Cacnb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000054274 0.12 0.08 5.8e-07 0.12 0.12 0.11 0.11 9.5e-07 5.1e-07 1.2e-06 1.5e-06
2 BLA isoform ratio ENSRNOT00000081206 0.07 0.07 3.9e-03 0.05 -0 0.04 0.01 1.1e-03 6.1e-01 3.6e-03 7.6e-02
3 BLA isoform ratio ENSRNOT00000097309 0.08 0.08 1.3e-03 0.06 0 0.05 0.02 4.6e-04 2.3e-01 1.2e-03 3.8e-02
4 Brain alternative TSS ENSRNOT00000081206 0.06 0.08 8.0e-03 0.02 0.01 0 0.01 6.7e-03 2.6e-02 2.1e-01 4.7e-02
5 Brain alternative TSS ENSRNOT00000097309 0.04 0.05 9.3e-03 0.02 0.02 0.01 0.01 4.7e-03 1.2e-02 3.6e-02 1.9e-02
6 Brain alternative TSS ENSRNOT00000081206 0.06 0.08 9.0e-03 0.02 0.01 -0 0.01 7.7e-03 3.0e-02 4.4e-01 5.5e-02
7 Brain alternative TSS ENSRNOT00000097309 0.04 0.05 9.6e-03 0.02 0.01 0 0.01 5.0e-03 1.3e-02 1.1e-01 2.0e-02
8 Brain gene expression ENSRNOG00000054274 0.24 0.1 0.0e+00 0.38 0.36 0.36 0.36 7.4e-37 3.8e-35 1.1e-34 6.5e-35
9 Brain isoform ratio ENSRNOT00000097309 0.05 0.07 4.2e-03 0.02 0.02 0.01 0.01 2.4e-03 7.2e-03 6.7e-02 1.5e-02
10 Brain intron excision ratio chr7:129785003:129791917 0.06 0.05 3.0e-03 0.02 0.02 0.03 0.03 1.2e-02 8.5e-03 7.8e-04 7.4e-04
11 Brain intron excision ratio chr7:129787673:129791917 0.05 0.05 4.8e-03 0.02 0.01 0.03 0.03 1.1e-02 1.3e-02 1.2e-03 1.2e-03
12 Eye gene expression ENSRNOG00000054274 0.33 0.17 1.1e-04 0.2 0.27 0.29 0.24 5.1e-04 5.0e-05 2.2e-05 1.4e-04
13 Eye isoform ratio ENSRNOT00000095350 0.76 0.18 2.9e-03 0.13 0.24 0.09 0.22 5.8e-03 1.5e-04 1.5e-02 2.4e-04
14 IL gene expression ENSRNOG00000054274 0.16 0.1 4.0e-04 0.16 0.16 0.12 0.15 1.3e-04 1.1e-04 8.9e-04 2.3e-04
15 Liver gene expression ENSRNOG00000054274 0.02 0.02 7.5e-03 -0 0.01 -0 0 4.2e-01 6.4e-02 3.9e-01 1.7e-01
16 NAcc gene expression ENSRNOG00000054274 0.04 0.03 4.9e-03 0.03 0.03 0.01 0.03 1.9e-03 3.4e-03 2.7e-02 3.0e-03
17 OFC alternative TSS ENSRNOT00000081206 0.94 0.04 1.5e-05 0.1 0.14 0.14 0.12 2.3e-03 3.6e-04 4.2e-04 7.0e-04
18 OFC alternative TSS ENSRNOT00000081206 0.94 0.04 1.5e-05 0.09 0.15 0.14 0.12 3.6e-03 2.4e-04 4.1e-04 6.9e-04
19 OFC gene expression ENSRNOG00000054274 0.32 0.14 1.7e-07 0.23 0.21 0.16 0.22 3.1e-06 1.0e-05 1.0e-04 5.5e-06
20 OFC isoform ratio ENSRNOT00000081206 0.74 0.18 1.2e-03 0.05 0.06 0.08 0.08 2.2e-02 1.6e-02 5.3e-03 5.8e-03
21 PL gene expression ENSRNOG00000054274 0.11 0.06 5.9e-12 0.15 0.16 0.16 0.16 1.2e-11 3.0e-12 5.3e-12 4.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
BMI with tail3.712.117.23.8-3.93.9-4.04.0-4.04.03.84.04.0-3.82.5-1.13.8-4.13.8-0.7-0.63.3-2.43.9
BMI without tail0.10.21.10.1-0.80.8-0.20.2-0.20.20.00.20.4-0.40.1-1.00.3-0.2-0.00.60.60.50.50.2
Body weight5.322.432.05.2-5.75.7-5.45.4-5.45.45.05.44.7-4.33.2-0.35.3-5.35.0-2.1-1.94.9-3.85.3
Epididymis fat weight0.20.51.40.6-1.21.2-0.60.6-0.60.60.40.60.8-0.80.6-0.60.6-0.80.4-0.7-0.70.4-0.40.6
Glucose0.10.20.70.4-0.90.9-0.50.5-0.50.50.40.50.10.00.10.20.5-0.20.3-0.3-0.30.8-0.20.4
Heart weight0.10.20.60.10.5-0.5-0.30.3-0.30.30.30.30.7-0.70.2-0.70.0-0.40.30.70.7-0.30.30.1
Left kidney weight0.61.76.40.8-0.40.4-1.11.1-1.11.11.11.12.4-2.50.9-2.30.8-1.61.11.21.30.10.50.9
Right kidney weight2.26.38.52.8-2.92.9-2.92.9-2.92.92.92.92.3-2.01.80.32.8-2.82.8-1.4-1.32.6-2.22.8
Tail length0.10.20.5-0.4-0.20.20.4-0.40.4-0.4-0.5-0.4-0.70.7-0.30.2-0.30.6-0.50.00.0-0.00.3-0.4
Length with tail1.65.98.72.7-3.03.0-2.82.8-2.82.82.62.82.1-1.81.60.52.7-2.62.6-1.5-1.42.5-2.22.7
Length without tail6.013.218.84.0-3.63.6-4.34.3-4.34.34.04.34.1-3.92.5-0.64.0-4.34.1-1.2-1.13.2-2.84.1
Liver weight, left1.62.63.51.8-1.91.9-1.81.8-1.81.81.81.81.6-1.41.1-0.01.8-1.81.7-1.0-1.01.6-1.21.8
Liver weight, right1.42.34.11.6-2.02.0-1.61.6-1.61.61.61.61.3-1.11.00.11.7-1.61.6-1.4-1.41.7-1.21.7
Parametrial fat weight1.63.24.7-2.11.7-1.71.9-1.91.9-1.9-2.0-1.9-1.00.8-1.1-1.4-2.01.7-2.11.51.5-2.02.2-2.0
Retroperitoneal fat weight0.51.76.4-1.21.1-1.10.8-0.80.8-0.8-1.2-0.80.4-0.6-0.6-2.5-1.10.6-1.12.02.0-1.42.2-1.1
Intraocular pressure6.18.712.1-3.23.2-3.23.3-3.33.3-3.3-3.3-3.3-3.02.8-2.10.1-3.23.4-3.51.71.6-2.92.4-3.3
Extensor digitorum longus weight3.714.924.44.2-4.94.9-4.54.5-4.54.53.84.53.1-2.72.30.64.5-3.94.1-2.0-1.94.3-3.24.3
Soleus weight0.51.62.91.4-1.71.7-1.31.3-1.31.31.31.30.5-0.30.70.91.4-1.11.4-1.3-1.31.5-1.41.4
Tibialis anterior weight1.14.09.42.1-3.13.1-2.32.3-2.32.31.72.31.0-0.60.80.82.4-1.61.8-1.1-1.12.6-1.52.1
Tibia length6.117.223.74.7-4.94.9-4.84.8-4.84.84.54.83.5-3.12.81.04.7-4.54.6-1.9-1.84.4-4.04.7
Number of licking bursts0.30.42.0-0.30.1-0.10.3-0.30.3-0.3-0.5-0.3-1.31.4-0.61.2-0.20.9-0.6-0.1-0.20.30.1-0.4
Food consumed during 24 hour testing period1.51.83.91.3-1.01.0-1.51.5-1.51.51.71.52.0-2.01.0-1.11.2-1.81.70.60.60.6-0.51.4
Times rat made contact with spout0.30.42.2-0.30.2-0.20.0-0.00.0-0.0-0.1-0.00.6-0.7-0.1-1.5-0.2-0.1-0.11.31.3-0.41.0-0.2
Mean time between licks in bursts0.20.20.4-0.40.6-0.60.5-0.50.5-0.5-0.6-0.5-0.50.4-0.20.4-0.50.4-0.6-0.3-0.3-0.50.0-0.4
Mean num. licks in bursts0.60.85.1-0.20.5-0.50.2-0.20.2-0.20.0-0.21.4-1.60.4-2.2-0.4-0.60.21.21.2-1.01.0-0.1
Std. dev. time between licks in bursts0.70.91.6-1.00.8-0.81.0-1.01.0-1.0-1.1-1.0-1.21.2-0.70.4-0.91.2-1.20.40.3-0.70.6-1.0
Water consumed over 24 hours0.00.00.10.0-0.10.1-0.00.0-0.00.00.20.00.2-0.20.2-0.4-0.0-0.20.2-0.0-0.0-0.20.00.0
Indifference point 0 sec1.62.63.6-1.91.2-1.21.8-1.81.8-1.8-1.7-1.8-1.61.5-1.2-0.5-1.81.8-1.91.41.3-1.71.6-1.9
Indifference point AUC0.20.20.7-0.40.3-0.30.5-0.50.5-0.5-0.2-0.5-0.80.8-0.40.7-0.40.7-0.20.50.5-0.30.0-0.5
Indifference point function ln k2.94.15.22.3-2.22.2-2.32.3-2.32.32.22.31.6-1.41.40.62.2-2.22.2-1.7-1.62.1-2.02.3
Indifference point function log k2.94.15.22.3-2.22.2-2.32.3-2.32.32.22.31.6-1.41.40.62.2-2.22.2-1.7-1.62.1-2.02.3
Delay discounting total patch changes 0 sec1.52.43.5-1.81.1-1.11.8-1.81.8-1.8-1.7-1.8-1.81.7-1.2-0.2-1.81.9-1.81.21.1-1.51.5-1.8
Delay discounting total patch changes 12 sec1.41.83.0-1.51.0-1.01.5-1.51.5-1.5-1.4-1.5-1.71.6-1.10.2-1.41.7-1.51.21.2-1.21.2-1.5
Delay discounting total patch changes 18 sec3.04.07.7-2.21.3-1.32.3-2.32.3-2.3-2.1-2.3-2.82.7-1.50.8-2.22.6-2.20.60.5-1.61.3-2.3
Delay discounting total patch changes 24 sec1.41.85.0-1.40.6-0.61.4-1.41.4-1.4-1.4-1.4-2.22.2-1.11.1-1.31.9-1.30.10.0-0.80.7-1.4
Delay discounting total patch changes 6 sec1.92.83.7-1.91.5-1.51.8-1.81.8-1.8-1.7-1.8-1.61.5-1.2-0.3-1.91.9-1.81.71.6-1.81.7-1.9
Delay discounting time to switch 0 sec2.03.04.9-1.92.0-2.01.8-1.81.8-1.8-2.2-1.8-1.71.6-1.20.1-1.92.0-2.20.90.8-1.91.5-1.9
Delay discounting water rate 0 sec2.74.46.82.3-2.62.6-2.32.3-2.32.32.42.31.6-1.41.30.42.4-2.22.5-1.2-1.22.5-1.92.3
Delay discounting water rate 12 sec3.24.86.52.4-2.32.3-2.42.4-2.42.42.42.41.6-1.41.50.92.4-2.32.4-2.1-2.02.5-2.32.4
Delay discounting water rate 18 sec0.30.40.90.6-0.90.9-0.70.7-0.70.70.60.70.4-0.40.4-0.00.7-0.60.5-0.7-0.70.8-0.40.7
Delay discounting water rate 24 sec2.73.85.22.2-2.12.1-2.12.1-2.12.12.22.10.9-0.61.21.62.2-1.82.1-1.8-1.72.3-2.22.1
Delay discounting water rate 6 sec3.24.66.32.4-2.32.3-2.32.3-2.32.32.52.31.6-1.41.40.72.4-2.32.4-1.8-1.82.5-2.12.4
Locomotor activity0.71.21.9-1.21.1-1.11.2-1.21.2-1.2-1.2-1.2-1.41.4-0.90.2-1.11.4-1.20.40.3-0.91.1-1.2
Locomotor testing distance2.23.65.2-2.12.0-2.02.1-2.12.1-2.1-2.1-2.1-2.12.0-1.40.1-2.02.3-2.10.80.7-1.71.8-2.1
Locomotor testing rearing1.82.85.0-1.81.6-1.61.8-1.81.8-1.8-2.0-1.8-2.22.2-1.30.9-1.72.2-2.00.50.4-1.31.2-1.8
Light reinforcement 12.34.210.2-2.11.3-1.32.3-2.32.3-2.3-2.2-2.3-3.23.2-1.61.5-2.02.7-2.1-0.4-0.5-1.31.0-2.2
Light reinforcement 20.70.91.4-1.10.9-0.91.2-1.21.2-1.2-1.1-1.2-0.90.8-0.6-0.2-1.01.1-1.10.00.0-0.80.8-1.0
Reaction time number correct0.91.22.61.3-0.20.2-1.11.1-1.11.11.61.10.7-0.60.91.01.1-1.21.5-1.1-1.11.0-1.61.3
Reaction time mean minus median7.49.714.7-3.53.5-3.53.3-3.33.3-3.3-3.2-3.3-1.51.2-1.9-2.2-3.52.9-3.43.23.1-3.73.8-3.4
Reaction time mean minus median AUC5.47.010.0-2.93.0-3.02.9-2.92.9-2.9-2.8-2.9-1.41.0-1.6-1.7-3.02.5-3.02.32.2-3.23.1-2.9
Reaction time num false alarms1.62.23.4-1.61.8-1.81.6-1.61.6-1.6-1.4-1.6-1.10.9-0.9-0.3-1.71.5-1.41.51.5-1.81.3-1.6
Reaction time num false alarms AUC2.43.45.3-2.02.3-2.32.0-2.02.0-2.0-1.8-2.0-1.00.8-1.0-0.9-2.11.7-1.92.02.0-2.31.8-2.0
Reaction time trials correct on left0.91.22.61.3-0.20.2-1.11.1-1.11.11.61.10.7-0.60.91.01.1-1.21.5-1.1-1.11.0-1.61.3
Reaction time trials on left0.70.92.11.1-0.00.0-1.01.0-1.01.01.41.00.6-0.50.80.91.0-1.11.3-1.0-0.90.8-1.51.1
Reaction time mean0.60.82.2-0.91.0-1.00.8-0.80.8-0.8-0.9-0.8-0.1-0.1-0.5-1.1-0.90.7-1.11.11.0-1.01.5-0.9
Reaction time mean AUC0.40.61.8-0.70.8-0.80.5-0.50.5-0.5-0.7-0.50.3-0.4-0.3-1.2-0.60.4-0.81.11.1-0.81.4-0.6
Median of all reaction times0.10.10.40.2-0.20.2-0.30.3-0.30.30.10.30.5-0.60.2-0.60.2-0.3-0.00.10.10.20.30.2
Reaction time omissions8.111.014.4-3.83.8-3.83.8-3.83.8-3.8-3.6-3.8-2.52.2-2.1-1.3-3.83.5-3.62.12.0-3.53.5-3.8
Reaction time false alarm rate2.33.24.5-2.01.7-1.71.9-1.91.9-1.9-2.0-1.9-1.00.8-1.1-1.1-2.01.7-2.02.02.0-2.12.0-2.0
Reaction time premature initiation rate4.56.19.3-2.82.4-2.42.6-2.62.6-2.6-2.9-2.6-2.62.5-1.9-0.0-2.63.0-2.81.81.7-2.22.6-2.8
Reaction time premature initiations2.43.45.1-2.02.2-2.21.9-1.91.9-1.9-1.9-1.9-2.12.1-1.40.5-1.92.3-1.91.21.1-1.61.6-2.0
Std. dev. reaction times5.47.411.2-3.03.2-3.22.9-2.92.9-2.9-2.9-2.9-1.41.0-1.7-1.9-3.02.6-3.12.52.5-3.23.3-3.0
Reaction time trials completed0.70.92.11.1-0.00.0-1.01.0-1.01.01.41.00.6-0.50.80.91.0-1.11.3-1.0-0.90.8-1.51.1
Reaction time trials AUC1.11.63.31.5-0.40.4-1.31.3-1.31.31.71.30.8-0.71.01.11.3-1.41.6-1.3-1.31.2-1.81.4
Social response proportion0.20.21.4-0.40.5-0.50.1-0.10.1-0.1-0.4-0.10.1-0.1-0.2-0.6-0.40.2-0.41.21.2-0.50.8-0.4
Social responses6.28.010.9-3.13.0-3.02.9-2.92.9-2.9-3.1-2.9-2.92.8-2.1-0.0-3.13.3-3.22.42.3-2.82.7-3.2
Social time0.40.52.2-0.20.5-0.50.0-0.00.0-0.0-0.1-0.00.8-0.90.1-1.5-0.3-0.3-0.21.51.5-0.90.9-0.2
Conditioned locomotion0.50.63.60.3-0.20.2-0.20.2-0.20.20.20.2-1.01.1-0.11.90.30.30.1-1.4-1.50.7-1.10.2
Cocaine response after cond. corrected0.70.85.6-0.30.2-0.20.1-0.10.1-0.1-0.2-0.11.5-1.70.3-2.4-0.3-0.5-0.11.31.4-0.71.2-0.1
Cocaine response after cond. not corrected1.21.34.0-1.01.1-1.10.9-0.90.9-0.9-1.0-0.90.6-0.8-0.2-2.0-1.10.3-0.81.81.9-1.41.6-0.9
Cocaine response before conditioning3.34.06.1-2.12.4-2.42.2-2.22.2-2.2-2.0-2.2-2.52.4-1.41.0-2.12.4-1.91.00.9-1.91.1-2.2
Saline control response0.10.10.20.3-0.30.3-0.30.3-0.30.30.30.30.1-0.00.20.30.2-0.30.30.10.1-0.0-0.40.3
Condit. Reinf. active minus inactive responses0.10.10.5-0.1-0.10.10.3-0.30.3-0.3-0.0-0.3-0.60.7-0.10.7-0.20.30.0-0.5-0.5-0.0-0.3-0.2
Condit. Reinf. active-inactive response ratio0.30.30.4-0.60.5-0.50.6-0.60.6-0.6-0.5-0.6-0.40.3-0.3-0.3-0.60.5-0.50.60.6-0.60.6-0.6
Condit. Reinf. active responses0.20.31.1-0.50.1-0.10.6-0.60.6-0.6-0.4-0.6-1.11.1-0.30.7-0.50.7-0.4-0.4-0.4-0.3-0.0-0.5
Condit. Reinf. inactive responses0.70.82.5-0.80.6-0.61.0-1.01.0-1.0-0.8-1.0-1.51.6-0.61.0-0.81.2-0.9-0.3-0.3-0.60.1-0.9
Condit. Reinf. lever presses0.00.00.1-0.0-0.20.20.1-0.10.1-0.10.0-0.1-0.20.2-0.00.2-0.10.1-0.1-0.2-0.2-0.2-0.1-0.1
Condit. Reinf. lever reinforcers received0.50.71.5-0.90.5-0.51.0-1.01.0-1.0-0.7-1.0-1.21.2-0.50.5-0.91.0-0.8-0.2-0.2-0.70.4-0.9
Pavlov. Cond. lever latency0.00.00.10.1-0.00.00.0-0.00.0-0.00.1-0.0-0.10.10.10.20.0-0.00.1-0.2-0.2-0.0-0.20.0
Pavlov. Cond. magazine entry latency0.80.91.71.1-1.01.0-1.01.0-1.01.01.21.00.7-0.60.70.41.0-1.01.3-0.4-0.30.9-1.11.1
Pavlov. Cond. change in total contacts1.41.92.91.4-1.51.5-1.71.7-1.71.71.51.71.7-1.60.9-0.71.5-1.61.50.40.51.2-0.61.5
Pavlov. Cond. index score0.40.50.80.8-0.90.9-0.90.9-0.90.90.90.90.7-0.60.50.00.8-0.80.9-0.1-0.10.7-0.60.8
Pavlov. Cond. latency score0.50.61.00.9-0.90.9-0.90.9-0.90.91.00.90.8-0.70.5-0.10.9-0.91.0-0.0-0.00.7-0.60.9
Pavlov. Cond. lever contacts0.10.10.3-0.40.3-0.30.3-0.30.3-0.3-0.4-0.3-0.10.0-0.2-0.4-0.30.3-0.40.50.5-0.30.5-0.3
Pavlov. Cond. magazine entry number1.92.33.2-1.71.7-1.71.7-1.71.7-1.7-1.7-1.7-1.00.9-0.9-0.8-1.71.5-1.81.11.0-1.71.6-1.7
Pavlov. Cond. intertrial magazine entries4.05.16.9-2.62.6-2.62.5-2.52.5-2.5-2.3-2.5-1.61.3-1.5-1.2-2.52.4-2.41.81.7-2.32.6-2.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.41.1-1.11.1-1.11.1-1.11.11.21.10.8-0.70.60.31.1-1.01.2-0.3-0.21.0-0.91.1
Pavlov. Cond. response bias0.00.00.1-0.00.0-0.0-0.00.0-0.00.0-0.00.00.0-0.0-0.0-0.1-0.00.0-0.10.20.2-0.10.1-0.0
Conditioned reinforcement - actives1.21.21.6-1.21.0-1.01.2-1.21.2-1.2-1.2-1.2-1.11.0-0.7-0.2-1.21.3-1.20.90.9-1.11.0-1.2
Conditioned reinforcement - inactives1.41.62.9-1.51.3-1.31.3-1.31.3-1.3-1.4-1.3-0.60.5-0.7-1.2-1.41.2-1.41.31.3-1.21.7-1.4
Conditioned locomotion0.30.41.5-0.60.2-0.20.6-0.60.6-0.6-0.5-0.6-1.21.2-0.40.8-0.50.9-0.6-0.2-0.3-0.20.1-0.6
Intermittent access intake day 1-15 change1.11.12.6-1.21.1-1.11.0-1.01.0-1.0-1.2-1.0-0.20.1-0.6-1.3-1.10.9-1.21.01.0-1.21.6-1.1
Intermittent access intake escalation0.90.92.4-1.01.0-1.00.8-0.80.8-0.8-1.0-0.80.1-0.2-0.4-1.4-1.00.6-1.01.11.0-1.11.5-1.0
Intermittent access intake escalation 21.21.23.0-1.31.2-1.21.0-1.01.0-1.0-1.3-1.0-0.20.0-0.6-1.4-1.20.9-1.31.11.1-1.31.7-1.2
Intermitt. access day 1 inactive lever presses3.03.37.9-1.71.5-1.52.0-2.02.0-2.0-1.9-2.0-2.82.8-1.41.8-1.82.3-1.9-0.3-0.4-1.30.4-1.8
Intermitt. access day 15 inactive lever presses1.01.11.9-1.10.7-0.71.2-1.21.2-1.2-1.4-1.2-1.41.4-0.70.5-1.11.3-1.3-0.2-0.2-0.70.6-1.2
Intermitt. access escalation Index0.20.20.5-0.40.4-0.40.4-0.40.4-0.4-0.6-0.4-0.70.7-0.50.5-0.40.6-0.7-0.2-0.2-0.30.2-0.4
Intermittent access day 1 total infusions1.01.11.6-1.21.3-1.31.1-1.11.1-1.1-1.0-1.1-0.70.5-0.6-0.6-1.21.0-1.11.21.1-1.21.2-1.2
Intermittent access day 15 total infusions1.92.13.5-1.71.5-1.51.5-1.51.5-1.5-1.7-1.5-0.90.8-0.9-1.0-1.61.5-1.71.31.2-1.51.9-1.7
Intermittent access terminal intake (last 3 days)2.02.23.3-1.81.5-1.51.7-1.71.7-1.7-1.7-1.7-1.10.9-0.9-0.9-1.71.6-1.71.00.9-1.51.8-1.7
Intermittent access total infusions1.92.13.1-1.71.5-1.51.5-1.51.5-1.5-1.7-1.5-1.00.9-0.9-0.8-1.61.6-1.71.21.2-1.51.8-1.7
Intermittent access day 1 locomotion1.01.02.9-0.90.6-0.61.0-1.01.0-1.0-1.0-1.0-1.71.7-0.71.2-0.81.3-1.0-0.6-0.6-0.30.1-0.9
Intermittent access day 15 total locomotion1.21.33.8-1.10.6-0.61.2-1.21.2-1.2-1.2-1.2-1.91.9-0.81.0-0.91.6-1.3-0.7-0.7-0.30.4-1.1
Intermittent access total locomotion2.73.18.1-1.71.1-1.11.9-1.91.9-1.9-1.9-1.9-2.82.8-1.31.5-1.62.4-1.9-0.6-0.7-0.90.7-1.8
Intermittent access standard deviation0.50.61.3-0.81.0-1.00.6-0.60.6-0.6-0.8-0.6-0.0-0.1-0.4-0.9-0.70.5-0.81.11.1-0.91.1-0.7
Cocaine induced anxiety1.01.11.51.2-1.21.2-1.21.2-1.21.21.11.20.5-0.40.60.81.2-1.01.1-0.9-0.91.2-1.21.2
Post-drug Anxiety3.94.35.82.4-2.22.2-2.42.4-2.42.42.32.41.5-1.31.41.02.3-2.22.3-1.2-1.12.3-2.32.4
Baseline Anxiety0.90.91.51.0-1.01.0-1.11.1-1.11.11.01.11.2-1.20.7-0.41.0-1.21.0-0.2-0.21.0-0.61.1
Lifetime Intake1.61.83.4-1.61.3-1.31.3-1.31.3-1.3-1.6-1.3-0.90.8-0.9-1.0-1.51.4-1.61.21.2-1.31.8-1.5
Incentive Sensitization - Responses0.10.10.20.2-0.50.5-0.20.2-0.20.20.10.2-0.00.10.20.10.3-0.10.1-0.3-0.30.4-0.30.2
Incentive Sensitization - Breakpoint0.00.00.10.1-0.30.3-0.00.0-0.00.0-0.10.0-0.20.20.10.20.10.1-0.1-0.3-0.40.2-0.20.1
Progressive ratio test 1 active lever presses3.03.14.8-2.01.5-1.52.0-2.02.0-2.0-2.1-2.0-2.01.9-1.3-0.0-1.92.2-2.10.50.4-1.51.7-2.0
Progressive ratio test 1 breakpoint2.72.84.4-1.91.4-1.41.9-1.91.9-1.9-2.0-1.9-1.91.8-1.2-0.0-1.82.1-2.00.40.4-1.41.6-1.9
Progressive ratio test 1 inactive lever presses2.62.84.5-1.91.4-1.41.9-1.91.9-1.9-2.0-1.9-1.91.8-1.20.1-1.82.1-2.00.40.3-1.31.4-1.9
Progressive ratio test 2 active lever presses1.61.73.1-1.50.9-0.91.4-1.41.4-1.4-1.8-1.4-1.71.7-0.90.4-1.31.7-1.8-0.1-0.2-0.91.0-1.5
Progressive ratio test 2 breakpoint2.12.34.1-1.71.1-1.11.7-1.71.7-1.7-2.0-1.7-2.01.9-1.10.5-1.52.0-2.0-0.0-0.1-1.11.1-1.7
Progressive ratio test 2 inactive lever presses2.02.33.6-1.71.5-1.51.7-1.71.7-1.7-1.9-1.7-1.81.7-1.00.4-1.71.9-1.90.50.4-1.41.1-1.7
Total sessions with >9 infusions0.40.41.6-0.80.3-0.30.6-0.60.6-0.6-0.8-0.6-0.30.2-0.3-0.9-0.60.7-0.80.60.6-0.41.3-0.7
Short access day 1 total inactive lever presses0.91.02.0-1.20.8-0.81.0-1.01.0-1.0-1.3-1.0-0.80.8-0.8-0.5-1.11.2-1.40.70.6-0.81.3-1.1
Short access day 10 total inactive lever presses0.70.72.9-0.50.4-0.40.7-0.70.7-0.7-0.8-0.7-1.51.6-0.61.7-0.51.0-0.7-0.7-0.7-0.3-0.5-0.6
Short access day 1 total infusions0.10.10.6-0.1-0.20.2-0.10.1-0.10.1-0.20.10.4-0.40.1-0.80.0-0.0-0.20.00.00.20.6-0.0
Short access day 10 total infusions0.70.82.4-0.90.9-0.90.6-0.60.6-0.6-0.8-0.6-0.1-0.0-0.5-1.3-0.80.7-0.91.21.2-0.81.6-0.9
Short access total infusions0.20.31.2-0.60.2-0.20.3-0.30.3-0.3-0.5-0.3-0.10.1-0.3-0.9-0.40.5-0.60.70.7-0.41.1-0.5
Short access day 1 locomotion0.20.20.8-0.2-0.40.40.2-0.20.2-0.2-0.3-0.2-0.60.6-0.20.40.00.4-0.3-0.9-0.90.30.0-0.1
Short access day 10 total locomotion0.91.04.8-0.2-0.20.20.5-0.50.5-0.5-0.4-0.5-1.92.0-0.52.2-0.21.0-0.4-1.5-1.60.5-0.8-0.3
Short access total locomotion0.60.62.3-0.5-0.10.10.5-0.50.5-0.5-0.6-0.5-1.41.5-0.51.2-0.31.0-0.7-1.1-1.10.1-0.1-0.5
Compulsive drug intake0.70.71.10.9-0.80.8-0.90.9-0.90.91.00.91.1-1.00.5-0.20.8-1.10.90.20.30.6-0.60.9
One hour access (0.3 mA shock)0.20.20.8-0.50.4-0.40.3-0.30.3-0.3-0.5-0.3-0.0-0.0-0.2-0.8-0.40.3-0.50.80.8-0.50.9-0.5
One hour access (shock baseline)0.10.10.4-0.30.0-0.00.1-0.10.1-0.1-0.4-0.1-0.0-0.0-0.1-0.6-0.20.2-0.30.10.1-0.10.7-0.3
Number of responses in last shaping day0.40.41.90.3-1.01.0-0.40.4-0.40.4-0.00.4-0.30.40.10.70.5-0.00.0-1.4-1.40.7-0.40.4
Context. condit. distance diff. score0.20.30.50.6-0.70.7-0.70.7-0.70.70.40.70.3-0.20.30.20.6-0.50.3-0.5-0.50.7-0.30.6
Locomotion velocity, session 10.91.01.7-1.01.1-1.11.1-1.11.1-1.1-1.1-1.1-1.31.3-0.70.6-1.01.3-1.2-0.0-0.1-0.70.5-1.1
Locomotion distance, session 12.83.65.8-2.12.4-2.42.0-2.02.0-2.0-2.2-2.0-0.70.4-1.0-1.4-2.11.6-2.21.41.4-2.32.2-2.0
Locomotion velocity, session 20.30.30.8-0.60.9-0.90.6-0.60.6-0.6-0.6-0.6-0.1-0.0-0.2-0.4-0.60.4-0.50.70.7-0.80.4-0.6
Locomotion distance, session 22.23.14.7-1.92.1-2.11.9-1.91.9-1.9-2.0-1.9-0.70.4-0.9-1.2-2.01.5-2.01.51.5-2.21.9-1.9
Locomotion velocity, session 33.23.74.9-2.22.1-2.12.2-2.22.2-2.2-2.2-2.2-1.10.9-1.2-1.2-2.21.9-2.21.51.5-2.22.2-2.2
Locomotion distance, session 34.24.56.0-2.42.3-2.32.4-2.42.4-2.4-2.4-2.4-1.51.3-1.3-0.9-2.52.2-2.41.21.2-2.42.2-2.4
Stereotopy head waving bouts, day 31.01.22.31.3-0.80.8-1.21.2-1.21.21.31.20.5-0.30.61.21.3-1.01.3-0.9-0.91.3-1.51.2
Stereotopy head waving duration, day 30.40.51.50.9-0.20.2-0.70.7-0.70.71.00.70.2-0.10.41.00.8-0.60.9-0.5-0.50.8-1.20.8
Locomotion velocity, session 70.20.20.5-0.4-0.10.10.3-0.30.3-0.3-0.6-0.3-0.50.6-0.20.1-0.30.5-0.6-0.7-0.7-0.10.3-0.4
Locomotion distance, session 71.11.32.6-1.40.6-0.61.3-1.31.3-1.3-1.6-1.3-1.41.3-0.9-0.1-1.21.4-1.6-0.1-0.2-0.91.3-1.3
Stereotopy head waving bouts, day 71.01.12.21.2-0.90.9-1.11.1-1.11.11.51.10.10.10.51.51.2-0.71.3-0.7-0.71.4-1.51.1
Stereotopy head waving duration, day 71.11.42.71.4-1.01.0-1.21.2-1.21.21.61.20.2-0.00.61.51.4-0.91.5-0.8-0.81.5-1.71.3
Locomotion velocity, session 80.00.00.00.0-0.00.0-0.10.1-0.10.1-0.10.10.2-0.20.0-0.10.1-0.1-0.10.10.10.10.10.1
Locomotion distance, session 81.21.73.2-1.41.4-1.41.3-1.31.3-1.3-1.6-1.3-0.40.2-0.7-1.2-1.51.1-1.81.21.2-1.61.6-1.4
Degree of sensitization distance0.60.61.50.8-1.21.2-0.80.8-0.80.80.70.80.2-0.10.40.50.9-0.60.6-0.8-0.81.0-0.70.8
Degree of sensitization stereotypy0.40.41.80.6-0.60.6-0.50.5-0.50.50.80.5-0.50.60.11.30.7-0.10.7-0.5-0.50.9-0.90.5
Condit. Reinf. active minus inactive responses0.20.31.1-0.30.7-0.70.3-0.30.3-0.3-0.2-0.30.6-0.7-0.0-1.0-0.4-0.0-0.20.70.7-0.60.7-0.3
Condit. Reinf. active-inactive response ratio0.20.31.40.30.1-0.1-0.40.4-0.40.40.40.41.1-1.20.5-0.90.2-0.70.50.10.1-0.10.10.4
Condit. Reinf. active responses0.60.71.4-0.91.2-1.20.7-0.70.7-0.7-0.8-0.70.0-0.1-0.4-1.0-0.90.6-0.81.21.2-1.01.2-0.8
Condit. Reinf. inactive responses2.12.53.6-1.81.6-1.61.7-1.71.7-1.7-1.8-1.7-1.61.5-1.2-0.0-1.71.9-1.91.21.1-1.51.5-1.8
Incentive salience index mean0.10.20.80.20.1-0.1-0.30.3-0.30.30.10.30.8-0.80.2-0.90.2-0.40.20.40.40.00.30.2
Condit. Reinf. lever presses0.20.30.80.5-0.40.4-0.70.7-0.70.70.30.70.9-0.90.3-0.80.6-0.70.30.10.10.60.10.6
Time in familiar zone, hab. session 10.50.51.0-0.60.8-0.80.5-0.50.5-0.5-0.5-0.50.1-0.2-0.2-1.0-0.70.3-0.71.01.0-0.91.0-0.6
Time in novel zone, hab. session 10.70.72.50.7-0.90.9-0.50.5-0.50.50.70.5-0.60.70.11.60.7-0.10.5-1.3-1.41.1-1.20.6
Total zone transitions, hab. session 10.30.41.1-0.70.5-0.50.7-0.70.7-0.7-0.8-0.7-0.70.7-0.50.1-0.60.7-1.00.00.0-0.50.5-0.7
Total locomotion distance, hab. session 10.00.00.1-0.00.3-0.30.1-0.10.1-0.1-0.2-0.10.2-0.20.1-0.1-0.1-0.1-0.2-0.1-0.1-0.2-0.1-0.0
Locomotion velocity, hab. session 10.00.00.10.10.2-0.2-0.00.0-0.00.0-0.10.00.2-0.20.10.10.0-0.2-0.2-0.3-0.2-0.1-0.30.1
Time in familiar zone, hab. session 20.30.30.80.4-0.40.4-0.50.5-0.50.50.50.50.8-0.90.5-0.80.3-0.70.50.30.30.0-0.10.4
Time in novel zone, hab. session 20.70.73.3-0.30.3-0.30.5-0.50.5-0.5-0.5-0.5-1.41.5-0.51.8-0.30.9-0.5-1.1-1.20.3-0.5-0.4
Total zone transitions, hab. session 20.30.41.4-0.70.5-0.50.6-0.60.6-0.6-0.8-0.60.2-0.3-0.3-1.2-0.60.3-0.80.60.6-0.81.1-0.6
Total locomotion distance, hab. session 20.20.20.6-0.40.6-0.60.5-0.50.5-0.5-0.6-0.50.4-0.5-0.0-0.8-0.50.1-0.60.30.3-0.70.5-0.4
Locomotion velocity, hab. session 20.10.20.9-0.30.5-0.50.3-0.30.3-0.3-0.4-0.30.6-0.70.1-1.0-0.3-0.1-0.40.40.4-0.60.5-0.2
Novel to familiar place preference ratio1.81.93.21.5-1.81.8-1.31.3-1.31.31.31.30.3-0.10.71.41.5-1.01.5-1.5-1.51.7-1.61.4
Novelty place preference1.41.52.61.2-1.61.6-1.11.1-1.11.11.11.10.00.20.51.51.3-0.81.3-1.5-1.51.5-1.51.2
Time in novel zone, NPP test1.31.43.11.1-1.61.6-1.01.0-1.01.01.01.0-0.30.50.41.81.2-0.61.2-1.6-1.61.5-1.61.1
Total zone transitions, NPP test1.31.94.0-1.41.6-1.61.3-1.31.3-1.3-1.6-1.3-0.1-0.1-0.7-1.7-1.40.9-1.61.51.5-1.52.0-1.3
Total locomotion distance, NPP test1.62.23.4-1.61.9-1.91.6-1.61.6-1.6-1.8-1.6-0.60.4-0.8-1.0-1.71.3-1.80.90.9-1.81.6-1.6
Locomotion velocity, NPP test0.91.32.2-1.21.5-1.51.2-1.21.2-1.2-1.4-1.2-0.1-0.1-0.5-1.2-1.30.8-1.31.01.0-1.41.4-1.2
Pavlov. Cond. lever latency0.20.31.50.10.1-0.10.2-0.20.2-0.2-0.0-0.2-0.40.40.11.2-0.10.1-0.1-1.2-1.20.0-0.90.0
Pavlov. Cond. magazine entry latency0.10.11.2-0.10.0-0.00.0-0.00.0-0.00.1-0.00.6-0.70.2-1.1-0.1-0.30.20.60.6-0.40.5-0.0
Pavlov. Cond. change in total contacts0.20.20.70.2-0.30.3-0.50.5-0.50.50.40.50.5-0.40.1-0.70.3-0.30.40.80.90.20.40.3
Pavlov. Cond. index score0.20.20.80.3-0.50.5-0.50.5-0.50.50.40.50.5-0.50.1-0.90.4-0.40.40.60.60.40.40.3
Pavlov. Cond. latency score0.20.31.20.2-0.50.5-0.40.4-0.40.40.30.40.6-0.60.1-1.10.4-0.40.40.80.80.30.60.3
Pavlov. Cond. lever contacts0.40.41.9-0.60.2-0.20.3-0.30.3-0.3-0.5-0.3-0.10.0-0.4-1.2-0.40.4-0.41.41.4-0.41.3-0.5
Pavlov. Cond. magazine entry number0.10.10.80.1-0.00.0-0.00.0-0.00.00.00.0-0.40.40.00.90.10.1-0.1-0.5-0.50.2-0.60.1
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.71.1-1.10.6-0.60.6-0.6-0.7-0.60.0-0.1-0.3-0.6-0.70.5-0.60.90.9-0.80.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.00.6-0.80.8-0.80.8-0.80.80.70.80.9-0.90.3-1.00.7-0.80.70.50.50.60.30.6
Pavlov. Cond. response bias0.20.31.8-0.30.1-0.10.1-0.10.1-0.1-0.1-0.10.5-0.6-0.0-1.3-0.2-0.1-0.01.01.0-0.40.9-0.2
Bone: apparent density8.213.520.14.0-4.14.1-4.14.1-4.14.14.24.14.0-3.82.8-0.73.9-4.54.2-1.6-1.43.1-3.04.1
Bone surface9.516.823.34.6-4.64.6-4.64.6-4.64.64.74.64.1-3.83.0-0.14.4-4.84.8-1.9-1.73.7-3.64.6
Bone volume7.112.117.23.8-3.83.8-3.93.9-3.93.94.13.93.5-3.32.6-0.33.7-4.14.1-1.6-1.53.1-3.03.9
Bone: connectivity density5.89.114.23.3-3.33.3-3.43.4-3.43.43.53.43.5-3.42.3-0.93.1-3.83.5-0.8-0.72.4-2.33.4
Bone: cortical apparent density0.30.40.9-0.60.6-0.60.7-0.70.7-0.7-0.8-0.7-0.90.9-0.40.8-0.60.8-0.8-0.3-0.4-0.40.1-0.6
Bone: cortical area8.312.518.03.9-4.14.1-4.04.0-4.04.04.14.03.1-2.82.40.24.0-3.94.2-1.6-1.53.6-3.04.0
Bone: cortical porosity1.21.33.1-1.01.1-1.11.3-1.31.3-1.3-0.9-1.3-1.81.8-0.71.2-1.11.3-0.8-0.7-0.8-0.90.0-1.1
Bone: cortical porosity1.61.74.0-1.21.4-1.41.5-1.51.5-1.5-1.1-1.5-2.02.0-0.81.2-1.31.5-1.0-0.7-0.7-1.00.2-1.3
Bone: cortical thickness3.45.67.82.5-2.62.6-2.82.8-2.82.82.72.82.5-2.31.5-0.72.7-2.72.8-0.3-0.32.3-1.42.6
Bone: cortical thickness0.30.40.90.4-0.70.7-0.60.6-0.60.60.40.60.9-0.90.3-0.90.5-0.60.40.50.60.40.40.5
Bone: cortical tissue density0.50.61.1-0.70.8-0.80.8-0.80.8-0.8-0.9-0.8-1.11.1-0.50.9-0.70.9-0.9-0.4-0.4-0.50.2-0.7
Bone: elastic displacement3.84.35.9-2.32.2-2.22.4-2.42.4-2.4-2.4-2.4-2.22.1-1.40.2-2.32.4-2.30.30.2-2.11.6-2.3
Bone: elastic work0.20.21.6-0.10.0-0.00.3-0.30.3-0.3-0.3-0.3-0.50.5-0.00.7-0.20.2-0.1-1.3-1.3-0.1-0.4-0.1
Bone: endosteal estimation6.113.217.54.1-4.14.1-3.93.9-3.93.94.03.92.4-2.02.41.94.0-3.74.1-3.1-3.03.8-4.24.1
Bone: endosteal perimeter5.711.716.43.9-4.04.0-3.83.8-3.83.84.03.82.5-2.12.21.23.9-3.64.1-2.2-2.13.6-3.43.8
Bone: final force8.013.018.04.0-4.04.0-4.14.1-4.14.14.04.13.7-3.42.6-0.24.0-4.24.1-1.7-1.63.4-3.04.1
Bone: final moment8.113.318.94.1-4.04.0-4.14.1-4.14.14.14.13.7-3.52.7-0.24.0-4.34.1-1.9-1.83.3-3.24.1
Bone: marrow area6.113.017.34.1-4.14.1-3.93.9-3.93.94.03.92.3-1.92.42.04.0-3.74.1-3.1-3.03.8-4.24.0
Bone: maximum diameter3.56.410.02.8-3.23.2-2.92.9-2.92.93.02.91.8-1.51.60.62.9-2.63.1-1.2-1.12.8-2.22.8
Bone: maximum force11.019.124.94.9-5.05.0-4.84.8-4.84.84.84.83.8-3.43.20.94.8-4.94.8-3.1-2.94.3-4.45.0
Bone: maximum moment11.119.325.05.0-4.94.9-4.84.8-4.84.84.84.83.9-3.53.20.94.8-5.04.9-3.2-3.14.2-4.55.0
Bone: minimum diameter7.614.019.94.2-4.34.3-4.24.2-4.24.24.34.22.6-2.22.41.64.2-3.94.5-2.7-2.64.0-3.94.2
Bone: periosteal estimation9.920.227.95.1-5.25.2-5.05.0-5.05.05.25.03.6-3.13.01.25.0-4.85.3-2.8-2.74.6-4.45.1
Bone: periosteal perimeter8.514.120.54.2-4.34.3-4.34.3-4.34.34.44.33.4-3.12.60.24.2-4.24.5-1.7-1.63.7-3.24.2
Bone: post-yield work6.69.014.43.4-3.43.4-3.13.1-3.13.13.23.11.6-1.32.02.23.3-2.93.2-2.9-2.83.2-3.83.3
Bone: stiffness13.321.027.15.2-5.25.2-5.15.1-5.15.15.15.14.0-3.63.30.95.1-5.15.1-3.0-2.94.5-4.55.2
Bone: tissue strength0.80.71.70.9-0.80.8-0.80.8-0.80.80.80.80.5-0.40.60.80.8-0.80.7-1.3-1.20.8-1.30.9
Bone: trabecular number4.87.413.12.9-2.82.8-2.92.9-2.92.93.22.93.6-3.62.3-1.42.7-3.63.1-0.5-0.41.7-1.93.0
Bone: trabecular spacing1.92.45.9-1.51.6-1.61.6-1.61.6-1.6-1.7-1.6-2.42.4-1.31.4-1.42.1-1.6-0.1-0.2-0.70.7-1.6
Bone: trabecular thickness0.20.31.9-0.40.0-0.00.3-0.30.3-0.3-0.2-0.30.5-0.6-0.0-1.4-0.4-0.0-0.20.70.7-0.70.9-0.4
Bone: trabecular tissue density0.30.41.3-0.20.1-0.10.4-0.40.4-0.4-0.3-0.4-1.11.1-0.31.1-0.20.6-0.1-1.1-1.10.1-0.3-0.3
Breakpoint value in progressive ratio session0.10.20.30.5-0.40.4-0.50.5-0.50.50.40.50.3-0.20.10.20.4-0.40.5-0.2-0.20.3-0.40.4
Distance traveled before self-admin0.91.02.4-1.00.6-0.61.0-1.01.0-1.0-1.3-1.0-1.51.6-0.80.8-0.91.3-1.2-0.2-0.2-0.60.4-1.0
Distance traveled after self-admin0.10.20.3-0.50.3-0.30.3-0.30.3-0.3-0.5-0.3-0.10.1-0.2-0.4-0.50.3-0.40.50.5-0.50.6-0.4
Delta time in closed arm before/after self-admin0.50.52.30.30.2-0.2-0.40.4-0.40.40.60.41.4-1.50.4-1.40.2-0.90.60.70.7-0.40.20.4
Delta time in open arm before/after self-admin3.23.04.7-2.01.6-1.61.9-1.91.9-1.9-2.1-1.9-2.12.0-1.30.3-1.92.2-2.10.50.5-1.51.6-2.0
Diff in mean of infusions in LGA sessions1.11.22.11.2-0.80.8-1.21.2-1.21.21.41.21.4-1.40.8-0.41.2-1.41.2-0.3-0.20.8-0.81.3
Extinction: sum of active levers before priming0.40.40.80.7-0.80.8-0.60.6-0.60.60.70.60.00.10.20.80.6-0.50.7-0.8-0.80.7-0.90.6
Active lever presses in extinction session 60.40.40.90.6-0.40.4-0.80.8-0.80.80.60.80.9-0.90.4-0.40.6-0.80.70.20.20.2-0.20.6
Delta distance traveled before/after self-admin0.30.31.50.10.1-0.1-0.30.3-0.30.30.30.31.1-1.20.4-1.20.1-0.60.30.70.8-0.20.40.2
Delta ambulatory time before/after self-admin0.10.10.80.0-0.00.0-0.20.2-0.20.20.10.20.6-0.70.2-0.90.0-0.30.10.50.5-0.10.40.1
Time in closed arm before self-admin1.51.73.11.4-1.51.5-1.41.4-1.41.41.31.40.20.10.71.61.4-0.91.2-1.2-1.21.6-1.81.3
Time in closed arm after self-admin0.50.51.00.8-0.70.7-0.80.8-0.80.80.90.80.6-0.50.50.30.7-0.80.9-0.6-0.60.5-1.00.8
Time in open arm before self-admin0.70.71.60.9-1.11.1-0.70.7-0.70.70.80.70.6-0.60.50.10.9-0.90.8-1.3-1.21.0-0.90.9
Time in open arm after self-admin0.20.20.5-0.50.3-0.30.5-0.50.5-0.5-0.6-0.5-0.70.7-0.40.3-0.40.6-0.6-0.2-0.2-0.10.3-0.5
Sum of active levers in priming session hrs 5-60.10.10.1-0.30.4-0.40.3-0.30.3-0.3-0.3-0.3-0.20.1-0.20.1-0.30.2-0.30.30.3-0.30.1-0.3
Time to tail flick, vehicle, before self-admin1.01.11.7-1.11.1-1.11.3-1.31.3-1.3-1.0-1.3-0.80.7-0.6-0.3-1.21.0-0.90.90.8-1.30.8-1.1
Time to tail flick, vehicle, after self-admin0.50.52.10.6-0.70.7-0.50.5-0.50.50.30.5-0.50.60.11.50.6-0.10.4-1.3-1.30.8-1.00.5
Time to tail flick, test, before self-admin0.30.30.5-0.60.6-0.60.7-0.70.7-0.7-0.7-0.7-0.40.3-0.3-0.2-0.70.6-0.7-0.1-0.1-0.60.4-0.6
Time to tail flick, test, after self-admin0.10.10.30.4-0.10.1-0.40.4-0.40.40.30.40.5-0.50.3-0.00.4-0.50.4-0.3-0.30.4-0.40.4
Delta time to tail flick, vehicle, before/after SA0.50.50.80.7-0.70.7-0.90.9-0.90.90.60.90.4-0.30.40.40.8-0.60.6-0.7-0.70.9-0.50.7
Delta time to tail flick, test, before/after SA0.20.20.30.4-0.50.5-0.40.4-0.40.40.50.40.3-0.30.20.10.5-0.40.5-0.1-0.10.6-0.30.4
Ambulatory time before self-admin3.03.25.5-1.91.4-1.41.9-1.91.9-1.9-2.2-1.9-2.32.3-1.40.7-1.92.3-2.20.20.1-1.51.3-2.0
Ambulatory time after self-admin1.21.32.3-1.30.8-0.81.2-1.21.2-1.2-1.5-1.2-1.51.5-0.90.3-1.21.5-1.40.30.3-1.01.0-1.3
Total heroin consumption2.32.85.61.7-2.12.1-1.51.5-1.51.51.51.5-0.00.30.71.91.7-1.11.5-2.4-2.42.0-2.21.6
Area under the delay curve1.01.12.51.0-1.21.2-1.11.1-1.11.10.91.11.6-1.60.8-1.01.0-1.30.90.10.20.8-0.31.1
Delay disc. indifference point, 0s delay1.21.32.01.2-1.41.4-1.11.1-1.11.11.31.10.6-0.50.80.61.3-1.01.4-1.1-1.01.4-1.31.2
Delay disc. indifference point, 16s delay1.01.02.21.1-1.51.5-1.11.1-1.11.11.01.10.9-0.80.6-0.11.2-1.01.0-0.5-0.51.2-0.71.1
Delay disc. indifference point, 2s delay1.01.11.51.2-1.11.1-1.21.2-1.21.21.11.20.9-0.80.80.41.2-1.21.1-0.6-0.61.0-1.21.2
Delay disc. indifference point, 24s delay1.21.21.91.2-1.41.4-1.31.3-1.31.31.21.30.9-0.80.70.21.2-1.21.1-0.4-0.41.2-1.01.2
Delay disc. indifference point, 4s delay0.50.52.60.4-0.40.4-0.50.5-0.50.50.30.51.5-1.60.6-1.50.4-0.90.30.50.60.10.30.5
Delay disc. indifference point, 8s delay2.62.75.11.6-1.71.7-1.81.8-1.81.81.61.82.3-2.21.2-1.21.7-2.01.60.00.11.4-0.71.7
Delay discount exponential model param0.91.02.5-0.91.1-1.11.1-1.11.1-1.1-0.8-1.1-1.61.6-0.81.1-1.01.2-0.8-0.2-0.3-0.70.2-1.0
Delay discount hyperbolic model param0.90.92.3-0.91.0-1.01.0-1.01.0-1.0-0.8-1.0-1.51.5-0.81.0-0.91.2-0.7-0.1-0.2-0.70.3-1.0
Fecal boli incidents, locomotor time 12.72.912.5-1.61.6-1.61.3-1.31.3-1.3-1.4-1.30.8-1.2-0.5-3.5-1.50.6-1.62.22.2-1.92.7-1.4
Change in fecal boli incidents, locomotor task1.11.12.41.2-1.21.2-1.01.0-1.01.01.11.00.3-0.20.71.11.1-0.91.0-1.2-1.21.0-1.51.1
Time >=10cm from walls, locomotor time 10.30.31.40.4-0.40.4-0.40.4-0.40.40.40.41.1-1.20.4-1.10.4-0.70.3-0.2-0.20.40.10.5
Bouts of movement, locomotor time 10.20.21.10.0-0.30.3-0.00.0-0.00.0-0.10.00.7-0.80.2-1.00.1-0.40.0-0.7-0.70.30.40.2
Total resting periods, locomotor time 10.20.21.4-0.50.3-0.30.4-0.40.4-0.4-0.6-0.40.4-0.5-0.1-1.2-0.40.1-0.5-0.2-0.2-0.30.9-0.4
Rest time, locomotor task time 10.30.31.5-0.60.4-0.40.5-0.50.5-0.5-0.6-0.50.2-0.4-0.3-1.2-0.50.3-0.70.40.4-0.51.0-0.5
Distance moved, locomotor task time 10.10.11.20.10.3-0.30.1-0.10.1-0.10.1-0.1-0.60.6-0.11.1-0.00.20.2-0.0-0.0-0.1-0.7-0.0
Vertical activity count, locomotor time 11.21.22.71.1-0.70.7-1.31.3-1.31.31.21.31.7-1.60.9-0.81.1-1.41.30.30.40.7-0.51.1
Time >=10cm from walls, locomotor time 20.40.40.8-0.70.5-0.50.7-0.70.7-0.7-0.7-0.7-0.50.4-0.3-0.5-0.60.7-0.80.20.2-0.60.9-0.7
Bouts of movement, locomotor time 22.52.74.11.8-2.02.0-1.71.7-1.71.71.61.70.7-0.51.01.31.8-1.41.6-1.7-1.71.9-2.01.8
Total resting periods, locomotor time 22.72.94.51.9-2.12.1-1.71.7-1.71.71.71.70.7-0.51.01.31.9-1.51.7-1.8-1.82.0-2.11.9
Rest time, locomotor task time 20.10.10.50.2-0.30.3-0.30.3-0.30.30.00.30.7-0.70.1-0.70.3-0.4-0.1-0.3-0.30.40.20.3
Distance moved, locomotor task time 20.20.20.4-0.40.5-0.50.5-0.50.5-0.5-0.3-0.5-0.70.7-0.20.5-0.50.5-0.10.00.0-0.5-0.1-0.4
Vertical activity count, locomotor time 20.10.10.30.2-0.50.5-0.30.3-0.30.30.30.30.1-0.00.20.00.3-0.10.4-0.2-0.20.4-0.10.2
Weight adjusted by age2.22.54.11.7-2.02.0-1.71.7-1.71.71.61.70.6-0.40.81.21.8-1.31.6-1.5-1.51.9-1.71.7
Seeking ratio, delayed vs. immediate footshock0.70.83.50.5-0.00.0-0.70.7-0.70.70.70.71.8-1.90.5-1.80.4-1.10.71.01.10.00.50.6
Locomotion in novel chamber0.40.51.00.9-0.70.7-0.80.8-0.80.80.90.80.5-0.40.40.50.9-0.70.9-0.4-0.41.0-0.90.9
Locomotion in novel chamber post-restriction0.20.21.30.2-0.80.8-0.10.1-0.10.10.10.1-0.10.10.20.20.3-0.10.1-1.1-1.10.6-0.40.3
Progressive ratio0.10.10.7-0.20.1-0.10.2-0.20.2-0.2-0.0-0.20.2-0.3-0.0-0.7-0.20.0-0.00.80.8-0.40.4-0.2
Food seeking constrained by brief footshock0.20.20.6-0.60.1-0.10.5-0.50.5-0.5-0.6-0.5-0.20.1-0.3-0.7-0.40.4-0.50.20.1-0.20.8-0.5
Seeking ratio, punishment vs. effort0.10.10.50.0-0.10.1-0.00.0-0.00.0-0.20.0-0.20.3-0.10.40.10.1-0.2-0.7-0.70.4-0.10.0
Run reversals in cocaine runway, females0.10.10.4-0.00.1-0.10.2-0.20.2-0.20.0-0.2-0.50.5-0.10.7-0.10.20.0-0.2-0.2-0.0-0.3-0.1
Run reversals in cocaine runway, males1.21.11.6-1.21.0-1.01.2-1.21.2-1.2-1.1-1.2-1.21.1-0.80.1-1.21.3-1.10.60.6-1.01.0-1.2
Latency to leave start box in cocaine runway0.00.00.1-0.10.0-0.00.1-0.10.1-0.10.0-0.1-0.10.1-0.00.1-0.10.10.00.30.3-0.0-0.2-0.1
Latency to leave start box in cocaine runway, F1.41.62.8-1.31.1-1.11.4-1.41.4-1.4-1.4-1.4-1.71.7-0.90.6-1.31.6-1.40.30.3-1.10.7-1.4
Latency to leave start box in cocaine runway, M1.71.62.61.4-1.11.1-1.41.4-1.41.41.51.41.6-1.60.9-0.51.3-1.61.50.10.21.1-1.01.4
Cd content in liver0.40.41.3-0.80.4-0.40.6-0.60.6-0.6-1.0-0.6-0.30.3-0.5-0.6-0.60.7-1.00.50.5-0.61.1-0.7
Co content in liver0.30.31.6-0.50.2-0.20.0-0.00.0-0.0-0.6-0.00.1-0.1-0.5-1.0-0.20.5-0.61.21.2-0.11.3-0.4
Cu content in liver0.81.01.71.0-0.70.7-1.31.3-1.31.30.81.31.2-1.10.5-0.51.1-1.10.8-0.5-0.51.1-0.31.0
Fe content in liver0.20.31.2-0.50.3-0.30.3-0.30.3-0.3-0.5-0.3-0.10.2-0.5-0.7-0.40.5-0.50.90.9-0.31.1-0.5
K content in liver0.40.41.20.5-0.50.5-0.70.7-0.70.70.40.71.1-1.10.4-1.00.6-0.70.40.20.20.50.20.6
Mg content in liver0.10.10.7-0.10.1-0.1-0.00.0-0.00.0-0.00.00.5-0.60.1-0.80.0-0.2-0.00.70.7-0.10.40.0
Mn content in liver0.20.21.10.2-0.00.00.1-0.10.1-0.10.3-0.1-0.40.50.11.00.10.00.2-1.0-1.00.3-0.60.2
Na content in liver0.00.00.2-0.10.1-0.1-0.00.0-0.00.0-0.50.0-0.20.2-0.20.1-0.00.2-0.5-0.2-0.20.10.2-0.1
Rb content in liver0.10.20.4-0.50.2-0.20.4-0.40.4-0.4-0.6-0.4-0.40.4-0.4-0.2-0.30.6-0.60.20.1-0.10.6-0.4
Se content in liver0.50.61.7-0.80.7-0.70.7-0.70.7-0.7-0.6-0.7-0.10.0-0.5-1.0-0.80.6-0.71.11.1-0.81.3-0.8
Sr content in liver0.60.51.30.7-1.11.1-0.80.8-0.80.80.80.80.5-0.30.4-0.10.8-0.70.8-0.2-0.20.8-0.30.7
Zn content in liver1.01.12.1-1.20.8-0.81.0-1.01.0-1.0-1.2-1.0-1.31.3-1.00.1-1.01.5-1.20.50.5-0.71.1-1.2