Hub : Genes

Usf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	mRNA stability	ENSRNOG00000053725	0.04	0.02	1.4e-04	0.03	0.02	0.02	0.02	1.4e-04	1.7e-03	1.4e-03	1.7e-03
2	BLA	gene expression	ENSRNOG00000053725	0.16	0.09	2.0e-05	0.06	0.08	0.07	0.07	5.7e-04	3.8e-05	2.1e-04	1.6e-04
3	Brain	gene expression	ENSRNOG00000053725	0.06	0.04	6.9e-05	0.04	0.04	0.04	0.04	6.4e-05	3.0e-04	1.9e-04	1.6e-04
4	Liver	gene expression	ENSRNOG00000053725	0.04	0.03	1.4e-04	0.02	0.02	0.02	0.02	2.3e-03	5.3e-03	4.9e-03	4.5e-03
5	NAcc	gene expression	ENSRNOG00000053725	0.04	0.03	7.5e-03	0	-0	-0	-0	2.2e-01	4.3e-01	5.1e-01	5.9e-01
6	PL	gene expression	ENSRNOG00000053725	0.06	0.04	5.5e-04	0.04	0.03	0.04	0.03	5.0e-04	1.6e-03	7.7e-04	2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.1	0.3	0.6	0.5	-0.5	-0.0	-0.5	-0.4	-0.8
BMI without tail	0.0	0.0	0.1	0.0	-0.4	0.2	-0.1	0.1	-0.0
Body weight	2.6	11.1	16.5	-2.6	3.5	4.1	2.5	3.4	3.6
Epididymis fat weight	0.1	0.3	0.7	-0.1	0.4	0.8	-0.3	0.7	0.6
Glucose	0.1	0.1	0.3	-0.3	-0.2	-0.6	0.2	-0.2	-0.1
Heart weight	0.2	0.3	0.6	0.5	0.3	0.3	-0.6	0.8	0.5
Left kidney weight	4.2	12.0	17.4	-3.5	4.2	3.1	3.7	2.9	3.2
Right kidney weight	5.7	16.3	21.4	-3.8	4.6	4.1	4.1	3.6	4.0
Tail length	3.0	9.1	13.8	-2.5	2.9	3.2	2.4	3.1	3.7
Length with tail	5.9	21.7	31.7	-3.5	4.8	5.2	3.2	5.0	5.6
Length without tail	4.9	10.7	15.1	-2.1	3.6	3.9	2.0	3.6	3.8
Liver weight, left	0.2	0.3	0.9	-0.7	0.2	-0.2	0.9	-0.2	-0.8
Liver weight, right	0.2	0.3	0.7	0.0	-0.2	-0.3	0.4	-0.8	-0.7
Parametrial fat weight	1.7	3.3	8.6	-2.9	1.5	0.4	2.9	-0.2	-0.3
Retroperitoneal fat weight	0.4	1.2	3.1	-0.7	-0.4	-1.4	0.5	-1.2	-1.8
Intraocular pressure	0.2	0.3	0.7	0.7	-0.7	-0.4	-0.9	0.2	-0.1
Extensor digitorum longus weight	0.7	2.8	5.9	-2.4	1.8	1.5	2.2	0.5	-0.2
Soleus weight	0.1	0.2	0.4	-0.7	0.3	0.0	0.2	-0.5	-0.4
Tibialis anterior weight	0.8	2.8	6.2	-2.5	1.6	1.5	2.3	0.6	0.3
Tibia length	3.0	8.4	14.6	-1.7	2.9	3.8	1.6	3.4	3.2
Number of licking bursts	3.2	3.8	6.6	2.6	-2.1	-1.7	-1.9	-1.7	-1.7
Food consumed during 24 hour testing period	0.5	0.6	1.0	1.0	-0.2	0.7	-0.8	0.7	0.8
Times rat made contact with spout	0.1	0.1	0.6	-0.2	0.0	-0.2	0.8	0.0	-0.2
Mean time between licks in bursts	0.3	0.4	1.1	0.7	-0.6	0.0	-1.1	-0.2	-0.4
Mean num. licks in bursts	2.7	3.3	5.7	-2.4	1.9	1.4	2.1	1.5	1.3
Std. dev. time between licks in bursts	1.9	2.2	5.5	2.0	-1.6	-0.7	-2.3	-0.9	-0.3
Water consumed over 24 hours	0.6	0.7	1.5	-0.4	0.8	1.2	0.7	0.9	0.8
Indifference point 0 sec	0.2	0.3	0.8	0.8	-0.5	-0.1	-0.9	-0.1	0.1
Indifference point AUC	0.2	0.3	0.6	-0.1	-0.2	-0.7	0.2	-0.8	-0.7
Indifference point function ln k	0.2	0.3	1.0	-0.0	0.1	1.0	-0.4	0.6	0.7
Indifference point function log k	0.2	0.3	1.0	-0.0	0.1	1.0	-0.4	0.6	0.7
Delay discounting total patch changes 0 sec	0.2	0.3	0.7	0.8	-0.3	0.1	-0.8	0.1	0.3
Delay discounting total patch changes 12 sec	0.2	0.3	0.5	0.1	-0.5	-0.7	-0.1	-0.7	-0.6
Delay discounting total patch changes 18 sec	0.2	0.3	0.7	0.8	-0.5	-0.3	-0.8	-0.1	0.2
Delay discounting total patch changes 24 sec	0.6	0.7	1.4	0.4	0.7	1.0	-0.1	1.2	1.2
Delay discounting total patch changes 6 sec	0.1	0.1	0.2	0.3	-0.2	-0.5	-0.3	-0.4	-0.1
Delay discounting time to switch 0 sec	0.6	0.9	1.6	-0.5	-0.5	-1.2	0.9	-1.2	-1.1
Delay discounting water rate 0 sec	0.8	1.3	2.6	1.3	-0.9	-0.9	-1.6	-1.0	-1.0
Delay discounting water rate 12 sec	0.7	1.1	2.1	1.5	-0.4	0.1	-1.5	0.8	1.3
Delay discounting water rate 18 sec	0.7	0.9	1.3	1.1	-0.8	-1.1	-1.1	-0.7	-0.5
Delay discounting water rate 24 sec	1.9	2.6	7.2	2.6	-1.3	0.0	-2.7	0.1	0.2
Delay discounting water rate 6 sec	0.8	1.2	2.0	1.2	0.3	0.9	-1.3	1.2	1.4
Locomotor activity	0.4	0.6	1.3	-0.0	-0.5	-1.1	0.1	-1.1	-1.0
Locomotor testing distance	0.4	0.7	1.6	0.4	-0.8	-1.3	-0.4	-1.0	-0.7
Locomotor testing rearing	1.5	2.3	2.9	1.3	-1.7	-1.6	-1.5	-1.7	-1.3
Light reinforcement 1	0.6	1.0	2.2	1.5	-1.0	-0.6	-1.4	-0.7	-0.3
Light reinforcement 2	1.5	2.0	4.4	0.9	-1.3	-1.0	-1.2	-1.7	-2.1
Reaction time number correct	0.1	0.1	0.3	-0.4	0.5	0.2	0.0	0.3	0.1
Reaction time mean minus median	0.5	0.7	0.9	-0.9	0.7	0.7	0.8	0.9	0.8
Reaction time mean minus median AUC	1.3	1.6	1.9	-1.4	1.3	1.0	1.3	1.3	1.2
Reaction time num false alarms	0.5	0.7	1.5	0.4	-0.9	-1.2	-0.1	-0.9	-0.9
Reaction time num false alarms AUC	0.8	1.1	2.4	0.6	-1.1	-1.5	-0.3	-1.1	-1.1
Reaction time trials correct on left	0.1	0.1	0.3	-0.4	0.5	0.2	0.0	0.3	0.1
Reaction time trials on left	0.1	0.1	0.3	-0.4	0.5	0.2	0.0	0.3	0.1
Reaction time mean	0.1	0.2	0.4	-0.0	-0.0	0.5	-0.1	0.6	0.7
Reaction time mean AUC	0.0	0.1	0.2	0.0	-0.2	0.2	-0.1	0.3	0.4
Median of all reaction times	0.1	0.1	0.2	0.5	-0.4	0.2	-0.4	0.2	0.4
Reaction time omissions	0.0	0.0	0.1	-0.2	-0.3	-0.2	0.1	-0.1	-0.1
Reaction time false alarm rate	0.7	0.9	1.8	0.7	-1.2	-1.3	-0.4	-1.0	-0.9
Reaction time premature initiation rate	0.7	0.9	2.1	1.5	-0.9	-0.7	-1.2	-0.8	-0.2
Reaction time premature initiations	0.4	0.5	1.2	1.1	-0.5	-0.5	-1.0	-0.6	-0.2
Std. dev. reaction times	0.5	0.7	1.6	-0.4	0.6	0.9	0.3	1.3	1.1
Reaction time trials completed	0.1	0.1	0.3	-0.4	0.5	0.2	0.0	0.3	0.1
Reaction time trials AUC	0.1	0.2	0.5	-0.7	0.6	0.2	0.3	0.2	0.0
Social response proportion	1.9	2.0	3.4	-1.4	1.5	1.4	1.2	1.8	1.0
Social responses	0.3	0.4	0.8	-0.8	0.9	0.4	0.9	0.4	0.1
Social time	1.7	2.3	4.7	-0.3	1.3	1.9	0.3	2.2	1.9
Conditioned locomotion	0.4	0.5	1.2	0.6	-0.8	-0.5	-0.6	-0.6	-1.1
Cocaine response after cond. corrected	0.5	0.6	1.7	-1.1	0.6	-0.5	1.3	-0.0	-0.3
Cocaine response after cond. not corrected	0.6	0.7	1.8	-1.2	0.5	-0.7	1.3	-0.3	-0.2
Cocaine response before conditioning	0.3	0.4	1.8	0.0	0.1	0.4	-0.3	0.3	1.4
Saline control response	0.0	0.1	0.2	-0.3	0.0	0.2	0.5	-0.2	0.1
Condit. Reinf. active minus inactive responses	0.5	0.6	1.2	-0.7	0.7	1.1	0.2	0.5	1.1
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	-0.3	-0.1	-0.1	-0.2	-0.3	-0.1
Condit. Reinf. active responses	1.1	1.5	3.7	-0.5	1.2	1.5	0.1	1.2	1.9
Condit. Reinf. inactive responses	1.1	1.4	3.7	0.3	0.9	1.3	-0.2	1.4	1.9
Condit. Reinf. lever presses	3.8	5.3	8.4	-1.6	2.4	2.7	1.3	2.4	2.9
Condit. Reinf. lever reinforcers received	1.1	1.6	4.3	-0.2	1.1	1.5	-0.2	1.3	2.1
Pavlov. Cond. lever latency	2.7	3.7	6.3	0.8	-2.0	-2.5	-0.9	-2.2	-2.5
Pavlov. Cond. magazine entry latency	0.8	0.9	2.0	-0.3	1.0	1.1	0.5	1.0	1.4
Pavlov. Cond. change in total contacts	4.3	6.0	11.4	-0.9	2.3	2.8	0.9	3.1	3.4
Pavlov. Cond. index score	2.4	3.1	6.0	-0.6	1.7	2.2	0.8	1.9	2.5
Pavlov. Cond. latency score	2.1	2.6	5.2	-0.5	1.6	2.0	0.7	1.8	2.3
Pavlov. Cond. lever contacts	2.5	3.5	6.2	-0.6	1.9	2.4	0.7	2.2	2.5
Pavlov. Cond. magazine entry number	2.2	2.7	5.1	0.8	-1.7	-2.0	-0.9	-1.8	-2.3
Pavlov. Cond. intertrial magazine entries	0.3	0.3	0.9	-0.1	-0.4	-0.7	-0.2	-0.7	-0.9
Pavlov. Cond. lever-magazine prob. diff.	2.4	3.1	6.0	-0.7	1.8	2.1	0.9	1.9	2.4
Pavlov. Cond. response bias	2.8	3.8	7.4	-0.4	1.9	2.5	0.5	2.3	2.7
Conditioned reinforcement - actives	0.8	0.8	1.5	0.9	-0.7	-1.0	-0.8	-1.2	-0.3
Conditioned reinforcement - inactives	1.1	1.2	4.2	1.5	-0.5	0.5	-2.1	0.2	0.3
Conditioned locomotion	2.6	3.1	3.7	1.9	-1.6	-1.7	-1.7	-1.9	-1.7
Intermittent access intake day 1-15 change	2.4	2.4	3.5	-1.3	1.7	1.9	1.0	1.5	1.8
Intermittent access intake escalation	2.5	2.4	3.8	-1.2	1.7	2.0	0.9	1.6	1.8
Intermittent access intake escalation 2	1.2	1.2	1.7	-1.1	1.1	1.1	0.8	1.0	1.3
Intermitt. access day 1 inactive lever presses	2.1	2.2	2.9	-1.3	1.7	1.7	1.1	1.6	1.3
Intermitt. access day 15 inactive lever presses	0.1	0.1	0.5	0.0	0.5	0.7	-0.2	0.2	0.2
Intermitt. access escalation Index	0.5	0.4	1.4	0.8	-0.6	0.0	-1.2	0.0	-0.1
Intermittent access day 1 total infusions	4.5	5.1	8.6	2.9	-2.3	-1.7	-2.9	-1.8	-1.4
Intermittent access day 15 total infusions	1.4	1.5	4.2	1.9	-0.9	-0.1	-2.1	-0.5	0.1
Intermittent access terminal intake (last 3 days)	2.5	2.7	6.3	2.4	-1.6	-0.7	-2.5	-1.0	-0.4
Intermittent access total infusions	3.3	3.7	7.9	2.7	-2.1	-1.0	-2.8	-1.2	-0.5
Intermittent access day 1 locomotion	3.1	3.2	6.4	2.5	-1.7	-1.1	-2.5	-1.2	-1.1
Intermittent access day 15 total locomotion	1.3	1.4	4.5	1.9	-0.6	-0.1	-2.1	-0.3	0.1
Intermittent access total locomotion	2.8	3.1	5.4	2.3	-1.7	-1.3	-2.3	-1.4	-1.2
Intermittent access standard deviation	2.3	2.4	5.3	-0.3	1.1	2.1	0.1	1.9	2.3
Cocaine induced anxiety	0.9	1.0	2.3	-0.7	1.5	0.8	1.4	0.8	0.5
Post-drug Anxiety	0.3	0.4	1.1	-0.1	0.7	-0.3	1.1	-0.4	-0.7
Baseline Anxiety	1.5	1.6	2.2	0.8	-1.5	-1.2	-1.2	-1.5	-1.4
Lifetime Intake	2.5	2.7	5.6	2.1	-1.8	-1.0	-2.4	-1.2	-0.6
Incentive Sensitization - Responses	0.4	0.4	1.1	0.8	-0.4	-0.1	-1.1	-0.5	0.0
Incentive Sensitization - Breakpoint	0.3	0.3	0.8	0.6	-0.3	-0.0	-0.9	-0.4	0.1
Progressive ratio test 1 active lever presses	0.9	1.0	2.6	1.6	-0.1	0.3	-1.5	0.4	0.8
Progressive ratio test 1 breakpoint	0.7	0.7	1.4	1.2	0.2	0.5	-1.0	0.6	1.0
Progressive ratio test 1 inactive lever presses	0.8	0.9	2.3	1.5	-0.6	0.4	-1.5	0.0	0.3
Progressive ratio test 2 active lever presses	1.1	1.1	3.0	1.7	-0.7	-0.1	-1.7	-0.4	0.3
Progressive ratio test 2 breakpoint	1.1	1.2	3.0	1.7	-0.8	-0.3	-1.7	-0.6	0.2
Progressive ratio test 2 inactive lever presses	1.3	1.5	4.7	1.9	-0.5	0.9	-2.2	0.2	0.3
Total sessions with >9 infusions	1.5	1.7	2.4	1.3	-1.6	-1.4	-1.3	-1.3	-0.9
Short access day 1 total inactive lever presses	0.8	0.9	2.6	1.6	-0.3	0.5	-1.5	0.3	-0.0
Short access day 10 total inactive lever presses	1.0	1.1	2.3	-0.5	1.0	1.5	0.4	1.4	0.8
Short access day 1 total infusions	0.5	0.5	1.6	0.8	-0.9	-0.3	-1.3	-0.4	-0.2
Short access day 10 total infusions	0.6	0.7	1.0	0.8	-1.0	-0.7	-0.9	-0.9	-0.4
Short access total infusions	1.1	1.3	1.7	1.0	-1.3	-1.1	-1.2	-1.2	-0.7
Short access day 1 locomotion	0.2	0.2	0.3	0.2	-0.5	-0.3	-0.4	-0.5	-0.4
Short access day 10 total locomotion	0.7	0.7	2.1	1.3	-0.7	0.0	-1.5	0.1	0.5
Short access total locomotion	1.6	1.6	2.2	1.1	-1.5	-1.2	-1.3	-1.3	-1.1
Compulsive drug intake	0.0	0.0	0.1	0.3	0.1	-0.2	-0.2	-0.1	0.2
One hour access (0.3 mA shock)	1.8	2.1	6.0	2.2	-0.9	0.1	-2.5	-0.0	1.1
One hour access (shock baseline)	1.3	1.5	4.0	1.7	-1.2	-0.3	-2.0	-0.6	0.1
Number of responses in last shaping day	1.8	1.8	5.1	1.9	-1.3	-0.4	-2.3	-0.3	-0.1
Context. condit. distance diff. score	0.3	0.3	1.0	0.7	-0.4	0.1	-1.0	0.5	0.1
Locomotion velocity, session 1	0.2	0.2	0.7	-0.2	-0.1	-0.6	0.1	-0.8	-0.5
Locomotion distance, session 1	0.5	0.7	1.7	0.5	0.3	1.3	-0.7	0.7	1.0
Locomotion velocity, session 2	1.3	1.5	3.5	1.0	-1.2	-1.1	-0.9	-1.9	-1.1
Locomotion distance, session 2	1.8	2.6	4.7	2.0	-1.6	-0.3	-2.2	-1.7	-1.2
Locomotion velocity, session 3	0.5	0.6	1.0	0.8	-0.9	-0.3	-0.9	-1.0	-0.4
Locomotion distance, session 3	1.5	1.7	4.3	0.9	0.5	2.1	-0.9	1.2	1.6
Stereotopy head waving bouts, day 3	0.7	0.8	1.2	-1.0	-0.1	-0.9	0.9	-1.1	-1.1
Stereotopy head waving duration, day 3	1.0	1.2	2.5	-0.8	-0.4	-1.3	0.8	-1.3	-1.6
Locomotion velocity, session 7	0.3	0.4	0.6	0.5	0.5	0.8	-0.4	0.6	0.7
Locomotion distance, session 7	0.2	0.2	0.5	0.1	0.4	0.7	-0.2	0.2	0.7
Stereotopy head waving bouts, day 7	2.3	2.6	4.3	2.1	-1.7	-1.4	-2.0	-1.1	-1.1
Stereotopy head waving duration, day 7	2.0	2.4	3.1	1.5	-1.6	-1.6	-1.3	-1.5	-1.8
Locomotion velocity, session 8	4.0	4.8	5.7	2.2	-2.4	-2.2	-2.2	-2.0	-2.0
Locomotion distance, session 8	2.0	3.0	7.4	2.4	-1.8	-0.5	-2.7	-0.9	-0.7
Degree of sensitization distance	0.4	0.4	1.1	-0.8	0.1	-1.1	0.7	-0.5	-0.4
Degree of sensitization stereotypy	3.0	3.3	6.0	2.4	-2.0	-1.4	-2.3	-1.1	-1.1
Condit. Reinf. active minus inactive responses	0.1	0.2	0.5	0.4	-0.3	0.1	-0.4	-0.3	-0.7
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.7	-0.7	0.2	-0.0	0.7	-0.3	-0.8
Condit. Reinf. active responses	1.4	1.7	3.1	1.4	-1.2	-0.7	-1.3	-1.3	-1.7
Condit. Reinf. inactive responses	2.3	2.7	4.6	2.1	-1.5	-1.0	-1.9	-1.5	-1.5
Incentive salience index mean	0.3	0.3	0.6	0.7	-0.4	0.0	-0.6	-0.6	-0.8
Condit. Reinf. lever presses	0.2	0.2	0.6	0.7	-0.2	0.2	-0.6	-0.4	-0.4
Time in familiar zone, hab. session 1	3.4	3.2	5.2	-2.1	2.2	1.6	2.3	1.2	0.9
Time in novel zone, hab. session 1	5.2	5.1	7.5	2.5	-2.7	-2.1	-2.7	-1.6	-1.6
Total zone transitions, hab. session 1	0.3	0.5	1.4	1.0	-0.6	0.3	-1.2	-0.1	0.0
Total locomotion distance, hab. session 1	0.4	0.5	1.2	0.9	-0.8	-0.1	-1.1	0.0	0.7
Locomotion velocity, hab. session 1	0.2	0.3	0.5	0.7	-0.7	-0.3	-0.7	-0.2	0.5
Time in familiar zone, hab. session 2	1.5	1.5	3.1	-1.4	1.3	0.3	1.8	1.0	0.9
Time in novel zone, hab. session 2	0.9	0.9	1.3	0.9	-1.1	-0.4	-1.2	-1.0	-0.8
Total zone transitions, hab. session 2	4.3	5.5	7.1	2.4	-2.7	-1.9	-2.6	-2.3	-2.1
Total locomotion distance, hab. session 2	2.2	2.9	5.1	2.1	-2.0	-1.4	-2.3	-1.0	-0.8
Locomotion velocity, hab. session 2	1.9	2.5	4.3	1.9	-1.9	-1.3	-2.1	-1.1	-0.9
Novel to familiar place preference ratio	0.1	0.1	0.2	0.3	0.2	0.0	-0.1	0.5	0.4
Novelty place preference	0.1	0.1	0.2	0.5	-0.1	-0.3	-0.4	0.4	0.3
Time in novel zone, NPP test	0.2	0.2	0.4	0.7	-0.3	-0.4	-0.5	0.3	0.2
Total zone transitions, NPP test	0.1	0.2	0.5	0.4	-0.4	0.4	-0.7	-0.4	-0.1
Total locomotion distance, NPP test	0.6	0.9	2.7	-0.4	0.4	1.1	0.1	1.0	1.6
Locomotion velocity, NPP test	0.6	0.8	2.7	-0.5	0.5	1.0	0.3	0.8	1.6
Pavlov. Cond. lever latency	1.4	1.8	2.8	-1.5	1.7	0.9	1.5	1.5	0.8
Pavlov. Cond. magazine entry latency	3.1	4.0	6.5	2.2	-2.5	-1.8	-2.2	-2.0	-0.9
Pavlov. Cond. change in total contacts	3.7	3.9	7.2	2.7	-2.3	-1.0	-2.6	-1.6	-0.8
Pavlov. Cond. index score	3.2	4.1	6.4	2.2	-2.5	-1.7	-2.1	-2.1	-1.1
Pavlov. Cond. latency score	2.5	3.2	5.1	2.0	-2.3	-1.4	-2.0	-1.8	-0.9
Pavlov. Cond. lever contacts	1.0	1.2	2.0	1.4	-1.4	-0.5	-1.2	-1.1	-0.4
Pavlov. Cond. magazine entry number	3.4	4.2	6.8	-2.3	2.6	1.6	2.3	2.0	1.0
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.5	0.1	0.4	-0.3	0.1	-0.4	-0.7
Pavlov. Cond. lever-magazine prob. diff.	3.9	4.9	7.8	2.4	-2.8	-1.8	-2.4	-2.3	-1.3
Pavlov. Cond. response bias	1.8	2.3	3.7	1.6	-1.9	-1.2	-1.5	-1.8	-0.7
Bone: apparent density	1.1	1.8	2.6	-1.5	1.6	1.1	1.6	0.8	1.2
Bone surface	1.0	1.8	3.5	-1.0	1.3	1.6	0.7	1.3	1.9
Bone volume	1.4	2.4	3.8	-1.3	1.7	1.8	1.2	1.3	1.9
Bone: connectivity density	0.1	0.2	0.4	-0.5	0.6	0.2	0.6	0.1	0.6
Bone: cortical apparent density	0.8	1.1	1.8	1.0	-1.0	-0.8	-1.1	-0.9	-1.3
Bone: cortical area	1.2	1.8	2.5	-1.6	1.2	1.6	0.7	1.2	1.5
Bone: cortical porosity	4.2	4.6	6.4	2.5	-2.5	-1.7	-2.3	-2.0	-1.6
Bone: cortical porosity	4.7	5.1	7.5	2.7	-2.6	-1.7	-2.4	-2.2	-1.7
Bone: cortical thickness	0.5	0.8	1.9	-1.4	0.8	0.9	0.7	0.5	0.7
Bone: cortical thickness	0.3	0.4	0.8	-0.6	-0.3	-0.3	0.3	-0.9	-0.9
Bone: cortical tissue density	1.0	1.3	2.1	1.1	-1.1	-0.9	-1.2	-1.0	-1.5
Bone: elastic displacement	0.0	0.0	0.1	-0.3	0.1	-0.1	0.2	-0.2	-0.0
Bone: elastic work	1.5	2.0	2.9	-1.2	1.6	1.7	1.2	1.2	1.4
Bone: endosteal estimation	0.8	1.6	3.5	-0.7	1.0	1.5	0.4	1.5	1.9
Bone: endosteal perimeter	0.6	1.2	2.9	-0.4	0.8	1.2	0.0	1.3	1.7
Bone: final force	1.5	2.4	3.8	-1.4	1.5	2.0	0.9	1.7	1.6
Bone: final moment	2.0	3.2	5.3	-1.6	1.8	2.3	1.1	1.9	1.9
Bone: marrow area	0.8	1.7	3.5	-0.8	1.1	1.5	0.5	1.5	1.9
Bone: maximum diameter	1.1	2.0	2.3	-1.5	1.4	1.5	0.9	1.5	1.5
Bone: maximum force	2.2	3.8	5.6	-1.7	2.0	2.4	1.0	2.2	2.1
Bone: maximum moment	2.6	4.6	7.2	-1.8	2.1	2.7	1.1	2.4	2.4
Bone: minimum diameter	1.2	2.3	5.3	-0.5	1.2	1.8	0.1	1.9	2.3
Bone: periosteal estimation	1.3	2.7	4.3	-1.5	1.5	2.0	0.8	1.8	2.1
Bone: periosteal perimeter	0.6	1.1	1.9	-1.3	0.8	0.9	0.6	1.0	1.4
Bone: post-yield work	1.0	1.3	3.1	0.4	0.7	1.3	-0.5	1.8	1.5
Bone: stiffness	1.5	2.4	3.7	-1.5	1.5	1.8	0.9	1.9	1.4
Bone: tissue strength	2.3	2.2	4.4	-0.5	1.4	1.8	0.1	2.1	1.8
Bone: trabecular number	1.3	2.1	3.3	-0.9	1.6	1.8	1.1	1.4	1.7
Bone: trabecular spacing	0.1	0.2	0.7	-0.2	-0.3	-0.8	0.1	-0.3	0.1
Bone: trabecular thickness	0.3	0.4	0.8	-0.5	0.8	0.9	0.6	0.3	0.3
Bone: trabecular tissue density	1.1	1.5	2.8	-0.8	-0.5	-1.7	0.9	-1.6	-1.4
Breakpoint value in progressive ratio session	0.6	0.6	1.6	-0.1	0.8	1.1	0.0	1.3	0.6
Distance traveled before self-admin	0.0	0.0	0.1	0.2	-0.1	-0.3	-0.1	-0.1	0.0
Distance traveled after self-admin	1.4	1.6	3.5	-0.3	0.9	1.6	0.4	1.6	1.9
Delta time in closed arm before/after self-admin	3.6	3.5	4.6	-1.8	1.9	2.1	1.7	1.9	1.8
Delta time in open arm before/after self-admin	1.1	1.0	1.6	0.7	-1.2	-1.3	-0.7	-1.2	-0.9
Diff in mean of infusions in LGA sessions	0.7	0.8	1.2	1.1	-1.0	-0.6	-1.1	-0.4	-1.0
Extinction: sum of active levers before priming	4.6	4.6	6.1	-2.1	2.5	2.0	2.1	2.3	1.8
Active lever presses in extinction session 6	4.1	3.9	7.5	-2.7	2.1	1.1	2.7	1.1	1.4
Delta distance traveled before/after self-admin	2.8	3.0	5.1	-0.8	1.4	2.2	0.8	2.2	2.1
Delta ambulatory time before/after self-admin	3.0	3.3	5.9	-0.7	1.5	2.3	0.7	2.3	2.4
Time in closed arm before self-admin	2.8	3.1	3.8	1.9	-1.8	-1.6	-1.9	-1.6	-1.7
Time in closed arm after self-admin	0.1	0.1	0.4	-0.1	-0.0	0.7	0.0	0.3	-0.1
Time in open arm before self-admin	3.1	3.3	4.8	-1.7	1.9	1.6	1.7	1.8	2.2
Time in open arm after self-admin	0.3	0.4	1.5	-0.4	0.4	0.3	0.4	0.3	1.2
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.4	-0.6	0.7	0.4	0.6	0.6	0.3
Time to tail flick, vehicle, before self-admin	0.9	1.0	1.1	1.1	-0.8	-0.9	-1.1	-0.9	-1.1
Time to tail flick, vehicle, after self-admin	0.5	0.5	1.2	0.3	-1.1	-0.8	-0.3	-0.9	-0.5
Time to tail flick, test, before self-admin	1.5	1.5	4.1	2.0	-0.8	0.1	-2.0	0.2	-0.1
Time to tail flick, test, after self-admin	0.2	0.2	0.5	0.6	-0.3	-0.1	-0.7	0.2	-0.0
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.3	-0.0	-0.4	0.1	0.0	0.1	0.6
Delta time to tail flick, test, before/after SA	0.7	0.6	1.1	-0.9	-0.1	-1.0	0.9	-0.8	-0.6
Ambulatory time before self-admin	0.1	0.1	0.2	0.2	-0.2	-0.4	-0.1	-0.3	-0.2
Ambulatory time after self-admin	3.7	4.1	6.9	-0.7	1.8	2.6	0.8	2.6	2.6
Total heroin consumption	0.1	0.2	0.4	0.3	0.3	0.5	-0.2	0.6	0.4
Area under the delay curve	0.1	0.2	0.4	0.3	0.2	0.6	-0.2	0.6	0.2
Delay disc. indifference point, 0s delay	0.5	0.5	0.8	0.8	0.4	0.9	-0.7	0.9	0.2
Delay disc. indifference point, 16s delay	0.2	0.2	0.6	0.3	0.4	0.8	-0.1	0.5	0.3
Delay disc. indifference point, 2s delay	1.1	1.2	2.3	0.1	1.1	1.5	-0.0	1.5	1.1
Delay disc. indifference point, 24s delay	1.5	1.4	2.9	-0.4	1.2	1.7	0.5	1.5	1.2
Delay disc. indifference point, 4s delay	0.7	0.7	1.5	1.2	-0.8	-0.5	-1.2	-0.6	-0.5
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	0.1	-0.1	0.4	-0.1	0.5	0.3
Delay discount exponential model param	0.2	0.2	0.5	-0.2	-0.2	-0.7	0.1	-0.6	-0.3
Delay discount hyperbolic model param	0.2	0.2	0.5	-0.2	-0.3	-0.7	0.1	-0.6	-0.2
Fecal boli incidents, locomotor time 1	1.9	2.1	4.2	0.4	-1.1	-1.6	-0.3	-2.0	-2.1
Change in fecal boli incidents, locomotor task	0.9	0.9	2.3	-1.4	0.9	0.1	1.5	0.2	0.0
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.1	-0.3	-0.2	-0.2	0.3	-0.0	-0.3
Bouts of movement, locomotor time 1	0.6	0.7	1.4	1.2	0.0	0.5	-1.1	0.9	0.6
Total resting periods, locomotor time 1	0.4	0.4	1.0	1.0	0.0	0.4	-0.9	0.7	0.5
Rest time, locomotor task time 1	0.7	0.8	2.3	-0.0	-0.2	-0.9	0.2	-1.2	-1.5
Distance moved, locomotor task time 1	0.3	0.4	1.1	0.2	-0.1	0.4	-0.4	1.0	0.9
Vertical activity count, locomotor time 1	1.2	1.2	3.2	-0.0	0.7	1.1	-0.1	1.5	1.8
Time >=10cm from walls, locomotor time 2	1.8	1.9	3.0	1.0	-1.5	-1.3	-1.0	-1.4	-1.7
Bouts of movement, locomotor time 2	0.4	0.4	1.0	0.9	-0.7	-0.3	-1.0	-0.0	0.1
Total resting periods, locomotor time 2	0.6	0.6	1.1	1.0	-1.0	-0.6	-1.1	-0.5	-0.2
Rest time, locomotor task time 2	0.7	0.8	1.6	0.4	-0.7	-1.1	-0.4	-1.2	-1.1
Distance moved, locomotor task time 2	0.2	0.3	0.5	0.6	-0.4	0.2	-0.7	0.6	0.4
Vertical activity count, locomotor time 2	0.8	0.9	1.6	0.0	0.7	1.2	0.1	1.3	1.3
Weight adjusted by age	0.3	0.4	0.7	-0.6	0.3	0.8	0.2	0.8	0.6
Seeking ratio, delayed vs. immediate footshock	0.8	0.9	1.6	0.5	0.6	1.3	-0.4	1.2	1.3
Locomotion in novel chamber	0.4	0.4	1.0	-0.1	-0.6	-0.7	-0.2	-0.8	-1.0
Locomotion in novel chamber post-restriction	0.1	0.1	0.2	-0.0	-0.1	-0.4	0.2	-0.1	-0.4
Progressive ratio	0.4	0.5	0.7	0.8	-0.8	-0.7	-0.7	-0.7	-0.2
Food seeking constrained by brief footshock	0.7	0.9	2.8	-0.2	0.8	0.8	0.4	1.0	1.7
Seeking ratio, punishment vs. effort	0.4	0.4	0.9	-0.1	0.6	0.8	0.1	0.9	0.8
Run reversals in cocaine runway, females	1.0	0.9	1.8	-0.4	0.9	1.2	0.2	1.3	1.1
Run reversals in cocaine runway, males	0.9	0.9	2.1	-1.4	0.3	-0.6	1.4	-0.6	-0.5
Latency to leave start box in cocaine runway	0.4	0.5	0.9	-0.2	0.9	1.0	0.3	0.8	0.6
Latency to leave start box in cocaine runway, F	0.2	0.2	0.6	0.1	0.5	0.8	-0.1	0.7	0.2
Latency to leave start box in cocaine runway, M	0.2	0.2	0.5	-0.5	0.4	0.0	0.7	0.1	0.4
Cd content in liver	0.2	0.2	0.4	-0.6	0.1	-0.2	0.6	0.4	0.6
Co content in liver	0.2	0.2	0.7	-0.2	0.0	-0.4	0.3	-0.5	-0.8
Cu content in liver	0.8	1.0	1.4	-0.8	1.2	1.0	1.1	1.1	0.8
Fe content in liver	0.1	0.1	0.2	0.3	-0.4	-0.4	-0.3	0.0	-0.2
K content in liver	0.1	0.1	0.2	0.4	-0.3	-0.3	0.0	-0.4	-0.3
Mg content in liver	0.6	0.6	1.5	0.5	-0.4	-0.7	0.1	-1.1	-1.2
Mn content in liver	1.3	1.5	2.9	0.3	-1.2	-1.7	-0.1	-1.6	-1.4
Na content in liver	0.4	0.5	1.6	0.1	0.4	0.6	0.1	0.8	1.3
Rb content in liver	0.1	0.1	0.4	0.4	0.1	0.3	0.2	0.3	-0.6
Se content in liver	4.1	4.9	10.8	0.9	-1.9	-2.4	-0.7	-2.8	-3.3
Sr content in liver	1.0	0.9	1.6	0.3	-1.0	-1.2	-0.7	-1.3	-1.0
Zn content in liver	0.1	0.1	0.3	-0.4	0.4	0.2	0.4	-0.0	-0.6