Hub : Genes

Ptprb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000085231 0.19 0.1 0.0e+00 0.17 0.16 0.16 0.16 4.8e-18 2.5e-17 2.2e-17 3.1e-17
2 Adipose alternative polyA ENSRNOT00000085334 0.14 0.08 1.7e-15 0.12 0.12 0.14 0.12 2.2e-13 1.0e-13 4.1e-15 1.9e-13
3 Adipose alternative polyA ENSRNOT00000094476 0.03 0.03 2.0e-03 0.02 0.01 0.02 0.02 5.2e-03 1.1e-02 5.3e-03 4.6e-03
4 Adipose alternative polyA ENSRNOT00000085231 0.05 0.03 5.5e-05 0.02 0.02 0.02 0.03 1.8e-03 1.2e-03 1.0e-03 7.3e-04
5 Adipose alternative polyA ENSRNOT00000094476 0.04 0.03 6.8e-05 0.02 0.02 0.02 0.03 1.4e-03 1.1e-03 9.8e-04 3.8e-04
6 Adipose alternative TSS ENSRNOT00000094476 0.13 0.08 4.0e-08 0.08 0.08 0.07 0.07 4.3e-09 7.9e-09 2.1e-08 1.1e-08
7 Adipose alternative TSS ENSRNOT00000119174 0.13 0.08 3.4e-08 0.08 0.08 0.07 0.08 4.2e-09 7.9e-09 5.6e-08 8.7e-09
8 Adipose gene expression ENSRNOG00000055293 0.11 0.07 1.1e-09 0.06 0.07 0.06 0.06 2.5e-07 1.7e-08 1.8e-07 1.8e-07
9 Adipose isoform ratio ENSRNOT00000085334 0.09 0.06 1.9e-09 0.1 0.07 0.13 0.1 1.2e-10 1.9e-08 5.7e-14 3.0e-11
10 Adipose isoform ratio ENSRNOT00000119174 0.13 0.08 9.0e-11 0.07 0.09 0.14 0.11 4.2e-08 1.6e-10 4.6e-15 2.4e-12
11 Adipose intron excision ratio chr7:51939417:51954068 0.04 0.03 4.5e-03 0 0.01 0 0 2.3e-01 5.7e-02 1.3e-01 9.3e-02
12 Adipose mRNA stability ENSRNOG00000055293 0.04 0.03 1.7e-04 0.03 0.02 0.01 0.03 7.2e-04 8.9e-04 1.8e-02 8.3e-04
13 LHb mRNA stability ENSRNOG00000055293 0.18 0.13 3.4e-03 0.09 0.09 0.1 0.09 4.5e-03 3.7e-03 1.9e-03 3.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.03.29.4-2.12.22.0-2.01.90.0-0.0-2.33.1-0.60.11.7-1.7
BMI without tail3.98.117.0-3.43.63.2-3.23.21.0-1.2-3.54.1-1.80.32.3-3.1
Body weight0.83.69.0-2.32.22.2-2.22.2-0.50.5-2.33.0-0.0-0.42.0-1.6
Epididymis fat weight0.92.14.4-1.81.52.0-1.81.80.2-0.1-2.11.1-0.00.81.3-1.6
Glucose0.10.20.40.6-0.4-0.50.6-0.60.3-0.30.3-0.2-0.30.4-0.50.2
Heart weight1.01.410.6-0.30.51.0-0.70.80.9-0.9-0.9-3.3-0.2-0.21.1-0.9
Left kidney weight0.30.72.4-0.80.71.1-0.91.0-0.0-0.1-1.1-1.60.2-0.11.0-0.8
Right kidney weight0.51.43.0-1.31.21.6-1.41.40.6-0.7-1.7-0.6-0.60.31.2-1.6
Tail length0.72.24.2-2.01.81.9-2.01.9-0.50.4-1.61.40.2-0.91.8-1.1
Length with tail0.31.02.0-1.00.71.0-1.01.0-1.41.3-0.70.31.3-0.91.4-0.0
Length without tail0.40.92.20.7-0.9-0.60.6-0.6-1.21.40.8-0.91.5-0.70.11.2
Liver weight, left0.30.51.10.6-0.8-0.50.7-0.7-0.80.70.3-0.40.81.0-0.70.6
Liver weight, right0.61.02.90.6-0.8-0.70.6-0.6-1.71.61.0-0.21.5-0.7-0.11.4
Parametrial fat weight0.30.51.2-1.10.50.9-0.90.9-0.80.5-0.80.80.40.50.4-0.4
Retroperitoneal fat weight0.20.61.5-0.70.71.1-0.80.9-0.1-0.1-1.2-0.70.31.10.5-0.9
Intraocular pressure3.24.58.1-2.82.52.8-2.82.80.3-0.2-2.50.4-0.1-1.62.8-2.0
Extensor digitorum longus weight1.66.311.3-2.83.12.9-2.82.81.5-1.6-3.42.1-1.90.12.4-3.2
Soleus weight0.10.20.4-0.40.30.6-0.50.50.4-0.4-0.6-0.6-0.20.20.3-0.6
Tibialis anterior weight2.07.013.9-2.52.92.8-2.62.62.7-2.8-3.50.8-2.81.01.9-3.7
Tibia length0.10.41.70.8-0.5-0.30.6-0.6-0.60.50.2-1.30.80.3-0.00.4
Number of licking bursts0.30.30.6-0.40.50.5-0.40.40.8-0.8-0.7-0.4-0.60.50.2-0.8
Food consumed during 24 hour testing period1.11.42.6-1.41.41.5-1.41.40.6-0.6-1.60.4-0.60.11.2-1.5
Times rat made contact with spout0.20.20.70.00.10.1-0.00.10.8-0.8-0.2-0.8-0.60.4-0.3-0.5
Mean time between licks in bursts0.40.53.50.8-0.6-0.40.6-0.60.3-0.30.2-1.90.10.9-0.50.0
Mean num. licks in bursts0.10.10.30.3-0.3-0.50.4-0.4-0.20.20.60.10.2-0.4-0.30.5
Std. dev. time between licks in bursts0.40.50.90.9-0.8-0.90.9-0.9-0.50.50.80.00.50.3-0.70.8
Water consumed over 24 hours0.50.60.8-0.90.90.9-0.90.90.6-0.6-0.80.4-0.6-0.10.6-0.9
Indifference point 0 sec0.71.12.31.3-1.1-1.51.4-1.4-0.60.51.30.70.10.2-0.91.2
Indifference point AUC0.20.20.40.6-0.5-0.50.6-0.60.2-0.20.4-0.5-0.10.6-0.50.2
Indifference point function ln k0.20.31.0-0.40.30.5-0.40.50.5-0.5-0.6-1.0-0.20.20.3-0.6
Indifference point function log k0.20.31.0-0.40.30.5-0.40.50.5-0.5-0.6-1.0-0.20.20.3-0.6
Delay discounting total patch changes 0 sec0.40.61.41.1-0.8-1.21.1-1.1-0.20.21.00.4-0.20.2-0.80.8
Delay discounting total patch changes 12 sec1.62.24.21.6-1.6-1.71.6-1.6-1.51.51.9-0.41.4-0.6-0.82.0
Delay discounting total patch changes 18 sec0.10.20.70.1-0.00.20.00.00.7-0.6-0.4-0.6-0.50.80.1-0.5
Delay discounting total patch changes 24 sec0.30.40.80.8-0.9-0.80.8-0.80.2-0.10.8-0.5-0.00.4-0.70.6
Delay discounting total patch changes 6 sec1.21.93.11.6-1.5-1.81.7-1.7-1.11.21.70.60.9-0.1-0.91.8
Delay discounting time to switch 0 sec0.30.50.70.8-0.7-0.80.8-0.80.5-0.50.8-0.8-0.30.7-0.80.4
Delay discounting water rate 0 sec0.50.72.5-0.20.10.2-0.30.3-1.41.40.1-0.01.4-1.60.70.6
Delay discounting water rate 12 sec0.10.20.3-0.60.20.5-0.60.60.10.0-0.3-0.40.2-0.50.2-0.3
Delay discounting water rate 18 sec0.30.31.00.1-0.3-0.20.1-0.1-1.00.90.4-0.51.0-0.80.10.7
Delay discounting water rate 24 sec1.01.34.6-0.30.10.4-0.50.5-1.71.70.2-1.02.0-2.10.80.8
Delay discounting water rate 6 sec0.10.10.30.3-0.3-0.20.2-0.20.1-0.00.1-0.40.10.4-0.50.1
Locomotor activity0.20.30.80.6-0.6-0.70.7-0.70.1-0.10.60.2-0.20.3-0.90.4
Locomotor testing distance1.01.64.61.1-0.9-1.41.3-1.40.9-1.11.01.1-1.41.7-2.10.3
Locomotor testing rearing0.20.33.2-0.20.1-0.2-0.0-0.0-0.0-0.00.21.8-0.5-0.2-0.30.1
Light reinforcement 10.30.53.70.1-0.1-0.60.4-0.5-0.30.20.41.9-0.60.8-0.90.4
Light reinforcement 20.20.30.6-0.80.60.6-0.70.7-0.20.2-0.50.1-0.0-0.50.4-0.3
Reaction time number correct0.60.82.2-0.20.30.2-0.10.11.2-1.2-0.51.1-1.51.5-0.7-0.8
Reaction time mean minus median0.70.83.60.1-0.80.00.1-0.1-1.21.30.3-1.91.7-0.30.60.7
Reaction time mean minus median AUC0.50.62.20.8-1.1-0.70.8-0.8-0.50.50.7-1.50.70.4-0.30.7
Reaction time num false alarms0.10.10.3-0.40.40.3-0.40.40.5-0.5-0.30.3-0.5-0.0-0.1-0.5
Reaction time num false alarms AUC0.10.20.3-0.60.50.5-0.60.50.3-0.3-0.40.0-0.3-0.30.1-0.4
Reaction time trials correct on left0.60.82.2-0.20.30.2-0.10.11.2-1.2-0.51.1-1.51.5-0.7-0.8
Reaction time trials on left0.60.82.4-0.10.30.1-0.0-0.01.2-1.3-0.51.1-1.51.5-0.7-0.8
Reaction time mean0.60.82.1-0.60.00.6-0.60.7-1.01.1-0.2-1.31.4-1.41.10.2
Reaction time mean AUC0.50.72.2-0.2-0.40.2-0.20.2-1.11.20.2-1.31.5-1.10.70.6
Median of all reaction times0.60.92.5-0.80.40.9-0.90.9-0.80.9-0.4-0.91.2-1.61.3-0.0
Reaction time omissions0.40.54.50.4-0.8-0.10.3-0.30.2-0.20.1-2.10.31.0-0.20.1
Reaction time false alarm rate0.10.20.9-0.40.30.3-0.40.4-0.30.3-0.1-0.40.4-0.90.4-0.0
Reaction time premature initiation rate0.70.93.6-0.80.60.5-0.70.7-1.01.1-0.11.50.8-1.91.00.3
Reaction time premature initiations0.30.42.9-0.60.50.3-0.40.4-0.20.3-0.11.7-0.1-0.80.4-0.0
Std. dev. reaction times0.40.63.70.2-0.8-0.10.2-0.1-0.70.80.3-1.91.2-0.30.30.5
Reaction time trials completed0.60.82.4-0.10.30.1-0.0-0.01.2-1.3-0.51.1-1.51.5-0.7-0.8
Reaction time trials AUC0.60.92.5-0.20.30.1-0.00.01.2-1.2-0.51.4-1.51.6-0.7-0.8
Social response proportion0.20.31.90.2-0.40.10.1-0.0-0.50.5-0.0-1.40.80.20.10.2
Social responses0.30.31.10.4-0.5-0.20.3-0.3-0.80.70.4-1.01.0-0.0-0.20.6
Social time2.22.95.3-2.11.92.3-2.22.20.1-0.2-2.2-0.90.0-0.92.3-1.8
Conditioned locomotion0.60.82.5-0.10.40.0-0.0-0.01.4-1.4-0.40.8-1.61.1-0.6-0.8
Cocaine response after cond. corrected0.30.32.60.4-0.5-0.20.3-0.3-0.20.20.4-1.60.5-0.4-0.00.4
Cocaine response after cond. not corrected0.40.42.90.3-0.5-0.20.2-0.2-0.40.40.6-1.70.8-0.80.10.6
Cocaine response before conditioning0.10.10.4-0.20.00.0-0.10.1-0.60.60.20.40.5-0.60.20.3
Saline control response0.30.40.60.7-0.7-0.60.6-0.6-0.60.60.6-0.80.7-0.1-0.40.7
Condit. Reinf. active minus inactive responses1.41.73.91.4-1.3-1.61.6-1.60.8-0.81.20.1-1.02.0-1.90.6
Condit. Reinf. active-inactive response ratio1.21.33.21.1-0.9-1.11.2-1.21.2-1.20.8-0.2-1.21.8-1.60.2
Condit. Reinf. active responses1.41.93.51.7-1.6-1.91.9-1.9-0.00.01.50.0-0.21.5-1.81.2
Condit. Reinf. inactive responses0.70.81.60.9-0.9-0.90.9-0.9-1.21.20.9-0.11.2-0.2-0.41.1
Condit. Reinf. lever presses0.00.10.60.2-0.2-0.20.2-0.20.1-0.10.1-0.8-0.00.1-0.20.1
Condit. Reinf. lever reinforcers received1.11.62.91.5-1.4-1.61.7-1.70.1-0.11.3-0.1-0.21.4-1.71.0
Pavlov. Cond. lever latency0.60.81.6-1.11.21.0-1.01.00.3-0.3-1.11.3-0.5-0.30.9-0.9
Pavlov. Cond. magazine entry latency1.61.93.4-1.71.51.8-1.81.80.5-0.5-1.7-0.4-0.2-0.61.6-1.5
Pavlov. Cond. change in total contacts0.50.72.2-0.4-0.10.2-0.30.3-1.41.40.2-0.21.5-1.30.70.7
Pavlov. Cond. index score0.20.30.7-0.60.20.5-0.60.6-0.50.5-0.3-0.60.7-0.80.7-0.1
Pavlov. Cond. latency score0.30.30.6-0.70.40.7-0.70.7-0.30.3-0.5-0.30.5-0.70.8-0.3
Pavlov. Cond. lever contacts0.60.81.90.8-1.1-0.80.8-0.8-0.80.81.0-1.41.1-0.4-0.41.0
Pavlov. Cond. magazine entry number1.51.93.71.8-1.4-1.71.8-1.80.5-0.51.4-0.2-0.71.5-1.90.9
Pavlov. Cond. intertrial magazine entries0.30.41.70.00.0-0.30.2-0.30.7-0.70.11.3-1.01.0-0.7-0.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.70.30.6-0.70.7-0.60.6-0.4-0.60.8-0.90.8-0.1
Pavlov. Cond. response bias0.30.51.40.2-0.6-0.20.2-0.2-0.90.90.5-1.11.2-0.70.10.7
Conditioned reinforcement - actives0.40.42.30.4-0.4-0.10.2-0.2-0.50.60.1-1.50.8-0.70.40.3
Conditioned reinforcement - inactives0.30.31.4-0.40.80.4-0.50.50.1-0.0-0.61.2-0.3-0.60.8-0.5
Conditioned locomotion1.51.83.11.4-1.5-1.41.4-1.4-1.31.51.60.41.4-0.6-0.91.8
Intermittent access intake day 1-15 change0.30.30.5-0.40.70.5-0.40.40.5-0.6-0.6-0.5-0.6-0.20.7-0.7
Intermittent access intake escalation0.40.40.7-0.40.70.6-0.50.50.5-0.6-0.7-0.8-0.6-0.30.8-0.7
Intermittent access intake escalation 20.40.41.3-0.40.40.6-0.50.6-0.10.1-0.4-1.20.3-0.90.9-0.2
Intermitt. access day 1 inactive lever presses0.10.10.3-0.40.30.5-0.40.40.1-0.0-0.50.10.1-0.00.5-0.4
Intermitt. access day 15 inactive lever presses1.31.47.8-1.21.41.1-1.11.10.1-0.0-1.22.8-0.4-0.41.0-0.9
Intermitt. access escalation Index3.32.932.8-0.91.20.2-0.40.30.0-0.0-0.85.7-1.30.40.1-0.7
Intermittent access day 1 total infusions0.70.82.0-0.90.70.7-0.90.9-0.80.9-0.51.40.6-1.31.0-0.1
Intermittent access day 15 total infusions1.31.43.0-1.41.41.2-1.31.3-0.50.5-1.11.70.0-1.51.6-0.6
Intermittent access terminal intake (last 3 days)0.60.61.8-0.81.00.9-0.90.9-0.20.2-0.80.20.0-1.11.3-0.5
Intermittent access total infusions0.30.41.0-0.60.80.7-0.70.7-0.30.3-0.60.20.1-0.71.0-0.4
Intermittent access day 1 locomotion0.60.61.60.4-0.5-0.30.3-0.3-1.11.30.6-0.01.3-1.10.11.0
Intermittent access day 15 total locomotion0.91.03.6-0.50.10.6-0.70.7-1.11.3-0.0-0.91.6-1.91.00.5
Intermittent access total locomotion1.11.24.00.1-0.6-0.10.0-0.0-1.61.80.7-0.12.0-1.90.31.2
Intermittent access standard deviation0.20.30.50.4-0.4-0.50.4-0.5-0.60.70.50.60.4-0.4-0.20.7
Cocaine induced anxiety0.20.21.40.1-0.1-0.30.2-0.2-0.40.40.31.20.0-0.2-0.60.3
Post-drug Anxiety0.70.81.91.1-1.1-1.11.0-1.0-0.30.41.1-0.70.40.1-1.40.9
Baseline Anxiety0.70.75.00.5-1.0-0.40.4-0.4-0.30.40.8-2.21.0-0.4-0.50.7
Lifetime Intake0.20.31.2-0.50.50.4-0.50.4-0.30.4-0.41.10.1-0.50.7-0.2
Incentive Sensitization - Responses0.60.62.70.10.50.3-0.10.11.1-1.2-0.6-1.6-1.00.30.7-0.8
Incentive Sensitization - Breakpoint0.50.53.10.30.30.20.00.01.0-1.0-0.4-1.8-0.80.30.6-0.7
Progressive ratio test 1 active lever presses0.20.22.2-0.20.30.0-0.10.0-0.10.1-0.21.5-0.30.10.4-0.2
Progressive ratio test 1 breakpoint0.30.33.0-0.10.2-0.10.1-0.1-0.00.0-0.11.7-0.50.20.2-0.1
Progressive ratio test 1 inactive lever presses0.60.65.2-0.70.40.3-0.50.5-0.60.8-0.32.30.4-0.80.40.0
Progressive ratio test 2 active lever presses0.10.11.30.3-0.1-0.10.2-0.10.1-0.1-0.0-1.20.0-0.20.4-0.0
Progressive ratio test 2 breakpoint0.10.10.40.5-0.2-0.30.4-0.40.2-0.20.1-0.6-0.20.20.2-0.0
Progressive ratio test 2 inactive lever presses0.10.20.5-0.10.10.1-0.10.1-0.60.7-0.10.70.4-0.70.40.2
Total sessions with >9 infusions0.50.64.9-0.30.60.1-0.10.10.4-0.4-0.52.2-0.90.60.4-0.6
Short access day 1 total inactive lever presses1.11.214.0-0.00.2-0.40.3-0.3-0.00.1-0.03.7-0.70.5-0.4-0.0
Short access day 10 total inactive lever presses1.11.25.4-1.31.31.0-1.21.1-0.40.4-0.82.3-0.0-0.91.0-0.4
Short access day 1 total infusions0.50.53.60.3-0.2-0.50.5-0.50.2-0.20.11.9-0.61.1-0.5-0.0
Short access day 10 total infusions1.11.28.9-1.01.10.6-0.80.8-0.40.4-0.73.0-0.3-0.81.0-0.4
Short access total infusions0.40.44.40.10.1-0.30.3-0.3-0.00.0-0.02.1-0.50.5-0.1-0.0
Short access day 1 locomotion0.30.31.50.4-0.1-0.30.5-0.50.3-0.4-0.01.2-0.51.2-0.3-0.1
Short access day 10 total locomotion2.22.44.31.6-1.8-1.51.5-1.4-1.41.61.9-1.01.9-0.8-1.12.1
Short access total locomotion1.41.42.21.5-1.5-1.41.4-1.4-0.91.01.4-0.41.10.2-1.11.5
Compulsive drug intake2.01.911.9-1.11.60.7-0.80.80.9-1.0-1.13.4-1.70.20.7-1.2
One hour access (0.3 mA shock)2.02.34.0-1.91.71.5-1.71.7-0.50.6-1.32.00.1-2.01.9-0.9
One hour access (shock baseline)0.50.61.9-0.3-0.10.4-0.40.4-1.01.10.0-0.91.2-1.40.70.4
Number of responses in last shaping day0.90.95.1-1.00.20.7-0.80.8-1.01.2-0.62.30.9-0.50.3-0.1
Context. condit. distance diff. score1.21.53.0-1.41.61.5-1.51.5-0.00.0-1.50.4-0.0-0.91.7-1.2
Locomotion velocity, session 13.53.87.61.4-1.8-1.71.5-1.5-2.72.72.3-0.42.6-1.6-0.62.8
Locomotion distance, session 10.30.42.80.6-0.7-0.40.4-0.4-0.30.30.6-1.70.7-0.3-0.20.6
Locomotion velocity, session 23.94.68.62.3-2.6-2.52.4-2.4-1.71.72.9-1.01.7-0.3-1.82.9
Locomotion distance, session 20.91.32.51.1-1.2-1.21.1-1.1-1.11.11.5-0.71.2-0.7-0.71.6
Locomotion velocity, session 30.91.12.41.5-1.1-1.41.5-1.40.2-0.21.1-0.6-0.20.6-1.20.8
Locomotion distance, session 30.91.02.30.5-0.6-0.70.6-0.6-1.51.51.00.91.2-1.0-0.11.3
Stereotopy head waving bouts, day 31.01.22.51.3-1.2-1.61.5-1.5-0.10.11.40.7-0.20.5-1.41.2
Stereotopy head waving duration, day 32.02.44.72.0-1.7-2.22.1-2.10.2-0.21.90.1-0.51.2-2.11.3
Locomotion velocity, session 70.50.61.50.5-0.5-0.50.5-0.5-1.21.20.5-0.01.1-0.80.40.9
Locomotion distance, session 70.91.12.60.9-0.9-0.70.7-0.7-1.41.40.9-1.31.6-1.00.41.2
Stereotopy head waving bouts, day 71.51.73.11.7-1.5-1.71.7-1.70.4-0.41.4-0.6-0.51.3-1.80.9
Stereotopy head waving duration, day 71.01.32.81.2-1.0-1.21.3-1.31.0-1.00.8-0.6-1.01.5-1.70.2
Locomotion velocity, session 81.31.53.21.1-1.1-1.31.1-1.2-1.41.41.60.21.3-0.9-0.61.8
Locomotion distance, session 80.50.72.4-0.50.50.7-0.70.7-0.90.9-0.4-0.81.0-1.61.3-0.0
Degree of sensitization distance0.20.20.7-0.30.30.4-0.40.4-0.20.2-0.4-0.80.4-0.50.8-0.2
Degree of sensitization stereotypy0.80.92.21.0-0.7-0.80.9-0.91.0-1.00.4-0.8-0.91.5-1.2-0.1
Condit. Reinf. active minus inactive responses1.71.93.2-1.11.31.1-1.00.91.5-1.5-1.61.6-1.81.60.4-1.8
Condit. Reinf. active-inactive response ratio2.93.26.8-1.21.51.2-1.01.02.3-2.3-1.91.8-2.62.10.2-2.3
Condit. Reinf. active responses0.40.51.1-0.70.70.7-0.60.60.6-0.6-0.81.1-0.80.80.3-0.8
Condit. Reinf. inactive responses1.01.12.60.7-1.0-0.70.6-0.6-1.41.41.2-1.11.6-1.0-0.11.4
Incentive salience index mean1.21.54.7-0.40.60.5-0.30.31.6-1.6-1.01.3-1.92.2-0.4-1.3
Condit. Reinf. lever presses1.21.67.20.4-0.2-0.30.5-0.51.8-1.8-0.20.1-1.92.7-1.3-0.8
Time in familiar zone, hab. session 10.70.72.0-0.90.90.6-0.80.8-0.70.7-0.51.40.3-1.11.2-0.1
Time in novel zone, hab. session 10.20.20.5-0.20.20.4-0.30.30.7-0.7-0.5-0.7-0.40.40.0-0.6
Total zone transitions, hab. session 10.60.82.70.3-0.3-0.40.2-0.2-1.41.40.8-0.31.3-1.70.51.1
Total locomotion distance, hab. session 10.40.62.10.1-0.1-0.30.1-0.1-1.21.20.60.41.0-1.40.60.9
Locomotion velocity, hab. session 10.60.91.90.8-0.8-0.90.8-0.8-1.21.21.2-0.21.1-1.0-0.21.4
Time in familiar zone, hab. session 22.02.03.6-1.71.81.9-1.81.80.4-0.4-1.90.4-0.4-0.61.7-1.6
Time in novel zone, hab. session 20.40.40.90.8-0.8-0.90.8-0.8-0.30.30.9-0.20.30.0-0.70.8
Total zone transitions, hab. session 20.30.30.60.7-0.7-0.70.7-0.7-0.20.20.8-0.40.3-0.2-0.50.7
Total locomotion distance, hab. session 20.20.30.50.7-0.6-0.70.7-0.7-0.10.10.6-0.30.10.0-0.40.6
Locomotion velocity, hab. session 20.20.30.60.7-0.7-0.80.7-0.7-0.30.30.8-0.20.3-0.1-0.40.7
Novel to familiar place preference ratio1.31.42.21.5-1.4-1.31.4-1.40.5-0.51.1-1.1-0.41.4-1.50.7
Novelty place preference1.41.52.41.5-1.4-1.41.5-1.50.5-0.51.2-1.1-0.31.5-1.60.8
Time in novel zone, NPP test0.80.81.81.1-0.9-0.91.1-1.10.6-0.60.7-0.8-0.51.3-1.10.4
Total zone transitions, NPP test0.81.12.90.2-0.5-0.40.2-0.2-1.71.70.9-0.01.7-1.50.31.3
Total locomotion distance, NPP test0.91.22.80.7-0.8-0.80.7-0.7-1.71.71.1-0.31.6-1.20.01.5
Locomotion velocity, NPP test1.52.14.21.1-1.3-1.31.1-1.1-2.02.01.7-0.41.9-1.3-0.32.0
Pavlov. Cond. lever latency3.54.513.1-1.91.61.9-2.12.1-2.22.2-1.20.52.3-3.63.1-0.1
Pavlov. Cond. magazine entry latency0.70.93.0-0.10.30.10.0-0.01.4-1.4-0.50.8-1.61.7-0.7-0.9
Pavlov. Cond. change in total contacts2.22.35.51.5-1.5-1.71.7-1.71.2-1.21.30.1-1.32.3-2.30.5
Pavlov. Cond. index score1.41.75.81.0-0.8-1.11.2-1.21.4-1.40.60.4-1.62.4-1.9-0.1
Pavlov. Cond. latency score1.92.57.51.4-1.1-1.51.6-1.61.6-1.60.80.3-1.82.7-2.30.1
Pavlov. Cond. lever contacts2.42.99.61.3-1.0-1.41.5-1.52.0-2.00.70.1-2.23.1-2.4-0.2
Pavlov. Cond. magazine entry number0.70.92.40.4-0.5-0.30.2-0.2-1.21.20.7-1.51.5-1.50.41.0
Pavlov. Cond. intertrial magazine entries0.30.40.80.1-0.3-0.30.2-0.2-0.90.90.70.20.9-0.90.10.9
Pavlov. Cond. lever-magazine prob. diff.1.72.16.91.2-1.0-1.21.3-1.41.6-1.60.70.1-1.82.6-2.1-0.1
Pavlov. Cond. response bias1.31.65.80.2-0.1-0.30.4-0.41.8-1.8-0.30.7-2.02.4-1.3-0.9
Bone: apparent density0.10.21.20.5-0.4-0.20.4-0.30.4-0.40.0-1.1-0.10.6-0.2-0.1
Bone surface0.81.52.71.6-1.4-1.61.6-1.60.3-0.31.2-0.3-0.31.2-1.60.9
Bone volume0.30.61.31.0-0.7-0.70.8-0.80.6-0.60.4-1.1-0.41.0-0.70.1
Bone: connectivity density0.30.51.01.0-0.9-0.90.9-0.90.2-0.20.7-0.6-0.10.7-0.90.4
Bone: cortical apparent density0.40.52.8-0.90.70.6-0.70.7-0.20.2-0.61.7-0.1-0.20.6-0.3
Bone: cortical area0.10.20.40.5-0.4-0.60.6-0.6-0.00.00.50.4-0.10.0-0.20.4
Bone: cortical porosity0.50.51.11.0-0.8-1.01.0-1.00.0-0.01.0-0.4-0.10.2-0.80.8
Bone: cortical porosity0.40.50.70.8-0.6-0.80.8-0.80.6-0.60.6-0.1-0.80.7-0.80.2
Bone: cortical thickness0.20.41.1-0.30.50.1-0.20.20.9-0.9-0.31.0-1.10.30.1-0.6
Bone: cortical thickness1.21.42.2-1.21.51.2-1.31.31.2-1.2-1.21.1-1.2-0.51.0-1.4
Bone: cortical tissue density0.40.62.5-1.00.80.7-0.80.8-0.40.4-0.61.60.1-0.30.7-0.3
Bone: elastic displacement0.40.42.50.4-0.3-0.20.3-0.20.9-0.90.1-1.6-0.50.4-0.3-0.3
Bone: elastic work0.20.21.90.4-0.3-0.30.3-0.30.2-0.20.3-1.40.1-0.4-0.10.2
Bone: endosteal estimation1.22.53.71.8-1.7-1.51.6-1.6-1.71.71.6-1.71.9-0.4-0.71.9
Bone: endosteal perimeter0.91.83.31.8-1.6-1.71.7-1.7-0.70.71.5-0.90.70.4-1.21.5
Bone: final force0.50.91.61.1-0.9-1.21.1-1.1-0.80.81.30.20.6-0.3-0.71.3
Bone: final moment0.50.81.41.1-0.9-1.11.1-1.1-0.70.71.2-0.20.6-0.3-0.61.2
Bone: marrow area1.32.94.31.9-1.8-1.71.7-1.7-1.81.81.8-1.71.9-0.4-0.82.1
Bone: maximum diameter0.30.61.61.0-0.8-0.91.0-1.00.2-0.20.5-0.0-0.41.3-0.80.3
Bone: maximum force1.12.03.61.8-1.6-1.91.8-1.8-0.80.81.9-0.10.70.0-1.31.8
Bone: maximum moment0.91.62.91.7-1.5-1.71.7-1.6-0.70.71.7-0.40.60.1-1.11.6
Bone: minimum diameter0.91.73.21.8-1.6-1.61.7-1.70.0-0.01.4-1.20.10.9-1.31.1
Bone: periosteal estimation0.91.82.91.7-1.5-1.61.6-1.6-1.21.21.5-0.91.2-0.0-0.81.6
Bone: periosteal perimeter0.50.81.71.3-1.0-1.21.3-1.3-0.20.21.0-0.20.10.5-0.80.9
Bone: post-yield work0.10.10.4-0.10.10.1-0.10.10.5-0.5-0.30.1-0.50.6-0.0-0.4
Bone: stiffness1.01.63.11.2-1.2-1.41.3-1.3-1.41.41.60.61.2-0.4-0.71.8
Bone: tissue strength0.90.92.00.9-1.0-0.80.8-0.8-1.01.01.0-1.41.2-0.3-0.31.1
Bone: trabecular number0.00.00.00.1-0.1-0.10.1-0.1-0.10.10.0-0.20.2-0.20.20.1
Bone: trabecular spacing0.20.20.4-0.60.50.6-0.60.60.1-0.1-0.5-0.2-0.1-0.40.5-0.4
Bone: trabecular thickness0.10.10.70.4-0.3-0.10.2-0.2-0.00.00.0-0.90.20.20.10.1
Bone: trabecular tissue density0.10.21.4-0.0-0.0-0.20.2-0.20.1-0.10.11.2-0.40.5-0.30.1
Breakpoint value in progressive ratio session0.40.51.70.10.00.2-0.00.00.9-1.0-0.4-1.3-0.71.30.1-0.6
Distance traveled before self-admin0.40.42.10.5-0.4-0.60.6-0.6-0.00.00.31.4-0.31.0-0.80.2
Distance traveled after self-admin1.31.52.61.6-1.4-1.31.5-1.50.1-0.11.2-1.50.11.2-1.50.8
Delta time in closed arm before/after self-admin0.90.92.91.1-1.1-0.91.0-1.0-0.20.10.9-1.70.40.6-1.00.8
Delta time in open arm before/after self-admin0.30.31.8-0.40.50.3-0.40.40.2-0.1-0.41.3-0.4-0.20.3-0.4
Diff in mean of infusions in LGA sessions1.01.11.9-1.41.31.3-1.31.30.1-0.1-1.21.2-0.2-0.61.3-1.0
Extinction: sum of active levers before priming0.60.61.01.0-0.8-1.01.0-1.00.1-0.20.9-0.3-0.20.8-1.00.7
Active lever presses in extinction session 60.80.85.91.0-0.8-0.50.7-0.70.3-0.30.5-2.40.30.8-0.70.3
Delta distance traveled before/after self-admin0.30.43.00.6-0.6-0.40.4-0.40.1-0.10.5-1.70.2-0.1-0.30.4
Delta ambulatory time before/after self-admin1.21.32.21.5-1.3-1.51.5-1.50.2-0.21.4-1.1-0.10.6-1.31.1
Time in closed arm before self-admin0.10.10.3-0.30.40.5-0.40.40.3-0.3-0.5-0.6-0.10.10.4-0.5
Time in closed arm after self-admin0.50.51.90.7-0.6-0.50.6-0.60.6-0.60.3-1.4-0.31.0-0.80.0
Time in open arm before self-admin0.50.61.40.7-0.7-1.00.9-0.9-0.10.10.81.2-0.10.4-0.90.7
Time in open arm after self-admin0.20.21.80.3-0.2-0.50.4-0.4-0.20.20.41.4-0.10.3-0.50.3
Sum of active levers in priming session hrs 5-61.11.16.71.3-1.0-0.81.0-1.00.3-0.40.8-2.60.20.7-0.80.5
Time to tail flick, vehicle, before self-admin1.71.83.0-1.61.61.7-1.71.7-0.30.3-1.50.90.3-1.21.7-1.2
Time to tail flick, vehicle, after self-admin0.91.02.3-1.21.11.3-1.21.2-0.30.3-1.20.40.3-0.61.5-0.7
Time to tail flick, test, before self-admin2.82.84.5-2.12.02.0-2.02.00.0-0.0-2.01.9-0.3-0.82.1-1.6
Time to tail flick, test, after self-admin3.94.07.6-2.52.52.2-2.42.40.2-0.2-2.22.8-0.6-1.12.5-1.9
Delta time to tail flick, vehicle, before/after SA0.30.30.50.5-0.6-0.70.6-0.7-0.00.00.6-0.2-0.10.6-0.70.6
Delta time to tail flick, test, before/after SA0.80.71.2-1.01.00.9-1.01.00.1-0.2-0.91.1-0.3-0.51.0-0.8
Ambulatory time before self-admin0.40.41.1-0.80.60.8-0.80.8-0.20.3-0.81.10.3-0.20.6-0.6
Ambulatory time after self-admin0.50.51.10.8-0.6-0.90.9-0.90.3-0.30.70.7-0.40.8-1.00.4
Total heroin consumption0.50.61.1-0.50.70.9-0.70.70.6-0.7-1.1-1.1-0.40.60.8-1.1
Area under the delay curve1.01.12.71.6-1.0-1.41.6-1.5-0.00.01.0-0.5-0.20.9-1.10.8
Delay disc. indifference point, 0s delay1.71.85.40.00.70.00.1-0.12.0-1.9-0.72.1-2.31.9-0.6-1.3
Delay disc. indifference point, 16s delay0.30.31.11.0-0.3-0.80.9-0.9-0.1-0.20.6-0.2-0.40.2-0.60.3
Delay disc. indifference point, 2s delay0.80.91.61.1-0.6-1.21.3-1.3-0.30.20.81.0-0.31.1-1.20.7
Delay disc. indifference point, 24s delay0.50.51.30.7-0.5-1.00.8-0.9-0.20.00.81.2-0.5-0.1-0.70.5
Delay disc. indifference point, 4s delay2.52.67.32.2-1.9-1.71.9-1.90.4-0.11.4-2.70.31.5-1.61.1
Delay disc. indifference point, 8s delay0.20.20.40.7-0.4-0.40.6-0.6-0.50.40.2-0.10.30.3-0.10.4
Delay discount exponential model param1.11.22.7-1.61.11.4-1.61.50.2-0.2-1.10.8-0.0-0.71.1-0.9
Delay discount hyperbolic model param1.11.22.7-1.71.11.4-1.61.50.2-0.2-1.10.9-0.0-0.91.1-0.9
Fecal boli incidents, locomotor time 10.70.82.01.1-0.5-0.81.0-1.00.7-0.90.6-0.7-0.61.4-1.40.1
Change in fecal boli incidents, locomotor task1.51.43.7-1.10.51.2-1.21.3-0.91.0-0.8-1.31.2-1.91.8-0.3
Time >=10cm from walls, locomotor time 10.50.51.1-0.90.71.0-0.90.9-0.40.2-0.90.30.3-0.51.1-0.6
Bouts of movement, locomotor time 10.50.51.3-1.00.30.9-1.01.0-0.10.3-0.6-0.30.4-1.21.0-0.4
Total resting periods, locomotor time 10.50.61.2-1.00.51.0-1.01.00.4-0.1-0.7-0.10.1-1.10.9-0.6
Rest time, locomotor task time 11.82.03.4-1.81.81.7-1.81.80.1-0.0-1.61.3-0.3-1.31.8-1.2
Distance moved, locomotor task time 10.91.07.90.7-1.1-0.40.6-0.5-0.10.20.5-2.80.90.6-0.50.5
Vertical activity count, locomotor time 10.20.21.10.4-0.6-0.30.3-0.3-0.30.30.3-1.00.50.4-0.40.4
Time >=10cm from walls, locomotor time 20.10.10.6-0.20.40.1-0.20.1-0.50.50.00.80.4-0.50.30.2
Bouts of movement, locomotor time 20.30.40.80.4-0.5-0.70.5-0.5-0.70.50.90.10.3-0.7-0.50.9
Total resting periods, locomotor time 20.30.30.90.1-0.3-0.40.2-0.3-0.90.70.60.60.4-1.0-0.10.7
Rest time, locomotor task time 21.31.52.6-1.51.31.5-1.61.60.2-0.2-1.3-0.1-0.2-1.61.6-1.1
Distance moved, locomotor task time 20.30.42.60.4-0.6-0.20.4-0.30.00.00.3-1.60.50.8-0.50.2
Vertical activity count, locomotor time 20.70.76.4-0.50.70.1-0.20.2-0.91.0-0.12.50.3-0.40.40.3
Weight adjusted by age0.80.92.61.2-0.6-0.91.1-1.1-0.6-0.80.6-1.6-0.51.4-0.90.3
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.10.00.2-0.10.10.30.1-0.3-0.20.30.70.3-0.1
Locomotion in novel chamber0.20.20.80.0-0.6-0.0-0.00.00.00.50.3-0.90.7-0.6-0.10.5
Locomotion in novel chamber post-restriction1.11.35.60.2-0.1-0.00.1-0.12.4-1.9-0.4-0.9-1.71.4-0.8-1.0
Progressive ratio0.20.20.4-0.50.50.5-0.50.50.4-0.2-0.5-0.2-0.3-0.10.6-0.5
Food seeking constrained by brief footshock0.70.93.6-0.10.5-0.0-0.00.01.9-1.5-0.11.2-1.70.3-0.7-0.7
Seeking ratio, punishment vs. effort0.50.61.90.7-0.6-0.70.7-0.71.1-1.00.6-0.1-0.90.8-1.4-0.0
Run reversals in cocaine runway, females2.32.37.3-0.91.40.5-0.70.72.0-2.2-0.82.5-2.70.4-0.0-1.6
Run reversals in cocaine runway, males5.95.719.7-1.92.71.7-1.71.62.1-2.1-2.44.4-3.21.11.4-2.6
Latency to leave start box in cocaine runway1.71.819.20.5-0.6-0.00.2-0.21.0-1.30.2-4.4-0.20.6-0.5-0.4
Latency to leave start box in cocaine runway, F2.02.27.40.10.40.2-0.00.02.5-2.7-0.5-2.2-2.31.1-0.4-1.5
Latency to leave start box in cocaine runway, M1.31.39.70.6-0.9-0.20.3-0.3-0.80.80.6-3.11.5-0.70.10.8
Cd content in liver1.11.22.1-1.31.41.2-1.21.20.6-0.6-1.31.4-0.9-0.10.9-1.2
Co content in liver0.10.10.50.2-0.3-0.20.2-0.20.4-0.40.1-0.7-0.20.4-0.4-0.1
Cu content in liver0.20.31.8-0.40.60.4-0.40.40.1-0.2-0.51.3-0.40.30.2-0.5
Fe content in liver0.30.30.80.7-0.6-0.50.6-0.60.6-0.40.3-0.9-0.30.8-0.60.1
K content in liver0.20.20.40.6-0.5-0.70.7-0.7-0.30.30.50.40.20.1-0.50.5
Mg content in liver0.50.52.3-0.60.70.5-0.60.6-0.50.6-0.41.50.3-1.00.8-0.1
Mn content in liver0.20.30.50.5-0.5-0.60.5-0.5-0.30.30.70.00.4-0.6-0.40.7
Na content in liver0.70.71.31.2-1.0-1.11.1-1.1-0.40.40.9-0.40.30.4-0.80.9
Rb content in liver2.22.711.6-1.81.61.2-1.51.5-1.41.3-0.83.40.6-2.11.7-0.2
Se content in liver0.30.30.8-0.50.70.6-0.60.60.5-0.3-0.90.6-0.4-0.10.7-0.8
Sr content in liver0.90.81.5-1.21.01.2-1.21.20.0-0.0-1.10.10.0-0.61.2-0.9
Zn content in liver0.80.91.91.1-0.9-1.01.1-1.10.8-0.80.7-0.6-0.71.4-1.40.2