Hub : Genes

Tesk1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000053729 0.61 0.22 0.0e+00 0.37 0.4 0.38 0.39 1.4e-20 1.2e-22 7.9e-22 3.1e-22
2 Brain gene expression ENSRNOG00000053729 0.29 0.11 0.0e+00 0.34 0.36 0.36 0.35 1.3e-32 9.6e-35 2.8e-34 4.7e-34
3 Brain mRNA stability ENSRNOG00000053729 0.08 0.05 2.1e-08 0.09 0.09 0.09 0.08 2.3e-08 1.7e-08 1.3e-08 4.5e-08
4 Eye gene expression ENSRNOG00000053729 0.28 0.18 6.6e-03 0.09 0.07 0.1 0.09 1.5e-02 2.9e-02 1.2e-02 1.6e-02
5 IL gene expression ENSRNOG00000053729 0.28 0.13 6.1e-07 0.23 0.18 0.23 0.23 2.8e-06 5.0e-05 3.1e-06 2.3e-06
6 LHb gene expression ENSRNOG00000053729 0.46 0.21 5.9e-05 0.13 0.04 0.12 0.13 4.6e-04 3.8e-02 9.1e-04 5.7e-04
7 LHb mRNA stability ENSRNOG00000053729 0.14 0.09 1.3e-03 0.07 0.04 0.06 0.05 1.1e-02 3.8e-02 1.6e-02 3.0e-02
8 Liver gene expression ENSRNOG00000053729 0.02 0.02 4.7e-03 0.01 0.01 0.01 0.01 6.9e-03 7.0e-03 2.0e-02 1.7e-02
9 NAcc gene expression ENSRNOG00000053729 0.32 0.14 0.0e+00 0.24 0.24 0.24 0.25 1.0e-17 1.4e-17 8.1e-18 2.1e-18
10 NAcc mRNA stability ENSRNOG00000053729 0.08 0.05 3.2e-07 0.09 0.09 0.09 0.09 3.4e-07 2.3e-07 1.9e-07 2.3e-07
11 OFC gene expression ENSRNOG00000053729 0.24 0.12 2.8e-05 0.14 0.16 0.16 0.06 2.6e-04 1.7e-04 1.2e-04 1.6e-02
12 PL gene expression ENSRNOG00000053729 0.41 0.15 0.0e+00 0.34 0.35 0.36 0.36 1.6e-26 1.5e-27 7.6e-29 2.4e-28
13 PL mRNA stability ENSRNOG00000053729 0.07 0.05 4.3e-06 0.06 0.07 0.06 0.06 3.1e-05 5.8e-06 2.2e-05 1.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail3.110.112.23.33.23.13.43.03.13.03.53.23.23.23.03.0
BMI without tail5.812.216.03.43.54.03.53.13.63.43.53.63.82.53.33.9
Body weight3.514.917.73.93.94.23.93.53.93.83.93.94.13.33.64.2
Epididymis fat weight0.30.81.40.80.91.20.30.71.00.90.31.11.20.50.81.2
Glucose1.01.62.31.21.31.51.21.11.21.31.21.31.41.01.21.5
Heart weight0.50.71.30.60.81.10.90.50.80.90.70.80.90.40.71.1
Left kidney weight0.20.71.60.60.81.20.80.40.80.80.80.80.90.30.61.3
Right kidney weight0.00.10.4-0.4-0.10.2-0.1-0.4-0.0-0.0-0.0-0.00.0-0.6-0.20.2
Tail length2.26.59.92.32.63.12.22.32.72.62.22.72.91.42.53.1
Length with tail0.51.73.71.11.31.70.91.11.41.40.71.41.50.61.21.9
Length without tail0.51.21.4-1.0-1.1-1.2-1.0-1.0-1.1-1.1-1.1-1.2-1.2-0.7-1.2-1.0
Liver weight, left0.40.61.10.60.70.9-0.20.81.00.7-0.51.11.00.10.90.9
Liver weight, right0.20.31.1-0.5-0.5-0.4-1.0-0.4-0.4-0.4-1.1-0.4-0.4-0.8-0.4-0.3
Parametrial fat weight0.10.20.50.30.30.70.30.10.60.20.10.70.7-0.20.40.6
Retroperitoneal fat weight0.00.10.3-0.4-0.4-0.5-0.4-0.3-0.2-0.3-0.3-0.1-0.2-0.1-0.3-0.5
Intraocular pressure1.52.23.81.51.51.81.51.21.41.41.41.41.50.91.32.0
Extensor digitorum longus weight4.417.822.14.14.34.74.33.94.34.34.04.24.43.54.04.7
Soleus weight0.61.75.2-1.5-1.2-0.4-1.5-1.3-0.9-1.1-1.8-1.0-0.8-2.3-1.3-0.1
Tibialis anterior weight5.719.728.54.34.55.34.34.04.64.43.84.64.83.14.25.3
Tibia length0.30.73.2-0.8-0.7-0.1-1.1-0.6-0.4-0.8-1.5-0.4-0.4-1.8-0.60.0
Number of licking bursts5.46.47.32.62.62.62.42.52.72.52.22.72.62.32.52.5
Food consumed during 24 hour testing period0.50.61.20.70.81.10.60.71.00.70.41.00.90.30.81.1
Times rat made contact with spout0.70.81.21.00.80.71.00.80.90.61.10.90.81.10.90.6
Mean time between licks in bursts0.60.82.5-0.8-0.8-0.8-1.4-0.4-0.6-0.7-1.6-0.7-0.7-1.1-0.5-0.8
Mean num. licks in bursts2.22.63.3-1.6-1.6-1.8-1.5-1.5-1.7-1.7-1.3-1.7-1.7-1.2-1.6-1.8
Std. dev. time between licks in bursts0.40.50.7-0.7-0.7-0.8-0.8-0.4-0.7-0.6-0.8-0.7-0.8-0.6-0.5-0.7
Water consumed over 24 hours1.01.11.51.11.01.11.20.91.10.81.21.11.11.11.01.0
Indifference point 0 sec0.20.30.9-0.4-0.20.40.3-1.0-0.4-0.00.6-0.5-0.2-0.6-0.80.7
Indifference point AUC7.68.911.82.93.13.33.12.82.83.22.72.83.02.52.93.4
Indifference point function ln k2.73.84.5-2.0-2.0-2.1-2.1-1.9-1.7-2.0-1.8-1.8-2.0-1.6-2.0-2.1
Indifference point function log k2.73.84.5-2.0-2.0-2.1-2.1-1.9-1.7-2.0-1.8-1.8-2.0-1.6-2.0-2.1
Delay discounting total patch changes 0 sec0.20.31.10.10.30.80.7-0.50.10.41.0-0.00.2-0.2-0.31.0
Delay discounting total patch changes 12 sec2.43.14.31.81.81.92.01.51.61.82.11.61.61.71.51.9
Delay discounting total patch changes 18 sec0.50.61.20.70.91.00.80.60.71.00.80.60.70.50.71.1
Delay discounting total patch changes 24 sec1.92.43.91.51.61.81.91.21.31.61.91.21.41.21.32.0
Delay discounting total patch changes 6 sec1.72.65.01.41.62.02.10.91.21.72.21.21.41.11.02.2
Delay discounting time to switch 0 sec2.23.35.5-1.7-1.9-2.3-2.0-1.4-1.6-1.9-2.0-1.6-1.8-1.4-1.5-2.4
Delay discounting water rate 0 sec1.22.03.81.31.31.91.80.71.11.22.01.11.41.00.91.8
Delay discounting water rate 12 sec0.00.00.1-0.1-0.20.2-0.2-0.3-0.1-0.3-0.2-0.10.0-0.3-0.20.1
Delay discounting water rate 18 sec0.60.81.41.00.80.81.10.80.70.61.20.80.71.20.80.7
Delay discounting water rate 24 sec0.30.31.00.70.50.30.70.60.30.21.00.40.41.00.50.0
Delay discounting water rate 6 sec0.50.71.20.90.81.10.70.81.00.40.71.01.00.40.81.0
Locomotor activity0.00.00.0-0.00.10.20.2-0.00.20.00.00.20.10.10.10.1
Locomotor testing distance0.20.30.9-0.7-0.5-0.2-0.6-0.7-0.4-0.5-0.9-0.4-0.4-0.9-0.6-0.1
Locomotor testing rearing0.30.51.10.60.71.00.50.60.90.70.20.80.80.20.71.1
Light reinforcement 10.30.51.7-0.20.11.1-0.3-0.50.50.0-0.60.50.6-1.3-0.21.2
Light reinforcement 20.70.94.1-1.0-0.70.2-1.0-1.1-0.6-0.7-1.2-0.6-0.4-2.0-0.90.5
Reaction time number correct0.00.00.10.00.10.30.3-0.1-0.10.00.2-0.10.0-0.1-0.00.3
Reaction time mean minus median1.82.33.91.61.50.91.32.01.71.61.11.61.42.01.80.7
Reaction time mean minus median AUC2.32.94.41.81.81.31.62.11.81.91.31.71.72.02.01.2
Reaction time num false alarms0.10.20.50.30.40.10.60.60.30.50.70.20.10.60.40.1
Reaction time num false alarms AUC0.40.61.20.60.80.71.10.80.70.81.10.60.50.70.70.7
Reaction time trials correct on left0.00.00.10.00.10.30.3-0.1-0.10.00.2-0.10.0-0.1-0.00.3
Reaction time trials on left0.00.00.1-0.1-0.00.20.2-0.2-0.2-0.10.2-0.1-0.1-0.2-0.10.2
Reaction time mean0.30.41.6-0.4-0.5-1.1-0.90.1-0.2-0.5-0.8-0.3-0.50.0-0.1-1.3
Reaction time mean AUC0.40.51.9-0.4-0.6-1.2-0.90.1-0.3-0.6-0.8-0.4-0.60.0-0.1-1.4
Median of all reaction times1.52.14.1-1.3-1.5-1.8-1.8-0.9-1.1-1.5-1.6-1.2-1.4-1.0-1.0-2.0
Reaction time omissions1.11.52.2-1.3-1.3-1.5-1.4-1.0-1.0-1.1-1.5-1.0-1.1-1.0-1.1-1.5
Reaction time false alarm rate0.00.10.20.10.2-0.10.40.30.20.30.40.1-0.10.40.2-0.1
Reaction time premature initiation rate1.31.73.5-1.1-1.4-1.8-1.4-1.2-1.1-1.4-1.2-1.1-1.2-0.5-1.2-1.9
Reaction time premature initiations0.81.22.2-0.9-1.2-1.4-1.0-1.1-1.0-1.2-0.9-1.0-1.0-0.5-1.1-1.5
Std. dev. reaction times0.40.61.50.70.60.00.31.20.90.70.20.80.71.21.0-0.2
Reaction time trials completed0.00.00.1-0.1-0.00.20.2-0.2-0.2-0.10.2-0.1-0.1-0.2-0.10.2
Reaction time trials AUC0.00.00.1-0.00.00.20.2-0.1-0.2-0.00.2-0.1-0.1-0.1-0.10.2
Social response proportion1.61.73.4-1.2-1.3-1.5-1.7-0.8-1.1-1.4-1.8-1.0-1.1-1.2-0.9-1.6
Social responses0.60.81.30.80.91.00.70.91.00.90.51.11.10.50.91.0
Social time0.30.42.0-0.7-0.5-0.4-1.1-0.3-0.2-0.4-1.4-0.1-0.2-1.0-0.2-0.4
Conditioned locomotion0.30.30.7-0.6-0.6-0.3-0.3-0.8-0.6-0.6-0.2-0.6-0.5-0.7-0.8-0.2
Cocaine response after cond. corrected3.33.75.4-2.0-1.9-1.6-1.9-2.1-1.9-2.0-1.8-1.9-1.9-2.3-2.0-1.4
Cocaine response after cond. not corrected3.13.56.2-2.0-1.9-1.4-2.0-2.0-1.7-1.8-2.1-1.7-1.7-2.5-1.9-1.2
Cocaine response before conditioning0.81.01.41.01.01.10.71.11.11.00.41.21.10.71.11.1
Saline control response0.30.41.20.40.51.10.30.20.70.40.10.80.8-0.20.41.1
Condit. Reinf. active minus inactive responses0.81.01.21.11.11.01.11.01.01.01.11.00.91.01.11.0
Condit. Reinf. active-inactive response ratio0.30.30.60.60.60.40.70.60.40.50.80.40.40.70.60.4
Condit. Reinf. active responses2.43.33.91.81.92.01.81.71.91.91.61.81.81.51.82.0
Condit. Reinf. inactive responses3.54.34.92.12.12.12.02.12.22.21.72.22.11.92.12.1
Condit. Reinf. lever presses3.24.55.02.22.22.02.12.22.12.21.92.12.12.22.21.9
Condit. Reinf. lever reinforcers received2.83.94.51.92.12.12.01.92.02.11.81.92.01.72.02.1
Pavlov. Cond. lever latency3.75.05.8-2.3-2.3-2.1-2.1-2.4-2.3-2.4-1.9-2.3-2.3-2.3-2.4-2.0
Pavlov. Cond. magazine entry latency0.30.30.9-0.6-0.5-0.7-0.8-0.3-0.4-0.4-1.0-0.4-0.5-0.5-0.3-0.7
Pavlov. Cond. change in total contacts1.62.23.41.61.51.11.21.81.61.61.01.51.51.71.81.0
Pavlov. Cond. index score0.50.71.20.90.80.60.61.10.90.90.40.80.81.01.00.4
Pavlov. Cond. latency score0.81.01.61.11.00.70.91.31.01.10.81.01.01.31.20.6
Pavlov. Cond. lever contacts1.82.53.11.61.71.51.51.71.61.81.31.61.61.61.71.5
Pavlov. Cond. magazine entry number0.30.30.8-0.6-0.6-0.2-0.3-0.9-0.6-0.6-0.3-0.6-0.5-0.9-0.8-0.1
Pavlov. Cond. intertrial magazine entries0.40.50.90.70.70.80.90.50.60.60.90.60.60.60.60.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.20.90.80.50.61.10.90.90.40.90.81.01.10.4
Pavlov. Cond. response bias0.91.21.71.11.10.90.91.31.11.20.71.11.11.21.30.9
Conditioned reinforcement - actives0.30.31.10.50.50.31.00.40.00.51.00.00.20.70.30.3
Conditioned reinforcement - inactives0.10.10.2-0.3-0.3-0.30.1-0.5-0.4-0.20.1-0.4-0.4-0.1-0.4-0.3
Conditioned locomotion0.40.51.90.60.60.51.20.30.30.41.40.30.30.80.40.6
Intermittent access intake day 1-15 change1.51.52.11.31.20.91.01.31.41.21.01.51.21.41.30.8
Intermittent access intake escalation2.02.02.71.51.41.21.21.51.61.31.31.61.51.61.51.1
Intermittent access intake escalation 22.72.73.51.81.61.31.61.81.81.41.61.81.71.91.81.1
Intermitt. access day 1 inactive lever presses0.70.81.10.90.91.01.00.61.00.81.01.00.90.80.70.9
Intermitt. access day 15 inactive lever presses0.00.00.2-0.2-0.10.00.0-0.40.10.1-0.10.20.1-0.1-0.40.1
Intermitt. access escalation Index0.60.51.20.70.71.00.10.50.90.50.10.91.00.10.61.1
Intermittent access day 1 total infusions1.01.12.2-1.1-1.0-0.8-0.2-1.4-1.5-0.9-0.1-1.5-1.2-0.8-1.4-0.7
Intermittent access day 15 total infusions0.60.61.60.70.80.71.20.50.50.81.30.50.51.00.50.7
Intermittent access terminal intake (last 3 days)0.70.82.30.80.80.81.40.50.50.81.50.50.61.00.60.8
Intermittent access total infusions0.70.72.50.70.80.81.50.30.40.81.60.30.51.00.40.9
Intermittent access day 1 locomotion1.41.43.0-1.3-1.1-1.0-0.1-1.4-1.7-1.00.1-1.7-1.5-0.8-1.4-1.0
Intermittent access day 15 total locomotion0.80.81.4-0.9-0.8-0.90.0-1.1-1.2-0.90.2-1.2-1.1-0.3-1.1-0.9
Intermittent access total locomotion0.40.40.8-0.5-0.5-0.70.5-0.7-0.9-0.50.8-0.9-0.80.2-0.7-0.7
Intermittent access standard deviation0.60.61.00.70.70.61.00.60.80.90.70.90.81.00.70.6
Cocaine induced anxiety1.51.72.3-1.2-1.3-1.3-1.5-1.2-1.2-1.5-1.5-1.2-1.2-1.3-1.2-1.3
Post-drug Anxiety0.20.20.40.40.30.5-0.40.40.60.3-0.60.60.6-0.20.50.6
Baseline Anxiety2.22.32.91.51.61.51.31.71.51.71.41.61.51.41.71.4
Lifetime Intake0.40.41.80.30.50.71.3-0.20.00.51.4-0.00.20.4-0.00.8
Incentive Sensitization - Responses0.20.20.4-0.4-0.4-0.2-0.3-0.6-0.4-0.4-0.1-0.4-0.4-0.5-0.6-0.2
Incentive Sensitization - Breakpoint0.20.20.5-0.5-0.5-0.4-0.4-0.7-0.5-0.5-0.2-0.5-0.5-0.5-0.7-0.3
Progressive ratio test 1 active lever presses0.20.21.0-0.1-0.00.20.8-0.7-0.4-0.11.0-0.4-0.30.1-0.50.3
Progressive ratio test 1 breakpoint0.20.21.30.00.10.41.0-0.5-0.20.11.1-0.2-0.10.2-0.30.4
Progressive ratio test 1 inactive lever presses0.20.20.6-0.3-0.20.40.3-0.8-0.2-0.30.3-0.2-0.2-0.6-0.60.5
Progressive ratio test 2 active lever presses0.40.41.1-0.7-0.5-0.30.1-1.0-0.9-0.40.2-0.9-0.8-0.5-0.9-0.2
Progressive ratio test 2 breakpoint0.60.71.5-0.9-0.7-0.5-0.0-1.2-1.1-0.60.1-1.1-1.0-0.6-1.1-0.4
Progressive ratio test 2 inactive lever presses0.10.10.70.20.30.30.8-0.00.10.30.70.1-0.00.30.00.4
Total sessions with >9 infusions0.60.71.7-0.9-0.7-0.30.1-1.3-1.0-0.70.1-1.0-0.8-0.9-1.2-0.1
Short access day 1 total inactive lever presses1.41.53.41.11.11.51.60.61.20.91.81.21.20.80.81.5
Short access day 10 total inactive lever presses0.30.30.70.60.40.50.10.40.80.40.00.80.80.40.50.5
Short access day 1 total infusions0.30.31.10.10.30.80.9-0.50.10.31.10.10.3-0.2-0.20.9
Short access day 10 total infusions0.20.21.00.00.10.60.8-0.4-0.20.11.0-0.20.0-0.1-0.30.6
Short access total infusions0.30.31.0-0.5-0.30.10.4-1.0-0.6-0.30.6-0.7-0.5-0.6-0.80.3
Short access day 1 locomotion0.50.51.2-0.8-0.6-0.40.1-1.1-0.8-0.60.3-0.9-0.8-0.8-0.9-0.4
Short access day 10 total locomotion0.30.40.8-0.5-0.5-0.80.0-0.4-0.8-0.40.2-0.8-0.8-0.1-0.5-0.9
Short access total locomotion0.10.10.3-0.3-0.20.10.4-0.5-0.5-0.30.6-0.5-0.4-0.4-0.40.1
Compulsive drug intake0.20.20.50.40.60.50.30.60.20.70.30.20.30.50.50.6
One hour access (0.3 mA shock)0.20.20.80.30.50.50.90.1-0.20.50.8-0.2-0.10.40.10.7
One hour access (shock baseline)0.20.20.90.10.20.40.9-0.3-0.10.20.9-0.1-0.00.2-0.20.5
Number of responses in last shaping day0.50.51.9-0.8-0.60.0-0.4-1.2-0.3-0.5-0.6-0.4-0.3-1.4-0.90.2
Context. condit. distance diff. score0.00.00.1-0.1-0.2-0.3-0.0-0.2-0.3-0.20.1-0.2-0.20.1-0.2-0.4
Locomotion velocity, session 10.50.52.5-0.8-0.50.4-0.4-1.2-0.4-0.4-0.5-0.4-0.1-1.6-0.90.6
Locomotion distance, session 10.10.10.6-0.3-0.00.5-0.0-0.40.00.0-0.20.00.2-0.7-0.30.6
Locomotion velocity, session 23.03.53.91.91.91.82.01.91.82.01.91.81.91.81.81.8
Locomotion distance, session 21.01.53.21.01.21.70.81.01.41.30.51.41.50.21.11.8
Locomotion velocity, session 30.20.20.9-0.5-0.40.0-0.4-0.7-0.3-0.3-0.5-0.3-0.2-0.9-0.50.2
Locomotion distance, session 31.71.83.01.21.31.71.60.81.31.21.61.31.40.91.01.7
Stereotopy head waving bouts, day 30.70.92.1-1.0-0.9-0.5-1.2-1.1-0.8-0.8-1.3-0.7-0.6-1.4-1.0-0.3
Stereotopy head waving duration, day 30.81.01.7-1.1-1.0-0.8-1.2-1.0-0.9-0.9-1.3-0.9-0.8-1.2-1.0-0.7
Locomotion velocity, session 70.00.00.1-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.3
Locomotion distance, session 70.10.10.30.40.40.50.50.30.30.30.50.30.40.20.30.5
Stereotopy head waving bouts, day 71.82.12.91.41.41.71.51.11.51.41.51.51.51.11.21.7
Stereotopy head waving duration, day 70.30.40.80.50.60.80.40.40.70.60.30.70.80.20.50.9
Locomotion velocity, session 80.30.31.2-0.6-0.4-0.1-0.8-0.4-0.3-0.3-1.0-0.3-0.1-1.1-0.40.1
Locomotion distance, session 80.00.10.2-0.10.10.4-0.1-0.10.10.1-0.30.20.3-0.5-0.00.5
Degree of sensitization distance1.11.11.7-1.0-1.0-1.2-1.2-0.7-1.0-1.0-1.3-1.0-1.0-0.9-0.8-1.2
Degree of sensitization stereotypy1.31.52.01.21.21.31.41.01.21.11.41.21.21.11.01.3
Condit. Reinf. active minus inactive responses0.60.71.00.80.90.80.81.00.90.90.70.80.80.80.90.8
Condit. Reinf. active-inactive response ratio0.40.40.8-0.6-0.7-0.8-0.7-0.4-0.6-0.8-0.7-0.6-0.7-0.5-0.5-0.9
Condit. Reinf. active responses3.44.14.82.02.12.01.92.12.12.21.72.12.11.92.12.0
Condit. Reinf. inactive responses4.35.16.42.22.42.22.02.32.42.51.82.42.52.12.32.2
Incentive salience index mean4.35.26.42.22.42.42.32.22.32.42.02.32.41.92.22.5
Condit. Reinf. lever presses8.811.816.93.23.63.93.43.13.43.73.13.43.62.53.24.1
Time in familiar zone, hab. session 10.40.42.00.70.4-0.20.70.70.20.21.00.20.11.40.5-0.5
Time in novel zone, hab. session 14.64.48.1-2.3-2.1-1.6-2.5-2.2-1.8-1.8-2.7-1.8-1.8-2.8-2.1-1.3
Total zone transitions, hab. session 10.00.00.00.10.10.1-0.00.20.10.1-0.10.10.20.00.10.1
Total locomotion distance, hab. session 10.91.21.91.21.20.81.01.31.11.20.91.11.11.41.30.7
Locomotion velocity, hab. session 12.33.33.91.81.91.71.72.01.82.01.61.81.91.91.91.6
Time in familiar zone, hab. session 20.10.10.7-0.1-0.2-0.7-0.30.1-0.3-0.3-0.2-0.2-0.40.3-0.0-0.8
Time in novel zone, hab. session 22.72.74.0-1.8-1.7-1.3-1.6-1.9-1.6-1.7-1.5-1.6-1.6-2.0-1.8-1.1
Total zone transitions, hab. session 20.20.30.80.30.50.80.40.30.50.50.30.60.7-0.10.40.9
Total locomotion distance, hab. session 20.81.11.41.01.11.11.01.01.01.10.91.11.20.81.01.1
Locomotion velocity, hab. session 21.21.61.81.21.31.31.31.21.21.31.21.31.41.11.21.3
Novel to familiar place preference ratio5.05.25.7-2.4-2.3-2.2-2.3-2.4-2.4-2.3-2.2-2.4-2.3-2.4-2.4-2.0
Novelty place preference6.36.56.9-2.6-2.6-2.5-2.5-2.6-2.6-2.6-2.4-2.6-2.6-2.5-2.6-2.3
Time in novel zone, NPP test7.68.08.6-2.9-2.9-2.8-2.8-2.9-2.9-2.8-2.7-2.9-2.9-2.8-2.9-2.6
Total zone transitions, NPP test0.30.41.10.30.50.90.40.30.60.60.20.70.8-0.20.41.0
Total locomotion distance, NPP test1.21.73.11.11.31.61.40.91.21.41.21.31.50.71.01.8
Locomotion velocity, NPP test1.92.84.21.51.72.01.81.31.61.71.71.61.81.21.42.0
Pavlov. Cond. lever latency6.78.411.3-2.8-3.0-3.3-2.9-2.6-3.0-3.0-2.6-3.0-3.1-2.2-2.8-3.4
Pavlov. Cond. magazine entry latency0.50.60.90.70.80.80.60.80.80.90.50.80.80.60.90.8
Pavlov. Cond. change in total contacts2.42.63.51.51.71.81.61.51.71.71.41.71.71.21.51.9
Pavlov. Cond. index score3.34.25.12.02.12.21.92.02.12.31.72.12.21.62.12.2
Pavlov. Cond. latency score3.03.84.61.92.02.11.91.92.02.11.72.02.11.62.02.1
Pavlov. Cond. lever contacts5.36.37.82.42.62.72.62.32.52.62.42.52.62.02.42.8
Pavlov. Cond. magazine entry number0.91.11.4-1.0-1.1-1.1-0.9-1.1-1.2-1.1-0.8-1.1-1.1-0.9-1.1-1.1
Pavlov. Cond. intertrial magazine entries0.30.30.40.50.60.50.50.60.60.60.40.60.60.60.60.6
Pavlov. Cond. lever-magazine prob. diff.3.34.25.12.02.12.11.92.12.12.21.72.12.11.82.12.1
Pavlov. Cond. response bias3.23.94.71.92.02.11.91.82.02.11.72.02.11.61.92.2
Bone: apparent density1.52.52.91.71.61.61.71.61.61.51.71.51.51.61.61.5
Bone surface0.61.01.51.01.01.21.10.91.00.91.11.01.00.70.91.2
Bone volume0.71.21.51.21.11.21.11.01.10.91.21.11.10.91.11.2
Bone: connectivity density0.91.52.31.31.21.11.41.21.11.21.51.01.01.41.21.0
Bone: cortical apparent density0.20.20.90.50.30.00.40.60.40.20.50.40.30.90.5-0.3
Bone: cortical area2.94.45.02.22.12.12.02.22.12.01.92.22.22.02.22.0
Bone: cortical porosity0.40.50.7-0.7-0.7-0.8-0.7-0.5-0.8-0.6-0.6-0.8-0.8-0.5-0.7-0.7
Bone: cortical porosity0.00.00.0-0.0-0.0-0.10.10.0-0.20.00.1-0.2-0.10.1-0.1-0.0
Bone: cortical thickness1.52.43.61.71.51.31.61.71.51.31.71.61.51.91.61.1
Bone: cortical thickness0.00.00.10.0-0.2-0.2-0.20.1-0.0-0.3-0.20.0-0.10.00.0-0.4
Bone: cortical tissue density0.10.10.60.40.2-0.10.20.40.30.10.30.30.20.80.4-0.4
Bone: elastic displacement3.03.46.0-1.6-1.9-2.3-1.6-1.6-2.0-2.0-1.3-1.9-2.1-0.9-1.7-2.5
Bone: elastic work0.50.62.6-0.3-0.7-1.3-0.4-0.1-0.7-0.8-0.1-0.7-0.90.6-0.3-1.6
Bone: endosteal estimation0.61.32.61.01.11.50.81.01.21.10.61.21.40.31.11.6
Bone: endosteal perimeter0.51.12.60.91.01.50.80.81.11.10.61.11.30.20.91.6
Bone: final force1.22.02.51.41.41.61.11.61.51.30.91.51.50.91.61.5
Bone: final moment1.01.62.31.31.31.40.91.51.41.20.71.41.40.91.51.3
Bone: marrow area0.71.52.81.21.31.60.91.21.31.20.71.41.50.51.21.7
Bone: maximum diameter2.34.35.22.12.12.21.82.22.12.11.62.22.31.72.12.2
Bone: maximum force3.05.26.02.32.42.52.02.42.42.31.72.42.41.72.42.4
Bone: maximum moment2.44.25.22.12.12.21.82.32.22.01.62.22.21.62.22.1
Bone: minimum diameter0.00.00.00.10.0-0.10.00.2-0.10.00.1-0.00.00.20.1-0.1
Bone: periosteal estimation1.42.93.81.71.72.01.41.81.81.61.21.91.91.11.82.0
Bone: periosteal perimeter0.20.41.00.50.60.90.50.40.60.60.30.70.80.10.51.0
Bone: post-yield work0.81.12.40.91.11.40.81.01.11.20.51.11.20.31.01.5
Bone: stiffness3.86.17.52.42.62.71.92.72.72.51.52.72.71.72.72.7
Bone: tissue strength0.20.20.40.30.40.3-0.10.60.60.5-0.40.50.5-0.00.60.3
Bone: trabecular number1.72.62.91.71.71.51.71.71.61.61.61.51.51.71.61.5
Bone: trabecular spacing0.00.10.20.30.20.10.20.30.20.10.20.30.20.40.3-0.1
Bone: trabecular thickness0.10.10.2-0.2-0.2-0.4-0.1-0.1-0.4-0.1-0.1-0.4-0.3-0.0-0.2-0.3
Bone: trabecular tissue density2.13.04.41.61.82.01.21.72.01.90.72.02.11.01.92.0
Breakpoint value in progressive ratio session1.11.22.2-1.3-1.1-0.7-0.8-1.5-1.2-0.9-0.8-1.2-1.1-1.3-1.4-0.5
Distance traveled before self-admin3.23.45.71.71.82.41.61.42.11.71.52.12.11.11.62.4
Distance traveled after self-admin0.90.91.70.90.90.90.71.11.30.80.61.31.20.71.10.8
Delta time in closed arm before/after self-admin4.03.94.62.02.11.81.82.12.02.11.72.02.12.12.11.7
Delta time in open arm before/after self-admin0.90.81.1-1.1-0.9-0.8-0.7-1.0-1.0-0.8-0.9-1.0-1.0-0.9-1.0-0.7
Diff in mean of infusions in LGA sessions0.00.00.0-0.1-0.1-0.2-0.10.0-0.1-0.00.0-0.1-0.00.0-0.0-0.2
Extinction: sum of active levers before priming2.12.12.7-1.6-1.5-1.5-1.5-1.4-1.5-1.2-1.3-1.5-1.5-1.3-1.5-1.5
Active lever presses in extinction session 60.60.51.1-0.8-0.7-0.7-0.3-0.7-1.1-0.6-0.1-1.1-0.9-0.5-0.8-0.6
Delta distance traveled before/after self-admin0.50.51.0-0.7-0.7-0.9-0.9-0.4-0.5-0.8-1.0-0.5-0.5-0.7-0.5-0.9
Delta ambulatory time before/after self-admin1.41.52.3-1.2-1.2-1.5-1.5-0.8-1.0-1.3-1.5-1.0-1.0-1.1-0.9-1.5
Time in closed arm before self-admin2.42.73.7-1.6-1.7-1.8-1.3-1.6-1.8-1.7-1.0-1.8-1.9-1.3-1.7-1.9
Time in closed arm after self-admin0.00.00.10.1-0.0-0.30.00.10.0-0.1-0.00.0-0.00.20.1-0.3
Time in open arm before self-admin1.31.43.01.11.21.60.90.91.11.21.01.11.30.51.01.7
Time in open arm after self-admin0.60.61.50.60.81.11.00.40.60.81.00.60.70.50.51.2
Sum of active levers in priming session hrs 5-64.34.25.4-2.2-2.1-2.1-1.7-2.2-2.3-1.9-1.6-2.3-2.2-1.9-2.2-1.9
Time to tail flick, vehicle, before self-admin1.01.01.6-1.0-1.0-1.1-0.8-1.0-1.2-1.1-0.4-1.2-1.1-0.5-1.0-1.3
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.1-0.1-0.1-0.30.00.10.00.0-0.0-0.0-0.2-0.0
Time to tail flick, test, before self-admin0.40.40.70.80.70.50.60.70.50.70.80.50.40.80.70.5
Time to tail flick, test, after self-admin1.41.42.31.31.21.01.41.31.01.21.41.01.01.51.20.8
Delta time to tail flick, vehicle, before/after SA0.20.20.50.40.40.40.10.40.60.7-0.10.60.50.20.40.5
Delta time to tail flick, test, before/after SA0.00.00.1-0.0-0.1-0.10.2-0.10.0-0.10.20.00.00.1-0.1-0.2
Ambulatory time before self-admin2.02.14.11.31.42.01.51.01.51.31.31.51.50.81.12.0
Ambulatory time after self-admin0.10.10.20.20.30.40.30.30.50.20.20.50.50.00.30.4
Total heroin consumption0.91.11.9-1.2-1.1-0.8-0.9-1.4-1.0-1.0-0.9-1.0-0.9-1.2-1.3-0.7
Area under the delay curve0.80.81.2-1.1-0.9-0.7-0.7-1.1-1.1-0.7-0.8-1.1-0.9-0.9-1.1-0.7
Delay disc. indifference point, 0s delay1.92.02.4-1.5-1.5-1.3-1.5-1.4-1.5-1.3-1.4-1.5-1.4-1.4-1.5-1.3
Delay disc. indifference point, 16s delay2.22.23.3-1.6-1.5-1.1-1.1-1.8-1.6-1.7-1.2-1.6-1.5-1.6-1.7-1.1
Delay disc. indifference point, 2s delay0.10.10.20.30.30.10.30.40.20.30.20.20.20.50.30.1
Delay disc. indifference point, 24s delay0.20.10.4-0.4-0.4-0.4-0.5-0.3-0.3-0.3-0.6-0.3-0.3-0.4-0.3-0.4
Delay disc. indifference point, 4s delay0.10.10.2-0.4-0.3-0.3-0.2-0.3-0.4-0.2-0.2-0.4-0.3-0.2-0.3-0.3
Delay disc. indifference point, 8s delay0.00.00.1-0.10.10.10.2-0.0-0.00.30.0-0.00.00.1-0.00.1
Delay discount exponential model param0.60.71.01.00.80.60.61.00.90.60.70.90.80.80.90.6
Delay discount hyperbolic model param0.50.60.80.90.70.60.50.90.90.60.60.90.80.70.90.5
Fecal boli incidents, locomotor time 10.40.40.8-0.7-0.6-0.9-0.5-0.5-0.6-0.5-0.4-0.7-0.9-0.2-0.6-0.9
Change in fecal boli incidents, locomotor task0.40.41.00.70.61.00.50.40.40.20.70.50.70.00.41.0
Time >=10cm from walls, locomotor time 10.10.10.3-0.3-0.3-0.0-0.5-0.5-0.3-0.4-0.4-0.3-0.2-0.6-0.40.1
Bouts of movement, locomotor time 11.61.82.4-1.4-1.4-1.6-1.4-1.1-1.4-1.3-1.2-1.4-1.3-1.1-1.3-1.5
Total resting periods, locomotor time 11.71.93.0-1.4-1.4-1.7-1.4-1.0-1.4-1.2-1.3-1.4-1.4-0.9-1.2-1.7
Rest time, locomotor task time 10.40.41.7-0.2-0.4-1.3-0.70.3-0.3-0.4-0.5-0.3-0.60.20.0-1.3
Distance moved, locomotor task time 10.70.82.40.80.81.51.00.30.80.60.80.70.90.10.51.5
Vertical activity count, locomotor time 10.20.21.20.10.20.90.1-0.20.2-0.0-0.30.20.4-0.70.01.1
Time >=10cm from walls, locomotor time 20.00.10.10.10.20.30.00.10.30.3-0.10.30.30.10.10.3
Bouts of movement, locomotor time 20.60.61.00.60.80.80.80.70.70.91.00.70.80.70.70.8
Total resting periods, locomotor time 20.30.30.70.40.50.50.60.40.40.70.90.40.40.60.40.5
Rest time, locomotor task time 20.60.71.2-0.6-0.8-1.1-0.9-0.5-0.9-0.9-0.7-0.9-1.0-0.6-0.6-1.1
Distance moved, locomotor task time 20.70.81.30.80.90.80.81.01.10.90.41.01.00.71.00.7
Vertical activity count, locomotor time 20.30.40.80.50.60.80.20.50.90.5-0.10.70.80.10.60.8
Weight adjusted by age0.00.00.2-0.2-0.10.20.2-0.4-0.0-0.1-0.1-0.2-0.0-0.2-0.30.4
Seeking ratio, delayed vs. immediate footshock4.75.47.62.12.32.32.61.92.22.52.82.32.32.52.02.2
Locomotion in novel chamber0.10.10.40.30.3-0.00.50.40.00.40.60.00.00.60.4-0.1
Locomotion in novel chamber post-restriction2.83.44.62.01.91.61.72.11.71.91.81.71.72.02.11.4
Progressive ratio0.00.00.1-0.3-0.2-0.1-0.0-0.3-0.20.10.0-0.2-0.2-0.2-0.2-0.1
Food seeking constrained by brief footshock4.65.610.22.22.43.12.51.72.02.42.42.22.51.71.93.2
Seeking ratio, punishment vs. effort1.31.62.61.41.31.61.21.11.11.11.11.21.41.01.21.6
Run reversals in cocaine runway, females0.20.20.60.60.50.30.40.80.40.40.40.40.30.60.70.2
Run reversals in cocaine runway, males0.00.00.1-0.1-0.0-0.10.2-0.1-0.20.10.4-0.1-0.00.2-0.1-0.1
Latency to leave start box in cocaine runway0.91.01.21.11.01.01.01.01.10.91.11.11.11.01.00.9
Latency to leave start box in cocaine runway, F0.00.00.0-0.1-0.1-0.00.1-0.2-0.0-0.20.1-0.1-0.1-0.1-0.1-0.1
Latency to leave start box in cocaine runway, M1.00.91.61.01.01.30.70.81.10.80.81.11.10.50.91.3
Cd content in liver1.11.21.91.21.11.11.01.41.21.00.91.21.10.91.30.9
Co content in liver1.92.33.7-1.4-1.5-1.4-1.8-1.4-1.4-1.6-1.9-1.4-1.4-1.7-1.4-1.3
Cu content in liver0.70.81.8-0.7-0.9-1.1-1.3-0.5-0.6-1.0-1.3-0.6-0.8-0.7-0.5-1.2
Fe content in liver0.40.52.2-0.7-0.50.0-0.9-0.7-0.4-0.4-1.0-0.4-0.3-1.5-0.60.2
K content in liver0.60.61.1-0.8-0.8-0.6-0.8-0.8-0.7-0.7-0.9-0.7-0.7-1.1-0.8-0.5
Mg content in liver0.70.71.0-0.8-0.8-0.9-0.7-0.8-1.0-0.6-0.8-1.0-0.9-0.7-0.9-0.7
Mn content in liver0.40.40.70.70.70.40.60.70.60.80.50.60.60.80.80.4
Na content in liver1.81.93.9-1.3-1.3-1.3-2.0-1.0-1.0-1.3-2.0-1.0-1.2-1.6-1.0-1.3
Rb content in liver4.75.87.4-2.3-2.5-2.5-2.5-2.1-2.4-2.7-2.4-2.4-2.5-2.3-2.3-2.5
Se content in liver2.32.84.21.51.71.61.51.71.82.11.31.81.81.51.71.5
Sr content in liver0.50.51.20.60.80.70.50.60.61.10.40.60.80.70.60.7
Zn content in liver0.40.40.70.70.60.30.90.80.50.60.80.50.40.80.70.3