Hub : Genes

Xylt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000056658	0.14	0.06	4.2e-05	0.01	0.03	0.04	0.01	2.3e-02	5.5e-04	1.3e-05	8.2e-03
2	Brain	gene expression	ENSRNOG00000056658	0.12	0.07	9.7e-04	0.04	0.03	0.04	0.04	3.3e-04	4.8e-04	2.0e-04	1.6e-04
3	Brain	mRNA stability	ENSRNOG00000056658	0.05	0.03	2.6e-04	0.03	0.03	0.05	0.03	1.6e-03	6.5e-04	3.0e-05	1.5e-03
4	OFC	gene expression	ENSRNOG00000056658	0.23	0.14	1.5e-03	0.08	0.08	0.07	0.06	6.7e-03	7.3e-03	7.8e-03	1.3e-02
5	PL	gene expression	ENSRNOG00000056658	0.04	0.02	9.2e-04	0.05	0.04	0.04	0.04	1.9e-04	2.4e-04	3.3e-04	4.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	2.5	8.2	16.1	2.3	0.8	2.4	-3.6	-4.0
BMI without tail	5.9	12.4	27.4	1.9	0.8	3.5	-4.3	-5.2
Body weight	2.1	8.9	16.9	3.3	-0.4	1.7	-4.1	-3.7
Epididymis fat weight	1.1	2.6	5.5	2.2	0.5	0.5	-2.4	-1.5
Glucose	0.2	0.3	1.2	1.1	-0.0	0.2	-0.5	0.5
Heart weight	0.6	0.9	3.1	1.8	-1.0	0.1	-0.4	0.6
Left kidney weight	1.9	5.4	10.1	2.6	-1.2	0.5	-2.9	-3.2
Right kidney weight	2.3	6.6	13.6	3.1	-1.2	0.7	-2.9	-3.7
Tail length	1.5	4.5	7.7	1.8	-1.1	1.8	-2.7	-2.8
Length with tail	0.6	2.3	4.4	2.1	-1.4	0.0	-1.9	-1.1
Length without tail	0.8	1.8	3.4	1.0	-1.0	-1.8	0.6	1.7
Liver weight, left	0.5	0.9	1.2	0.7	1.0	0.7	-1.1	-1.0
Liver weight, right	1.3	2.2	3.4	0.3	1.8	1.6	-1.3	-1.7
Parametrial fat weight	2.7	5.2	9.5	2.6	-0.3	1.4	-3.1	-2.8
Retroperitoneal fat weight	1.4	4.5	13.7	3.7	0.6	0.2	-2.8	-0.7
Intraocular pressure	0.1	0.2	0.4	0.0	-0.2	0.6	-0.5	-0.4
Extensor digitorum longus weight	1.0	4.2	14.1	0.2	-1.5	2.0	-0.8	-3.8
Soleus weight	1.0	2.8	9.4	1.5	-3.1	-0.4	-0.7	-1.3
Tibialis anterior weight	2.0	6.9	15.1	1.9	-2.5	1.7	-2.6	-3.9
Tibia length	0.4	1.0	4.0	2.0	-0.9	-0.3	-0.4	0.2
Number of licking bursts	3.8	4.6	8.4	-1.6	-0.0	-2.2	2.7	2.9
Food consumed during 24 hour testing period	0.2	0.3	0.6	0.4	-0.8	-0.4	-0.2	-0.7
Times rat made contact with spout	0.4	0.4	0.7	-0.8	-0.8	-0.4	0.7	-0.3
Mean time between licks in bursts	0.2	0.3	1.2	-0.6	1.1	-0.2	-0.0	-0.1
Mean num. licks in bursts	2.6	3.2	7.9	1.0	-0.7	1.6	-2.0	-2.8
Std. dev. time between licks in bursts	0.6	0.7	2.4	-0.1	1.6	0.4	-0.6	-0.8
Water consumed over 24 hours	2.1	2.5	5.7	-2.1	-0.1	-1.2	2.4	1.0
Indifference point 0 sec	1.4	2.2	5.5	2.3	-0.4	0.8	-2.1	-0.8
Indifference point AUC	0.3	0.3	0.9	0.4	-0.9	-0.4	-0.6	-0.4
Indifference point function ln k	0.1	0.2	0.3	0.5	-0.2	0.4	-0.5	-0.4
Indifference point function log k	0.1	0.2	0.3	0.5	-0.2	0.4	-0.5	-0.4
Delay discounting total patch changes 0 sec	1.7	2.7	6.1	2.5	-0.3	0.9	-2.4	-1.0
Delay discounting total patch changes 12 sec	0.3	0.4	1.0	0.4	0.2	0.9	-1.0	-0.5
Delay discounting total patch changes 18 sec	0.1	0.1	0.3	0.0	-0.6	-0.2	-0.3	0.1
Delay discounting total patch changes 24 sec	1.2	1.6	3.6	1.9	-0.9	0.5	-1.6	-0.7
Delay discounting total patch changes 6 sec	1.1	1.7	4.2	2.0	-1.4	-0.5	-1.1	1.0
Delay discounting time to switch 0 sec	2.3	3.5	7.5	-2.7	1.6	-0.6	2.2	1.5
Delay discounting water rate 0 sec	0.5	0.8	1.9	1.3	-0.1	0.4	-1.4	-0.8
Delay discounting water rate 12 sec	2.7	4.0	8.1	2.5	-0.9	1.2	-2.8	-1.9
Delay discounting water rate 18 sec	0.9	1.2	2.5	1.5	0.1	1.0	-1.6	-0.5
Delay discounting water rate 24 sec	0.5	0.7	1.8	1.3	-1.2	-0.0	-0.4	-0.2
Delay discounting water rate 6 sec	0.9	1.2	3.9	2.0	-1.2	0.2	-0.9	0.1
Locomotor activity	1.0	1.5	3.1	-0.1	0.9	1.4	-1.8	-1.3
Locomotor testing distance	0.7	1.2	3.3	0.5	0.2	1.0	-1.8	-1.1
Locomotor testing rearing	1.0	1.6	3.3	1.1	1.1	1.3	-1.8	-0.8
Light reinforcement 1	0.2	0.4	1.0	-0.3	1.0	0.3	-0.0	0.9
Light reinforcement 2	0.1	0.1	0.2	0.4	0.1	-0.3	-0.3	0.4
Reaction time number correct	0.9	1.2	2.3	-1.3	1.5	1.4	-0.5	0.3
Reaction time mean minus median	0.2	0.2	0.3	0.5	-0.3	-0.4	-0.2	-0.6
Reaction time mean minus median AUC	0.1	0.2	0.5	0.7	0.1	-0.1	-0.5	-0.3
Reaction time num false alarms	1.3	1.8	3.8	-0.5	-1.2	-0.7	2.0	1.8
Reaction time num false alarms AUC	0.9	1.3	2.8	-1.0	-0.6	-0.4	1.7	1.5
Reaction time trials correct on left	0.9	1.2	2.3	-1.3	1.5	1.4	-0.5	0.3
Reaction time trials on left	0.9	1.3	2.5	-1.3	1.6	1.4	-0.5	0.2
Reaction time mean	0.3	0.5	1.1	0.6	-0.3	0.4	-0.8	-1.1
Reaction time mean AUC	0.2	0.3	0.7	0.3	0.0	0.4	-0.6	-0.9
Median of all reaction times	0.3	0.5	1.2	0.3	-0.1	0.7	-0.8	-1.1
Reaction time omissions	0.8	1.1	2.7	-1.1	1.7	0.6	-0.7	-0.7
Reaction time false alarm rate	1.3	1.9	3.9	-0.5	-1.5	-1.3	2.0	1.2
Reaction time premature initiation rate	0.3	0.4	1.1	-0.5	-0.7	-0.1	0.4	-1.0
Reaction time premature initiations	0.3	0.5	1.7	-1.3	0.2	0.5	0.4	-0.6
Std. dev. reaction times	0.4	0.5	1.0	1.0	-0.3	0.1	-0.9	-0.9
Reaction time trials completed	0.9	1.3	2.5	-1.3	1.6	1.4	-0.5	0.2
Reaction time trials AUC	0.8	1.1	2.0	-1.2	1.4	1.4	-0.6	0.1
Social response proportion	0.9	1.0	1.5	1.0	1.0	1.1	-1.2	-0.6
Social responses	0.7	0.9	2.8	-0.5	1.7	1.1	-0.4	0.4
Social time	0.3	0.4	1.2	-0.7	0.4	0.1	0.2	1.1
Conditioned locomotion	0.7	0.9	2.8	-1.7	1.0	0.3	0.6	0.1
Cocaine response after cond. corrected	0.1	0.1	0.2	-0.3	-0.4	-0.4	0.4	0.3
Cocaine response after cond. not corrected	0.2	0.2	1.0	-0.2	-0.4	0.1	-0.3	-1.0
Cocaine response before conditioning	1.2	1.5	5.7	0.1	-0.1	0.8	-1.1	-2.4
Saline control response	0.4	0.5	1.5	1.2	0.4	0.5	-0.8	-0.4
Condit. Reinf. active minus inactive responses	1.4	1.8	4.9	2.2	0.5	0.1	-1.8	-0.6
Condit. Reinf. active-inactive response ratio	1.2	1.2	3.7	1.9	0.7	-0.2	-1.3	-0.4
Condit. Reinf. active responses	0.7	0.9	1.9	1.4	0.6	0.2	-1.4	-0.7
Condit. Reinf. inactive responses	0.2	0.3	0.6	-0.2	-0.0	0.7	-0.3	-0.8
Condit. Reinf. lever presses	1.9	2.6	5.5	1.3	0.6	0.9	-2.3	-2.1
Condit. Reinf. lever reinforcers received	0.6	0.9	1.9	1.2	0.8	0.2	-1.4	-0.5
Pavlov. Cond. lever latency	2.0	2.8	5.8	-1.9	-0.2	-0.9	2.4	1.9
Pavlov. Cond. magazine entry latency	0.5	0.6	1.5	-0.7	1.2	-0.2	1.0	0.1
Pavlov. Cond. change in total contacts	1.8	2.5	8.0	2.8	-0.0	0.3	-2.1	-0.2
Pavlov. Cond. index score	0.5	0.7	1.1	1.1	0.7	0.3	-1.0	-0.8
Pavlov. Cond. latency score	0.4	0.5	0.8	0.8	0.6	0.4	-0.8	-0.9
Pavlov. Cond. lever contacts	2.7	3.8	7.7	2.1	0.6	1.2	-2.8	-2.3
Pavlov. Cond. magazine entry number	0.4	0.5	0.8	-0.2	-0.9	0.5	-0.7	-0.8
Pavlov. Cond. intertrial magazine entries	1.7	2.2	4.9	0.7	0.4	1.3	-2.0	-2.2
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.0	1.0	0.8	0.3	-0.9	-0.8
Pavlov. Cond. response bias	1.1	1.6	2.7	1.6	0.9	0.4	-1.6	-1.3
Conditioned reinforcement - actives	1.7	1.7	5.8	0.5	-2.4	-1.6	0.1	0.1
Conditioned reinforcement - inactives	2.2	2.5	6.7	-0.0	-1.9	-2.6	1.0	1.1
Conditioned locomotion	0.6	0.7	1.5	-1.2	-0.6	-0.5	0.8	0.8
Intermittent access intake day 1-15 change	2.8	2.7	5.1	-1.5	-0.9	-2.3	2.0	1.2
Intermittent access intake escalation	2.4	2.4	5.2	-1.0	-1.0	-2.3	1.9	1.2
Intermittent access intake escalation 2	2.7	2.6	4.8	-1.2	-0.8	-2.2	2.1	1.3
Intermitt. access day 1 inactive lever presses	1.3	1.4	3.5	0.3	-1.5	-1.9	0.8	0.6
Intermitt. access day 15 inactive lever presses	0.4	0.4	0.8	-0.6	-0.8	-0.9	0.3	-0.3
Intermitt. access escalation Index	0.3	0.2	0.8	0.6	0.2	-0.1	-0.3	-0.9
Intermittent access day 1 total infusions	1.1	1.2	3.2	1.2	-0.0	0.2	-1.8	-1.1
Intermittent access day 15 total infusions	0.5	0.5	2.0	0.4	-0.7	-1.4	-0.1	0.1
Intermittent access terminal intake (last 3 days)	0.4	0.5	1.6	0.5	-0.6	-1.3	-0.2	0.1
Intermittent access total infusions	0.7	0.8	1.5	1.2	-0.6	-0.7	-1.1	-0.7
Intermittent access day 1 locomotion	1.0	1.0	2.6	1.4	-0.1	0.2	-1.6	-0.6
Intermittent access day 15 total locomotion	0.7	0.8	2.0	1.4	-0.7	-0.7	-0.6	0.6
Intermittent access total locomotion	0.8	0.9	2.3	1.5	0.2	0.1	-1.5	-0.2
Intermittent access standard deviation	0.8	0.8	2.1	0.4	-1.3	-1.5	0.3	0.2
Cocaine induced anxiety	0.2	0.2	0.5	0.5	0.7	-0.6	-0.1	0.0
Post-drug Anxiety	0.7	0.8	2.1	1.5	-0.7	-0.9	0.0	0.7
Baseline Anxiety	1.4	1.5	5.2	0.2	-2.3	-1.1	0.9	0.7
Lifetime Intake	1.2	1.4	2.7	1.4	-0.6	-0.4	-1.7	-1.3
Incentive Sensitization - Responses	0.9	0.9	1.7	-1.1	1.0	1.3	-0.5	-0.6
Incentive Sensitization - Breakpoint	0.9	0.9	1.8	-1.0	0.9	1.3	-0.6	-0.6
Progressive ratio test 1 active lever presses	0.4	0.5	1.1	0.5	0.4	-0.7	-1.0	-0.5
Progressive ratio test 1 breakpoint	0.5	0.5	1.2	0.6	0.4	-0.7	-1.1	-0.6
Progressive ratio test 1 inactive lever presses	0.7	0.7	1.8	0.3	0.1	-0.2	-1.3	-1.3
Progressive ratio test 2 active lever presses	0.3	0.4	1.1	0.5	0.1	0.0	-1.1	-0.7
Progressive ratio test 2 breakpoint	0.4	0.4	1.5	0.3	0.2	0.2	-1.2	-0.7
Progressive ratio test 2 inactive lever presses	0.2	0.2	0.6	0.4	0.2	-0.3	-0.8	-0.2
Total sessions with >9 infusions	2.1	2.3	4.6	1.1	-1.5	-0.4	-1.7	-2.1
Short access day 1 total inactive lever presses	0.4	0.4	0.7	0.8	-0.9	-0.5	-0.7	-0.1
Short access day 10 total inactive lever presses	1.4	1.6	4.5	0.4	-1.4	-2.1	0.9	0.7
Short access day 1 total infusions	2.0	2.1	3.5	1.6	-1.3	-0.6	-1.9	-1.5
Short access day 10 total infusions	0.8	0.9	2.1	0.5	-0.6	-0.5	-1.3	-1.5
Short access total infusions	2.4	2.6	5.4	1.7	-0.9	-0.1	-2.3	-2.0
Short access day 1 locomotion	0.6	0.6	1.6	0.6	-1.3	-0.1	-0.8	-0.6
Short access day 10 total locomotion	1.4	1.5	2.7	0.3	0.8	1.5	-1.6	-1.4
Short access total locomotion	2.4	2.4	5.5	2.2	-0.6	0.6	-2.3	-1.1
Compulsive drug intake	2.4	2.4	6.1	0.1	1.8	2.5	-1.3	-1.1
One hour access (0.3 mA shock)	0.4	0.5	1.2	0.2	0.5	0.2	-1.1	-1.0
One hour access (shock baseline)	1.1	1.3	4.5	0.1	-1.0	-2.1	0.6	0.9
Number of responses in last shaping day	0.4	0.4	0.7	0.8	-0.4	-0.7	-0.6	-0.3
Context. condit. distance diff. score	0.2	0.3	0.6	-0.5	0.8	0.1	0.0	0.7
Locomotion velocity, session 1	0.9	1.0	1.5	-0.7	-1.0	-1.0	1.2	1.0
Locomotion distance, session 1	0.3	0.4	0.8	0.7	-0.0	0.7	-0.9	-0.5
Locomotion velocity, session 2	1.1	1.3	2.1	-0.6	-0.9	-1.1	1.4	1.5
Locomotion distance, session 2	0.2	0.4	0.7	0.5	-0.8	0.4	-0.5	-0.7
Locomotion velocity, session 3	0.1	0.1	0.2	-0.4	0.2	0.3	0.0	-0.1
Locomotion distance, session 3	0.5	0.6	1.9	-1.4	0.5	-0.1	0.8	-0.3
Stereotopy head waving bouts, day 3	0.2	0.3	1.1	0.5	0.0	-0.4	-0.1	1.0
Stereotopy head waving duration, day 3	0.3	0.3	1.0	0.7	-0.2	-0.2	-0.1	1.0
Locomotion velocity, session 7	0.6	0.6	1.8	-1.4	0.7	0.7	0.2	-0.6
Locomotion distance, session 7	0.3	0.3	0.8	-0.9	-0.2	-0.0	0.9	0.4
Stereotopy head waving bouts, day 7	0.1	0.1	0.3	0.4	-0.2	0.3	-0.6	0.1
Stereotopy head waving duration, day 7	0.8	0.9	1.7	0.6	0.3	1.0	-1.3	-1.2
Locomotion velocity, session 8	0.5	0.6	1.0	-1.0	-0.5	-0.7	0.7	1.0
Locomotion distance, session 8	0.1	0.1	0.4	0.2	-0.2	0.1	-0.1	0.6
Degree of sensitization distance	0.9	0.9	2.5	1.6	-1.0	-0.1	-0.6	0.8
Degree of sensitization stereotypy	0.3	0.3	0.5	0.2	-0.2	0.7	-0.6	-0.7
Condit. Reinf. active minus inactive responses	0.2	0.3	0.6	-0.5	0.5	0.3	-0.8	-0.1
Condit. Reinf. active-inactive response ratio	0.9	0.9	1.7	-0.4	0.9	1.1	-1.3	-0.9
Condit. Reinf. active responses	0.1	0.2	0.3	0.5	0.2	-0.4	-0.3	0.5
Condit. Reinf. inactive responses	0.8	1.0	2.8	1.7	-0.3	-1.1	0.4	0.8
Incentive salience index mean	0.4	0.5	1.5	-1.2	0.8	0.5	-0.2	-0.4
Condit. Reinf. lever presses	0.6	0.8	2.1	-1.4	1.1	0.2	0.8	-0.1
Time in familiar zone, hab. session 1	0.3	0.2	0.4	0.7	-0.6	-0.2	0.1	0.6
Time in novel zone, hab. session 1	0.4	0.4	0.6	-0.4	0.7	0.7	-0.6	-0.8
Total zone transitions, hab. session 1	0.8	1.1	2.2	1.5	-1.4	0.1	-1.0	-0.4
Total locomotion distance, hab. session 1	2.5	3.6	7.5	2.7	-2.0	0.7	-2.1	-1.2
Locomotion velocity, hab. session 1	2.0	2.9	6.1	2.5	-1.4	0.8	-2.1	-1.2
Time in familiar zone, hab. session 2	0.7	0.7	1.8	1.3	-0.4	0.5	-0.8	-0.8
Time in novel zone, hab. session 2	0.1	0.1	0.1	-0.4	0.4	-0.3	0.1	0.0
Total zone transitions, hab. session 2	0.9	1.2	2.9	1.7	-0.7	0.5	-1.4	-0.5
Total locomotion distance, hab. session 2	1.2	1.6	3.5	1.9	-1.7	0.3	-1.2	-0.4
Locomotion velocity, hab. session 2	1.1	1.4	2.9	1.7	-1.5	0.4	-1.2	-0.5
Novel to familiar place preference ratio	0.9	0.9	1.7	0.8	-0.8	-1.3	0.5	1.2
Novelty place preference	1.4	1.4	2.7	0.6	-1.1	-1.6	0.9	1.4
Time in novel zone, NPP test	1.2	1.2	2.2	1.0	-1.0	-1.5	0.5	1.3
Total zone transitions, NPP test	0.3	0.4	0.6	0.6	-0.8	0.4	-0.7	-0.7
Total locomotion distance, NPP test	0.8	1.1	3.0	1.5	-1.7	-0.3	-0.3	-0.2
Locomotion velocity, NPP test	0.6	0.9	2.8	1.1	-1.7	-0.4	-0.1	-0.1
Pavlov. Cond. lever latency	2.6	3.2	5.5	2.3	-2.3	-1.6	0.1	1.7
Pavlov. Cond. magazine entry latency	3.5	4.5	8.7	-1.0	2.5	2.2	-1.4	-3.0
Pavlov. Cond. change in total contacts	2.6	2.8	5.1	-2.3	2.0	1.1	0.5	-1.8
Pavlov. Cond. index score	3.8	4.8	8.7	-1.9	3.0	2.2	-0.6	-2.5
Pavlov. Cond. latency score	3.2	4.1	7.1	-1.8	2.7	2.1	-0.6	-2.3
Pavlov. Cond. lever contacts	3.4	4.0	7.0	-2.1	2.6	1.9	-0.2	-2.2
Pavlov. Cond. magazine entry number	3.2	4.0	6.4	1.9	-2.5	-2.0	0.5	2.4
Pavlov. Cond. intertrial magazine entries	1.4	1.7	2.6	1.6	-1.2	-1.4	-0.0	1.6
Pavlov. Cond. lever-magazine prob. diff.	4.3	5.5	9.6	-1.9	3.1	2.3	-0.8	-2.8
Pavlov. Cond. response bias	3.6	4.5	7.8	-2.5	2.8	1.8	0.0	-2.2
Bone: apparent density	0.5	0.9	1.8	1.4	-1.0	0.4	-1.1	-0.5
Bone surface	0.4	0.6	1.3	0.8	-0.5	0.4	-0.9	-1.1
Bone volume	0.6	1.0	1.6	1.3	-1.0	0.4	-1.1	-1.0
Bone: connectivity density	0.5	0.7	1.5	0.8	0.1	0.7	-1.0	-1.2
Bone: cortical apparent density	0.8	1.1	2.9	-0.8	-0.3	-0.4	1.7	1.3
Bone: cortical area	1.2	1.9	3.1	1.8	-1.2	0.3	-1.6	-1.5
Bone: cortical porosity	0.7	0.8	1.6	0.1	0.7	0.7	-1.3	-1.2
Bone: cortical porosity	0.6	0.6	1.3	0.0	0.9	0.6	-1.1	-0.7
Bone: cortical thickness	0.9	1.5	4.1	1.6	-2.0	-0.4	-0.7	-0.3
Bone: cortical thickness	1.7	2.0	6.0	1.7	-2.5	-0.9	0.0	0.4
Bone: cortical tissue density	0.8	1.0	2.8	-0.8	-0.3	-0.4	1.7	1.3
Bone: elastic displacement	0.7	0.8	2.5	-0.7	-0.6	-0.6	0.6	1.6
Bone: elastic work	0.1	0.1	0.4	0.1	-0.6	-0.0	-0.3	0.0
Bone: endosteal estimation	0.8	1.8	5.5	-0.1	0.5	1.1	-1.4	-2.4
Bone: endosteal perimeter	0.2	0.4	1.8	-0.1	0.3	0.1	-0.3	-1.4
Bone: final force	1.1	1.9	3.6	1.1	-1.1	1.0	-1.5	-1.9
Bone: final moment	1.0	1.6	2.8	1.0	-0.9	1.0	-1.6	-1.7
Bone: marrow area	0.8	1.7	5.2	-0.1	0.5	1.1	-1.4	-2.3
Bone: maximum diameter	0.8	1.4	3.4	1.1	-0.1	0.6	-1.5	-1.8
Bone: maximum force	1.1	1.8	3.5	1.1	-1.1	0.9	-1.5	-1.9
Bone: maximum moment	0.9	1.6	2.8	1.1	-1.0	0.9	-1.6	-1.7
Bone: minimum diameter	0.4	0.8	2.2	0.7	-0.1	0.6	-1.0	-1.5
Bone: periosteal estimation	1.1	2.2	5.7	1.2	-0.4	0.8	-1.8	-2.4
Bone: periosteal perimeter	0.9	1.5	2.6	1.3	0.4	0.6	-1.5	-1.6
Bone: post-yield work	3.6	4.9	7.8	0.9	1.8	2.2	-2.8	-2.8
Bone: stiffness	1.1	1.7	3.7	1.5	-1.9	0.1	-0.9	-1.2
Bone: tissue strength	0.3	0.3	0.9	-1.0	-0.3	-0.1	0.6	0.3
Bone: trabecular number	0.3	0.5	1.5	1.2	-1.0	0.2	-0.4	0.1
Bone: trabecular spacing	1.4	1.8	4.3	-1.7	2.1	1.1	-0.1	-0.7
Bone: trabecular thickness	2.7	3.3	8.8	3.0	-2.2	-0.3	-1.7	-0.1
Bone: trabecular tissue density	0.6	0.8	1.2	-0.2	-1.1	-1.1	0.7	1.0
Breakpoint value in progressive ratio session	1.5	1.7	4.5	-0.8	0.6	-1.0	1.4	2.1
Distance traveled before self-admin	1.0	1.0	2.4	0.4	-1.5	-1.0	1.1	0.7
Distance traveled after self-admin	0.7	0.8	2.4	-0.3	-1.5	-0.9	0.7	-0.5
Delta time in closed arm before/after self-admin	1.1	1.0	3.0	-1.7	1.3	0.3	0.6	-0.2
Delta time in open arm before/after self-admin	2.7	2.6	5.2	2.3	-1.0	0.6	-2.0	-1.5
Diff in mean of infusions in LGA sessions	0.9	1.0	2.0	1.1	-0.1	-1.4	0.1	1.4
Extinction: sum of active levers before priming	1.2	1.3	2.1	-1.4	0.0	-1.1	1.4	1.0
Active lever presses in extinction session 6	0.2	0.2	0.6	0.4	0.3	-0.8	-0.1	0.4
Delta distance traveled before/after self-admin	0.6	0.6	1.9	-0.5	0.3	0.2	-0.9	-1.4
Delta ambulatory time before/after self-admin	0.4	0.5	1.3	-0.5	-0.1	0.5	-0.7	-1.1
Time in closed arm before self-admin	0.8	0.9	1.4	1.2	-0.8	0.8	-1.2	-0.8
Time in closed arm after self-admin	0.4	0.4	1.3	0.7	-0.5	-0.1	0.3	1.1
Time in open arm before self-admin	1.9	2.0	3.5	-1.2	1.1	-1.1	1.9	1.6
Time in open arm after self-admin	0.4	0.4	1.6	0.2	-0.3	-0.5	-0.3	-1.3
Sum of active levers in priming session hrs 5-6	0.4	0.4	1.9	-0.2	1.4	-0.3	-0.2	-0.1
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.1	0.4	-0.0	0.0	0.2	-0.3
Time to tail flick, vehicle, after self-admin	0.7	0.8	2.5	-0.5	1.6	0.1	0.2	1.1
Time to tail flick, test, before self-admin	0.3	0.3	0.6	-0.6	-0.4	-0.7	0.8	-0.2
Time to tail flick, test, after self-admin	1.0	1.0	2.0	-1.4	1.4	-0.1	1.1	0.1
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.7	-0.1	1.3	0.8	-0.9	-0.1
Delta time to tail flick, test, before/after SA	0.4	0.4	1.5	-0.4	1.2	0.2	-0.3	-0.4
Ambulatory time before self-admin	2.1	2.2	3.9	0.5	-2.0	-1.8	1.4	1.3
Ambulatory time after self-admin	1.1	1.3	3.6	-0.4	-1.9	-1.3	0.9	-0.3
Total heroin consumption	0.7	0.9	2.3	-0.6	1.2	-0.3	0.2	1.5
Area under the delay curve	0.4	0.4	0.9	0.7	-0.9	-0.4	0.3	0.7
Delay disc. indifference point, 0s delay	0.7	0.7	2.6	-0.0	-1.6	-0.8	0.6	-0.1
Delay disc. indifference point, 16s delay	2.3	2.3	8.5	0.3	-0.3	-0.9	1.4	2.9
Delay disc. indifference point, 2s delay	1.0	1.1	2.6	0.6	-1.3	0.4	-0.8	-1.6
Delay disc. indifference point, 24s delay	1.4	1.4	3.2	-0.6	0.0	-0.6	1.7	1.8
Delay disc. indifference point, 4s delay	1.6	1.7	4.2	1.7	-2.0	-0.7	0.2	0.8
Delay disc. indifference point, 8s delay	0.3	0.4	1.2	-0.3	-1.1	-0.3	0.5	0.4
Delay discount exponential model param	0.3	0.3	0.5	-0.7	0.7	0.2	-0.2	-0.6
Delay discount hyperbolic model param	0.3	0.3	0.9	-0.8	0.9	0.2	-0.1	-0.4
Fecal boli incidents, locomotor time 1	1.9	2.1	4.9	-1.1	2.2	2.1	-0.0	0.1
Change in fecal boli incidents, locomotor task	3.6	3.4	6.5	2.5	-2.2	-2.2	-0.5	1.0
Time >=10cm from walls, locomotor time 1	0.3	0.3	0.7	-0.5	-0.8	-0.6	0.4	0.2
Bouts of movement, locomotor time 1	1.3	1.5	2.0	-0.3	1.3	-1.4	1.4	1.3
Total resting periods, locomotor time 1	1.9	2.1	3.1	-0.8	1.4	-1.3	1.8	1.7
Rest time, locomotor task time 1	2.5	2.7	5.4	-1.3	-0.3	-1.6	2.3	2.0
Distance moved, locomotor task time 1	1.8	1.9	5.0	1.1	-0.3	0.8	-2.2	-1.7
Vertical activity count, locomotor time 1	1.1	1.2	3.5	0.6	-1.9	0.1	-0.8	-1.2
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.4	-0.1	-1.2	0.1	0.1	-0.8
Bouts of movement, locomotor time 2	2.8	3.0	7.3	-1.1	2.7	1.9	-0.8	-1.5
Total resting periods, locomotor time 2	2.5	2.7	6.1	-0.9	2.5	1.7	-0.9	-1.6
Rest time, locomotor task time 2	0.4	0.5	0.9	0.6	-0.6	-0.9	0.3	0.9
Distance moved, locomotor task time 2	0.6	0.7	1.3	-1.1	-1.1	-0.6	0.8	-0.1
Vertical activity count, locomotor time 2	1.3	1.4	4.8	-0.5	-2.2	-1.0	0.9	0.2
Weight adjusted by age	1.3	1.5	4.4	-0.2	2.1	1.1	-1.1	-0.6
Seeking ratio, delayed vs. immediate footshock	0.0	0.1	0.2	0.1	-0.1	-0.1	0.5	0.2
Locomotion in novel chamber	1.8	2.2	4.4	2.1	0.8	0.4	-1.8	-1.7
Locomotion in novel chamber post-restriction	1.0	1.2	3.0	1.7	0.5	-0.2	-1.6	-0.1
Progressive ratio	0.5	0.6	1.4	1.2	-0.5	-1.0	-0.2	0.4
Food seeking constrained by brief footshock	0.9	1.1	2.5	-0.0	-0.6	-1.6	1.0	1.3
Seeking ratio, punishment vs. effort	0.4	0.5	1.2	-1.1	0.6	0.9	0.1	-0.5
Run reversals in cocaine runway, females	1.8	1.8	4.4	0.4	-1.9	-0.6	-0.6	-2.1
Run reversals in cocaine runway, males	0.7	0.7	1.1	-0.7	-0.5	-0.9	1.0	0.8
Latency to leave start box in cocaine runway	0.5	0.5	1.4	1.2	-0.3	0.3	-0.7	0.8
Latency to leave start box in cocaine runway, F	0.4	0.5	1.3	0.2	1.2	0.7	-0.6	0.2
Latency to leave start box in cocaine runway, M	1.2	1.1	2.5	1.0	-1.6	-0.5	0.2	1.4
Cd content in liver	0.4	0.4	1.0	0.3	0.8	-0.4	0.3	1.0
Co content in liver	1.6	1.8	2.6	1.4	-1.6	-1.6	0.3	1.4
Cu content in liver	0.9	1.1	3.8	2.0	-0.7	-0.2	-1.1	-0.4
Fe content in liver	2.4	2.8	3.9	1.1	-1.8	-1.9	1.4	2.0
K content in liver	0.2	0.2	0.6	-0.2	0.8	0.6	-0.1	-0.3
Mg content in liver	1.1	1.1	3.7	-0.5	1.9	1.1	-0.6	-0.4
Mn content in liver	0.6	0.7	1.3	-0.8	0.6	1.1	0.3	-0.9
Na content in liver	1.3	1.4	3.8	-1.2	0.6	1.3	-0.2	-1.9
Rb content in liver	0.7	0.9	2.4	1.5	0.5	-0.3	-1.0	0.9
Se content in liver	0.1	0.2	0.5	0.7	-0.1	-0.1	0.4	-0.3
Sr content in liver	1.3	1.2	2.6	-0.4	1.1	1.3	-0.6	-1.6
Zn content in liver	2.0	2.2	5.6	0.4	0.4	1.6	-1.6	-2.4