Thap12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000053923 0.1 0.08 4.8e-05 0.03 0.03 0.03 0.03 3.2e-04 1.7e-04 9.7e-05 1.4e-04
2 Adipose mRNA stability ENSRNOG00000053923 0.09 0.05 4.0e-08 0.04 0.05 0.05 0.05 8.5e-05 2.1e-06 4.6e-06 3.4e-06
3 BLA gene expression ENSRNOG00000053923 0.21 0.14 2.6e-05 0.1 0.09 0.08 0.08 6.7e-06 2.1e-05 4.2e-05 5.7e-05
4 Brain gene expression ENSRNOG00000053923 0.3 0.11 0.0e+00 0.2 0.21 0.21 0.21 9.9e-19 2.2e-19 5.5e-19 3.5e-19
5 Brain mRNA stability ENSRNOG00000053923 0.15 0.08 4.1e-11 0.13 0.13 0.13 0.13 2.8e-12 6.5e-12 7.7e-12 3.1e-12
6 IL gene expression ENSRNOG00000053923 0.44 0.21 5.1e-04 0.05 0.02 -0 0.06 2.1e-02 1.3e-01 3.8e-01 1.7e-02
7 NAcc gene expression ENSRNOG00000053923 0.11 0.07 7.4e-08 0.1 0.1 0.1 0.1 7.8e-08 3.0e-08 1.3e-07 5.4e-08
8 NAcc mRNA stability ENSRNOG00000053923 0.12 0.06 4.8e-07 0.07 0.09 0.09 0.08 9.5e-06 4.6e-07 7.2e-07 2.0e-06
9 OFC gene expression ENSRNOG00000053923 0.23 0.14 1.6e-03 0.1 0.05 0.05 0.07 2.7e-03 2.6e-02 2.1e-02 9.6e-03
10 PL gene expression ENSRNOG00000053923 0.11 0.06 2.0e-06 0.05 0.07 0.06 0.08 1.1e-04 9.9e-06 3.5e-05 1.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.30.93.3-0.00.6-0.4-1.40.0-1.0-1.20.6-1.8-0.6
BMI without tail1.22.68.21.00.5-1.6-1.8-1.4-0.9-2.90.1-2.7-0.9
Body weight0.52.06.01.20.4-1.6-1.4-1.2-0.6-2.4-0.0-2.4-0.4
Epididymis fat weight1.43.28.4-0.11.4-1.9-2.20.3-1.6-2.61.2-2.9-1.4
Glucose0.10.10.30.5-0.10.20.00.10.50.4-0.10.50.3
Heart weight0.91.31.90.9-1.31.01.3-1.21.10.8-1.41.11.2
Left kidney weight0.51.44.42.1-0.9-0.30.3-2.01.1-0.8-1.3-0.30.9
Right kidney weight0.30.93.01.7-0.6-0.50.2-1.40.9-0.8-0.9-0.30.7
Tail length1.13.49.13.0-0.9-1.6-0.2-3.01.2-2.4-1.7-1.20.8
Length with tail0.51.84.82.0-0.1-1.8-0.5-1.70.5-2.2-0.7-1.30.3
Length without tail0.10.31.1-0.60.5-0.0-0.31.0-0.40.30.7-0.0-0.2
Liver weight, left0.71.14.0-0.11.0-2.0-1.00.2-0.7-1.60.7-1.2-0.6
Liver weight, right2.64.39.3-0.62.1-3.0-2.20.8-1.8-2.81.7-2.7-1.5
Parametrial fat weight0.61.22.9-0.40.9-1.6-1.10.2-1.1-1.70.6-1.5-0.9
Retroperitoneal fat weight4.916.331.4-1.43.8-4.8-4.81.3-3.8-5.53.2-5.6-3.6
Intraocular pressure0.71.02.20.4-1.11.51.0-0.50.81.3-0.91.10.9
Extensor digitorum longus weight0.31.13.2-0.10.5-1.2-0.9-0.5-1.1-1.80.2-1.8-0.7
Soleus weight0.61.75.70.20.8-2.0-1.1-0.6-0.9-2.40.3-1.8-0.8
Tibialis anterior weight0.10.20.90.5-0.4-0.20.2-0.90.0-0.5-0.6-0.50.3
Tibia length1.64.68.31.4-2.42.92.1-1.61.92.4-2.12.02.2
Number of licking bursts4.75.67.1-2.22.6-2.2-2.42.0-2.7-2.02.5-2.5-2.4
Food consumed during 24 hour testing period3.34.07.51.8-1.81.22.3-1.42.61.7-1.82.72.0
Times rat made contact with spout0.60.71.9-0.20.9-1.4-0.8-0.0-0.5-1.40.6-0.7-0.8
Mean time between licks in bursts3.24.410.73.3-2.00.31.7-2.62.60.2-2.41.12.4
Mean num. licks in bursts3.64.35.72.1-2.31.82.0-2.12.41.4-2.32.12.1
Std. dev. time between licks in bursts0.60.72.41.5-0.5-0.50.3-1.30.9-0.6-0.9-0.00.6
Water consumed over 24 hours1.21.42.0-1.21.4-1.2-1.11.1-1.1-0.91.3-0.8-1.4
Indifference point 0 sec5.79.112.43.0-3.42.53.1-3.43.12.0-3.52.53.2
Indifference point AUC0.10.10.30.3-0.1-0.50.2-0.50.0-0.4-0.3-0.30.1
Indifference point function ln k1.82.54.31.0-1.62.11.6-0.81.61.9-1.41.91.6
Indifference point function log k1.82.54.31.0-1.62.11.6-0.81.61.9-1.41.91.6
Delay discounting total patch changes 0 sec4.77.610.22.7-3.12.32.9-3.12.91.9-3.22.33.0
Delay discounting total patch changes 12 sec1.01.33.61.4-1.30.41.0-1.91.0-0.1-1.50.31.0
Delay discounting total patch changes 18 sec1.51.93.91.9-1.50.61.2-2.01.50.2-1.80.71.4
Delay discounting total patch changes 24 sec0.40.51.51.2-0.70.30.3-0.60.90.1-0.80.30.8
Delay discounting total patch changes 6 sec1.42.13.10.9-1.81.41.8-1.51.21.2-1.71.21.5
Delay discounting time to switch 0 sec4.16.28.7-2.82.8-1.6-2.52.9-2.8-1.32.9-2.1-2.7
Delay discounting water rate 0 sec3.55.67.12.5-2.61.92.3-2.52.61.6-2.72.12.5
Delay discounting water rate 12 sec2.43.65.12.0-2.01.71.8-1.52.31.5-2.02.02.0
Delay discounting water rate 18 sec0.60.81.41.2-1.00.60.7-1.01.20.4-1.00.80.8
Delay discounting water rate 24 sec1.21.63.20.8-1.31.81.2-0.51.41.6-1.11.61.1
Delay discounting water rate 6 sec0.91.41.80.7-1.31.31.3-0.81.11.2-1.21.31.1
Locomotor activity0.81.32.51.6-1.10.81.0-1.21.60.5-1.31.11.0
Locomotor testing distance1.72.86.22.5-1.81.11.1-2.02.00.4-1.90.91.7
Locomotor testing rearing0.50.83.01.7-0.6-0.1-0.2-1.30.8-0.9-0.9-0.30.6
Light reinforcement 11.83.34.2-1.72.0-1.9-1.71.7-2.0-1.51.9-2.0-1.7
Light reinforcement 20.10.10.3-0.10.0-0.10.40.30.00.50.10.30.4
Reaction time number correct0.30.51.5-0.3-0.30.90.80.40.41.2-0.11.10.3
Reaction time mean minus median1.01.32.51.6-1.20.40.9-1.41.30.2-1.40.71.3
Reaction time mean minus median AUC1.51.92.61.6-1.50.81.4-1.31.60.8-1.61.21.6
Reaction time num false alarms2.73.75.3-1.72.0-1.8-1.91.4-2.3-1.81.9-2.3-2.0
Reaction time num false alarms AUC1.62.22.9-1.41.6-1.3-1.41.4-1.7-1.21.6-1.6-1.5
Reaction time trials correct on left0.30.51.5-0.3-0.30.90.80.40.41.2-0.11.10.3
Reaction time trials on left0.40.51.6-0.3-0.40.90.80.40.41.3-0.11.20.4
Reaction time mean0.20.31.10.00.5-1.0-0.50.2-0.3-0.80.3-0.6-0.3
Reaction time mean AUC0.40.51.4-0.30.8-1.2-0.70.7-0.6-0.80.7-0.7-0.5
Median of all reaction times0.50.71.5-0.50.9-1.2-0.80.7-0.8-0.80.8-0.8-0.7
Reaction time omissions0.10.10.40.10.1-0.4-0.20.1-0.3-0.30.1-0.60.2
Reaction time false alarm rate2.02.84.4-1.31.7-1.7-1.71.2-1.9-1.61.6-2.1-1.6
Reaction time premature initiation rate1.01.34.81.6-1.1-0.10.4-2.20.6-1.0-1.5-0.60.8
Reaction time premature initiations0.91.23.31.4-1.30.60.9-1.80.9-0.1-1.50.21.0
Std. dev. reaction times0.40.51.51.2-0.5-0.40.1-1.10.6-0.7-0.8-0.30.6
Reaction time trials completed0.40.51.6-0.3-0.40.90.80.40.41.3-0.11.20.4
Reaction time trials AUC0.30.41.3-0.1-0.40.80.70.30.51.1-0.21.10.4
Social response proportion0.60.71.3-0.51.0-1.1-0.80.6-0.7-0.90.9-0.7-0.8
Social responses1.31.73.0-0.61.2-1.7-1.40.4-1.2-1.71.0-1.7-1.3
Social time2.83.66.8-2.12.2-1.2-1.92.6-2.0-0.72.4-1.4-1.8
Conditioned locomotion0.00.10.2-0.2-0.10.30.20.10.10.40.00.4-0.0
Cocaine response after cond. corrected1.41.52.0-0.81.4-1.4-1.31.4-1.2-1.01.4-1.3-1.0
Cocaine response after cond. not corrected0.30.31.0-0.30.7-0.6-0.51.0-0.4-0.20.7-0.4-0.3
Cocaine response before conditioning1.41.72.90.7-1.31.31.6-0.91.31.5-1.21.71.2
Saline control response1.52.14.32.1-1.40.61.2-1.51.80.5-1.61.11.7
Condit. Reinf. active minus inactive responses5.26.59.83.1-2.91.82.4-3.02.61.3-3.01.43.0
Condit. Reinf. active-inactive response ratio0.80.81.21.1-1.11.10.7-1.00.80.7-1.00.31.0
Condit. Reinf. active responses7.210.017.14.1-3.51.73.0-3.83.31.3-3.81.73.8
Condit. Reinf. inactive responses4.65.711.63.4-2.40.62.2-2.72.90.6-2.81.62.8
Condit. Reinf. lever presses19.526.935.25.5-5.73.75.5-5.45.63.5-5.94.35.9
Condit. Reinf. lever reinforcers received8.211.518.74.3-3.82.03.2-4.03.61.6-4.02.04.0
Pavlov. Cond. lever latency20.227.735.6-5.55.8-4.1-5.55.6-5.6-3.85.9-4.4-6.0
Pavlov. Cond. magazine entry latency6.47.39.52.2-3.12.73.0-2.82.52.4-3.02.32.9
Pavlov. Cond. change in total contacts14.119.725.14.6-5.03.94.5-4.54.63.5-4.93.65.0
Pavlov. Cond. index score16.221.226.74.6-5.24.04.8-4.84.73.5-5.23.85.1
Pavlov. Cond. latency score15.219.324.24.2-4.93.94.7-4.54.53.5-4.93.74.9
Pavlov. Cond. lever contacts21.229.537.75.6-6.04.35.7-5.85.73.9-6.14.56.1
Pavlov. Cond. magazine entry number8.310.313.1-3.03.6-3.3-3.33.2-3.1-2.83.5-2.6-3.5
Pavlov. Cond. intertrial magazine entries0.50.72.30.50.6-1.5-0.8-0.1-0.2-1.50.2-0.9-0.4
Pavlov. Cond. lever-magazine prob. diff.15.119.524.64.5-4.93.84.6-4.64.53.3-5.03.65.0
Pavlov. Cond. response bias21.329.437.75.5-6.14.55.7-5.85.63.9-6.14.46.0
Conditioned reinforcement - actives3.03.04.61.1-1.72.01.8-1.11.81.9-1.62.11.8
Conditioned reinforcement - inactives0.20.30.8-0.50.7-0.8-0.30.9-0.2-0.20.60.1-0.3
Conditioned locomotion2.32.84.51.2-1.62.01.6-0.61.82.0-1.42.11.8
Intermittent access intake day 1-15 change2.72.74.01.1-1.61.62.0-0.91.71.8-1.52.01.7
Intermittent access intake escalation3.43.34.91.3-1.81.82.1-1.12.02.0-1.72.22.0
Intermittent access intake escalation 20.80.81.20.7-1.00.81.1-0.80.90.8-1.01.01.0
Intermitt. access day 1 inactive lever presses0.60.70.9-0.70.9-0.9-0.90.8-0.8-0.60.9-0.6-0.9
Intermitt. access day 15 inactive lever presses0.10.10.2-0.30.20.1-0.00.5-0.10.30.30.20.0
Intermitt. access escalation Index0.10.10.2-0.1-0.20.10.3-0.5-0.10.0-0.30.0-0.0
Intermittent access day 1 total infusions0.50.50.90.9-0.70.10.7-0.90.90.1-0.90.60.8
Intermittent access day 15 total infusions2.73.14.71.4-1.71.42.0-1.22.01.6-1.72.21.9
Intermittent access terminal intake (last 3 days)1.61.72.31.1-1.41.01.5-1.11.51.0-1.41.51.5
Intermittent access total infusions0.60.71.00.9-0.90.50.9-0.81.00.5-0.90.91.0
Intermittent access day 1 locomotion0.00.00.2-0.1-0.10.20.20.10.20.3-0.00.50.1
Intermittent access day 15 total locomotion1.81.92.71.3-1.41.31.3-0.81.61.3-1.31.61.6
Intermittent access total locomotion0.50.61.00.9-0.80.50.7-0.61.00.5-0.80.71.0
Intermittent access standard deviation0.10.10.20.4-0.2-0.00.1-0.20.5-0.1-0.20.40.3
Cocaine induced anxiety2.22.63.3-1.71.7-1.3-1.61.5-1.8-1.11.8-1.5-1.8
Post-drug Anxiety0.50.50.7-0.80.8-0.7-0.60.7-0.8-0.50.8-0.5-0.8
Baseline Anxiety2.62.73.51.6-1.71.21.9-1.51.91.2-1.81.71.8
Lifetime Intake0.91.01.51.0-1.00.71.1-0.91.20.7-1.11.11.1
Incentive Sensitization - Responses2.52.54.02.0-1.71.11.3-1.91.70.6-1.91.01.8
Incentive Sensitization - Breakpoint2.52.53.81.9-1.81.21.4-1.81.70.8-1.81.11.8
Progressive ratio test 1 active lever presses0.20.20.6-0.50.5-0.2-0.30.8-0.4-0.00.5-0.1-0.2
Progressive ratio test 1 breakpoint0.10.20.4-0.60.4-0.3-0.20.6-0.4-0.10.5-0.1-0.3
Progressive ratio test 1 inactive lever presses0.00.10.10.1-0.30.10.3-0.40.20.1-0.30.20.3
Progressive ratio test 2 active lever presses1.21.32.41.6-1.20.80.9-1.21.40.5-1.30.91.4
Progressive ratio test 2 breakpoint1.11.22.11.4-1.20.80.9-1.21.30.5-1.30.81.3
Progressive ratio test 2 inactive lever presses0.50.61.01.0-0.80.60.5-0.80.90.4-0.90.60.9
Total sessions with >9 infusions2.62.83.41.3-1.91.81.8-1.51.71.5-1.81.71.8
Short access day 1 total inactive lever presses0.10.20.6-0.00.5-0.5-0.40.70.1-0.20.50.1-0.1
Short access day 10 total inactive lever presses0.10.10.3-0.50.4-0.1-0.30.5-0.4-0.10.4-0.1-0.4
Short access day 1 total infusions2.22.43.41.7-1.60.91.5-1.51.90.9-1.71.61.7
Short access day 10 total infusions0.40.50.80.9-0.70.40.6-0.90.80.1-0.80.50.7
Short access total infusions0.50.60.90.8-0.80.40.8-0.90.80.3-0.90.70.8
Short access day 1 locomotion3.53.76.01.0-1.92.32.1-0.91.92.3-1.72.52.0
Short access day 10 total locomotion0.30.30.40.6-0.60.50.3-0.50.60.3-0.50.40.7
Short access total locomotion0.20.20.50.1-0.40.60.5-0.20.40.6-0.40.70.5
Compulsive drug intake0.10.10.80.1-0.30.90.00.10.10.5-0.10.10.2
One hour access (0.3 mA shock)1.72.02.71.6-1.61.31.1-1.61.60.8-1.61.21.5
One hour access (shock baseline)1.41.62.41.3-1.30.81.2-1.21.50.8-1.41.41.4
Number of responses in last shaping day0.30.30.90.20.1-0.5-0.4-0.8-0.4-0.9-0.1-0.9-0.3
Context. condit. distance diff. score2.53.16.00.9-2.12.51.8-2.11.21.6-2.01.31.4
Locomotion velocity, session 10.30.31.5-0.20.40.3-0.11.20.30.70.60.7-0.0
Locomotion distance, session 10.81.12.10.8-0.91.50.9-0.21.11.4-0.61.21.1
Locomotion velocity, session 20.20.20.90.80.1-0.2-0.00.30.90.10.00.70.3
Locomotion distance, session 20.20.40.80.8-0.40.50.3-0.20.90.6-0.40.80.6
Locomotion velocity, session 30.40.51.70.5-0.71.30.3-0.40.70.9-0.50.70.4
Locomotion distance, session 31.01.12.50.5-1.11.60.9-0.50.91.5-0.81.10.9
Stereotopy head waving bouts, day 30.40.41.2-0.20.8-1.1-0.60.5-0.3-0.80.6-0.4-0.7
Stereotopy head waving duration, day 30.30.40.90.6-0.60.50.6-0.40.90.5-0.60.90.5
Locomotion velocity, session 70.20.30.5-0.70.40.1-0.60.3-0.7-0.10.6-0.6-0.7
Locomotion distance, session 70.10.10.4-0.10.2-0.1-0.60.0-0.4-0.40.2-0.6-0.3
Stereotopy head waving bouts, day 71.82.13.01.1-1.41.31.6-1.01.61.5-1.31.71.4
Stereotopy head waving duration, day 72.32.94.11.7-1.71.31.8-1.52.01.4-1.71.91.8
Locomotion velocity, session 81.82.23.50.9-1.61.11.9-1.61.51.2-1.71.71.3
Locomotion distance, session 81.92.84.51.3-1.82.11.6-1.61.71.6-1.71.61.5
Degree of sensitization distance0.90.92.80.10.7-1.5-0.9-0.2-0.7-1.70.3-1.3-0.5
Degree of sensitization stereotypy4.65.06.61.8-2.32.12.6-1.62.42.4-2.12.52.4
Condit. Reinf. active minus inactive responses0.30.30.90.40.0-0.4-0.5-0.7-0.3-1.0-0.1-1.0-0.3
Condit. Reinf. active-inactive response ratio0.40.41.80.6-0.5-0.20.2-1.30.0-0.8-0.8-0.60.1
Condit. Reinf. active responses0.30.40.9-0.00.4-0.6-0.8-0.1-0.5-0.90.3-1.0-0.6
Condit. Reinf. inactive responses0.20.30.5-0.30.6-0.3-0.70.7-0.3-0.20.7-0.4-0.5
Incentive salience index mean0.20.20.80.30.1-0.3-0.6-0.6-0.2-0.9-0.1-0.8-0.4
Condit. Reinf. lever presses0.00.00.10.10.1-0.1-0.3-0.20.1-0.30.0-0.0-0.3
Time in familiar zone, hab. session 10.20.20.6-0.40.4-0.8-0.10.2-0.4-0.50.3-0.3-0.4
Time in novel zone, hab. session 10.10.10.40.10.2-0.1-0.50.1-0.3-0.50.2-0.7-0.3
Total zone transitions, hab. session 10.40.51.3-0.1-0.61.00.9-0.10.51.1-0.51.10.5
Total locomotion distance, hab. session 11.42.03.8-0.71.4-1.5-1.60.5-1.5-1.81.2-2.0-1.5
Locomotion velocity, hab. session 10.81.22.5-0.51.0-1.1-1.30.2-1.1-1.40.9-1.6-1.1
Time in familiar zone, hab. session 20.70.72.30.9-1.00.20.9-1.50.7-0.1-1.20.40.7
Time in novel zone, hab. session 20.20.21.2-0.10.50.2-0.61.1-0.20.30.7-0.1-0.1
Total zone transitions, hab. session 21.82.44.10.8-1.62.01.8-1.01.32.0-1.41.61.6
Total locomotion distance, hab. session 20.50.61.9-0.20.5-0.9-0.7-0.3-0.9-1.10.4-1.4-0.5
Locomotion velocity, hab. session 20.60.82.2-0.20.7-1.1-0.8-0.2-0.9-1.30.5-1.5-0.6
Novel to familiar place preference ratio0.20.20.40.4-0.40.60.4-0.00.40.6-0.30.40.7
Novelty place preference0.10.10.30.5-0.20.50.20.10.40.5-0.10.30.5
Time in novel zone, NPP test0.30.30.50.6-0.40.70.4-0.10.60.6-0.30.40.7
Total zone transitions, NPP test0.30.51.30.0-0.50.80.80.10.51.1-0.30.90.6
Total locomotion distance, NPP test1.31.83.6-0.71.4-1.4-1.50.9-1.5-1.41.4-1.9-1.1
Locomotion velocity, NPP test1.82.64.5-0.91.7-1.6-1.81.3-1.7-1.51.7-2.1-1.4
Pavlov. Cond. lever latency0.70.91.7-1.10.9-0.4-0.91.3-1.2-0.21.1-1.0-0.8
Pavlov. Cond. magazine entry latency2.02.54.91.9-1.81.21.4-2.21.50.6-2.00.91.7
Pavlov. Cond. change in total contacts0.50.61.01.0-0.80.50.7-0.90.90.4-0.80.50.9
Pavlov. Cond. index score1.62.04.41.9-1.50.81.2-2.11.60.2-1.80.91.4
Pavlov. Cond. latency score1.62.14.41.8-1.60.81.2-2.11.60.3-1.80.91.4
Pavlov. Cond. lever contacts0.40.51.51.1-0.60.10.4-1.20.9-0.2-0.80.50.5
Pavlov. Cond. magazine entry number2.43.05.1-2.02.0-1.3-1.62.3-1.7-0.82.1-1.1-1.9
Pavlov. Cond. intertrial magazine entries2.02.43.7-1.21.8-1.2-1.91.9-1.3-0.91.9-1.1-1.7
Pavlov. Cond. lever-magazine prob. diff.1.21.63.41.6-1.30.61.0-1.81.40.2-1.50.81.2
Pavlov. Cond. response bias0.40.51.41.0-0.60.20.4-1.20.8-0.2-0.80.30.5
Bone: apparent density0.10.20.5-0.70.3-0.5-0.0-0.0-0.6-0.50.1-0.3-0.5
Bone surface0.91.63.71.2-1.40.51.4-1.91.10.2-1.70.81.3
Bone volume0.30.51.80.8-0.80.00.6-1.30.6-0.3-1.00.10.6
Bone: connectivity density0.10.20.7-0.4-0.50.30.8-0.60.10.3-0.60.60.1
Bone: cortical apparent density1.21.62.9-0.91.4-1.7-1.11.3-1.0-1.31.2-0.9-1.3
Bone: cortical area0.30.51.80.8-0.80.20.3-1.30.2-0.4-1.0-0.60.7
Bone: cortical porosity1.71.93.01.1-1.31.61.3-0.81.61.6-1.11.71.4
Bone: cortical porosity1.21.32.60.9-1.01.41.0-0.51.41.5-0.81.61.1
Bone: cortical thickness0.20.40.9-0.60.4-0.3-0.60.3-0.9-0.50.5-1.0-0.4
Bone: cortical thickness0.20.20.60.3-0.50.80.3-0.10.20.6-0.30.10.6
Bone: cortical tissue density1.21.52.9-0.91.5-1.7-1.11.3-1.0-1.31.3-0.9-1.3
Bone: elastic displacement1.41.62.7-1.61.3-0.5-1.11.5-1.6-0.61.4-1.1-1.4
Bone: elastic work1.31.74.0-2.01.3-0.4-0.91.6-1.6-0.21.5-0.8-1.4
Bone: endosteal estimation0.71.54.21.9-1.20.10.7-2.01.2-0.5-1.50.11.1
Bone: endosteal perimeter1.42.85.42.3-1.80.61.5-2.31.90.2-2.10.91.8
Bone: final force0.10.10.5-0.1-0.40.00.7-0.6-0.10.1-0.50.00.4
Bone: final moment0.10.20.70.1-0.60.00.8-0.80.10.1-0.70.10.5
Bone: marrow area0.61.23.71.7-1.0-0.00.6-1.91.0-0.6-1.4-0.01.0
Bone: maximum diameter1.73.26.62.2-2.01.01.6-2.61.60.4-2.30.62.0
Bone: maximum force0.20.41.20.0-0.80.31.1-1.00.20.3-0.80.30.6
Bone: maximum moment0.30.61.50.3-0.90.31.2-1.20.40.3-1.00.40.7
Bone: minimum diameter0.40.82.40.9-0.1-1.0-0.3-1.3-0.1-1.5-0.5-1.20.1
Bone: periosteal estimation0.81.64.31.8-1.30.30.8-2.11.0-0.4-1.6-0.11.3
Bone: periosteal perimeter1.21.94.21.9-1.50.41.2-2.01.4-0.0-1.80.61.4
Bone: post-yield work0.50.71.80.3-0.90.41.2-1.30.70.4-1.10.90.6
Bone: stiffness0.10.10.4-0.40.0-0.60.5-0.4-0.4-0.2-0.1-0.20.1
Bone: tissue strength0.50.41.3-1.2-0.11.00.50.4-0.41.10.20.5-0.1
Bone: trabecular number0.91.43.3-1.81.1-0.7-0.80.9-1.7-0.71.1-1.0-1.5
Bone: trabecular spacing1.41.82.81.5-1.31.41.1-0.71.71.4-1.11.51.6
Bone: trabecular thickness0.60.71.5-0.40.7-1.1-0.80.1-0.8-1.20.5-1.2-0.8
Bone: trabecular tissue density1.01.43.2-0.41.3-1.8-1.20.9-0.9-1.51.0-1.4-0.9
Breakpoint value in progressive ratio session0.10.20.4-0.60.40.0-0.30.6-0.40.10.5-0.1-0.4
Distance traveled before self-admin0.30.40.5-0.70.7-0.7-0.50.5-0.7-0.50.6-0.5-0.6
Distance traveled after self-admin0.80.92.3-1.31.0-0.2-0.71.5-0.90.21.2-0.1-0.9
Delta time in closed arm before/after self-admin1.21.23.1-0.20.9-1.7-1.0-0.2-0.9-1.80.5-1.4-1.0
Delta time in open arm before/after self-admin2.22.12.91.6-1.60.81.4-1.71.60.7-1.71.21.6
Diff in mean of infusions in LGA sessions3.64.15.0-1.92.2-1.7-2.21.8-2.2-1.62.2-2.0-2.2
Extinction: sum of active levers before priming0.20.20.50.20.5-0.7-0.60.4-0.0-0.50.4-0.3-0.2
Active lever presses in extinction session 64.94.77.71.4-2.12.82.1-1.02.32.6-1.82.72.2
Delta distance traveled before/after self-admin0.20.20.6-0.1-0.30.70.40.20.30.8-0.10.70.3
Delta ambulatory time before/after self-admin0.40.41.4-0.3-0.31.00.50.30.31.2-0.10.90.4
Time in closed arm before self-admin1.61.83.70.5-1.31.81.5-0.31.21.9-1.01.81.3
Time in closed arm after self-admin0.30.31.2-0.90.5-0.2-0.01.1-0.30.40.70.3-0.4
Time in open arm before self-admin3.13.34.1-1.72.0-1.6-1.91.7-2.0-1.52.0-1.8-2.0
Time in open arm after self-admin0.30.31.30.7-0.3-0.4-0.1-1.20.1-0.9-0.6-0.50.1
Sum of active levers in priming session hrs 5-60.00.00.10.20.2-0.1-0.30.30.1-0.00.20.00.0
Time to tail flick, vehicle, before self-admin0.60.61.0-0.60.6-0.9-0.80.1-0.9-0.90.5-1.0-0.9
Time to tail flick, vehicle, after self-admin2.12.22.91.1-1.71.61.7-1.41.41.4-1.61.51.5
Time to tail flick, test, before self-admin0.10.10.40.4-0.2-0.20.0-0.60.1-0.4-0.3-0.30.1
Time to tail flick, test, after self-admin0.20.20.90.9-0.1-0.3-0.2-0.40.5-0.5-0.3-0.20.3
Delta time to tail flick, vehicle, before/after SA4.14.05.41.3-2.02.32.2-1.12.02.2-1.82.32.1
Delta time to tail flick, test, before/after SA0.10.10.5-0.20.4-0.0-0.30.7-0.10.10.40.1-0.2
Ambulatory time before self-admin0.40.40.8-0.80.7-0.5-0.50.9-0.7-0.20.8-0.3-0.7
Ambulatory time after self-admin0.80.93.1-1.30.90.1-0.51.8-0.60.61.20.3-0.7
Total heroin consumption0.10.10.20.2-0.30.40.5-0.30.30.4-0.30.30.4
Area under the delay curve0.10.10.20.2-0.20.10.4-0.10.30.3-0.20.40.2
Delay disc. indifference point, 0s delay0.50.51.11.1-0.80.50.6-0.50.90.5-0.80.60.9
Delay disc. indifference point, 16s delay0.10.10.3-0.30.10.20.20.30.10.40.20.6-0.1
Delay disc. indifference point, 2s delay1.31.41.91.2-1.21.01.2-1.01.41.0-1.21.21.3
Delay disc. indifference point, 24s delay0.90.91.2-1.01.1-1.1-0.80.8-1.0-0.71.0-0.7-1.1
Delay disc. indifference point, 4s delay0.40.41.71.3-0.40.10.2-0.31.00.2-0.50.40.8
Delay disc. indifference point, 8s delay0.40.40.80.3-0.70.60.9-0.80.50.6-0.70.70.5
Delay discount exponential model param0.10.10.2-0.10.1-0.0-0.30.0-0.3-0.30.1-0.5-0.2
Delay discount hyperbolic model param0.10.20.3-0.40.3-0.1-0.40.2-0.6-0.40.3-0.6-0.4
Fecal boli incidents, locomotor time 11.01.11.50.7-1.11.11.2-0.61.01.1-1.01.21.1
Change in fecal boli incidents, locomotor task1.00.91.5-1.11.2-0.8-1.01.2-0.9-0.51.2-0.5-1.1
Time >=10cm from walls, locomotor time 12.42.43.70.9-1.71.91.6-1.11.51.7-1.51.81.4
Bouts of movement, locomotor time 10.10.10.30.5-0.20.30.20.10.50.4-0.20.50.3
Total resting periods, locomotor time 10.10.10.30.1-0.00.40.10.50.30.50.10.50.1
Rest time, locomotor task time 10.30.31.3-0.30.50.0-0.21.10.10.50.70.6-0.2
Distance moved, locomotor task time 10.40.51.90.8-0.5-0.30.1-1.40.1-0.9-0.7-0.80.3
Vertical activity count, locomotor time 10.70.73.00.8-1.00.30.6-1.70.3-0.3-1.1-0.40.8
Time >=10cm from walls, locomotor time 20.90.91.71.3-1.00.90.7-0.81.20.7-1.00.81.1
Bouts of movement, locomotor time 20.50.51.31.1-0.60.30.5-0.51.00.3-0.70.70.7
Total resting periods, locomotor time 20.20.30.70.8-0.40.30.3-0.20.80.3-0.40.60.5
Rest time, locomotor task time 21.92.23.0-1.71.7-1.3-1.31.7-1.6-0.91.7-1.1-1.6
Distance moved, locomotor task time 22.22.54.72.2-1.81.21.2-2.01.70.6-1.90.81.8
Vertical activity count, locomotor time 21.11.23.61.5-1.20.40.6-1.90.9-0.2-1.4-0.11.1
Weight adjusted by age0.40.51.31.2-0.3-0.3-0.3-1.10.3-0.9-0.5-0.70.3
Seeking ratio, delayed vs. immediate footshock2.12.43.2-1.51.7-1.0-1.61.8-1.6-0.91.8-1.4-1.7
Locomotion in novel chamber1.31.62.30.9-1.31.51.3-0.91.31.4-1.21.41.4
Locomotion in novel chamber post-restriction4.95.98.71.7-2.52.92.4-1.42.62.7-2.22.92.5
Progressive ratio0.20.20.5-0.1-0.40.60.6-0.10.20.7-0.20.40.4
Food seeking constrained by brief footshock1.41.73.41.9-1.30.41.2-1.41.60.4-1.51.01.6
Seeking ratio, punishment vs. effort0.50.72.11.4-0.7-0.40.4-1.11.0-0.4-0.90.30.8
Run reversals in cocaine runway, females2.12.16.30.10.9-2.2-1.3-0.6-1.0-2.50.4-2.1-1.1
Run reversals in cocaine runway, males0.10.10.2-0.1-0.1-0.20.40.10.20.2-0.10.50.2
Latency to leave start box in cocaine runway1.81.92.7-1.41.6-1.2-1.31.5-1.5-0.91.6-1.2-1.5
Latency to leave start box in cocaine runway, F1.51.72.1-1.11.4-1.3-1.31.1-1.4-1.11.4-1.4-1.3
Latency to leave start box in cocaine runway, M0.20.20.8-0.90.30.1-0.00.6-0.40.30.50.2-0.4
Cd content in liver1.31.42.6-0.91.1-1.2-1.30.1-1.4-1.41.0-1.6-1.4
Co content in liver0.40.41.41.2-0.5-0.1-0.1-1.10.7-0.6-0.7-0.10.4
Cu content in liver0.30.41.61.3-0.3-0.3-0.1-0.80.9-0.4-0.50.30.6
Fe content in liver0.00.00.1-0.10.1-0.2-0.2-0.1-0.2-0.20.1-0.30.0
K content in liver0.30.30.6-0.40.6-0.8-0.50.3-0.3-0.60.5-0.2-0.7
Mg content in liver0.10.20.20.4-0.40.40.3-0.40.50.3-0.40.50.4
Mn content in liver1.01.23.6-1.51.1-0.2-0.61.9-1.00.21.3-0.1-1.0
Na content in liver0.91.02.40.3-0.81.01.20.01.01.3-0.71.60.9
Rb content in liver0.50.61.61.1-0.80.30.5-1.30.9-0.1-1.00.50.6
Se content in liver4.04.88.1-2.52.5-1.6-2.02.8-2.2-1.02.7-1.4-2.4
Sr content in liver0.10.10.3-0.1-0.10.5-0.00.30.00.40.10.20.1
Zn content in liver5.05.57.62.6-2.61.92.2-2.82.61.5-2.61.92.5