Hub : Genes

Gls

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000078073 0.43 0.14 7.4e-07 0.01 0.05 0.04 0.01 3.4e-02 1.5e-06 3.5e-05 2.2e-02
2 Adipose alternative polyA ENSRNOT00000090026 0.45 0.13 3.2e-07 0 0.05 0.04 0.01 7.9e-02 1.1e-06 3.0e-05 3.8e-02
3 Adipose gene expression ENSRNOG00000056246 0.3 0.13 4.8e-04 -0 0.01 0.02 0 4.5e-01 6.7e-02 4.6e-03 3.7e-01
4 Adipose isoform ratio ENSRNOT00000078073 0.38 0.14 2.9e-05 0 0.03 0.02 0 1.7e-01 1.2e-04 2.0e-03 1.4e-01
5 Adipose mRNA stability ENSRNOG00000056246 0.04 0.03 3.4e-05 0.02 0.01 0.01 0.01 2.1e-03 6.8e-03 1.1e-02 9.9e-03
6 Brain alternative polyA ENSRNOT00000078073 0.03 0.03 9.1e-03 0.01 0.02 0.01 0.01 5.6e-02 7.3e-03 5.1e-02 2.5e-02
7 Brain alternative polyA ENSRNOT00000090026 0.03 0.03 2.7e-03 0.02 0.03 0.02 0.03 2.6e-03 2.1e-03 4.9e-03 1.8e-03
8 Brain isoform ratio ENSRNOT00000078073 0.03 0.03 5.6e-03 0.01 0.02 0.01 0.01 1.6e-02 3.7e-03 3.9e-02 1.7e-02
9 Brain isoform ratio ENSRNOT00000090026 0.03 0.03 1.0e-03 0.02 0.02 0.01 0.01 4.0e-03 5.4e-03 6.2e-02 2.4e-02
10 NAcc alternative polyA ENSRNOT00000078073 0.04 0.03 4.4e-03 0.03 0.02 0.02 0.02 2.5e-03 6.2e-03 1.2e-02 6.4e-03
11 NAcc alternative polyA ENSRNOT00000090026 0.03 0.03 8.7e-03 0.02 0.02 0.01 0.01 1.5e-02 1.6e-02 7.0e-02 4.5e-02
12 NAcc gene expression ENSRNOG00000056246 0.2 0.19 4.2e-04 0 0.04 0.03 0.02 1.3e-01 9.1e-04 4.9e-03 9.6e-03
13 PL gene expression ENSRNOG00000056246 0.04 0.05 7.9e-03 0 0.01 -0 0 1.2e-01 3.0e-02 7.8e-01 3.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail6.019.422.14.4-4.43.54.33.84.6-4.74.6-4.54.5-4.5-4.6-4.5
BMI without tail1.32.73.51.4-1.31.31.31.61.8-1.91.9-1.71.7-1.7-1.8-1.8
Body weight0.00.20.60.5-0.7-0.30.8-0.60.3-0.30.2-0.20.3-0.3-0.6-0.1
Epididymis fat weight0.30.81.4-0.80.7-1.2-0.5-1.2-0.91.0-0.90.9-0.80.80.51.0
Glucose0.50.81.21.1-1.10.60.90.51.0-1.01.0-1.00.8-0.8-0.8-1.0
Heart weight0.60.91.4-0.90.9-0.9-1.0-1.2-0.90.8-0.90.8-1.01.00.90.9
Left kidney weight0.00.10.5-0.1-0.0-0.70.2-0.5-0.30.2-0.30.3-0.20.20.10.4
Right kidney weight0.10.20.90.5-0.6-0.30.90.30.4-0.40.3-0.40.4-0.4-0.7-0.2
Tail length4.613.815.1-3.93.8-3.5-3.5-3.6-3.83.9-3.83.8-3.83.83.43.8
Length with tail4.315.718.5-3.83.5-3.7-3.3-4.2-4.24.3-4.24.1-4.14.03.64.3
Length without tail0.30.61.5-0.2-0.1-1.00.2-1.2-0.80.8-0.90.7-0.70.70.41.0
Liver weight, left0.00.10.1-0.30.3-0.4-0.2-0.3-0.30.3-0.30.3-0.20.20.20.3
Liver weight, right0.00.00.1-0.30.20.2-0.1-0.2-0.10.4-0.20.20.1-0.1-0.10.2
Parametrial fat weight0.00.00.30.1-0.2-0.50.3-0.20.1-0.20.1-0.0-0.00.0-0.2-0.0
Retroperitoneal fat weight0.10.20.60.5-0.70.10.8-0.40.4-0.30.3-0.30.4-0.4-0.7-0.2
Intraocular pressure0.30.50.80.8-0.70.30.80.90.6-0.70.7-0.70.7-0.7-0.6-0.6
Extensor digitorum longus weight4.016.226.04.4-4.72.45.13.74.0-4.03.9-4.03.7-3.8-4.5-3.5
Soleus weight0.30.81.61.0-1.20.81.30.90.7-0.70.7-0.70.8-0.9-1.0-0.6
Tibialis anterior weight2.69.111.63.3-3.32.33.42.53.1-3.23.0-3.12.8-2.8-3.2-2.9
Tibia length4.613.114.4-3.63.5-3.5-3.3-3.8-3.73.8-3.73.7-3.63.63.43.7
Number of licking bursts0.20.20.40.4-0.40.50.1-0.10.5-0.50.5-0.50.5-0.5-0.3-0.6
Food consumed during 24 hour testing period0.70.81.1-0.80.8-1.1-0.8-1.0-0.90.8-0.90.8-1.01.00.90.9
Times rat made contact with spout0.10.10.3-0.20.4-0.5-0.5-0.00.1-0.20.1-0.2-0.30.30.3-0.1
Mean time between licks in bursts1.42.02.41.5-1.51.31.61.51.4-1.41.3-1.31.4-1.4-1.4-1.3
Mean num. licks in bursts0.10.10.5-0.30.4-0.7-0.10.3-0.20.1-0.20.1-0.40.40.20.3
Std. dev. time between licks in bursts6.88.19.23.0-3.02.92.92.42.8-2.82.8-2.82.9-2.9-2.8-2.8
Water consumed over 24 hours0.50.61.00.7-0.60.10.60.40.9-1.00.9-1.00.7-0.7-0.8-0.9
Indifference point 0 sec4.16.68.62.6-2.42.52.22.92.6-2.82.7-2.62.6-2.6-2.2-2.7
Indifference point AUC0.40.51.80.5-0.51.30.31.00.6-0.60.6-0.60.7-0.7-0.4-0.7
Indifference point function ln k0.81.11.41.1-1.01.00.90.91.1-1.11.2-1.11.1-1.1-1.0-1.2
Indifference point function log k0.81.11.41.1-1.01.00.90.91.1-1.11.2-1.11.1-1.1-1.0-1.2
Delay discounting total patch changes 0 sec4.16.69.12.5-2.32.62.13.02.6-2.72.7-2.62.6-2.6-2.1-2.8
Delay discounting total patch changes 12 sec0.70.91.90.9-0.81.10.71.40.9-1.00.9-0.91.0-1.0-0.7-1.0
Delay discounting total patch changes 18 sec2.22.96.31.6-1.41.81.32.51.7-1.81.7-1.71.7-1.7-1.3-1.8
Delay discounting total patch changes 24 sec1.21.54.21.2-1.00.91.02.01.2-1.41.2-1.31.0-1.0-0.8-1.3
Delay discounting total patch changes 6 sec4.06.08.82.3-2.23.01.92.92.4-2.52.5-2.42.5-2.5-2.0-2.6
Delay discounting time to switch 0 sec1.01.61.9-1.21.1-1.4-1.0-1.3-1.31.3-1.31.3-1.31.31.21.3
Delay discounting water rate 0 sec0.81.31.81.1-1.01.01.11.31.2-1.21.2-1.21.1-1.1-1.2-1.2
Delay discounting water rate 12 sec0.30.40.70.5-0.40.30.40.80.7-0.80.7-0.70.5-0.5-0.6-0.7
Delay discounting water rate 18 sec0.00.00.20.1-0.1-0.20.0-0.50.2-0.20.2-0.30.1-0.1-0.1-0.2
Delay discounting water rate 24 sec0.10.10.6-0.20.1-0.80.1-0.4-0.10.2-0.20.1-0.30.3-0.10.3
Delay discounting water rate 6 sec1.01.42.11.2-1.10.90.90.91.4-1.41.4-1.31.1-1.1-1.1-1.4
Locomotor activity0.00.10.10.3-0.2-0.20.2-0.10.2-0.30.2-0.30.2-0.2-0.2-0.3
Locomotor testing distance0.00.00.2-0.10.3-0.0-0.5-0.1-0.0-0.10.00.0-0.00.00.3-0.1
Locomotor testing rearing0.40.70.90.8-0.80.70.60.40.9-0.90.9-0.90.8-0.8-0.7-0.9
Light reinforcement 13.86.98.52.8-2.81.52.92.02.7-2.92.7-2.82.6-2.6-2.8-2.6
Light reinforcement 20.60.81.00.9-0.90.60.80.41.0-1.01.0-1.00.9-0.9-0.9-1.0
Reaction time number correct1.31.92.51.4-1.40.91.40.71.5-1.51.5-1.41.5-1.5-1.6-1.4
Reaction time mean minus median3.14.06.7-1.91.7-1.4-2.1-2.6-2.12.0-2.12.1-1.91.92.21.9
Reaction time mean minus median AUC2.22.85.5-1.61.4-1.2-1.7-2.3-1.81.7-1.71.8-1.51.51.81.6
Reaction time num false alarms3.95.37.72.3-2.31.72.72.82.2-2.22.2-2.12.3-2.3-2.6-2.0
Reaction time num false alarms AUC3.95.58.12.3-2.41.82.72.92.3-2.22.2-2.22.3-2.3-2.6-2.1
Reaction time trials correct on left1.31.92.51.4-1.40.91.40.71.5-1.51.5-1.41.5-1.5-1.6-1.4
Reaction time trials on left1.21.72.31.3-1.30.81.40.61.4-1.51.4-1.41.4-1.4-1.5-1.4
Reaction time mean8.411.513.2-3.43.3-2.9-3.3-3.6-3.53.6-3.53.6-3.33.33.33.5
Reaction time mean AUC7.39.712.2-3.13.0-2.6-3.0-3.5-3.23.3-3.23.3-3.03.03.03.2
Median of all reaction times7.810.511.8-3.33.2-2.8-3.1-3.4-3.33.4-3.43.4-3.23.23.03.4
Reaction time omissions0.40.51.8-0.60.5-0.5-0.6-1.3-0.70.7-0.70.8-0.60.60.60.7
Reaction time false alarm rate1.62.25.11.4-1.51.11.82.31.4-1.31.4-1.31.4-1.4-1.6-1.3
Reaction time premature initiation rate0.00.00.20.3-0.30.40.2-0.20.0-0.00.1-0.10.2-0.2-0.1-0.1
Reaction time premature initiations0.50.71.00.9-1.00.80.90.10.8-0.80.8-0.70.9-0.9-0.8-0.8
Std. dev. reaction times7.510.412.0-3.23.1-2.6-3.3-3.5-3.33.3-3.33.4-3.13.13.33.2
Reaction time trials completed1.21.72.31.3-1.30.81.40.61.4-1.51.4-1.41.4-1.4-1.5-1.4
Reaction time trials AUC1.21.72.21.3-1.30.91.40.61.4-1.51.4-1.31.4-1.4-1.5-1.3
Social response proportion1.41.52.8-1.11.0-1.6-1.0-1.7-1.11.0-1.11.1-1.31.31.01.2
Social responses0.10.10.8-0.1-0.1-0.50.0-0.9-0.10.1-0.10.1-0.20.2-0.10.2
Social time0.70.92.6-0.90.8-0.9-1.1-1.6-0.90.9-0.90.8-0.80.81.00.8
Conditioned locomotion0.20.32.0-0.1-0.1-0.9-0.0-1.4-0.20.1-0.20.1-0.40.40.10.3
Cocaine response after cond. corrected0.10.10.50.1-0.2-0.60.4-0.7-0.10.1-0.20.1-0.10.1-0.20.3
Cocaine response after cond. not corrected0.91.02.2-0.90.7-1.5-0.4-1.2-1.01.0-1.11.1-1.01.00.61.2
Cocaine response before conditioning1.01.21.6-1.21.3-1.1-1.0-0.4-1.21.1-1.11.2-1.11.11.11.2
Saline control response0.10.20.90.2-0.10.9-0.10.10.4-0.40.4-0.40.4-0.4-0.2-0.5
Condit. Reinf. active minus inactive responses3.84.76.1-2.12.0-1.6-2.0-2.5-2.32.3-2.32.4-2.12.12.12.3
Condit. Reinf. active-inactive response ratio2.93.03.7-1.71.6-0.9-1.8-1.9-1.91.9-1.91.9-1.71.71.91.8
Condit. Reinf. active responses1.01.42.2-1.11.0-1.0-0.9-1.5-1.31.3-1.31.3-1.21.21.01.3
Condit. Reinf. inactive responses0.00.00.20.0-0.0-0.50.30.30.0-0.1-0.00.0-0.10.1-0.10.1
Condit. Reinf. lever presses0.10.10.2-0.30.30.3-0.20.1-0.30.3-0.30.4-0.10.10.30.3
Condit. Reinf. lever reinforcers received0.91.21.7-1.00.9-1.0-0.8-1.3-1.21.2-1.21.3-1.11.10.91.3
Pavlov. Cond. lever latency0.20.30.50.6-0.6-0.00.6-0.10.6-0.60.6-0.70.4-0.4-0.7-0.6
Pavlov. Cond. magazine entry latency0.30.30.5-0.70.7-0.4-0.60.2-0.60.7-0.60.7-0.50.50.60.6
Pavlov. Cond. change in total contacts0.81.21.8-1.11.2-0.1-1.2-0.4-1.21.3-1.21.3-0.90.91.31.1
Pavlov. Cond. index score0.60.71.2-0.91.0-0.1-0.90.1-1.01.0-1.01.1-0.70.71.00.9
Pavlov. Cond. latency score0.60.71.2-0.90.9-0.3-0.9-0.1-1.01.0-1.01.1-0.70.71.00.9
Pavlov. Cond. lever contacts0.50.71.1-0.91.0-0.1-1.0-0.1-0.90.9-0.91.0-0.70.71.00.8
Pavlov. Cond. magazine entry number0.70.91.31.0-1.10.41.10.41.0-1.01.0-1.10.9-0.9-1.1-0.9
Pavlov. Cond. intertrial magazine entries0.91.21.51.2-1.20.91.10.51.2-1.11.2-1.21.1-1.1-1.2-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.6-0.70.70.1-0.60.3-0.70.7-0.70.8-0.40.40.70.6
Pavlov. Cond. response bias1.01.41.9-1.31.3-0.5-1.3-0.4-1.31.3-1.31.3-1.11.11.41.2
Conditioned reinforcement - actives0.60.60.7-0.80.8-0.7-0.7-0.4-0.80.8-0.80.8-0.80.80.80.8
Conditioned reinforcement - inactives1.01.11.7-1.21.2-0.7-1.0-0.3-1.11.3-1.11.1-1.11.11.11.1
Conditioned locomotion1.82.22.71.4-1.51.61.51.61.4-1.21.4-1.51.5-1.5-1.6-1.4
Intermittent access intake day 1-15 change1.11.12.11.0-1.00.61.01.41.0-1.11.0-1.01.0-1.0-1.0-1.0
Intermittent access intake escalation0.50.51.20.7-0.70.10.81.10.6-0.70.6-0.60.6-0.6-0.7-0.6
Intermittent access intake escalation 20.10.10.50.3-0.20.00.30.70.3-0.30.3-0.30.2-0.2-0.2-0.2
Intermitt. access day 1 inactive lever presses0.10.10.10.2-0.20.30.10.40.2-0.40.3-0.20.3-0.3-0.1-0.3
Intermitt. access day 15 inactive lever presses1.01.11.3-1.11.1-0.9-1.1-1.1-1.11.1-1.11.1-1.11.11.11.1
Intermitt. access escalation Index0.90.81.31.0-1.10.21.10.30.9-1.00.9-0.90.9-0.9-1.1-0.8
Intermittent access day 1 total infusions0.30.40.8-0.70.60.9-0.9-0.5-0.60.9-0.50.6-0.30.30.60.4
Intermittent access day 15 total infusions0.30.31.40.4-0.41.20.30.80.4-0.30.5-0.40.6-0.6-0.4-0.5
Intermittent access terminal intake (last 3 days)0.70.82.80.7-0.71.70.51.00.8-0.60.8-0.80.9-0.9-0.7-0.9
Intermittent access total infusions0.20.22.2-0.20.11.5-0.5-0.0-0.10.4-0.00.00.2-0.20.1-0.1
Intermittent access day 1 locomotion0.10.10.8-0.10.00.9-0.2-0.1-0.10.3-0.10.10.1-0.10.1-0.0
Intermittent access day 15 total locomotion0.00.00.1-0.10.10.4-0.10.2-0.20.3-0.20.2-0.00.00.10.2
Intermittent access total locomotion0.30.31.60.4-0.41.30.30.50.4-0.20.4-0.30.6-0.6-0.4-0.5
Intermittent access standard deviation0.30.31.00.6-0.50.70.51.00.5-0.60.5-0.50.6-0.6-0.4-0.5
Cocaine induced anxiety4.24.87.22.4-2.51.72.71.92.1-2.12.1-2.12.2-2.2-2.5-2.0
Post-drug Anxiety1.92.13.51.6-1.71.01.90.91.4-1.41.4-1.41.4-1.4-1.7-1.3
Baseline Anxiety2.82.93.8-1.81.9-1.3-2.0-1.7-1.71.7-1.71.7-1.71.71.91.6
Lifetime Intake0.20.22.40.1-0.11.6-0.10.20.20.10.2-0.20.4-0.4-0.2-0.3
Incentive Sensitization - Responses0.30.30.9-0.50.4-0.5-0.4-0.9-0.60.6-0.60.6-0.60.60.50.6
Incentive Sensitization - Breakpoint0.20.20.7-0.30.2-0.4-0.3-0.8-0.50.5-0.50.4-0.40.40.40.5
Progressive ratio test 1 active lever presses0.10.10.40.2-0.30.70.2-0.10.3-0.10.3-0.20.4-0.4-0.4-0.3
Progressive ratio test 1 breakpoint0.10.10.70.2-0.30.80.10.00.3-0.20.3-0.30.5-0.5-0.4-0.4
Progressive ratio test 1 inactive lever presses0.10.10.6-0.00.00.8-0.00.50.10.20.1-0.00.2-0.2-0.1-0.1
Progressive ratio test 2 active lever presses0.10.10.2-0.20.20.4-0.3-0.4-0.30.5-0.30.3-0.10.10.20.2
Progressive ratio test 2 breakpoint0.10.10.60.1-0.20.80.0-0.10.10.10.1-0.10.3-0.3-0.1-0.2
Progressive ratio test 2 inactive lever presses0.10.20.3-0.40.40.3-0.4-0.2-0.50.6-0.40.5-0.30.30.40.4
Total sessions with >9 infusions0.60.61.10.8-0.90.81.00.70.8-0.50.8-0.80.8-0.8-1.0-0.7
Short access day 1 total inactive lever presses0.00.00.10.1-0.10.30.1-0.30.0-0.00.00.00.1-0.1-0.1-0.0
Short access day 10 total inactive lever presses0.70.81.4-0.80.7-1.2-0.6-0.6-0.90.8-0.90.9-0.90.90.91.0
Short access day 1 total infusions0.20.21.40.2-0.21.2-0.00.30.20.00.3-0.20.4-0.4-0.1-0.3
Short access day 10 total infusions0.30.33.00.1-0.11.7-0.20.20.20.10.3-0.30.5-0.5-0.2-0.4
Short access total infusions0.50.63.00.6-0.61.70.40.50.6-0.30.6-0.60.8-0.8-0.6-0.7
Short access day 1 locomotion0.20.20.80.3-0.30.90.30.80.3-0.10.3-0.30.4-0.4-0.3-0.3
Short access day 10 total locomotion0.10.10.2-0.20.1-0.4-0.0-0.3-0.40.4-0.40.5-0.30.30.20.4
Short access total locomotion0.20.20.40.5-0.60.60.60.40.3-0.20.3-0.30.5-0.5-0.6-0.3
Compulsive drug intake0.10.10.40.3-0.3-0.70.40.30.3-0.40.3-0.30.1-0.1-0.3-0.2
One hour access (0.3 mA shock)0.10.10.2-0.40.4-0.1-0.4-0.2-0.30.4-0.30.3-0.30.30.30.3
One hour access (shock baseline)0.20.20.4-0.50.50.4-0.6-0.5-0.40.6-0.40.5-0.30.30.50.3
Number of responses in last shaping day0.50.51.90.5-0.51.40.51.10.6-0.30.6-0.50.8-0.8-0.7-0.6
Context. condit. distance diff. score1.01.31.71.2-1.11.01.00.81.2-1.31.2-1.31.0-1.0-1.1-1.2
Locomotion velocity, session 10.10.10.70.1-0.10.00.30.80.2-0.20.2-0.20.3-0.3-0.3-0.1
Locomotion distance, session 10.20.20.80.3-0.3-0.30.60.90.5-0.60.4-0.50.2-0.2-0.5-0.3
Locomotion velocity, session 22.02.35.91.3-1.31.21.62.41.4-1.41.4-1.41.6-1.6-1.6-1.3
Locomotion distance, session 20.40.61.20.7-0.7-0.00.91.10.8-0.90.8-0.90.6-0.6-0.8-0.6
Locomotion velocity, session 30.10.10.30.5-0.4-0.20.50.30.4-0.50.4-0.50.1-0.1-0.3-0.3
Locomotion distance, session 30.40.40.60.7-0.70.50.50.50.7-0.80.7-0.80.5-0.5-0.4-0.7
Stereotopy head waving bouts, day 30.60.71.50.8-0.80.31.01.20.8-0.80.8-0.80.8-0.8-0.9-0.7
Stereotopy head waving duration, day 30.10.10.60.2-0.2-0.10.50.80.2-0.20.2-0.20.3-0.3-0.4-0.1
Locomotion velocity, session 70.10.10.90.3-0.40.00.70.90.2-0.20.2-0.20.1-0.1-0.4-0.0
Locomotion distance, session 70.20.30.90.5-0.70.50.90.70.4-0.30.3-0.30.4-0.4-0.7-0.2
Stereotopy head waving bouts, day 70.10.10.2-0.30.3-0.3-0.20.0-0.40.4-0.40.4-0.50.50.40.5
Stereotopy head waving duration, day 70.70.81.1-0.90.9-0.9-0.8-0.6-0.90.9-0.90.9-1.01.01.01.0
Locomotion velocity, session 80.30.40.80.6-0.60.40.50.90.7-0.70.7-0.70.5-0.5-0.4-0.7
Locomotion distance, session 81.01.52.51.3-1.20.61.11.11.4-1.61.4-1.61.0-1.0-1.2-1.3
Degree of sensitization distance0.20.20.4-0.40.3-0.40.0-0.2-0.50.6-0.50.6-0.40.40.10.7
Degree of sensitization stereotypy0.20.20.4-0.30.30.2-0.5-0.2-0.40.4-0.40.5-0.50.50.60.4
Condit. Reinf. active minus inactive responses5.76.48.3-2.62.5-2.9-2.3-2.7-2.52.5-2.52.4-2.62.62.32.6
Condit. Reinf. active-inactive response ratio3.23.55.1-1.81.8-2.2-1.6-1.9-1.81.8-1.81.7-2.02.01.61.9
Condit. Reinf. active responses4.55.56.6-2.32.2-2.6-1.9-2.4-2.42.4-2.42.3-2.42.42.12.5
Condit. Reinf. inactive responses0.10.10.2-0.20.1-0.50.1-0.3-0.40.4-0.40.4-0.30.30.10.5
Incentive salience index mean3.94.75.4-2.32.3-2.0-2.3-2.2-2.12.2-2.12.1-2.22.22.12.1
Condit. Reinf. lever presses0.60.71.1-1.01.0-0.6-1.1-0.8-0.80.9-0.80.8-0.80.80.90.8
Time in familiar zone, hab. session 11.01.01.71.0-1.01.31.01.10.9-0.80.9-0.81.1-1.1-0.9-0.9
Time in novel zone, hab. session 14.54.35.2-2.12.1-1.8-2.3-2.2-2.02.1-2.02.0-2.12.12.22.0
Total zone transitions, hab. session 10.30.40.7-0.70.7-0.8-0.5-0.3-0.60.5-0.60.5-0.70.70.50.7
Total locomotion distance, hab. session 11.42.13.3-1.41.3-1.8-1.0-1.5-1.41.3-1.41.4-1.61.61.21.6
Locomotion velocity, hab. session 10.40.51.4-0.60.5-1.2-0.3-0.9-0.60.5-0.70.6-0.80.80.40.8
Time in familiar zone, hab. session 20.00.00.1-0.10.1-0.0-0.2-0.40.00.00.0-0.0-0.00.00.1-0.0
Time in novel zone, hab. session 20.00.00.00.1-0.1-0.10.1-0.10.1-0.10.0-0.10.0-0.0-0.0-0.1
Total zone transitions, hab. session 20.00.00.1-0.00.1-0.2-0.00.30.1-0.20.1-0.2-0.10.10.0-0.0
Total locomotion distance, hab. session 20.81.02.8-0.90.8-1.7-0.6-1.1-0.90.7-0.90.8-1.21.20.81.1
Locomotion velocity, hab. session 20.50.72.1-0.70.7-1.4-0.4-0.9-0.70.6-0.80.7-1.01.00.60.9
Novel to familiar place preference ratio1.81.92.3-1.41.4-1.3-1.5-1.5-1.31.3-1.31.3-1.31.31.41.2
Novelty place preference1.21.21.8-1.11.2-1.0-1.3-1.3-1.01.0-1.01.0-1.01.01.20.9
Time in novel zone, NPP test1.41.52.1-1.21.3-1.2-1.5-1.5-1.11.1-1.11.1-1.21.21.31.0
Total zone transitions, NPP test0.30.40.70.6-0.60.10.80.80.7-0.80.6-0.70.5-0.5-0.8-0.5
Total locomotion distance, NPP test0.30.40.8-0.70.7-0.9-0.6-0.8-0.50.4-0.60.5-0.70.70.60.6
Locomotion velocity, NPP test0.00.10.2-0.30.3-0.4-0.2-0.3-0.1-0.0-0.10.0-0.30.30.10.2
Pavlov. Cond. lever latency2.63.34.42.0-2.11.62.11.81.7-1.71.7-1.61.8-1.8-1.9-1.7
Pavlov. Cond. magazine entry latency3.14.04.5-2.02.0-2.0-1.9-2.1-2.01.9-2.01.9-2.12.12.02.0
Pavlov. Cond. change in total contacts2.32.43.7-1.51.5-1.9-1.4-1.6-1.51.4-1.51.4-1.71.71.51.5
Pavlov. Cond. index score2.43.03.9-1.81.9-1.4-2.0-1.9-1.71.6-1.61.6-1.81.81.81.6
Pavlov. Cond. latency score2.83.64.4-1.92.0-1.7-2.1-2.1-1.81.7-1.81.7-2.02.02.01.7
Pavlov. Cond. lever contacts1.11.32.3-1.21.4-0.9-1.5-1.4-1.01.0-1.00.9-1.11.11.20.9
Pavlov. Cond. magazine entry number4.75.97.12.4-2.42.32.42.72.4-2.42.4-2.32.6-2.6-2.5-2.4
Pavlov. Cond. intertrial magazine entries0.10.20.30.4-0.50.50.50.20.3-0.20.3-0.30.4-0.4-0.6-0.3
Pavlov. Cond. lever-magazine prob. diff.1.92.43.0-1.61.7-1.3-1.7-1.7-1.51.5-1.51.4-1.61.61.61.4
Pavlov. Cond. response bias2.02.53.2-1.61.6-1.3-1.8-1.8-1.51.5-1.51.4-1.61.61.71.4
Bone: apparent density2.33.86.2-2.22.3-1.0-2.5-1.4-2.02.0-1.92.0-1.81.82.31.7
Bone surface0.71.21.8-1.31.3-0.4-1.3-0.6-1.21.2-1.11.2-1.01.01.21.1
Bone volume2.23.75.0-2.12.1-1.2-2.2-1.4-2.02.0-1.92.0-1.91.92.21.8
Bone: connectivity density0.20.31.0-0.70.80.2-1.0-0.1-0.50.6-0.50.6-0.30.30.80.4
Bone: cortical apparent density8.310.812.33.3-3.43.13.43.23.2-3.03.2-3.13.5-3.5-3.5-3.1
Bone: cortical area0.00.00.10.1-0.20.10.3-0.2-0.00.1-0.10.0-0.00.0-0.20.1
Bone: cortical porosity2.32.43.7-1.71.8-1.6-1.9-1.4-1.51.3-1.41.4-1.51.51.81.3
Bone: cortical porosity3.23.54.9-2.02.1-1.9-2.2-1.8-1.81.6-1.71.7-1.81.82.11.7
Bone: cortical thickness1.72.73.31.7-1.81.61.71.31.7-1.51.6-1.71.7-1.7-1.7-1.6
Bone: cortical thickness0.00.00.1-0.10.00.2-0.00.3-0.10.2-0.10.10.0-0.00.00.1
Bone: cortical tissue density8.110.612.13.2-3.43.13.43.23.2-3.03.2-3.13.4-3.4-3.5-3.1
Bone: elastic displacement0.10.10.5-0.20.30.7-0.6-0.3-0.00.00.0-0.00.0-0.00.3-0.2
Bone: elastic work1.62.12.8-1.61.7-0.8-1.7-1.5-1.51.5-1.41.5-1.31.31.51.4
Bone: endosteal estimation4.69.911.0-3.23.2-3.2-2.9-2.9-3.23.1-3.23.2-3.33.33.03.3
Bone: endosteal perimeter1.83.74.4-1.91.8-1.7-1.6-1.9-2.02.0-2.02.0-2.12.11.82.1
Bone: final force0.91.52.7-1.00.9-1.6-0.7-1.5-1.21.2-1.21.2-1.31.30.91.4
Bone: final moment0.50.71.4-0.70.6-1.2-0.4-1.2-0.80.8-0.90.8-1.01.00.61.0
Bone: marrow area4.39.310.4-3.13.1-3.1-2.8-2.8-3.13.0-3.13.1-3.23.22.93.2
Bone: maximum diameter0.00.00.0-0.1-0.00.10.1-0.2-0.10.1-0.10.1-0.10.1-0.10.2
Bone: maximum force2.03.54.3-1.81.7-1.8-1.5-2.1-2.02.0-2.01.9-1.91.91.72.0
Bone: maximum moment1.32.22.9-1.41.3-1.3-1.2-1.7-1.51.5-1.61.5-1.51.51.41.6
Bone: minimum diameter0.61.11.5-0.90.7-1.0-0.7-1.2-1.11.0-1.11.1-1.21.20.91.2
Bone: periosteal estimation2.24.65.2-2.12.0-2.0-1.8-2.2-2.22.2-2.22.2-2.32.32.02.3
Bone: periosteal perimeter0.91.52.1-1.21.1-1.0-1.0-1.4-1.31.3-1.31.3-1.31.31.11.4
Bone: post-yield work1.41.92.5-1.41.2-1.1-1.2-1.6-1.51.5-1.51.5-1.21.21.31.5
Bone: stiffness1.52.33.1-1.51.3-1.7-1.0-1.5-1.61.7-1.61.6-1.61.61.31.8
Bone: tissue strength0.00.00.30.2-0.20.50.1-0.20.0-0.00.00.00.1-0.1-0.1-0.1
Bone: trabecular number1.11.62.6-1.41.4-0.5-1.6-0.9-1.41.4-1.31.4-1.11.11.51.2
Bone: trabecular spacing0.20.31.50.4-0.5-1.20.90.20.3-0.40.3-0.4-0.20.2-0.60.0
Bone: trabecular thickness2.73.25.8-1.92.0-0.3-2.4-1.7-1.82.0-1.81.9-1.51.52.21.5
Bone: trabecular tissue density0.20.30.6-0.40.3-0.8-0.1-0.4-0.60.6-0.60.6-0.50.50.30.7
Breakpoint value in progressive ratio session0.60.61.2-0.70.6-1.1-0.4-0.6-0.90.9-0.90.9-0.80.80.61.0
Distance traveled before self-admin6.57.07.8-2.52.5-2.4-2.5-2.8-2.72.8-2.72.7-2.62.62.72.7
Distance traveled after self-admin2.02.24.0-1.31.2-2.0-1.2-1.9-1.51.4-1.51.5-1.41.41.31.5
Delta time in closed arm before/after self-admin1.01.01.21.0-1.00.81.01.11.0-1.01.0-1.01.0-1.0-1.0-1.0
Delta time in open arm before/after self-admin4.94.75.5-2.12.1-2.1-2.3-2.3-2.12.0-2.12.1-2.22.22.32.1
Diff in mean of infusions in LGA sessions1.21.41.9-1.11.0-1.0-1.0-1.1-1.31.4-1.31.2-1.11.11.21.3
Extinction: sum of active levers before priming2.22.23.9-1.41.4-2.0-1.2-1.5-1.51.4-1.51.5-1.51.51.31.6
Active lever presses in extinction session 60.40.40.6-0.50.5-0.7-0.5-0.7-0.60.6-0.60.6-0.60.60.60.6
Delta distance traveled before/after self-admin0.70.71.20.9-0.90.11.10.70.9-1.00.8-0.80.8-0.8-1.0-0.8
Delta ambulatory time before/after self-admin0.91.01.71.0-1.10.21.30.91.0-1.21.0-0.90.9-0.9-1.2-0.9
Time in closed arm before self-admin3.13.64.4-2.02.0-1.4-2.1-1.8-1.91.9-1.91.8-1.91.92.01.8
Time in closed arm after self-admin0.20.20.3-0.50.6-0.5-0.40.1-0.40.4-0.40.5-0.50.50.50.5
Time in open arm before self-admin3.73.95.52.0-2.21.82.31.71.9-1.71.9-1.92.1-2.1-2.3-1.8
Time in open arm after self-admin2.93.24.6-1.71.7-1.7-1.7-2.1-1.81.8-1.81.8-1.81.81.81.8
Sum of active levers in priming session hrs 5-63.23.16.6-1.61.5-2.6-1.2-2.0-1.81.6-1.81.8-1.71.71.41.9
Time to tail flick, vehicle, before self-admin0.80.80.90.9-0.90.80.90.80.9-0.80.9-0.90.9-0.9-0.9-0.9
Time to tail flick, vehicle, after self-admin0.20.20.4-0.50.5-0.6-0.4-0.3-0.40.4-0.40.4-0.50.50.30.4
Time to tail flick, test, before self-admin1.01.01.81.0-1.10.31.40.91.0-1.00.9-0.91.1-1.1-1.3-0.8
Time to tail flick, test, after self-admin1.71.72.41.2-1.11.21.21.51.4-1.31.4-1.31.3-1.3-1.4-1.3
Delta time to tail flick, vehicle, before/after SA1.21.11.3-1.11.2-1.1-1.0-0.9-1.01.0-1.01.0-1.21.21.01.0
Delta time to tail flick, test, before/after SA0.10.10.6-0.00.20.8-0.50.30.3-0.20.3-0.30.1-0.10.2-0.4
Ambulatory time before self-admin5.25.46.9-2.22.1-2.1-2.2-2.6-2.42.5-2.42.3-2.32.32.42.4
Ambulatory time after self-admin0.30.41.1-0.50.4-1.1-0.3-0.8-0.60.5-0.60.6-0.60.60.40.7
Total heroin consumption0.81.01.4-1.11.2-1.1-1.2-0.6-0.90.8-0.91.0-1.01.01.10.9
Area under the delay curve0.00.00.4-0.00.00.6-0.00.20.10.00.1-0.20.2-0.2-0.2-0.1
Delay disc. indifference point, 0s delay0.10.10.5-0.30.40.7-0.50.3-0.00.10.0-0.00.1-0.10.2-0.1
Delay disc. indifference point, 16s delay0.30.30.6-0.70.6-0.2-0.6-0.3-0.60.8-0.60.6-0.60.60.50.6
Delay disc. indifference point, 2s delay0.10.10.8-0.20.20.9-0.30.00.10.00.1-0.10.2-0.2-0.0-0.2
Delay disc. indifference point, 24s delay0.10.10.30.4-0.40.50.30.10.3-0.20.3-0.30.3-0.3-0.4-0.3
Delay disc. indifference point, 4s delay0.60.61.70.6-0.71.30.50.30.8-0.60.8-0.80.9-0.9-0.8-0.8
Delay disc. indifference point, 8s delay0.20.20.4-0.50.5-0.3-0.4-0.3-0.50.7-0.50.5-0.50.50.40.6
Delay discount exponential model param0.00.10.4-0.00.1-0.6-0.0-0.2-0.20.0-0.20.2-0.20.20.20.2
Delay discount hyperbolic model param0.10.10.6-0.20.2-0.8-0.1-0.3-0.30.2-0.30.4-0.40.40.40.3
Fecal boli incidents, locomotor time 10.20.20.70.3-0.20.90.20.80.3-0.30.3-0.30.4-0.4-0.2-0.4
Change in fecal boli incidents, locomotor task0.10.10.50.1-0.2-0.30.0-0.70.1-0.20.1-0.1-0.10.1-0.0-0.1
Time >=10cm from walls, locomotor time 10.00.00.1-0.0-0.1-0.20.2-0.30.10.00.0-0.3-0.00.0-0.30.0
Bouts of movement, locomotor time 11.61.83.71.3-1.31.91.11.01.3-1.21.3-1.21.5-1.5-1.3-1.3
Total resting periods, locomotor time 12.02.23.81.4-1.52.01.31.21.4-1.41.4-1.41.6-1.6-1.5-1.5
Rest time, locomotor task time 10.80.91.30.9-0.91.20.60.80.9-0.91.0-0.91.0-1.0-0.7-1.0
Distance moved, locomotor task time 10.30.31.6-0.50.4-1.3-0.2-0.6-0.50.4-0.50.3-0.60.60.20.6
Vertical activity count, locomotor time 10.20.21.6-0.20.2-1.3-0.0-0.5-0.20.1-0.20.1-0.50.50.10.3
Time >=10cm from walls, locomotor time 21.61.72.1-1.21.2-1.3-1.3-1.4-1.31.2-1.31.4-1.41.41.41.3
Bouts of movement, locomotor time 24.04.35.22.1-2.21.92.21.72.0-2.02.0-2.02.2-2.2-2.3-2.0
Total resting periods, locomotor time 24.24.55.22.1-2.12.22.12.02.1-2.02.1-2.12.3-2.3-2.3-2.1
Rest time, locomotor task time 21.61.83.41.4-1.31.80.91.21.3-1.31.4-1.31.5-1.5-1.0-1.5
Distance moved, locomotor task time 21.01.12.5-1.11.0-1.6-0.7-0.8-1.00.9-1.11.0-1.11.10.81.2
Vertical activity count, locomotor time 20.10.10.9-0.00.0-0.90.2-0.10.0-0.1-0.0-0.0-0.20.2-0.10.1
Weight adjusted by age0.40.40.8-0.50.4-0.5-0.3-0.9-0.70.8-0.70.6-0.60.60.40.8
Seeking ratio, delayed vs. immediate footshock2.73.13.3-1.81.8-1.5-1.7-1.7-1.81.8-1.81.8-1.81.71.81.8
Locomotion in novel chamber1.11.32.21.2-1.40.91.51.01.1-1.11.1-1.11.1-1.1-1.3-1.0
Locomotion in novel chamber post-restriction0.50.60.90.8-0.90.60.90.40.8-0.80.7-0.70.8-0.8-1.0-0.7
Progressive ratio0.10.20.80.4-0.5-0.30.90.50.2-0.20.2-0.20.2-0.2-0.6-0.0
Food seeking constrained by brief footshock0.10.10.80.0-0.2-0.90.4-0.5-0.10.0-0.10.2-0.10.1-0.20.2
Seeking ratio, punishment vs. effort0.10.10.5-0.30.3-0.3-0.5-0.7-0.30.2-0.20.3-0.30.30.40.2
Run reversals in cocaine runway, females0.10.10.20.3-0.4-0.10.4-0.40.2-0.10.1-0.20.1-0.1-0.4-0.1
Run reversals in cocaine runway, males0.70.71.30.9-1.00.31.10.60.8-0.80.8-0.80.8-0.8-1.1-0.7
Latency to leave start box in cocaine runway6.77.311.32.6-2.52.52.63.42.7-2.72.7-2.72.7-2.7-2.6-2.7
Latency to leave start box in cocaine runway, F4.14.55.52.0-1.92.31.62.32.2-2.22.2-2.22.2-2.2-1.8-2.3
Latency to leave start box in cocaine runway, M2.42.36.11.4-1.50.82.02.51.4-1.31.3-1.31.3-1.4-1.7-1.1
Cd content in liver0.80.81.2-0.90.9-1.0-0.6-0.4-1.01.0-1.01.0-0.90.90.81.1
Co content in liver0.20.20.5-0.60.7-0.2-0.6-0.1-0.50.5-0.40.5-0.40.40.50.4
Cu content in liver1.41.62.6-1.61.6-0.0-1.5-0.6-1.41.5-1.41.5-1.00.91.21.3
Fe content in liver3.44.14.8-2.02.0-2.1-2.0-1.9-2.02.0-2.02.0-2.22.12.12.0
K content in liver1.01.01.70.9-0.81.10.71.31.0-1.11.0-1.00.9-0.9-0.8-1.0
Mg content in liver0.80.91.21.0-1.00.80.80.91.0-1.11.0-1.10.8-0.8-0.8-1.0
Mn content in liver0.40.50.90.7-0.61.00.20.60.7-0.80.8-0.80.6-0.7-0.3-0.9
Na content in liver0.30.31.80.3-0.31.30.10.60.4-0.40.5-0.40.7-0.7-0.3-0.6
Rb content in liver0.70.82.00.9-1.1-0.41.40.80.8-0.80.8-0.80.9-0.9-1.2-0.6
Se content in liver0.00.00.10.1-0.1-0.3-0.0-0.30.2-0.30.2-0.2-0.10.0-0.0-0.2
Sr content in liver0.30.30.60.4-0.40.80.50.70.5-0.40.5-0.40.6-0.6-0.6-0.4
Zn content in liver0.80.91.51.2-1.20.31.21.01.0-1.00.9-1.00.7-0.7-1.0-0.9