Hub : Genes

Trpc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000054902 0.06 0.03 2.1e-05 0.03 0.03 0.03 0.03 3.0e-04 1.4e-04 4.6e-04 6.8e-04
2 Adipose intron excision ratio chr8:96280099:96282351 0.04 0.02 1.4e-04 0.02 0.02 0.01 0.02 3.1e-03 1.1e-03 7.2e-03 4.6e-03
3 BLA intron excision ratio chr8:96280099:96282351 0.06 0.04 2.1e-03 0.03 0.05 0.03 0.04 1.0e-02 1.2e-03 9.7e-03 2.7e-03
4 Brain gene expression ENSRNOG00000054902 0.03 0.02 2.5e-03 0.01 0.02 0.01 0.02 2.7e-02 4.4e-03 6.5e-02 8.4e-03
5 Brain intron excision ratio chr8:96280099:96280911 0.13 0.08 3.8e-06 0.07 0.06 0.04 0.07 2.1e-07 1.2e-06 4.8e-05 3.8e-07
6 Brain intron excision ratio chr8:96280099:96282351 0.15 0.06 6.8e-13 0.14 0.13 0.15 0.14 6.2e-13 4.1e-12 1.2e-13 3.0e-13
7 Brain intron excision ratio chr8:96280967:96282351 0.11 0.06 1.1e-07 0.06 0.05 0.06 0.04 7.2e-06 1.8e-05 7.2e-06 9.0e-05
8 Brain mRNA stability ENSRNOG00000054902 0.13 0.07 2.4e-10 0.09 0.1 0.1 0.1 2.6e-08 1.5e-09 1.1e-09 7.3e-10
9 LHb gene expression ENSRNOG00000054902 0.17 0.1 6.0e-03 0 0.09 -0 0.04 2.8e-01 4.7e-03 3.4e-01 3.8e-02
10 Liver gene expression ENSRNOG00000054902 0.1 0.05 7.1e-10 0.08 0.08 0.08 0.08 2.5e-09 4.6e-09 2.2e-09 2.7e-09
11 NAcc gene expression ENSRNOG00000054902 0.05 0.04 1.6e-03 0 0.04 0.04 0.01 1.3e-01 8.8e-04 1.0e-03 3.6e-02
12 NAcc intron excision ratio chr8:96280099:96282351 0.09 0.05 2.8e-05 0.07 0.06 0.06 0.06 6.2e-06 4.5e-05 2.0e-05 1.9e-05
13 PL isoform ratio ENSRNOT00000079965 0.04 0.03 3.6e-03 0.03 0.03 0.03 0.03 4.6e-03 4.4e-03 2.2e-03 3.5e-03
14 PL isoform ratio ENSRNOT00000089833 0.04 0.03 4.9e-03 0.02 0.03 0.03 0.03 6.7e-03 4.7e-03 3.1e-03 3.0e-03
15 PL mRNA stability ENSRNOG00000054902 0.06 0.03 4.8e-05 0.09 0.05 0.05 0.06 1.9e-07 1.3e-04 7.3e-05 2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail6.320.535.15.05.85.7-2.6-5.85.9-5.35.31.15.3-0.75.31.1-1.94.7
BMI without tail4.59.321.13.84.63.5-0.3-3.33.9-3.32.92.43.51.43.3-1.31.23.6
Body weight4.920.834.65.65.35.5-2.3-5.55.9-5.35.31.65.3-0.45.32.3-2.94.9
Epididymis fat weight1.02.24.51.82.11.8-0.6-1.71.9-1.61.80.71.80.01.60.30.11.9
Glucose0.30.51.5-0.10.90.7-0.8-0.80.6-0.60.9-0.70.6-0.70.6-0.30.31.2
Heart weight1.52.29.21.70.41.2-0.7-1.41.4-1.21.20.31.3-0.51.23.0-2.71.1
Left kidney weight3.811.017.53.34.24.2-2.5-3.94.0-3.93.9-0.04.0-1.53.90.3-1.43.9
Right kidney weight3.810.718.33.44.14.3-2.5-3.73.9-3.83.7-0.13.8-1.53.81.0-1.93.8
Tail length0.51.67.22.01.00.41.70.20.7-0.2-0.12.70.52.30.2-0.31.31.0
Length with tail0.31.03.91.70.40.80.2-0.61.0-0.70.81.10.80.50.72.0-1.50.9
Length without tail1.73.717.91.1-0.11.3-1.7-1.81.4-1.41.7-0.91.1-1.51.43.8-4.20.9
Liver weight, left0.20.32.10.30.90.6-0.3-0.30.5-0.40.3-0.10.4-0.20.4-0.00.31.4
Liver weight, right1.93.26.60.82.62.0-1.7-1.91.9-2.22.0-0.72.1-1.12.2-0.4-0.32.6
Parametrial fat weight0.20.30.7-0.8-0.5-0.70.30.7-0.70.6-0.8-0.2-0.70.2-0.6-0.50.5-0.3
Retroperitoneal fat weight1.03.46.52.62.52.1-0.3-1.92.4-2.01.91.42.10.52.0-0.50.22.3
Intraocular pressure0.71.01.70.91.21.2-0.7-1.31.2-1.21.20.11.3-0.21.2-0.7-0.20.9
Extensor digitorum longus weight2.610.316.82.03.73.8-3.2-3.73.5-3.83.8-1.43.8-2.33.80.4-1.94.1
Soleus weight1.13.36.31.52.52.2-1.4-2.22.2-2.22.2-0.02.2-0.62.2-1.1-0.02.1
Tibialis anterior weight1.44.77.92.62.52.7-1.1-2.42.7-2.52.20.72.7-0.22.51.2-1.42.8
Tibia length0.51.43.71.91.31.30.0-1.21.6-1.20.91.11.20.51.21.4-0.81.3
Number of licking bursts0.10.20.4-0.4-0.6-0.50.20.6-0.50.5-0.6-0.2-0.3-0.0-0.50.4-0.0-0.2
Food consumed during 24 hour testing period0.50.71.2-0.7-1.1-1.10.80.7-0.70.9-1.00.3-0.80.7-0.91.1-0.3-0.4
Times rat made contact with spout0.80.93.5-0.5-0.30.3-1.4-0.60.2-0.40.5-1.60.5-1.60.41.1-1.90.7
Mean time between licks in bursts0.40.62.9-0.3-0.30.3-1.2-0.40.0-0.30.4-1.20.3-1.40.31.0-1.7-0.1
Mean num. licks in bursts0.81.02.30.30.61.0-1.3-1.20.9-1.01.1-0.90.9-1.21.00.6-1.50.8
Std. dev. time between licks in bursts0.20.31.6-0.9-0.2-0.4-0.20.2-0.40.3-0.1-0.6-0.2-0.4-0.3-1.30.6-0.3
Water consumed over 24 hours0.20.20.7-0.6-0.8-0.80.20.2-0.30.4-0.6-0.1-0.40.1-0.40.6-0.60.2
Indifference point 0 sec0.10.10.50.70.60.60.0-0.10.3-0.2-0.10.30.20.20.20.7-0.20.1
Indifference point AUC0.30.33.50.30.60.40.00.00.00.2-0.10.1-0.2-0.1-0.2-1.90.90.1
Indifference point function ln k0.20.32.00.3-0.5-0.30.4-0.10.2-0.2-0.00.60.20.60.21.4-0.7-0.1
Indifference point function log k0.20.32.00.3-0.5-0.30.4-0.10.2-0.2-0.00.60.20.60.21.4-0.7-0.1
Delay discounting total patch changes 0 sec0.20.30.80.70.70.8-0.3-0.50.6-0.40.30.10.4-0.10.40.9-0.50.4
Delay discounting total patch changes 12 sec0.40.51.70.40.90.9-0.9-0.80.6-0.50.7-0.50.4-0.90.5-1.30.10.5
Delay discounting total patch changes 18 sec0.10.10.80.90.50.70.1-0.30.30.1-0.10.50.10.3-0.10.3-0.20.1
Delay discounting total patch changes 24 sec0.10.10.70.1-0.2-0.10.30.2-0.20.3-0.40.3-0.40.4-0.30.0-0.1-0.8
Delay discounting total patch changes 6 sec0.20.21.90.10.40.10.20.2-0.20.4-0.30.1-0.40.1-0.4-1.40.9-0.4
Delay discounting time to switch 0 sec1.42.13.1-1.4-1.4-1.61.01.7-1.71.7-1.7-0.2-1.70.4-1.7-0.61.7-1.7
Delay discounting water rate 0 sec0.81.32.51.51.31.2-0.2-1.41.6-1.41.30.91.30.51.40.1-0.71.2
Delay discounting water rate 12 sec0.71.01.80.80.91.0-0.6-1.21.2-1.01.10.11.3-0.11.01.2-1.31.2
Delay discounting water rate 18 sec2.83.66.21.92.12.1-1.1-2.22.3-2.42.10.42.5-0.22.41.3-1.42.2
Delay discounting water rate 24 sec0.20.30.60.80.40.5-0.1-0.70.7-0.50.60.50.70.10.5-0.1-0.30.6
Delay discounting water rate 6 sec0.91.32.60.70.91.0-0.8-1.31.3-1.31.20.01.4-0.21.31.6-1.51.3
Locomotor activity1.42.27.42.71.61.60.7-1.31.9-1.00.92.11.31.51.00.1-0.11.7
Locomotor testing distance0.61.02.81.71.11.00.5-0.91.3-0.60.61.40.91.10.6-0.20.01.4
Locomotor testing rearing1.01.53.41.11.61.2-0.3-1.51.5-1.11.10.61.40.41.1-1.90.51.8
Light reinforcement 10.00.10.4-0.7-0.2-0.4-0.10.1-0.30.2-0.1-0.4-0.3-0.0-0.20.3-0.20.2
Light reinforcement 20.30.42.1-0.7-0.6-0.3-0.5-0.1-0.1-0.10.2-0.7-0.1-0.60.11.4-1.10.4
Reaction time number correct0.30.42.30.60.60.30.5-0.30.5-0.1-0.00.80.40.80.1-1.50.60.9
Reaction time mean minus median0.60.71.70.61.11.3-1.1-0.60.6-1.00.7-0.80.9-1.01.00.9-0.50.4
Reaction time mean minus median AUC0.91.22.20.51.51.5-1.3-1.01.0-1.31.1-0.81.3-1.01.30.4-0.30.9
Reaction time num false alarms0.81.11.8-0.3-1.2-1.01.11.1-1.01.3-1.30.7-1.31.0-1.30.40.1-1.1
Reaction time num false alarms AUC1.11.62.9-0.6-1.4-1.21.11.6-1.41.7-1.60.4-1.70.8-1.70.50.2-1.3
Reaction time trials correct on left0.30.42.30.60.60.30.5-0.30.5-0.1-0.00.80.40.80.1-1.50.60.9
Reaction time trials on left0.30.42.10.70.60.30.5-0.30.5-0.1-0.00.80.40.80.1-1.50.60.9
Reaction time mean0.50.73.0-0.8-0.20.3-1.20.1-0.5-0.00.1-1.7-0.3-1.60.01.0-0.9-0.5
Reaction time mean AUC0.40.62.1-0.9-0.4-0.1-0.80.4-0.80.3-0.3-1.4-0.7-1.2-0.30.7-0.4-1.0
Median of all reaction times0.60.93.0-1.4-0.8-0.4-0.90.6-1.00.5-0.3-1.7-0.9-1.5-0.50.7-0.6-0.9
Reaction time omissions0.10.11.00.20.20.10.2-0.0-0.00.0-0.20.2-0.10.1-0.00.50.5-1.0
Reaction time false alarm rate1.01.42.5-0.8-1.4-1.20.81.4-1.41.4-1.30.0-1.60.5-1.41.2-0.2-1.4
Reaction time premature initiation rate0.50.62.0-1.4-0.8-1.00.10.7-0.90.4-0.4-0.6-0.7-0.0-0.4-1.10.5-1.4
Reaction time premature initiations0.30.42.8-0.9-0.2-0.60.20.3-0.40.2-0.2-0.2-0.30.3-0.2-1.70.9-0.7
Std. dev. reaction times0.30.41.3-0.00.50.7-0.9-0.1-0.0-0.30.2-1.00.1-1.00.31.2-0.5-0.2
Reaction time trials completed0.30.42.10.70.60.30.5-0.30.5-0.1-0.00.80.40.80.1-1.50.60.9
Reaction time trials AUC0.20.31.80.50.40.10.5-0.20.40.0-0.20.70.20.7-0.0-1.30.50.7
Social response proportion0.60.73.7-0.3-0.9-0.4-0.00.9-0.90.7-0.6-0.5-0.8-0.4-0.71.9-0.8-0.9
Social responses0.40.51.3-1.0-0.7-0.5-0.50.5-0.70.5-0.2-1.1-0.6-0.9-0.50.9-0.7-0.2
Social time0.50.61.6-0.8-0.9-0.3-0.60.5-0.80.5-0.5-1.3-0.4-1.0-0.51.2-1.1-0.6
Conditioned locomotion1.01.15.90.10.3-0.30.90.8-0.40.7-0.80.8-0.70.8-0.7-2.42.4-0.3
Cocaine response after cond. corrected0.30.41.10.41.10.60.0-0.50.7-0.70.40.40.70.30.7-0.60.80.5
Cocaine response after cond. not corrected0.60.61.60.91.30.80.2-0.71.0-0.90.50.81.00.70.90.00.70.8
Cocaine response before conditioning0.10.20.50.60.40.30.4-0.20.5-0.30.20.70.30.70.30.20.30.4
Saline control response2.33.06.11.72.02.1-1.2-2.12.1-2.01.90.02.1-0.72.00.1-0.92.5
Condit. Reinf. active minus inactive responses0.20.30.9-0.1-0.6-0.70.80.1-0.10.3-0.30.8-0.30.9-0.30.80.2-0.3
Condit. Reinf. active-inactive response ratio0.80.81.81.20.80.50.5-0.91.2-0.90.51.31.01.00.90.70.31.1
Condit. Reinf. active responses0.71.02.3-1.2-1.4-1.50.90.9-1.01.0-0.90.2-1.20.7-1.00.40.3-1.0
Condit. Reinf. inactive responses1.31.63.4-1.8-1.6-1.60.51.4-1.61.4-1.1-0.6-1.50.1-1.4-0.30.2-1.4
Condit. Reinf. lever presses0.40.64.6-0.6-1.1-0.80.10.1-0.30.3-0.1-0.2-0.30.0-0.32.1-1.0-0.2
Condit. Reinf. lever reinforcers received0.60.82.0-1.1-1.4-1.40.70.7-0.90.9-0.70.1-1.00.6-0.90.80.0-0.7
Pavlov. Cond. lever latency0.40.62.6-0.6-0.2-0.40.21.0-0.90.7-0.8-0.4-0.7-0.1-0.7-1.60.9-0.8
Pavlov. Cond. magazine entry latency1.21.43.00.60.61.1-1.4-1.21.0-1.21.4-0.81.2-1.31.21.2-1.71.0
Pavlov. Cond. change in total contacts1.31.83.21.41.31.4-0.6-1.81.8-1.61.60.51.60.01.61.1-0.91.6
Pavlov. Cond. index score0.50.62.80.60.10.5-0.5-0.90.8-0.70.9-0.00.7-0.30.71.7-1.40.7
Pavlov. Cond. latency score0.60.72.70.60.20.6-0.6-1.00.9-0.81.0-0.10.8-0.40.81.6-1.40.7
Pavlov. Cond. lever contacts0.50.73.40.40.10.5-0.5-1.00.8-0.70.9-0.10.7-0.30.71.8-1.40.8
Pavlov. Cond. magazine entry number0.50.61.60.2-0.1-0.41.20.7-0.40.6-0.91.1-0.61.3-0.6-0.81.2-0.6
Pavlov. Cond. intertrial magazine entries4.25.48.7-1.6-2.4-2.72.22.7-2.62.8-2.80.8-2.91.5-2.8-0.51.9-2.7
Pavlov. Cond. lever-magazine prob. diff.0.60.82.60.60.20.6-0.7-1.00.9-0.91.1-0.20.9-0.50.91.6-1.50.9
Pavlov. Cond. response bias0.50.72.10.00.10.4-0.8-0.90.7-0.81.0-0.50.8-0.70.81.4-1.30.9
Conditioned reinforcement - actives0.10.10.4-0.0-0.1-0.10.20.1-0.10.1-0.00.20.00.4-0.10.6-0.4-0.3
Conditioned reinforcement - inactives0.10.10.3-0.20.50.2-0.10.00.1-0.20.2-0.10.20.20.2-0.3-0.10.4
Conditioned locomotion0.30.30.80.10.50.4-0.5-0.30.4-0.80.7-0.20.8-0.40.80.6-0.40.9
Intermittent access intake day 1-15 change0.30.21.50.60.20.5-0.0-0.40.3-0.20.20.20.10.30.21.2-1.10.0
Intermittent access intake escalation0.20.20.80.40.30.4-0.2-0.50.4-0.30.40.10.20.10.30.9-0.9-0.0
Intermittent access intake escalation 20.50.51.7-0.6-0.8-0.50.00.5-0.70.6-0.5-0.5-0.8-0.1-0.61.3-0.8-0.9
Intermitt. access day 1 inactive lever presses0.91.02.30.71.41.3-1.0-1.01.0-0.91.0-0.50.9-0.90.9-1.00.11.5
Intermitt. access day 15 inactive lever presses0.50.52.1-0.80.00.2-1.2-0.30.0-0.50.6-1.40.3-1.50.50.3-0.70.5
Intermitt. access escalation Index0.30.31.1-0.20.1-0.40.70.6-0.30.5-0.60.6-0.21.0-0.5-0.60.8-0.0
Intermittent access day 1 total infusions0.20.30.80.20.60.5-0.5-0.10.3-0.80.5-0.20.9-0.40.80.2-0.00.5
Intermittent access day 15 total infusions0.30.30.80.20.80.5-0.4-0.50.6-0.90.7-0.00.9-0.00.90.2-0.30.5
Intermittent access terminal intake (last 3 days)0.50.51.60.20.50.6-0.7-0.50.5-0.80.7-0.40.9-0.30.81.3-1.20.4
Intermittent access total infusions0.20.30.7-0.00.60.5-0.6-0.20.2-0.70.6-0.40.9-0.40.70.2-0.30.3
Intermittent access day 1 locomotion0.40.40.90.60.90.7-0.4-0.30.5-0.80.70.00.9-0.40.8-0.40.30.5
Intermittent access day 15 total locomotion0.30.30.7-0.20.50.4-0.7-0.20.3-0.70.6-0.60.6-0.70.70.9-0.40.7
Intermittent access total locomotion0.40.40.80.50.90.8-0.7-0.20.4-0.80.6-0.40.8-0.70.80.4-0.20.6
Intermittent access standard deviation0.50.52.0-1.3-0.3-0.4-1.0-0.4-0.1-0.30.5-1.4-0.1-1.30.30.2-0.70.3
Cocaine induced anxiety0.80.92.1-1.4-1.4-1.0-0.40.7-1.10.7-0.5-1.2-0.6-1.0-0.71.4-0.8-0.8
Post-drug Anxiety0.40.51.5-1.2-1.1-0.7-0.70.1-0.60.2-0.0-1.2-0.1-1.0-0.20.5-0.6-0.3
Baseline Anxiety0.20.20.70.50.40.4-0.2-0.70.7-0.60.50.20.60.10.6-0.4-0.10.9
Lifetime Intake0.20.20.70.10.40.4-0.5-0.10.2-0.70.5-0.30.9-0.30.70.6-0.30.1
Incentive Sensitization - Responses0.60.61.6-1.3-0.3-0.4-1.0-0.80.3-0.80.8-1.10.6-0.80.80.3-0.90.8
Incentive Sensitization - Breakpoint0.70.71.4-1.2-0.3-0.3-0.9-0.80.3-0.80.9-1.10.6-0.80.80.8-1.10.8
Progressive ratio test 1 active lever presses0.20.20.60.80.60.60.1-0.20.3-0.30.30.50.50.20.30.20.4-0.4
Progressive ratio test 1 breakpoint0.40.41.11.00.90.9-0.2-0.50.6-0.70.60.40.80.10.70.30.1-0.1
Progressive ratio test 1 inactive lever presses0.20.20.90.90.50.60.1-0.10.3-0.20.30.50.30.10.2-0.50.3-0.5
Progressive ratio test 2 active lever presses0.30.30.70.30.20.3-0.4-0.80.6-0.80.8-0.00.7-0.20.80.6-0.70.1
Progressive ratio test 2 breakpoint0.10.10.30.30.10.2-0.1-0.40.4-0.50.40.20.50.10.50.4-0.5-0.0
Progressive ratio test 2 inactive lever presses0.10.10.6-0.3-0.4-0.40.20.3-0.40.4-0.50.0-0.40.1-0.4-0.40.2-0.7
Total sessions with >9 infusions0.20.20.50.70.40.50.0-0.10.3-0.40.20.30.60.20.40.7-0.3-0.2
Short access day 1 total inactive lever presses0.40.53.4-0.20.80.3-0.10.4-0.40.3-0.4-0.3-0.0-0.3-0.3-1.81.4-0.6
Short access day 10 total inactive lever presses0.91.02.3-0.11.11.1-1.5-1.00.7-0.91.0-1.30.7-1.50.9-0.5-0.61.4
Short access day 1 total infusions0.10.10.50.10.70.4-0.00.3-0.0-0.2-0.00.00.50.20.2-0.10.50.0
Short access day 10 total infusions0.60.61.40.90.90.9-0.5-0.50.7-1.11.00.11.2-0.21.10.6-0.60.5
Short access total infusions0.10.20.60.40.70.6-0.20.00.1-0.50.30.00.80.00.50.40.1-0.0
Short access day 1 locomotion0.80.94.20.91.20.50.80.10.3-0.10.01.20.21.10.1-1.72.1-0.1
Short access day 10 total locomotion1.21.33.00.71.31.5-1.5-1.00.9-1.21.2-1.11.0-1.71.20.7-0.50.9
Short access total locomotion1.01.02.71.71.61.5-0.3-0.81.1-1.21.00.61.2-0.11.2-0.00.10.7
Compulsive drug intake3.13.17.8-0.1-0.9-1.62.31.3-1.01.6-1.61.9-1.62.2-1.6-2.82.6-1.3
One hour access (0.3 mA shock)0.30.41.0-0.3-0.6-0.80.80.7-0.60.4-0.50.6-0.50.9-0.40.00.4-1.0
One hour access (shock baseline)0.50.62.5-0.8-0.7-0.3-0.6-0.0-0.3-0.20.2-1.00.1-0.70.21.6-1.4-0.6
Number of responses in last shaping day0.50.51.81.31.31.10.1-0.30.7-0.50.40.70.50.40.5-0.90.30.5
Context. condit. distance diff. score0.50.62.5-1.1-0.4-0.1-1.1-0.2-0.3-0.20.3-1.6-0.0-1.30.20.9-1.1-0.2
Locomotion velocity, session 12.32.45.31.22.31.9-1.1-1.81.9-1.81.8-0.11.9-0.41.8-0.00.02.1
Locomotion distance, session 14.55.810.71.73.32.9-1.9-3.02.9-2.92.9-0.42.8-1.02.90.2-0.43.0
Locomotion velocity, session 25.26.113.21.43.23.0-2.5-2.82.7-2.82.8-1.12.8-1.72.80.2-0.83.6
Locomotion distance, session 25.57.915.41.93.93.4-2.4-3.43.3-3.33.3-0.63.3-1.33.3-0.2-0.53.8
Locomotion velocity, session 30.70.82.8-1.30.80.3-1.3-0.70.2-0.50.7-1.70.5-1.30.5-0.80.60.8
Locomotion distance, session 30.20.20.9-0.7-0.2-0.1-0.7-0.2-0.20.10.3-1.00.0-0.8-0.10.4-0.5-0.2
Stereotopy head waving bouts, day 30.20.20.5-0.7-0.6-0.70.10.3-0.40.4-0.4-0.2-0.30.1-0.40.4-0.60.1
Stereotopy head waving duration, day 30.10.20.70.20.60.3-0.1-0.40.5-0.40.30.20.50.20.4-0.40.10.8
Locomotion velocity, session 72.83.16.31.02.52.0-1.3-2.12.1-2.02.2-0.22.0-0.62.0-1.60.42.1
Locomotion distance, session 70.50.61.21.11.10.9-0.0-0.81.0-0.70.80.70.80.40.7-1.00.40.8
Stereotopy head waving bouts, day 72.12.48.4-2.9-1.6-1.8-0.31.4-1.91.5-1.3-1.9-1.7-1.0-1.5-0.80.4-1.3
Stereotopy head waving duration, day 72.12.68.4-2.9-1.6-2.00.01.6-2.01.6-1.5-1.6-1.8-0.6-1.6-1.00.9-1.5
Locomotion velocity, session 82.42.96.40.02.41.9-2.1-1.91.6-1.71.8-1.61.7-1.71.7-0.40.12.5
Locomotion distance, session 81.92.84.80.11.91.8-2.2-2.01.5-1.82.0-1.71.6-1.81.80.3-0.92.1
Degree of sensitization distance0.80.82.31.51.00.80.5-0.61.0-0.70.41.40.60.90.7-0.90.60.8
Degree of sensitization stereotypy1.51.76.7-2.6-1.1-1.0-1.20.7-1.30.7-0.5-2.5-0.9-1.8-0.7-0.3-0.3-0.6
Condit. Reinf. active minus inactive responses0.30.32.90.2-0.3-0.0-0.2-0.40.3-0.30.40.00.3-0.30.31.7-0.70.4
Condit. Reinf. active-inactive response ratio2.42.64.21.31.31.6-1.3-2.01.9-1.92.0-0.11.9-0.91.91.9-1.51.6
Condit. Reinf. active responses0.10.10.5-0.3-0.3-0.40.20.0-0.10.2-0.00.1-0.10.1-0.20.70.10.4
Condit. Reinf. inactive responses1.51.82.8-1.2-1.2-1.61.31.6-1.51.7-1.60.4-1.51.0-1.7-1.01.3-0.8
Incentive salience index mean0.70.82.90.20.30.5-0.9-1.00.8-0.81.1-0.50.8-1.00.81.7-1.20.9
Condit. Reinf. lever presses1.72.33.80.81.71.7-1.7-1.91.6-1.71.9-0.81.7-1.41.70.3-1.01.8
Time in familiar zone, hab. session 14.84.56.5-0.6-2.1-2.22.52.3-2.02.5-2.51.6-2.32.2-2.5-1.71.5-2.4
Time in novel zone, hab. session 13.83.75.61.11.82.1-2.0-2.01.9-2.32.3-0.92.2-1.62.31.6-1.62.4
Total zone transitions, hab. session 13.24.59.61.03.12.5-1.8-2.62.4-2.42.6-0.62.2-1.12.4-1.70.52.8
Total locomotion distance, hab. session 12.53.68.31.82.92.3-0.9-2.12.3-2.12.10.51.9-0.12.1-2.01.02.2
Locomotion velocity, hab. session 13.04.310.11.63.22.4-1.2-2.52.5-2.22.40.22.0-0.42.2-2.51.22.3
Time in familiar zone, hab. session 20.40.50.8-0.2-0.8-0.80.90.6-0.50.7-0.80.7-0.40.9-0.7-0.70.0-0.7
Time in novel zone, hab. session 22.02.02.80.91.41.7-1.5-1.51.4-1.71.6-0.71.4-1.31.71.5-1.11.5
Total zone transitions, hab. session 23.34.38.81.23.02.4-1.7-2.62.5-2.42.5-0.52.3-0.92.4-0.70.12.8
Total locomotion distance, hab. session 22.33.17.31.82.72.1-0.6-2.12.3-1.91.90.81.80.31.9-1.30.82.2
Locomotion velocity, hab. session 22.33.17.61.62.82.1-0.7-2.12.2-1.81.90.61.80.21.8-1.61.02.2
Novel to familiar place preference ratio0.10.10.80.70.10.40.1-0.00.2-0.00.20.40.10.10.00.9-0.70.1
Novelty place preference0.30.31.31.00.20.6-0.1-0.30.5-0.30.40.40.30.10.31.2-1.00.4
Time in novel zone, NPP test0.70.72.21.30.40.9-0.3-0.60.8-0.70.80.50.7-0.00.71.5-1.40.7
Total zone transitions, NPP test8.011.419.92.84.54.2-2.6-4.24.1-4.04.0-0.33.8-1.34.00.5-1.34.4
Total locomotion distance, NPP test5.47.415.92.54.03.3-1.5-3.33.5-3.13.20.53.0-0.33.1-1.40.13.5
Locomotion velocity, NPP test3.95.613.02.13.62.8-1.2-2.93.0-2.62.70.52.5-0.22.6-1.60.53.0
Pavlov. Cond. lever latency0.81.01.9-0.4-0.8-1.11.31.4-1.01.0-1.20.8-1.01.2-1.0-0.61.2-0.8
Pavlov. Cond. magazine entry latency1.62.04.00.10.81.1-1.9-1.81.2-1.62.0-1.41.6-1.81.60.3-1.60.9
Pavlov. Cond. change in total contacts0.60.71.7-0.50.10.3-1.2-0.80.3-0.50.9-1.20.6-1.30.50.9-1.30.6
Pavlov. Cond. index score1.31.72.80.30.81.1-1.7-1.71.2-1.41.7-1.11.4-1.61.40.7-1.60.9
Pavlov. Cond. latency score1.41.83.30.61.01.3-1.6-1.81.4-1.51.8-0.91.5-1.41.50.7-1.61.0
Pavlov. Cond. lever contacts1.01.22.10.50.81.1-1.3-1.51.1-1.11.4-0.81.1-1.21.10.8-1.40.7
Pavlov. Cond. magazine entry number0.91.12.50.0-0.1-0.61.41.2-0.71.0-1.31.1-1.01.5-1.0-0.71.6-0.8
Pavlov. Cond. intertrial magazine entries2.63.15.6-1.4-2.4-2.31.72.1-2.02.1-2.10.5-2.11.2-2.10.70.3-1.6
Pavlov. Cond. lever-magazine prob. diff.1.21.42.80.10.60.9-1.7-1.50.9-1.21.5-1.31.2-1.71.20.7-1.60.7
Pavlov. Cond. response bias0.60.72.3-0.7-0.20.1-1.3-0.70.2-0.50.9-1.40.5-1.50.50.6-1.30.2
Bone: apparent density0.71.12.6-1.0-1.6-1.40.71.0-1.21.2-1.00.0-1.10.3-1.20.5-0.0-1.6
Bone surface1.42.45.1-1.8-2.3-2.00.61.8-2.01.8-1.6-0.6-1.70.1-1.81.0-0.5-1.8
Bone volume0.81.32.7-1.3-1.7-1.50.61.3-1.41.3-1.1-0.3-1.30.2-1.30.5-0.1-1.5
Bone: connectivity density1.11.73.1-1.4-1.7-1.70.81.4-1.61.5-1.3-0.2-1.50.2-1.5-0.40.6-1.8
Bone: cortical apparent density0.20.21.40.60.50.40.1-0.10.3-0.1-0.30.20.0-0.20.1-0.71.20.7
Bone: cortical area2.03.05.70.21.41.7-2.4-2.01.5-1.92.2-1.71.8-2.21.91.0-1.81.4
Bone: cortical porosity0.70.81.6-0.20.40.6-1.3-0.80.5-0.91.0-1.10.7-1.20.91.1-1.10.5
Bone: cortical porosity0.80.92.2-0.30.50.7-1.4-0.90.5-0.91.1-1.30.7-1.50.90.8-1.00.4
Bone: cortical thickness0.91.53.50.01.21.2-1.8-1.30.9-1.31.4-1.41.2-1.91.30.2-1.00.7
Bone: cortical thickness0.10.11.20.2-0.10.1-0.2-0.20.1-0.10.10.00.1-0.20.11.1-0.7-0.1
Bone: cortical tissue density0.20.21.50.60.50.40.1-0.10.3-0.1-0.30.20.0-0.20.1-0.71.20.7
Bone: elastic displacement2.22.53.91.61.62.0-1.4-2.01.8-1.81.8-0.21.8-1.01.80.9-1.31.3
Bone: elastic work1.11.42.81.11.01.2-1.0-1.71.5-1.51.6-0.11.5-0.71.50.2-0.81.1
Bone: endosteal estimation0.51.03.30.11.00.8-0.9-1.11.0-1.11.4-0.51.1-0.51.10.2-0.51.8
Bone: endosteal perimeter1.73.46.20.51.61.8-2.2-2.11.7-2.02.5-1.42.0-1.82.01.2-1.82.1
Bone: final force0.10.10.3-0.30.0-0.1-0.4-0.50.3-0.40.5-0.30.4-0.30.40.3-0.30.2
Bone: final moment0.10.20.5-0.00.10.1-0.3-0.70.5-0.50.7-0.10.6-0.20.50.5-0.40.3
Bone: marrow area0.61.23.90.31.11.0-1.0-1.21.2-1.21.5-0.51.3-0.61.20.3-0.62.0
Bone: maximum diameter3.56.511.10.92.82.8-3.0-3.02.6-3.03.3-1.82.9-2.43.00.4-1.62.5
Bone: maximum force0.20.40.8-0.20.20.3-0.9-0.60.4-0.60.7-0.80.7-0.90.60.9-0.70.7
Bone: maximum moment0.40.61.10.10.40.5-0.9-0.80.6-0.81.0-0.61.0-0.80.81.1-0.90.9
Bone: minimum diameter0.30.62.5-0.6-0.4-0.0-1.0-0.50.1-0.40.7-1.10.4-1.10.41.1-1.60.0
Bone: periosteal estimation1.32.64.70.11.51.5-2.0-1.91.5-1.82.2-1.31.8-1.61.80.6-1.22.0
Bone: periosteal perimeter2.44.06.90.21.61.8-2.6-2.31.7-2.22.6-1.92.2-2.32.20.7-1.92.0
Bone: post-yield work0.50.62.2-1.1-1.0-0.6-0.40.8-0.90.5-0.4-1.1-0.4-0.7-0.51.5-0.80.1
Bone: stiffness0.40.72.0-1.4-0.8-0.6-0.70.4-0.70.3-0.2-1.4-0.2-1.1-0.31.3-0.90.0
Bone: tissue strength0.10.10.40.50.20.10.3-0.10.3-0.20.00.50.20.40.20.40.10.6
Bone: trabecular number1.42.14.6-1.6-2.1-1.90.71.5-1.81.7-1.4-0.5-1.60.0-1.70.40.1-2.2
Bone: trabecular spacing0.40.51.31.01.10.80.2-0.30.7-0.50.30.60.40.40.5-0.81.00.8
Bone: trabecular thickness0.60.72.31.20.70.40.8-0.60.9-0.50.41.50.81.20.5-0.80.80.4
Bone: trabecular tissue density1.52.03.41.71.81.8-0.6-1.61.8-1.71.50.51.7-0.11.70.3-0.11.8
Breakpoint value in progressive ratio session0.60.61.9-0.9-1.4-1.10.31.0-1.00.6-0.7-0.3-1.0-0.3-0.6-0.30.1-1.0
Distance traveled before self-admin2.32.43.91.41.91.9-1.2-1.71.8-2.01.9-0.21.9-0.82.00.9-1.01.5
Distance traveled after self-admin0.20.21.31.10.20.60.1-0.30.4-0.20.10.50.20.10.20.5-0.7-0.2
Delta time in closed arm before/after self-admin1.11.14.7-1.8-0.7-0.5-1.30.1-0.70.30.1-2.2-0.5-2.1-0.3-0.9-0.0-0.2
Delta time in open arm before/after self-admin0.70.74.60.30.40.10.70.6-0.30.3-0.60.6-0.40.8-0.3-2.11.4-0.8
Diff in mean of infusions in LGA sessions0.40.51.6-1.1-1.2-1.00.10.7-0.70.5-0.4-0.5-0.7-0.0-0.50.2-0.6-0.7
Extinction: sum of active levers before priming0.30.30.80.90.10.5-0.2-0.70.7-0.40.60.30.2-0.40.4-0.8-0.3-0.0
Active lever presses in extinction session 60.20.20.70.80.40.7-0.3-0.40.5-0.50.40.00.3-0.40.50.1-0.40.4
Delta distance traveled before/after self-admin1.41.52.9-0.1-1.3-1.01.11.2-1.21.6-1.60.6-1.50.6-1.6-1.00.6-1.7
Delta ambulatory time before/after self-admin1.01.11.90.1-0.8-0.71.11.0-0.91.4-1.40.7-1.30.7-1.4-1.10.9-1.2
Time in closed arm before self-admin1.31.56.42.21.10.81.5-0.00.9-0.3-0.22.50.72.40.30.30.50.3
Time in closed arm after self-admin0.40.41.00.80.90.8-0.3-0.50.7-0.60.50.21.0-0.00.60.1-0.30.9
Time in open arm before self-admin0.60.61.7-1.3-1.3-1.1-0.20.2-0.80.9-0.4-0.8-0.8-0.8-0.9-0.1-0.2-0.6
Time in open arm after self-admin1.41.62.9-1.3-1.3-1.30.61.3-1.41.4-1.3-0.4-1.6-0.0-1.4-1.61.0-1.7
Sum of active levers in priming session hrs 5-61.41.42.60.70.71.0-1.0-1.31.3-1.61.6-0.41.3-0.91.60.6-1.41.3
Time to tail flick, vehicle, before self-admin0.20.21.7-0.20.3-0.00.2-0.00.1-0.00.10.1-0.10.40.0-1.30.70.2
Time to tail flick, vehicle, after self-admin0.70.81.51.11.21.1-0.3-0.91.1-0.90.90.51.10.10.9-1.10.00.9
Time to tail flick, test, before self-admin0.50.51.6-1.3-0.8-1.00.20.9-1.00.7-0.8-0.5-0.60.0-0.70.2-0.1-0.9
Time to tail flick, test, after self-admin0.30.30.80.80.50.5-0.0-0.80.8-0.30.50.60.50.20.3-0.9-0.40.7
Delta time to tail flick, vehicle, before/after SA0.50.51.21.10.91.0-0.4-0.70.8-0.80.70.21.0-0.30.80.5-0.40.6
Delta time to tail flick, test, before/after SA0.70.72.31.50.90.80.4-0.71.0-0.40.41.20.50.80.4-1.00.30.7
Ambulatory time before self-admin2.12.23.51.21.71.8-1.2-1.61.7-1.91.8-0.21.8-0.71.90.8-1.11.7
Ambulatory time after self-admin0.20.21.71.30.40.70.1-0.30.5-0.30.10.60.20.10.30.4-0.50.1
Total heroin consumption0.60.73.6-0.7-1.3-0.6-0.7-0.2-0.0-0.50.5-0.90.3-1.00.50.8-1.90.4
Area under the delay curve0.80.81.6-1.3-1.1-1.10.20.9-1.21.0-0.8-0.6-1.0-0.0-1.00.9-0.3-1.3
Delay disc. indifference point, 0s delay1.92.13.7-1.9-1.8-1.90.81.6-1.81.6-1.5-0.4-1.70.3-1.6-0.00.6-1.8
Delay disc. indifference point, 16s delay0.20.21.0-0.3-0.2-0.0-0.5-0.30.0-0.10.4-0.6-0.1-0.50.11.0-0.9-0.0
Delay disc. indifference point, 2s delay0.30.32.6-0.50.20.1-0.5-0.20.0-0.20.4-0.50.3-0.20.21.6-0.80.5
Delay disc. indifference point, 24s delay0.20.20.8-0.3-0.6-0.40.10.4-0.50.3-0.2-0.2-0.5-0.1-0.30.9-0.2-0.6
Delay disc. indifference point, 4s delay1.61.72.9-1.7-0.9-1.40.81.6-1.61.5-1.4-0.3-1.50.6-1.5-0.51.3-1.7
Delay disc. indifference point, 8s delay0.90.91.9-0.9-1.4-0.90.10.8-1.10.9-0.8-0.5-0.9-0.2-0.91.3-1.1-1.4
Delay discount exponential model param0.70.71.41.10.90.9-0.3-0.91.1-0.90.80.41.0-0.10.9-0.90.11.2
Delay discount hyperbolic model param0.60.61.31.10.80.9-0.2-0.91.0-0.90.70.50.9-0.10.9-0.90.21.0
Fecal boli incidents, locomotor time 10.70.72.00.31.41.0-0.7-1.01.0-1.01.0-0.21.2-0.21.00.20.10.6
Change in fecal boli incidents, locomotor task0.60.51.61.30.90.80.2-0.81.0-0.50.51.00.60.70.5-0.70.10.4
Time >=10cm from walls, locomotor time 10.40.40.80.20.50.7-0.8-0.90.7-0.70.8-0.50.6-0.70.70.5-0.70.7
Bouts of movement, locomotor time 10.10.10.6-0.1-0.2-0.1-0.00.2-0.20.1-0.3-0.1-0.0-0.1-0.10.8-0.2-0.4
Total resting periods, locomotor time 10.10.10.4-0.10.10.2-0.3-0.1-0.0-0.20.0-0.30.1-0.40.20.7-0.3-0.4
Rest time, locomotor task time 12.22.45.6-0.40.71.2-2.4-1.60.9-1.41.6-2.11.3-2.31.41.5-2.20.7
Distance moved, locomotor task time 10.90.93.80.30.2-0.41.30.6-0.20.8-0.71.3-0.61.3-0.8-1.62.00.2
Vertical activity count, locomotor time 10.80.81.5-0.8-1.0-1.10.71.2-1.11.2-1.20.1-0.90.2-1.2-0.51.0-0.1
Time >=10cm from walls, locomotor time 20.70.72.5-1.4-1.0-0.6-0.90.4-0.70.2-0.2-1.6-0.4-1.2-0.21.1-1.0-0.0
Bouts of movement, locomotor time 20.40.51.00.20.60.6-0.7-0.70.6-0.70.8-0.40.9-0.70.7-0.7-0.01.0
Total resting periods, locomotor time 20.40.51.00.30.50.6-0.8-0.70.6-0.80.9-0.50.9-0.90.8-0.4-0.31.0
Rest time, locomotor task time 20.10.10.50.20.10.4-0.4-0.30.2-0.40.3-0.30.3-0.50.40.6-0.7-0.1
Distance moved, locomotor task time 20.91.12.9-1.7-1.0-1.40.41.1-1.21.2-1.0-0.5-1.20.1-1.2-0.51.2-0.2
Vertical activity count, locomotor time 20.91.02.5-1.6-1.4-1.40.11.1-1.31.2-1.0-0.8-0.9-0.4-1.2-0.10.4-0.1
Weight adjusted by age1.92.24.92.21.31.5-0.5-1.92.0-1.61.81.01.6-0.01.6-0.9-0.71.6
Seeking ratio, delayed vs. immediate footshock0.40.51.1-1.0-0.5-0.5-0.30.5-0.80.6-0.3-0.9-1.0-0.7-0.6-0.80.2-1.0
Locomotion in novel chamber1.11.42.4-1.5-1.3-1.60.71.5-1.51.4-1.5-0.2-1.30.3-1.40.00.8-0.8
Locomotion in novel chamber post-restriction0.91.13.4-0.2-0.8-0.91.21.2-0.91.1-1.20.9-0.71.3-1.11.90.3-0.8
Progressive ratio1.31.52.70.91.51.5-1.1-1.61.4-1.51.6-0.31.4-0.71.50.5-0.91.1
Food seeking constrained by brief footshock0.60.83.5-1.10.20.3-1.5-0.1-0.2-0.60.6-1.90.5-1.70.60.3-0.50.1
Seeking ratio, punishment vs. effort0.60.82.4-1.6-1.0-1.1-0.11.1-1.20.8-0.8-1.0-0.7-0.6-0.8-0.30.3-0.6
Run reversals in cocaine runway, females0.70.72.61.10.60.21.1-0.20.5-0.2-0.01.60.21.40.2-1.21.30.2
Run reversals in cocaine runway, males1.61.55.6-0.9-0.20.4-1.8-0.60.1-0.70.9-2.00.6-2.00.71.5-2.40.3
Latency to leave start box in cocaine runway2.32.64.2-1.5-2.1-2.01.11.9-1.91.8-2.0-0.1-1.90.2-1.8-1.01.3-1.7
Latency to leave start box in cocaine runway, F1.31.52.3-0.2-1.0-1.21.51.2-1.01.3-1.41.1-1.41.2-1.3-1.21.5-1.3
Latency to leave start box in cocaine runway, M2.42.35.7-2.4-2.0-1.9-0.01.7-2.01.4-1.6-1.4-1.5-1.0-1.4-0.50.6-1.3
Cd content in liver1.21.33.4-1.8-1.2-0.8-0.90.7-1.20.7-0.6-1.8-0.7-1.3-0.71.2-1.4-0.8
Co content in liver0.40.51.2-0.40.30.4-1.1-0.70.4-0.70.8-1.10.6-1.10.7-0.3-0.60.7
Cu content in liver1.51.84.8-1.6-2.2-1.70.31.6-1.81.4-1.2-0.7-1.5-0.3-1.40.9-0.6-1.3
Fe content in liver1.01.23.3-1.0-1.8-1.30.50.9-1.10.9-0.9-0.2-1.00.3-0.91.7-1.3-0.9
K content in liver1.51.510.30.21.70.7-0.1-0.50.7-0.60.90.30.60.30.6-3.22.31.1
Mg content in liver0.60.75.1-0.01.00.5-0.2-0.20.3-0.40.6-0.10.3-0.10.4-2.21.50.6
Mn content in liver1.51.73.4-0.11.61.2-1.4-1.51.2-1.51.8-0.91.4-0.91.5-1.50.31.6
Na content in liver0.70.84.6-0.10.4-0.30.70.3-0.00.1-0.10.8-0.10.9-0.1-2.12.20.3
Rb content in liver0.10.10.50.30.1-0.10.5-0.00.10.00.00.6-0.00.7-0.0-0.30.4-0.0
Se content in liver1.31.62.4-1.0-1.2-1.61.41.5-1.31.4-1.40.7-1.41.2-1.4-0.71.1-1.3
Sr content in liver0.50.40.9-0.9-0.4-0.80.50.7-0.70.7-0.6-0.0-0.70.4-0.7-0.80.7-0.6
Zn content in liver0.10.10.5-0.00.2-0.00.20.1-0.1-0.00.10.20.00.30.0-0.70.7-0.4