Hub : Genes

Casp7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000056216 0.14 0.07 9.9e-12 0.1 0.02 0.09 0.07 9.3e-11 6.3e-03 3.4e-10 6.9e-08
2 Brain gene expression ENSRNOG00000056216 0.13 0.07 2.1e-14 0.12 0.17 0.16 0.16 4.7e-11 1.9e-15 8.0e-15 1.4e-14
3 Brain mRNA stability ENSRNOG00000056216 0.12 0.08 6.6e-06 0.04 0.04 0.04 0.04 8.2e-05 5.0e-05 2.8e-04 2.0e-04
4 Eye gene expression ENSRNOG00000056216 0.51 0.23 3.9e-03 0.05 0.12 0.01 0.05 6.2e-02 7.2e-03 2.0e-01 6.7e-02
5 LHb gene expression ENSRNOG00000056216 0.12 0.09 9.4e-03 0.12 0.08 0.08 0.1 1.1e-03 6.0e-03 6.5e-03 2.8e-03
6 Liver alternative TSS ENSRNOT00000080511 0.02 0.02 3.4e-03 0.01 0.01 0 0.01 8.9e-03 8.5e-03 2.6e-01 2.3e-02
7 Liver alternative TSS ENSRNOT00000103804 0.02 0.01 4.2e-03 0.01 0.01 -0 0.01 1.3e-02 1.3e-02 4.9e-01 4.5e-02
8 NAcc gene expression ENSRNOG00000056216 0.21 0.11 1.4e-09 0.1 0.1 0.12 0.1 5.4e-08 7.3e-08 3.5e-09 4.8e-08
9 NAcc mRNA stability ENSRNOG00000056216 0.07 0.05 9.2e-04 0.04 0.04 0.05 0.04 6.2e-04 5.4e-04 1.1e-04 1.2e-03
10 OFC gene expression ENSRNOG00000056216 0.18 0.14 8.8e-03 0.02 0.01 0 -0.01 1.1e-01 1.4e-01 2.9e-01 4.8e-01
11 PL gene expression ENSRNOG00000056216 0.12 0.06 2.6e-08 0.1 0.1 0.1 0.1 7.8e-08 4.0e-08 2.6e-08 3.7e-08
12 PL mRNA stability ENSRNOG00000056216 0.09 0.05 4.7e-05 0.07 0.06 0.07 0.06 4.2e-06 2.9e-05 4.6e-06 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail8.126.239.25.05.65.15.85.0-6.14.86.33.45.05.91.5
BMI without tail3.57.311.82.62.92.83.42.2-3.32.03.32.12.53.30.7
Body weight9.339.365.56.16.76.17.15.8-7.25.98.14.56.17.42.1
Epididymis fat weight13.932.450.14.85.75.66.75.3-6.75.97.14.74.57.12.7
Glucose5.07.711.32.83.13.12.42.7-2.93.43.01.92.83.20.8
Heart weight2.53.65.71.82.31.51.92.2-2.42.22.01.01.72.30.6
Left kidney weight3.29.123.74.93.70.21.82.1-2.82.33.8-0.24.82.9-2.1
Right kidney weight4.713.325.55.14.71.62.63.5-4.03.44.60.24.93.9-1.5
Tail length0.30.82.30.40.50.91.40.2-0.91.00.71.40.31.50.6
Length with tail2.38.415.32.73.12.53.22.6-3.32.93.92.22.73.71.0
Length without tail5.211.317.63.33.83.03.33.7-3.83.74.21.93.43.81.1
Liver weight, left3.96.310.11.42.42.63.22.4-3.12.33.02.41.43.21.8
Liver weight, right7.011.718.13.13.73.24.03.3-4.13.44.02.43.24.31.2
Parametrial fat weight8.115.926.62.03.54.55.23.8-4.74.04.53.82.05.03.3
Retroperitoneal fat weight12.240.462.85.66.66.37.36.0-7.46.47.94.85.67.82.8
Intraocular pressure3.34.68.50.62.22.22.62.9-2.92.61.51.60.52.62.0
Extensor digitorum longus weight0.52.16.00.50.81.91.91.0-1.40.82.41.80.51.41.5
Soleus weight3.510.319.43.73.72.32.82.9-3.53.74.41.53.73.7-0.0
Tibialis anterior weight0.10.41.3-1.1-0.30.50.30.1-0.1-0.30.70.4-1.1-0.01.0
Tibia length1.74.79.33.02.71.41.82.0-2.42.12.30.33.02.4-0.2
Number of licking bursts0.81.02.7-0.10.31.01.50.4-0.90.71.31.6-0.21.11.1
Food consumed during 24 hour testing period0.10.10.40.60.10.2-0.2-0.20.2-0.20.50.10.6-0.1-0.6
Times rat made contact with spout0.60.72.31.00.9-0.00.70.5-0.90.71.50.30.90.8-0.4
Mean time between licks in bursts0.10.20.5-0.5-0.30.40.60.0-0.1-0.0-0.00.7-0.50.30.7
Mean num. licks in bursts0.60.82.21.20.8-0.8-0.80.3-0.10.20.0-1.41.2-0.2-1.5
Std. dev. time between licks in bursts0.40.51.3-1.1-0.9-0.90.4-0.70.3-0.7-0.7-0.2-1.1-0.30.4
Water consumed over 24 hours0.70.82.31.51.00.10.20.4-0.50.71.3-0.11.50.6-1.1
Indifference point 0 sec3.45.58.11.22.32.62.72.4-2.82.82.71.91.32.81.7
Indifference point AUC0.40.51.5-1.1-0.10.21.00.2-0.70.4-0.40.5-1.20.41.0
Indifference point function ln k0.20.31.00.90.40.3-0.50.20.10.10.6-0.51.0-0.1-0.3
Indifference point function log k0.20.31.00.90.40.3-0.50.20.10.10.6-0.51.0-0.1-0.3
Delay discounting total patch changes 0 sec3.45.58.11.02.12.72.82.4-2.82.82.62.01.12.81.8
Delay discounting total patch changes 12 sec1.11.54.0-0.30.51.42.00.8-1.31.01.21.6-0.41.41.6
Delay discounting total patch changes 18 sec2.43.16.8-0.41.21.82.61.7-2.31.91.01.9-0.42.12.2
Delay discounting total patch changes 24 sec2.12.65.7-0.70.71.62.41.2-1.81.61.42.1-0.71.82.2
Delay discounting total patch changes 6 sec4.26.410.20.82.32.73.22.8-3.23.02.42.30.83.12.2
Delay discounting time to switch 0 sec0.30.51.0-0.2-0.7-0.8-0.9-0.81.0-0.9-0.3-0.2-0.3-0.8-0.5
Delay discounting water rate 0 sec0.50.81.50.71.01.10.91.1-1.11.20.50.20.71.00.4
Delay discounting water rate 12 sec1.21.74.90.40.92.21.71.2-1.41.40.81.10.41.31.6
Delay discounting water rate 18 sec0.60.81.51.21.20.50.60.8-1.00.81.2-0.01.20.9-0.4
Delay discounting water rate 24 sec1.21.72.81.71.50.61.41.1-1.51.21.60.21.61.5-0.4
Delay discounting water rate 6 sec0.50.72.21.41.00.40.40.7-0.71.00.2-0.41.50.6-0.7
Locomotor activity1.42.34.61.61.91.30.81.7-1.51.72.20.71.81.7-0.2
Locomotor testing distance1.82.95.62.32.30.90.42.2-1.62.11.5-0.12.41.6-0.9
Locomotor testing rearing1.01.63.11.61.60.90.61.6-1.21.51.40.41.81.2-0.6
Light reinforcement 11.22.34.7-1.2-1.7-1.7-1.2-2.21.8-2.0-1.4-0.7-1.1-1.6-0.7
Light reinforcement 22.22.95.6-1.0-1.8-2.1-1.4-2.22.0-2.4-1.5-1.2-1.0-1.7-1.4
Reaction time number correct0.81.12.10.70.81.31.50.9-1.21.11.11.00.51.20.9
Reaction time mean minus median0.30.41.70.01.10.00.11.3-1.00.60.40.20.20.70.1
Reaction time mean minus median AUC0.50.61.50.81.2-0.30.11.1-0.90.70.9-0.11.00.8-0.7
Reaction time num false alarms0.10.10.3-0.1-0.2-0.50.2-0.30.1-0.50.1-0.3-0.20.0-0.5
Reaction time num false alarms AUC0.10.10.60.2-0.0-0.60.0-0.2-0.0-0.20.1-0.50.00.1-0.8
Reaction time trials correct on left0.81.12.10.70.81.31.50.9-1.21.11.11.00.51.20.9
Reaction time trials on left0.81.22.30.70.91.31.51.0-1.31.11.11.10.51.30.9
Reaction time mean0.30.41.40.30.90.2-0.41.2-0.61.0-0.2-0.20.40.5-0.3
Reaction time mean AUC0.10.20.6-0.20.5-0.0-0.60.8-0.10.6-0.4-0.3-0.10.1-0.2
Median of all reaction times0.30.41.00.50.80.2-0.51.0-0.31.0-0.3-0.50.60.3-0.5
Reaction time omissions0.30.41.20.20.50.51.00.6-0.8-0.01.10.50.40.70.6
Reaction time false alarm rate0.30.41.0-0.4-0.6-1.0-0.5-0.70.6-0.8-0.5-0.7-0.4-0.5-0.8
Reaction time premature initiation rate0.50.71.81.11.1-0.4-0.10.5-0.61.20.5-0.81.30.5-1.0
Reaction time premature initiations1.11.63.31.61.70.30.71.2-1.41.81.1-0.21.71.3-0.6
Std. dev. reaction times1.21.74.70.61.90.70.82.2-1.81.80.80.50.81.60.2
Reaction time trials completed0.81.22.30.70.91.31.51.0-1.31.11.11.10.51.30.9
Reaction time trials AUC0.91.22.30.70.91.31.51.1-1.31.21.11.00.51.30.9
Social response proportion2.62.97.32.72.20.30.71.4-1.61.32.4-0.22.61.3-1.1
Social responses4.15.38.91.62.71.82.42.8-3.02.62.51.61.52.91.1
Social time1.41.93.81.61.80.60.91.5-1.51.51.90.51.41.6-0.3
Conditioned locomotion0.10.10.4-0.2-0.2-0.5-0.6-0.30.4-0.2-0.2-0.5-0.2-0.3-0.3
Cocaine response after cond. corrected2.93.26.6-0.5-1.0-2.6-2.3-1.11.7-1.4-2.3-2.4-0.5-1.9-2.1
Cocaine response after cond. not corrected3.13.46.4-0.9-1.4-2.3-2.4-1.31.9-1.7-2.5-2.1-0.9-2.1-1.6
Cocaine response before conditioning0.50.62.2-0.9-0.81.00.3-0.40.4-0.2-0.21.1-0.9-0.01.5
Saline control response0.20.31.1-0.20.1-0.7-1.00.40.20.1-0.6-1.0-0.2-0.5-0.8
Condit. Reinf. active minus inactive responses1.61.95.7-1.20.71.61.31.9-1.61.3-0.01.1-1.21.02.4
Condit. Reinf. active-inactive response ratio0.50.51.8-1.1-0.10.50.60.6-0.60.1-0.20.2-1.10.11.3
Condit. Reinf. active responses2.94.19.0-0.81.42.52.12.7-2.42.20.72.0-0.81.93.0
Condit. Reinf. inactive responses1.82.34.1-0.11.11.91.41.9-1.61.90.71.9-0.11.62.0
Condit. Reinf. lever presses0.71.02.3-0.60.41.01.40.8-1.10.80.41.5-0.71.11.5
Condit. Reinf. lever reinforcers received2.12.97.0-0.91.11.91.82.3-2.01.80.41.7-0.91.62.6
Pavlov. Cond. lever latency0.70.92.51.20.1-0.5-1.3-0.50.8-0.50.2-1.21.3-0.7-1.6
Pavlov. Cond. magazine entry latency1.41.63.50.40.81.11.80.7-1.31.21.91.80.41.60.9
Pavlov. Cond. change in total contacts1.01.43.0-0.70.61.01.61.3-1.41.20.51.4-0.81.31.7
Pavlov. Cond. index score1.31.73.6-0.20.91.11.91.2-1.61.41.21.6-0.21.61.2
Pavlov. Cond. latency score1.31.63.7-0.20.81.11.91.1-1.61.31.31.7-0.21.61.3
Pavlov. Cond. lever contacts0.50.71.7-0.40.40.51.30.6-1.00.90.21.1-0.51.01.0
Pavlov. Cond. magazine entry number1.21.53.2-0.4-0.8-1.1-1.7-0.71.3-1.1-1.8-1.7-0.3-1.5-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.40.30.20.70.40.2-0.30.20.40.50.30.30.4
Pavlov. Cond. lever-magazine prob. diff.1.21.53.0-0.11.00.91.71.3-1.61.41.11.4-0.11.61.0
Pavlov. Cond. response bias1.01.33.0-0.20.71.01.70.9-1.41.40.71.6-0.21.51.3
Conditioned reinforcement - actives0.80.84.2-0.6-0.1-2.0-1.0-0.00.30.0-0.3-1.4-0.6-0.5-1.3
Conditioned reinforcement - inactives0.50.51.40.00.80.30.61.0-0.91.20.90.50.21.00.4
Conditioned locomotion0.91.14.7-0.6-0.3-2.2-1.3-0.40.6-0.5-0.3-1.6-0.6-0.9-1.4
Intermittent access intake day 1-15 change2.92.95.61.11.81.81.52.0-1.92.41.51.51.22.01.3
Intermittent access intake escalation3.53.56.41.82.41.31.32.2-2.12.51.90.92.02.20.3
Intermittent access intake escalation 21.81.83.31.71.70.50.71.5-1.41.81.30.41.71.6-0.2
Intermitt. access day 1 inactive lever presses1.92.04.20.31.01.82.01.1-1.61.21.91.60.41.71.2
Intermitt. access day 15 inactive lever presses0.10.10.2-0.00.40.10.20.5-0.40.50.40.30.10.30.1
Intermitt. access escalation Index0.20.10.50.60.20.20.2-0.1-0.0-0.10.70.50.70.2-0.1
Intermittent access day 1 total infusions0.30.31.1-1.0-0.1-1.00.20.1-0.20.10.90.1-1.00.2-0.2
Intermittent access day 15 total infusions1.01.23.20.21.20.00.91.2-1.31.51.80.90.41.40.2
Intermittent access terminal intake (last 3 days)0.40.51.50.00.8-0.30.50.8-0.81.01.20.40.10.90.1
Intermittent access total infusions0.60.61.5-0.30.9-0.50.51.2-1.11.21.20.1-0.30.9-0.0
Intermittent access day 1 locomotion0.50.52.2-0.3-0.1-1.5-0.5-0.40.3-0.50.4-0.8-0.1-0.5-1.2
Intermittent access day 15 total locomotion2.12.24.50.61.81.31.32.1-1.92.01.70.90.81.80.6
Intermittent access total locomotion0.50.51.40.50.9-0.8-0.30.8-0.50.50.5-1.10.60.2-1.2
Intermittent access standard deviation1.51.64.1-0.60.40.81.60.9-1.21.31.31.8-0.61.52.0
Cocaine induced anxiety4.45.18.4-0.2-2.2-2.3-2.5-2.92.9-2.7-2.3-2.0-0.4-2.8-2.0
Post-drug Anxiety1.01.12.10.4-0.9-1.2-1.0-1.41.2-1.2-0.9-0.90.1-1.2-1.4
Baseline Anxiety5.86.19.80.82.52.62.92.7-3.12.72.82.41.03.01.7
Lifetime Intake0.70.71.7-0.31.0-0.70.51.3-1.21.31.30.1-0.31.0-0.1
Incentive Sensitization - Responses1.31.32.40.51.30.81.01.5-1.41.51.50.80.61.40.5
Incentive Sensitization - Breakpoint1.41.42.60.41.41.01.11.6-1.51.61.40.90.51.40.7
Progressive ratio test 1 active lever presses0.70.71.60.11.1-0.80.21.3-1.01.30.8-0.20.10.8-0.8
Progressive ratio test 1 breakpoint0.30.30.8-0.40.6-0.9-0.10.8-0.60.80.4-0.3-0.40.4-0.5
Progressive ratio test 1 inactive lever presses0.20.20.5-0.00.5-0.00.20.5-0.40.70.50.60.10.6-0.1
Progressive ratio test 2 active lever presses1.71.83.70.61.80.00.91.9-1.81.91.90.50.61.6-0.1
Progressive ratio test 2 breakpoint1.41.63.40.41.60.00.91.8-1.71.81.70.50.41.6-0.0
Progressive ratio test 2 inactive lever presses1.21.33.20.21.00.91.21.2-1.31.31.81.20.31.41.2
Total sessions with >9 infusions3.63.98.71.72.80.11.03.0-2.52.91.8-0.31.72.1-0.9
Short access day 1 total inactive lever presses0.50.61.20.70.70.50.80.5-0.70.61.11.00.70.90.2
Short access day 10 total inactive lever presses0.60.71.30.50.81.20.80.9-0.90.90.90.70.51.00.6
Short access day 1 total infusions0.50.50.90.81.0-0.60.11.0-0.70.90.8-0.30.70.6-0.8
Short access day 10 total infusions0.30.41.8-0.60.3-1.4-0.40.6-0.30.50.1-0.6-0.60.1-0.8
Short access total infusions0.40.41.4-0.20.7-1.20.00.9-0.70.80.7-0.4-0.30.5-0.7
Short access day 1 locomotion0.40.41.1-0.10.8-0.7-0.01.1-0.81.00.6-0.3-0.20.5-0.7
Short access day 10 total locomotion0.80.92.81.51.10.40.30.7-0.70.90.4-0.31.70.7-1.1
Short access total locomotion0.90.93.10.91.0-1.2-0.30.7-0.60.80.5-1.31.00.3-1.8
Compulsive drug intake0.40.41.3-1.1-0.70.10.2-0.60.3-0.6-0.30.7-0.9-0.10.8
One hour access (0.3 mA shock)2.02.34.4-0.51.01.01.71.5-1.61.62.12.0-0.51.91.7
One hour access (shock baseline)1.41.73.90.71.60.41.01.8-1.61.82.00.60.61.60.2
Number of responses in last shaping day0.20.20.60.30.3-0.5-0.20.3-0.20.30.7-0.60.20.1-0.5
Context. condit. distance diff. score0.70.92.50.4-0.9-0.5-0.8-1.61.3-1.2-0.6-0.40.4-1.0-1.1
Locomotion velocity, session 11.11.23.0-1.4-0.8-1.1-1.2-0.10.7-0.6-1.7-1.3-1.4-1.1-0.4
Locomotion distance, session 10.81.03.30.20.5-1.2-1.40.60.1-0.2-0.8-1.80.2-0.8-1.8
Locomotion velocity, session 21.01.24.80.80.4-1.1-1.5-0.00.5-0.1-0.4-1.80.9-0.8-2.2
Locomotion distance, session 20.81.12.11.31.5-0.60.61.2-1.31.10.7-0.71.21.0-1.2
Locomotion velocity, session 30.40.52.00.60.6-0.8-0.80.3-0.10.1-0.3-1.10.6-0.4-1.4
Locomotion distance, session 30.80.83.71.20.7-0.9-0.90.10.10.10.0-1.21.2-0.3-1.9
Stereotopy head waving bouts, day 30.10.20.5-0.20.30.2-0.00.6-0.30.6-0.70.2-0.20.30.7
Stereotopy head waving duration, day 30.50.62.3-1.2-0.50.2-0.50.20.30.0-1.50.1-1.2-0.31.1
Locomotion velocity, session 70.10.20.40.30.30.40.60.1-0.40.20.50.30.30.50.5
Locomotion distance, session 70.10.10.30.5-0.2-0.2-0.1-0.50.3-0.4-0.3-0.20.4-0.1-0.4
Stereotopy head waving bouts, day 70.10.10.6-0.2-0.00.20.50.0-0.20.40.40.4-0.10.50.8
Stereotopy head waving duration, day 70.60.81.30.00.70.91.11.0-1.01.11.00.70.11.11.1
Locomotion velocity, session 81.72.14.5-0.5-1.6-1.2-1.3-1.91.8-2.1-1.6-0.8-0.6-1.8-0.9
Locomotion distance, session 80.81.23.60.8-0.5-1.3-0.9-1.31.0-1.2-0.8-1.10.7-0.9-1.9
Degree of sensitization distance1.01.02.3-1.1-1.40.30.6-1.10.7-0.8-0.71.2-1.2-0.11.5
Degree of sensitization stereotypy0.20.20.7-0.2-0.10.20.7-0.1-0.20.20.80.4-0.10.40.7
Condit. Reinf. active minus inactive responses0.10.10.5-0.20.1-0.6-0.50.30.0-0.0-0.3-0.4-0.2-0.4-0.7
Condit. Reinf. active-inactive response ratio0.10.10.4-0.4-0.1-0.3-0.50.10.2-0.50.1-0.3-0.4-0.6-0.3
Condit. Reinf. active responses0.30.41.7-0.10.80.20.31.3-1.01.00.1-0.1-0.10.50.0
Condit. Reinf. inactive responses0.80.92.7-0.11.00.80.91.6-1.41.6-0.20.2-0.11.10.8
Incentive salience index mean0.50.61.4-0.6-0.2-1.2-1.00.10.3-0.4-0.7-1.1-0.6-0.9-1.0
Condit. Reinf. lever presses0.40.61.3-0.8-0.2-1.0-1.00.30.3-0.4-0.7-1.2-0.8-0.9-0.7
Time in familiar zone, hab. session 10.20.20.90.20.1-0.0-0.90.20.3-0.4-0.1-0.90.2-0.6-0.5
Time in novel zone, hab. session 10.90.92.5-0.00.30.91.60.3-0.90.90.71.6-0.01.31.1
Total zone transitions, hab. session 11.21.62.71.61.60.30.91.4-1.51.51.3-0.01.61.4-0.7
Total locomotion distance, hab. session 10.10.10.30.20.0-0.30.3-0.2-0.10.5-0.20.30.20.5-0.3
Locomotion velocity, hab. session 10.10.10.40.1-0.2-0.60.0-0.40.20.2-0.50.00.00.2-0.5
Time in familiar zone, hab. session 22.02.16.1-0.10.71.62.01.2-1.50.91.31.9-0.01.52.5
Time in novel zone, hab. session 21.11.14.30.50.0-1.1-1.4-0.40.7-0.2-0.6-1.70.5-0.8-2.1
Total zone transitions, hab. session 21.31.72.91.51.70.41.11.5-1.61.41.40.01.51.3-0.9
Total locomotion distance, hab. session 20.50.61.31.11.0-0.00.80.5-0.90.90.50.21.11.0-0.7
Locomotion velocity, hab. session 20.30.40.91.00.8-0.20.50.3-0.60.70.20.11.00.8-0.9
Novel to familiar place preference ratio0.20.20.5-0.6-0.20.60.50.0-0.10.10.50.7-0.50.10.5
Novelty place preference0.20.30.7-0.4-0.10.70.70.1-0.30.30.70.8-0.40.40.6
Time in novel zone, NPP test0.70.71.7-0.40.11.11.20.4-0.70.61.11.3-0.40.81.0
Total zone transitions, NPP test0.71.02.61.21.1-0.01.20.7-1.20.71.60.31.21.1-0.7
Total locomotion distance, NPP test0.30.51.10.90.5-0.21.1-0.0-0.70.50.80.60.81.0-0.6
Locomotion velocity, NPP test0.20.31.00.90.3-0.70.4-0.4-0.20.00.30.10.90.4-1.0
Pavlov. Cond. lever latency0.30.41.6-0.3-0.00.80.70.3-0.30.20.61.1-0.40.61.3
Pavlov. Cond. magazine entry latency0.20.30.50.70.6-0.00.60.2-0.50.70.70.60.70.7-0.1
Pavlov. Cond. change in total contacts0.10.20.60.70.30.00.0-0.1-0.00.00.4-0.20.7-0.1-0.8
Pavlov. Cond. index score0.30.30.80.80.70.20.30.3-0.50.60.70.20.90.5-0.5
Pavlov. Cond. latency score0.20.20.60.70.60.00.20.2-0.40.40.6-0.10.80.3-0.6
Pavlov. Cond. lever contacts0.10.10.4-0.00.0-0.3-0.4-0.00.1-0.1-0.3-0.60.0-0.3-0.6
Pavlov. Cond. magazine entry number1.01.22.0-1.4-1.4-0.7-0.9-1.11.2-1.4-1.2-0.5-1.4-1.20.2
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.00.4-0.1-0.10.5-0.40.30.1-0.60.00.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.60.50.20.40.2-0.50.50.60.30.70.4-0.3
Pavlov. Cond. response bias0.30.30.80.90.80.00.20.4-0.50.70.50.00.90.5-0.7
Bone: apparent density2.23.711.60.61.22.32.61.3-2.01.03.42.10.61.82.1
Bone surface0.91.64.90.90.91.51.80.6-1.30.62.21.20.91.21.1
Bone volume3.15.215.41.51.92.52.91.7-2.51.63.92.11.52.41.7
Bone: connectivity density0.20.30.9-0.2-0.20.80.6-0.3-0.1-0.40.90.6-0.20.10.9
Bone: cortical apparent density1.72.27.81.20.5-1.6-2.3-0.10.8-0.2-0.5-2.31.2-1.2-2.8
Bone: cortical area9.213.921.52.94.03.84.43.9-4.64.04.42.62.94.31.6
Bone: cortical porosity0.30.41.2-0.4-0.10.40.8-0.1-0.4-0.10.91.0-0.40.41.1
Bone: cortical porosity0.80.82.4-0.3-0.10.81.4-0.2-0.6-0.01.31.5-0.30.81.4
Bone: cortical thickness4.67.611.42.53.22.52.83.1-3.43.23.21.62.53.10.6
Bone: cortical thickness2.42.85.62.12.01.21.41.5-1.81.72.40.72.11.8-0.1
Bone: cortical tissue density1.82.47.91.00.3-1.7-2.5-0.31.1-0.4-0.7-2.31.0-1.4-2.8
Bone: elastic displacement0.10.10.3-0.4-0.40.10.2-0.50.2-0.2-0.10.5-0.4-0.10.3
Bone: elastic work1.11.43.21.81.50.50.80.9-1.21.11.5-0.01.81.0-0.8
Bone: endosteal estimation1.53.36.71.51.71.72.61.4-2.21.72.11.41.52.31.1
Bone: endosteal perimeter4.59.314.32.73.52.93.33.3-3.83.33.51.82.73.61.2
Bone: final force2.84.59.72.02.51.62.22.4-2.72.13.10.82.02.30.3
Bone: final moment3.15.111.22.12.51.72.52.3-2.82.13.41.12.12.40.4
Bone: marrow area1.63.57.11.61.81.82.71.4-2.31.72.11.51.62.41.1
Bone: maximum diameter8.114.922.52.73.84.14.73.9-4.74.24.33.22.74.62.3
Bone: maximum force2.74.79.32.22.61.72.22.3-2.62.13.10.92.22.30.3
Bone: maximum moment2.95.010.22.22.61.82.42.2-2.72.23.21.12.22.50.5
Bone: minimum diameter3.76.812.42.02.52.83.52.2-3.12.62.92.22.03.21.5
Bone: periosteal estimation5.611.518.33.03.53.34.33.2-4.23.53.82.43.04.11.6
Bone: periosteal perimeter9.615.925.43.34.53.94.54.4-5.04.44.62.43.34.61.6
Bone: post-yield work0.10.20.8-0.3-0.30.20.9-0.4-0.2-0.30.40.7-0.30.20.7
Bone: stiffness1.72.64.41.72.01.21.32.1-1.91.82.10.41.71.70.0
Bone: tissue strength0.20.20.4-0.7-0.6-0.1-0.1-0.60.5-0.6-0.20.3-0.7-0.40.5
Bone: trabecular number0.91.45.1-0.20.21.61.60.3-0.9-0.02.21.5-0.20.71.8
Bone: trabecular spacing0.10.10.6-0.5-0.30.0-0.30.00.30.2-0.80.1-0.5-0.2-0.2
Bone: trabecular thickness5.36.510.81.32.32.73.32.3-3.02.63.32.31.33.12.0
Bone: trabecular tissue density0.60.81.71.21.30.1-0.21.1-0.80.90.5-0.61.20.4-1.3
Breakpoint value in progressive ratio session0.50.62.3-0.8-0.50.31.1-0.3-0.2-0.20.61.5-0.80.51.1
Distance traveled before self-admin0.50.51.21.10.1-0.3-1.0-0.40.7-0.1-0.4-0.81.0-0.4-1.0
Distance traveled after self-admin0.91.02.61.60.8-0.7-0.2-0.4-0.10.11.6-0.51.60.1-1.6
Delta time in closed arm before/after self-admin0.10.10.40.3-0.0-0.6-0.6-0.10.30.1-0.2-0.30.2-0.2-0.7
Delta time in open arm before/after self-admin0.40.30.9-0.70.10.50.90.4-0.60.10.60.7-0.50.40.8
Diff in mean of infusions in LGA sessions2.02.35.3-1.3-2.3-0.6-0.7-2.22.0-1.9-1.30.0-1.5-1.70.5
Extinction: sum of active levers before priming0.80.82.5-1.6-1.1-0.6-0.1-0.80.7-0.9-0.50.9-1.5-0.40.7
Active lever presses in extinction session 60.40.31.70.00.50.40.50.4-0.50.40.91.3-0.10.60.1
Delta distance traveled before/after self-admin1.01.05.91.01.0-0.21.00.1-1.00.12.40.61.10.8-0.7
Delta ambulatory time before/after self-admin0.90.95.40.40.70.11.40.1-1.00.22.31.00.40.90.1
Time in closed arm before self-admin0.30.41.31.20.30.60.4-0.3-0.2-0.50.80.11.10.3-0.3
Time in closed arm after self-admin0.40.40.90.3-0.5-0.8-0.4-0.90.7-0.90.1-0.40.2-0.6-1.0
Time in open arm before self-admin1.31.43.4-1.0-1.5-0.9-1.1-1.41.5-0.8-1.8-0.1-1.3-1.20.0
Time in open arm after self-admin0.80.93.0-1.7-1.0-0.4-0.1-0.20.5-0.2-1.30.2-1.7-0.61.0
Sum of active levers in priming session hrs 5-61.81.83.6-1.5-1.7-0.9-1.2-1.61.6-1.9-1.2-0.2-1.4-1.40.6
Time to tail flick, vehicle, before self-admin2.22.34.00.61.51.91.52.0-1.81.91.11.20.51.81.5
Time to tail flick, vehicle, after self-admin0.30.30.80.60.70.3-0.40.9-0.30.7-0.5-0.70.7-0.0-0.5
Time to tail flick, test, before self-admin1.51.54.51.61.4-0.9-0.40.8-0.70.90.6-1.31.90.4-2.1
Time to tail flick, test, after self-admin2.32.34.41.11.61.51.71.3-1.81.72.11.31.01.90.6
Delta time to tail flick, vehicle, before/after SA0.10.10.50.2-0.0-0.2-0.5-0.20.30.1-0.5-0.50.3-0.5-0.7
Delta time to tail flick, test, before/after SA2.32.14.20.20.92.11.61.3-1.51.51.41.7-0.11.61.9
Ambulatory time before self-admin0.60.62.51.60.80.4-0.30.3-0.10.90.2-0.31.50.4-0.9
Ambulatory time after self-admin1.01.13.81.91.0-0.30.0-0.2-0.30.41.5-0.21.90.4-1.5
Total heroin consumption1.01.22.7-0.40.41.01.50.6-1.01.01.41.6-0.31.41.5
Area under the delay curve0.60.61.3-0.20.50.71.10.7-0.90.90.71.1-0.41.10.7
Delay disc. indifference point, 0s delay0.50.51.50.40.60.20.90.4-0.81.20.60.70.51.2-0.1
Delay disc. indifference point, 16s delay0.20.21.0-0.9-0.40.00.4-0.1-0.0-0.20.10.7-1.0-0.00.1
Delay disc. indifference point, 2s delay0.10.10.50.3-0.3-0.20.2-0.70.2-0.20.30.40.10.3-0.1
Delay disc. indifference point, 24s delay1.11.13.0-1.1-0.11.11.50.3-0.80.61.11.7-1.10.91.3
Delay disc. indifference point, 4s delay0.20.20.5-0.5-0.6-0.20.3-0.60.3-0.5-0.70.3-0.6-0.1-0.0
Delay disc. indifference point, 8s delay2.72.85.60.31.81.31.82.3-2.32.41.51.10.02.11.1
Delay discount exponential model param0.60.71.40.2-0.5-0.7-1.2-0.71.0-0.9-0.8-1.20.4-1.1-0.7
Delay discount hyperbolic model param0.40.41.00.0-0.3-0.5-1.0-0.40.7-0.7-0.6-1.00.3-0.9-0.5
Fecal boli incidents, locomotor time 10.80.92.9-0.80.81.20.31.7-1.01.6-0.5-0.1-0.50.60.7
Change in fecal boli incidents, locomotor task1.11.03.5-0.2-1.2-0.7-0.3-1.91.2-1.80.20.3-0.1-1.2-0.3
Time >=10cm from walls, locomotor time 11.41.43.3-0.5-1.4-0.9-1.0-1.71.5-1.8-1.4-0.4-0.7-1.30.4
Bouts of movement, locomotor time 10.91.03.1-0.80.30.71.80.7-1.20.71.41.1-0.51.10.9
Total resting periods, locomotor time 10.70.82.6-0.60.40.41.60.5-1.10.41.50.8-0.41.00.5
Rest time, locomotor task time 10.30.31.10.40.6-0.80.10.4-0.50.20.0-1.00.50.1-1.1
Distance moved, locomotor task time 10.30.31.70.2-0.00.90.20.10.0-0.30.51.30.00.20.7
Vertical activity count, locomotor time 10.40.40.90.6-0.40.2-0.9-0.91.0-0.9-0.40.20.6-0.9-0.3
Time >=10cm from walls, locomotor time 20.70.83.3-0.0-0.10.91.1-0.3-0.30.00.71.60.00.81.8
Bouts of movement, locomotor time 21.81.95.4-1.1-1.7-1.4-0.8-2.31.7-2.0-0.0-0.5-0.8-1.6-0.8
Total resting periods, locomotor time 21.21.33.6-0.8-1.3-1.2-0.5-1.91.3-1.70.3-0.3-0.6-1.2-0.9
Rest time, locomotor task time 20.20.20.80.60.50.1-0.40.4-0.20.30.5-0.40.6-0.1-0.9
Distance moved, locomotor task time 20.40.51.8-0.70.10.50.70.4-0.50.30.31.1-0.80.61.4
Vertical activity count, locomotor time 20.30.40.90.10.30.80.70.5-0.50.7-0.30.70.10.61.0
Weight adjusted by age5.35.99.82.13.11.92.03.1-3.12.73.01.02.12.80.4
Seeking ratio, delayed vs. immediate footshock0.30.41.3-0.0-0.5-1.1-0.3-0.90.5-0.50.2-0.6-0.1-0.5-0.9
Locomotion in novel chamber0.50.73.51.00.4-0.9-0.5-0.20.2-0.20.3-1.01.0-0.3-1.9
Locomotion in novel chamber post-restriction1.82.15.5-0.6-0.5-2.1-2.0-0.61.1-1.1-1.1-2.3-0.4-1.6-1.9
Progressive ratio0.60.71.7-1.1-1.0-0.9-0.9-0.40.9-0.5-1.3-0.2-1.3-0.80.1
Food seeking constrained by brief footshock0.70.82.4-1.4-1.10.10.0-1.10.7-0.60.21.2-1.6-0.50.8
Seeking ratio, punishment vs. effort0.30.31.90.30.20.60.7-0.5-0.3-0.01.40.60.40.40.1
Run reversals in cocaine runway, females0.80.81.81.21.10.30.40.9-0.90.81.3-0.31.20.7-0.5
Run reversals in cocaine runway, males1.51.54.0-0.9-1.7-0.8-0.7-2.01.6-1.6-0.80.0-1.1-1.3-0.1
Latency to leave start box in cocaine runway0.60.71.2-0.7-0.8-0.6-1.0-1.01.0-1.1-0.4-0.2-0.5-1.1-0.8
Latency to leave start box in cocaine runway, F0.80.91.6-0.2-0.8-0.5-1.2-1.31.2-1.3-0.8-0.5-0.2-1.2-0.9
Latency to leave start box in cocaine runway, M0.20.20.6-0.70.2-0.30.30.4-0.40.40.80.3-0.30.3-0.2
Cd content in liver2.62.94.8-1.8-2.0-1.4-1.3-1.91.8-2.2-1.9-1.0-1.8-2.0-0.2
Co content in liver0.40.51.90.3-0.2-0.6-0.8-0.10.5-0.7-0.6-1.40.3-0.9-0.8
Cu content in liver0.10.20.50.50.5-0.0-0.10.2-0.3-0.10.7-0.40.5-0.1-0.5
Fe content in liver0.10.10.4-0.5-0.10.0-0.00.1-0.00.2-0.6-0.2-0.50.0-0.1
K content in liver0.50.51.1-0.9-1.0-0.5-0.3-0.90.8-1.00.1-0.2-0.9-0.9-0.2
Mg content in liver0.40.41.0-1.0-0.70.00.4-0.50.2-0.80.90.6-1.0-0.30.6
Mn content in liver0.60.71.5-0.4-1.1-0.7-0.8-1.11.2-1.20.2-0.1-0.4-1.0-0.5
Na content in liver0.60.61.7-1.3-1.1-0.0-0.1-0.40.7-0.6-0.60.5-1.3-0.60.7
Rb content in liver1.72.14.8-2.2-1.9-0.9-0.6-1.61.5-1.1-1.80.3-2.2-1.10.7
Se content in liver0.20.20.6-0.8-0.60.1-0.5-0.30.5-0.50.1-0.1-0.8-0.6-0.1
Sr content in liver2.62.44.1-0.5-1.3-2.0-1.7-1.51.8-1.9-1.1-1.6-0.5-1.8-1.8
Zn content in liver2.32.65.4-0.6-1.4-1.6-2.0-1.61.9-2.3-0.1-1.4-0.6-2.2-1.8