Hub : Genes

Dip2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000056106 0.11 0.07 5.6e-16 0.13 0.13 0.12 0.13 5.3e-14 4.6e-14 9.2e-14 4.4e-14
2 Adipose mRNA stability ENSRNOG00000056106 0.1 0.07 6.1e-11 0.09 0.09 0.09 0.09 4.7e-10 5.9e-10 7.1e-10 8.9e-10
3 BLA gene expression ENSRNOG00000056106 0.13 0.08 5.5e-08 0.1 0.14 0.14 0.12 4.4e-06 5.0e-08 7.8e-08 3.9e-07
4 BLA mRNA stability ENSRNOG00000056106 0.15 0.1 2.7e-07 0.1 0.12 0.12 0.03 3.8e-06 5.7e-07 4.9e-07 1.3e-02
5 Brain mRNA stability ENSRNOG00000056106 0.09 0.06 3.1e-06 0.04 0.06 0.05 0.06 5.1e-05 4.6e-06 8.4e-06 4.2e-06
6 IL gene expression ENSRNOG00000056106 0.22 0.14 2.1e-04 0.16 0.14 0.15 0.1 1.0e-04 4.0e-04 1.5e-04 2.6e-03
7 IL mRNA stability ENSRNOG00000056106 0.18 0.12 5.1e-04 0.07 0.12 0.06 0.01 1.0e-02 7.7e-04 1.7e-02 2.0e-01
8 LHb mRNA stability ENSRNOG00000056106 0.21 0.14 8.2e-04 0.07 0.02 0.07 0.06 1.0e-02 9.3e-02 8.8e-03 1.4e-02
9 Liver mRNA stability ENSRNOG00000056106 0.05 0.03 1.5e-06 0.05 0.05 0.04 0.05 2.7e-06 5.6e-06 1.1e-05 4.0e-06
10 NAcc mRNA stability ENSRNOG00000056106 0.09 0.06 6.3e-07 0.08 0.08 0.08 0.08 1.4e-06 9.9e-07 2.7e-06 1.6e-06
11 OFC mRNA stability ENSRNOG00000056106 0.5 0.17 2.1e-06 0.33 0.25 0.26 0.3 1.6e-08 1.1e-06 5.4e-07 7.9e-08
12 PL gene expression ENSRNOG00000056106 0.15 0.09 9.4e-15 0.22 0.19 0.2 0.21 9.2e-17 3.7e-14 5.5e-15 1.4e-15
13 PL mRNA stability ENSRNOG00000056106 0.27 0.18 6.6e-14 0.17 0.17 0.17 0.16 7.4e-13 3.9e-13 3.8e-13 1.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail4.113.420.1-3.8-3.63.94.03.33.53.44.04.53.62.53.73.5
BMI without tail0.51.03.6-0.7-0.60.70.51.20.61.10.51.50.91.90.70.7
Body weight4.619.422.7-4.7-4.34.54.44.34.44.44.54.84.53.64.44.4
Epididymis fat weight0.30.64.9-0.1-0.1-0.2-0.91.00.10.9-0.10.20.52.20.20.5
Glucose0.20.30.60.70.6-0.6-0.8-0.3-0.6-0.5-0.7-0.0-0.60.2-0.6-0.8
Heart weight0.20.31.2-0.3-0.30.2-0.11.00.40.6-0.00.30.51.10.50.4
Left kidney weight1.13.14.4-1.7-1.51.61.42.11.71.91.61.91.82.11.81.8
Right kidney weight2.15.98.3-2.5-2.32.52.52.52.42.42.32.92.42.12.42.3
Tail length0.10.32.50.10.1-0.4-0.70.6-0.00.5-0.6-0.20.21.6-0.30.1
Length with tail1.55.67.1-2.6-2.42.22.02.52.52.72.11.92.62.52.22.5
Length without tail4.18.911.0-3.3-3.13.13.12.83.22.93.22.73.11.83.13.1
Liver weight, left1.72.74.3-1.7-1.61.40.91.91.71.91.41.41.82.11.51.7
Liver weight, right1.72.85.6-1.7-1.61.40.82.01.62.01.51.71.72.41.41.7
Parametrial fat weight1.01.93.91.51.4-1.6-2.0-0.8-1.4-1.1-1.7-1.3-1.3-0.1-1.5-1.3
Retroperitoneal fat weight0.93.15.52.01.9-2.0-2.3-1.6-1.9-1.4-1.9-1.7-1.7-0.3-1.8-1.6
Intraocular pressure4.15.97.92.72.6-2.6-2.8-2.1-2.5-2.3-2.4-2.2-2.5-1.3-2.6-2.5
Extensor digitorum longus weight4.216.928.0-4.4-4.14.75.33.24.13.34.65.03.90.84.43.8
Soleus weight1.03.03.7-1.8-1.71.71.41.91.71.81.81.61.81.51.81.8
Tibialis anterior weight3.010.222.7-3.3-3.13.94.81.83.12.13.54.32.8-0.53.32.6
Tibia length4.412.518.3-3.6-3.43.12.44.13.44.03.43.23.74.33.33.7
Number of licking bursts1.31.62.91.21.0-1.0-0.7-1.5-1.0-1.4-1.4-1.3-1.2-1.7-1.2-1.4
Food consumed during 24 hour testing period1.92.34.0-1.5-1.41.30.91.71.61.71.31.71.62.01.21.4
Times rat made contact with spout0.10.10.60.10.1-0.1-0.30.3-0.10.2-0.50.20.10.8-0.1-0.0
Mean time between licks in bursts0.20.21.20.20.2-0.20.0-0.6-0.2-0.50.2-1.0-0.3-1.1-0.1-0.0
Mean num. licks in bursts0.91.15.0-0.8-0.60.50.01.50.61.20.71.10.92.20.81.1
Std. dev. time between licks in bursts1.31.62.71.31.3-1.3-1.0-1.3-1.2-1.2-1.4-1.6-1.2-1.0-1.3-1.2
Water consumed over 24 hours0.30.31.90.30.3-0.5-1.00.4-0.20.3-0.7-0.4-0.01.4-0.4-0.1
Indifference point 0 sec5.38.612.13.33.1-3.2-3.2-2.6-3.0-2.6-3.5-2.6-3.0-0.9-3.3-3.2
Indifference point AUC0.30.41.40.60.5-0.3-0.2-0.9-0.4-0.7-0.3-0.6-0.6-1.2-0.4-0.5
Indifference point function ln k4.97.08.6-2.8-2.72.52.32.92.62.72.62.92.72.42.52.6
Indifference point function log k4.97.08.6-2.8-2.72.52.32.92.62.72.62.92.72.42.52.6
Delay discounting total patch changes 0 sec4.97.911.53.12.9-3.1-3.3-2.3-2.9-2.4-3.4-2.5-2.8-0.6-3.2-3.0
Delay discounting total patch changes 12 sec5.57.38.93.02.8-2.7-2.6-2.7-2.7-2.7-3.0-2.6-2.8-1.6-2.8-2.9
Delay discounting total patch changes 18 sec6.78.810.93.23.0-3.1-3.1-2.8-3.0-2.8-3.3-3.2-3.0-1.7-3.0-3.0
Delay discounting total patch changes 24 sec4.05.07.82.52.3-2.3-2.4-2.0-2.2-2.0-2.8-2.3-2.2-1.0-2.3-2.4
Delay discounting total patch changes 6 sec6.29.512.33.53.3-3.2-3.0-3.0-3.1-3.0-3.3-2.9-3.2-1.8-3.2-3.2
Delay discounting time to switch 0 sec2.23.34.02.01.9-1.8-1.4-1.8-2.0-1.9-1.8-1.8-1.9-1.5-1.7-1.9
Delay discounting water rate 0 sec3.25.16.0-2.4-2.32.21.92.52.32.42.12.22.42.12.12.2
Delay discounting water rate 12 sec2.63.95.0-2.2-2.21.81.42.22.12.12.11.62.11.91.82.1
Delay discounting water rate 18 sec0.40.50.8-0.9-0.90.70.70.70.90.70.60.30.70.20.60.7
Delay discounting water rate 24 sec4.25.87.5-2.7-2.62.42.22.42.52.42.62.12.51.62.52.6
Delay discounting water rate 6 sec5.58.010.4-3.1-3.02.82.43.23.03.02.62.53.02.62.72.9
Locomotor activity1.01.52.91.41.5-1.2-0.8-0.9-1.2-1.2-1.7-1.0-1.3-0.4-1.4-1.4
Locomotor testing distance2.74.47.02.52.4-2.2-2.0-1.6-2.1-2.0-2.6-1.7-2.2-0.8-2.3-2.3
Locomotor testing rearing1.82.84.82.12.0-1.9-2.0-0.9-1.7-1.3-2.2-1.0-1.60.2-1.9-1.7
Light reinforcement 10.81.53.11.21.0-1.0-1.0-1.8-1.0-1.3-1.4-1.2-1.2-1.3-1.1-1.3
Light reinforcement 20.00.00.2-0.2-0.20.20.4-0.30.20.00.20.10.1-0.20.20.1
Reaction time number correct1.62.36.1-1.5-1.51.00.22.01.31.81.21.41.52.51.21.5
Reaction time mean minus median5.06.59.02.82.6-2.7-2.9-2.1-2.6-2.4-3.0-2.5-2.5-1.3-2.6-2.6
Reaction time mean minus median AUC3.64.65.72.42.2-2.2-2.3-2.0-2.2-2.1-2.3-1.9-2.2-1.5-2.2-2.2
Reaction time num false alarms1.42.03.51.41.3-1.2-0.9-1.6-1.2-1.6-1.3-1.3-1.5-1.9-1.2-1.5
Reaction time num false alarms AUC1.72.45.21.51.4-1.2-0.8-1.8-1.3-1.8-1.3-1.3-1.6-2.3-1.3-1.7
Reaction time trials correct on left1.62.36.1-1.5-1.51.00.22.01.31.81.21.41.52.51.21.5
Reaction time trials on left1.31.95.7-1.3-1.40.80.11.81.21.71.11.31.32.41.01.4
Reaction time mean0.60.81.51.00.9-1.0-1.1-0.3-1.0-0.7-1.2-0.9-0.8-0.0-0.8-0.8
Reaction time mean AUC0.30.40.90.80.7-0.8-0.9-0.1-0.8-0.4-1.0-0.6-0.60.2-0.6-0.6
Median of all reaction times0.00.10.20.10.1-0.2-0.30.5-0.20.1-0.3-0.10.00.50.0-0.0
Reaction time omissions7.09.412.33.43.2-3.3-3.5-2.7-3.3-2.9-3.3-3.0-3.1-1.7-3.1-3.0
Reaction time false alarm rate2.33.39.71.71.7-1.2-0.5-2.3-1.5-2.2-1.5-1.6-1.8-3.1-1.4-1.9
Reaction time premature initiation rate4.05.36.62.42.5-2.5-2.4-2.2-2.5-2.1-2.6-2.4-2.3-1.1-2.5-2.2
Reaction time premature initiations1.52.24.41.41.5-1.8-2.1-1.0-1.6-1.0-1.7-1.5-1.40.3-1.7-1.3
Std. dev. reaction times4.56.28.12.82.6-2.5-2.6-2.1-2.6-2.4-2.8-2.4-2.5-1.6-2.5-2.5
Reaction time trials completed1.31.95.7-1.3-1.40.80.11.81.21.71.11.31.32.41.01.4
Reaction time trials AUC2.02.86.5-1.7-1.71.20.52.11.52.01.41.61.62.61.31.7
Social response proportion0.20.20.90.30.2-0.4-0.80.3-0.30.2-0.3-0.2-0.11.0-0.4-0.0
Social responses4.55.97.62.72.4-2.3-2.3-2.4-2.3-2.4-2.8-2.2-2.4-1.8-2.7-2.6
Social time0.50.61.8-0.6-0.60.40.11.30.60.90.50.50.71.40.60.7
Conditioned locomotion0.00.00.20.10.1-0.2-0.4-0.0-0.00.0-0.2-0.5-0.10.1-0.1-0.0
Cocaine response after cond. corrected0.10.11.0-0.00.00.10.4-0.4-0.0-0.30.4-0.2-0.1-1.0-0.0-0.0
Cocaine response after cond. not corrected0.20.20.40.50.5-0.4-0.4-0.5-0.5-0.5-0.2-0.5-0.5-0.6-0.5-0.4
Cocaine response before conditioning1.62.04.41.61.5-1.6-2.1-0.7-1.5-1.0-1.9-1.1-1.30.4-1.5-1.4
Saline control response0.20.21.70.20.1-0.2-0.80.60.00.4-0.30.10.11.3-0.10.0
Condit. Reinf. active minus inactive responses1.01.21.9-1.1-1.21.21.01.01.21.01.11.41.10.51.21.0
Condit. Reinf. active-inactive response ratio0.90.91.3-1.0-1.01.00.61.01.00.91.01.21.00.61.11.0
Condit. Reinf. active responses0.10.20.5-0.4-0.40.50.40.40.40.30.30.70.40.20.40.3
Condit. Reinf. inactive responses0.70.91.21.01.0-0.9-0.6-1.0-1.0-1.0-1.1-0.8-1.0-0.6-1.0-1.0
Condit. Reinf. lever presses0.10.10.6-0.00.0-0.1-0.40.4-0.00.3-0.3-0.30.10.80.00.2
Condit. Reinf. lever reinforcers received0.00.00.10.10.00.0-0.10.10.0-0.0-0.20.3-0.00.1-0.1-0.1
Pavlov. Cond. lever latency0.91.22.2-1.2-1.21.21.20.81.20.91.51.31.00.41.11.0
Pavlov. Cond. magazine entry latency0.20.20.90.40.4-0.5-0.5-0.3-0.4-0.3-0.4-0.9-0.3-0.2-0.2-0.2
Pavlov. Cond. change in total contacts0.40.61.5-0.8-0.81.01.20.40.80.50.70.90.7-0.20.70.5
Pavlov. Cond. index score0.50.61.30.90.8-0.8-0.7-0.6-0.8-0.6-1.0-1.1-0.7-0.5-0.7-0.6
Pavlov. Cond. latency score0.40.51.10.80.8-0.7-0.7-0.6-0.7-0.6-0.9-1.1-0.6-0.4-0.7-0.6
Pavlov. Cond. lever contacts0.81.12.01.21.1-1.1-1.2-0.7-1.1-0.8-1.4-1.4-0.9-0.2-1.0-0.9
Pavlov. Cond. magazine entry number0.00.00.1-0.2-0.20.10.2-0.00.10.00.20.30.0-0.0-0.0-0.0
Pavlov. Cond. intertrial magazine entries1.62.14.51.61.5-1.7-2.1-0.5-1.5-0.8-1.9-0.9-1.30.9-1.6-1.4
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.50.5-0.4-0.4-0.4-0.5-0.4-0.6-0.8-0.4-0.4-0.4-0.4
Pavlov. Cond. response bias0.40.61.10.90.8-0.8-1.0-0.5-0.8-0.5-1.0-1.0-0.6-0.1-0.7-0.6
Conditioned reinforcement - actives1.01.01.50.90.9-1.0-0.9-1.0-1.0-1.2-0.8-1.2-1.1-1.1-0.8-1.0
Conditioned reinforcement - inactives1.61.82.61.51.4-1.5-1.6-1.1-1.5-1.3-1.6-1.3-1.4-0.7-1.2-1.4
Conditioned locomotion0.10.10.40.20.1-0.4-0.6-0.2-0.3-0.3-0.5-0.5-0.4-0.0-0.2-0.3
Intermittent access intake day 1-15 change0.20.21.50.40.3-0.6-1.20.1-0.4-0.0-0.2-0.5-0.20.5-0.1-0.1
Intermittent access intake escalation0.20.21.10.0-0.1-0.3-1.00.5-0.10.40.1-0.30.10.90.20.3
Intermittent access intake escalation 20.20.21.30.30.2-0.4-1.10.2-0.30.2-0.3-0.3-0.10.8-0.20.1
Intermitt. access day 1 inactive lever presses0.20.20.90.40.3-0.6-0.9-0.4-0.5-0.3-0.5-0.5-0.50.0-0.5-0.4
Intermitt. access day 15 inactive lever presses0.10.10.60.10.0-0.4-0.80.0-0.2-0.1-0.3-0.5-0.20.2-0.2-0.1
Intermitt. access escalation Index1.21.13.20.80.7-0.7-0.0-1.7-0.9-1.3-0.7-0.7-1.1-1.8-0.9-1.1
Intermittent access day 1 total infusions1.11.31.91.11.0-1.2-1.2-1.0-1.2-1.1-1.1-1.4-1.2-0.8-1.1-1.2
Intermittent access day 15 total infusions1.51.63.61.21.1-1.5-1.9-0.9-1.5-1.1-1.2-1.6-1.3-0.5-1.1-1.2
Intermittent access terminal intake (last 3 days)1.51.63.21.21.1-1.5-1.8-1.1-1.4-1.1-1.2-1.6-1.3-0.6-1.1-1.2
Intermittent access total infusions1.41.52.81.21.1-1.4-1.7-0.9-1.4-1.1-1.2-1.5-1.2-0.6-1.0-1.2
Intermittent access day 1 locomotion1.31.32.21.01.0-1.4-1.5-0.9-1.2-1.0-1.3-1.4-1.2-0.3-1.1-1.1
Intermittent access day 15 total locomotion1.01.03.40.90.7-1.3-1.9-0.4-1.1-0.6-1.3-1.1-0.90.5-0.9-0.9
Intermittent access total locomotion3.43.86.41.91.7-2.2-2.5-1.6-2.1-1.7-2.3-2.2-2.0-0.7-1.9-2.0
Intermittent access standard deviation0.20.20.9-0.1-0.1-0.2-0.90.50.00.50.2-0.20.20.90.20.4
Cocaine induced anxiety1.11.22.9-1.1-1.00.80.61.50.91.30.90.81.11.71.11.1
Post-drug Anxiety5.25.88.1-2.5-2.42.22.12.82.32.62.12.22.52.62.42.4
Baseline Anxiety0.70.71.3-0.9-0.91.01.10.60.90.81.01.10.90.40.60.8
Lifetime Intake2.02.34.01.51.5-1.8-2.0-1.2-1.7-1.3-1.5-1.8-1.5-0.7-1.4-1.5
Incentive Sensitization - Responses0.40.40.9-0.6-0.70.60.30.90.60.80.60.70.71.00.60.5
Incentive Sensitization - Breakpoint0.30.30.7-0.5-0.60.50.30.70.60.60.50.60.60.80.50.4
Progressive ratio test 1 active lever presses7.67.910.22.92.7-3.1-3.2-2.6-3.0-2.7-2.9-3.1-2.9-1.6-2.8-2.8
Progressive ratio test 1 breakpoint6.56.78.62.72.5-2.9-2.9-2.4-2.7-2.5-2.6-2.8-2.6-1.6-2.6-2.6
Progressive ratio test 1 inactive lever presses1.92.13.01.41.3-1.6-1.7-1.5-1.6-1.4-1.3-1.5-1.5-0.9-1.3-1.4
Progressive ratio test 2 active lever presses1.71.83.41.41.2-1.6-1.8-1.0-1.4-1.1-1.4-1.5-1.3-0.3-1.3-1.3
Progressive ratio test 2 breakpoint1.82.03.71.51.3-1.6-1.9-1.1-1.4-1.2-1.6-1.5-1.4-0.3-1.6-1.4
Progressive ratio test 2 inactive lever presses0.91.03.01.10.9-1.3-1.7-0.6-1.1-0.7-0.9-1.2-1.0-0.0-0.8-0.9
Total sessions with >9 infusions1.21.32.31.21.2-1.3-1.5-0.8-1.3-1.1-1.1-1.3-1.2-0.6-0.9-1.2
Short access day 1 total inactive lever presses1.01.11.51.11.0-1.2-1.2-1.1-1.2-1.1-1.0-1.1-1.1-0.6-1.0-1.1
Short access day 10 total inactive lever presses0.10.20.8-0.2-0.20.1-0.40.50.20.50.00.30.40.90.20.4
Short access day 1 total infusions0.50.51.10.80.8-0.9-1.0-0.4-0.8-0.6-0.6-0.8-0.7-0.2-0.6-0.7
Short access day 10 total infusions2.62.94.11.71.7-1.9-1.9-1.6-1.8-1.6-1.5-2.0-1.7-1.2-1.6-1.6
Short access total infusions1.51.73.01.31.3-1.6-1.7-0.9-1.4-1.1-1.3-1.5-1.3-0.5-1.2-1.3
Short access day 1 locomotion0.20.20.30.40.4-0.5-0.5-0.5-0.5-0.5-0.4-0.4-0.5-0.4-0.4-0.6
Short access day 10 total locomotion0.10.10.30.40.4-0.5-0.6-0.1-0.4-0.2-0.5-0.4-0.40.2-0.3-0.4
Short access total locomotion0.50.50.90.60.6-0.8-1.0-0.7-0.7-0.6-0.8-0.8-0.7-0.2-0.6-0.6
Compulsive drug intake1.81.82.9-1.5-1.41.51.71.21.41.21.21.71.30.51.41.2
One hour access (0.3 mA shock)0.10.10.2-0.3-0.30.30.10.50.30.30.10.30.30.30.40.2
One hour access (shock baseline)0.00.10.3-0.1-0.1-0.1-0.40.3-0.00.20.1-0.10.10.50.20.1
Number of responses in last shaping day0.30.30.7-0.6-0.60.60.50.40.50.50.80.40.60.10.80.6
Context. condit. distance diff. score0.30.41.1-0.5-0.60.50.40.70.60.80.50.90.61.10.40.4
Locomotion velocity, session 14.04.35.32.32.2-2.1-2.0-2.0-2.2-2.2-2.2-1.9-2.2-1.5-2.1-2.1
Locomotion distance, session 12.93.74.42.01.9-1.9-1.8-2.0-1.9-2.1-1.6-1.9-2.0-1.9-1.9-2.0
Locomotion velocity, session 20.30.40.60.60.6-0.7-0.8-0.8-0.6-0.5-0.4-0.7-0.6-0.3-0.6-0.5
Locomotion distance, session 23.24.56.02.22.1-2.1-2.0-2.4-2.1-2.2-1.8-2.5-2.2-2.2-2.0-2.1
Locomotion velocity, session 34.35.06.72.52.3-2.5-2.6-1.9-2.3-2.0-2.5-2.5-2.2-1.0-2.2-2.2
Locomotion distance, session 32.52.76.31.81.7-2.0-2.5-0.8-1.7-1.1-1.8-1.7-1.50.5-1.8-1.4
Stereotopy head waving bouts, day 30.40.43.7-0.00.00.20.8-0.6-0.0-0.70.3-0.5-0.3-1.90.2-0.2
Stereotopy head waving duration, day 30.20.31.60.30.3-0.20.1-0.5-0.3-0.6-0.4-0.9-0.4-1.3-0.1-0.2
Locomotion velocity, session 72.73.04.61.91.9-2.1-2.2-1.1-1.9-1.4-2.0-1.9-1.7-0.1-1.8-1.6
Locomotion distance, session 73.74.76.72.42.3-2.5-2.6-1.6-2.3-1.8-2.5-2.3-2.1-0.5-2.3-2.1
Stereotopy head waving bouts, day 70.50.61.8-0.7-0.71.01.30.20.70.20.90.80.5-0.80.90.6
Stereotopy head waving duration, day 71.01.23.1-1.1-1.01.41.80.41.00.51.21.20.9-0.61.20.9
Locomotion velocity, session 80.50.60.80.90.9-0.7-0.7-0.8-0.9-0.8-0.6-0.6-0.8-0.6-0.7-0.7
Locomotion distance, session 81.01.41.91.31.2-1.3-1.4-1.2-1.2-1.1-1.0-1.1-1.2-0.6-1.3-1.3
Degree of sensitization distance0.10.10.90.00.00.20.5-0.4-0.0-0.30.00.1-0.1-1.0-0.0-0.2
Degree of sensitization stereotypy0.70.82.0-0.8-0.81.11.40.30.80.41.01.30.7-0.40.90.7
Condit. Reinf. active minus inactive responses0.10.10.20.30.2-0.2-0.3-0.3-0.2-0.3-0.30.4-0.3-0.1-0.4-0.4
Condit. Reinf. active-inactive response ratio0.30.31.1-0.5-0.50.3-0.00.50.50.60.30.70.51.10.20.3
Condit. Reinf. active responses0.70.91.21.00.9-0.8-0.7-1.0-0.9-1.1-0.9-0.4-1.0-1.0-1.0-1.1
Condit. Reinf. inactive responses3.13.65.72.01.9-1.6-1.2-2.1-1.9-2.2-1.8-1.8-2.0-2.4-1.7-1.9
Incentive salience index mean0.10.10.6-0.1-0.10.20.2-0.10.1-0.00.10.80.0-0.0-0.1-0.1
Condit. Reinf. lever presses0.50.71.7-0.8-0.81.01.30.10.80.40.91.20.7-0.20.70.6
Time in familiar zone, hab. session 10.00.00.2-0.1-0.10.20.30.10.1-0.10.30.40.0-0.40.20.1
Time in novel zone, hab. session 10.00.00.1-0.1-0.20.10.2-0.20.20.0-0.1-0.20.1-0.20.1-0.0
Total zone transitions, hab. session 10.40.53.60.30.20.00.5-1.0-0.2-0.90.1-0.2-0.5-1.9-0.2-0.6
Total locomotion distance, hab. session 10.40.61.80.70.6-0.6-0.4-0.9-0.6-1.0-0.4-0.8-0.8-1.3-0.7-0.8
Locomotion velocity, hab. session 10.30.41.20.50.5-0.5-0.3-0.7-0.5-0.8-0.2-0.6-0.7-1.1-0.6-0.7
Time in familiar zone, hab. session 21.81.82.7-1.3-1.31.31.21.61.31.31.51.61.31.11.31.3
Time in novel zone, hab. session 21.92.02.81.41.3-1.4-1.3-1.7-1.3-1.4-1.5-1.6-1.4-1.3-1.4-1.4
Total zone transitions, hab. session 20.30.40.80.60.5-0.5-0.5-0.8-0.5-0.6-0.4-0.7-0.6-0.9-0.6-0.5
Total locomotion distance, hab. session 20.50.71.10.70.7-0.8-0.9-1.0-0.7-0.8-0.6-1.0-0.8-0.9-0.8-0.7
Locomotion velocity, hab. session 20.30.40.70.50.5-0.6-0.8-0.7-0.5-0.5-0.4-0.9-0.6-0.6-0.7-0.5
Novel to familiar place preference ratio1.21.32.2-1.2-1.21.41.50.51.20.91.31.21.10.11.11.0
Novelty place preference0.70.71.5-0.9-1.01.11.20.21.00.61.01.00.8-0.20.80.6
Time in novel zone, NPP test0.50.51.2-0.7-0.80.91.10.10.80.40.80.80.6-0.40.70.5
Total zone transitions, NPP test2.84.14.82.11.9-1.9-1.6-2.2-1.9-2.2-1.9-2.1-2.1-2.2-2.0-2.1
Total locomotion distance, NPP test3.85.27.12.32.2-2.2-2.1-2.4-2.2-2.4-2.2-2.7-2.3-2.2-2.3-2.2
Locomotion velocity, NPP test2.53.65.01.91.8-1.9-1.8-2.1-1.8-1.9-1.8-2.2-1.9-1.8-1.9-1.8
Pavlov. Cond. lever latency0.20.30.70.50.5-0.7-0.9-0.2-0.5-0.3-0.5-0.8-0.40.1-0.4-0.3
Pavlov. Cond. magazine entry latency1.01.32.2-1.3-1.31.31.50.51.30.91.21.31.10.11.11.0
Pavlov. Cond. change in total contacts1.31.42.7-1.3-1.21.41.60.71.20.91.41.51.10.31.21.0
Pavlov. Cond. index score0.81.02.3-1.1-1.01.21.40.51.00.81.11.50.90.20.90.7
Pavlov. Cond. latency score0.70.81.9-0.9-0.91.11.20.50.90.71.01.40.80.20.80.6
Pavlov. Cond. lever contacts0.10.10.6-0.3-0.30.50.50.20.30.30.40.80.30.20.20.2
Pavlov. Cond. magazine entry number0.40.51.00.80.8-0.8-0.9-0.3-0.8-0.6-0.7-1.0-0.7-0.4-0.6-0.5
Pavlov. Cond. intertrial magazine entries4.85.86.82.62.6-2.5-2.4-2.2-2.5-2.4-2.3-2.3-2.5-1.7-2.5-2.4
Pavlov. Cond. lever-magazine prob. diff.1.11.42.5-1.3-1.21.41.60.71.20.91.31.61.10.31.10.9
Pavlov. Cond. response bias0.30.40.7-0.7-0.70.70.80.20.70.50.60.80.60.20.50.5
Bone: apparent density6.911.514.6-3.6-3.33.12.63.83.33.73.63.03.53.33.43.6
Bone surface9.516.620.4-4.3-4.13.93.14.54.14.44.33.94.24.04.14.2
Bone volume8.714.718.1-4.0-3.83.62.94.33.84.14.03.54.03.63.94.0
Bone: connectivity density3.65.77.6-2.5-2.32.11.62.82.32.62.62.12.52.52.42.5
Bone: cortical apparent density0.60.83.70.60.6-0.40.1-1.1-0.6-1.1-0.3-0.9-0.8-1.9-0.5-0.7
Bone: cortical area5.68.510.5-3.0-2.92.82.33.22.93.12.73.13.03.02.83.0
Bone: cortical porosity0.30.31.8-0.3-0.40.1-0.50.80.40.70.10.20.51.30.20.4
Bone: cortical porosity0.20.21.3-0.0-0.1-0.2-0.70.50.10.5-0.2-0.10.21.1-0.10.1
Bone: cortical thickness1.52.43.3-1.6-1.51.51.21.81.51.71.31.71.61.81.51.6
Bone: cortical thickness0.30.31.10.60.6-0.6-1.0-0.1-0.6-0.2-0.7-0.4-0.40.6-0.7-0.5
Bone: cortical tissue density0.70.94.00.70.8-0.6-0.1-1.2-0.8-1.2-0.4-1.0-0.9-2.0-0.6-0.8
Bone: elastic displacement6.97.811.83.02.9-2.9-2.9-2.6-2.9-2.6-2.9-3.4-2.8-1.8-2.8-2.5
Bone: elastic work0.10.10.90.10.2-0.3-0.40.1-0.20.1-0.1-1.0-0.10.3-0.10.2
Bone: endosteal estimation7.315.718.4-4.2-4.03.72.94.34.04.34.03.74.14.03.84.1
Bone: endosteal perimeter6.513.415.7-3.9-3.73.62.94.03.73.93.33.53.93.53.63.9
Bone: final force10.417.020.6-4.4-4.13.93.04.54.14.54.23.94.34.24.04.3
Bone: final moment11.919.624.0-4.7-4.44.13.24.94.44.84.54.14.64.64.34.6
Bone: marrow area6.814.717.4-4.0-3.93.62.84.23.94.23.93.64.03.93.74.0
Bone: maximum diameter1.62.83.7-1.7-1.61.61.31.91.61.81.31.81.81.91.61.7
Bone: maximum force13.022.626.5-5.2-4.94.64.14.94.95.05.04.45.04.14.75.0
Bone: maximum moment14.725.629.9-5.5-5.24.94.25.35.25.45.34.75.34.55.05.3
Bone: minimum diameter7.614.116.8-4.1-3.93.73.23.83.94.03.83.34.03.23.84.0
Bone: periosteal estimation9.318.922.7-4.6-4.44.13.34.84.44.74.24.24.54.54.24.5
Bone: periosteal perimeter8.714.516.4-4.1-3.93.83.24.03.94.03.63.84.03.43.83.9
Bone: post-yield work7.910.712.6-3.5-3.43.12.63.43.43.53.53.23.42.93.23.4
Bone: stiffness17.127.032.1-5.7-5.45.24.75.25.45.35.54.95.44.15.25.3
Bone: tissue strength1.91.82.6-1.5-1.41.41.51.11.41.21.51.61.30.61.41.2
Bone: trabecular number4.06.28.7-2.5-2.42.11.52.92.42.82.72.12.62.82.42.6
Bone: trabecular spacing1.11.42.01.31.1-1.0-0.9-1.4-1.1-1.3-1.3-0.5-1.2-1.4-1.2-1.4
Bone: trabecular thickness0.50.61.2-0.8-0.80.80.80.70.80.71.10.70.70.20.80.8
Bone: trabecular tissue density0.91.23.2-1.1-1.11.31.8-0.11.10.21.20.30.8-1.61.20.8
Breakpoint value in progressive ratio session0.10.10.60.10.30.10.20.30.30.40.10.50.20.80.30.3
Distance traveled before self-admin2.42.53.41.81.8-1.6-1.1-1.6-1.8-1.6-1.7-1.4-1.7-1.2-1.6-1.6
Distance traveled after self-admin0.60.71.31.11.1-0.9-1.0-0.4-1.0-0.7-0.7-0.9-0.8-0.4-0.8-0.7
Delta time in closed arm before/after self-admin0.10.10.2-0.4-0.40.20.00.20.50.40.40.30.40.50.20.3
Delta time in open arm before/after self-admin3.33.26.22.12.0-2.0-2.5-1.1-1.9-1.4-2.1-1.8-1.6-0.3-1.8-1.6
Diff in mean of infusions in LGA sessions1.41.62.9-1.6-1.51.31.70.71.41.11.01.61.20.81.11.0
Extinction: sum of active levers before priming1.01.02.0-1.1-1.11.11.40.81.00.81.21.40.80.50.90.6
Active lever presses in extinction session 60.10.10.2-0.10.10.20.10.40.30.30.20.00.20.20.30.3
Delta distance traveled before/after self-admin0.50.52.0-0.4-0.50.2-0.51.20.40.90.20.30.71.40.40.7
Delta ambulatory time before/after self-admin0.40.41.9-0.2-0.20.0-0.81.00.30.80.10.10.51.40.30.6
Time in closed arm before self-admin0.70.81.9-0.8-0.61.11.40.70.80.70.81.00.90.21.00.9
Time in closed arm after self-admin0.30.30.9-0.6-0.40.81.00.10.70.40.50.70.6-0.10.60.5
Time in open arm before self-admin0.40.41.7-0.8-0.90.51.3-0.50.4-0.30.80.20.0-1.10.2-0.1
Time in open arm after self-admin0.30.30.70.40.3-0.5-0.2-0.7-0.5-0.7-0.2-0.6-0.6-0.8-0.6-0.5
Sum of active levers in priming session hrs 5-60.50.50.90.80.7-0.7-0.7-0.8-0.6-0.8-0.5-0.9-0.8-1.0-0.5-0.7
Time to tail flick, vehicle, before self-admin0.70.71.41.11.2-0.7-0.4-1.0-0.8-0.9-0.6-0.6-0.9-0.7-0.7-0.9
Time to tail flick, vehicle, after self-admin0.40.51.0-0.5-0.20.81.00.50.80.70.50.90.70.50.70.8
Time to tail flick, test, before self-admin0.20.20.60.40.5-0.30.1-0.5-0.5-0.6-0.1-0.3-0.5-0.8-0.3-0.4
Time to tail flick, test, after self-admin0.80.91.4-0.7-0.60.80.61.00.81.11.10.81.01.21.01.1
Delta time to tail flick, vehicle, before/after SA0.80.81.3-0.9-0.80.80.51.00.81.10.60.91.01.20.71.0
Delta time to tail flick, test, before/after SA0.80.71.2-0.7-0.60.80.40.90.91.10.80.81.01.10.81.0
Ambulatory time before self-admin3.94.15.22.32.2-2.1-1.8-1.9-2.2-2.1-2.2-1.8-2.1-1.5-2.0-2.1
Ambulatory time after self-admin1.71.93.71.71.6-1.5-1.9-0.7-1.5-1.0-1.6-1.4-1.2-0.3-1.2-1.2
Total heroin consumption1.31.63.2-1.3-1.11.00.91.61.11.41.01.51.21.81.11.2
Area under the delay curve1.01.11.5-1.2-1.21.11.21.01.11.01.10.91.10.61.11.0
Delay disc. indifference point, 0s delay1.92.13.0-1.6-1.51.41.21.41.41.41.71.21.50.91.61.5
Delay disc. indifference point, 16s delay1.01.01.3-1.1-1.00.90.91.20.91.01.01.01.00.91.11.0
Delay disc. indifference point, 2s delay1.82.05.2-1.6-1.61.72.30.61.50.91.71.41.2-0.31.21.1
Delay disc. indifference point, 24s delay0.60.51.3-0.8-0.70.81.10.70.90.60.40.60.70.50.60.7
Delay disc. indifference point, 4s delay1.11.11.8-1.1-1.01.10.91.21.11.01.10.91.10.71.31.1
Delay disc. indifference point, 8s delay1.51.52.1-1.4-1.31.11.11.41.21.31.11.01.31.31.21.2
Delay discount exponential model param1.01.11.41.21.1-1.1-1.2-1.0-1.1-1.0-1.0-0.8-1.0-0.5-1.1-1.0
Delay discount hyperbolic model param1.11.21.81.21.2-1.2-1.3-1.0-1.2-0.9-1.1-0.9-1.1-0.4-1.1-1.0
Fecal boli incidents, locomotor time 10.80.92.41.00.9-1.2-1.6-0.5-1.0-0.7-1.2-0.8-0.90.1-0.8-1.0
Change in fecal boli incidents, locomotor task0.20.21.0-0.6-0.50.61.00.10.60.10.40.10.3-0.40.40.4
Time >=10cm from walls, locomotor time 10.30.30.60.50.5-0.7-0.6-0.4-0.5-0.5-0.8-0.8-0.5-0.0-0.5-0.6
Bouts of movement, locomotor time 10.00.00.3-0.0-0.00.10.1-0.30.2-0.2-0.00.0-0.0-0.50.1-0.1
Total resting periods, locomotor time 10.50.51.20.70.6-0.6-0.6-1.0-0.5-0.8-0.7-0.7-0.7-1.1-0.7-0.7
Rest time, locomotor task time 10.70.70.90.80.7-0.8-0.9-0.9-0.7-0.9-0.9-1.0-0.9-0.8-0.8-0.9
Distance moved, locomotor task time 10.00.00.10.10.1-0.00.3-0.1-0.2-0.20.1-0.0-0.1-0.40.1-0.1
Vertical activity count, locomotor time 11.01.11.8-1.0-0.91.01.31.00.90.91.21.20.90.71.20.9
Time >=10cm from walls, locomotor time 20.30.30.70.50.5-0.7-0.8-0.2-0.5-0.5-0.7-0.9-0.5-0.2-0.1-0.5
Bouts of movement, locomotor time 22.93.23.8-2.0-1.91.91.81.61.91.81.81.61.91.41.71.8
Total resting periods, locomotor time 23.33.64.3-2.1-2.02.02.01.72.11.91.91.82.01.31.81.9
Rest time, locomotor task time 20.20.20.40.40.4-0.2-0.2-0.5-0.2-0.4-0.6-0.4-0.4-0.5-0.6-0.4
Distance moved, locomotor task time 20.10.10.30.20.2-0.20.0-0.3-0.4-0.4-0.0-0.2-0.3-0.50.0-0.2
Vertical activity count, locomotor time 20.10.20.4-0.4-0.40.30.30.40.20.30.60.40.30.20.70.3
Weight adjusted by age0.30.42.0-0.5-0.30.71.4-0.40.3-0.00.60.50.3-0.80.30.3
Seeking ratio, delayed vs. immediate footshock0.60.70.9-0.9-1.00.90.80.81.00.80.90.90.90.50.80.9
Locomotion in novel chamber2.73.34.1-1.8-1.81.91.72.01.81.81.92.01.81.32.01.8
Locomotion in novel chamber post-restriction0.50.61.1-0.7-0.80.60.30.70.71.00.90.80.91.10.40.9
Progressive ratio1.11.21.81.11.1-1.1-0.8-1.3-1.0-1.2-1.0-1.3-1.1-1.1-1.2-1.1
Food seeking constrained by brief footshock1.82.23.71.51.5-1.6-1.4-1.4-1.4-1.5-1.5-1.9-1.6-1.0-1.5-1.4
Seeking ratio, punishment vs. effort0.10.10.3-0.4-0.40.30.20.50.40.40.30.30.40.50.30.4
Run reversals in cocaine runway, females0.60.61.5-0.7-0.60.50.01.20.60.90.60.40.81.10.71.0
Run reversals in cocaine runway, males1.01.02.01.11.1-0.7-0.5-1.4-0.8-1.1-0.7-0.8-1.0-1.1-1.2-0.9
Latency to leave start box in cocaine runway0.20.21.5-0.2-0.20.20.6-0.80.0-0.50.2-0.1-0.2-1.2-0.2-0.4
Latency to leave start box in cocaine runway, F2.12.35.91.31.2-1.1-0.4-2.0-1.4-1.9-1.0-1.4-1.6-2.4-1.4-1.6
Latency to leave start box in cocaine runway, M2.22.12.6-1.6-1.61.61.31.31.61.51.31.51.51.01.41.4
Cd content in liver0.40.50.70.80.7-0.7-0.8-0.7-0.7-0.6-0.7-0.8-0.7-0.4-0.7-0.7
Co content in liver0.30.40.60.80.8-0.6-0.6-0.2-0.8-0.5-0.70.2-0.60.3-0.7-0.8
Cu content in liver0.40.52.1-0.5-0.50.4-0.00.90.50.80.60.70.61.40.20.5
Fe content in liver1.01.21.81.21.2-1.1-0.9-1.1-1.2-1.0-1.3-1.2-1.1-0.7-1.1-1.0
K content in liver0.10.10.20.30.3-0.3-0.3-0.1-0.3-0.3-0.4-0.1-0.30.1-0.4-0.3
Mg content in liver0.20.20.40.50.4-0.4-0.4-0.4-0.4-0.5-0.5-0.4-0.5-0.4-0.6-0.6
Mn content in liver0.10.10.3-0.4-0.40.50.50.10.40.30.30.50.30.20.10.2
Na content in liver0.20.20.40.60.6-0.5-0.6-0.0-0.6-0.3-0.5-0.2-0.50.3-0.5-0.4
Rb content in liver1.92.33.31.71.6-1.7-1.8-1.1-1.6-1.3-1.8-1.0-1.6-0.3-1.8-1.6
Se content in liver2.02.53.01.71.7-1.5-1.4-1.7-1.7-1.6-1.7-1.4-1.6-1.2-1.6-1.7
Sr content in liver0.20.21.1-0.1-0.1-0.1-0.60.50.10.50.1-0.00.21.10.20.2
Zn content in liver2.52.73.21.81.6-1.7-1.6-1.7-1.7-1.6-1.8-1.5-1.7-1.0-1.8-1.8