Hub : Genes

Hectd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000056753 0.14 0.06 5.1e-13 0.08 0.1 0.11 0.1 2.5e-09 1.0e-11 3.4e-12 1.0e-11
2 Adipose mRNA stability ENSRNOG00000056753 0.03 0.02 8.7e-04 0.01 0.02 0.02 0.01 9.8e-03 2.8e-03 6.3e-03 1.6e-02
3 BLA gene expression ENSRNOG00000056753 0.19 0.08 2.3e-09 0.14 0.17 0.17 0.17 7.0e-08 1.9e-09 3.4e-09 1.1e-09
4 Brain gene expression ENSRNOG00000056753 0.2 0.08 5.6e-17 0.19 0.2 0.21 0.2 5.2e-17 7.2e-18 5.0e-19 2.6e-18
5 Brain intron excision ratio chr1:234328907:234331775 0.05 0.04 9.8e-03 0.01 0.01 0.01 0.01 2.3e-02 1.6e-02 4.1e-02 4.3e-02
6 Brain intron excision ratio chr1:234328907:234331784 0.05 0.04 8.6e-03 0.01 0.01 0.02 0.01 1.7e-02 1.4e-02 4.4e-03 3.7e-02
7 Brain mRNA stability ENSRNOG00000056753 0.04 0.02 6.9e-04 0.02 0.01 0 0.01 3.6e-03 2.2e-02 1.2e-01 7.0e-02
8 IL gene expression ENSRNOG00000056753 0.44 0.13 2.0e-07 0.16 0.24 0.19 0.18 1.3e-04 2.2e-06 2.8e-05 3.7e-05
9 LHb gene expression ENSRNOG00000056753 0.25 0.13 6.4e-04 0.08 0.07 0.08 0.09 5.7e-03 7.5e-03 5.1e-03 4.7e-03
10 Liver gene expression ENSRNOG00000056753 0.06 0.04 1.4e-05 0.05 0.05 0.04 0.05 1.1e-06 7.8e-06 7.9e-06 2.1e-06
11 NAcc gene expression ENSRNOG00000056753 0.07 0.04 5.6e-05 0.05 0.07 0.06 0.06 1.7e-04 1.0e-05 3.0e-05 3.6e-05
12 NAcc mRNA stability ENSRNOG00000056753 0.1 0.05 2.5e-06 0.07 0.07 0.09 0.08 7.1e-06 5.9e-06 5.6e-07 1.8e-06
13 OFC gene expression ENSRNOG00000056753 0.3 0.14 3.3e-04 0.12 0.16 0.1 0.13 9.9e-04 1.0e-04 2.8e-03 5.5e-04
14 PL gene expression ENSRNOG00000056753 0.2 0.09 3.7e-10 0.09 0.14 0.07 0.12 5.3e-07 2.0e-10 2.6e-06 1.9e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.10.42.00.9-0.2-0.30.3-0.81.4-0.80.2-0.40.70.0-0.50.20.0
BMI without tail0.10.31.70.0-0.5-0.9-0.00.20.5-1.3-0.3-0.60.3-0.6-0.30.20.0
Body weight1.46.113.2-1.9-2.9-3.3-1.4-1.22.4-3.6-2.8-2.9-0.7-3.40.6-1.7-2.8
Epididymis fat weight0.92.15.9-1.4-1.1-2.4-1.3-0.31.7-1.8-1.6-1.1-1.0-1.40.8-1.4-1.6
Glucose0.10.10.3-0.40.0-0.4-0.3-0.2-0.2-0.1-0.2-0.3-0.5-0.00.3-0.4-0.6
Heart weight0.30.41.00.30.8-1.00.11.0-0.20.70.70.70.30.5-0.40.80.4
Left kidney weight1.33.89.2-1.8-1.4-3.0-1.6-0.02.2-2.0-2.3-1.8-1.5-2.01.6-1.9-2.6
Right kidney weight1.33.614.5-2.2-0.6-3.8-1.81.21.1-0.9-2.1-0.9-1.8-1.62.1-1.9-2.4
Tail length1.85.511.1-3.0-2.7-2.7-2.00.20.4-2.9-3.0-2.6-1.8-3.31.4-1.8-2.4
Length with tail2.710.021.8-3.7-3.7-3.7-2.4-0.31.3-3.9-4.1-3.6-1.8-4.71.6-2.5-3.7
Length without tail2.75.810.4-2.4-2.7-1.9-1.8-1.52.1-2.6-3.1-2.8-1.5-3.21.4-2.5-3.2
Liver weight, left3.04.88.2-2.1-2.6-1.6-1.7-1.82.3-2.6-2.6-2.7-1.1-2.90.9-1.9-2.8
Liver weight, right2.23.66.3-2.2-1.8-2.2-1.7-0.41.4-1.5-2.5-1.9-1.4-2.31.5-2.2-2.4
Parametrial fat weight0.91.93.7-1.3-1.3-1.9-1.2-0.30.6-1.4-1.8-1.5-0.8-1.61.0-1.5-1.7
Retroperitoneal fat weight0.31.13.3-0.6-0.9-1.7-0.7-0.61.8-1.6-1.0-1.1-0.4-1.10.3-0.6-1.0
Intraocular pressure0.20.31.00.1-0.5-1.00.5-0.30.2-0.9-0.1-0.70.7-0.7-0.80.4-0.2
Extensor digitorum longus weight1.14.56.4-2.3-2.0-2.0-1.8-1.81.9-1.7-2.4-2.5-2.3-2.01.9-2.5-2.5
Soleus weight0.41.33.11.3-0.71.61.3-1.40.3-0.40.9-0.51.6-0.3-1.81.40.5
Tibialis anterior weight1.44.87.5-2.2-2.5-1.6-1.6-2.31.9-1.8-2.6-2.7-2.1-2.31.7-2.6-2.4
Tibia length0.10.41.0-0.8-0.7-0.5-0.40.30.6-0.9-0.8-0.6-0.2-1.00.3-0.2-0.7
Number of licking bursts0.80.93.0-0.61.3-1.2-0.61.7-0.31.2-0.40.8-1.00.71.0-0.9-0.2
Food consumed during 24 hour testing period0.20.31.6-0.60.2-1.3-0.60.80.00.3-0.40.0-0.6-0.20.5-0.4-0.5
Times rat made contact with spout0.60.61.4-0.8-1.0-0.6-0.7-0.30.2-0.8-1.2-0.9-0.6-1.10.5-1.0-0.7
Mean time between licks in bursts1.01.43.60.61.90.40.51.3-0.71.61.41.6-0.01.8-0.20.91.2
Mean num. licks in bursts0.80.93.30.2-1.70.90.3-1.80.5-1.4-0.3-1.20.6-1.2-0.60.3-0.2
Std. dev. time between licks in bursts1.51.85.20.72.3-0.10.21.8-1.02.01.31.9-0.12.10.10.61.1
Water consumed over 24 hours0.91.12.7-1.3-0.5-1.0-1.0-0.00.30.2-1.3-0.8-1.6-0.71.3-1.6-1.0
Indifference point 0 sec0.30.53.4-0.10.0-1.9-0.31.40.3-0.4-0.50.10.4-0.60.0-0.1-0.4
Indifference point AUC1.31.55.3-1.50.0-1.9-1.12.0-2.30.4-0.80.5-1.2-0.31.4-0.60.0
Indifference point function ln k1.31.810.00.9-0.80.90.6-2.43.2-1.4-0.2-1.50.8-0.6-0.9-0.1-0.9
Indifference point function log k1.31.810.00.9-0.80.90.6-2.43.2-1.4-0.2-1.50.8-0.6-0.9-0.1-0.9
Delay discounting total patch changes 0 sec0.30.53.1-0.10.0-1.8-0.31.40.4-0.5-0.50.00.4-0.60.0-0.0-0.4
Delay discounting total patch changes 12 sec1.01.46.6-0.31.0-1.3-0.32.6-2.01.40.21.5-0.30.50.40.30.9
Delay discounting total patch changes 18 sec0.30.42.2-0.30.0-1.5-0.21.5-0.7-0.4-0.50.0-0.0-0.40.4-0.2-0.0
Delay discounting total patch changes 24 sec1.21.57.2-1.5-0.4-2.7-1.01.6-1.0-0.6-1.3-0.4-0.9-1.11.1-1.0-0.9
Delay discounting total patch changes 6 sec1.01.68.8-0.80.7-2.0-0.63.0-2.20.8-0.21.2-0.30.00.60.10.4
Delay discounting time to switch 0 sec0.60.92.70.81.60.80.60.5-0.01.61.01.1-0.11.6-0.10.30.8
Delay discounting water rate 0 sec0.40.62.0-0.2-1.0-0.8-0.5-0.71.3-1.4-0.7-0.8-0.0-0.90.2-0.4-0.7
Delay discounting water rate 12 sec0.20.40.9-0.4-0.7-0.5-0.3-0.30.7-0.9-0.7-0.50.0-1.0-0.1-0.3-0.9
Delay discounting water rate 18 sec0.70.92.2-0.8-1.2-0.5-0.6-1.01.5-1.3-0.9-0.9-0.3-1.3-0.0-0.6-1.2
Delay discounting water rate 24 sec1.92.75.1-1.8-2.1-1.3-1.3-1.11.1-2.1-2.0-1.9-1.0-2.30.7-1.3-1.9
Delay discounting water rate 6 sec0.10.10.30.5-0.0-0.20.5-0.30.3-0.20.3-0.10.50.0-0.50.40.1
Locomotor activity0.20.30.90.71.0-0.20.40.71.00.30.40.50.10.8-0.10.20.4
Locomotor testing distance0.40.72.00.91.4-0.10.41.10.90.70.71.20.21.2-0.10.40.6
Locomotor testing rearing0.30.42.90.0-0.3-0.4-0.4-0.61.7-0.7-0.6-0.5-0.3-0.40.3-0.6-0.7
Light reinforcement 10.40.82.91.1-0.20.21.4-0.5-0.2-0.30.6-0.21.7-0.2-1.61.00.6
Light reinforcement 22.93.87.31.72.11.11.51.5-2.72.32.22.31.42.2-1.31.72.5
Reaction time number correct0.50.72.10.0-1.41.00.6-1.5-0.2-0.8-0.4-1.10.7-1.2-1.00.0-0.4
Reaction time mean minus median0.70.91.81.30.80.60.80.10.80.21.21.01.20.9-1.11.30.8
Reaction time mean minus median AUC0.71.02.11.20.90.40.80.50.5-0.11.31.21.11.0-1.11.51.2
Reaction time num false alarms1.52.13.3-1.5-1.5-1.5-1.0-1.01.2-1.4-1.8-1.8-1.1-1.71.1-1.6-1.8
Reaction time num false alarms AUC1.31.83.0-1.4-1.1-1.7-1.1-0.51.1-1.1-1.7-1.4-1.3-1.41.3-1.6-1.7
Reaction time trials correct on left0.50.72.10.0-1.41.00.6-1.5-0.2-0.8-0.4-1.10.7-1.2-1.00.0-0.4
Reaction time trials on left0.50.72.0-0.0-1.41.00.5-1.4-0.2-0.8-0.4-1.10.6-1.2-0.90.0-0.4
Reaction time mean1.52.15.81.02.40.50.41.7-0.61.91.62.20.12.40.20.91.3
Reaction time mean AUC2.12.87.31.22.70.50.51.8-0.72.21.92.50.12.70.11.11.6
Median of all reaction times2.12.87.61.02.70.70.51.8-1.02.41.82.4-0.02.70.30.91.6
Reaction time omissions0.10.10.4-0.20.2-0.0-0.20.40.4-0.6-0.10.1-0.10.20.30.1-0.0
Reaction time false alarm rate1.01.43.3-1.2-0.6-1.8-1.1-0.11.4-0.9-1.3-0.9-1.3-0.81.4-1.4-1.4
Reaction time premature initiation rate0.50.61.8-0.7-1.2-0.0-0.4-0.80.5-0.8-1.0-0.9-0.1-1.3-0.1-0.6-1.2
Reaction time premature initiations1.11.64.6-0.7-2.10.4-0.1-1.60.5-1.4-1.3-1.60.3-2.2-0.6-0.6-1.5
Std. dev. reaction times0.81.12.51.01.40.30.51.2-0.10.71.31.60.71.4-0.61.31.1
Reaction time trials completed0.50.72.0-0.0-1.41.00.5-1.4-0.2-0.8-0.4-1.10.6-1.2-0.90.0-0.4
Reaction time trials AUC0.40.61.7-0.1-1.30.90.4-1.3-0.3-0.6-0.5-1.00.4-1.1-0.7-0.2-0.4
Social response proportion1.61.74.11.80.62.01.3-0.90.70.81.60.61.41.1-1.81.41.4
Social responses1.21.54.21.80.11.01.7-0.60.40.51.30.42.00.3-2.01.61.0
Social time0.30.52.00.20.9-0.7-0.11.4-0.61.00.20.90.10.60.30.00.4
Conditioned locomotion0.40.51.8-0.2-0.80.40.2-1.31.3-0.5-0.5-1.1-0.1-0.7-0.2-0.5-0.8
Cocaine response after cond. corrected0.10.20.50.1-0.40.40.10.4-0.5-0.7-0.10.10.6-0.4-0.40.50.4
Cocaine response after cond. not corrected0.50.61.5-1.0-1.1-0.4-0.80.2-0.5-1.2-1.1-0.6-0.3-1.20.4-0.4-0.5
Cocaine response before conditioning1.21.53.5-1.9-0.6-1.6-1.40.6-1.0-0.2-1.4-0.5-1.5-1.01.6-1.4-1.2
Saline control response0.50.61.2-1.0-1.10.0-1.0-0.0-0.6-0.6-1.1-0.6-0.9-1.00.8-0.9-0.3
Condit. Reinf. active minus inactive responses2.12.64.5-1.8-1.5-1.5-1.7-0.91.1-2.1-1.9-1.8-1.5-1.61.3-1.7-1.7
Condit. Reinf. active-inactive response ratio0.70.71.5-1.1-0.7-1.0-0.8-0.50.4-1.2-1.0-1.0-0.8-0.70.8-0.9-0.8
Condit. Reinf. active responses2.23.17.8-1.9-2.4-1.1-1.5-1.20.8-2.8-2.1-2.3-0.9-2.40.7-1.2-1.8
Condit. Reinf. inactive responses0.91.13.3-0.9-1.7-0.3-0.8-0.6-0.0-1.7-1.2-1.3-0.0-1.8-0.0-0.3-1.0
Condit. Reinf. lever presses0.10.20.7-0.5-0.6-0.1-0.3-0.20.1-0.9-0.5-0.6-0.2-0.7-0.1-0.1-0.3
Condit. Reinf. lever reinforcers received1.72.45.9-1.7-2.0-1.0-1.4-1.00.8-2.4-1.8-1.9-0.9-2.00.7-1.1-1.5
Pavlov. Cond. lever latency0.20.31.3-0.2-0.1-0.3-0.3-1.01.10.0-0.3-0.5-0.6-0.00.5-0.8-0.7
Pavlov. Cond. magazine entry latency0.40.51.4-0.90.4-0.9-0.70.9-0.10.1-0.50.2-1.10.21.2-0.7-0.3
Pavlov. Cond. change in total contacts0.40.61.3-1.1-0.6-0.8-1.00.5-0.1-0.7-1.0-0.4-0.9-0.70.9-0.8-0.5
Pavlov. Cond. index score0.30.41.0-1.0-0.4-0.7-0.70.6-0.3-0.6-0.8-0.3-0.6-0.70.7-0.5-0.5
Pavlov. Cond. latency score0.30.40.8-0.9-0.6-0.6-0.60.4-0.1-0.8-0.8-0.5-0.5-0.80.6-0.5-0.5
Pavlov. Cond. lever contacts0.10.10.7-0.2-0.10.1-0.10.7-0.8-0.2-0.10.20.1-0.2-0.10.30.2
Pavlov. Cond. magazine entry number0.81.02.91.2-0.61.31.1-1.40.3-0.30.7-0.41.5-0.4-1.71.00.4
Pavlov. Cond. intertrial magazine entries1.31.62.9-1.2-1.6-0.9-1.0-1.20.8-1.6-1.6-1.7-0.7-1.70.4-1.2-1.6
Pavlov. Cond. lever-magazine prob. diff.0.50.61.5-1.2-0.4-0.9-0.90.7-0.2-0.7-1.0-0.3-0.9-0.71.0-0.8-0.6
Pavlov. Cond. response bias0.30.41.8-0.80.2-0.7-0.71.3-0.90.0-0.50.4-0.7-0.10.8-0.4-0.1
Conditioned reinforcement - actives0.80.82.40.1-1.40.30.7-0.80.8-1.0-0.6-1.01.1-1.6-0.90.1-0.8
Conditioned reinforcement - inactives1.01.12.91.0-1.11.11.0-1.21.0-0.80.2-1.01.7-1.0-1.60.8-0.1
Conditioned locomotion1.01.23.41.6-0.21.31.5-0.60.20.01.00.21.80.0-1.71.40.7
Intermittent access intake day 1-15 change1.31.34.21.7-0.50.51.4-0.91.5-0.30.7-0.32.0-0.4-1.91.20.2
Intermittent access intake escalation1.21.24.31.8-0.30.31.3-0.61.4-0.20.7-0.22.1-0.3-1.91.20.1
Intermittent access intake escalation 21.01.02.81.70.20.31.2-0.81.6-0.10.80.01.50.3-1.40.90.2
Intermitt. access day 1 inactive lever presses0.40.51.40.8-0.21.20.4-0.2-0.6-0.00.60.00.70.1-1.11.01.0
Intermitt. access day 15 inactive lever presses1.92.15.41.3-0.82.11.5-0.4-1.4-0.21.10.12.2-0.5-2.32.11.3
Intermitt. access escalation Index0.60.52.0-1.2-0.2-0.3-1.10.1-0.50.0-0.6-0.0-1.4-0.11.0-0.8-0.3
Intermittent access day 1 total infusions0.70.82.3-0.6-1.4-0.0-0.3-1.00.5-1.5-0.9-1.30.0-1.4-0.1-0.5-1.0
Intermittent access day 15 total infusions1.21.42.90.7-1.6-0.10.4-1.31.4-1.5-0.5-1.31.6-1.7-1.40.3-1.0
Intermittent access terminal intake (last 3 days)0.80.92.41.1-0.90.20.8-1.11.2-0.90.1-0.71.6-0.9-1.50.5-0.4
Intermittent access total infusions0.80.92.00.4-1.1-0.10.2-1.41.4-1.3-0.5-1.20.8-1.1-0.8-0.2-0.9
Intermittent access day 1 locomotion0.90.92.1-0.6-1.2-0.6-0.6-0.80.8-1.4-1.1-1.3-0.3-1.30.3-0.8-1.1
Intermittent access day 15 total locomotion0.80.82.31.4-0.40.61.0-0.90.8-0.40.7-0.31.5-0.3-1.51.00.3
Intermittent access total locomotion0.20.30.90.5-0.5-0.10.1-0.90.9-0.7-0.2-0.70.4-0.4-0.3-0.2-0.4
Intermittent access standard deviation0.40.51.60.9-0.40.50.4-0.71.0-0.40.5-0.11.0-0.3-1.30.80.0
Cocaine induced anxiety0.20.20.7-0.9-0.4-0.1-0.7-0.2-0.1-0.2-0.6-0.4-0.6-0.40.6-0.6-0.2
Post-drug Anxiety0.50.63.1-0.00.01.00.20.5-1.70.70.60.70.60.2-0.40.71.2
Baseline Anxiety0.50.61.10.60.40.71.00.5-1.00.60.80.70.70.4-0.71.00.9
Lifetime Intake0.50.61.60.3-0.9-0.00.4-1.11.3-1.1-0.3-0.90.7-1.0-0.8-0.0-0.7
Incentive Sensitization - Responses1.81.83.91.2-1.4-0.10.9-1.82.0-1.5-0.1-1.51.8-1.3-2.00.5-0.7
Incentive Sensitization - Breakpoint1.81.84.11.3-1.4-0.00.9-1.81.9-1.4-0.1-1.51.8-1.3-2.00.6-0.6
Progressive ratio test 1 active lever presses0.60.61.50.1-1.20.90.8-1.00.4-1.2-0.2-0.90.8-1.1-0.70.4-0.2
Progressive ratio test 1 breakpoint0.60.61.20.3-1.11.00.9-0.90.3-1.1-0.1-0.71.0-0.9-0.90.5-0.1
Progressive ratio test 1 inactive lever presses0.90.92.70.4-1.40.70.7-1.00.3-1.1-0.2-1.01.2-1.3-1.60.5-0.2
Progressive ratio test 2 active lever presses1.71.83.60.9-1.50.31.2-1.81.9-1.7-0.2-1.51.7-1.4-1.50.5-0.8
Progressive ratio test 2 breakpoint2.02.24.61.0-1.80.51.4-2.12.0-1.9-0.2-1.71.9-1.6-1.70.6-0.7
Progressive ratio test 2 inactive lever presses1.31.54.31.2-0.91.31.4-1.41.1-0.70.7-0.51.9-0.6-2.11.30.4
Total sessions with >9 infusions0.20.20.80.6-0.3-0.40.30.10.5-0.6-0.2-0.20.9-0.5-0.60.1-0.3
Short access day 1 total inactive lever presses2.52.88.92.20.02.11.9-0.70.00.21.70.32.40.4-3.02.21.7
Short access day 10 total inactive lever presses0.70.73.80.30.40.80.31.1-1.90.80.50.90.50.5-0.50.61.3
Short access day 1 total infusions0.00.00.3-0.20.1-0.10.00.50.3-0.1-0.10.2-0.1-0.2-0.20.1-0.0
Short access day 10 total infusions0.10.10.30.30.4-0.30.00.5-0.10.40.20.50.20.2-0.40.10.0
Short access total infusions0.20.30.70.0-0.7-0.00.2-0.30.6-0.7-0.3-0.50.5-0.9-0.7-0.0-0.5
Short access day 1 locomotion0.20.21.4-0.30.1-1.2-0.10.40.4-0.4-0.4-0.1-0.3-0.10.4-0.5-0.4
Short access day 10 total locomotion0.10.10.60.30.2-0.1-0.3-0.30.7-0.1-0.0-0.1-0.30.30.1-0.3-0.1
Short access total locomotion0.10.10.30.30.4-0.4-0.00.5-0.10.20.00.20.10.2-0.0-0.10.1
Compulsive drug intake1.41.43.7-1.4-1.8-0.7-0.8-0.9-0.4-1.3-1.4-1.9-0.4-1.80.3-0.8-1.2
One hour access (0.3 mA shock)2.63.05.70.5-2.40.41.1-2.32.0-2.1-0.6-2.21.9-2.4-2.10.4-1.2
One hour access (shock baseline)0.80.93.01.2-0.40.51.1-1.01.7-0.30.4-0.31.4-0.5-1.50.6-0.3
Number of responses in last shaping day0.70.72.40.8-0.90.71.1-0.80.2-0.70.2-0.71.5-0.8-1.40.80.0
Context. condit. distance diff. score2.02.46.1-0.8-2.0-0.6-0.7-2.51.7-2.4-1.3-2.3-0.6-1.60.3-1.0-1.5
Locomotion velocity, session 12.93.15.81.62.40.71.02.0-1.62.02.02.21.12.3-0.81.62.1
Locomotion distance, session 10.20.30.70.60.70.30.10.4-0.90.40.60.70.50.7-0.20.40.6
Locomotion velocity, session 20.40.41.40.61.2-0.00.10.9-0.50.60.70.80.11.10.20.40.7
Locomotion distance, session 20.40.61.4-0.70.3-1.2-1.20.40.6-0.2-0.7-0.0-1.00.11.2-1.0-0.7
Locomotion velocity, session 30.40.50.9-0.6-0.6-0.6-0.6-0.50.8-1.0-0.7-0.8-0.5-0.60.5-0.6-0.8
Locomotion distance, session 31.92.13.0-1.5-1.2-1.2-1.5-1.21.5-1.6-1.5-1.5-1.6-1.21.3-1.5-1.7
Stereotopy head waving bouts, day 31.01.22.11.30.61.11.10.4-1.10.41.20.81.40.8-1.21.51.4
Stereotopy head waving duration, day 30.91.12.01.10.31.21.30.4-1.20.51.10.61.40.5-1.31.31.4
Locomotion velocity, session 71.41.52.5-1.3-1.6-0.4-0.9-1.40.7-1.2-1.6-1.5-1.0-1.50.9-1.5-1.4
Locomotion distance, session 71.01.22.4-0.9-1.5-0.2-0.6-1.40.8-0.9-1.3-1.5-0.6-1.40.6-1.2-1.3
Stereotopy head waving bouts, day 70.10.20.40.20.40.10.20.6-0.6-0.10.40.50.20.4-0.20.60.6
Stereotopy head waving duration, day 70.30.41.30.40.50.40.40.8-0.70.10.80.70.50.5-0.61.10.8
Locomotion velocity, session 80.10.10.60.1-0.30.00.4-0.80.1-0.1-0.0-0.40.1-0.2-0.2-0.1-0.3
Locomotion distance, session 81.11.73.6-0.9-1.1-1.0-1.2-1.91.5-1.7-1.2-1.6-1.0-0.80.9-1.4-1.4
Degree of sensitization distance0.10.10.30.1-0.20.20.4-0.0-0.50.6-0.2-0.00.2-0.2-0.0-0.30.1
Degree of sensitization stereotypy0.10.10.3-0.00.10.1-0.00.4-0.4-0.20.30.30.10.1-0.20.60.2
Condit. Reinf. active minus inactive responses0.70.81.9-1.30.3-1.0-1.30.9-0.4-0.2-0.70.1-1.30.11.4-0.9-0.4
Condit. Reinf. active-inactive response ratio0.80.81.90.31.40.30.01.2-1.01.30.81.3-0.11.30.30.40.8
Condit. Reinf. active responses1.51.83.3-1.8-1.1-1.2-1.7-0.10.6-1.5-1.7-1.2-1.6-1.21.5-1.4-1.3
Condit. Reinf. inactive responses2.32.76.4-1.6-2.2-1.0-1.3-1.01.2-2.5-2.0-2.1-1.0-2.20.7-1.2-1.5
Incentive salience index mean1.82.25.0-2.0-0.1-1.9-2.10.90.2-0.7-1.5-0.3-2.1-0.42.2-1.7-1.1
Condit. Reinf. lever presses1.41.95.1-1.70.0-1.9-2.01.00.6-0.6-1.4-0.1-2.0-0.22.2-1.7-0.9
Time in familiar zone, hab. session 10.30.30.80.70.20.90.80.1-0.40.40.60.40.70.2-0.70.70.5
Time in novel zone, hab. session 10.20.20.5-0.20.7-0.6-0.10.5-0.10.70.00.3-0.50.60.6-0.4-0.0
Total zone transitions, hab. session 10.10.10.40.1-0.10.70.2-0.2-0.4-0.20.10.00.4-0.1-0.40.30.2
Total locomotion distance, hab. session 10.10.20.4-0.10.60.4-0.20.2-0.20.50.00.4-0.50.70.6-0.50.1
Locomotion velocity, hab. session 10.20.20.8-0.30.6-0.0-0.50.1-0.00.4-0.20.3-0.80.70.9-0.8-0.0
Time in familiar zone, hab. session 20.50.50.90.90.80.50.70.7-0.51.00.80.90.60.8-0.40.70.8
Time in novel zone, hab. session 20.00.00.1-0.2-0.10.20.1-0.1-0.1-0.00.1-0.1-0.0-0.0-0.20.20.1
Total zone transitions, hab. session 20.20.31.4-0.20.7-0.3-0.41.2-0.90.30.20.7-0.10.50.20.30.3
Total locomotion distance, hab. session 20.20.31.0-0.01.0-0.3-0.50.7-0.30.50.20.7-0.40.90.6-0.20.1
Locomotion velocity, hab. session 20.20.30.7-0.20.8-0.5-0.70.50.00.3-0.10.5-0.70.70.9-0.5-0.2
Novel to familiar place preference ratio0.40.40.90.2-0.90.10.6-0.80.4-0.9-0.3-0.70.9-0.9-0.90.1-0.1
Novelty place preference0.50.51.10.4-0.90.30.8-1.00.5-0.7-0.1-0.71.0-0.8-1.10.20.0
Time in novel zone, NPP test0.30.30.90.5-0.50.21.0-0.80.5-0.30.0-0.50.9-0.5-0.90.2-0.0
Total zone transitions, NPP test0.40.61.5-0.80.5-1.0-1.11.0-0.40.2-0.60.4-1.10.21.2-0.8-0.5
Total locomotion distance, NPP test0.40.61.4-0.60.9-0.9-0.90.9-0.50.2-0.30.6-1.10.71.2-0.80.0
Locomotion velocity, NPP test0.50.82.0-1.00.4-1.1-1.40.9-0.3-0.3-0.70.3-1.30.31.4-1.0-0.2
Pavlov. Cond. lever latency1.62.14.21.70.51.82.10.1-0.81.01.60.72.00.6-2.02.01.3
Pavlov. Cond. magazine entry latency1.21.54.4-1.20.7-1.6-1.81.00.40.3-0.80.4-1.90.52.1-1.4-0.9
Pavlov. Cond. change in total contacts1.21.33.5-1.30.7-1.4-1.91.3-0.20.1-0.70.6-1.60.41.9-1.0-0.5
Pavlov. Cond. index score2.63.47.1-2.2-0.4-2.4-2.70.31.1-0.9-2.0-0.7-2.6-0.72.7-2.4-1.8
Pavlov. Cond. latency score3.34.28.3-2.5-0.7-2.6-2.90.11.2-1.3-2.3-1.0-2.8-1.02.8-2.7-2.0
Pavlov. Cond. lever contacts2.32.75.9-2.0-0.4-2.0-2.40.30.9-0.9-1.8-0.5-2.3-0.62.4-2.1-1.5
Pavlov. Cond. magazine entry number0.60.82.20.9-0.51.31.3-0.6-0.7-0.20.6-0.21.4-0.3-1.51.00.8
Pavlov. Cond. intertrial magazine entries0.81.02.3-1.0-1.5-0.4-0.5-0.60.6-1.5-1.2-1.3-0.4-1.50.2-0.6-0.9
Pavlov. Cond. lever-magazine prob. diff.2.53.17.3-2.1-0.0-2.3-2.60.60.9-0.6-1.8-0.4-2.6-0.32.7-2.3-1.6
Pavlov. Cond. response bias1.01.23.2-1.00.9-1.4-1.61.00.40.5-0.50.6-1.70.61.8-1.1-0.7
Bone: apparent density2.74.510.10.9-2.91.91.7-2.70.5-2.6-0.1-2.22.8-2.7-3.21.6-0.3
Bone surface1.32.45.70.6-2.11.21.2-1.5-0.3-2.10.1-1.52.2-2.0-2.41.60.0
Bone volume1.93.17.90.1-2.80.90.9-2.20.6-2.7-0.7-2.41.7-2.7-2.00.8-0.9
Bone: connectivity density2.13.310.11.7-1.62.22.0-1.7-0.4-1.20.9-0.93.0-1.3-3.22.10.8
Bone: cortical apparent density0.91.22.40.71.40.70.61.5-1.11.41.11.50.11.5-0.10.71.5
Bone: cortical area2.84.39.8-1.8-2.8-1.4-1.4-1.51.8-3.1-2.3-2.7-0.8-3.00.6-1.3-2.4
Bone: cortical porosity0.10.10.60.40.6-0.00.30.00.40.70.20.3-0.20.60.3-0.20.1
Bone: cortical porosity0.10.10.50.20.1-0.20.1-0.20.70.2-0.0-0.1-0.20.10.2-0.2-0.2
Bone: cortical thickness1.72.84.7-2.2-1.5-2.0-1.80.20.7-2.1-2.1-1.4-1.6-2.01.4-1.5-1.8
Bone: cortical thickness0.60.71.4-1.2-0.2-1.0-0.90.50.4-0.9-1.0-0.4-1.1-0.51.1-1.0-0.7
Bone: cortical tissue density1.01.42.60.81.50.70.71.5-1.11.51.21.50.21.6-0.10.81.6
Bone: elastic displacement3.64.18.42.42.61.71.50.9-1.02.22.62.41.32.9-1.21.82.5
Bone: elastic work2.93.87.32.72.11.81.70.3-0.41.72.52.01.82.5-1.61.92.5
Bone: endosteal estimation1.53.37.80.6-2.71.10.8-2.81.5-2.4-0.5-2.41.9-2.4-1.90.8-0.9
Bone: endosteal perimeter1.63.49.70.8-2.41.30.8-3.12.1-2.3-0.2-2.12.0-2.0-2.20.9-0.8
Bone: final force0.61.02.5-0.8-1.4-1.0-0.5-0.60.7-1.6-1.1-1.4-0.2-1.60.2-0.5-1.3
Bone: final moment0.30.51.7-0.4-1.1-0.5-0.2-0.40.4-1.2-0.6-1.00.2-1.3-0.30.0-0.8
Bone: marrow area1.63.48.10.6-2.81.20.9-2.81.5-2.5-0.4-2.42.0-2.4-2.10.9-0.8
Bone: maximum diameter3.25.814.4-0.0-3.71.00.4-3.82.7-3.6-1.2-3.41.5-3.3-1.90.4-1.6
Bone: maximum force0.81.44.0-0.2-1.9-0.30.1-1.31.0-2.0-0.8-1.70.7-2.0-0.80.2-1.0
Bone: maximum moment0.61.02.60.2-1.50.10.4-1.00.6-1.6-0.3-1.31.1-1.6-1.10.7-0.6
Bone: minimum diameter2.85.111.6-0.8-3.4-0.5-0.5-3.12.9-3.4-1.7-3.20.5-3.3-0.7-0.4-2.4
Bone: periosteal estimation2.14.310.9-0.3-3.30.30.0-2.92.1-3.3-1.4-3.01.2-3.1-1.30.1-1.7
Bone: periosteal perimeter2.43.99.4-0.6-3.0-0.1-0.4-2.82.5-3.1-1.5-2.80.5-2.8-0.7-0.4-1.9
Bone: post-yield work1.92.67.3-1.5-2.3-1.6-0.9-0.60.6-2.4-1.8-2.1-0.1-2.70.2-0.6-1.9
Bone: stiffness2.54.07.5-1.8-2.6-1.7-1.2-1.81.8-2.4-2.2-2.7-1.0-2.70.7-1.5-2.5
Bone: tissue strength1.31.32.61.11.10.70.91.0-1.11.61.41.30.81.1-0.91.31.2
Bone: trabecular number2.03.09.11.1-2.11.71.7-1.80.3-1.70.4-1.42.6-2.0-3.01.80.2
Bone: trabecular spacing1.41.85.3-1.60.7-1.4-1.71.6-0.80.8-0.90.6-2.10.42.3-1.5-0.5
Bone: trabecular thickness1.31.63.20.6-1.71.01.2-1.70.6-1.4-0.1-1.41.6-1.6-1.80.8-0.5
Bone: trabecular tissue density1.01.43.70.2-1.70.60.3-1.91.6-1.7-0.6-1.70.5-1.4-0.8-0.0-0.5
Breakpoint value in progressive ratio session1.31.53.4-1.6-1.7-0.7-1.1-0.60.1-1.4-1.5-1.5-0.7-1.90.2-1.0-1.2
Distance traveled before self-admin0.30.41.3-0.6-0.2-0.7-0.6-0.10.0-0.4-0.7-0.3-0.9-0.11.2-0.9-0.5
Distance traveled after self-admin1.31.53.91.4-0.22.01.6-0.7-0.60.21.20.41.40.3-1.71.51.5
Delta time in closed arm before/after self-admin1.31.23.9-0.90.8-2.0-1.20.71.2-0.0-0.70.2-1.40.41.6-1.3-1.1
Delta time in open arm before/after self-admin0.40.31.4-0.1-0.81.20.2-0.7-1.0-0.50.0-0.20.2-0.4-0.30.40.7
Diff in mean of infusions in LGA sessions0.70.81.2-1.0-0.6-0.7-0.8-0.91.0-0.9-0.9-1.0-1.1-0.50.7-1.0-1.1
Extinction: sum of active levers before priming0.60.61.1-1.1-0.8-0.4-0.7-0.20.0-0.6-1.0-0.8-0.7-0.90.7-0.8-1.0
Active lever presses in extinction session 61.11.12.6-0.7-1.60.3-0.4-1.40.9-1.5-1.0-1.4-0.2-1.5-0.3-0.6-0.8
Delta distance traveled before/after self-admin1.11.24.11.0-0.81.61.3-1.10.1-0.40.8-0.31.4-0.4-2.01.30.8
Delta ambulatory time before/after self-admin1.31.44.20.7-1.41.71.2-1.50.1-1.00.4-0.91.4-1.0-2.11.30.6
Time in closed arm before self-admin0.20.30.90.20.20.90.40.0-0.40.70.50.40.00.3-0.70.40.8
Time in closed arm after self-admin1.31.34.3-1.70.3-1.2-1.40.80.10.2-1.00.1-2.1-0.01.7-1.5-0.8
Time in open arm before self-admin0.20.20.70.80.6-0.80.50.3-0.0-0.10.3-0.00.80.4-0.10.2-0.0
Time in open arm after self-admin0.80.93.11.2-0.71.11.0-0.9-0.3-0.70.4-0.51.8-0.5-1.41.00.5
Sum of active levers in priming session hrs 5-61.41.42.80.80.71.60.90.8-1.21.51.31.40.70.8-1.11.41.7
Time to tail flick, vehicle, before self-admin1.01.02.01.11.00.61.00.7-0.81.01.21.10.91.1-0.91.01.4
Time to tail flick, vehicle, after self-admin2.12.34.2-1.5-1.6-0.8-1.3-1.01.0-1.6-2.0-1.8-1.2-1.81.0-2.0-2.0
Time to tail flick, test, before self-admin1.81.74.5-0.6-1.90.3-0.3-2.11.4-1.7-1.2-2.1-0.3-1.6-0.0-0.9-1.3
Time to tail flick, test, after self-admin0.10.21.3-0.2-0.1-0.4-0.00.6-1.10.2-0.20.10.1-0.20.2-0.10.3
Delta time to tail flick, vehicle, before/after SA6.05.89.3-2.3-2.7-1.1-2.0-2.02.1-2.8-3.0-3.0-1.8-2.91.5-2.6-3.0
Delta time to tail flick, test, before/after SA0.20.21.0-0.20.2-1.0-0.30.8-0.70.3-0.20.40.0-0.00.3-0.20.1
Ambulatory time before self-admin0.30.31.4-0.20.5-0.7-0.50.3-0.00.2-0.20.3-0.80.61.2-0.7-0.1
Ambulatory time after self-admin1.11.22.81.4-0.51.71.5-1.3-0.0-0.40.8-0.31.30.1-1.61.11.1
Total heroin consumption0.40.51.9-0.4-1.30.2-0.1-0.60.2-0.8-0.7-1.00.3-1.4-0.3-0.2-0.6
Area under the delay curve1.21.25.6-1.6-0.7-1.1-0.81.5-2.4-0.5-1.2-0.2-0.6-1.10.8-0.7-0.3
Delay disc. indifference point, 0s delay2.02.14.0-1.8-1.6-1.5-1.1-0.4-0.2-1.6-2.0-1.6-1.3-1.81.2-1.8-1.4
Delay disc. indifference point, 16s delay0.70.73.9-1.0-1.0-0.1-0.20.8-2.0-0.6-0.7-0.30.2-1.3-0.20.1-0.0
Delay disc. indifference point, 2s delay0.30.32.7-0.2-0.30.10.10.7-1.60.0-0.10.20.5-0.4-0.40.30.6
Delay disc. indifference point, 24s delay2.02.06.0-2.1-0.4-1.4-1.51.6-2.5-0.4-1.4-0.2-1.5-0.81.7-1.2-0.7
Delay disc. indifference point, 4s delay1.51.63.3-1.8-1.1-1.3-1.00.7-1.6-1.0-1.7-0.9-0.9-1.51.2-1.3-1.0
Delay disc. indifference point, 8s delay1.51.610.4-1.20.5-0.8-0.62.5-3.20.9-0.40.9-0.6-0.00.7-0.20.6
Delay discount exponential model param1.21.35.91.70.61.10.9-1.62.40.41.20.20.61.1-0.90.70.4
Delay discount hyperbolic model param1.01.16.31.50.50.90.7-1.62.50.31.00.00.40.9-0.70.50.1
Fecal boli incidents, locomotor time 10.10.10.50.2-0.3-0.20.2-0.7-0.30.3-0.1-0.2-0.1-0.00.2-0.4-0.1
Change in fecal boli incidents, locomotor task0.10.10.3-0.50.1-0.1-0.40.6-0.30.2-0.10.2-0.3-0.00.30.0-0.0
Time >=10cm from walls, locomotor time 14.14.16.9-2.3-2.6-0.6-1.8-1.91.1-2.3-2.3-2.6-1.6-2.61.1-1.7-2.5
Bouts of movement, locomotor time 10.50.64.10.4-0.4-0.40.4-0.62.0-0.3-0.5-0.80.5-0.6-0.2-0.5-0.9
Total resting periods, locomotor time 10.50.63.00.0-0.7-0.40.2-0.61.7-0.4-0.8-0.90.4-1.0-0.1-0.6-0.9
Rest time, locomotor task time 10.70.71.31.20.30.91.1-0.20.90.90.80.61.10.4-1.10.80.8
Distance moved, locomotor task time 12.12.25.3-2.3-0.7-1.5-1.80.5-1.7-1.2-1.6-0.7-2.2-0.91.8-1.5-1.2
Vertical activity count, locomotor time 10.20.20.5-0.7-0.1-0.5-0.40.1-0.5-0.4-0.5-0.4-0.7-0.20.6-0.4-0.6
Time >=10cm from walls, locomotor time 22.32.45.6-2.4-1.6-1.3-1.6-0.1-0.8-1.4-1.9-1.5-1.8-1.81.5-1.6-1.5
Bouts of movement, locomotor time 20.50.51.7-0.11.0-1.0-0.01.3-0.80.8-0.10.7-0.30.70.8-0.70.2
Total resting periods, locomotor time 20.50.51.7-0.21.0-1.1-0.11.3-0.60.9-0.30.6-0.40.60.9-0.90.0
Rest time, locomotor task time 20.40.42.6-0.10.1-0.60.2-0.21.60.4-0.6-0.4-0.3-0.20.5-1.0-1.0
Distance moved, locomotor task time 20.91.12.5-1.6-1.0-0.8-1.4-0.1-0.7-1.4-1.1-0.7-1.4-0.81.1-0.8-0.7
Vertical activity count, locomotor time 20.50.54.0-0.00.40.00.10.9-2.00.70.40.70.10.40.00.50.7
Weight adjusted by age0.50.61.30.70.01.10.80.2-0.70.10.60.41.00.1-1.20.91.1
Seeking ratio, delayed vs. immediate footshock0.20.20.8-0.1-0.0-0.5-0.1-0.80.9-0.1-0.2-0.7-0.40.10.5-0.6-0.6
Locomotion in novel chamber1.62.09.21.5-0.51.41.1-2.53.0-1.00.6-1.01.10.1-1.50.60.0
Locomotion in novel chamber post-restriction2.93.48.8-1.3-2.3-0.7-0.9-2.22.1-3.0-1.9-2.5-0.8-2.20.4-1.4-2.1
Progressive ratio1.31.52.7-0.8-0.8-1.2-1.3-1.11.5-1.5-1.2-1.4-1.1-0.81.0-1.4-1.6
Food seeking constrained by brief footshock1.41.74.1-0.6-1.1-1.0-0.9-1.51.9-1.7-1.2-1.7-0.4-1.30.3-1.0-2.0
Seeking ratio, punishment vs. effort0.10.10.5-0.20.00.00.30.6-0.70.40.00.20.2-0.2-0.10.30.0
Run reversals in cocaine runway, females0.80.81.61.30.81.10.80.10.60.51.10.80.90.9-1.01.11.1
Run reversals in cocaine runway, males0.30.31.1-0.60.2-1.0-0.60.6-0.3-0.3-0.50.1-0.6-0.10.7-0.6-0.6
Latency to leave start box in cocaine runway0.91.04.4-0.1-1.20.30.0-1.61.2-2.1-0.6-1.60.3-0.8-0.1-0.2-0.5
Latency to leave start box in cocaine runway, F0.50.52.40.0-0.7-0.00.0-1.11.2-1.5-0.4-1.1-0.1-0.30.1-0.3-0.3
Latency to leave start box in cocaine runway, M0.60.62.0-0.3-1.10.1-0.2-0.90.4-1.4-0.7-1.20.4-1.1-0.1-0.2-0.7
Cd content in liver0.20.21.60.00.5-0.3-0.21.3-0.30.50.30.70.10.30.20.40.3
Co content in liver2.93.46.22.01.51.91.51.2-1.71.62.22.01.81.7-1.72.22.5
Cu content in liver3.13.86.81.32.11.21.22.6-2.62.21.92.61.31.8-1.21.92.4
Fe content in liver1.51.85.60.22.4-1.0-0.32.0-1.01.70.81.9-0.72.11.2-0.20.7
K content in liver0.10.10.40.00.3-0.20.0-0.20.40.5-0.10.0-0.40.30.4-0.70.0
Mg content in liver0.30.30.8-0.10.8-0.4-0.10.9-0.50.80.10.7-0.50.70.6-0.30.5
Mn content in liver0.60.72.2-0.51.2-0.7-0.31.5-0.81.20.11.1-0.90.90.9-0.40.3
Na content in liver0.80.92.7-0.90.5-1.2-1.20.6-0.2-0.1-0.70.3-1.50.51.6-1.4-0.3
Rb content in liver0.40.50.8-0.9-0.6-0.8-0.4-0.40.5-0.9-0.8-0.8-0.6-0.70.5-0.8-0.8
Se content in liver10.112.234.30.65.4-1.1-0.25.9-3.94.62.45.3-1.14.71.70.73.0
Sr content in liver2.12.04.01.50.41.91.6-0.1-1.20.51.70.71.70.8-1.92.01.6
Zn content in liver3.43.79.9-0.03.1-1.1-0.72.6-1.12.71.02.7-1.73.01.9-0.51.2