| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000056216 | 0.1400 | 0.0690 | 9.9e-12 | 0.096 | 0.016 | 0.090 | 0.067 | 9.3e-11 | 6.3e-03 | 3.4e-10 | 6.9e-08 |
| 2 | Brain | gene expression | ENSRNOG00000056216 | 0.1300 | 0.0690 | 2.1e-14 | 0.118 | 0.169 | 0.162 | 0.159 | 4.7e-11 | 1.9e-15 | 8.0e-15 | 1.4e-14 |
| 3 | Brain | mRNA stability | ENSRNOG00000056216 | 0.1216 | 0.0822 | 6.6e-06 | 0.042 | 0.045 | 0.036 | 0.037 | 8.2e-05 | 5.0e-05 | 2.8e-04 | 2.0e-04 |
| 4 | Eye | gene expression | ENSRNOG00000056216 | 0.5100 | 0.2300 | 3.9e-03 | 0.049 | 0.118 | 0.013 | 0.047 | 6.2e-02 | 7.2e-03 | 2.0e-01 | 6.7e-02 |
| 5 | LHb | gene expression | ENSRNOG00000056216 | 0.1231 | 0.0903 | 9.4e-03 | 0.115 | 0.080 | 0.078 | 0.096 | 1.1e-03 | 6.0e-03 | 6.5e-03 | 2.8e-03 |
| 6 | Liver | alternative TSS | ENSRNOT00000080511 | 0.0222 | 0.0152 | 3.4e-03 | 0.014 | 0.014 | 0.001 | 0.010 | 8.9e-03 | 8.5e-03 | 2.6e-01 | 2.3e-02 |
| 7 | Liver | alternative TSS | ENSRNOT00000103804 | 0.0215 | 0.0149 | 4.2e-03 | 0.013 | 0.013 | -0.001 | 0.007 | 1.3e-02 | 1.3e-02 | 4.9e-01 | 4.5e-02 |
| 8 | NAcc | gene expression | ENSRNOG00000056216 | 0.2100 | 0.1100 | 1.4e-09 | 0.102 | 0.100 | 0.119 | 0.102 | 5.4e-08 | 7.3e-08 | 3.5e-09 | 4.8e-08 |
| 9 | NAcc | mRNA stability | ENSRNOG00000056216 | 0.0692 | 0.0501 | 9.2e-04 | 0.039 | 0.040 | 0.051 | 0.035 | 6.2e-04 | 5.4e-04 | 1.1e-04 | 1.2e-03 |
| 10 | OFC | gene expression | ENSRNOG00000056216 | 0.1844 | 0.1389 | 8.8e-03 | 0.020 | 0.015 | 0.002 | -0.006 | 1.1e-01 | 1.4e-01 | 2.9e-01 | 4.8e-01 |
| 11 | PL | gene expression | ENSRNOG00000056216 | 0.1189 | 0.0616 | 2.6e-08 | 0.097 | 0.101 | 0.104 | 0.102 | 7.8e-08 | 4.0e-08 | 2.6e-08 | 3.7e-08 |
| 12 | PL | mRNA stability | ENSRNOG00000056216 | 0.0897 | 0.0519 | 4.7e-05 | 0.071 | 0.059 | 0.071 | 0.062 | 4.2e-06 | 2.9e-05 | 4.6e-06 | 1.9e-05 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Epididymis fat weight | 13.9 | 32.4 | 50.1 | 4.8 | 5.7 | 5.6 | 6.7 | 5.3 | -6.7 | 5.9 | 7.1 | 4.7 | 4.5 | 7.1 | 2.7 |
| Retroperitoneal fat weight | 12.2 | 40.4 | 62.8 | 5.6 | 6.6 | 6.3 | 7.3 | 6.0 | -7.4 | 6.4 | 7.9 | 4.8 | 5.6 | 7.8 | 2.8 |
| Bone: periosteal perimeter | 9.6 | 15.9 | 25.4 | 3.3 | 4.5 | 3.9 | 4.5 | 4.4 | -5.0 | 4.4 | 4.6 | 2.4 | 3.3 | 4.6 | 1.6 |
| Body weight | 9.3 | 39.3 | 65.5 | 6.1 | 6.7 | 6.1 | 7.1 | 5.8 | -7.2 | 5.9 | 8.1 | 4.5 | 6.1 | 7.4 | 2.1 |
| Bone: cortical area | 9.2 | 13.9 | 21.5 | 2.9 | 4.0 | 3.8 | 4.4 | 3.9 | -4.6 | 4.0 | 4.4 | 2.6 | 2.9 | 4.3 | 1.6 |
| BMI with tail | 8.1 | 26.2 | 39.2 | 5.0 | 5.6 | 5.1 | 5.8 | 5.0 | -6.1 | 4.8 | 6.3 | 3.4 | 5.0 | 5.9 | 1.5 |
| Parametrial fat weight | 8.1 | 15.9 | 26.6 | 2.0 | 3.5 | 4.5 | 5.2 | 3.8 | -4.7 | 4.0 | 4.5 | 3.8 | 2.0 | 5.0 | 3.3 |
| Bone: maximum diameter | 8.1 | 14.9 | 22.5 | 2.7 | 3.8 | 4.1 | 4.7 | 3.9 | -4.7 | 4.2 | 4.3 | 3.2 | 2.7 | 4.6 | 2.3 |
| Liver weight, right | 7.0 | 11.7 | 18.1 | 3.1 | 3.7 | 3.2 | 4.0 | 3.3 | -4.1 | 3.4 | 4.0 | 2.4 | 3.2 | 4.3 | 1.2 |
| Baseline Anxiety | 5.8 | 6.1 | 9.8 | 0.8 | 2.5 | 2.6 | 2.9 | 2.7 | -3.1 | 2.7 | 2.8 | 2.4 | 1.0 | 3.0 | 1.7 |
| Bone: periosteal estimation | 5.6 | 11.5 | 18.3 | 3.0 | 3.5 | 3.3 | 4.3 | 3.2 | -4.2 | 3.5 | 3.8 | 2.4 | 3.0 | 4.1 | 1.6 |
| Bone: trabecular thickness | 5.3 | 6.5 | 10.8 | 1.3 | 2.3 | 2.7 | 3.3 | 2.3 | -3.0 | 2.6 | 3.3 | 2.3 | 1.3 | 3.1 | 2.0 |
| Weight adjusted by age | 5.3 | 5.9 | 9.8 | 2.1 | 3.1 | 1.9 | 2.0 | 3.1 | -3.1 | 2.7 | 3.0 | 1.0 | 2.1 | 2.8 | 0.4 |
| Length without tail | 5.2 | 11.3 | 17.6 | 3.3 | 3.8 | 3.0 | 3.3 | 3.7 | -3.8 | 3.7 | 4.2 | 1.9 | 3.4 | 3.8 | 1.1 |
| Glucose | 5.0 | 7.7 | 11.3 | 2.8 | 3.1 | 3.1 | 2.4 | 2.7 | -2.9 | 3.4 | 3.0 | 1.9 | 2.8 | 3.2 | 0.8 |
| Right kidney weight | 4.7 | 13.3 | 25.5 | 5.1 | 4.7 | 1.6 | 2.6 | 3.5 | -4.0 | 3.4 | 4.6 | 0.2 | 4.9 | 3.9 | -1.5 |
| Bone: cortical thickness | 4.6 | 7.6 | 11.4 | 2.5 | 3.2 | 2.5 | 2.8 | 3.1 | -3.4 | 3.2 | 3.2 | 1.6 | 2.5 | 3.1 | 0.6 |
| Bone: endosteal perimeter | 4.5 | 9.3 | 14.3 | 2.7 | 3.5 | 2.9 | 3.3 | 3.3 | -3.8 | 3.3 | 3.5 | 1.8 | 2.7 | 3.6 | 1.2 |
| Cocaine induced anxiety | 4.4 | 5.1 | 8.4 | -0.2 | -2.2 | -2.3 | -2.5 | -2.9 | 2.9 | -2.7 | -2.3 | -2.0 | -0.4 | -2.8 | -2.0 |
| Delay discounting total patch changes 6 sec | 4.2 | 6.4 | 10.2 | 0.8 | 2.3 | 2.7 | 3.2 | 2.8 | -3.2 | 3.0 | 2.4 | 2.3 | 0.8 | 3.1 | 2.2 |
| Social responses | 4.1 | 5.3 | 8.9 | 1.6 | 2.7 | 1.8 | 2.4 | 2.8 | -3.0 | 2.6 | 2.5 | 1.6 | 1.5 | 2.9 | 1.1 |
| Liver weight, left | 3.9 | 6.3 | 10.1 | 1.4 | 2.4 | 2.6 | 3.2 | 2.4 | -3.1 | 2.3 | 3.0 | 2.4 | 1.4 | 3.2 | 1.8 |
| Bone: minimum diameter | 3.7 | 6.8 | 12.4 | 2.0 | 2.5 | 2.8 | 3.5 | 2.2 | -3.1 | 2.6 | 2.9 | 2.2 | 2.0 | 3.2 | 1.5 |
| Total sessions with >9 infusions | 3.6 | 3.9 | 8.7 | 1.7 | 2.8 | 0.1 | 1.0 | 3.0 | -2.5 | 2.9 | 1.8 | -0.3 | 1.7 | 2.1 | -0.9 |
| BMI without tail | 3.5 | 7.3 | 11.8 | 2.6 | 2.9 | 2.8 | 3.4 | 2.2 | -3.3 | 2.0 | 3.3 | 2.1 | 2.5 | 3.3 | 0.7 |
| Soleus weight | 3.5 | 10.3 | 19.4 | 3.7 | 3.7 | 2.3 | 2.8 | 2.9 | -3.5 | 3.7 | 4.4 | 1.5 | 3.7 | 3.7 | -0.0 |
| Intermittent access intake escalation | 3.5 | 3.5 | 6.4 | 1.8 | 2.4 | 1.3 | 1.3 | 2.2 | -2.1 | 2.5 | 1.9 | 0.9 | 2.0 | 2.2 | 0.3 |
| Indifference point 0 sec | 3.4 | 5.5 | 8.1 | 1.2 | 2.3 | 2.6 | 2.7 | 2.4 | -2.8 | 2.8 | 2.7 | 1.9 | 1.3 | 2.8 | 1.7 |
| Delay discounting total patch changes 0 sec | 3.4 | 5.5 | 8.1 | 1.0 | 2.1 | 2.7 | 2.8 | 2.4 | -2.8 | 2.8 | 2.6 | 2.0 | 1.1 | 2.8 | 1.8 |
| Intraocular pressure | 3.3 | 4.6 | 8.5 | 0.6 | 2.2 | 2.2 | 2.6 | 2.9 | -2.9 | 2.6 | 1.5 | 1.6 | 0.5 | 2.6 | 2.0 |
| Left kidney weight | 3.2 | 9.1 | 23.7 | 4.9 | 3.7 | 0.2 | 1.8 | 2.1 | -2.8 | 2.3 | 3.8 | -0.2 | 4.8 | 2.9 | -2.1 |
| Cocaine response after cond. not corrected | 3.1 | 3.4 | 6.4 | -0.9 | -1.4 | -2.3 | -2.4 | -1.3 | 1.9 | -1.7 | -2.5 | -2.1 | -0.9 | -2.1 | -1.6 |
| Bone volume | 3.1 | 5.2 | 15.4 | 1.5 | 1.9 | 2.5 | 2.9 | 1.7 | -2.5 | 1.6 | 3.9 | 2.1 | 1.5 | 2.4 | 1.7 |
| Bone: final moment | 3.1 | 5.1 | 11.2 | 2.1 | 2.5 | 1.7 | 2.5 | 2.3 | -2.8 | 2.1 | 3.4 | 1.1 | 2.1 | 2.4 | 0.4 |
| Cocaine response after cond. corrected | 2.9 | 3.2 | 6.6 | -0.5 | -1.0 | -2.6 | -2.3 | -1.1 | 1.7 | -1.4 | -2.3 | -2.4 | -0.5 | -1.9 | -2.1 |
| Condit. Reinf. active responses | 2.9 | 4.1 | 9.0 | -0.8 | 1.4 | 2.5 | 2.1 | 2.7 | -2.4 | 2.2 | 0.7 | 2.0 | -0.8 | 1.9 | 3.0 |
| Intermittent access intake day 1-15 change | 2.9 | 2.9 | 5.6 | 1.1 | 1.8 | 1.8 | 1.5 | 2.0 | -1.9 | 2.4 | 1.5 | 1.5 | 1.2 | 2.0 | 1.3 |
| Bone: maximum moment | 2.9 | 5.0 | 10.2 | 2.2 | 2.6 | 1.8 | 2.4 | 2.2 | -2.7 | 2.2 | 3.2 | 1.1 | 2.2 | 2.5 | 0.5 |
| Bone: final force | 2.8 | 4.5 | 9.7 | 2.0 | 2.5 | 1.6 | 2.2 | 2.4 | -2.7 | 2.1 | 3.1 | 0.8 | 2.0 | 2.3 | 0.3 |
| Bone: maximum force | 2.7 | 4.7 | 9.3 | 2.2 | 2.6 | 1.7 | 2.2 | 2.3 | -2.6 | 2.1 | 3.1 | 0.9 | 2.2 | 2.3 | 0.3 |
| Delay disc. indifference point, 8s delay | 2.7 | 2.8 | 5.6 | 0.3 | 1.8 | 1.3 | 1.8 | 2.3 | -2.3 | 2.4 | 1.5 | 1.1 | 0.0 | 2.1 | 1.1 |
| Social response proportion | 2.6 | 2.9 | 7.3 | 2.7 | 2.2 | 0.3 | 0.7 | 1.4 | -1.6 | 1.3 | 2.4 | -0.2 | 2.6 | 1.3 | -1.1 |
| Cd content in liver | 2.6 | 2.9 | 4.8 | -1.8 | -2.0 | -1.4 | -1.3 | -1.9 | 1.8 | -2.2 | -1.9 | -1.0 | -1.8 | -2.0 | -0.2 |
| Sr content in liver | 2.6 | 2.4 | 4.1 | -0.5 | -1.3 | -2.0 | -1.7 | -1.5 | 1.8 | -1.9 | -1.1 | -1.6 | -0.5 | -1.8 | -1.8 |
| Heart weight | 2.5 | 3.6 | 5.7 | 1.8 | 2.3 | 1.5 | 1.9 | 2.2 | -2.4 | 2.2 | 2.0 | 1.0 | 1.7 | 2.3 | 0.6 |
| Delay discounting total patch changes 18 sec | 2.4 | 3.1 | 6.8 | -0.4 | 1.2 | 1.8 | 2.6 | 1.7 | -2.3 | 1.9 | 1.0 | 1.9 | -0.4 | 2.1 | 2.2 |
| Bone: cortical thickness | 2.4 | 2.8 | 5.6 | 2.1 | 2.0 | 1.2 | 1.4 | 1.5 | -1.8 | 1.7 | 2.4 | 0.7 | 2.1 | 1.8 | -0.1 |
| Length with tail | 2.3 | 8.4 | 15.3 | 2.7 | 3.1 | 2.5 | 3.2 | 2.6 | -3.3 | 2.9 | 3.9 | 2.2 | 2.7 | 3.7 | 1.0 |
| Time to tail flick, test, after self-admin | 2.3 | 2.3 | 4.4 | 1.1 | 1.6 | 1.5 | 1.7 | 1.3 | -1.8 | 1.7 | 2.1 | 1.3 | 1.0 | 1.9 | 0.6 |
| Delta time to tail flick, test, before/after SA | 2.3 | 2.1 | 4.2 | 0.2 | 0.9 | 2.1 | 1.6 | 1.3 | -1.5 | 1.5 | 1.4 | 1.7 | -0.1 | 1.6 | 1.9 |
| Zn content in liver | 2.3 | 2.6 | 5.4 | -0.6 | -1.4 | -1.6 | -2.0 | -1.6 | 1.9 | -2.3 | -0.1 | -1.4 | -0.6 | -2.2 | -1.8 |
| Light reinforcement 2 | 2.2 | 2.9 | 5.6 | -1.0 | -1.8 | -2.1 | -1.4 | -2.2 | 2.0 | -2.4 | -1.5 | -1.2 | -1.0 | -1.7 | -1.4 |
| Bone: apparent density | 2.2 | 3.7 | 11.6 | 0.6 | 1.2 | 2.3 | 2.6 | 1.3 | -2.0 | 1.0 | 3.4 | 2.1 | 0.6 | 1.8 | 2.1 |
| Time to tail flick, vehicle, before self-admin | 2.2 | 2.3 | 4.0 | 0.6 | 1.5 | 1.9 | 1.5 | 2.0 | -1.8 | 1.9 | 1.1 | 1.2 | 0.5 | 1.8 | 1.5 |
| Delay discounting total patch changes 24 sec | 2.1 | 2.6 | 5.7 | -0.7 | 0.7 | 1.6 | 2.4 | 1.2 | -1.8 | 1.6 | 1.4 | 2.1 | -0.7 | 1.8 | 2.2 |
| Condit. Reinf. lever reinforcers received | 2.1 | 2.9 | 7.0 | -0.9 | 1.1 | 1.9 | 1.8 | 2.3 | -2.0 | 1.8 | 0.4 | 1.7 | -0.9 | 1.6 | 2.6 |
| Intermittent access day 15 total locomotion | 2.1 | 2.2 | 4.5 | 0.6 | 1.8 | 1.3 | 1.3 | 2.1 | -1.9 | 2.0 | 1.7 | 0.9 | 0.8 | 1.8 | 0.6 |
| One hour access (0.3 mA shock) | 2.0 | 2.3 | 4.4 | -0.5 | 1.0 | 1.0 | 1.7 | 1.5 | -1.6 | 1.6 | 2.1 | 2.0 | -0.5 | 1.9 | 1.7 |
| Time in familiar zone, hab. session 2 | 2.0 | 2.1 | 6.1 | -0.1 | 0.7 | 1.6 | 2.0 | 1.2 | -1.5 | 0.9 | 1.3 | 1.9 | -0.0 | 1.5 | 2.5 |
| Diff in mean of infusions in LGA sessions | 2.0 | 2.3 | 5.3 | -1.3 | -2.3 | -0.6 | -0.7 | -2.2 | 2.0 | -1.9 | -1.3 | 0.0 | -1.5 | -1.7 | 0.5 |
| Intermitt. access day 1 inactive lever presses | 1.9 | 2.0 | 4.2 | 0.3 | 1.0 | 1.8 | 2.0 | 1.1 | -1.6 | 1.2 | 1.9 | 1.6 | 0.4 | 1.7 | 1.2 |
| Locomotor testing distance | 1.8 | 2.9 | 5.6 | 2.3 | 2.3 | 0.9 | 0.4 | 2.2 | -1.6 | 2.1 | 1.5 | -0.1 | 2.4 | 1.6 | -0.9 |
| Condit. Reinf. inactive responses | 1.8 | 2.3 | 4.1 | -0.1 | 1.1 | 1.9 | 1.4 | 1.9 | -1.6 | 1.9 | 0.7 | 1.9 | -0.1 | 1.6 | 2.0 |
| Intermittent access intake escalation 2 | 1.8 | 1.8 | 3.3 | 1.7 | 1.7 | 0.5 | 0.7 | 1.5 | -1.4 | 1.8 | 1.3 | 0.4 | 1.7 | 1.6 | -0.2 |
| Bone: cortical tissue density | 1.8 | 2.4 | 7.9 | 1.0 | 0.3 | -1.7 | -2.5 | -0.3 | 1.1 | -0.4 | -0.7 | -2.3 | 1.0 | -1.4 | -2.8 |
| Sum of active levers in priming session hrs 5-6 | 1.8 | 1.8 | 3.6 | -1.5 | -1.7 | -0.9 | -1.2 | -1.6 | 1.6 | -1.9 | -1.2 | -0.2 | -1.4 | -1.4 | 0.6 |
| Bouts of movement, locomotor time 2 | 1.8 | 1.9 | 5.4 | -1.1 | -1.7 | -1.4 | -0.8 | -2.3 | 1.7 | -2.0 | -0.0 | -0.5 | -0.8 | -1.6 | -0.8 |
| Locomotion in novel chamber post-restriction | 1.8 | 2.1 | 5.5 | -0.6 | -0.5 | -2.1 | -2.0 | -0.6 | 1.1 | -1.1 | -1.1 | -2.3 | -0.4 | -1.6 | -1.9 |
| Tibia length | 1.7 | 4.7 | 9.3 | 3.0 | 2.7 | 1.4 | 1.8 | 2.0 | -2.4 | 2.1 | 2.3 | 0.3 | 3.0 | 2.4 | -0.2 |
| Progressive ratio test 2 active lever presses | 1.7 | 1.8 | 3.7 | 0.6 | 1.8 | 0.0 | 0.9 | 1.9 | -1.8 | 1.9 | 1.9 | 0.5 | 0.6 | 1.6 | -0.1 |
| Locomotion velocity, session 8 | 1.7 | 2.1 | 4.5 | -0.5 | -1.6 | -1.2 | -1.3 | -1.9 | 1.8 | -2.1 | -1.6 | -0.8 | -0.6 | -1.8 | -0.9 |
| Bone: cortical apparent density | 1.7 | 2.2 | 7.8 | 1.2 | 0.5 | -1.6 | -2.3 | -0.1 | 0.8 | -0.2 | -0.5 | -2.3 | 1.2 | -1.2 | -2.8 |
| Bone: stiffness | 1.7 | 2.6 | 4.4 | 1.7 | 2.0 | 1.2 | 1.3 | 2.1 | -1.9 | 1.8 | 2.1 | 0.4 | 1.7 | 1.7 | 0.0 |
| Rb content in liver | 1.7 | 2.1 | 4.8 | -2.2 | -1.9 | -0.9 | -0.6 | -1.6 | 1.5 | -1.1 | -1.8 | 0.3 | -2.2 | -1.1 | 0.7 |
| Condit. Reinf. active minus inactive responses | 1.6 | 1.9 | 5.7 | -1.2 | 0.7 | 1.6 | 1.3 | 1.9 | -1.6 | 1.3 | -0.0 | 1.1 | -1.2 | 1.0 | 2.4 |
| Bone: marrow area | 1.6 | 3.5 | 7.1 | 1.6 | 1.8 | 1.8 | 2.7 | 1.4 | -2.3 | 1.7 | 2.1 | 1.5 | 1.6 | 2.4 | 1.1 |
| Intermittent access standard deviation | 1.5 | 1.6 | 4.1 | -0.6 | 0.4 | 0.8 | 1.6 | 0.9 | -1.2 | 1.3 | 1.3 | 1.8 | -0.6 | 1.5 | 2.0 |
| Bone: endosteal estimation | 1.5 | 3.3 | 6.7 | 1.5 | 1.7 | 1.7 | 2.6 | 1.4 | -2.2 | 1.7 | 2.1 | 1.4 | 1.5 | 2.3 | 1.1 |
| Time to tail flick, test, before self-admin | 1.5 | 1.5 | 4.5 | 1.6 | 1.4 | -0.9 | -0.4 | 0.8 | -0.7 | 0.9 | 0.6 | -1.3 | 1.9 | 0.4 | -2.1 |
| Run reversals in cocaine runway, males | 1.5 | 1.5 | 4.0 | -0.9 | -1.7 | -0.8 | -0.7 | -2.0 | 1.6 | -1.6 | -0.8 | 0.0 | -1.1 | -1.3 | -0.1 |
| Locomotor activity | 1.4 | 2.3 | 4.6 | 1.6 | 1.9 | 1.3 | 0.8 | 1.7 | -1.5 | 1.7 | 2.2 | 0.7 | 1.8 | 1.7 | -0.2 |
| Social time | 1.4 | 1.9 | 3.8 | 1.6 | 1.8 | 0.6 | 0.9 | 1.5 | -1.5 | 1.5 | 1.9 | 0.5 | 1.4 | 1.6 | -0.3 |
| Pavlov. Cond. magazine entry latency | 1.4 | 1.6 | 3.5 | 0.4 | 0.8 | 1.1 | 1.8 | 0.7 | -1.3 | 1.2 | 1.9 | 1.8 | 0.4 | 1.6 | 0.9 |
| Incentive Sensitization - Breakpoint | 1.4 | 1.4 | 2.6 | 0.4 | 1.4 | 1.0 | 1.1 | 1.6 | -1.5 | 1.6 | 1.4 | 0.9 | 0.5 | 1.4 | 0.7 |
| Progressive ratio test 2 breakpoint | 1.4 | 1.6 | 3.4 | 0.4 | 1.6 | 0.0 | 0.9 | 1.8 | -1.7 | 1.8 | 1.7 | 0.5 | 0.4 | 1.6 | -0.0 |
| One hour access (shock baseline) | 1.4 | 1.7 | 3.9 | 0.7 | 1.6 | 0.4 | 1.0 | 1.8 | -1.6 | 1.8 | 2.0 | 0.6 | 0.6 | 1.6 | 0.2 |
| Time >=10cm from walls, locomotor time 1 | 1.4 | 1.4 | 3.3 | -0.5 | -1.4 | -0.9 | -1.0 | -1.7 | 1.5 | -1.8 | -1.4 | -0.4 | -0.7 | -1.3 | 0.4 |
| Pavlov. Cond. index score | 1.3 | 1.7 | 3.6 | -0.2 | 0.9 | 1.1 | 1.9 | 1.2 | -1.6 | 1.4 | 1.2 | 1.6 | -0.2 | 1.6 | 1.2 |
| Pavlov. Cond. latency score | 1.3 | 1.6 | 3.7 | -0.2 | 0.8 | 1.1 | 1.9 | 1.1 | -1.6 | 1.3 | 1.3 | 1.7 | -0.2 | 1.6 | 1.3 |
| Incentive Sensitization - Responses | 1.3 | 1.3 | 2.4 | 0.5 | 1.3 | 0.8 | 1.0 | 1.5 | -1.4 | 1.5 | 1.5 | 0.8 | 0.6 | 1.4 | 0.5 |
| Total zone transitions, hab. session 2 | 1.3 | 1.7 | 2.9 | 1.5 | 1.7 | 0.4 | 1.1 | 1.5 | -1.6 | 1.4 | 1.4 | 0.0 | 1.5 | 1.3 | -0.9 |
| Time in open arm before self-admin | 1.3 | 1.4 | 3.4 | -1.0 | -1.5 | -0.9 | -1.1 | -1.4 | 1.5 | -0.8 | -1.8 | -0.1 | -1.3 | -1.2 | 0.0 |
| Delay discounting water rate 12 sec | 1.2 | 1.7 | 4.9 | 0.4 | 0.9 | 2.2 | 1.7 | 1.2 | -1.4 | 1.4 | 0.8 | 1.1 | 0.4 | 1.3 | 1.6 |
| Delay discounting water rate 24 sec | 1.2 | 1.7 | 2.8 | 1.7 | 1.5 | 0.6 | 1.4 | 1.1 | -1.5 | 1.2 | 1.6 | 0.2 | 1.6 | 1.5 | -0.4 |
| Light reinforcement 1 | 1.2 | 2.3 | 4.7 | -1.2 | -1.7 | -1.7 | -1.2 | -2.2 | 1.8 | -2.0 | -1.4 | -0.7 | -1.1 | -1.6 | -0.7 |
| Std. dev. reaction times | 1.2 | 1.7 | 4.7 | 0.6 | 1.9 | 0.7 | 0.8 | 2.2 | -1.8 | 1.8 | 0.8 | 0.5 | 0.8 | 1.6 | 0.2 |
| Pavlov. Cond. magazine entry number | 1.2 | 1.5 | 3.2 | -0.4 | -0.8 | -1.1 | -1.7 | -0.7 | 1.3 | -1.1 | -1.8 | -1.7 | -0.3 | -1.5 | -0.9 |
| Pavlov. Cond. lever-magazine prob. diff. | 1.2 | 1.5 | 3.0 | -0.1 | 1.0 | 0.9 | 1.7 | 1.3 | -1.6 | 1.4 | 1.1 | 1.4 | -0.1 | 1.6 | 1.0 |
| Progressive ratio test 2 inactive lever presses | 1.2 | 1.3 | 3.2 | 0.2 | 1.0 | 0.9 | 1.2 | 1.2 | -1.3 | 1.3 | 1.8 | 1.2 | 0.3 | 1.4 | 1.2 |
| Total zone transitions, hab. session 1 | 1.2 | 1.6 | 2.7 | 1.6 | 1.6 | 0.3 | 0.9 | 1.4 | -1.5 | 1.5 | 1.3 | -0.0 | 1.6 | 1.4 | -0.7 |
| Total resting periods, locomotor time 2 | 1.2 | 1.3 | 3.6 | -0.8 | -1.3 | -1.2 | -0.5 | -1.9 | 1.3 | -1.7 | 0.3 | -0.3 | -0.6 | -1.2 | -0.9 |
| Delay discounting total patch changes 12 sec | 1.1 | 1.5 | 4.0 | -0.3 | 0.5 | 1.4 | 2.0 | 0.8 | -1.3 | 1.0 | 1.2 | 1.6 | -0.4 | 1.4 | 1.6 |
| Reaction time premature initiations | 1.1 | 1.6 | 3.3 | 1.6 | 1.7 | 0.3 | 0.7 | 1.2 | -1.4 | 1.8 | 1.1 | -0.2 | 1.7 | 1.3 | -0.6 |
| Locomotion velocity, session 1 | 1.1 | 1.2 | 3.0 | -1.4 | -0.8 | -1.1 | -1.2 | -0.1 | 0.7 | -0.6 | -1.7 | -1.3 | -1.4 | -1.1 | -0.4 |
| Time in novel zone, hab. session 2 | 1.1 | 1.1 | 4.3 | 0.5 | 0.0 | -1.1 | -1.4 | -0.4 | 0.7 | -0.2 | -0.6 | -1.7 | 0.5 | -0.8 | -2.1 |
| Bone: elastic work | 1.1 | 1.4 | 3.2 | 1.8 | 1.5 | 0.5 | 0.8 | 0.9 | -1.2 | 1.1 | 1.5 | -0.0 | 1.8 | 1.0 | -0.8 |
| Delay disc. indifference point, 24s delay | 1.1 | 1.1 | 3.0 | -1.1 | -0.1 | 1.1 | 1.5 | 0.3 | -0.8 | 0.6 | 1.1 | 1.7 | -1.1 | 0.9 | 1.3 |
| Change in fecal boli incidents, locomotor task | 1.1 | 1.0 | 3.5 | -0.2 | -1.2 | -0.7 | -0.3 | -1.9 | 1.2 | -1.8 | 0.2 | 0.3 | -0.1 | -1.2 | -0.3 |
| Locomotor testing rearing | 1.0 | 1.6 | 3.1 | 1.6 | 1.6 | 0.9 | 0.6 | 1.6 | -1.2 | 1.5 | 1.4 | 0.4 | 1.8 | 1.2 | -0.6 |
| Pavlov. Cond. change in total contacts | 1.0 | 1.4 | 3.0 | -0.7 | 0.6 | 1.0 | 1.6 | 1.3 | -1.4 | 1.2 | 0.5 | 1.4 | -0.8 | 1.3 | 1.7 |
| Pavlov. Cond. response bias | 1.0 | 1.3 | 3.0 | -0.2 | 0.7 | 1.0 | 1.7 | 0.9 | -1.4 | 1.4 | 0.7 | 1.6 | -0.2 | 1.5 | 1.3 |
| Intermittent access day 15 total infusions | 1.0 | 1.2 | 3.2 | 0.2 | 1.2 | 0.0 | 0.9 | 1.2 | -1.3 | 1.5 | 1.8 | 0.9 | 0.4 | 1.4 | 0.2 |
| Post-drug Anxiety | 1.0 | 1.1 | 2.1 | 0.4 | -0.9 | -1.2 | -1.0 | -1.4 | 1.2 | -1.2 | -0.9 | -0.9 | 0.1 | -1.2 | -1.4 |
| Locomotion velocity, session 2 | 1.0 | 1.2 | 4.8 | 0.8 | 0.4 | -1.1 | -1.5 | -0.0 | 0.5 | -0.1 | -0.4 | -1.8 | 0.9 | -0.8 | -2.2 |
| Degree of sensitization distance | 1.0 | 1.0 | 2.3 | -1.1 | -1.4 | 0.3 | 0.6 | -1.1 | 0.7 | -0.8 | -0.7 | 1.2 | -1.2 | -0.1 | 1.5 |
| Pavlov. Cond. magazine entry number | 1.0 | 1.2 | 2.0 | -1.4 | -1.4 | -0.7 | -0.9 | -1.1 | 1.2 | -1.4 | -1.2 | -0.5 | -1.4 | -1.2 | 0.2 |
| Delta distance traveled before/after self-admin | 1.0 | 1.0 | 5.9 | 1.0 | 1.0 | -0.2 | 1.0 | 0.1 | -1.0 | 0.1 | 2.4 | 0.6 | 1.1 | 0.8 | -0.7 |
| Ambulatory time after self-admin | 1.0 | 1.1 | 3.8 | 1.9 | 1.0 | -0.3 | 0.0 | -0.2 | -0.3 | 0.4 | 1.5 | -0.2 | 1.9 | 0.4 | -1.5 |
| Total heroin consumption | 1.0 | 1.2 | 2.7 | -0.4 | 0.4 | 1.0 | 1.5 | 0.6 | -1.0 | 1.0 | 1.4 | 1.6 | -0.3 | 1.4 | 1.5 |
| Reaction time trials AUC | 0.9 | 1.2 | 2.3 | 0.7 | 0.9 | 1.3 | 1.5 | 1.1 | -1.3 | 1.2 | 1.1 | 1.0 | 0.5 | 1.3 | 0.9 |
| Conditioned locomotion | 0.9 | 1.1 | 4.7 | -0.6 | -0.3 | -2.2 | -1.3 | -0.4 | 0.6 | -0.5 | -0.3 | -1.6 | -0.6 | -0.9 | -1.4 |
| Short access total locomotion | 0.9 | 0.9 | 3.1 | 0.9 | 1.0 | -1.2 | -0.3 | 0.7 | -0.6 | 0.8 | 0.5 | -1.3 | 1.0 | 0.3 | -1.8 |
| Time in novel zone, hab. session 1 | 0.9 | 0.9 | 2.5 | -0.0 | 0.3 | 0.9 | 1.6 | 0.3 | -0.9 | 0.9 | 0.7 | 1.6 | -0.0 | 1.3 | 1.1 |
| Bone surface | 0.9 | 1.6 | 4.9 | 0.9 | 0.9 | 1.5 | 1.8 | 0.6 | -1.3 | 0.6 | 2.2 | 1.2 | 0.9 | 1.2 | 1.1 |
| Bone: trabecular number | 0.9 | 1.4 | 5.1 | -0.2 | 0.2 | 1.6 | 1.6 | 0.3 | -0.9 | -0.0 | 2.2 | 1.5 | -0.2 | 0.7 | 1.8 |
| Distance traveled after self-admin | 0.9 | 1.0 | 2.6 | 1.6 | 0.8 | -0.7 | -0.2 | -0.4 | -0.1 | 0.1 | 1.6 | -0.5 | 1.6 | 0.1 | -1.6 |
| Delta ambulatory time before/after self-admin | 0.9 | 0.9 | 5.4 | 0.4 | 0.7 | 0.1 | 1.4 | 0.1 | -1.0 | 0.2 | 2.3 | 1.0 | 0.4 | 0.9 | 0.1 |
| Bouts of movement, locomotor time 1 | 0.9 | 1.0 | 3.1 | -0.8 | 0.3 | 0.7 | 1.8 | 0.7 | -1.2 | 0.7 | 1.4 | 1.1 | -0.5 | 1.1 | 0.9 |
| Number of licking bursts | 0.8 | 1.0 | 2.7 | -0.1 | 0.3 | 1.0 | 1.5 | 0.4 | -0.9 | 0.7 | 1.3 | 1.6 | -0.2 | 1.1 | 1.1 |
| Reaction time number correct | 0.8 | 1.1 | 2.1 | 0.7 | 0.8 | 1.3 | 1.5 | 0.9 | -1.2 | 1.1 | 1.1 | 1.0 | 0.5 | 1.2 | 0.9 |
| Reaction time trials correct on left | 0.8 | 1.1 | 2.1 | 0.7 | 0.8 | 1.3 | 1.5 | 0.9 | -1.2 | 1.1 | 1.1 | 1.0 | 0.5 | 1.2 | 0.9 |
| Reaction time trials on left | 0.8 | 1.2 | 2.3 | 0.7 | 0.9 | 1.3 | 1.5 | 1.0 | -1.3 | 1.1 | 1.1 | 1.1 | 0.5 | 1.3 | 0.9 |
| Reaction time trials completed | 0.8 | 1.2 | 2.3 | 0.7 | 0.9 | 1.3 | 1.5 | 1.0 | -1.3 | 1.1 | 1.1 | 1.1 | 0.5 | 1.3 | 0.9 |
| Conditioned reinforcement - actives | 0.8 | 0.8 | 4.2 | -0.6 | -0.1 | -2.0 | -1.0 | -0.0 | 0.3 | 0.0 | -0.3 | -1.4 | -0.6 | -0.5 | -1.3 |
| Short access day 10 total locomotion | 0.8 | 0.9 | 2.8 | 1.5 | 1.1 | 0.4 | 0.3 | 0.7 | -0.7 | 0.9 | 0.4 | -0.3 | 1.7 | 0.7 | -1.1 |
| Locomotion distance, session 1 | 0.8 | 1.0 | 3.3 | 0.2 | 0.5 | -1.2 | -1.4 | 0.6 | 0.1 | -0.2 | -0.8 | -1.8 | 0.2 | -0.8 | -1.8 |
| Locomotion distance, session 2 | 0.8 | 1.1 | 2.1 | 1.3 | 1.5 | -0.6 | 0.6 | 1.2 | -1.3 | 1.1 | 0.7 | -0.7 | 1.2 | 1.0 | -1.2 |
| Locomotion distance, session 3 | 0.8 | 0.8 | 3.7 | 1.2 | 0.7 | -0.9 | -0.9 | 0.1 | 0.1 | 0.1 | 0.0 | -1.2 | 1.2 | -0.3 | -1.9 |
| Locomotion distance, session 8 | 0.8 | 1.2 | 3.6 | 0.8 | -0.5 | -1.3 | -0.9 | -1.3 | 1.0 | -1.2 | -0.8 | -1.1 | 0.7 | -0.9 | -1.9 |
| Condit. Reinf. inactive responses | 0.8 | 0.9 | 2.7 | -0.1 | 1.0 | 0.8 | 0.9 | 1.6 | -1.4 | 1.6 | -0.2 | 0.2 | -0.1 | 1.1 | 0.8 |
| Bone: cortical porosity | 0.8 | 0.8 | 2.4 | -0.3 | -0.1 | 0.8 | 1.4 | -0.2 | -0.6 | -0.0 | 1.3 | 1.5 | -0.3 | 0.8 | 1.4 |
| Extinction: sum of active levers before priming | 0.8 | 0.8 | 2.5 | -1.6 | -1.1 | -0.6 | -0.1 | -0.8 | 0.7 | -0.9 | -0.5 | 0.9 | -1.5 | -0.4 | 0.7 |
| Time in open arm after self-admin | 0.8 | 0.9 | 3.0 | -1.7 | -1.0 | -0.4 | -0.1 | -0.2 | 0.5 | -0.2 | -1.3 | 0.2 | -1.7 | -0.6 | 1.0 |
| Fecal boli incidents, locomotor time 1 | 0.8 | 0.9 | 2.9 | -0.8 | 0.8 | 1.2 | 0.3 | 1.7 | -1.0 | 1.6 | -0.5 | -0.1 | -0.5 | 0.6 | 0.7 |
| Run reversals in cocaine runway, females | 0.8 | 0.8 | 1.8 | 1.2 | 1.1 | 0.3 | 0.4 | 0.9 | -0.9 | 0.8 | 1.3 | -0.3 | 1.2 | 0.7 | -0.5 |
| Latency to leave start box in cocaine runway, F | 0.8 | 0.9 | 1.6 | -0.2 | -0.8 | -0.5 | -1.2 | -1.3 | 1.2 | -1.3 | -0.8 | -0.5 | -0.2 | -1.2 | -0.9 |
| Water consumed over 24 hours | 0.7 | 0.8 | 2.3 | 1.5 | 1.0 | 0.1 | 0.2 | 0.4 | -0.5 | 0.7 | 1.3 | -0.1 | 1.5 | 0.6 | -1.1 |
| Condit. Reinf. lever presses | 0.7 | 1.0 | 2.3 | -0.6 | 0.4 | 1.0 | 1.4 | 0.8 | -1.1 | 0.8 | 0.4 | 1.5 | -0.7 | 1.1 | 1.5 |
| Pavlov. Cond. lever latency | 0.7 | 0.9 | 2.5 | 1.2 | 0.1 | -0.5 | -1.3 | -0.5 | 0.8 | -0.5 | 0.2 | -1.2 | 1.3 | -0.7 | -1.6 |
| Lifetime Intake | 0.7 | 0.7 | 1.7 | -0.3 | 1.0 | -0.7 | 0.5 | 1.3 | -1.2 | 1.3 | 1.3 | 0.1 | -0.3 | 1.0 | -0.1 |
| Progressive ratio test 1 active lever presses | 0.7 | 0.7 | 1.6 | 0.1 | 1.1 | -0.8 | 0.2 | 1.3 | -1.0 | 1.3 | 0.8 | -0.2 | 0.1 | 0.8 | -0.8 |
| Context. condit. distance diff. score | 0.7 | 0.9 | 2.5 | 0.4 | -0.9 | -0.5 | -0.8 | -1.6 | 1.3 | -1.2 | -0.6 | -0.4 | 0.4 | -1.0 | -1.1 |
| Time in novel zone, NPP test | 0.7 | 0.7 | 1.7 | -0.4 | 0.1 | 1.1 | 1.2 | 0.4 | -0.7 | 0.6 | 1.1 | 1.3 | -0.4 | 0.8 | 1.0 |
| Total zone transitions, NPP test | 0.7 | 1.0 | 2.6 | 1.2 | 1.1 | -0.0 | 1.2 | 0.7 | -1.2 | 0.7 | 1.6 | 0.3 | 1.2 | 1.1 | -0.7 |
| Total resting periods, locomotor time 1 | 0.7 | 0.8 | 2.6 | -0.6 | 0.4 | 0.4 | 1.6 | 0.5 | -1.1 | 0.4 | 1.5 | 0.8 | -0.4 | 1.0 | 0.5 |
| Time >=10cm from walls, locomotor time 2 | 0.7 | 0.8 | 3.3 | -0.0 | -0.1 | 0.9 | 1.1 | -0.3 | -0.3 | 0.0 | 0.7 | 1.6 | 0.0 | 0.8 | 1.8 |
| Food seeking constrained by brief footshock | 0.7 | 0.8 | 2.4 | -1.4 | -1.1 | 0.1 | 0.0 | -1.1 | 0.7 | -0.6 | 0.2 | 1.2 | -1.6 | -0.5 | 0.8 |
| Times rat made contact with spout | 0.6 | 0.7 | 2.3 | 1.0 | 0.9 | -0.0 | 0.7 | 0.5 | -0.9 | 0.7 | 1.5 | 0.3 | 0.9 | 0.8 | -0.4 |
| Mean num. licks in bursts | 0.6 | 0.8 | 2.2 | 1.2 | 0.8 | -0.8 | -0.8 | 0.3 | -0.1 | 0.2 | 0.0 | -1.4 | 1.2 | -0.2 | -1.5 |
| Delay discounting water rate 18 sec | 0.6 | 0.8 | 1.5 | 1.2 | 1.2 | 0.5 | 0.6 | 0.8 | -1.0 | 0.8 | 1.2 | -0.0 | 1.2 | 0.9 | -0.4 |
| Intermittent access total infusions | 0.6 | 0.6 | 1.5 | -0.3 | 0.9 | -0.5 | 0.5 | 1.2 | -1.1 | 1.2 | 1.2 | 0.1 | -0.3 | 0.9 | -0.0 |
| Short access day 10 total inactive lever presses | 0.6 | 0.7 | 1.3 | 0.5 | 0.8 | 1.2 | 0.8 | 0.9 | -0.9 | 0.9 | 0.9 | 0.7 | 0.5 | 1.0 | 0.6 |
| Stereotopy head waving duration, day 7 | 0.6 | 0.8 | 1.3 | 0.0 | 0.7 | 0.9 | 1.1 | 1.0 | -1.0 | 1.1 | 1.0 | 0.7 | 0.1 | 1.1 | 1.1 |
| Bone: trabecular tissue density | 0.6 | 0.8 | 1.7 | 1.2 | 1.3 | 0.1 | -0.2 | 1.1 | -0.8 | 0.9 | 0.5 | -0.6 | 1.2 | 0.4 | -1.3 |
| Ambulatory time before self-admin | 0.6 | 0.6 | 2.5 | 1.6 | 0.8 | 0.4 | -0.3 | 0.3 | -0.1 | 0.9 | 0.2 | -0.3 | 1.5 | 0.4 | -0.9 |
| Area under the delay curve | 0.6 | 0.6 | 1.3 | -0.2 | 0.5 | 0.7 | 1.1 | 0.7 | -0.9 | 0.9 | 0.7 | 1.1 | -0.4 | 1.1 | 0.7 |
| Delay discount exponential model param | 0.6 | 0.7 | 1.4 | 0.2 | -0.5 | -0.7 | -1.2 | -0.7 | 1.0 | -0.9 | -0.8 | -1.2 | 0.4 | -1.1 | -0.7 |
| Progressive ratio | 0.6 | 0.7 | 1.7 | -1.1 | -1.0 | -0.9 | -0.9 | -0.4 | 0.9 | -0.5 | -1.3 | -0.2 | -1.3 | -0.8 | 0.1 |
| Latency to leave start box in cocaine runway | 0.6 | 0.7 | 1.2 | -0.7 | -0.8 | -0.6 | -1.0 | -1.0 | 1.0 | -1.1 | -0.4 | -0.2 | -0.5 | -1.1 | -0.8 |
| Mn content in liver | 0.6 | 0.7 | 1.5 | -0.4 | -1.1 | -0.7 | -0.8 | -1.1 | 1.2 | -1.2 | 0.2 | -0.1 | -0.4 | -1.0 | -0.5 |
| Na content in liver | 0.6 | 0.6 | 1.7 | -1.3 | -1.1 | -0.0 | -0.1 | -0.4 | 0.7 | -0.6 | -0.6 | 0.5 | -1.3 | -0.6 | 0.7 |
| Extensor digitorum longus weight | 0.5 | 2.1 | 6.0 | 0.5 | 0.8 | 1.9 | 1.9 | 1.0 | -1.4 | 0.8 | 2.4 | 1.8 | 0.5 | 1.4 | 1.5 |
| Delay discounting water rate 0 sec | 0.5 | 0.8 | 1.5 | 0.7 | 1.0 | 1.1 | 0.9 | 1.1 | -1.1 | 1.2 | 0.5 | 0.2 | 0.7 | 1.0 | 0.4 |
| Delay discounting water rate 6 sec | 0.5 | 0.7 | 2.2 | 1.4 | 1.0 | 0.4 | 0.4 | 0.7 | -0.7 | 1.0 | 0.2 | -0.4 | 1.5 | 0.6 | -0.7 |
| Reaction time mean minus median AUC | 0.5 | 0.6 | 1.5 | 0.8 | 1.2 | -0.3 | 0.1 | 1.1 | -0.9 | 0.7 | 0.9 | -0.1 | 1.0 | 0.8 | -0.7 |
| Reaction time premature initiation rate | 0.5 | 0.7 | 1.8 | 1.1 | 1.1 | -0.4 | -0.1 | 0.5 | -0.6 | 1.2 | 0.5 | -0.8 | 1.3 | 0.5 | -1.0 |
| Cocaine response before conditioning | 0.5 | 0.6 | 2.2 | -0.9 | -0.8 | 1.0 | 0.3 | -0.4 | 0.4 | -0.2 | -0.2 | 1.1 | -0.9 | -0.0 | 1.5 |
| Condit. Reinf. active-inactive response ratio | 0.5 | 0.5 | 1.8 | -1.1 | -0.1 | 0.5 | 0.6 | 0.6 | -0.6 | 0.1 | -0.2 | 0.2 | -1.1 | 0.1 | 1.3 |
| Pavlov. Cond. lever contacts | 0.5 | 0.7 | 1.7 | -0.4 | 0.4 | 0.5 | 1.3 | 0.6 | -1.0 | 0.9 | 0.2 | 1.1 | -0.5 | 1.0 | 1.0 |
| Conditioned reinforcement - inactives | 0.5 | 0.5 | 1.4 | 0.0 | 0.8 | 0.3 | 0.6 | 1.0 | -0.9 | 1.2 | 0.9 | 0.5 | 0.2 | 1.0 | 0.4 |
| Intermittent access day 1 locomotion | 0.5 | 0.5 | 2.2 | -0.3 | -0.1 | -1.5 | -0.5 | -0.4 | 0.3 | -0.5 | 0.4 | -0.8 | -0.1 | -0.5 | -1.2 |
| Intermittent access total locomotion | 0.5 | 0.5 | 1.4 | 0.5 | 0.9 | -0.8 | -0.3 | 0.8 | -0.5 | 0.5 | 0.5 | -1.1 | 0.6 | 0.2 | -1.2 |
| Short access day 1 total inactive lever presses | 0.5 | 0.6 | 1.2 | 0.7 | 0.7 | 0.5 | 0.8 | 0.5 | -0.7 | 0.6 | 1.1 | 1.0 | 0.7 | 0.9 | 0.2 |
| Short access day 1 total infusions | 0.5 | 0.5 | 0.9 | 0.8 | 1.0 | -0.6 | 0.1 | 1.0 | -0.7 | 0.9 | 0.8 | -0.3 | 0.7 | 0.6 | -0.8 |
| Stereotopy head waving duration, day 3 | 0.5 | 0.6 | 2.3 | -1.2 | -0.5 | 0.2 | -0.5 | 0.2 | 0.3 | 0.0 | -1.5 | 0.1 | -1.2 | -0.3 | 1.1 |
| Incentive salience index mean | 0.5 | 0.6 | 1.4 | -0.6 | -0.2 | -1.2 | -1.0 | 0.1 | 0.3 | -0.4 | -0.7 | -1.1 | -0.6 | -0.9 | -1.0 |
| Total locomotion distance, hab. session 2 | 0.5 | 0.6 | 1.3 | 1.1 | 1.0 | -0.0 | 0.8 | 0.5 | -0.9 | 0.9 | 0.5 | 0.2 | 1.1 | 1.0 | -0.7 |
| Breakpoint value in progressive ratio session | 0.5 | 0.6 | 2.3 | -0.8 | -0.5 | 0.3 | 1.1 | -0.3 | -0.2 | -0.2 | 0.6 | 1.5 | -0.8 | 0.5 | 1.1 |
| Distance traveled before self-admin | 0.5 | 0.5 | 1.2 | 1.1 | 0.1 | -0.3 | -1.0 | -0.4 | 0.7 | -0.1 | -0.4 | -0.8 | 1.0 | -0.4 | -1.0 |
| Delay disc. indifference point, 0s delay | 0.5 | 0.5 | 1.5 | 0.4 | 0.6 | 0.2 | 0.9 | 0.4 | -0.8 | 1.2 | 0.6 | 0.7 | 0.5 | 1.2 | -0.1 |
| Locomotion in novel chamber | 0.5 | 0.7 | 3.5 | 1.0 | 0.4 | -0.9 | -0.5 | -0.2 | 0.2 | -0.2 | 0.3 | -1.0 | 1.0 | -0.3 | -1.9 |
| K content in liver | 0.5 | 0.5 | 1.1 | -0.9 | -1.0 | -0.5 | -0.3 | -0.9 | 0.8 | -1.0 | 0.1 | -0.2 | -0.9 | -0.9 | -0.2 |
| Std. dev. time between licks in bursts | 0.4 | 0.5 | 1.3 | -1.1 | -0.9 | -0.9 | 0.4 | -0.7 | 0.3 | -0.7 | -0.7 | -0.2 | -1.1 | -0.3 | 0.4 |
| Indifference point AUC | 0.4 | 0.5 | 1.5 | -1.1 | -0.1 | 0.2 | 1.0 | 0.2 | -0.7 | 0.4 | -0.4 | 0.5 | -1.2 | 0.4 | 1.0 |
| Intermittent access terminal intake (last 3 days) | 0.4 | 0.5 | 1.5 | 0.0 | 0.8 | -0.3 | 0.5 | 0.8 | -0.8 | 1.0 | 1.2 | 0.4 | 0.1 | 0.9 | 0.1 |
| Short access total infusions | 0.4 | 0.4 | 1.4 | -0.2 | 0.7 | -1.2 | 0.0 | 0.9 | -0.7 | 0.8 | 0.7 | -0.4 | -0.3 | 0.5 | -0.7 |
| Short access day 1 locomotion | 0.4 | 0.4 | 1.1 | -0.1 | 0.8 | -0.7 | -0.0 | 1.1 | -0.8 | 1.0 | 0.6 | -0.3 | -0.2 | 0.5 | -0.7 |
| Compulsive drug intake | 0.4 | 0.4 | 1.3 | -1.1 | -0.7 | 0.1 | 0.2 | -0.6 | 0.3 | -0.6 | -0.3 | 0.7 | -0.9 | -0.1 | 0.8 |
| Locomotion velocity, session 3 | 0.4 | 0.5 | 2.0 | 0.6 | 0.6 | -0.8 | -0.8 | 0.3 | -0.1 | 0.1 | -0.3 | -1.1 | 0.6 | -0.4 | -1.4 |
| Condit. Reinf. lever presses | 0.4 | 0.6 | 1.3 | -0.8 | -0.2 | -1.0 | -1.0 | 0.3 | 0.3 | -0.4 | -0.7 | -1.2 | -0.8 | -0.9 | -0.7 |
| Delta time in open arm before/after self-admin | 0.4 | 0.3 | 0.9 | -0.7 | 0.1 | 0.5 | 0.9 | 0.4 | -0.6 | 0.1 | 0.6 | 0.7 | -0.5 | 0.4 | 0.8 |
| Active lever presses in extinction session 6 | 0.4 | 0.3 | 1.7 | 0.0 | 0.5 | 0.4 | 0.5 | 0.4 | -0.5 | 0.4 | 0.9 | 1.3 | -0.1 | 0.6 | 0.1 |
| Time in closed arm after self-admin | 0.4 | 0.4 | 0.9 | 0.3 | -0.5 | -0.8 | -0.4 | -0.9 | 0.7 | -0.9 | 0.1 | -0.4 | 0.2 | -0.6 | -1.0 |
| Delay discount hyperbolic model param | 0.4 | 0.4 | 1.0 | 0.0 | -0.3 | -0.5 | -1.0 | -0.4 | 0.7 | -0.7 | -0.6 | -1.0 | 0.3 | -0.9 | -0.5 |
| Vertical activity count, locomotor time 1 | 0.4 | 0.4 | 0.9 | 0.6 | -0.4 | 0.2 | -0.9 | -0.9 | 1.0 | -0.9 | -0.4 | 0.2 | 0.6 | -0.9 | -0.3 |
| Distance moved, locomotor task time 2 | 0.4 | 0.5 | 1.8 | -0.7 | 0.1 | 0.5 | 0.7 | 0.4 | -0.5 | 0.3 | 0.3 | 1.1 | -0.8 | 0.6 | 1.4 |
| Co content in liver | 0.4 | 0.5 | 1.9 | 0.3 | -0.2 | -0.6 | -0.8 | -0.1 | 0.5 | -0.7 | -0.6 | -1.4 | 0.3 | -0.9 | -0.8 |
| Mg content in liver | 0.4 | 0.4 | 1.0 | -1.0 | -0.7 | 0.0 | 0.4 | -0.5 | 0.2 | -0.8 | 0.9 | 0.6 | -1.0 | -0.3 | 0.6 |
| Tail length | 0.3 | 0.8 | 2.3 | 0.4 | 0.5 | 0.9 | 1.4 | 0.2 | -0.9 | 1.0 | 0.7 | 1.4 | 0.3 | 1.5 | 0.6 |
| Delay discounting time to switch 0 sec | 0.3 | 0.5 | 1.0 | -0.2 | -0.7 | -0.8 | -0.9 | -0.8 | 1.0 | -0.9 | -0.3 | -0.2 | -0.3 | -0.8 | -0.5 |
| Reaction time mean minus median | 0.3 | 0.4 | 1.7 | 0.0 | 1.1 | 0.0 | 0.1 | 1.3 | -1.0 | 0.6 | 0.4 | 0.2 | 0.2 | 0.7 | 0.1 |
| Reaction time mean | 0.3 | 0.4 | 1.4 | 0.3 | 0.9 | 0.2 | -0.4 | 1.2 | -0.6 | 1.0 | -0.2 | -0.2 | 0.4 | 0.5 | -0.3 |
| Median of all reaction times | 0.3 | 0.4 | 1.0 | 0.5 | 0.8 | 0.2 | -0.5 | 1.0 | -0.3 | 1.0 | -0.3 | -0.5 | 0.6 | 0.3 | -0.5 |
| Reaction time omissions | 0.3 | 0.4 | 1.2 | 0.2 | 0.5 | 0.5 | 1.0 | 0.6 | -0.8 | -0.0 | 1.1 | 0.5 | 0.4 | 0.7 | 0.6 |
| Reaction time false alarm rate | 0.3 | 0.4 | 1.0 | -0.4 | -0.6 | -1.0 | -0.5 | -0.7 | 0.6 | -0.8 | -0.5 | -0.7 | -0.4 | -0.5 | -0.8 |
| Intermittent access day 1 total infusions | 0.3 | 0.3 | 1.1 | -1.0 | -0.1 | -1.0 | 0.2 | 0.1 | -0.2 | 0.1 | 0.9 | 0.1 | -1.0 | 0.2 | -0.2 |
| Progressive ratio test 1 breakpoint | 0.3 | 0.3 | 0.8 | -0.4 | 0.6 | -0.9 | -0.1 | 0.8 | -0.6 | 0.8 | 0.4 | -0.3 | -0.4 | 0.4 | -0.5 |
| Short access day 10 total infusions | 0.3 | 0.4 | 1.8 | -0.6 | 0.3 | -1.4 | -0.4 | 0.6 | -0.3 | 0.5 | 0.1 | -0.6 | -0.6 | 0.1 | -0.8 |
| Condit. Reinf. active responses | 0.3 | 0.4 | 1.7 | -0.1 | 0.8 | 0.2 | 0.3 | 1.3 | -1.0 | 1.0 | 0.1 | -0.1 | -0.1 | 0.5 | 0.0 |
| Locomotion velocity, hab. session 2 | 0.3 | 0.4 | 0.9 | 1.0 | 0.8 | -0.2 | 0.5 | 0.3 | -0.6 | 0.7 | 0.2 | 0.1 | 1.0 | 0.8 | -0.9 |
| Total locomotion distance, NPP test | 0.3 | 0.5 | 1.1 | 0.9 | 0.5 | -0.2 | 1.1 | -0.0 | -0.7 | 0.5 | 0.8 | 0.6 | 0.8 | 1.0 | -0.6 |
| Pavlov. Cond. lever latency | 0.3 | 0.4 | 1.6 | -0.3 | -0.0 | 0.8 | 0.7 | 0.3 | -0.3 | 0.2 | 0.6 | 1.1 | -0.4 | 0.6 | 1.3 |
| Pavlov. Cond. index score | 0.3 | 0.3 | 0.8 | 0.8 | 0.7 | 0.2 | 0.3 | 0.3 | -0.5 | 0.6 | 0.7 | 0.2 | 0.9 | 0.5 | -0.5 |
| Pavlov. Cond. response bias | 0.3 | 0.3 | 0.8 | 0.9 | 0.8 | 0.0 | 0.2 | 0.4 | -0.5 | 0.7 | 0.5 | 0.0 | 0.9 | 0.5 | -0.7 |
| Bone: cortical porosity | 0.3 | 0.4 | 1.2 | -0.4 | -0.1 | 0.4 | 0.8 | -0.1 | -0.4 | -0.1 | 0.9 | 1.0 | -0.4 | 0.4 | 1.1 |
| Time in closed arm before self-admin | 0.3 | 0.4 | 1.3 | 1.2 | 0.3 | 0.6 | 0.4 | -0.3 | -0.2 | -0.5 | 0.8 | 0.1 | 1.1 | 0.3 | -0.3 |
| Time to tail flick, vehicle, after self-admin | 0.3 | 0.3 | 0.8 | 0.6 | 0.7 | 0.3 | -0.4 | 0.9 | -0.3 | 0.7 | -0.5 | -0.7 | 0.7 | -0.0 | -0.5 |
| Rest time, locomotor task time 1 | 0.3 | 0.3 | 1.1 | 0.4 | 0.6 | -0.8 | 0.1 | 0.4 | -0.5 | 0.2 | 0.0 | -1.0 | 0.5 | 0.1 | -1.1 |
| Distance moved, locomotor task time 1 | 0.3 | 0.3 | 1.7 | 0.2 | -0.0 | 0.9 | 0.2 | 0.1 | 0.0 | -0.3 | 0.5 | 1.3 | 0.0 | 0.2 | 0.7 |
| Vertical activity count, locomotor time 2 | 0.3 | 0.4 | 0.9 | 0.1 | 0.3 | 0.8 | 0.7 | 0.5 | -0.5 | 0.7 | -0.3 | 0.7 | 0.1 | 0.6 | 1.0 |
| Seeking ratio, delayed vs. immediate footshock | 0.3 | 0.4 | 1.3 | -0.0 | -0.5 | -1.1 | -0.3 | -0.9 | 0.5 | -0.5 | 0.2 | -0.6 | -0.1 | -0.5 | -0.9 |
| Seeking ratio, punishment vs. effort | 0.3 | 0.3 | 1.9 | 0.3 | 0.2 | 0.6 | 0.7 | -0.5 | -0.3 | -0.0 | 1.4 | 0.6 | 0.4 | 0.4 | 0.1 |
| Indifference point function ln k | 0.2 | 0.3 | 1.0 | 0.9 | 0.4 | 0.3 | -0.5 | 0.2 | 0.1 | 0.1 | 0.6 | -0.5 | 1.0 | -0.1 | -0.3 |
| Indifference point function log k | 0.2 | 0.3 | 1.0 | 0.9 | 0.4 | 0.3 | -0.5 | 0.2 | 0.1 | 0.1 | 0.6 | -0.5 | 1.0 | -0.1 | -0.3 |
| Saline control response | 0.2 | 0.3 | 1.1 | -0.2 | 0.1 | -0.7 | -1.0 | 0.4 | 0.2 | 0.1 | -0.6 | -1.0 | -0.2 | -0.5 | -0.8 |
| Intermitt. access escalation Index | 0.2 | 0.1 | 0.5 | 0.6 | 0.2 | 0.2 | 0.2 | -0.1 | -0.0 | -0.1 | 0.7 | 0.5 | 0.7 | 0.2 | -0.1 |
| Progressive ratio test 1 inactive lever presses | 0.2 | 0.2 | 0.5 | -0.0 | 0.5 | -0.0 | 0.2 | 0.5 | -0.4 | 0.7 | 0.5 | 0.6 | 0.1 | 0.6 | -0.1 |
| Number of responses in last shaping day | 0.2 | 0.2 | 0.6 | 0.3 | 0.3 | -0.5 | -0.2 | 0.3 | -0.2 | 0.3 | 0.7 | -0.6 | 0.2 | 0.1 | -0.5 |
| Degree of sensitization stereotypy | 0.2 | 0.2 | 0.7 | -0.2 | -0.1 | 0.2 | 0.7 | -0.1 | -0.2 | 0.2 | 0.8 | 0.4 | -0.1 | 0.4 | 0.7 |
| Time in familiar zone, hab. session 1 | 0.2 | 0.2 | 0.9 | 0.2 | 0.1 | -0.0 | -0.9 | 0.2 | 0.3 | -0.4 | -0.1 | -0.9 | 0.2 | -0.6 | -0.5 |
| Novel to familiar place preference ratio | 0.2 | 0.2 | 0.5 | -0.6 | -0.2 | 0.6 | 0.5 | 0.0 | -0.1 | 0.1 | 0.5 | 0.7 | -0.5 | 0.1 | 0.5 |
| Novelty place preference | 0.2 | 0.3 | 0.7 | -0.4 | -0.1 | 0.7 | 0.7 | 0.1 | -0.3 | 0.3 | 0.7 | 0.8 | -0.4 | 0.4 | 0.6 |
| Locomotion velocity, NPP test | 0.2 | 0.3 | 1.0 | 0.9 | 0.3 | -0.7 | 0.4 | -0.4 | -0.2 | 0.0 | 0.3 | 0.1 | 0.9 | 0.4 | -1.0 |
| Pavlov. Cond. magazine entry latency | 0.2 | 0.3 | 0.5 | 0.7 | 0.6 | -0.0 | 0.6 | 0.2 | -0.5 | 0.7 | 0.7 | 0.6 | 0.7 | 0.7 | -0.1 |
| Pavlov. Cond. latency score | 0.2 | 0.2 | 0.6 | 0.7 | 0.6 | 0.0 | 0.2 | 0.2 | -0.4 | 0.4 | 0.6 | -0.1 | 0.8 | 0.3 | -0.6 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.2 | 0.2 | 0.5 | 0.6 | 0.5 | 0.2 | 0.4 | 0.2 | -0.5 | 0.5 | 0.6 | 0.3 | 0.7 | 0.4 | -0.3 |
| Bone: connectivity density | 0.2 | 0.3 | 0.9 | -0.2 | -0.2 | 0.8 | 0.6 | -0.3 | -0.1 | -0.4 | 0.9 | 0.6 | -0.2 | 0.1 | 0.9 |
| Bone: tissue strength | 0.2 | 0.2 | 0.4 | -0.7 | -0.6 | -0.1 | -0.1 | -0.6 | 0.5 | -0.6 | -0.2 | 0.3 | -0.7 | -0.4 | 0.5 |
| Delay disc. indifference point, 16s delay | 0.2 | 0.2 | 1.0 | -0.9 | -0.4 | 0.0 | 0.4 | -0.1 | -0.0 | -0.2 | 0.1 | 0.7 | -1.0 | -0.0 | 0.1 |
| Delay disc. indifference point, 4s delay | 0.2 | 0.2 | 0.5 | -0.5 | -0.6 | -0.2 | 0.3 | -0.6 | 0.3 | -0.5 | -0.7 | 0.3 | -0.6 | -0.1 | -0.0 |
| Rest time, locomotor task time 2 | 0.2 | 0.2 | 0.8 | 0.6 | 0.5 | 0.1 | -0.4 | 0.4 | -0.2 | 0.3 | 0.5 | -0.4 | 0.6 | -0.1 | -0.9 |
| Latency to leave start box in cocaine runway, M | 0.2 | 0.2 | 0.6 | -0.7 | 0.2 | -0.3 | 0.3 | 0.4 | -0.4 | 0.4 | 0.8 | 0.3 | -0.3 | 0.3 | -0.2 |
| Se content in liver | 0.2 | 0.2 | 0.6 | -0.8 | -0.6 | 0.1 | -0.5 | -0.3 | 0.5 | -0.5 | 0.1 | -0.1 | -0.8 | -0.6 | -0.1 |
| Tibialis anterior weight | 0.1 | 0.4 | 1.3 | -1.1 | -0.3 | 0.5 | 0.3 | 0.1 | -0.1 | -0.3 | 0.7 | 0.4 | -1.1 | -0.0 | 1.0 |
| Food consumed during 24 hour testing period | 0.1 | 0.1 | 0.4 | 0.6 | 0.1 | 0.2 | -0.2 | -0.2 | 0.2 | -0.2 | 0.5 | 0.1 | 0.6 | -0.1 | -0.6 |
| Mean time between licks in bursts | 0.1 | 0.2 | 0.5 | -0.5 | -0.3 | 0.4 | 0.6 | 0.0 | -0.1 | -0.0 | -0.0 | 0.7 | -0.5 | 0.3 | 0.7 |
| Reaction time num false alarms | 0.1 | 0.1 | 0.3 | -0.1 | -0.2 | -0.5 | 0.2 | -0.3 | 0.1 | -0.5 | 0.1 | -0.3 | -0.2 | 0.0 | -0.5 |
| Reaction time num false alarms AUC | 0.1 | 0.1 | 0.6 | 0.2 | -0.0 | -0.6 | 0.0 | -0.2 | -0.0 | -0.2 | 0.1 | -0.5 | 0.0 | 0.1 | -0.8 |
| Reaction time mean AUC | 0.1 | 0.2 | 0.6 | -0.2 | 0.5 | -0.0 | -0.6 | 0.8 | -0.1 | 0.6 | -0.4 | -0.3 | -0.1 | 0.1 | -0.2 |
| Conditioned locomotion | 0.1 | 0.1 | 0.4 | -0.2 | -0.2 | -0.5 | -0.6 | -0.3 | 0.4 | -0.2 | -0.2 | -0.5 | -0.2 | -0.3 | -0.3 |
| Pavlov. Cond. intertrial magazine entries | 0.1 | 0.1 | 0.4 | 0.3 | 0.2 | 0.7 | 0.4 | 0.2 | -0.3 | 0.2 | 0.4 | 0.5 | 0.3 | 0.3 | 0.4 |
| Intermitt. access day 15 inactive lever presses | 0.1 | 0.1 | 0.2 | -0.0 | 0.4 | 0.1 | 0.2 | 0.5 | -0.4 | 0.5 | 0.4 | 0.3 | 0.1 | 0.3 | 0.1 |
| Stereotopy head waving bouts, day 3 | 0.1 | 0.2 | 0.5 | -0.2 | 0.3 | 0.2 | -0.0 | 0.6 | -0.3 | 0.6 | -0.7 | 0.2 | -0.2 | 0.3 | 0.7 |
| Locomotion velocity, session 7 | 0.1 | 0.2 | 0.4 | 0.3 | 0.3 | 0.4 | 0.6 | 0.1 | -0.4 | 0.2 | 0.5 | 0.3 | 0.3 | 0.5 | 0.5 |
| Locomotion distance, session 7 | 0.1 | 0.1 | 0.3 | 0.5 | -0.2 | -0.2 | -0.1 | -0.5 | 0.3 | -0.4 | -0.3 | -0.2 | 0.4 | -0.1 | -0.4 |
| Stereotopy head waving bouts, day 7 | 0.1 | 0.1 | 0.6 | -0.2 | -0.0 | 0.2 | 0.5 | 0.0 | -0.2 | 0.4 | 0.4 | 0.4 | -0.1 | 0.5 | 0.8 |
| Condit. Reinf. active minus inactive responses | 0.1 | 0.1 | 0.5 | -0.2 | 0.1 | -0.6 | -0.5 | 0.3 | 0.0 | -0.0 | -0.3 | -0.4 | -0.2 | -0.4 | -0.7 |
| Condit. Reinf. active-inactive response ratio | 0.1 | 0.1 | 0.4 | -0.4 | -0.1 | -0.3 | -0.5 | 0.1 | 0.2 | -0.5 | 0.1 | -0.3 | -0.4 | -0.6 | -0.3 |
| Total locomotion distance, hab. session 1 | 0.1 | 0.1 | 0.3 | 0.2 | 0.0 | -0.3 | 0.3 | -0.2 | -0.1 | 0.5 | -0.2 | 0.3 | 0.2 | 0.5 | -0.3 |
| Locomotion velocity, hab. session 1 | 0.1 | 0.1 | 0.4 | 0.1 | -0.2 | -0.6 | 0.0 | -0.4 | 0.2 | 0.2 | -0.5 | 0.0 | 0.0 | 0.2 | -0.5 |
| Pavlov. Cond. change in total contacts | 0.1 | 0.2 | 0.6 | 0.7 | 0.3 | 0.0 | 0.0 | -0.1 | -0.0 | 0.0 | 0.4 | -0.2 | 0.7 | -0.1 | -0.8 |
| Pavlov. Cond. lever contacts | 0.1 | 0.1 | 0.4 | -0.0 | 0.0 | -0.3 | -0.4 | -0.0 | 0.1 | -0.1 | -0.3 | -0.6 | 0.0 | -0.3 | -0.6 |
| Pavlov. Cond. intertrial magazine entries | 0.1 | 0.1 | 0.3 | -0.0 | 0.4 | -0.1 | -0.1 | 0.5 | -0.4 | 0.3 | 0.1 | -0.6 | 0.0 | 0.1 | -0.3 |
| Bone: elastic displacement | 0.1 | 0.1 | 0.3 | -0.4 | -0.4 | 0.1 | 0.2 | -0.5 | 0.2 | -0.2 | -0.1 | 0.5 | -0.4 | -0.1 | 0.3 |
| Bone: post-yield work | 0.1 | 0.2 | 0.8 | -0.3 | -0.3 | 0.2 | 0.9 | -0.4 | -0.2 | -0.3 | 0.4 | 0.7 | -0.3 | 0.2 | 0.7 |
| Bone: trabecular spacing | 0.1 | 0.1 | 0.6 | -0.5 | -0.3 | 0.0 | -0.3 | 0.0 | 0.3 | 0.2 | -0.8 | 0.1 | -0.5 | -0.2 | -0.2 |
| Delta time in closed arm before/after self-admin | 0.1 | 0.1 | 0.4 | 0.3 | -0.0 | -0.6 | -0.6 | -0.1 | 0.3 | 0.1 | -0.2 | -0.3 | 0.2 | -0.2 | -0.7 |
| Delta time to tail flick, vehicle, before/after SA | 0.1 | 0.1 | 0.5 | 0.2 | -0.0 | -0.2 | -0.5 | -0.2 | 0.3 | 0.1 | -0.5 | -0.5 | 0.3 | -0.5 | -0.7 |
| Delay disc. indifference point, 2s delay | 0.1 | 0.1 | 0.5 | 0.3 | -0.3 | -0.2 | 0.2 | -0.7 | 0.2 | -0.2 | 0.3 | 0.4 | 0.1 | 0.3 | -0.1 |
| Cu content in liver | 0.1 | 0.2 | 0.5 | 0.5 | 0.5 | -0.0 | -0.1 | 0.2 | -0.3 | -0.1 | 0.7 | -0.4 | 0.5 | -0.1 | -0.5 |
| Fe content in liver | 0.1 | 0.1 | 0.4 | -0.5 | -0.1 | 0.0 | -0.0 | 0.1 | -0.0 | 0.2 | -0.6 | -0.2 | -0.5 | 0.0 | -0.1 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.