Cgnl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000054080 0.57 0.19 0.0e+00 0.34 0.37 0.37 0.37 7.3e-39 2.8e-43 2.8e-43 1.6e-43
2 Adipose mRNA stability ENSRNOG00000054080 0.09 0.06 2.6e-09 0.06 0.06 0.06 0.06 8.1e-07 1.2e-07 3.7e-07 5.8e-07
3 BLA gene expression ENSRNOG00000054080 0.13 0.08 3.1e-05 0.09 0.08 0.07 0.08 2.2e-05 3.3e-05 1.9e-04 6.5e-05
4 Brain gene expression ENSRNOG00000054080 0.29 0.15 1.5e-14 0.15 0.16 0.16 0.16 9.2e-14 1.1e-14 1.6e-14 2.7e-14
5 IL gene expression ENSRNOG00000054080 0.29 0.18 9.7e-03 0.12 0.02 0.04 0.07 1.1e-03 9.1e-02 4.6e-02 8.6e-03
6 Liver mRNA stability ENSRNOG00000054080 0.04 0.03 7.4e-03 0.02 0.01 0.01 0.01 5.4e-03 5.2e-02 6.4e-02 1.4e-02
7 NAcc gene expression ENSRNOG00000054080 0.33 0.21 1.3e-10 0.14 0.15 0.15 0.14 1.1e-10 4.0e-11 2.6e-11 6.3e-11
8 OFC gene expression ENSRNOG00000054080 0.37 0.19 5.7e-04 0.13 0.14 0.09 0.13 5.5e-04 3.7e-04 3.8e-03 4.6e-04
9 PL gene expression ENSRNOG00000054080 0.31 0.14 7.5e-14 0.16 0.19 0.19 0.19 1.7e-12 1.8e-14 1.6e-14 1.6e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail3.09.616.53.13.3-4.0-3.20.74.1-3.9-0.7-2.7
BMI without tail0.91.95.62.42.3-0.9-0.31.61.0-0.61.10.1
Body weight2.711.220.33.23.3-4.4-3.70.04.5-3.8-1.2-3.3
Epididymis fat weight0.20.40.70.50.50.50.70.8-0.4-0.20.90.8
Glucose0.30.41.11.11.0-0.10.20.90.1-0.20.80.3
Heart weight1.62.34.50.20.2-1.8-1.9-1.11.8-2.1-1.4-1.8
Left kidney weight1.13.05.52.22.3-2.1-1.40.92.1-2.10.2-1.0
Right kidney weight1.02.95.12.02.0-2.2-1.80.22.2-1.5-0.4-1.5
Tail length0.82.46.41.10.91.41.51.3-1.32.51.71.6
Length with tail0.31.22.51.61.5-1.3-1.10.11.3-0.2-0.0-0.9
Length without tail2.86.011.01.11.2-3.3-3.1-1.23.2-2.6-1.9-3.0
Liver weight, left0.91.53.11.51.60.40.91.8-0.4-0.01.61.1
Liver weight, right0.81.33.71.91.9-0.40.11.40.3-0.41.20.4
Parametrial fat weight1.53.05.20.70.51.82.01.5-1.72.31.92.1
Retroperitoneal fat weight0.10.30.80.40.50.10.40.6-0.1-0.90.60.5
Intraocular pressure0.00.00.10.30.2-0.1-0.10.10.3-0.20.0-0.1
Extensor digitorum longus weight3.112.624.94.85.0-4.3-3.21.74.3-3.00.3-2.5
Soleus weight6.017.540.56.26.4-4.7-3.22.74.7-3.11.1-2.3
Tibialis anterior weight4.415.040.36.26.3-3.9-2.33.33.9-2.31.8-1.4
Tibia length0.41.12.3-0.9-0.7-0.7-1.1-1.20.7-1.5-1.3-1.1
Number of licking bursts1.21.52.8-0.9-1.01.61.40.2-1.61.70.61.2
Food consumed during 24 hour testing period0.91.12.41.31.30.40.81.5-0.40.41.41.0
Times rat made contact with spout0.20.30.4-0.3-0.20.60.70.3-0.60.60.40.6
Mean time between licks in bursts0.30.40.7-0.7-0.6-0.5-0.6-0.80.5-0.3-0.8-0.7
Mean num. licks in bursts0.40.51.10.70.8-0.8-0.60.30.8-1.1-0.0-0.5
Std. dev. time between licks in bursts2.12.54.30.20.3-2.1-2.1-1.12.1-1.3-1.5-2.0
Water consumed over 24 hours0.20.20.4-0.7-0.60.50.4-0.2-0.50.1-0.00.3
Indifference point 0 sec0.50.81.81.01.00.50.81.3-0.40.61.20.9
Indifference point AUC0.50.50.9-0.5-0.5-0.7-0.8-0.90.7-0.6-1.0-0.8
Indifference point function ln k0.50.71.71.21.20.10.51.3-0.1-0.11.10.6
Indifference point function log k0.50.71.71.21.20.10.51.3-0.1-0.11.10.6
Delay discounting total patch changes 0 sec0.61.02.01.11.10.50.81.4-0.40.81.30.9
Delay discounting total patch changes 12 sec0.10.10.3-0.4-0.30.20.1-0.1-0.10.5-0.10.1
Delay discounting total patch changes 18 sec0.00.00.10.20.10.10.10.3-0.0-0.20.20.2
Delay discounting total patch changes 24 sec0.40.61.40.60.60.50.60.8-0.51.20.80.7
Delay discounting total patch changes 6 sec0.10.10.30.50.5-0.2-0.00.40.2-0.00.30.1
Delay discounting time to switch 0 sec0.60.92.7-1.7-1.60.70.3-1.1-0.70.1-0.70.1
Delay discounting water rate 0 sec0.91.54.12.02.0-0.9-0.31.40.9-0.80.9-0.0
Delay discounting water rate 12 sec2.23.39.53.12.9-0.40.42.50.30.62.00.7
Delay discounting water rate 18 sec0.30.41.01.01.00.20.20.7-0.10.80.70.4
Delay discounting water rate 24 sec0.50.61.61.00.70.50.60.9-0.51.20.90.6
Delay discounting water rate 6 sec0.50.72.31.51.4-0.4-0.11.10.4-0.10.70.1
Locomotor activity1.82.97.42.72.7-1.9-1.31.01.9-0.10.5-1.0
Locomotor testing distance1.01.74.62.12.1-1.4-0.81.01.4-0.40.6-0.6
Locomotor testing rearing0.71.02.31.51.4-1.2-0.80.51.2-0.80.1-0.7
Light reinforcement 12.34.27.31.82.0-2.6-2.30.22.6-2.7-0.7-1.9
Light reinforcement 20.20.31.2-0.5-0.40.60.4-0.1-0.61.10.10.4
Reaction time number correct0.71.02.91.71.6-1.0-0.60.81.0-0.60.5-0.4
Reaction time mean minus median1.31.73.7-0.1-0.21.61.60.6-1.61.91.11.6
Reaction time mean minus median AUC2.83.56.0-0.3-0.42.42.31.1-2.42.41.62.3
Reaction time num false alarms0.81.02.5-0.4-0.41.21.20.4-1.21.60.71.2
Reaction time num false alarms AUC1.31.83.20.20.21.51.61.2-1.41.81.41.7
Reaction time trials correct on left0.71.02.91.71.6-1.0-0.60.81.0-0.60.5-0.4
Reaction time trials on left0.71.03.21.81.7-0.9-0.50.91.0-0.40.5-0.3
Reaction time mean2.33.17.7-1.5-1.62.21.7-0.4-2.22.80.41.5
Reaction time mean AUC2.43.29.2-1.2-1.32.31.8-0.2-2.33.00.61.7
Median of all reaction times2.22.96.1-1.9-2.02.01.4-0.9-2.12.5-0.01.2
Reaction time omissions0.40.50.90.80.80.40.60.9-0.40.60.90.7
Reaction time false alarm rate1.41.93.4-0.9-0.81.71.70.4-1.81.80.91.6
Reaction time premature initiation rate0.50.71.71.31.2-0.8-0.40.80.8-0.90.4-0.3
Reaction time premature initiations1.01.53.82.01.8-1.1-0.61.11.2-1.10.6-0.4
Std. dev. reaction times2.02.76.0-0.8-0.82.11.90.3-2.12.41.01.9
Reaction time trials completed0.71.03.21.81.7-0.9-0.50.91.0-0.40.5-0.3
Reaction time trials AUC0.60.92.61.61.5-0.9-0.50.81.0-0.60.4-0.3
Social response proportion1.71.85.1-0.8-0.5-1.3-1.4-1.11.3-2.3-1.4-1.4
Social responses0.10.10.20.20.1-0.3-0.3-0.10.3-0.5-0.2-0.3
Social time0.60.81.40.50.50.91.11.1-0.90.61.21.1
Conditioned locomotion1.21.42.2-0.8-0.6-1.1-1.4-1.41.2-1.1-1.5-1.4
Cocaine response after cond. corrected1.31.44.02.01.9-0.30.21.60.30.41.30.5
Cocaine response after cond. not corrected0.70.82.01.41.4-0.10.31.20.20.51.00.4
Cocaine response before conditioning0.70.82.1-1.4-1.40.0-0.4-1.3-0.0-0.4-1.1-0.6
Saline control response1.11.42.40.0-0.01.51.51.0-1.50.91.31.5
Condit. Reinf. active minus inactive responses1.61.93.41.41.4-1.9-1.50.11.8-1.6-0.4-1.4
Condit. Reinf. active-inactive response ratio0.70.81.50.70.8-1.2-0.90.01.1-1.2-0.3-0.9
Condit. Reinf. active responses1.82.55.00.80.8-2.0-1.9-0.62.0-2.2-1.1-1.8
Condit. Reinf. inactive responses0.81.01.7-0.5-0.4-0.8-1.1-1.10.9-1.3-1.2-1.1
Condit. Reinf. lever presses0.30.41.0-1.0-1.00.0-0.3-0.9-0.0-0.3-0.8-0.4
Condit. Reinf. lever reinforcers received1.72.44.80.40.5-1.9-1.9-0.91.9-2.2-1.3-1.8
Pavlov. Cond. lever latency0.60.91.81.11.10.40.81.3-0.40.51.30.9
Pavlov. Cond. magazine entry latency1.21.43.6-1.8-1.91.30.7-1.0-1.30.9-0.50.5
Pavlov. Cond. change in total contacts0.30.41.0-1.0-1.00.0-0.3-0.9-0.0-0.4-0.8-0.4
Pavlov. Cond. index score0.40.51.5-1.2-1.20.2-0.2-1.0-0.20.1-0.8-0.3
Pavlov. Cond. latency score0.30.30.9-1.0-0.90.2-0.1-0.8-0.20.1-0.6-0.2
Pavlov. Cond. lever contacts0.50.71.4-0.8-0.8-0.5-0.8-1.20.5-0.5-1.1-0.9
Pavlov. Cond. magazine entry number1.11.43.31.71.8-1.3-0.80.91.3-1.00.4-0.5
Pavlov. Cond. intertrial magazine entries0.40.51.31.11.10.00.41.1-0.00.20.90.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.8-1.3-1.30.2-0.2-1.2-0.20.1-0.9-0.4
Pavlov. Cond. response bias1.21.63.6-1.6-1.6-0.3-0.9-1.90.3-0.4-1.7-1.1
Conditioned reinforcement - actives0.20.20.4-0.1-0.00.60.60.3-0.60.20.40.6
Conditioned reinforcement - inactives0.30.40.7-0.1-0.10.80.70.3-0.80.70.50.6
Conditioned locomotion1.72.03.6-1.3-1.3-0.9-1.3-1.90.9-1.6-1.8-1.4
Intermittent access intake day 1-15 change2.12.13.8-0.3-0.31.81.91.0-1.81.51.41.9
Intermittent access intake escalation2.42.44.3-0.4-0.41.92.11.0-1.91.61.52.0
Intermittent access intake escalation 20.90.91.40.20.21.01.20.9-1.01.01.11.2
Intermitt. access day 1 inactive lever presses0.50.51.4-1.2-1.00.80.7-0.1-0.8-0.50.10.6
Intermitt. access day 15 inactive lever presses1.31.43.9-0.9-0.8-0.9-1.1-1.20.9-2.0-1.3-1.1
Intermitt. access escalation Index2.22.07.60.70.8-1.7-1.30.01.6-2.8-0.5-1.2
Intermittent access day 1 total infusions0.70.81.7-0.6-0.61.31.00.2-1.31.10.40.8
Intermittent access day 15 total infusions2.22.44.2-1.0-1.02.01.90.4-2.12.00.91.7
Intermittent access terminal intake (last 3 days)1.01.02.7-0.9-1.01.30.9-0.3-1.31.70.10.7
Intermittent access total infusions2.93.26.5-0.2-0.32.22.11.0-2.22.51.52.0
Intermittent access day 1 locomotion1.01.02.1-1.4-1.41.30.9-0.4-1.30.3-0.10.7
Intermittent access day 15 total locomotion0.50.51.5-1.2-1.20.70.5-0.5-0.80.0-0.20.4
Intermittent access total locomotion0.40.50.90.0-0.01.00.90.6-1.00.30.70.9
Intermittent access standard deviation1.71.83.5-0.6-0.51.71.60.7-1.71.91.01.6
Cocaine induced anxiety0.20.30.6-0.7-0.70.2-0.2-0.8-0.2-0.0-0.6-0.4
Post-drug Anxiety0.70.72.1-1.4-1.50.70.4-0.8-0.70.4-0.50.1
Baseline Anxiety0.10.10.2-0.4-0.40.30.50.1-0.30.10.20.5
Lifetime Intake2.52.86.0-0.3-0.52.11.90.8-2.12.51.31.9
Incentive Sensitization - Responses0.90.93.00.20.3-1.1-1.0-0.31.1-1.7-0.6-1.1
Incentive Sensitization - Breakpoint0.90.93.20.00.1-1.0-1.0-0.41.0-1.8-0.7-1.1
Progressive ratio test 1 active lever presses1.11.21.90.50.31.31.20.8-1.31.41.21.3
Progressive ratio test 1 breakpoint0.90.91.70.0-0.11.31.10.4-1.31.20.81.1
Progressive ratio test 1 inactive lever presses3.43.76.9-0.5-0.62.62.51.2-2.61.51.72.4
Progressive ratio test 2 active lever presses0.20.20.30.30.30.50.50.5-0.40.30.50.4
Progressive ratio test 2 breakpoint0.30.40.60.60.60.50.60.8-0.50.50.80.6
Progressive ratio test 2 inactive lever presses0.50.61.2-1.1-1.11.00.6-0.3-0.90.4-0.10.4
Total sessions with >9 infusions2.12.33.50.30.11.91.81.1-1.91.81.51.9
Short access day 1 total inactive lever presses2.42.64.20.50.51.72.01.7-1.71.61.92.0
Short access day 10 total inactive lever presses1.11.22.2-0.7-0.51.41.50.7-1.5-0.10.91.4
Short access day 1 total infusions1.01.12.1-0.1-0.31.51.30.6-1.50.80.91.3
Short access day 10 total infusions1.82.04.9-0.3-0.41.81.60.8-1.82.21.01.5
Short access total infusions2.93.26.2-0.4-0.62.32.10.9-2.42.51.32.1
Short access day 1 locomotion0.20.20.40.10.10.60.50.4-0.6-0.20.50.6
Short access day 10 total locomotion0.60.71.20.60.50.81.01.0-0.80.21.11.0
Short access total locomotion1.21.22.5-0.5-0.61.61.40.4-1.60.80.81.3
Compulsive drug intake0.30.30.60.80.8-0.3-0.00.50.30.70.40.1
One hour access (0.3 mA shock)0.10.10.90.10.10.30.10.0-0.30.90.20.2
One hour access (shock baseline)0.30.30.6-0.8-0.70.80.5-0.3-0.8-0.0-0.00.3
Number of responses in last shaping day0.10.10.3-0.2-0.30.60.5-0.1-0.5-0.30.20.4
Context. condit. distance diff. score0.60.71.8-1.3-1.30.1-0.4-1.2-0.0-0.6-1.0-0.5
Locomotion velocity, session 11.92.14.51.81.80.51.12.1-0.50.61.91.3
Locomotion distance, session 10.70.91.5-0.2-0.21.21.20.6-1.21.00.91.1
Locomotion velocity, session 20.20.30.70.60.60.20.40.8-0.2-0.20.70.5
Locomotion distance, session 20.30.40.80.70.70.30.60.9-0.30.00.90.6
Locomotion velocity, session 32.83.24.90.60.62.02.11.9-1.91.82.12.2
Locomotion distance, session 31.21.32.5-1.2-1.31.61.2-0.1-1.51.20.31.1
Stereotopy head waving bouts, day 30.20.20.70.80.9-0.3-0.00.70.3-0.20.50.1
Stereotopy head waving duration, day 30.30.41.10.91.0-0.20.10.90.2-0.30.70.2
Locomotion velocity, session 70.91.02.0-1.1-1.11.41.0-0.2-1.41.00.20.9
Locomotion distance, session 71.41.73.2-1.0-1.01.81.60.3-1.81.40.71.5
Stereotopy head waving bouts, day 70.60.71.51.21.20.10.51.2-0.10.21.10.6
Stereotopy head waving duration, day 71.01.22.51.41.30.50.91.6-0.50.41.51.0
Locomotion velocity, session 80.60.71.41.00.90.50.71.2-0.50.41.10.8
Locomotion distance, session 80.20.30.6-0.8-0.70.80.5-0.2-0.7-0.1-0.00.4
Degree of sensitization distance0.10.10.3-0.2-0.10.40.40.2-0.40.60.20.4
Degree of sensitization stereotypy0.40.51.11.01.00.10.41.0-0.10.10.90.5
Condit. Reinf. active minus inactive responses2.02.23.3-0.8-0.7-1.4-1.7-1.71.4-1.6-1.8-1.8
Condit. Reinf. active-inactive response ratio2.12.23.9-1.4-1.3-1.1-1.5-2.01.1-1.3-2.0-1.6
Condit. Reinf. active responses0.50.61.10.20.2-1.0-1.1-0.61.0-0.6-0.8-1.0
Condit. Reinf. inactive responses1.11.42.21.41.30.50.81.5-0.41.51.41.0
Incentive salience index mean2.22.74.0-0.7-0.7-1.6-1.9-1.81.7-1.7-2.0-2.0
Condit. Reinf. lever presses1.01.42.1-0.6-0.6-1.1-1.4-1.41.1-1.0-1.5-1.4
Time in familiar zone, hab. session 10.60.61.0-0.2-0.2-0.8-0.9-0.70.8-1.0-0.9-0.9
Time in novel zone, hab. session 10.60.61.8-0.1-0.10.90.90.5-0.91.40.60.8
Total zone transitions, hab. session 11.01.32.3-0.1-0.11.41.51.0-1.51.01.21.5
Total locomotion distance, hab. session 10.40.50.90.10.10.90.90.7-0.90.50.81.0
Locomotion velocity, hab. session 10.30.50.80.40.30.70.90.8-0.70.30.90.9
Time in familiar zone, hab. session 20.20.20.30.10.10.50.50.4-0.50.50.50.5
Time in novel zone, hab. session 20.00.00.1-0.3-0.30.0-0.0-0.3-0.00.0-0.2-0.1
Total zone transitions, hab. session 20.50.71.20.30.3-1.0-1.1-0.61.0-1.0-0.8-1.0
Total locomotion distance, hab. session 21.31.72.80.40.4-1.6-1.7-0.81.6-1.5-1.1-1.6
Locomotion velocity, hab. session 21.11.52.50.10.2-1.4-1.6-0.91.5-1.5-1.2-1.5
Novel to familiar place preference ratio0.91.01.90.50.7-1.4-1.2-0.31.3-1.1-0.6-1.1
Novelty place preference1.01.01.90.50.7-1.4-1.2-0.31.3-1.2-0.6-1.2
Time in novel zone, NPP test0.80.91.70.70.8-1.3-1.1-0.11.3-1.0-0.4-1.0
Total zone transitions, NPP test0.10.10.20.40.4-0.4-0.30.10.5-0.5-0.0-0.3
Total locomotion distance, NPP test0.20.20.70.90.9-0.3-0.00.60.3-0.00.50.1
Locomotion velocity, NPP test0.10.20.30.60.60.00.20.60.00.20.50.3
Pavlov. Cond. lever latency0.70.91.50.1-0.01.21.20.8-1.20.91.01.2
Pavlov. Cond. magazine entry latency7.69.916.9-2.2-2.1-2.7-3.5-4.12.7-2.2-4.1-3.7
Pavlov. Cond. change in total contacts3.03.24.9-0.9-0.8-1.8-2.1-2.11.9-1.4-2.2-2.2
Pavlov. Cond. index score2.83.66.5-1.5-1.5-1.5-2.0-2.51.6-1.2-2.5-2.2
Pavlov. Cond. latency score2.12.64.4-1.1-1.0-1.5-1.8-2.11.5-1.1-2.1-1.9
Pavlov. Cond. lever contacts1.21.42.2-0.6-0.5-1.2-1.4-1.31.3-0.8-1.4-1.5
Pavlov. Cond. magazine entry number5.56.912.92.22.22.02.73.6-2.11.63.52.9
Pavlov. Cond. intertrial magazine entries1.82.13.31.00.81.31.61.7-1.31.31.81.7
Pavlov. Cond. lever-magazine prob. diff.3.03.86.5-1.4-1.3-1.7-2.2-2.51.7-1.3-2.5-2.3
Pavlov. Cond. response bias5.16.310.7-1.8-1.7-2.2-2.8-3.22.2-1.7-3.3-3.0
Bone: apparent density0.30.51.0-1.0-0.9-0.2-0.4-1.00.1-0.3-0.9-0.6
Bone surface0.00.10.20.30.4-0.4-0.3-0.00.4-0.0-0.1-0.3
Bone volume0.10.10.2-0.00.0-0.4-0.4-0.30.4-0.4-0.3-0.4
Bone: connectivity density0.40.71.5-0.9-0.91.00.8-0.2-1.01.20.10.7
Bone: cortical apparent density0.30.40.7-0.5-0.70.90.7-0.0-0.90.70.20.6
Bone: cortical area0.00.00.0-0.1-0.1-0.2-0.2-0.20.1-0.2-0.2-0.2
Bone: cortical porosity0.50.51.2-1.1-1.10.1-0.3-1.1-0.0-0.5-0.9-0.4
Bone: cortical porosity1.21.32.7-1.6-1.6-0.1-0.6-1.60.2-0.8-1.4-0.8
Bone: cortical thickness0.40.61.8-1.3-1.30.50.2-0.9-0.50.3-0.6-0.0
Bone: cortical thickness0.40.40.9-0.7-0.80.80.6-0.4-0.81.0-0.00.5
Bone: cortical tissue density0.30.40.8-0.5-0.70.90.7-0.0-0.90.70.20.6
Bone: elastic displacement0.40.40.80.30.4-0.9-0.9-0.40.9-0.6-0.5-0.8
Bone: elastic work1.21.62.3-0.4-0.4-1.3-1.5-1.41.3-1.2-1.5-1.5
Bone: endosteal estimation0.71.64.52.12.1-1.2-0.61.21.2-0.60.7-0.3
Bone: endosteal perimeter1.53.15.32.12.2-2.3-1.80.42.3-1.5-0.2-1.5
Bone: final force0.50.81.50.70.6-1.2-1.1-0.31.2-0.9-0.6-1.0
Bone: final moment0.40.61.00.30.2-1.0-1.0-0.51.0-0.9-0.7-1.0
Bone: marrow area0.81.64.62.12.1-1.2-0.71.21.2-0.70.7-0.4
Bone: maximum diameter0.71.23.61.91.9-1.0-0.61.01.0-0.50.6-0.3
Bone: maximum force0.71.22.20.70.7-1.5-1.4-0.41.5-1.2-0.7-1.3
Bone: maximum moment0.50.91.50.30.3-1.2-1.2-0.61.2-1.1-0.8-1.2
Bone: minimum diameter0.51.01.5-0.5-0.5-1.0-1.2-1.11.0-0.7-1.2-1.2
Bone: periosteal estimation0.50.92.51.51.6-1.0-0.60.81.0-0.60.4-0.4
Bone: periosteal perimeter0.61.12.81.61.7-1.1-0.70.71.1-0.60.4-0.5
Bone: post-yield work0.00.10.10.40.3-0.3-0.20.10.3-0.3-0.0-0.2
Bone: stiffness0.71.22.71.71.50.10.61.5-0.10.71.30.8
Bone: tissue strength0.60.61.4-1.1-1.20.80.6-0.5-0.80.6-0.20.4
Bone: trabecular number0.40.61.8-1.4-1.30.40.1-1.0-0.50.3-0.7-0.1
Bone: trabecular spacing0.10.10.20.10.10.40.40.4-0.40.10.40.5
Bone: trabecular thickness0.10.10.2-0.4-0.30.40.3-0.1-0.40.10.10.3
Bone: trabecular tissue density2.23.08.32.82.9-1.6-0.81.81.6-1.31.0-0.4
Breakpoint value in progressive ratio session0.20.20.50.50.4-0.7-0.5-0.10.70.3-0.2-0.4
Distance traveled before self-admin0.00.00.10.10.1-0.10.00.0-0.1-0.20.10.0
Distance traveled after self-admin1.21.32.91.71.70.10.61.60.00.51.40.8
Delta time in closed arm before/after self-admin0.70.64.7-0.1-0.1-0.6-0.5-0.10.5-2.2-0.4-0.5
Delta time in open arm before/after self-admin2.22.14.1-0.6-0.72.01.70.5-1.92.01.01.6
Diff in mean of infusions in LGA sessions1.51.73.30.10.1-1.5-1.8-1.11.5-1.2-1.5-1.7
Extinction: sum of active levers before priming2.12.14.30.60.41.41.71.3-1.42.11.61.7
Active lever presses in extinction session 60.00.00.00.1-0.00.10.10.2-0.1-0.10.10.1
Delta distance traveled before/after self-admin1.21.22.91.71.7-0.00.51.60.20.61.30.6
Delta ambulatory time before/after self-admin0.70.71.71.31.20.00.51.20.00.71.10.6
Time in closed arm before self-admin0.80.91.6-0.9-0.8-0.6-0.9-1.30.60.9-1.2-0.9
Time in closed arm after self-admin0.10.10.1-0.1-0.1-0.4-0.4-0.20.30.2-0.3-0.3
Time in open arm before self-admin1.01.04.51.11.2-0.6-0.11.10.4-2.10.70.1
Time in open arm after self-admin0.91.01.90.10.11.31.41.0-1.20.31.21.3
Sum of active levers in priming session hrs 5-60.30.30.50.40.20.50.50.5-0.50.70.60.5
Time to tail flick, vehicle, before self-admin0.10.10.40.10.1-0.4-0.3-0.00.4-0.6-0.2-0.3
Time to tail flick, vehicle, after self-admin0.40.43.4-0.2-0.1-0.2-0.20.00.1-1.8-0.1-0.2
Time to tail flick, test, before self-admin2.32.34.4-1.5-1.5-0.9-1.4-2.11.1-1.0-2.0-1.6
Time to tail flick, test, after self-admin2.02.14.2-0.9-0.92.11.70.5-2.01.50.91.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.5-0.50.30.1-0.2-0.3-0.3-0.20.0
Delta time to tail flick, test, before/after SA3.22.84.10.60.61.92.01.7-1.91.71.92.0
Ambulatory time before self-admin0.20.20.9-0.3-0.40.20.2-0.2-0.30.9-0.00.2
Ambulatory time after self-admin1.01.11.71.31.20.30.81.3-0.41.31.30.9
Total heroin consumption0.81.02.71.61.6-0.50.11.30.50.31.00.3
Area under the delay curve1.61.73.1-0.7-0.6-1.2-1.4-1.31.2-1.7-1.5-1.5
Delay disc. indifference point, 0s delay0.70.71.3-0.9-0.9-0.5-0.8-1.20.5-0.4-1.1-0.9
Delay disc. indifference point, 16s delay1.51.52.5-1.2-1.1-0.8-1.2-1.60.8-1.1-1.6-1.3
Delay disc. indifference point, 2s delay0.10.10.3-0.4-0.50.20.1-0.3-0.20.6-0.20.0
Delay disc. indifference point, 24s delay0.40.40.7-0.8-0.7-0.3-0.4-0.70.2-0.8-0.7-0.5
Delay disc. indifference point, 4s delay1.41.52.5-1.1-1.0-0.9-1.2-1.60.9-1.2-1.6-1.3
Delay disc. indifference point, 8s delay1.01.03.2-0.00.1-1.2-1.1-0.51.2-1.8-0.8-1.0
Delay discount exponential model param1.21.32.30.50.41.11.31.1-1.11.51.31.3
Delay discount hyperbolic model param0.90.91.50.60.50.91.01.0-0.91.21.11.1
Fecal boli incidents, locomotor time 10.30.30.7-0.4-0.4-0.4-0.6-0.80.4-0.5-0.7-0.7
Change in fecal boli incidents, locomotor task0.90.92.21.11.10.30.81.5-0.30.21.30.9
Time >=10cm from walls, locomotor time 10.50.50.90.20.1-0.8-0.9-0.60.9-0.3-0.7-0.9
Bouts of movement, locomotor time 10.20.20.60.60.5-0.2-0.10.40.2-0.80.2-0.1
Total resting periods, locomotor time 10.10.10.30.50.40.00.10.4-0.1-0.40.30.1
Rest time, locomotor task time 10.10.10.3-0.1-0.20.50.30.1-0.6-0.00.10.3
Distance moved, locomotor task time 10.10.10.3-0.2-0.10.30.40.3-0.20.50.30.4
Vertical activity count, locomotor time 10.10.10.3-0.4-0.3-0.3-0.4-0.40.4-0.2-0.4-0.5
Time >=10cm from walls, locomotor time 20.10.10.3-0.1-0.0-0.2-0.3-0.10.3-0.5-0.2-0.3
Bouts of movement, locomotor time 20.40.41.41.21.1-0.30.00.90.3-0.20.60.1
Total resting periods, locomotor time 20.60.61.91.41.2-0.10.21.10.1-0.10.90.3
Rest time, locomotor task time 20.20.20.3-0.3-0.40.60.60.2-0.6-0.40.20.5
Distance moved, locomotor task time 20.20.20.50.20.30.30.50.7-0.30.70.60.5
Vertical activity count, locomotor time 20.70.82.4-0.5-0.51.01.00.3-1.11.50.50.8
Weight adjusted by age2.32.67.72.82.7-1.3-0.51.51.3-1.01.1-0.2
Seeking ratio, delayed vs. immediate footshock0.40.40.70.80.9-0.8-0.50.40.8-0.60.1-0.4
Locomotion in novel chamber0.50.62.1-0.9-0.90.80.5-0.5-0.81.4-0.20.3
Locomotion in novel chamber post-restriction0.60.71.9-0.7-0.6-0.5-0.7-0.80.5-1.4-0.9-0.9
Progressive ratio2.63.04.8-1.6-1.3-1.2-1.7-2.01.2-2.2-2.1-1.9
Food seeking constrained by brief footshock1.31.63.81.51.60.31.02.0-0.40.61.71.2
Seeking ratio, punishment vs. effort4.05.09.93.02.80.51.53.1-0.61.72.91.9
Run reversals in cocaine runway, females0.20.20.40.30.40.50.50.6-0.5-0.30.60.5
Run reversals in cocaine runway, males0.50.40.80.70.60.30.70.9-0.30.50.90.7
Latency to leave start box in cocaine runway0.80.92.51.31.3-0.8-0.50.80.8-1.60.4-0.3
Latency to leave start box in cocaine runway, F0.40.41.40.70.7-0.10.30.90.1-1.20.70.3
Latency to leave start box in cocaine runway, M1.31.32.01.31.3-1.4-1.20.11.4-1.4-0.2-1.0
Cd content in liver0.80.91.3-0.5-0.5-0.9-1.1-1.10.8-1.0-1.2-1.1
Co content in liver2.12.53.8-0.8-0.7-1.5-1.8-1.71.4-2.0-1.8-1.9
Cu content in liver1.11.32.10.10.2-1.4-1.5-0.91.4-1.3-1.1-1.4
Fe content in liver2.02.44.5-0.1-0.21.91.91.0-1.92.11.41.8
K content in liver0.80.81.41.11.2-1.2-0.90.21.2-0.7-0.1-0.7
Mg content in liver2.02.13.61.51.6-1.9-1.50.21.9-1.5-0.3-1.3
Mn content in liver0.40.41.0-0.1-0.1-0.7-0.7-0.50.6-1.0-0.6-0.8
Na content in liver0.80.92.71.61.6-0.50.01.20.50.40.90.2
Rb content in liver1.01.23.11.71.7-0.10.41.60.00.21.30.6
Se content in liver0.60.71.4-0.4-0.51.11.00.3-1.11.20.60.9
Sr content in liver0.30.30.5-0.4-0.3-0.5-0.6-0.70.5-0.5-0.7-0.7
Zn content in liver2.42.64.3-1.3-1.2-1.3-1.7-2.11.3-1.5-2.1-1.8