Hub : Genes

Rdh11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000054770 0.22 0.08 0.0e+00 0.14 0.17 0.17 0.17 6.1e-15 5.0e-18 3.6e-18 3.7e-18
2 Brain gene expression ENSRNOG00000054770 0.04 0.03 2.5e-03 0.05 0.03 0.03 0.04 3.5e-05 1.4e-03 6.7e-04 1.2e-04
3 Liver intron excision ratio chr6:97990102:97991925 0.03 0.02 9.3e-03 0.02 0.01 0.01 0.02 9.5e-04 1.3e-02 1.2e-02 3.9e-03
4 PL alternative TSS ENSRNOT00000085927 0.06 0.04 1.3e-03 0.02 0.02 0.02 0.02 9.0e-03 1.1e-02 2.1e-02 1.2e-02
5 PL alternative TSS ENSRNOT00000105155 0.06 0.04 6.9e-03 0.02 0.01 0.01 0.01 2.0e-02 2.8e-02 4.9e-02 2.3e-02
6 PL alternative TSS ENSRNOT00000085927 0.05 0.03 5.2e-03 0.03 0.02 0.02 0.03 2.7e-03 7.8e-03 7.9e-03 3.2e-03
7 PL alternative TSS ENSRNOT00000105155 0.06 0.04 3.4e-03 0.02 0.02 0.02 0.02 1.1e-02 1.1e-02 8.3e-03 8.3e-03
8 PL isoform ratio ENSRNOT00000105155 0.06 0.04 5.9e-03 0.01 0.02 0.02 0.02 2.7e-02 2.1e-02 1.5e-02 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.72.37.62.80.6-1.41.0-1.50.8-1.5-1.5
BMI without tail1.12.37.12.7-0.4-0.11.4-1.41.4-1.4-1.9
Body weight2.08.619.74.4-1.8-2.03.3-1.63.5-1.6-3.8
Epididymis fat weight0.20.51.31.1-0.6-0.00.80.00.90.0-0.9
Glucose1.01.53.0-1.70.91.0-1.40.6-1.40.61.5
Heart weight1.62.23.51.3-0.71.91.9-1.21.8-1.2-1.7
Left kidney weight0.41.02.7-0.7-1.7-1.0-0.01.4-0.31.40.4
Right kidney weight0.61.73.4-0.9-1.6-1.2-0.81.8-0.81.80.9
Tail length1.03.06.72.0-2.6-0.41.90.12.30.1-2.1
Length with tail1.03.66.52.0-2.5-1.81.90.22.50.2-2.2
Length without tail0.71.56.01.1-1.0-2.41.00.31.20.3-1.1
Liver weight, left0.60.94.50.10.92.10.2-1.00.2-1.0-0.2
Liver weight, right0.40.71.5-1.0-0.8-0.2-0.51.2-0.31.20.6
Parametrial fat weight0.40.83.3-0.2-1.8-1.10.21.00.51.0-0.2
Retroperitoneal fat weight0.51.52.81.21.0-0.30.8-1.71.2-1.7-1.2
Intraocular pressure1.72.34.90.02.0-1.3-2.20.5-2.20.51.7
Extensor digitorum longus weight0.31.04.12.0-0.1-0.40.8-0.51.0-0.5-1.4
Soleus weight1.23.65.92.0-2.3-1.62.4-0.42.4-0.4-2.4
Tibialis anterior weight3.110.626.25.1-0.8-1.33.5-2.63.6-2.6-4.2
Tibia length0.51.42.5-0.6-0.3-1.0-1.31.6-1.31.61.2
Number of licking bursts2.53.05.9-2.41.51.4-2.00.6-2.00.62.2
Food consumed during 24 hour testing period0.20.20.50.7-0.1-0.60.2-0.30.4-0.3-0.5
Times rat made contact with spout1.21.32.51.2-1.1-0.11.5-0.61.5-0.6-1.6
Mean time between licks in bursts2.23.06.9-2.60.5-0.2-1.91.5-2.01.52.2
Mean num. licks in bursts3.74.57.72.8-2.0-1.52.6-0.72.5-0.7-2.8
Std. dev. time between licks in bursts0.70.81.7-1.3-0.8-0.5-0.41.1-0.51.10.8
Water consumed over 24 hours1.51.83.51.90.60.21.1-1.61.2-1.6-1.5
Indifference point 0 sec2.64.38.22.9-0.12.51.9-1.92.1-1.9-2.2
Indifference point AUC0.30.30.60.40.40.70.6-0.80.3-0.8-0.4
Indifference point function ln k0.30.40.80.9-0.10.50.6-0.50.6-0.5-0.7
Indifference point function log k0.30.40.80.9-0.10.50.6-0.50.6-0.5-0.7
Delay discounting total patch changes 0 sec2.84.58.52.90.22.71.8-2.12.0-2.1-2.2
Delay discounting total patch changes 12 sec0.91.23.01.7-0.40.81.2-0.71.1-0.7-1.3
Delay discounting total patch changes 18 sec2.83.76.92.60.11.71.9-1.82.0-1.8-2.3
Delay discounting total patch changes 24 sec1.11.35.82.4-0.30.61.0-0.51.1-0.5-1.3
Delay discounting total patch changes 6 sec1.11.73.41.70.11.81.2-1.21.2-1.2-1.3
Delay discounting time to switch 0 sec2.03.16.3-1.8-1.1-1.8-1.22.5-1.12.51.3
Delay discounting water rate 0 sec2.03.37.32.70.80.81.3-2.31.4-2.3-1.8
Delay discounting water rate 12 sec1.42.14.11.90.91.10.8-2.00.9-2.0-1.2
Delay discounting water rate 18 sec0.81.14.12.00.4-1.10.5-1.00.6-1.0-0.9
Delay discounting water rate 24 sec3.04.19.23.01.50.51.3-2.71.4-2.7-1.9
Delay discounting water rate 6 sec1.82.75.52.3-0.90.71.9-1.31.9-1.3-2.0
Locomotor activity1.11.83.81.9-0.1-1.71.4-0.81.4-0.8-1.5
Locomotor testing distance0.50.91.81.30.3-1.00.9-0.81.0-0.8-1.0
Locomotor testing rearing0.91.42.91.2-0.5-0.71.5-0.91.7-0.9-1.6
Light reinforcement 11.52.85.72.4-0.1-1.12.0-1.61.6-1.6-1.9
Light reinforcement 20.20.30.70.40.4-0.60.5-0.80.1-0.8-0.2
Reaction time number correct1.21.73.50.11.8-1.1-1.90.0-1.80.01.4
Reaction time mean minus median0.20.21.2-0.50.41.1-0.30.1-0.20.10.2
Reaction time mean minus median AUC0.20.31.7-0.10.71.3-0.1-0.4-0.0-0.4-0.0
Reaction time num false alarms0.40.52.10.11.4-0.9-0.7-0.4-0.5-0.40.5
Reaction time num false alarms AUC0.50.62.20.51.5-1.2-0.7-0.5-0.5-0.50.3
Reaction time trials correct on left1.21.73.50.11.8-1.1-1.90.0-1.80.01.4
Reaction time trials on left1.11.63.70.11.9-0.9-1.8-0.1-1.7-0.11.3
Reaction time mean1.31.87.20.3-0.02.71.4-1.01.4-1.0-1.3
Reaction time mean AUC1.31.86.80.30.12.61.3-1.01.3-1.0-1.3
Median of all reaction times1.72.47.90.6-0.12.81.7-1.11.6-1.1-1.6
Reaction time omissions1.31.77.60.31.32.80.3-1.30.3-1.3-0.5
Reaction time false alarm rate0.20.20.30.50.5-0.40.4-0.60.5-0.6-0.5
Reaction time premature initiation rate0.71.03.10.9-1.5-1.80.70.40.60.4-0.8
Reaction time premature initiations0.50.74.41.0-0.3-2.1-0.30.3-0.40.3-0.1
Std. dev. reaction times0.60.84.7-0.40.72.20.2-0.60.3-0.6-0.2
Reaction time trials completed1.11.63.70.11.9-0.9-1.8-0.1-1.7-0.11.3
Reaction time trials AUC1.21.74.70.22.2-0.7-1.8-0.3-1.8-0.31.3
Social response proportion0.30.30.8-0.2-0.90.10.7-0.30.7-0.3-0.5
Social responses2.12.85.91.40.81.11.4-2.41.4-2.4-1.6
Social time1.52.05.7-2.40.31.2-1.41.0-1.41.01.6
Conditioned locomotion1.51.82.5-1.5-0.1-0.2-1.51.6-1.61.61.6
Cocaine response after cond. corrected2.32.64.2-1.50.5-1.8-2.11.3-2.01.31.9
Cocaine response after cond. not corrected1.21.42.6-0.60.7-1.6-1.60.6-1.60.61.2
Cocaine response before conditioning1.11.43.01.70.30.71.0-1.31.0-1.3-1.4
Saline control response0.40.51.00.90.70.80.0-1.00.3-1.0-0.5
Condit. Reinf. active minus inactive responses3.44.27.72.22.52.20.7-2.80.7-2.8-1.2
Condit. Reinf. active-inactive response ratio1.71.72.71.51.71.60.5-1.60.6-1.6-0.8
Condit. Reinf. active responses2.73.76.42.21.21.91.4-2.51.5-2.5-1.8
Condit. Reinf. inactive responses0.30.30.50.3-0.30.40.6-0.70.7-0.7-0.7
Condit. Reinf. lever presses1.92.74.12.0-0.71.12.0-1.32.0-1.3-2.0
Condit. Reinf. lever reinforcers received3.04.27.32.31.31.91.5-2.71.5-2.7-1.8
Pavlov. Cond. lever latency1.62.23.2-1.80.5-1.0-1.71.5-1.81.51.7
Pavlov. Cond. magazine entry latency1.01.11.70.90.1-0.41.2-1.31.3-1.3-1.2
Pavlov. Cond. change in total contacts3.75.27.72.6-0.51.42.7-2.22.8-2.2-2.7
Pavlov. Cond. index score2.02.63.61.7-0.10.71.9-1.91.9-1.9-1.8
Pavlov. Cond. latency score1.72.13.21.5-0.20.61.8-1.61.8-1.6-1.7
Pavlov. Cond. lever contacts1.52.13.41.8-0.60.71.8-1.31.8-1.3-1.8
Pavlov. Cond. magazine entry number1.41.83.8-1.0-0.8-0.3-1.32.0-1.42.01.2
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.00.50.4-0.3-0.0-0.4-0.00.3
Pavlov. Cond. lever-magazine prob. diff.2.12.83.91.7-0.10.81.9-1.92.0-1.9-1.9
Pavlov. Cond. response bias1.62.23.31.7-0.20.81.7-1.61.8-1.6-1.7
Conditioned reinforcement - actives0.20.10.30.40.6-0.5-0.2-0.5-0.0-0.5-0.1
Conditioned reinforcement - inactives0.40.41.3-0.60.5-0.5-1.10.4-0.70.40.7
Conditioned locomotion1.01.21.9-1.20.5-1.2-1.20.9-1.30.91.4
Intermittent access intake day 1-15 change1.01.02.9-0.41.71.0-0.6-1.2-0.6-1.20.4
Intermittent access intake escalation1.11.03.6-0.51.90.7-0.7-1.1-0.7-1.10.6
Intermittent access intake escalation 21.21.22.0-1.40.9-0.3-1.40.6-1.40.61.4
Intermitt. access day 1 inactive lever presses0.91.01.60.90.60.70.7-1.21.1-1.2-1.1
Intermitt. access day 15 inactive lever presses0.40.41.70.40.9-1.3-0.70.1-0.20.10.2
Intermitt. access escalation Index0.10.10.3-0.30.6-0.3-0.1-0.1-0.2-0.10.2
Intermittent access day 1 total infusions1.11.32.8-1.0-1.2-0.8-0.81.7-0.51.70.8
Intermittent access day 15 total infusions0.91.02.1-1.40.90.0-1.40.4-1.10.41.2
Intermittent access terminal intake (last 3 days)1.01.11.6-1.2-0.3-0.6-1.31.2-0.91.21.2
Intermittent access total infusions0.50.61.2-1.1-0.20.2-1.00.8-0.60.80.8
Intermittent access day 1 locomotion0.10.10.2-0.5-0.30.1-0.30.40.00.40.2
Intermittent access day 15 total locomotion0.20.20.4-0.60.50.0-0.6-0.0-0.4-0.00.6
Intermittent access total locomotion0.20.20.5-0.7-0.3-0.4-0.40.4-0.10.40.3
Intermittent access standard deviation1.11.12.4-1.20.80.6-1.50.7-1.30.71.4
Cocaine induced anxiety1.82.14.8-0.71.0-2.2-2.01.1-1.51.11.3
Post-drug Anxiety0.00.10.2-0.10.1-0.4-0.30.2-0.20.2-0.1
Baseline Anxiety0.70.72.7-0.7-1.11.70.90.20.40.2-0.3
Lifetime Intake0.60.71.4-1.2-0.20.2-1.00.9-0.70.90.9
Incentive Sensitization - Responses0.60.61.40.00.5-0.9-1.20.8-0.70.80.6
Incentive Sensitization - Breakpoint0.50.51.30.20.6-0.8-1.20.6-0.70.60.5
Progressive ratio test 1 active lever presses0.30.30.5-0.3-0.4-0.3-0.70.7-0.50.70.4
Progressive ratio test 1 breakpoint0.20.20.5-0.2-0.7-0.2-0.50.7-0.30.70.3
Progressive ratio test 1 inactive lever presses0.10.10.40.1-0.50.6-0.30.30.20.3-0.1
Progressive ratio test 2 active lever presses0.80.82.0-0.50.2-0.7-1.41.1-0.91.10.9
Progressive ratio test 2 breakpoint0.40.41.2-0.20.1-0.6-1.10.8-0.50.80.5
Progressive ratio test 2 inactive lever presses1.72.04.1-1.10.4-0.9-2.01.5-1.51.51.6
Total sessions with >9 infusions0.50.61.10.3-1.00.21.0-0.70.8-0.7-0.9
Short access day 1 total inactive lever presses0.20.20.6-0.0-0.70.30.30.50.50.5-0.2
Short access day 10 total inactive lever presses0.40.41.9-0.21.4-0.9-0.7-0.2-0.3-0.20.4
Short access day 1 total infusions0.30.31.3-0.1-1.2-0.20.20.50.40.5-0.2
Short access day 10 total infusions0.20.20.9-0.2-1.00.70.30.20.30.2-0.2
Short access total infusions0.20.20.6-0.5-0.80.3-0.30.6-0.00.60.3
Short access day 1 locomotion0.40.41.00.6-1.0-0.50.6-0.10.7-0.1-0.7
Short access day 10 total locomotion1.11.23.10.6-1.8-0.21.40.21.50.2-1.2
Short access total locomotion1.31.32.80.7-1.40.61.5-0.61.7-0.6-1.4
Compulsive drug intake0.40.41.00.5-0.4-0.31.0-0.40.8-0.4-0.7
One hour access (0.3 mA shock)0.10.10.5-0.60.0-0.7-0.2-0.0-0.3-0.00.3
One hour access (shock baseline)0.10.20.5-0.70.1-0.2-0.50.1-0.40.10.5
Number of responses in last shaping day2.02.03.61.9-1.40.21.7-0.61.8-0.6-1.9
Context. condit. distance diff. score0.50.72.61.30.7-1.6-0.5-0.2-0.4-0.2-0.1
Locomotion velocity, session 10.40.41.4-0.3-0.61.20.7-0.10.6-0.1-0.5
Locomotion distance, session 10.91.23.9-0.72.00.3-1.2-0.5-1.3-0.51.0
Locomotion velocity, session 20.30.41.0-0.60.50.0-1.00.3-0.80.30.8
Locomotion distance, session 21.01.42.6-1.61.10.3-1.50.6-1.50.61.5
Locomotion velocity, session 32.32.74.4-1.9-1.2-1.5-1.22.1-1.32.11.5
Locomotion distance, session 31.71.83.2-1.8-1.2-0.7-0.91.8-1.11.81.3
Stereotopy head waving bouts, day 31.31.52.71.6-1.5-0.71.40.01.60.0-1.6
Stereotopy head waving duration, day 30.40.51.00.7-1.0-0.80.50.50.70.5-0.7
Locomotion velocity, session 71.11.22.8-0.6-0.1-1.7-1.31.1-1.21.11.1
Locomotion distance, session 70.30.41.1-0.01.1-0.1-0.6-0.8-0.5-0.80.3
Stereotopy head waving bouts, day 71.11.33.91.2-2.0-1.30.70.80.80.8-0.9
Stereotopy head waving duration, day 71.21.54.11.1-2.0-1.70.90.71.00.7-1.0
Locomotion velocity, session 80.70.92.21.50.6-0.40.6-1.20.5-1.2-0.9
Locomotion distance, session 80.71.12.20.11.1-1.4-1.50.4-1.50.41.0
Degree of sensitization distance1.51.63.51.31.60.60.3-1.90.6-1.9-0.8
Degree of sensitization stereotypy0.80.82.60.9-1.6-1.20.30.80.40.8-0.5
Condit. Reinf. active minus inactive responses0.40.40.80.80.1-0.90.8-0.60.5-0.6-0.5
Condit. Reinf. active-inactive response ratio0.10.10.20.0-0.4-0.50.50.00.30.0-0.1
Condit. Reinf. active responses0.20.30.50.40.7-0.50.3-0.70.1-0.7-0.1
Condit. Reinf. inactive responses0.91.03.30.61.80.6-0.1-1.4-0.1-1.4-0.1
Incentive salience index mean0.20.20.90.40.3-0.90.4-0.40.2-0.4-0.2
Condit. Reinf. lever presses0.10.10.30.20.0-0.10.5-0.20.3-0.2-0.3
Time in familiar zone, hab. session 10.40.31.9-0.7-0.31.40.3-0.20.4-0.2-0.0
Time in novel zone, hab. session 10.40.42.60.5-0.1-1.6-0.10.4-0.10.4-0.0
Total zone transitions, hab. session 10.50.71.3-0.30.4-1.1-1.00.8-1.10.80.8
Total locomotion distance, hab. session 11.92.85.3-1.01.2-1.4-2.31.4-2.31.41.9
Locomotion velocity, hab. session 11.72.44.9-0.91.3-1.1-2.21.2-2.21.21.8
Time in familiar zone, hab. session 22.02.13.31.5-0.60.81.8-1.31.8-1.3-1.8
Time in novel zone, hab. session 21.61.62.9-0.91.2-1.0-1.70.8-1.70.81.6
Total zone transitions, hab. session 20.30.41.21.10.9-0.40.0-0.70.1-0.7-0.4
Total locomotion distance, hab. session 20.50.73.10.51.8-0.4-0.9-0.2-0.9-0.20.5
Locomotion velocity, hab. session 20.50.62.20.21.5-0.6-1.00.0-1.00.00.6
Novel to familiar place preference ratio3.23.44.8-1.8-0.6-1.9-2.02.2-1.82.21.8
Novelty place preference3.13.25.3-1.6-1.1-1.9-1.72.3-1.52.31.6
Time in novel zone, NPP test2.42.53.9-1.4-0.8-1.8-1.62.0-1.42.01.4
Total zone transitions, NPP test0.60.82.71.60.90.00.4-1.10.3-1.1-0.8
Total locomotion distance, NPP test0.40.52.11.10.8-1.4-0.40.0-0.40.0-0.1
Locomotion velocity, NPP test0.50.83.30.50.4-1.8-0.80.7-0.80.70.4
Pavlov. Cond. lever latency1.41.72.6-1.30.0-1.4-1.61.3-1.41.31.4
Pavlov. Cond. magazine entry latency2.33.05.92.1-1.10.32.4-1.02.2-1.0-2.3
Pavlov. Cond. change in total contacts4.75.09.02.8-1.20.73.0-1.62.7-1.6-2.9
Pavlov. Cond. index score2.22.95.61.9-0.80.72.4-1.32.2-1.3-2.2
Pavlov. Cond. latency score1.72.24.41.5-0.80.82.1-1.01.9-1.0-1.9
Pavlov. Cond. lever contacts2.73.25.21.8-0.41.62.3-1.72.1-1.7-2.1
Pavlov. Cond. magazine entry number3.94.98.0-2.70.4-0.6-2.82.0-2.72.02.8
Pavlov. Cond. intertrial magazine entries0.40.52.00.21.4-0.1-0.9-0.6-0.7-0.60.5
Pavlov. Cond. lever-magazine prob. diff.2.32.95.61.8-0.80.72.4-1.42.2-1.4-2.2
Pavlov. Cond. response bias4.35.38.42.8-0.40.82.9-2.22.7-2.2-2.9
Bone: apparent density1.01.63.11.0-0.91.11.7-0.91.7-0.9-1.5
Bone surface1.32.24.01.3-1.21.72.0-0.71.9-0.7-1.8
Bone volume1.32.24.31.1-1.90.82.1-0.32.0-0.3-1.8
Bone: connectivity density0.10.20.50.40.00.20.7-0.40.6-0.4-0.5
Bone: cortical apparent density0.70.95.7-1.20.52.40.2-0.30.0-0.30.3
Bone: cortical area1.11.63.5-1.4-1.9-0.3-0.21.9-0.41.90.7
Bone: cortical porosity0.40.40.60.80.3-0.80.5-0.60.6-0.6-0.6
Bone: cortical porosity0.40.40.70.80.0-0.50.7-0.60.8-0.6-0.8
Bone: cortical thickness1.72.85.0-2.20.3-1.1-1.81.5-2.01.52.1
Bone: cortical thickness4.95.710.4-2.62.1-0.7-3.21.4-3.21.43.1
Bone: cortical tissue density0.71.05.9-1.10.52.40.2-0.40.1-0.40.2
Bone: elastic displacement0.80.92.0-1.41.1-0.2-1.30.0-1.10.01.2
Bone: elastic work0.50.71.6-0.51.3-1.0-1.0-0.3-0.9-0.30.8
Bone: endosteal estimation1.43.011.20.9-3.40.81.81.11.81.1-1.5
Bone: endosteal perimeter1.12.49.40.4-3.10.61.41.41.31.4-1.0
Bone: final force0.50.73.50.3-0.7-1.9-0.30.9-0.30.90.2
Bone: final moment0.20.41.80.7-0.6-1.30.10.50.10.5-0.2
Bone: marrow area1.53.311.61.0-3.40.91.91.02.01.0-1.7
Bone: maximum diameter1.12.17.6-0.5-2.80.90.61.90.41.9-0.1
Bone: maximum force1.62.85.5-0.6-2.3-2.3-0.52.3-0.62.30.7
Bone: maximum moment1.11.94.7-0.3-2.2-1.8-0.11.9-0.21.90.3
Bone: minimum diameter1.63.012.6-0.4-3.50.61.61.51.71.5-1.0
Bone: periosteal estimation1.12.39.60.0-3.10.51.01.71.01.7-0.7
Bone: periosteal perimeter1.42.49.30.5-3.10.61.61.31.41.3-1.1
Bone: post-yield work1.52.04.9-0.5-2.1-0.8-0.52.2-0.72.20.7
Bone: stiffness1.93.06.3-1.0-2.5-1.6-0.42.5-0.72.50.9
Bone: tissue strength1.51.43.71.11.40.40.4-1.90.4-1.9-0.7
Bone: trabecular number0.30.52.1-0.3-0.41.40.9-0.30.8-0.3-0.4
Bone: trabecular spacing1.51.94.6-1.5-0.1-2.1-1.31.1-1.31.11.4
Bone: trabecular thickness1.11.42.61.3-1.10.61.6-0.51.5-0.5-1.5
Bone: trabecular tissue density1.82.55.30.5-1.91.42.3-0.82.1-0.8-1.8
Breakpoint value in progressive ratio session1.92.13.81.9-1.6-1.21.8-0.51.5-0.5-1.8
Distance traveled before self-admin0.10.10.4-0.20.6-0.2-0.3-0.3-0.3-0.30.1
Distance traveled after self-admin0.30.31.30.3-1.1-0.50.40.30.30.3-0.4
Delta time in closed arm before/after self-admin0.10.10.3-0.30.20.6-0.30.40.00.40.3
Delta time in open arm before/after self-admin3.33.24.72.20.80.61.8-2.11.8-2.1-2.1
Diff in mean of infusions in LGA sessions2.32.66.42.50.41.21.5-1.51.6-1.5-1.9
Extinction: sum of active levers before priming1.91.96.90.7-2.6-1.41.50.31.30.3-1.3
Active lever presses in extinction session 63.83.76.42.5-1.50.32.5-1.22.3-1.2-2.5
Delta distance traveled before/after self-admin1.31.42.31.3-1.20.71.4-0.71.5-0.7-1.4
Delta ambulatory time before/after self-admin1.21.21.91.4-1.20.71.3-0.61.4-0.6-1.3
Time in closed arm before self-admin0.30.40.80.80.3-0.50.4-0.60.6-0.6-0.9
Time in closed arm after self-admin0.10.10.2-0.10.20.1-0.30.50.00.50.2
Time in open arm before self-admin2.52.75.2-1.5-0.5-0.8-1.62.3-1.52.31.8
Time in open arm after self-admin1.71.93.41.7-0.70.81.7-0.91.8-0.9-1.8
Sum of active levers in priming session hrs 5-62.92.86.01.4-2.4-1.72.1-0.31.9-0.3-1.9
Time to tail flick, vehicle, before self-admin1.41.42.3-1.30.80.9-1.41.2-1.31.21.5
Time to tail flick, vehicle, after self-admin1.01.13.21.41.8-0.0-0.9-1.0-0.8-1.00.2
Time to tail flick, test, before self-admin1.91.93.7-1.11.0-1.5-1.90.9-1.60.91.6
Time to tail flick, test, after self-admin3.03.15.5-1.61.60.3-2.31.3-2.31.32.3
Delta time to tail flick, vehicle, before/after SA1.91.84.11.81.5-0.40.1-2.00.1-2.0-0.9
Delta time to tail flick, test, before/after SA0.70.71.0-0.80.40.7-1.00.7-1.00.71.0
Ambulatory time before self-admin0.20.20.40.00.50.00.2-0.70.1-0.7-0.2
Ambulatory time after self-admin0.80.91.81.3-1.0-0.51.0-0.60.9-0.6-1.1
Total heroin consumption2.42.85.82.0-2.4-1.71.70.31.70.3-2.0
Area under the delay curve0.50.50.90.6-0.00.30.8-0.80.9-0.8-1.0
Delay disc. indifference point, 0s delay1.82.03.81.31.71.50.7-1.90.6-1.9-1.0
Delay disc. indifference point, 16s delay0.30.31.2-0.2-1.10.10.00.80.30.8-0.2
Delay disc. indifference point, 2s delay0.91.01.81.30.8-0.10.7-1.30.8-1.3-1.0
Delay disc. indifference point, 24s delay0.10.10.2-0.3-0.00.3-0.40.4-0.30.40.3
Delay disc. indifference point, 4s delay0.10.10.8-0.9-0.20.40.10.20.10.20.2
Delay disc. indifference point, 8s delay1.92.03.31.5-0.10.41.6-1.51.7-1.5-1.8
Delay discount exponential model param0.40.40.7-0.50.1-0.2-0.70.6-0.80.60.8
Delay discount hyperbolic model param0.30.30.6-0.4-0.0-0.1-0.60.6-0.80.60.7
Fecal boli incidents, locomotor time 10.50.51.60.00.7-1.3-1.00.1-0.90.10.6
Change in fecal boli incidents, locomotor task2.72.64.9-1.9-1.00.0-1.32.2-1.42.21.6
Time >=10cm from walls, locomotor time 10.70.73.80.7-0.1-1.9-0.30.5-0.50.50.2
Bouts of movement, locomotor time 11.51.73.80.6-1.81.02.0-0.51.7-0.5-1.5
Total resting periods, locomotor time 11.11.22.80.4-1.61.01.7-0.31.4-0.3-1.2
Rest time, locomotor task time 10.10.20.4-0.6-0.50.60.10.4-0.20.40.2
Distance moved, locomotor task time 10.10.10.30.10.5-0.4-0.2-0.20.0-0.20.2
Vertical activity count, locomotor time 10.80.92.2-0.41.3-0.9-1.50.2-1.00.21.0
Time >=10cm from walls, locomotor time 21.51.64.1-0.21.7-2.0-1.40.2-1.50.21.2
Bouts of movement, locomotor time 21.81.95.10.3-0.42.21.4-1.31.6-1.3-1.5
Total resting periods, locomotor time 21.81.96.30.1-0.42.51.3-1.21.5-1.2-1.4
Rest time, locomotor task time 21.01.22.0-1.41.21.3-1.30.2-1.10.21.2
Distance moved, locomotor task time 20.60.71.71.3-0.1-0.70.9-0.71.0-0.7-0.9
Vertical activity count, locomotor time 20.10.10.50.30.5-0.7-0.2-0.3-0.1-0.3-0.0
Weight adjusted by age2.32.54.42.0-1.7-0.21.9-0.62.1-0.6-2.1
Seeking ratio, delayed vs. immediate footshock0.50.61.1-0.80.60.2-1.00.6-0.90.61.0
Locomotion in novel chamber0.70.82.2-1.50.10.1-0.90.8-1.00.81.1
Locomotion in novel chamber post-restriction0.40.51.9-0.4-0.7-1.40.10.8-0.10.80.2
Progressive ratio0.10.20.50.7-0.6-0.20.20.40.20.4-0.2
Food seeking constrained by brief footshock0.20.20.50.70.7-0.1-0.1-0.5-0.1-0.5-0.2
Seeking ratio, punishment vs. effort0.10.10.40.00.6-0.2-0.1-0.6-0.0-0.6-0.1
Run reversals in cocaine runway, females0.80.81.60.5-0.60.71.3-0.91.1-0.9-1.0
Run reversals in cocaine runway, males0.70.62.20.20.51.50.7-0.80.7-0.8-0.4
Latency to leave start box in cocaine runway1.82.05.31.00.52.31.1-1.61.2-1.6-1.2
Latency to leave start box in cocaine runway, F0.91.02.40.8-0.11.61.1-0.91.1-0.9-1.0
Latency to leave start box in cocaine runway, M0.50.52.20.40.31.50.4-0.70.6-0.7-0.5
Cd content in liver1.01.12.7-0.41.6-0.6-1.4-0.0-1.4-0.01.2
Co content in liver0.30.41.10.7-1.1-0.20.40.60.40.6-0.3
Cu content in liver1.11.33.21.11.60.30.2-1.80.2-1.8-0.5
Fe content in liver0.50.62.10.2-0.81.40.9-0.21.0-0.2-0.7
K content in liver0.10.10.4-0.6-0.50.50.4-0.10.4-0.1-0.0
Mg content in liver1.11.13.4-0.20.01.81.1-1.21.1-1.2-0.7
Mn content in liver0.50.61.3-1.1-0.90.9-0.00.7-0.10.70.6
Na content in liver0.50.50.80.50.10.60.9-0.80.8-0.8-0.8
Rb content in liver0.50.64.20.10.52.0-0.1-0.40.1-0.40.1
Se content in liver0.20.30.90.10.90.3-0.7-0.1-0.7-0.10.5
Sr content in liver0.70.61.2-0.40.1-1.1-1.10.5-1.10.51.0
Zn content in liver1.11.32.70.10.81.01.1-1.61.1-1.6-0.8