Hub : Genes

Nudcd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000083191 0.03 0.02 9.5e-04 0.02 0.02 0.01 0.01 6.4e-03 4.6e-03 2.1e-02 2.5e-02
2 Adipose alternative polyA ENSRNOT00000107496 0.05 0.03 6.1e-06 0.04 0.04 0.04 0.04 5.4e-05 1.2e-05 1.5e-05 2.8e-05
3 Adipose alternative polyA ENSRNOT00000107496 0.05 0.03 4.6e-06 0.04 0.05 0.04 0.04 2.1e-05 6.1e-06 1.0e-05 1.4e-05
4 Adipose gene expression ENSRNOG00000056148 0.16 0.08 8.3e-16 0.12 0.12 0.1 0.12 6.2e-13 1.1e-13 7.2e-11 4.4e-13
5 Adipose isoform ratio ENSRNOT00000083191 0.04 0.02 4.1e-04 0.02 0.02 0.02 0.02 1.3e-03 1.1e-03 2.5e-03 4.1e-03
6 Adipose isoform ratio ENSRNOT00000098063 0.03 0.02 1.6e-03 0.02 0.02 0.02 0.02 1.4e-03 1.4e-03 2.9e-03 1.6e-03
7 Adipose isoform ratio ENSRNOT00000107496 0.12 0.06 7.2e-16 0.13 0.13 0.13 0.14 7.5e-14 1.7e-14 1.2e-14 5.9e-15
8 Adipose mRNA stability ENSRNOG00000056148 0.04 0.03 1.1e-03 0.02 0.02 0.02 0.02 1.7e-03 1.6e-03 2.1e-03 1.9e-03
9 BLA gene expression ENSRNOG00000056148 0.07 0.05 5.7e-03 0.01 0.03 0.01 0.01 5.8e-02 1.0e-02 1.3e-01 1.3e-01
10 Brain gene expression ENSRNOG00000056148 0.08 0.05 5.2e-10 0.08 0.1 0.1 0.1 4.4e-08 3.5e-09 4.0e-09 2.9e-09
11 Brain mRNA stability ENSRNOG00000056148 0.07 0.05 5.3e-06 0.04 0.06 0.05 0.05 9.4e-05 7.2e-06 1.7e-05 1.3e-05
12 LHb gene expression ENSRNOG00000056148 0.33 0.16 5.1e-05 0.18 0.06 0.11 0.16 5.6e-05 1.3e-02 1.7e-03 1.5e-04
13 Liver gene expression ENSRNOG00000056148 0.13 0.07 7.5e-11 0.06 0.08 0.08 0.08 3.3e-07 3.1e-09 3.3e-09 4.8e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.10.20.90.50.50.5-0.30.5-0.90.6-0.2-0.50.0-0.2-0.2-0.2
BMI without tail0.00.00.0-0.1-0.1-0.10.1-0.1-0.00.0-0.10.00.1-0.2-0.10.2
Body weight1.66.910.32.92.92.9-2.62.9-3.23.0-2.0-2.4-2.3-2.4-2.3-1.9
Epididymis fat weight0.20.41.1-0.3-0.3-0.30.5-0.4-0.4-0.00.90.50.81.10.90.1
Glucose6.910.532.50.51.01.1-0.00.9-0.20.8-5.7-4.4-5.2-4.7-5.02.7
Heart weight0.50.71.8-1.0-0.9-0.91.3-1.01.0-1.00.1-0.00.30.70.41.4
Left kidney weight0.30.82.91.11.00.9-1.21.0-0.80.60.80.20.30.40.5-1.7
Right kidney weight0.41.34.10.40.20.2-0.40.2-0.50.12.01.11.61.71.7-1.4
Tail length1.03.14.91.71.81.7-1.91.8-1.31.8-1.8-1.4-2.0-2.2-2.0-1.3
Length with tail2.07.38.92.93.03.0-3.03.0-2.72.8-2.1-2.3-2.7-2.7-2.5-2.3
Length without tail1.22.63.71.81.81.8-1.71.8-1.91.7-1.1-1.4-1.5-1.5-1.4-1.4
Liver weight, left1.32.15.0-1.0-1.1-1.20.6-1.00.5-1.02.22.22.01.82.1-0.4
Liver weight, right2.44.011.4-0.6-0.9-1.0-0.1-0.80.3-1.03.43.22.92.43.0-1.7
Parametrial fat weight1.12.14.11.21.31.3-1.21.3-1.31.3-1.8-1.5-2.0-1.9-1.8-0.4
Retroperitoneal fat weight0.10.51.10.90.80.8-0.90.8-1.10.60.2-0.20.0-0.10.0-1.0
Intraocular pressure0.20.30.60.40.50.5-0.30.5-0.20.6-0.7-0.8-0.6-0.7-0.7-0.0
Extensor digitorum longus weight2.28.913.72.62.72.8-2.42.7-2.82.9-3.5-3.2-3.7-3.7-3.6-0.9
Soleus weight1.13.25.02.12.12.0-2.12.1-2.22.2-0.7-1.1-1.2-1.4-1.0-2.0
Tibialis anterior weight0.93.05.01.51.61.7-1.11.5-1.91.6-2.1-2.2-2.0-1.9-2.1-0.2
Tibia length0.30.92.41.00.80.8-1.00.8-1.51.00.90.30.50.40.6-1.6
Number of licking bursts2.93.44.72.02.12.1-1.72.0-1.52.1-1.6-2.2-1.9-1.6-1.8-1.2
Food consumed during 24 hour testing period1.01.13.40.30.40.5-0.20.40.00.3-1.8-1.4-1.7-1.6-1.70.7
Times rat made contact with spout2.62.99.2-2.0-1.9-1.82.4-1.92.2-1.8-0.8-0.3-0.40.3-0.23.0
Mean time between licks in bursts0.20.31.0-0.2-0.1-0.00.3-0.10.40.1-0.9-0.7-1.0-0.6-0.70.8
Mean num. licks in bursts4.75.78.7-2.9-2.9-2.82.9-2.82.6-2.90.81.61.31.51.42.8
Std. dev. time between licks in bursts0.00.00.10.10.10.10.00.00.30.2-0.2-0.3-0.3-0.1-0.20.1
Water consumed over 24 hours0.70.82.40.00.20.20.20.10.20.0-1.5-1.3-1.5-1.1-1.31.0
Indifference point 0 sec1.52.47.51.11.31.4-0.31.1-0.91.0-2.2-2.7-2.0-1.5-2.00.7
Indifference point AUC0.10.20.4-0.3-0.2-0.20.3-0.20.5-0.4-0.5-0.3-0.5-0.4-0.40.6
Indifference point function ln k0.20.31.00.70.60.6-0.80.6-0.80.60.30.10.1-0.10.1-1.0
Indifference point function log k0.20.31.00.70.60.6-0.80.6-0.80.60.30.10.1-0.10.1-1.0
Delay discounting total patch changes 0 sec1.62.58.11.11.21.4-0.31.1-0.81.0-2.3-2.8-2.0-1.6-2.10.8
Delay discounting total patch changes 12 sec0.91.23.70.40.60.70.10.5-0.60.6-1.7-1.9-1.5-1.2-1.41.0
Delay discounting total patch changes 18 sec1.31.86.10.60.80.90.10.7-0.40.4-2.1-2.5-1.9-1.4-1.81.1
Delay discounting total patch changes 24 sec1.41.74.7-1.4-1.3-1.21.9-1.41.7-1.5-0.0-0.20.60.90.52.2
Delay discounting total patch changes 6 sec1.52.36.20.81.01.1-0.30.9-0.80.9-2.4-2.5-2.1-1.8-2.10.9
Delay discounting time to switch 0 sec0.20.41.0-0.3-0.4-0.40.2-0.40.0-0.31.00.91.00.80.9-0.2
Delay discounting water rate 0 sec1.21.94.80.70.90.9-0.40.8-0.60.7-2.2-1.9-2.0-1.9-2.00.6
Delay discounting water rate 12 sec0.10.10.30.30.30.3-0.20.3-0.10.1-0.5-0.5-0.6-0.5-0.50.0
Delay discounting water rate 18 sec0.71.03.51.11.00.9-1.41.0-1.20.90.70.50.40.00.3-1.9
Delay discounting water rate 24 sec0.00.10.2-0.3-0.2-0.20.0-0.20.1-0.3-0.30.2-0.3-0.5-0.30.2
Delay discounting water rate 6 sec0.30.51.20.80.70.7-1.10.8-0.40.4-0.4-0.1-0.7-0.9-0.5-1.0
Locomotor activity0.30.51.3-0.2-0.1-0.00.5-0.10.30.2-1.1-1.1-0.7-0.7-0.91.1
Locomotor testing distance0.30.51.20.80.80.8-0.70.8-0.71.1-0.3-0.7-0.3-0.4-0.4-0.6
Locomotor testing rearing1.11.83.60.91.01.1-0.61.0-0.91.1-1.9-1.9-1.8-1.7-1.80.3
Light reinforcement 10.20.30.60.70.70.7-0.80.7-0.50.5-0.3-0.4-0.4-0.5-0.3-0.7
Light reinforcement 21.11.45.21.41.31.2-1.71.4-1.01.10.60.20.2-0.10.2-2.3
Reaction time number correct0.10.20.7-0.4-0.3-0.30.5-0.30.5-0.5-0.6-0.4-0.2-0.3-0.30.8
Reaction time mean minus median2.33.04.4-1.9-1.9-1.82.1-1.92.0-2.01.11.01.41.71.41.8
Reaction time mean minus median AUC1.72.23.2-1.5-1.5-1.51.8-1.61.8-1.61.00.81.31.61.31.5
Reaction time num false alarms1.21.62.81.51.51.5-1.31.5-1.61.7-0.7-1.1-0.9-0.9-0.9-1.1
Reaction time num false alarms AUC1.62.34.11.81.81.8-1.61.8-2.02.0-0.5-1.1-0.7-0.8-0.7-1.6
Reaction time trials correct on left0.10.20.7-0.4-0.3-0.30.5-0.30.5-0.5-0.6-0.4-0.2-0.3-0.30.8
Reaction time trials on left0.10.20.7-0.4-0.3-0.30.5-0.30.5-0.5-0.5-0.4-0.2-0.2-0.30.9
Reaction time mean0.50.71.2-0.8-0.8-0.80.8-0.90.6-0.60.90.91.11.10.90.4
Reaction time mean AUC0.81.12.1-0.9-0.9-1.00.8-1.00.7-0.71.31.21.41.41.30.3
Median of all reaction times0.20.30.8-0.4-0.4-0.50.2-0.40.1-0.10.80.90.90.70.6-0.1
Reaction time omissions0.50.71.7-0.6-0.7-0.70.8-0.70.5-0.60.90.61.31.21.00.5
Reaction time false alarm rate1.72.44.31.91.91.8-1.81.8-2.12.1-0.2-0.9-0.6-0.6-0.6-1.9
Reaction time premature initiation rate1.92.54.7-1.3-1.4-1.50.9-1.41.3-1.62.02.21.91.82.00.0
Reaction time premature initiations1.21.72.3-1.3-1.3-1.41.0-1.31.3-1.51.31.51.41.31.40.5
Std. dev. reaction times1.21.72.5-1.3-1.3-1.31.5-1.41.3-1.31.10.81.31.61.31.2
Reaction time trials completed0.10.20.7-0.4-0.3-0.30.5-0.30.5-0.5-0.5-0.4-0.2-0.2-0.30.9
Reaction time trials AUC0.10.20.5-0.3-0.2-0.20.4-0.20.4-0.4-0.6-0.4-0.3-0.3-0.40.7
Social response proportion1.01.02.30.80.90.8-1.00.9-1.10.9-1.2-0.7-1.4-1.5-1.2-0.5
Social responses1.51.94.30.91.01.0-0.91.0-1.21.1-2.0-1.5-1.8-2.1-1.90.1
Social time0.20.30.80.20.30.3-0.20.3-0.70.4-0.9-0.6-0.7-0.9-0.80.3
Conditioned locomotion0.60.72.10.50.30.3-0.70.4-0.40.11.31.01.10.81.0-1.4
Cocaine response after cond. corrected1.21.31.91.31.31.4-1.11.3-0.91.4-1.0-1.3-1.0-1.0-1.1-0.8
Cocaine response after cond. not corrected1.71.82.91.61.61.6-1.31.6-1.31.7-0.9-1.4-1.0-1.0-1.1-1.1
Cocaine response before conditioning0.20.20.6-0.1-0.1-0.10.1-0.1-0.2-0.00.80.50.70.70.7-0.3
Saline control response0.50.71.4-0.9-0.9-0.91.0-0.91.2-1.00.30.40.60.60.51.0
Condit. Reinf. active minus inactive responses0.30.30.6-0.5-0.5-0.50.4-0.50.6-0.80.60.60.80.60.60.2
Condit. Reinf. active-inactive response ratio0.10.10.30.50.40.4-0.50.5-0.30.10.1-0.10.1-0.1-0.1-0.6
Condit. Reinf. active responses0.50.71.1-0.8-0.9-0.90.7-0.80.8-1.10.81.01.00.80.90.4
Condit. Reinf. inactive responses1.31.62.1-1.4-1.5-1.51.4-1.41.4-1.40.91.11.11.11.11.1
Condit. Reinf. lever presses0.20.30.6-0.4-0.4-0.40.4-0.40.6-0.80.70.50.80.70.70.1
Condit. Reinf. lever reinforcers received0.30.50.8-0.6-0.7-0.70.5-0.60.6-0.90.70.80.90.70.80.2
Pavlov. Cond. lever latency4.25.78.42.62.62.6-2.62.6-2.92.9-1.5-1.7-2.1-2.2-1.9-2.2
Pavlov. Cond. magazine entry latency0.00.00.1-0.1-0.1-0.10.1-0.10.4-0.30.1-0.00.20.20.10.0
Pavlov. Cond. change in total contacts0.40.51.0-0.7-0.7-0.70.7-0.70.9-1.00.50.60.60.60.60.5
Pavlov. Cond. index score1.41.82.8-1.3-1.4-1.41.3-1.41.6-1.71.11.11.41.41.20.9
Pavlov. Cond. latency score1.21.52.3-1.2-1.2-1.21.1-1.21.5-1.51.11.11.31.31.20.7
Pavlov. Cond. lever contacts3.65.08.0-2.4-2.4-2.42.4-2.42.8-2.71.51.72.02.11.91.9
Pavlov. Cond. magazine entry number0.50.61.60.90.80.8-1.00.9-1.01.00.30.1-0.1-0.20.0-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.10.30.30.3-0.30.3-0.30.3-0.1-0.1-0.3-0.2-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.1.31.72.7-1.3-1.3-1.31.3-1.41.5-1.61.11.11.31.41.20.9
Pavlov. Cond. response bias2.12.95.4-1.9-1.9-1.81.9-1.92.3-2.10.91.01.31.41.21.7
Conditioned reinforcement - actives0.00.00.1-0.3-0.3-0.30.0-0.2-0.0-0.1-0.00.3-0.0-0.20.00.1
Conditioned reinforcement - inactives0.00.00.10.20.20.2-0.20.2-0.20.2-0.1-0.2-0.3-0.1-0.2-0.2
Conditioned locomotion0.10.10.4-0.0-0.0-0.0-0.30.1-0.5-0.0-0.20.3-0.1-0.6-0.1-0.1
Intermittent access intake day 1-15 change0.40.41.2-0.2-0.1-0.00.5-0.1-0.0-0.1-1.0-1.0-0.7-0.6-0.71.1
Intermittent access intake escalation0.30.31.3-0.3-0.2-0.10.6-0.20.1-0.2-0.8-0.8-0.5-0.4-0.51.1
Intermittent access intake escalation 20.50.41.9-0.6-0.5-0.40.9-0.50.6-0.3-0.8-0.7-0.5-0.2-0.41.4
Intermitt. access day 1 inactive lever presses0.40.41.3-0.0-0.1-0.2-0.4-0.10.2-0.21.01.10.80.60.8-0.9
Intermitt. access day 15 inactive lever presses0.80.91.90.60.70.7-0.50.7-0.90.9-1.4-1.1-1.1-1.4-1.30.1
Intermitt. access escalation Index0.30.31.1-0.3-0.2-0.20.5-0.20.2-0.1-0.9-0.7-0.5-0.5-0.61.1
Intermittent access day 1 total infusions0.20.20.60.0-0.0-0.1-0.2-0.00.20.10.80.60.60.60.6-0.7
Intermittent access day 15 total infusions0.10.10.30.10.20.20.00.1-0.40.4-0.4-0.5-0.3-0.2-0.30.2
Intermittent access terminal intake (last 3 days)0.10.10.7-0.3-0.2-0.20.5-0.30.10.0-0.5-0.6-0.2-0.1-0.20.8
Intermittent access total infusions0.00.00.10.10.10.1-0.00.1-0.30.3-0.1-0.2-0.00.0-0.10.0
Intermittent access day 1 locomotion0.91.03.4-0.7-0.8-0.90.1-0.70.7-1.11.31.81.10.81.1-0.5
Intermittent access day 15 total locomotion0.20.20.90.50.50.4-0.60.5-0.90.2-0.3-0.0-0.4-0.5-0.3-0.5
Intermittent access total locomotion0.30.30.70.50.50.5-0.90.6-0.60.3-0.20.1-0.4-0.6-0.4-0.9
Intermittent access standard deviation2.93.14.8-2.2-2.1-2.12.1-2.12.1-2.00.61.21.11.11.02.0
Cocaine induced anxiety1.92.24.71.01.11.1-1.11.2-1.31.3-2.0-1.5-2.2-2.1-2.0-0.2
Post-drug Anxiety0.50.51.60.40.50.5-0.50.5-0.00.5-1.0-0.8-1.3-1.0-1.1-0.1
Baseline Anxiety0.20.20.70.10.10.1-0.00.00.2-0.00.80.20.60.90.6-0.4
Lifetime Intake0.00.00.10.10.10.1-0.10.1-0.30.3-0.1-0.1-0.0-0.1-0.1-0.0
Incentive Sensitization - Responses0.10.10.30.10.10.20.20.1-0.60.2-0.1-0.6-0.10.20.00.3
Incentive Sensitization - Breakpoint0.10.10.40.10.10.20.30.0-0.60.2-0.1-0.6-0.00.30.10.4
Progressive ratio test 1 active lever presses0.00.00.1-0.0-0.0-0.1-0.2-0.00.30.10.10.20.1-0.00.0-0.3
Progressive ratio test 1 breakpoint0.10.20.4-0.3-0.3-0.30.0-0.30.6-0.20.50.60.50.40.4-0.3
Progressive ratio test 1 inactive lever presses2.72.94.71.71.71.7-2.21.8-2.02.0-1.2-0.7-1.5-2.0-1.5-1.8
Progressive ratio test 2 active lever presses0.00.00.20.10.10.2-0.00.1-0.10.40.1-0.3-0.00.20.0-0.1
Progressive ratio test 2 breakpoint0.00.00.10.10.10.10.10.0-0.10.3-0.1-0.4-0.10.1-0.10.1
Progressive ratio test 2 inactive lever presses0.50.61.20.70.80.7-0.90.8-1.10.8-0.6-0.5-0.7-0.9-0.7-0.6
Total sessions with >9 infusions0.00.00.1-0.3-0.3-0.30.3-0.30.2-0.00.10.20.20.10.20.2
Short access day 1 total inactive lever presses2.52.84.51.61.71.6-1.91.7-1.41.6-1.6-1.2-1.8-2.1-1.8-1.3
Short access day 10 total inactive lever presses0.10.10.4-0.1-0.2-0.2-0.1-0.10.2-0.10.40.60.30.20.3-0.4
Short access day 1 total infusions0.40.41.3-0.5-0.5-0.60.1-0.50.5-0.70.81.20.80.40.7-0.2
Short access day 10 total infusions0.20.20.6-0.2-0.3-0.30.1-0.30.3-0.20.80.70.80.70.7-0.3
Short access total infusions0.40.40.7-0.6-0.6-0.70.5-0.60.5-0.50.70.80.80.60.70.2
Short access day 1 locomotion1.01.12.5-0.5-0.7-0.70.2-0.60.9-0.91.61.61.41.21.4-0.5
Short access day 10 total locomotion1.11.24.9-0.8-0.8-1.0-0.3-0.71.1-1.41.22.20.90.50.9-0.9
Short access total locomotion3.43.57.4-1.7-1.8-1.91.0-1.72.1-2.12.12.72.01.72.00.1
Compulsive drug intake1.31.32.8-0.8-0.9-0.90.9-0.91.2-0.91.51.01.41.71.50.2
One hour access (0.3 mA shock)0.00.00.1-0.1-0.1-0.1-0.1-0.10.10.10.30.30.10.20.2-0.2
One hour access (shock baseline)0.20.20.60.20.20.2-0.50.2-0.40.3-0.6-0.1-0.7-0.8-0.7-0.2
Number of responses in last shaping day0.20.20.50.60.50.5-0.60.5-0.30.30.2-0.00.0-0.00.1-0.7
Context. condit. distance diff. score2.63.14.2-1.7-1.8-1.81.8-1.82.1-1.91.61.41.82.01.81.2
Locomotion velocity, session 10.40.50.9-0.9-0.9-0.90.8-0.80.8-0.90.00.4-0.10.20.30.8
Locomotion distance, session 10.50.72.50.50.40.3-0.80.4-0.20.01.31.00.80.71.0-1.6
Locomotion velocity, session 21.01.23.1-1.4-1.2-1.21.3-1.21.3-1.4-0.50.1-0.4-0.0-0.11.8
Locomotion distance, session 20.60.91.9-0.9-0.9-1.00.5-0.90.7-1.21.11.41.00.91.10.1
Locomotion velocity, session 31.11.32.2-0.9-1.0-1.00.8-1.01.0-1.01.41.31.41.51.50.2
Locomotion distance, session 30.40.40.80.50.60.6-0.40.5-0.30.6-0.8-0.7-0.9-0.8-0.8-0.1
Stereotopy head waving bouts, day 30.50.61.3-0.8-0.8-0.90.5-0.80.5-0.70.71.11.00.60.70.2
Stereotopy head waving duration, day 31.82.23.2-1.5-1.6-1.61.2-1.51.3-1.61.41.81.71.41.50.7
Locomotion velocity, session 70.10.10.40.20.20.3-0.10.2-0.00.1-0.6-0.5-0.6-0.5-0.50.1
Locomotion distance, session 70.10.20.7-0.3-0.3-0.30.4-0.30.9-0.50.20.00.20.40.30.4
Stereotopy head waving bouts, day 70.70.81.8-0.9-0.9-0.90.9-0.91.4-0.90.80.70.91.00.80.6
Stereotopy head waving duration, day 70.00.10.1-0.0-0.0-0.1-0.1-0.10.4-0.20.40.30.30.30.3-0.3
Locomotion velocity, session 81.92.36.4-1.6-1.6-1.51.6-1.62.5-2.00.70.80.81.21.01.4
Locomotion distance, session 85.68.310.7-2.9-3.0-3.02.6-2.93.1-3.32.72.92.93.03.01.6
Degree of sensitization distance2.72.73.9-1.6-1.7-1.71.7-1.72.0-1.81.41.31.61.81.71.1
Degree of sensitization stereotypy0.00.00.10.10.10.1-0.10.10.30.0-0.0-0.2-0.10.1-0.1-0.1
Condit. Reinf. active minus inactive responses0.80.92.40.40.60.6-0.30.5-0.50.5-1.6-1.3-1.4-1.4-1.50.4
Condit. Reinf. active-inactive response ratio0.91.03.8-1.1-0.9-0.91.4-1.01.0-0.8-0.9-0.5-0.4-0.1-0.51.9
Condit. Reinf. active responses0.50.61.20.60.60.6-0.50.6-0.30.5-1.1-0.9-1.1-1.1-1.0-0.1
Condit. Reinf. inactive responses0.91.11.91.31.31.3-1.41.3-0.71.1-0.3-0.6-0.7-0.7-0.5-1.4
Incentive salience index mean1.61.92.91.21.31.3-1.21.3-1.11.2-1.6-1.5-1.6-1.7-1.7-0.5
Condit. Reinf. lever presses1.21.73.11.61.51.5-1.81.6-1.21.2-0.4-0.6-0.8-1.1-0.8-1.7
Time in familiar zone, hab. session 10.00.00.00.00.00.00.00.00.2-0.20.10.0-0.10.10.2-0.0
Time in novel zone, hab. session 10.10.10.3-0.2-0.1-0.10.2-0.1-0.00.1-0.5-0.3-0.2-0.3-0.50.5
Total zone transitions, hab. session 10.00.00.2-0.1-0.1-0.1-0.1-0.00.2-0.4-0.00.2-0.1-0.1-0.1-0.1
Total locomotion distance, hab. session 10.50.72.11.11.01.0-1.21.0-0.50.60.2-0.2-0.4-0.2-0.1-1.4
Locomotion velocity, hab. session 10.20.31.20.70.60.6-0.80.6-0.40.30.40.0-0.10.10.2-1.1
Time in familiar zone, hab. session 21.21.21.6-1.1-1.1-1.21.0-1.11.0-1.31.11.31.11.21.30.6
Time in novel zone, hab. session 21.21.32.70.70.80.8-0.50.8-0.91.0-1.7-1.5-1.4-1.5-1.60.2
Total zone transitions, hab. session 20.81.12.01.11.11.1-1.41.2-0.80.8-0.7-0.5-1.1-1.2-0.8-1.2
Total locomotion distance, hab. session 21.11.52.51.41.41.4-1.61.5-0.81.0-0.8-0.8-1.4-1.3-1.0-1.3
Locomotion velocity, hab. session 21.72.33.91.81.81.7-2.01.8-1.21.4-0.8-0.9-1.4-1.4-1.1-1.8
Novel to familiar place preference ratio0.10.10.3-0.2-0.1-0.10.2-0.10.5-0.2-0.6-0.4-0.5-0.4-0.50.5
Novelty place preference0.20.20.4-0.3-0.3-0.20.3-0.30.6-0.3-0.6-0.3-0.5-0.4-0.50.6
Time in novel zone, NPP test0.20.20.7-0.4-0.3-0.30.5-0.40.5-0.3-0.7-0.4-0.5-0.4-0.50.8
Total zone transitions, NPP test0.30.41.70.50.40.4-0.70.5-0.50.20.90.70.50.40.7-1.3
Total locomotion distance, NPP test0.71.03.31.21.01.0-1.31.1-1.20.90.70.30.10.10.4-1.8
Locomotion velocity, NPP test0.81.23.91.31.21.2-1.51.3-1.31.00.50.2-0.1-0.10.2-2.0
Pavlov. Cond. lever latency0.20.30.8-0.1-0.1-0.00.3-0.1-0.10.1-0.9-0.8-0.7-0.5-0.80.8
Pavlov. Cond. magazine entry latency1.01.22.1-1.0-1.0-1.10.8-1.01.1-1.01.31.31.51.31.30.3
Pavlov. Cond. change in total contacts1.21.32.21.01.11.1-1.01.1-0.51.0-1.3-1.1-1.4-1.5-1.4-0.5
Pavlov. Cond. index score0.81.02.1-0.6-0.7-0.80.4-0.70.7-0.71.41.41.41.21.3-0.2
Pavlov. Cond. latency score0.60.81.8-0.5-0.6-0.70.3-0.60.6-0.71.41.31.31.11.3-0.3
Pavlov. Cond. lever contacts0.20.20.8-0.2-0.2-0.3-0.1-0.20.2-0.40.70.90.60.40.6-0.4
Pavlov. Cond. magazine entry number1.11.42.11.21.21.3-1.11.2-1.51.2-1.1-1.2-1.3-1.2-1.2-0.7
Pavlov. Cond. intertrial magazine entries1.72.05.71.81.71.6-2.01.8-1.21.50.2-0.3-0.4-0.6-0.2-2.4
Pavlov. Cond. lever-magazine prob. diff.1.01.22.4-0.8-0.9-0.90.5-0.80.8-0.91.51.51.61.31.4-0.2
Pavlov. Cond. response bias0.20.30.6-0.4-0.5-0.50.2-0.40.5-0.50.60.80.70.50.6-0.0
Bone: apparent density0.00.00.10.10.10.0-0.10.1-0.20.00.20.10.10.20.3-0.2
Bone surface0.10.20.50.30.30.4-0.20.3-0.00.2-0.6-0.6-0.7-0.5-0.50.0
Bone volume0.20.30.60.50.50.5-0.40.5-0.40.5-0.6-0.7-0.8-0.6-0.6-0.1
Bone: connectivity density0.10.10.3-0.3-0.3-0.30.3-0.40.3-0.40.40.40.40.50.50.2
Bone: cortical apparent density0.50.60.90.60.70.7-0.60.6-0.90.8-0.9-0.8-1.0-1.0-1.0-0.2
Bone: cortical area2.43.64.31.92.02.0-1.92.0-2.12.0-1.7-1.7-2.1-2.0-1.8-1.3
Bone: cortical porosity0.10.10.30.30.30.3-0.30.3-0.50.3-0.0-0.1-0.1-0.1-0.1-0.4
Bone: cortical porosity0.10.10.2-0.1-0.1-0.10.1-0.1-0.2-0.10.40.30.50.40.4-0.2
Bone: cortical thickness1.93.25.41.91.91.9-1.81.9-2.32.1-1.3-1.5-1.7-1.7-1.6-1.4
Bone: cortical thickness0.50.61.40.60.50.5-0.60.5-0.80.81.10.40.80.80.8-1.2
Bone: cortical tissue density0.50.61.00.60.60.7-0.50.6-0.80.8-1.0-0.9-1.0-1.0-1.0-0.1
Bone: elastic displacement0.60.60.9-0.8-0.9-0.90.8-0.80.4-0.60.80.90.90.90.90.5
Bone: elastic work0.20.30.70.60.60.6-0.60.6-0.80.70.0-0.1-0.0-0.2-0.2-0.8
Bone: endosteal estimation0.00.10.20.30.30.4-0.30.30.2-0.1-0.2-0.4-0.3-0.2-0.3-0.2
Bone: endosteal perimeter0.71.52.31.51.51.4-1.51.5-1.11.2-0.6-0.8-1.0-1.0-0.8-1.4
Bone: final force0.20.41.10.20.30.3-0.20.3-0.60.3-1.0-0.7-1.0-1.0-0.90.3
Bone: final moment0.40.61.30.40.50.5-0.40.5-0.80.4-1.1-0.9-1.1-1.1-1.00.1
Bone: marrow area0.00.10.10.30.30.3-0.20.30.3-0.2-0.1-0.3-0.2-0.1-0.2-0.2
Bone: maximum diameter3.05.58.82.12.22.3-1.92.2-2.02.0-2.7-2.7-3.0-2.8-2.8-0.8
Bone: maximum force0.20.40.60.60.60.6-0.60.6-0.60.5-0.7-0.7-0.8-0.8-0.7-0.3
Bone: maximum moment0.40.60.90.80.80.8-0.70.8-0.80.7-0.8-0.8-0.9-1.0-0.9-0.4
Bone: minimum diameter0.00.00.10.10.10.1-0.30.1-0.3-0.10.30.40.1-0.00.2-0.4
Bone: periosteal estimation0.71.41.71.31.31.3-1.21.3-1.01.0-1.0-1.2-1.3-1.2-1.2-0.9
Bone: periosteal perimeter1.93.24.32.12.12.1-2.02.1-1.81.9-1.1-1.4-1.6-1.6-1.4-1.7
Bone: post-yield work0.10.20.30.60.60.6-0.50.5-0.10.4-0.3-0.5-0.5-0.3-0.3-0.4
Bone: stiffness0.00.10.2-0.3-0.3-0.30.2-0.30.3-0.50.10.20.10.10.20.2
Bone: tissue strength1.00.93.0-1.1-1.0-1.01.3-1.11.0-1.2-0.5-0.1-0.10.1-0.11.7
Bone: trabecular number0.00.00.0-0.0-0.0-0.00.1-0.0-0.20.00.10.00.10.20.20.0
Bone: trabecular spacing0.70.91.40.91.01.0-0.80.9-0.81.2-0.9-1.0-1.1-0.9-1.1-0.5
Bone: trabecular thickness0.40.51.50.10.0-0.0-0.20.1-0.1-0.11.20.81.00.91.1-0.8
Bone: trabecular tissue density0.60.91.9-1.0-1.0-1.01.1-1.01.2-1.40.40.50.60.70.61.0
Breakpoint value in progressive ratio session0.91.01.40.90.90.9-0.90.9-1.11.2-1.0-0.9-1.1-1.1-1.1-0.5
Distance traveled before self-admin0.10.10.3-0.2-0.1-0.10.3-0.20.4-0.3-0.5-0.4-0.4-0.3-0.40.6
Distance traveled after self-admin0.30.30.50.60.60.6-0.70.6-0.20.4-0.4-0.3-0.5-0.7-0.5-0.6
Delta time in closed arm before/after self-admin5.25.09.6-1.9-2.1-2.21.4-2.01.9-2.22.83.12.72.62.80.1
Delta time in open arm before/after self-admin5.35.08.31.81.92.0-1.31.9-2.22.1-2.9-2.9-2.8-2.7-2.8-0.0
Diff in mean of infusions in LGA sessions0.10.20.40.20.10.1-0.20.1-0.30.30.60.40.50.50.4-0.6
Extinction: sum of active levers before priming0.30.30.90.20.20.2-0.40.3-0.50.3-0.8-0.3-0.8-1.0-0.8-0.0
Active lever presses in extinction session 60.30.31.10.60.50.5-0.60.5-1.10.90.1-0.0-0.2-0.1-0.1-0.7
Delta distance traveled before/after self-admin0.30.31.20.50.40.3-0.70.4-0.10.30.70.50.60.30.5-1.1
Delta ambulatory time before/after self-admin0.30.30.90.30.20.2-0.50.2-0.10.20.90.60.70.60.6-0.9
Time in closed arm before self-admin0.20.20.60.20.30.3-0.10.3-0.10.6-0.8-0.7-0.7-0.7-0.70.2
Time in closed arm after self-admin1.61.62.6-1.2-1.2-1.30.9-1.21.5-1.21.41.61.51.31.50.3
Time in open arm before self-admin1.71.83.4-0.9-1.0-1.10.8-1.11.4-1.41.81.61.61.81.6-0.1
Time in open arm after self-admin0.10.10.2-0.1-0.1-0.10.0-0.0-0.0-0.2-0.5-0.2-0.4-0.5-0.40.3
Sum of active levers in priming session hrs 5-61.31.32.41.11.21.2-1.11.2-1.51.3-0.9-0.9-1.1-1.1-1.1-0.8
Time to tail flick, vehicle, before self-admin0.40.42.10.60.50.4-1.00.5-0.30.20.50.70.0-0.00.0-1.5
Time to tail flick, vehicle, after self-admin0.50.51.50.90.80.8-1.00.8-0.71.10.0-0.1-0.1-0.3-0.4-1.2
Time to tail flick, test, before self-admin1.71.63.0-1.5-1.5-1.41.7-1.51.5-1.20.50.50.91.00.81.7
Time to tail flick, test, after self-admin3.33.45.21.92.01.9-2.32.0-1.41.9-1.3-1.1-1.9-2.0-1.8-1.9
Delta time to tail flick, vehicle, before/after SA0.10.10.50.40.30.4-0.20.3-0.40.70.2-0.20.30.20.1-0.4
Delta time to tail flick, test, before/after SA3.12.84.21.81.81.7-2.01.8-1.61.6-1.2-1.0-1.8-1.8-1.5-1.7
Ambulatory time before self-admin0.30.30.50.40.50.5-0.40.5-0.20.4-0.7-0.6-0.7-0.7-0.7-0.1
Ambulatory time after self-admin0.30.30.80.60.60.6-0.90.7-0.30.4-0.3-0.1-0.5-0.6-0.5-0.9
Total heroin consumption0.10.10.3-0.1-0.1-0.10.1-0.1-0.30.4-0.4-0.1-0.3-0.2-0.50.3
Area under the delay curve4.75.07.02.62.62.6-2.62.6-2.32.6-1.2-1.8-1.7-1.8-1.8-2.3
Delay disc. indifference point, 0s delay2.02.24.61.81.81.9-1.31.7-1.92.1-0.5-1.6-0.8-0.4-0.8-1.3
Delay disc. indifference point, 16s delay2.22.22.81.51.51.5-1.51.5-1.41.6-1.4-1.4-1.6-1.7-1.7-1.0
Delay disc. indifference point, 2s delay3.84.26.82.62.52.5-2.42.5-2.32.6-0.4-1.4-1.0-0.9-1.0-2.6
Delay disc. indifference point, 24s delay1.81.82.21.41.51.5-1.41.4-1.21.5-1.1-1.3-1.4-1.2-1.4-1.0
Delay disc. indifference point, 4s delay5.45.78.42.92.92.8-2.82.8-2.42.8-1.1-1.9-1.6-1.7-1.7-2.6
Delay disc. indifference point, 8s delay1.71.83.21.61.61.6-1.81.6-1.11.4-0.5-0.7-0.9-1.0-0.9-1.8
Delay discount exponential model param4.54.86.8-2.6-2.6-2.62.6-2.52.1-2.51.21.71.71.71.72.4
Delay discount hyperbolic model param5.15.47.8-2.8-2.8-2.72.7-2.72.3-2.71.21.91.71.71.72.5
Fecal boli incidents, locomotor time 10.20.20.5-0.4-0.4-0.40.2-0.40.3-0.30.50.70.70.40.50.0
Change in fecal boli incidents, locomotor task0.40.41.6-0.6-0.5-0.50.8-0.50.5-0.8-0.7-0.5-0.2-0.3-0.41.3
Time >=10cm from walls, locomotor time 10.30.30.7-0.4-0.5-0.50.6-0.50.0-0.10.70.50.50.90.80.3
Bouts of movement, locomotor time 10.30.41.90.20.30.40.30.2-0.20.3-0.9-1.4-0.5-0.3-0.70.8
Total resting periods, locomotor time 10.20.20.7-0.1-0.1-0.00.5-0.1-0.1-0.1-0.6-0.9-0.2-0.2-0.50.9
Rest time, locomotor task time 10.10.10.2-0.5-0.4-0.40.4-0.40.2-0.30.00.10.10.20.10.5
Distance moved, locomotor task time 10.40.40.70.60.60.6-0.90.7-0.50.4-0.4-0.2-0.6-0.8-0.6-0.7
Vertical activity count, locomotor time 10.10.10.20.40.40.4-0.40.4-0.30.3-0.2-0.2-0.4-0.3-0.3-0.3
Time >=10cm from walls, locomotor time 20.60.71.9-0.3-0.5-0.5-0.0-0.40.5-0.51.31.40.90.91.2-0.7
Bouts of movement, locomotor time 21.92.05.81.91.81.7-2.11.8-1.01.30.0-0.3-0.0-0.8-0.5-2.4
Total resting periods, locomotor time 21.71.84.41.81.71.6-2.01.7-1.01.2-0.2-0.6-0.1-0.8-0.6-2.1
Rest time, locomotor task time 20.30.41.2-0.8-0.7-0.70.9-0.80.4-0.5-0.20.10.20.1-0.01.1
Distance moved, locomotor task time 20.10.20.4-0.2-0.2-0.20.0-0.20.4-0.40.60.60.30.50.6-0.3
Vertical activity count, locomotor time 20.30.30.9-0.2-0.2-0.30.1-0.30.4-0.21.00.70.41.00.8-0.3
Weight adjusted by age0.40.41.00.80.80.8-0.70.7-0.51.0-0.3-0.6-0.6-0.5-0.5-0.7
Seeking ratio, delayed vs. immediate footshock0.40.41.9-0.1-0.2-0.3-0.5-0.0-0.1-0.40.91.40.80.10.7-0.9
Locomotion in novel chamber2.83.49.7-1.1-1.3-1.31.4-1.41.2-1.42.81.72.43.12.70.2
Locomotion in novel chamber post-restriction2.22.64.3-1.2-1.4-1.41.0-1.31.5-1.72.11.91.92.12.10.1
Progressive ratio0.10.10.7-0.3-0.3-0.30.0-0.3-0.1-0.20.60.80.10.40.5-0.3
Food seeking constrained by brief footshock3.13.86.42.32.22.2-2.52.2-2.32.1-0.6-0.8-1.6-1.4-1.1-2.5
Seeking ratio, punishment vs. effort1.61.92.81.71.71.6-1.61.7-1.21.5-0.9-1.2-1.0-1.3-1.1-1.4
Run reversals in cocaine runway, females0.30.31.00.50.40.4-0.50.40.00.40.90.10.50.80.5-1.0
Run reversals in cocaine runway, males0.10.10.3-0.00.00.00.00.00.00.1-0.6-0.3-0.5-0.5-0.50.3
Latency to leave start box in cocaine runway0.60.71.41.01.01.0-0.81.0-1.21.0-0.3-0.7-0.4-0.5-0.3-0.8
Latency to leave start box in cocaine runway, F1.71.83.31.61.61.7-1.31.6-1.81.8-0.6-1.3-0.9-0.7-0.7-1.2
Latency to leave start box in cocaine runway, M0.70.71.4-0.9-0.9-1.00.7-0.90.9-1.20.41.00.70.30.70.6
Cd content in liver0.10.10.4-0.3-0.4-0.40.2-0.3-0.1-0.10.40.60.50.30.40.0
Co content in liver0.10.10.50.00.10.10.10.1-0.00.1-0.7-0.6-0.2-0.5-0.60.4
Cu content in liver0.20.30.9-0.10.00.00.10.0-0.30.1-1.0-0.5-0.9-0.9-0.80.6
Fe content in liver0.50.61.1-1.0-0.9-1.00.8-0.91.1-0.90.30.70.20.40.50.7
K content in liver1.61.63.41.51.41.3-1.71.4-1.71.6-0.0-0.2-0.5-0.7-0.3-1.8
Mg content in liver0.40.40.90.60.60.6-0.60.6-0.90.7-0.5-0.5-0.7-0.6-0.6-0.4
Mn content in liver0.70.82.21.01.00.9-1.31.0-1.01.10.10.1-0.2-0.6-0.2-1.5
Na content in liver2.72.94.61.61.71.8-1.31.6-1.41.7-1.9-2.2-2.1-1.8-2.0-0.6
Rb content in liver1.62.04.31.01.11.2-1.11.2-1.61.3-1.8-1.3-1.7-2.1-1.8-0.3
Se content in liver1.61.92.71.41.41.4-1.41.4-1.51.7-1.3-1.1-1.5-1.6-1.4-1.0
Sr content in liver2.01.82.71.51.51.6-1.11.4-1.41.3-1.2-1.6-1.4-1.2-1.4-0.7
Zn content in liver0.60.71.20.90.90.9-1.11.0-1.10.8-0.3-0.2-0.5-0.8-0.5-1.1