Hub : Genes

Parvb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000055305 0.56 0.07 0.0e+00 0.41 0.38 0.41 0.4 2.3e-23 1.0e-21 1.5e-23 5.0e-23
2 BLA mRNA stability ENSRNOG00000055305 0.19 0.11 6.2e-06 0.07 0.06 0.06 0.05 2.0e-04 3.5e-04 5.9e-04 7.7e-04
3 Brain gene expression ENSRNOG00000055305 0.21 0.1 5.5e-09 0.1 0.11 0.11 0.1 3.4e-09 2.5e-10 5.2e-10 1.0e-09
4 Brain mRNA stability ENSRNOG00000055305 0.17 0.08 3.5e-13 0.15 0.13 0.15 0.15 1.8e-13 4.1e-12 1.5e-13 1.9e-13
5 Eye gene expression ENSRNOG00000055305 0.74 0.15 1.4e-06 0.36 0.31 0.26 0.3 1.8e-06 1.1e-05 6.8e-05 1.4e-05
6 Eye intron excision ratio chr7:115433753:115434167 0.33 0.19 7.5e-03 0.03 0.03 -0.01 0.04 1.0e-01 1.0e-01 5.9e-01 8.6e-02
7 IL gene expression ENSRNOG00000055305 0.47 0.16 1.2e-05 0.24 0.17 0.17 0.23 2.1e-06 5.7e-05 6.1e-05 3.9e-06
8 IL mRNA stability ENSRNOG00000055305 0.41 0.16 5.3e-05 0.02 0.12 0.04 0.06 8.5e-02 1.1e-03 4.5e-02 1.2e-02
9 LHb mRNA stability ENSRNOG00000055305 0.59 0.14 8.7e-07 0.2 0.28 0.25 0.26 1.4e-05 2.2e-07 1.5e-06 6.4e-07
10 OFC gene expression ENSRNOG00000055305 0.39 0.16 7.8e-04 0.17 0.12 0.08 0.11 9.1e-05 9.8e-04 6.6e-03 1.7e-03
11 OFC mRNA stability ENSRNOG00000055305 0.62 0.14 3.3e-06 0.16 0.16 0.13 0.14 1.1e-04 1.0e-04 4.6e-04 4.2e-04
12 PL gene expression ENSRNOG00000055305 0.53 0.13 0.0e+00 0.35 0.23 0.37 0.37 8.6e-28 3.2e-17 3.2e-29 3.7e-29
13 PL mRNA stability ENSRNOG00000055305 0.37 0.14 5.0e-16 0.17 0.09 0.2 0.2 2.6e-13 3.7e-07 8.2e-15 8.3e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.51.76.4-0.6-0.9-0.8-1.6-2.5-1.6-1.0-1.9-0.3-1.0-0.4-1.3-1.3
BMI without tail2.55.26.7-2.3-2.1-2.2-2.3-1.5-2.5-2.1-2.6-2.2-2.1-2.4-2.5-2.5
Body weight0.62.44.3-1.3-1.3-1.4-1.7-1.9-2.0-1.4-2.1-1.0-1.4-0.9-1.7-1.7
Epididymis fat weight0.20.50.9-0.5-0.7-0.5-0.8-1.0-0.9-0.5-0.9-0.4-0.5-0.4-0.7-0.7
Glucose1.92.94.21.41.61.51.91.71.91.72.11.51.71.61.81.8
Heart weight0.20.32.50.50.30.20.2-0.40.20.40.30.90.41.60.30.3
Left kidney weight6.318.045.2-2.4-3.7-3.2-5.3-6.7-5.1-3.6-5.7-1.9-3.6-1.9-4.4-4.4
Right kidney weight5.716.250.2-2.1-3.4-3.0-5.1-7.1-4.9-3.3-5.3-1.2-3.3-1.0-4.2-4.1
Tail length0.10.40.9-0.8-0.4-0.6-0.10.4-0.6-0.4-0.4-0.9-0.4-0.9-0.6-0.7
Length with tail0.00.10.2-0.4-0.3-0.4-0.2-0.1-0.5-0.3-0.3-0.3-0.3-0.2-0.4-0.4
Length without tail0.30.81.71.20.80.90.5-0.80.50.80.41.30.81.20.80.9
Liver weight, left0.10.10.40.50.20.30.1-0.6-0.10.40.00.60.40.40.10.1
Liver weight, right0.10.20.3-0.4-0.5-0.5-0.4-0.1-0.5-0.5-0.5-0.5-0.5-0.4-0.6-0.6
Parametrial fat weight0.00.00.10.20.10.10.1-0.30.10.10.20.00.1-0.10.00.0
Retroperitoneal fat weight0.51.83.2-0.9-1.1-1.0-1.6-1.7-1.6-1.2-1.8-0.8-1.2-1.2-1.4-1.3
Intraocular pressure0.00.10.1-0.3-0.4-0.3-0.30.0-0.2-0.3-0.2-0.1-0.30.3-0.3-0.3
Extensor digitorum longus weight0.52.23.3-1.4-1.3-1.3-1.4-0.7-1.5-1.6-1.6-1.6-1.6-1.8-1.5-1.6
Soleus weight0.20.71.31.11.01.00.5-0.60.50.80.31.10.80.90.70.7
Tibialis anterior weight0.00.10.7-0.1-0.00.0-0.1-0.1-0.1-0.2-0.2-0.4-0.2-0.9-0.2-0.2
Tibia length0.10.10.7-0.00.0-0.2-0.3-0.8-0.4-0.2-0.40.3-0.20.7-0.2-0.2
Number of licking bursts0.10.21.4-0.30.1-0.10.41.20.4-0.00.5-0.3-0.00.00.10.1
Food consumed during 24 hour testing period0.30.42.30.50.40.2-0.2-1.5-0.40.1-0.50.90.11.10.00.1
Times rat made contact with spout0.30.31.40.50.40.3-0.0-1.1-0.10.3-0.00.90.31.20.0-0.0
Mean time between licks in bursts0.81.14.30.30.80.61.42.11.30.71.40.30.70.60.90.9
Mean num. licks in bursts0.50.64.40.60.20.3-0.5-2.1-0.60.2-0.60.90.20.9-0.2-0.2
Std. dev. time between licks in bursts0.40.50.80.60.80.80.90.80.80.70.60.30.7-0.10.60.6
Water consumed over 24 hours0.50.62.9-0.1-0.2-0.5-0.8-1.7-0.9-0.4-0.90.4-0.40.9-0.6-0.5
Indifference point 0 sec0.00.10.20.20.40.20.50.00.40.20.40.20.20.30.20.2
Indifference point AUC0.60.71.00.90.61.00.60.20.91.00.80.91.00.71.01.0
Indifference point function ln k2.12.93.8-1.7-1.6-1.8-1.6-1.2-1.9-1.8-1.8-1.6-1.8-1.3-2.0-1.9
Indifference point function log k2.12.93.8-1.7-1.6-1.8-1.6-1.2-1.9-1.8-1.8-1.6-1.8-1.3-2.0-1.9
Delay discounting total patch changes 0 sec0.10.10.30.20.40.10.50.20.40.10.50.10.10.30.20.2
Delay discounting total patch changes 12 sec0.60.81.31.21.01.10.7-0.20.90.90.61.20.91.00.91.0
Delay discounting total patch changes 18 sec0.71.01.80.80.90.71.00.51.00.91.31.00.91.31.01.1
Delay discounting total patch changes 24 sec0.50.60.9-0.9-0.9-0.9-0.7-0.3-0.8-0.8-0.6-0.9-0.8-0.9-0.8-0.8
Delay discounting total patch changes 6 sec1.11.62.51.21.51.21.40.31.31.21.31.41.21.61.31.3
Delay discounting time to switch 0 sec0.40.61.8-0.8-0.6-0.7-0.6-0.3-0.7-0.8-0.7-1.0-0.8-1.3-0.8-0.8
Delay discounting water rate 0 sec0.10.10.3-0.0-0.4-0.2-0.4-0.6-0.2-0.1-0.30.2-0.10.5-0.2-0.2
Delay discounting water rate 12 sec2.63.95.3-2.2-2.2-2.3-1.9-0.7-2.1-2.2-1.8-2.0-2.2-1.4-2.0-2.1
Delay discounting water rate 18 sec0.00.00.1-0.10.1-0.10.20.30.00.20.20.10.20.30.10.0
Delay discounting water rate 24 sec1.31.72.4-1.2-1.3-1.4-1.4-1.4-1.5-1.2-1.5-1.0-1.2-0.8-1.5-1.5
Delay discounting water rate 6 sec0.00.10.4-0.3-0.3-0.30.00.6-0.1-0.20.1-0.3-0.2-0.1-0.1-0.1
Locomotor activity0.81.31.8-1.0-1.0-1.2-1.3-1.3-1.2-1.2-1.3-0.5-1.2-0.1-1.2-1.2
Locomotor testing distance0.00.00.1-0.2-0.1-0.2-0.10.10.1-0.20.10.0-0.20.3-0.0-0.0
Locomotor testing rearing0.30.50.8-0.7-0.8-0.9-0.8-0.4-0.7-0.8-0.6-0.5-0.8-0.1-0.7-0.8
Light reinforcement 12.85.27.2-2.2-2.7-2.5-2.5-1.5-2.4-2.4-2.1-2.1-2.4-1.7-2.4-2.4
Light reinforcement 24.15.46.1-2.2-2.4-2.3-2.4-1.4-2.4-2.4-2.4-2.4-2.4-2.4-2.5-2.5
Reaction time number correct0.30.42.20.10.40.30.71.50.70.30.6-0.20.3-0.60.50.5
Reaction time mean minus median0.20.20.70.40.50.40.40.30.40.50.40.60.50.80.40.5
Reaction time mean minus median AUC0.00.00.1-0.0-0.10.0-0.3-0.2-0.2-0.1-0.40.1-0.10.2-0.1-0.1
Reaction time num false alarms0.20.21.1-0.20.3-0.20.61.00.50.00.70.10.00.90.30.3
Reaction time num false alarms AUC0.10.20.9-0.10.3-0.10.50.70.50.10.60.30.10.90.30.3
Reaction time trials correct on left0.30.42.20.10.40.30.71.50.70.30.6-0.20.3-0.60.50.5
Reaction time trials on left0.30.42.40.10.40.40.81.60.80.30.6-0.20.3-0.50.60.5
Reaction time mean0.81.11.60.91.31.01.20.81.11.11.10.91.11.01.11.2
Reaction time mean AUC0.91.21.81.01.31.11.30.81.11.11.10.91.10.91.11.2
Median of all reaction times1.31.82.61.21.61.31.50.91.41.31.41.21.31.21.41.5
Reaction time omissions1.41.92.51.21.41.41.51.41.61.51.41.21.51.11.51.5
Reaction time false alarm rate0.10.11.1-0.10.1-0.30.10.00.1-0.10.30.3-0.11.00.00.0
Reaction time premature initiation rate0.50.71.91.40.81.30.3-0.70.60.90.11.10.90.40.80.9
Reaction time premature initiations0.60.81.81.31.01.30.60.00.91.00.41.01.00.11.01.0
Std. dev. reaction times0.20.30.40.40.60.50.50.20.50.50.50.50.50.70.50.6
Reaction time trials completed0.30.42.40.10.40.40.81.60.80.30.6-0.20.3-0.50.60.5
Reaction time trials AUC0.20.31.7-0.00.20.20.51.30.50.20.4-0.30.2-0.60.40.3
Social response proportion0.20.20.5-0.4-0.2-0.4-0.4-0.7-0.5-0.4-0.6-0.3-0.4-0.4-0.7-0.7
Social responses0.20.31.3-0.3-0.5-0.2-0.5-0.2-0.5-0.4-0.6-0.6-0.4-1.1-0.5-0.6
Social time3.14.05.51.72.22.02.42.12.22.12.31.52.11.22.12.0
Conditioned locomotion0.20.21.00.10.20.30.51.00.60.30.60.20.30.40.40.4
Cocaine response after cond. corrected0.30.40.7-0.8-0.7-0.8-0.50.4-0.4-0.6-0.4-0.8-0.6-0.4-0.6-0.7
Cocaine response after cond. not corrected0.80.91.7-1.3-1.0-1.2-0.70.4-0.7-1.0-0.6-1.2-1.0-0.7-1.0-1.0
Cocaine response before conditioning0.10.10.20.00.30.10.40.40.30.20.40.10.20.20.30.3
Saline control response0.40.61.1-1.0-0.7-1.1-0.50.0-0.7-0.9-0.4-0.8-0.9-0.2-0.8-0.9
Condit. Reinf. active minus inactive responses0.60.81.31.10.61.10.5-0.30.61.10.71.11.10.90.91.0
Condit. Reinf. active-inactive response ratio0.30.30.50.60.20.60.2-0.20.30.70.50.70.70.70.60.7
Condit. Reinf. active responses0.20.31.30.80.10.6-0.2-1.1-0.20.6-0.10.80.60.60.30.3
Condit. Reinf. inactive responses0.20.21.50.50.10.3-0.3-1.2-0.50.1-0.50.50.10.2-0.1-0.1
Condit. Reinf. lever presses0.10.10.60.3-0.30.2-0.4-0.8-0.30.0-0.4-0.10.0-0.7-0.2-0.2
Condit. Reinf. lever reinforcers received0.30.41.01.00.30.90.1-0.80.10.80.20.90.80.50.50.6
Pavlov. Cond. lever latency0.10.10.5-0.10.2-0.00.30.70.40.00.30.10.00.60.20.1
Pavlov. Cond. magazine entry latency0.70.91.51.01.01.21.00.50.91.10.90.61.1-0.21.01.0
Pavlov. Cond. change in total contacts0.40.51.01.00.70.90.3-1.00.20.90.30.90.90.40.60.6
Pavlov. Cond. index score0.20.30.60.70.50.80.5-0.10.40.70.40.30.7-0.40.50.5
Pavlov. Cond. latency score0.20.30.60.70.50.80.4-0.10.40.70.40.30.7-0.50.50.5
Pavlov. Cond. lever contacts0.10.10.60.30.10.3-0.2-0.8-0.20.2-0.20.10.2-0.50.00.0
Pavlov. Cond. magazine entry number0.30.30.7-0.7-0.6-0.8-0.50.1-0.4-0.8-0.5-0.4-0.80.4-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.20.31.60.50.30.3-0.0-0.70.10.2-0.00.90.21.30.30.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.40.50.30.60.3-0.20.20.50.30.10.5-0.70.30.3
Pavlov. Cond. response bias0.20.30.70.80.60.80.4-0.40.30.70.40.50.7-0.10.60.6
Conditioned reinforcement - actives1.11.11.41.01.10.91.20.41.21.11.20.91.11.01.11.1
Conditioned reinforcement - inactives0.20.20.40.40.60.40.3-0.10.30.60.40.60.60.60.30.2
Conditioned locomotion1.92.23.1-1.4-1.4-1.6-1.6-1.4-1.7-1.5-1.6-1.3-1.5-1.0-1.7-1.6
Intermittent access intake day 1-15 change0.10.10.40.10.20.10.50.60.40.20.5-0.10.2-0.10.30.3
Intermittent access intake escalation0.10.10.3-0.3-0.2-0.20.20.60.1-0.20.1-0.5-0.2-0.5-0.0-0.0
Intermittent access intake escalation 20.30.30.60.40.40.40.70.40.70.50.80.50.50.60.60.6
Intermitt. access day 1 inactive lever presses0.30.42.0-0.20.0-0.3-0.6-1.4-0.9-0.1-0.80.2-0.10.2-0.6-0.7
Intermitt. access day 15 inactive lever presses0.80.92.01.31.11.10.4-1.20.31.00.11.41.01.10.70.6
Intermitt. access escalation Index0.10.10.3-0.3-0.4-0.3-0.3-0.1-0.3-0.3-0.3-0.4-0.3-0.5-0.4-0.4
Intermittent access day 1 total infusions0.10.10.80.10.20.0-0.1-0.9-0.20.1-0.20.30.10.4-0.1-0.0
Intermittent access day 15 total infusions0.10.10.3-0.4-0.2-0.4-0.2-0.6-0.3-0.3-0.3-0.3-0.3-0.2-0.4-0.3
Intermittent access terminal intake (last 3 days)0.00.00.4-0.1-0.1-0.2-0.2-0.6-0.2-0.1-0.2-0.1-0.1-0.0-0.2-0.1
Intermittent access total infusions0.20.20.6-0.4-0.3-0.5-0.3-0.8-0.5-0.4-0.5-0.3-0.4-0.1-0.5-0.4
Intermittent access day 1 locomotion0.20.30.4-0.6-0.4-0.6-0.5-0.3-0.4-0.6-0.5-0.6-0.6-0.4-0.5-0.4
Intermittent access day 15 total locomotion2.12.22.7-1.5-1.6-1.7-1.5-0.8-1.5-1.6-1.4-1.6-1.6-1.3-1.5-1.5
Intermittent access total locomotion1.51.72.0-1.2-1.3-1.3-1.4-1.1-1.3-1.4-1.4-1.2-1.4-1.1-1.3-1.3
Intermittent access standard deviation0.20.21.1-0.1-0.2-0.2-0.4-1.1-0.4-0.3-0.50.1-0.30.2-0.4-0.3
Cocaine induced anxiety1.31.53.8-0.7-1.0-0.8-1.5-1.9-1.6-1.0-1.7-0.4-1.0-0.5-1.2-1.2
Post-drug Anxiety0.40.41.6-0.2-0.3-0.3-0.8-1.2-1.0-0.3-1.00.1-0.30.1-0.6-0.7
Baseline Anxiety1.51.63.30.91.11.11.51.81.71.11.70.61.10.51.31.2
Lifetime Intake0.30.30.9-0.5-0.4-0.6-0.5-1.0-0.6-0.5-0.6-0.3-0.5-0.1-0.7-0.6
Incentive Sensitization - Responses0.50.53.70.70.20.4-0.5-1.9-0.30.2-0.40.90.20.60.00.1
Incentive Sensitization - Breakpoint0.50.54.30.80.10.4-0.6-2.1-0.30.2-0.50.90.20.6-0.00.0
Progressive ratio test 1 active lever presses0.20.20.40.40.50.50.50.20.60.40.50.40.40.40.40.4
Progressive ratio test 1 breakpoint0.40.40.70.60.70.70.70.50.90.70.70.50.70.50.60.6
Progressive ratio test 1 inactive lever presses0.00.00.10.30.30.3-0.0-0.20.10.2-0.00.30.20.10.0-0.0
Progressive ratio test 2 active lever presses0.50.51.01.00.70.80.3-1.00.40.60.31.00.60.90.50.6
Progressive ratio test 2 breakpoint0.60.71.31.10.80.90.4-1.00.50.80.31.10.80.90.70.8
Progressive ratio test 2 inactive lever presses0.60.61.11.01.01.00.5-0.90.40.90.31.10.90.70.60.6
Total sessions with >9 infusions0.50.50.9-0.9-0.8-0.9-0.6-0.3-0.6-0.8-0.6-0.8-0.8-0.4-0.8-0.8
Short access day 1 total inactive lever presses0.70.83.7-0.4-0.4-0.7-1.1-1.9-1.2-0.5-1.00.1-0.50.5-1.0-0.9
Short access day 10 total inactive lever presses1.82.05.2-1.0-1.2-1.2-1.7-2.3-1.9-1.1-1.6-0.4-1.1-0.1-1.6-1.7
Short access day 1 total infusions0.30.41.6-0.4-0.2-0.6-0.5-1.3-0.7-0.3-0.50.1-0.30.6-0.6-0.7
Short access day 10 total infusions0.00.10.2-0.00.30.10.40.40.30.20.2-0.10.2-0.10.10.1
Short access total infusions0.20.30.8-0.4-0.3-0.5-0.5-0.9-0.6-0.4-0.6-0.2-0.40.1-0.7-0.6
Short access day 1 locomotion0.20.20.5-0.6-0.4-0.7-0.4-0.5-0.5-0.4-0.2-0.4-0.40.0-0.5-0.5
Short access day 10 total locomotion0.10.10.7-0.10.2-0.10.40.80.40.10.4-0.30.1-0.20.20.2
Short access total locomotion0.10.10.2-0.5-0.2-0.5-0.20.1-0.2-0.3-0.2-0.5-0.3-0.3-0.3-0.3
Compulsive drug intake0.90.91.41.11.11.20.8-0.10.81.20.71.21.20.80.80.8
One hour access (0.3 mA shock)0.10.10.1-0.3-0.3-0.3-0.2-0.3-0.2-0.4-0.3-0.4-0.4-0.4-0.3-0.3
One hour access (shock baseline)1.11.22.1-1.3-1.3-1.3-0.80.1-0.8-1.3-0.8-1.5-1.3-1.2-1.0-1.0
Number of responses in last shaping day1.31.31.91.01.21.01.20.71.21.21.41.11.21.11.21.2
Context. condit. distance diff. score1.41.74.5-0.7-1.3-1.1-1.7-2.1-1.5-1.1-1.6-0.3-1.10.2-1.3-1.3
Locomotion velocity, session 10.80.93.0-0.4-0.8-0.7-1.1-1.7-1.3-0.7-1.2-0.3-0.7-0.4-0.9-1.0
Locomotion distance, session 10.20.20.30.50.40.40.50.00.40.50.50.60.50.60.50.5
Locomotion velocity, session 25.36.28.2-2.1-2.4-2.3-2.6-2.3-2.9-2.4-2.8-2.3-2.4-2.4-2.6-2.6
Locomotion distance, session 20.30.40.80.80.70.90.60.00.60.80.60.60.80.10.70.7
Locomotion velocity, session 33.13.54.3-1.7-1.9-1.9-2.1-1.6-2.1-1.9-2.1-1.6-1.9-1.5-2.0-2.0
Locomotion distance, session 30.91.02.1-1.2-1.1-1.0-0.70.4-0.6-1.0-0.7-1.4-1.0-1.4-0.9-0.9
Stereotopy head waving bouts, day 31.11.34.0-0.6-0.9-0.9-1.4-2.0-1.4-0.9-1.4-0.6-0.9-0.7-1.2-1.2
Stereotopy head waving duration, day 32.53.06.9-1.2-1.5-1.6-2.1-2.6-2.2-1.6-2.1-0.8-1.6-0.5-1.9-1.9
Locomotion velocity, session 70.80.91.5-0.8-1.0-0.8-1.1-0.4-0.9-0.9-1.1-1.0-0.9-1.2-0.9-0.9
Locomotion distance, session 70.00.10.30.1-0.00.30.00.40.30.10.1-0.20.1-0.60.20.2
Stereotopy head waving bouts, day 75.05.77.8-2.0-2.3-2.4-2.7-2.6-2.7-2.4-2.8-1.8-2.4-1.4-2.6-2.6
Stereotopy head waving duration, day 73.23.94.9-1.9-2.0-2.1-2.1-1.7-2.2-2.1-2.2-1.6-2.1-1.1-2.2-2.2
Locomotion velocity, session 84.04.814.1-1.2-1.8-1.7-2.7-3.8-2.7-1.8-2.9-0.9-1.8-0.9-2.3-2.2
Locomotion distance, session 81.11.73.4-0.8-1.4-1.1-1.7-1.9-1.4-1.1-1.6-0.7-1.1-0.7-1.3-1.3
Degree of sensitization distance0.70.71.61.10.91.00.3-0.90.40.90.21.30.91.00.70.7
Degree of sensitization stereotypy3.13.44.2-1.7-1.9-2.0-2.0-1.7-2.0-1.9-2.0-1.4-1.9-0.9-2.0-2.0
Condit. Reinf. active minus inactive responses1.82.03.41.21.31.51.61.81.61.41.61.01.40.61.61.5
Condit. Reinf. active-inactive response ratio1.51.62.21.01.11.11.31.51.31.21.41.21.21.41.31.3
Condit. Reinf. active responses1.11.44.40.70.91.11.42.11.31.01.40.31.0-0.21.31.2
Condit. Reinf. inactive responses0.20.21.3-0.00.10.30.40.90.30.10.3-0.50.1-1.20.30.2
Incentive salience index mean1.61.93.81.11.21.41.52.01.61.31.50.81.30.31.51.5
Condit. Reinf. lever presses0.40.51.50.40.50.70.71.20.80.60.7-0.00.6-0.70.70.7
Time in familiar zone, hab. session 10.70.61.2-0.5-0.7-0.7-0.9-1.1-1.0-0.7-0.9-0.5-0.7-0.5-0.8-0.8
Time in novel zone, hab. session 10.10.10.8-0.10.1-0.10.30.60.40.10.40.30.10.90.20.2
Total zone transitions, hab. session 11.01.42.20.91.11.11.51.41.41.11.50.71.10.51.31.3
Total locomotion distance, hab. session 10.71.02.5-1.0-0.9-0.9-0.8-0.3-0.8-1.0-0.9-1.3-1.0-1.6-1.0-1.0
Locomotion velocity, hab. session 10.81.13.2-1.0-1.0-0.9-0.9-0.4-0.9-1.0-1.0-1.3-1.0-1.8-1.0-1.0
Time in familiar zone, hab. session 20.50.51.1-0.7-0.7-0.7-0.60.1-0.7-0.7-0.6-0.9-0.7-1.0-0.6-0.7
Time in novel zone, hab. session 20.50.52.40.50.60.40.6-0.10.60.60.71.00.61.60.50.6
Total zone transitions, hab. session 20.10.10.80.50.20.4-0.2-0.9-0.10.3-0.20.40.30.00.10.1
Total locomotion distance, hab. session 20.40.51.2-0.5-0.7-0.5-0.8-0.7-0.7-0.6-0.8-0.7-0.6-1.1-0.7-0.7
Locomotion velocity, hab. session 20.20.31.1-0.3-0.5-0.3-0.6-0.6-0.5-0.4-0.6-0.6-0.4-1.1-0.5-0.5
Novel to familiar place preference ratio0.20.20.4-0.4-0.4-0.6-0.4-0.6-0.5-0.5-0.40.0-0.50.6-0.5-0.5
Novelty place preference0.50.50.8-0.7-0.7-0.9-0.7-0.9-0.8-0.7-0.7-0.2-0.70.5-0.8-0.8
Time in novel zone, NPP test0.60.71.0-0.8-0.8-1.0-0.8-1.0-0.9-0.8-0.8-0.2-0.80.7-0.9-0.9
Total zone transitions, NPP test0.30.40.50.70.60.70.50.00.60.70.60.60.70.30.70.7
Total locomotion distance, NPP test0.91.22.2-1.0-1.1-1.0-1.2-0.8-1.1-1.1-1.1-1.2-1.1-1.5-1.1-1.1
Locomotion velocity, NPP test0.60.93.1-0.9-0.9-0.7-0.8-0.3-0.8-0.9-0.9-1.2-0.9-1.8-0.9-0.9
Pavlov. Cond. lever latency0.50.71.8-0.4-0.6-0.7-1.1-1.4-0.9-0.7-1.1-0.2-0.70.2-0.9-0.9
Pavlov. Cond. magazine entry latency3.64.66.41.82.02.02.42.22.52.12.51.72.11.52.32.3
Pavlov. Cond. change in total contacts3.13.35.11.51.61.72.12.12.01.82.31.41.81.32.01.9
Pavlov. Cond. index score2.33.04.31.51.61.72.01.82.01.72.11.31.71.11.91.9
Pavlov. Cond. latency score1.31.72.61.01.21.21.51.51.51.31.60.91.30.81.41.4
Pavlov. Cond. lever contacts0.70.82.30.50.70.71.21.51.10.81.30.20.8-0.11.01.0
Pavlov. Cond. magazine entry number3.74.66.3-1.8-2.0-2.1-2.4-2.3-2.5-2.1-2.5-1.6-2.1-1.5-2.3-2.3
Pavlov. Cond. intertrial magazine entries0.00.00.10.00.20.10.30.30.10.10.30.00.10.00.20.1
Pavlov. Cond. lever-magazine prob. diff.2.53.24.71.41.61.72.12.02.11.82.21.21.81.01.91.9
Pavlov. Cond. response bias3.03.75.91.51.81.82.32.42.31.92.41.21.91.02.12.1
Bone: apparent density0.20.30.70.10.50.20.70.60.50.40.80.40.40.70.50.5
Bone surface0.10.10.50.10.30.10.40.10.20.30.50.40.30.70.30.3
Bone volume0.00.10.4-0.10.2-0.10.30.20.10.20.40.20.20.70.20.2
Bone: connectivity density0.10.10.2-0.00.2-0.00.40.50.20.20.50.10.20.40.20.2
Bone: cortical apparent density1.62.12.61.51.41.61.41.01.51.61.61.31.60.91.61.6
Bone: cortical area0.20.30.4-0.5-0.5-0.6-0.5-0.6-0.6-0.5-0.6-0.1-0.50.4-0.6-0.6
Bone: cortical porosity0.10.10.2-0.3-0.2-0.4-0.3-0.1-0.3-0.3-0.4-0.2-0.3-0.1-0.4-0.5
Bone: cortical porosity0.40.40.7-0.6-0.5-0.7-0.6-0.4-0.7-0.7-0.7-0.5-0.7-0.2-0.8-0.8
Bone: cortical thickness1.21.92.31.41.51.41.40.61.41.51.31.51.51.51.41.4
Bone: cortical thickness0.60.71.50.90.80.80.60.00.70.90.71.10.91.20.90.9
Bone: cortical tissue density1.41.82.41.41.31.51.30.81.41.51.41.21.50.81.51.5
Bone: elastic displacement1.82.03.1-1.3-1.3-1.5-1.5-1.3-1.8-1.4-1.6-1.1-1.4-0.9-1.6-1.6
Bone: elastic work4.15.37.7-1.9-2.1-2.2-2.6-2.7-2.8-2.3-2.7-1.5-2.3-1.2-2.5-2.5
Bone: endosteal estimation3.98.511.1-2.6-3.0-3.0-3.2-2.7-3.3-2.9-3.3-2.3-2.9-1.7-3.2-3.2
Bone: endosteal perimeter4.79.811.5-3.1-3.4-3.3-3.3-2.0-3.4-3.3-3.3-2.9-3.3-2.3-3.4-3.4
Bone: final force0.40.61.70.90.70.70.2-1.00.20.70.11.20.71.30.50.5
Bone: final moment0.40.62.00.90.70.70.1-1.30.10.7-0.01.30.71.40.40.4
Bone: marrow area3.98.311.0-2.6-3.0-2.9-3.2-2.8-3.3-2.9-3.3-2.2-2.9-1.7-3.2-3.2
Bone: maximum diameter3.46.28.8-2.1-2.5-2.5-2.8-2.7-3.0-2.5-2.9-1.6-2.5-1.0-2.7-2.8
Bone: maximum force0.20.42.60.40.10.0-0.4-1.6-0.40.1-0.60.80.11.2-0.2-0.2
Bone: maximum moment0.30.63.50.40.10.0-0.6-1.9-0.50.1-0.70.90.11.3-0.3-0.2
Bone: minimum diameter2.54.65.9-2.3-2.3-2.4-2.1-1.0-2.2-2.3-2.1-2.2-2.3-1.7-2.3-2.3
Bone: periosteal estimation2.44.96.5-2.0-2.2-2.3-2.4-2.1-2.6-2.2-2.5-1.6-2.2-1.0-2.5-2.5
Bone: periosteal perimeter3.35.57.0-2.4-2.5-2.6-2.4-1.5-2.5-2.5-2.5-2.1-2.5-1.3-2.6-2.6
Bone: post-yield work2.33.26.91.91.81.71.40.11.61.91.42.31.92.61.71.7
Bone: stiffness1.32.06.01.41.41.21.20.21.31.31.21.91.32.41.31.3
Bone: tissue strength0.10.10.50.50.40.30.1-0.40.00.30.10.60.30.70.20.2
Bone: trabecular number0.10.21.2-0.40.0-0.40.51.10.4-0.00.7-0.1-0.00.50.20.1
Bone: trabecular spacing0.60.72.2-0.1-0.4-0.2-1.1-1.5-1.0-0.6-1.4-0.4-0.6-1.0-0.7-0.7
Bone: trabecular thickness0.00.00.1-0.3-0.2-0.20.00.20.0-0.10.2-0.3-0.1-0.3-0.1-0.1
Bone: trabecular tissue density0.60.91.11.01.01.01.00.41.11.01.00.91.00.61.01.0
Breakpoint value in progressive ratio session0.40.40.6-0.5-0.7-0.5-0.7-0.5-0.8-0.6-0.7-0.6-0.6-0.7-0.7-0.7
Distance traveled before self-admin0.40.50.80.90.60.80.6-0.00.80.70.50.80.70.60.70.8
Distance traveled after self-admin0.20.20.8-0.2-0.4-0.4-0.7-0.9-0.6-0.1-0.5-0.1-0.1-0.1-0.6-0.7
Delta time in closed arm before/after self-admin1.21.22.11.41.21.20.9-0.20.91.11.01.51.11.40.90.8
Delta time in open arm before/after self-admin4.54.35.4-2.2-2.3-2.3-2.2-0.7-2.1-2.2-2.0-2.2-2.2-1.9-2.1-2.0
Diff in mean of infusions in LGA sessions5.76.37.52.72.72.72.40.82.52.72.52.72.72.52.62.6
Extinction: sum of active levers before priming0.30.30.60.70.70.80.30.30.40.70.20.50.70.00.60.6
Active lever presses in extinction session 60.10.10.40.60.20.5-0.0-0.30.10.2-0.10.60.20.50.30.2
Delta distance traveled before/after self-admin2.32.54.2-1.5-1.5-1.7-1.9-1.5-2.0-1.3-1.6-1.1-1.3-0.7-1.9-2.0
Delta ambulatory time before/after self-admin1.51.62.7-1.1-1.2-1.4-1.5-1.3-1.6-1.2-1.2-0.7-1.2-0.1-1.6-1.6
Time in closed arm before self-admin0.60.62.60.30.60.51.11.61.00.60.9-0.10.6-0.30.80.7
Time in closed arm after self-admin0.10.10.40.20.30.10.50.40.40.20.60.20.20.40.20.2
Time in open arm before self-admin0.00.00.10.00.20.20.30.30.20.10.20.10.1-0.00.0-0.1
Time in open arm after self-admin3.23.54.8-1.9-2.0-1.7-2.0-0.7-1.9-1.9-2.0-2.0-1.9-2.2-1.8-1.8
Sum of active levers in priming session hrs 5-60.20.20.4-0.2-0.5-0.3-0.6-0.6-0.5-0.4-0.6-0.3-0.4-0.5-0.4-0.4
Time to tail flick, vehicle, before self-admin0.00.00.10.30.20.1-0.1-0.20.0-0.1-0.10.2-0.10.10.10.2
Time to tail flick, vehicle, after self-admin0.30.30.5-0.6-0.7-0.5-0.30.6-0.3-0.6-0.3-0.7-0.6-0.7-0.4-0.4
Time to tail flick, test, before self-admin0.20.20.5-0.3-0.5-0.4-0.3-0.2-0.4-0.7-0.3-0.3-0.7-0.2-0.4-0.5
Time to tail flick, test, after self-admin0.60.61.40.50.70.70.91.21.00.61.10.40.60.30.90.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.4-0.10.30.0-0.50.10.10.00.40.10.40.10.2
Delta time to tail flick, test, before/after SA0.70.71.00.60.90.70.90.91.01.01.00.41.00.30.80.8
Ambulatory time before self-admin0.60.61.01.00.80.90.6-0.20.60.90.50.90.90.70.70.7
Ambulatory time after self-admin0.10.10.40.10.0-0.1-0.3-0.6-0.30.2-0.10.20.20.4-0.3-0.4
Total heroin consumption0.10.20.60.60.20.5-0.1-0.70.0-0.0-0.10.6-0.00.50.30.4
Area under the delay curve2.22.43.51.31.81.71.91.71.71.61.81.21.60.91.41.2
Delay disc. indifference point, 0s delay0.30.40.6-0.7-0.6-0.6-0.6-0.0-0.8-0.5-0.6-0.6-0.5-0.5-0.6-0.7
Delay disc. indifference point, 16s delay1.71.72.91.11.41.41.61.71.61.41.50.61.40.11.11.0
Delay disc. indifference point, 2s delay0.80.91.20.81.01.01.11.01.00.91.10.90.90.80.90.7
Delay disc. indifference point, 24s delay1.11.01.71.11.31.31.20.81.11.10.90.81.10.20.90.7
Delay disc. indifference point, 4s delay1.21.32.31.11.21.21.10.30.91.21.21.51.21.50.80.6
Delay disc. indifference point, 8s delay2.22.23.51.21.71.51.91.81.81.51.70.91.50.51.41.3
Delay discount exponential model param2.52.63.7-1.5-1.9-1.8-1.9-1.6-1.8-1.7-1.8-1.4-1.7-1.0-1.4-1.2
Delay discount hyperbolic model param1.82.02.8-1.3-1.6-1.5-1.7-1.4-1.5-1.5-1.6-1.2-1.5-1.0-1.2-1.0
Fecal boli incidents, locomotor time 10.00.10.20.0-0.00.2-0.3-0.3-0.2-0.1-0.3-0.1-0.1-0.5-0.2-0.3
Change in fecal boli incidents, locomotor task0.30.30.7-0.8-0.7-0.8-0.40.2-0.6-0.5-0.4-0.6-0.5-0.1-0.6-0.6
Time >=10cm from walls, locomotor time 10.30.40.6-0.5-0.3-0.5-0.6-0.6-0.7-0.8-0.6-0.4-0.8-0.5-0.6-0.6
Bouts of movement, locomotor time 10.30.30.60.80.50.70.40.10.70.60.40.50.60.20.50.6
Total resting periods, locomotor time 10.50.61.01.00.71.00.70.30.90.80.70.70.80.40.80.8
Rest time, locomotor task time 10.20.20.70.1-0.30.0-0.6-0.5-0.2-0.4-0.6-0.3-0.4-0.8-0.3-0.3
Distance moved, locomotor task time 10.00.00.3-0.2-0.1-0.20.1-0.2-0.2-0.00.10.2-0.00.5-0.2-0.2
Vertical activity count, locomotor time 10.20.21.00.10.50.20.60.10.20.30.60.60.31.00.20.1
Time >=10cm from walls, locomotor time 20.30.40.7-0.8-0.3-0.6-0.20.3-0.4-0.7-0.3-0.8-0.7-0.8-0.6-0.7
Bouts of movement, locomotor time 21.61.72.81.21.71.41.31.31.41.41.11.01.40.71.41.4
Total resting periods, locomotor time 22.22.43.71.51.91.61.51.31.61.71.31.31.70.91.71.7
Rest time, locomotor task time 20.20.20.40.40.60.50.40.40.60.40.40.10.4-0.10.40.4
Distance moved, locomotor task time 21.41.62.3-1.3-1.4-1.3-1.3-0.9-1.5-1.3-1.3-1.0-1.3-0.8-1.4-1.4
Vertical activity count, locomotor time 21.92.12.7-1.3-1.6-1.4-1.5-1.1-1.6-1.6-1.5-1.1-1.6-1.0-1.5-1.5
Weight adjusted by age1.21.31.7-1.0-1.2-1.0-1.2-0.7-1.2-1.1-1.3-1.1-1.1-1.3-1.3-1.3
Seeking ratio, delayed vs. immediate footshock0.30.42.10.00.40.10.81.50.80.30.8-0.40.3-0.50.40.5
Locomotion in novel chamber3.23.96.3-2.5-2.2-2.3-1.40.3-1.7-2.2-1.2-2.5-2.2-2.1-2.0-2.0
Locomotion in novel chamber post-restriction0.10.10.8-0.3-0.2-0.10.20.90.1-0.40.2-0.5-0.4-0.60.0-0.1
Progressive ratio1.41.72.11.31.51.41.40.61.41.31.31.31.31.21.31.3
Food seeking constrained by brief footshock0.30.41.3-0.4-0.5-0.7-0.7-1.2-0.8-0.6-0.6-0.2-0.60.0-0.5-0.5
Seeking ratio, punishment vs. effort0.70.91.4-0.7-1.0-1.0-1.2-1.1-1.2-0.9-1.1-0.7-0.9-0.6-0.9-0.8
Run reversals in cocaine runway, females1.11.02.4-1.5-1.0-1.1-0.21.2-0.4-1.0-0.1-1.5-1.0-1.4-0.7-0.6
Run reversals in cocaine runway, males0.50.50.8-0.7-0.9-0.8-0.8-0.3-0.8-0.8-0.7-0.4-0.8-0.0-0.6-0.6
Latency to leave start box in cocaine runway1.11.22.6-0.8-1.1-0.9-1.4-1.6-1.3-0.8-1.3-0.7-0.8-0.7-1.2-1.1
Latency to leave start box in cocaine runway, F0.10.10.80.0-0.3-0.2-0.6-0.9-0.40.0-0.4-0.10.0-0.1-0.2-0.1
Latency to leave start box in cocaine runway, M1.11.02.2-0.7-0.8-0.8-1.1-1.5-1.3-0.9-1.2-0.5-0.9-0.5-1.1-1.2
Cd content in liver0.80.93.80.70.90.70.90.50.70.80.91.20.81.90.70.6
Co content in liver0.91.11.8-0.9-1.2-1.2-1.3-1.3-1.1-1.1-1.1-0.7-1.1-0.4-1.0-0.8
Cu content in liver0.80.96.3-0.40.10.21.12.51.00.31.3-0.70.3-0.80.60.4
Fe content in liver0.30.30.6-0.6-0.7-0.8-0.6-0.6-0.6-0.4-0.3-0.2-0.40.4-0.7-0.8
K content in liver0.10.10.60.40.20.5-0.1-0.8-0.00.3-0.10.20.3-0.40.10.1
Mg content in liver0.20.20.40.50.50.60.3-0.30.30.50.20.30.5-0.30.30.3
Mn content in liver0.91.01.4-0.7-0.9-0.8-1.2-1.1-1.0-0.9-1.1-0.9-0.9-1.1-1.1-1.1
Na content in liver3.53.85.31.62.01.92.32.12.31.92.21.51.91.32.02.0
Rb content in liver0.40.50.80.60.60.70.70.50.70.80.90.80.80.90.70.7
Se content in liver0.10.20.9-0.5-0.3-0.3-0.10.1-0.3-0.4-0.1-0.6-0.4-1.0-0.2-0.2
Sr content in liver0.20.10.60.10.20.20.40.80.50.20.5-0.10.2-0.20.40.4
Zn content in liver0.10.10.8-0.1-0.00.00.40.90.50.20.6-0.20.2-0.10.30.3