1.92.73.5-1.7-1.3-1.9-1.6-1.6-1.61.6-1.6
Reaction time mean minus median0.20.31.00.5-0.01.00.40.40.4-0.40.4
Reaction time mean minus median AUC1.01.23.01.10.51.71.01.01.0-1.01.0
Reaction time num false alarms0.91.22.11.10.71.41.11.11.1-1.11.1
Reaction time num false alarms AUC0.30.51.30.60.21.10.60.60.7-0.70.7
Reaction time trials correct on left1.92.73.5-1.7-1.3-1.9-1.6-1.6-1.61.6-1.6
Reaction time trials on left2.02.83.4-1.7-1.4-1.9-1.7-1.7-1.71.7-1.7
Reaction time mean3.14.36.02.11.62.52.02.12.1-2.12.1
Reaction time mean AUC2.33.14.61.81.32.11.71.71.8-1.81.8
Median of all reaction times4.56.17.22.52.12.72.42.52.5-2.52.5
Reaction time omissions0.20.30.4-0.6-0.60.1-0.6-0.6-0.60.6-0.6
Reaction time false alarm rate1.92.64.51.61.02.11.61.61.6-1.61.6
Reaction time premature initiation rate1.52.02.4-1.5-1.5-0.8-1.5-1.5-1.41.4-1.4
Reaction time premature initiations2.73.94.3-2.1-2.0-1.5-2.0-2.0-2.02.0-2.0
Std. dev. reaction times1.11.63.01.30.71.71.21.21.2-1.21.2
Reaction time trials completed2.02.83.4-1.7-1.4-1.9-1.7-1.7-1.71.7-1.7
Reaction time trials AUC1.62.43.2-1.6-1.2-1.8-1.5-1.5-1.51.5-1.5
Social response proportion0.00.00.20.00.4-0.40.10.10.1-0.10.1
Social responses0.10.10.2-0.2-0.5-0.0-0.3-0.3-0.30.3-0.3
Social time0.20.31.5-0.5-0.1-1.2-0.4-0.4-0.40.4-0.4
Conditioned locomotion0.10.10.20.30.30.40.30.30.3-0.30.3
Cocaine response after cond. corrected3.03.43.6-1.9-1.8-1.6-1.9-1.9-1.91.9-1.9
Cocaine response after cond. not corrected1.51.71.8-1.3-1.3-1.1-1.3-1.4-1.31.3-1.3
Cocaine response before conditioning1.11.31.41.21.10.91.21.21.2-1.21.2
Saline control response0.10.10.40.10.5-0.60.10.10.1-0.10.1
Condit. Reinf. active minus inactive responses2.53.03.7-1.7-1.9-1.4-1.8-1.8-1.81.8-1.8
Condit. Reinf. active-inactive response ratio1.11.11.3-1.0-0.9-1.1-1.1-1.1-1.11.1-1.1
Condit. Reinf. active responses1.01.52.2-1.1-1.5-0.8-1.3-1.2-1.21.2-1.2
Condit. Reinf. inactive responses0.10.20.70.4-0.10.80.30.30.3-0.30.3
Condit. Reinf. lever presses0.71.01.21.10.81.11.01.01.0-1.01.0
Condit. Reinf. lever reinforcers received0.50.81.2-0.8-1.1-0.6-0.9-0.9-0.90.9-0.9
Pavlov. Cond. lever latency0.91.22.0-1.2-0.8-1.4-1.1-1.1-1.11.1-1.1
Pavlov. Cond. magazine entry latency3.54.04.22.01.82.02.02.02.0-2.02.0
Pavlov. Cond. change in total contacts0.40.60.70.80.70.80.70.80.8-0.80.7
Pavlov. Cond. index score1.21.62.11.30.91.51.21.21.3-1.31.2
Pavlov. Cond. latency score0.81.01.41.10.71.20.91.01.0-1.01.0
Pavlov. Cond. lever contacts0.30.40.80.70.40.90.60.60.6-0.60.6
Pavlov. Cond. magazine entry number3.44.24.7-2.1-1.7-2.2-2.0-2.1-2.12.1-2.1
Pavlov. Cond. intertrial magazine entries0.50.70.9-0.8-1.0-0.5-0.9-0.9-0.90.9-0.9
Pavlov. Cond. lever-magazine prob. diff.1.41.82.41.41.01.61.31.31.3-1.31.3
Pavlov. Cond. response bias1.21.72.11.41.11.41.31.31.3-1.31.3
Conditioned reinforcement - actives0.50.52.2-0.70.4-1.5-0.5-0.5-0.60.6-0.5
Conditioned reinforcement - inactives0.00.00.1-0.10.2-0.0-0.0-0.0-0.00.0-0.0
Conditioned locomotion0.30.30.70.50.80.30.60.60.6-0.60.6
Intermittent access intake day 1-15 change1.00.91.80.91.30.61.01.01.0-1.01.0
Intermittent access intake escalation1.21.22.41.01.50.51.11.11.1-1.11.1
Intermittent access intake escalation 20.10.10.3-0.10.5-0.6-0.0-0.0-0.10.1-0.0
Intermitt. access day 1 inactive lever presses1.81.92.01.41.41.31.41.41.4-1.41.4
Intermitt. access day 15 inactive lever presses0.10.10.50.10.7-0.50.20.20.1-0.20.2
Intermitt. access escalation Index1.41.21.4-1.1-1.0-1.2-1.1-1.1-1.11.1-1.1
Intermittent access day 1 total infusions0.30.30.60.50.70.30.60.50.5-0.50.6
Intermittent access day 15 total infusions1.11.23.01.01.70.31.11.11.0-1.01.1
Intermittent access terminal intake (last 3 days)0.30.41.50.41.2-0.20.60.50.5-0.50.5
Intermittent access total infusions0.20.20.80.40.90.10.50.40.4-0.40.4
Intermittent access day 1 locomotion1.71.82.31.31.51.01.41.41.3-1.31.4
Intermittent access day 15 total locomotion1.71.92.91.31.71.01.41.41.3-1.31.3
Intermittent access total locomotion0.10.10.3-0.00.6-0.40.10.10.0-0.00.0
Intermittent access standard deviation1.01.02.30.91.50.21.11.01.0-1.01.0
Cocaine induced anxiety0.00.00.00.20.2-0.10.20.20.2-0.20.2
Post-drug Anxiety1.92.12.21.51.31.41.51.51.5-1.51.5
Baseline Anxiety0.50.50.70.70.70.90.70.70.7-0.70.7
Lifetime Intake0.40.40.80.60.90.50.70.60.6-0.60.6
Incentive Sensitization - Responses0.50.51.0-0.7-0.4-1.0-0.6-0.7-0.70.7-0.7
Incentive Sensitization - Breakpoint0.30.30.7-0.5-0.2-0.8-0.5-0.5-0.50.5-0.5
Progressive ratio test 1 active lever presses0.10.10.2-0.4-0.1-0.3-0.4-0.4-0.40.4-0.4
Progressive ratio test 1 breakpoint0.00.00.1-0.00.30.00.00.0-0.0-0.00.0
Progressive ratio test 1 inactive lever presses1.41.52.11.21.01.41.21.21.2-1.21.2
Progressive ratio test 2 active lever presses0.30.30.7-0.5-0.0-0.8-0.5-0.5-0.50.5-0.5
Progressive ratio test 2 breakpoint0.40.40.6-0.7-0.3-0.8-0.7-0.7-0.70.7-0.7
Progressive ratio test 2 inactive lever presses0.50.51.30.61.10.30.70.70.7-0.70.7
Total sessions with >9 infusions0.10.10.40.20.10.60.20.20.3-0.30.3
Short access day 1 total inactive lever presses0.20.30.70.50.30.80.50.50.5-0.50.5
Short access day 10 total inactive lever presses0.70.81.60.81.30.40.90.90.9-0.90.9
Short access day 1 total infusions0.30.30.50.50.70.40.60.60.6-0.60.6
Short access day 10 total infusions0.30.40.50.60.60.70.60.60.6-0.60.6
Short access total infusions0.91.01.21.01.01.11.01.01.0-1.01.0
Short access day 1 locomotion0.10.10.20.20.40.40.30.30.3-0.30.3
Short access day 10 total locomotion0.00.00.0-0.0-0.20.1-0.1-0.1-0.00.0-0.0
Short access total locomotion0.91.01.10.91.01.01.01.01.0-1.01.0
Compulsive drug intake0.20.20.7-0.4-0.80.3-0.4-0.4-0.40.4-0.4
One hour access (0.3 mA shock)0.10.10.2-0.4-0.0-0.4-0.3-0.3-0.30.3-0.3
One hour access (shock baseline)0.30.31.00.41.00.00.50.50.5-0.50.5
Number of responses in last shaping day0.00.00.10.00.4-0.30.10.10.1-0.10.1
Context. condit. distance diff. score1.01.21.31.11.10.91.11.11.1-1.11.1
Locomotion velocity, session 10.70.72.2-0.7-1.50.6-0.8-0.8-0.70.7-0.7
Locomotion distance, session 10.50.71.40.80.41.20.80.80.8-0.80.8
Locomotion velocity, session 20.10.10.3-0.2-0.50.4-0.2-0.2-0.20.2-0.2
Locomotion distance, session 20.00.00.2-0.0-0.40.3-0.1-0.1-0.10.1-0.1
Locomotion velocity, session 30.20.20.70.5-0.10.80.30.30.4-0.40.4
Locomotion distance, session 32.72.94.41.81.22.11.71.71.7-1.71.7
Stereotopy head waving bouts, day 31.01.22.5-1.1-0.7-1.6-1.0-1.1-1.11.1-1.1
Stereotopy head waving duration, day 31.11.42.7-1.2-0.7-1.6-1.1-1.1-1.11.1-1.1
Locomotion velocity, session 72.42.63.71.71.21.91.61.61.6-1.61.6
Locomotion distance, session 72.02.63.11.61.41.81.61.61.6-1.61.6
Stereotopy head waving bouts, day 72.22.55.0-1.5-1.0-2.2-1.5-1.5-1.61.6-1.6
Stereotopy head waving duration, day 72.02.55.0-1.5-0.9-2.2-1.5-1.5-1.61.6-1.6
Locomotion velocity, session 80.20.31.5-0.1-0.81.2-0.1-0.1-0.00.0-0.0
Locomotion distance, session 81.01.52.01.20.91.41.21.21.2-1.21.2
Degree of sensitization distance0.10.10.30.10.5-0.30.30.20.2-0.20.2
Degree of sensitization stereotypy1.21.42.3-1.1-0.8-1.5-1.1-1.1-1.21.2-1.2
Condit. Reinf. active minus inactive responses0.00.00.00.1-0.10.10.10.10.1-0.10.1
Condit. Reinf. active-inactive response ratio0.50.60.60.80.70.60.80.80.8-0.80.8
Condit. Reinf. active responses0.40.50.9-0.6-0.9-0.6-0.7-0.7-0.70.7-0.7
Condit. Reinf. inactive responses1.21.42.0-1.1-1.4-0.8-1.2-1.2-1.21.2-1.2
Incentive salience index mean0.00.00.10.2-0.20.30.10.10.1-0.10.1
Condit. Reinf. lever presses0.10.20.70.4-0.10.80.30.40.4-0.40.4
Time in familiar zone, hab. session 10.10.10.20.40.10.50.30.30.3-0.30.3
Time in novel zone, hab. session 10.00.00.0-0.10.1-0.00.10.10.1-0.10.1
Total zone transitions, hab. session 11.01.42.51.10.71.61.11.11.2-1.21.2
Total locomotion distance, hab. session 10.10.20.60.40.20.80.40.40.4-0.40.4
Locomotion velocity, hab. session 10.00.00.10.0-0.00.30.10.10.1-0.10.1
Time in familiar zone, hab. session 20.10.10.30.40.00.50.30.30.3-0.30.3
Time in novel zone, hab. session 20.00.00.1-0.00.3-0.30.10.10.0-0.00.0
Total zone transitions, hab. session 20.10.20.6-0.2-0.70.8-0.2-0.2-0.10.1-0.2
Total locomotion distance, hab. session 20.50.61.0-0.9-1.0-0.2-0.8-0.8-0.80.8-0.8
Locomotion velocity, hab. session 20.20.30.5-0.6-0.70.1-0.5-0.5-0.50.5-0.5
Novel to familiar place preference ratio1.51.62.6-1.2-0.9-1.6-1.2-1.2-1.31.3-1.3
Novelty place preference1.51.62.3-1.2-1.0-1.5-1.2-1.2-1.31.3-1.3
Time in novel zone, NPP test1.81.92.8-1.3-1.1-1.7-1.4-1.4-1.41.4-1.4
Total zone transitions, NPP test0.10.10.4-0.4-0.60.2-0.3-0.3-0.30.3-0.3
Total locomotion distance, NPP test0.50.70.9-0.9-1.0-0.6-0.8-0.8-0.80.8-0.8
Locomotion velocity, NPP test0.20.20.3-0.6-0.6-0.3-0.5-0.5-0.50.5-0.5
Pavlov. Cond. lever latency0.10.10.20.30.50.20.30.30.3-0.30.3
Pavlov. Cond. magazine entry latency0.91.21.91.10.71.41.11.11.1-1.11.1
Pavlov. Cond. change in total contacts0.00.00.1-0.1-0.1-0.3-0.1-0.1-0.10.1-0.1
Pavlov. Cond. index score0.60.71.10.90.51.00.90.90.9-0.90.9
Pavlov. Cond. latency score0.30.30.60.60.20.80.50.60.6-0.60.6
Pavlov. Cond. lever contacts0.10.10.20.2-0.20.50.20.20.2-0.20.2
Pavlov. Cond. magazine entry number1.21.51.8-1.2-0.9-1.4-1.2-1.2-1.21.2-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.1-0.50.0-0.3-0.3-0.30.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.00.70.31.00.70.70.8-0.70.7
Pavlov. Cond. response bias0.50.60.70.80.50.80.70.80.8-0.80.8
Bone: apparent density0.50.91.01.01.00.81.01.01.0-1.01.0
Bone surface0.00.10.1-0.2-0.2-0.4-0.3-0.3-0.30.3-0.3
Bone volume0.00.00.00.10.0-0.00.00.00.0-0.00.0
Bone: connectivity density1.11.71.81.31.31.21.31.31.3-1.31.3
Bone: cortical apparent density0.50.60.60.80.80.70.80.80.8-0.80.8
Bone: cortical area0.00.10.20.2-0.00.50.20.20.2-0.20.2
Bone: cortical porosity0.40.50.60.80.60.40.70.70.7-0.70.7
Bone: cortical porosity1.41.51.71.31.11.01.31.31.3-1.31.3
Bone: cortical thickness1.42.32.71.51.31.61.51.51.5-1.51.5
Bone: cortical thickness1.31.52.71.20.81.61.21.21.2-1.21.2
Bone: cortical tissue density0.50.60.60.80.80.70.80.80.8-0.80.8
Bone: elastic displacement0.40.50.7-0.7-0.6-0.8-0.7-0.7-0.70.7-0.7
Bone: elastic work0.00.00.0-0.0-0.10.1-0.1-0.1-0.00.0-0.0
Bone: endosteal estimation2.04.44.7-2.2-2.1-1.7-2.2-2.2-2.12.1-2.1
Bone: endosteal perimeter3.16.37.0-2.6-2.6-1.9-2.6-2.6-2.62.6-2.6
Bone: final force0.30.51.1-0.6-1.0-0.0-0.7-0.7-0.70.7-0.7
Bone: final moment0.10.10.4-0.2-0.60.3-0.3-0.3-0.30.3-0.3
Bone: marrow area2.14.54.8-2.2-2.2-1.7-2.2-2.2-2.22.2-2.2
Bone: maximum diameter1.73.13.8-1.8-2.0-1.1-1.8-1.8-1.81.8-1.8
Bone: maximum force0.40.71.0-0.8-1.0-0.4-0.9-0.9-0.80.8-0.8
Bone: maximum moment0.10.20.4-0.4-0.6-0.2-0.5-0.5-0.50.5-0.5
Bone: minimum diameter0.00.00.00.00.1-0.10.00.00.0-0.00.0
Bone: periosteal estimation1.12.22.8-1.5-1.7-1.0-1.6-1.5-1.51.5-1.5
Bone: periosteal perimeter1.72.83.4-1.7-1.9-1.1-1.7-1.7-1.71.7-1.7
Bone: post-yield work0.10.20.3-0.4-0.3-0.6-0.4-0.4-0.40.4-0.4
Bone: stiffness1.21.92.0-1.3-1.4-1.2-1.4-1.4-1.41.4-1.4
Bone: tissue strength1.41.31.51.21.20.81.21.21.2-1.21.2
Bone: trabecular number1.82.72.81.71.61.51.71.71.7-1.71.7
Bone: trabecular spacing0.00.00.0-0.1-0.2-0.0-0.1-0.1-0.10.1-0.1
Bone: trabecular thickness0.30.30.40.50.70.50.60.60.6-0.60.6
Bone: trabecular tissue density5.17.18.3-2.7-2.9-2.2-2.7-2.7-2.72.7-2.7
Breakpoint value in progressive ratio session0.40.40.5-0.6-0.7-0.7-0.6-0.6-0.60.6-0.6
Distance traveled before self-admin0.50.52.0-0.80.3-1.4-0.5-0.5-0.60.6-0.6
Distance traveled after self-admin1.51.72.0-1.4-0.9-1.4-1.3-1.3-1.41.3-1.3
Delta time in closed arm before/after self-admin0.10.10.10.30.10.10.30.30.3-0.30.3
Delta time in open arm before/after self-admin1.11.01.81.00.81.31.01.01.0-1.01.0
Diff in mean of infusions in LGA sessions1.51.72.9-1.3-0.8-1.7-1.2-1.3-1.31.3-1.3
Extinction: sum of active levers before priming0.10.10.20.10.3-0.50.10.10.1-0.10.1
Active lever presses in extinction session 60.20.20.9-0.20.5-0.9-0.1-0.1-0.10.1-0.1
Delta distance traveled before/after self-admin0.70.71.5-0.7-1.2-0.1-0.9-0.8-0.80.8-0.8
Delta ambulatory time before/after self-admin0.20.20.7-0.3-0.80.1-0.5-0.4-0.40.4-0.4
Time in closed arm before self-admin0.10.10.6-0.10.7-0.70.0-0.0-0.00.0-0.0
Time in closed arm after self-admin0.10.10.5-0.10.5-0.70.10.0-0.00.00.0
Time in open arm before self-admin0.80.91.5-0.9-1.2-0.9-0.9-0.9-0.90.9-0.9
Time in open arm after self-admin0.10.10.40.2-0.40.70.10.10.1-0.10.1
Sum of active levers in priming session hrs 5-60.00.00.2-0.1-0.1-0.5-0.1-0.1-0.10.1-0.1
Time to tail flick, vehicle, before self-admin0.10.10.40.4-0.00.60.30.30.4-0.30.3
Time to tail flick, vehicle, after self-admin0.10.10.5-0.10.7-0.60.10.10.0-0.00.1
Time to tail flick, test, before self-admin0.90.91.01.00.91.00.91.01.0-0.90.9
Time to tail flick, test, after self-admin1.01.03.20.81.8-0.60.90.90.8-0.80.9
Delta time to tail flick, vehicle, before/after SA0.10.10.50.00.7-0.50.20.20.1-0.10.2
Delta time to tail flick, test, before/after SA0.20.21.0-0.40.2-1.0-0.2-0.3-0.30.3-0.3
Ambulatory time before self-admin0.10.10.3-0.10.5-0.40.10.0-0.0-0.00.0
Ambulatory time after self-admin0.40.50.6-0.8-0.6-0.5-0.7-0.7-0.70.7-0.7
Total heroin consumption2.53.04.4-1.7-1.3-2.1-1.7-1.7-1.71.7-1.7
Area under the delay curve0.20.21.0-0.30.3-1.0-0.2-0.2-0.30.3-0.3
Delay disc. indifference point, 0s delay0.10.10.30.20.60.20.30.30.3-0.30.3
Delay disc. indifference point, 16s delay0.10.10.6-0.10.6-0.80.10.0-0.00.00.0
Delay disc. indifference point, 2s delay0.10.10.7-0.10.5-0.8-0.0-0.1-0.10.1-0.1
Delay disc. indifference point, 24s delay0.10.10.40.30.7-0.00.40.40.3-0.30.3
Delay disc. indifference point, 4s delay0.20.20.9-0.10.6-1.00.0-0.0-0.10.1-0.1
Delay disc. indifference point, 8s delay0.20.20.8-0.4-0.1-0.9-0.4-0.4-0.40.4-0.4
Delay discount exponential model param0.30.31.50.5-0.21.20.40.40.4-0.40.4
Delay discount hyperbolic model param0.20.21.30.3-0.41.10.20.30.3-0.30.3
Fecal boli incidents, locomotor time 10.00.00.0-0.00.1-0.0-0.0-0.0-0.00.0-0.0
Change in fecal boli incidents, locomotor task0.10.10.4-0.1-0.40.6-0.1-0.1-0.10.1-0.1
Time >=10cm from walls, locomotor time 10.10.10.2-0.5-0.3-0.2-0.4-0.4-0.40.4-0.4
Bouts of movement, locomotor time 10.10.10.2-0.3-0.50.4-0.3-0.3-0.20.3-0.3
Total resting periods, locomotor time 10.10.10.2-0.3-0.40.4-0.3-0.2-0.20.2-0.2
Rest time, locomotor task time 10.10.10.60.10.00.80.10.10.2-0.20.2
Distance moved, locomotor task time 10.10.10.10.30.3-0.20.30.30.3-0.30.3
Vertical activity count, locomotor time 10.10.10.30.20.5-0.50.20.20.2-0.20.2
Time >=10cm from walls, locomotor time 20.10.10.50.2-0.20.70.10.20.2-0.20.2
Bouts of movement, locomotor time 22.02.22.7-1.7-1.1-1.5-1.5-1.5-1.51.5-1.5
Total resting periods, locomotor time 22.22.43.0-1.7-1.2-1.6-1.6-1.6-1.61.6-1.6
Rest time, locomotor task time 20.20.30.70.40.40.80.40.50.5-0.50.5
Distance moved, locomotor task time 20.00.00.10.30.10.10.20.20.2-0.20.2
Vertical activity count, locomotor time 20.30.30.90.51.0-0.40.50.50.5-0.50.5
Weight adjusted by age6.06.77.1-2.7-2.6-2.2-2.6-2.6-2.62.6-2.6
Seeking ratio, delayed vs. immediate footshock0.70.80.8-0.8-0.9-0.9-0.9-0.9-0.90.9-0.9
Locomotion in novel chamber0.70.91.40.91.20.60.90.90.9-0.90.9
Locomotion in novel chamber post-restriction0.30.30.50.60.70.30.60.60.6-0.60.6
Progressive ratio0.40.51.20.51.1-0.10.70.70.6-0.60.6
Food seeking constrained by brief footshock0.50.60.8-0.8-0.9-0.7-0.8-0.8-0.80.8-0.8
Seeking ratio, punishment vs. effort2.53.15.6-1.6-2.4-0.7-1.9-1.8-1.81.8-1.8
Run reversals in cocaine runway, females0.00.00.0-0.10.00.0-0.0-0.0-0.00.0-0.0
Run reversals in cocaine runway, males0.00.00.20.0-0.20.5-0.0-0.00.0-0.00.0
Latency to leave start box in cocaine runway2.93.13.3-1.8-1.5-1.8-1.8-1.8-1.81.8-1.8
Latency to leave start box in cocaine runway, F0.60.71.1-0.8-0.6-1.0-0.8-0.8-0.80.8-0.8
Latency to leave start box in cocaine runway, M3.93.84.3-2.1-1.7-1.8-2.0-2.0-2.02.0-2.0
Cd content in liver0.10.10.30.20.60.20.30.30.3-0.30.3
Co content in liver0.10.10.50.30.10.70.30.30.3-0.30.3
Cu content in liver0.20.20.5-0.4-0.70.4-0.4-0.4-0.40.4-0.4
Fe content in liver0.40.50.60.70.70.80.70.70.7-0.70.7
K content in liver2.12.12.5-1.5-1.6-1.0-1.5-1.5-1.51.5-1.5
Mg content in liver3.63.84.1-2.0-2.0-1.6-2.0-2.0-2.02.0-2.0
Mn content in liver0.00.00.0-0.2-0.1-0.0-0.1-0.1-0.10.1-0.1
Na content in liver2.02.13.7-1.4-1.9-0.5-1.5-1.5-1.51.5-1.5
Rb content in liver1.72.12.2-1.5-1.3-1.4-1.5-1.5-1.51.5-1.5
Se content in liver0.30.40.50.60.70.60.60.60.6-0.60.6
Sr content in liver0.00.00.00.2-0.0-0.00.10.10.1-0.10.1
Zn content in liver0.30.40.50.60.50.70.60.60.6-0.60.6