Rpap3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000053405 0.08 0.07 2.5e-08 0.05 0.06 0.05 0.05 1.5e-06 2.3e-07 1.2e-06 1.2e-06
2 Adipose isoform ratio ENSRNOT00000083926 0.42 0.21 7.6e-04 0.01 0.02 0.03 0.03 1.6e-02 2.9e-03 4.2e-04 3.4e-04
3 Adipose mRNA stability ENSRNOG00000053405 0.04 0.04 1.4e-04 0.02 0.03 0.02 0.02 6.3e-03 2.7e-04 5.3e-03 4.9e-03
4 BLA gene expression ENSRNOG00000053405 0.57 0.21 0.0e+00 0.35 0.12 0.39 0.16 9.0e-20 5.3e-07 3.7e-22 5.6e-09
5 Brain gene expression ENSRNOG00000053405 0.17 0.11 0.0e+00 0.18 0.19 0.18 0.19 8.0e-17 4.6e-17 2.3e-16 4.4e-17
6 Brain mRNA stability ENSRNOG00000053405 0.07 0.05 2.2e-07 0.06 0.07 0.06 0.07 1.2e-06 2.0e-07 6.8e-06 7.6e-07
7 IL isoform ratio ENSRNOT00000111323 0.18 0.14 5.7e-04 0.1 0.12 0.07 0.08 2.7e-03 9.5e-04 7.3e-03 5.3e-03
8 IL intron excision ratio chr7:128813961:128814331 0.17 0.14 8.1e-04 0.1 0.11 0.08 0.09 2.2e-03 1.6e-03 6.3e-03 2.9e-03
9 IL intron excision ratio chr7:128814428:128815307 0.13 0.12 5.4e-03 0.06 0.07 0.06 0.05 1.2e-02 9.2e-03 1.4e-02 2.0e-02
10 LHb gene expression ENSRNOG00000053405 0.15 0.13 4.5e-03 0.07 0.07 0.05 0.07 7.5e-03 7.7e-03 2.8e-02 1.1e-02
11 Liver gene expression ENSRNOG00000053405 0.49 0.15 0.0e+00 0.43 0.45 0.44 0.44 1.6e-52 2.6e-55 3.8e-53 2.6e-53
12 Liver mRNA stability ENSRNOG00000053405 0.08 0.07 1.1e-08 0.05 0.06 0.06 0.05 1.7e-06 1.5e-07 9.5e-07 1.1e-06
13 NAcc gene expression ENSRNOG00000053405 0.22 0.14 2.1e-15 0.17 0.19 0.18 0.18 2.0e-12 7.6e-14 1.3e-13 1.5e-13
14 NAcc intron excision ratio chr7:128838537:128839475 0.04 0.04 5.2e-03 0.02 0.01 -0 0.01 2.1e-02 4.2e-02 5.4e-01 6.3e-02
15 OFC gene expression ENSRNOG00000053405 0.31 0.17 3.2e-06 0.16 0.17 0.16 0.13 1.2e-04 6.8e-05 1.4e-04 5.5e-04
16 PL alternative TSS ENSRNOT00000083926 0.05 0.04 8.6e-04 0.03 0.03 0.02 0.02 4.2e-03 3.6e-03 1.6e-02 2.1e-02
17 PL alternative TSS ENSRNOT00000106326 0.05 0.05 5.4e-04 0.03 0.03 0.02 0.02 3.3e-03 2.9e-03 8.9e-03 9.8e-03
18 PL alternative TSS ENSRNOT00000083926 0.05 0.05 9.7e-04 0.02 0.03 0.01 0.01 1.7e-02 4.5e-03 2.4e-02 2.8e-02
19 PL alternative TSS ENSRNOT00000106326 0.05 0.05 9.2e-04 0.03 0.03 0.02 0.02 5.1e-03 5.2e-03 1.7e-02 1.9e-02
20 PL gene expression ENSRNOG00000053405 0.42 0.21 0.0e+00 0.31 0.3 0.33 0.31 3.7e-24 4.0e-23 1.7e-25 5.9e-24

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
BMI with tail5.016.327.8-4.0-4.5-4.0-4.3-3.7-4.04.0-3.93.9-4.1-4.0-4.0-3.9-3.6-3.94.0-4.04.1-3.4-5.3
BMI without tail0.10.21.6-0.3-0.7-0.4-0.4-0.2-0.40.3-0.20.2-0.4-0.3-0.4-0.3-0.1-0.30.4-0.40.4-0.2-1.3
Body weight7.431.235.0-5.5-5.9-5.6-5.8-5.6-5.65.6-5.45.4-5.8-5.6-5.7-5.4-5.2-5.55.7-5.75.7-5.3-5.8
Epididymis fat weight0.71.62.3-1.3-1.2-1.2-1.2-1.4-1.31.3-1.31.3-1.2-1.3-1.2-1.3-1.5-1.31.2-1.21.2-1.4-1.1
Glucose0.10.10.2-0.3-0.4-0.3-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.2-0.30.3-0.30.3-0.3-0.4
Heart weight0.00.00.3-0.10.1-0.0-0.2-0.2-0.00.10.0-0.00.0-0.2-0.00.0-0.1-0.10.1-0.10.1-0.20.6
Left kidney weight0.51.42.0-1.2-1.1-1.1-1.4-1.4-1.11.1-1.11.1-1.1-1.3-1.1-1.1-1.0-1.21.2-1.21.2-1.3-1.2
Right kidney weight2.98.39.7-2.9-3.1-2.9-3.0-3.1-2.92.9-2.82.8-3.0-2.9-2.9-2.7-2.3-2.93.0-3.03.0-2.9-2.6
Tail length0.00.10.40.40.30.30.40.20.4-0.40.5-0.50.30.40.30.40.40.4-0.30.3-0.3-0.00.7
Length with tail2.17.89.8-2.8-2.8-2.9-2.9-3.1-2.82.8-2.72.7-3.0-2.8-2.9-2.7-2.6-2.82.9-2.92.9-3.0-1.8
Length without tail8.217.819.1-4.3-4.2-4.3-4.4-4.4-4.34.3-4.24.2-4.3-4.3-4.2-4.2-4.1-4.34.3-4.34.3-4.0-3.8
Liver weight, left2.13.45.8-1.8-1.8-1.8-1.7-1.8-1.81.8-1.91.9-1.7-1.7-1.8-1.9-1.9-1.81.8-1.81.7-1.9-2.4
Liver weight, right2.03.35.0-1.8-2.0-1.8-1.8-1.8-1.81.8-1.81.8-1.8-1.7-1.8-1.7-1.5-1.81.8-1.81.8-1.8-2.2
Parametrial fat weight0.81.52.11.21.21.31.41.41.3-1.21.2-1.21.31.21.31.10.51.2-1.41.4-1.41.50.4
Retroperitoneal fat weight0.00.10.10.20.40.30.20.10.3-0.20.2-0.20.30.10.30.20.00.1-0.30.3-0.30.10.3
Intraocular pressure10.514.817.33.93.93.94.24.13.9-3.93.8-3.74.04.03.93.63.23.9-4.04.0-4.03.93.0
Extensor digitorum longus weight6.225.127.3-5.1-4.8-5.1-5.2-5.2-5.15.1-5.15.0-5.0-5.1-5.1-5.0-4.8-5.15.1-5.15.1-5.2-3.5
Soleus weight1.23.43.9-1.9-1.8-1.8-1.8-1.9-1.81.9-1.91.9-1.9-1.9-1.8-1.8-1.9-1.91.8-1.81.8-2.0-1.2
Tibialis anterior weight2.69.110.0-3.0-3.0-3.1-3.1-3.1-3.03.1-3.03.0-3.1-3.1-3.1-3.0-2.9-3.13.1-3.13.1-3.2-2.0
Tibia length6.117.122.3-4.1-4.4-4.1-4.0-4.0-4.14.1-4.14.1-4.0-4.0-4.2-4.2-4.2-4.04.1-4.14.1-4.0-4.7
Number of licking bursts0.30.30.80.60.50.50.50.60.5-0.50.6-0.60.50.60.50.60.60.6-0.50.5-0.50.60.9
Food consumed during 24 hour testing period1.31.62.3-1.3-1.2-1.2-1.2-1.3-1.21.2-1.21.2-1.2-1.3-1.2-1.3-1.2-1.21.2-1.21.2-1.3-1.5
Times rat made contact with spout0.10.10.2-0.4-0.3-0.3-0.3-0.3-0.30.4-0.30.3-0.3-0.4-0.3-0.3-0.4-0.40.3-0.30.3-0.3-0.3
Mean time between licks in bursts0.50.70.90.90.80.80.90.90.8-0.80.8-0.80.90.90.80.80.70.9-0.80.8-0.81.00.6
Mean num. licks in bursts0.10.10.6-0.3-0.2-0.2-0.3-0.3-0.20.3-0.30.3-0.2-0.4-0.2-0.3-0.3-0.30.2-0.20.2-0.3-0.8
Std. dev. time between licks in bursts1.01.21.51.11.11.11.21.21.1-1.11.0-1.01.21.21.11.01.01.1-1.11.1-1.11.20.7
Water consumed over 24 hours0.20.20.3-0.5-0.5-0.4-0.5-0.5-0.40.5-0.50.5-0.4-0.5-0.4-0.5-0.5-0.50.4-0.40.4-0.5-0.4
Indifference point 0 sec1.42.22.91.51.21.51.51.51.5-1.51.5-1.51.51.51.51.61.51.5-1.51.5-1.51.71.0
Indifference point AUC0.10.11.30.30.50.30.20.20.3-0.30.3-0.30.30.20.30.30.20.3-0.30.3-0.30.31.1
Indifference point function ln k3.34.65.8-2.1-2.4-2.2-2.2-2.1-2.22.1-2.02.0-2.2-2.1-2.2-2.0-2.0-2.12.2-2.22.2-2.0-2.4
Indifference point function log k3.34.65.8-2.1-2.4-2.2-2.2-2.1-2.22.1-2.02.0-2.2-2.1-2.2-2.0-2.0-2.12.2-2.22.2-2.0-2.4
Delay discounting total patch changes 0 sec1.32.22.61.51.21.51.51.51.5-1.51.5-1.51.51.51.51.51.41.5-1.51.5-1.51.61.0
Delay discounting total patch changes 12 sec1.11.52.11.21.31.21.31.11.2-1.21.1-1.11.31.21.21.11.01.2-1.31.3-1.31.41.4
Delay discounting total patch changes 18 sec3.14.16.92.02.12.01.91.82.0-2.02.0-1.92.02.02.02.01.92.0-2.02.0-2.02.02.6
Delay discounting total patch changes 24 sec1.01.31.81.21.11.11.21.01.1-1.21.1-1.11.11.21.11.11.01.2-1.21.2-1.21.11.4
Delay discounting total patch changes 6 sec2.33.65.41.91.91.91.81.71.9-1.91.8-1.81.91.91.91.91.91.9-1.91.9-1.91.92.3
Delay discounting time to switch 0 sec3.24.95.52.22.32.22.32.12.2-2.22.2-2.22.32.22.22.22.22.2-2.22.2-2.22.12.3
Delay discounting water rate 0 sec4.77.58.3-2.8-2.8-2.7-2.7-2.7-2.72.8-2.82.8-2.8-2.8-2.7-2.8-2.9-2.82.7-2.72.7-2.5-2.6
Delay discounting water rate 12 sec3.75.66.7-2.4-2.3-2.4-2.3-2.4-2.42.4-2.32.3-2.5-2.4-2.4-2.4-2.6-2.42.4-2.42.4-2.5-1.7
Delay discounting water rate 18 sec0.81.11.6-1.0-1.0-1.0-1.0-1.1-1.01.1-1.11.1-1.1-1.1-1.1-1.1-1.3-1.11.0-1.01.0-1.1-0.8
Delay discounting water rate 24 sec3.65.07.5-2.2-2.3-2.2-2.1-2.1-2.22.3-2.32.3-2.1-2.2-2.2-2.4-2.7-2.22.2-2.22.1-2.1-2.2
Delay discounting water rate 6 sec4.97.19.6-2.7-2.7-2.6-2.5-2.9-2.62.7-2.72.7-2.7-2.7-2.6-2.7-3.1-2.72.6-2.62.6-2.9-1.8
Locomotor activity0.91.42.31.21.01.21.31.31.2-1.21.2-1.21.21.31.21.21.21.2-1.21.2-1.21.50.6
Locomotor testing distance2.74.55.92.11.92.12.22.22.1-2.22.1-2.12.12.22.12.22.32.1-2.12.1-2.12.41.3
Locomotor testing rearing2.64.15.52.11.82.02.01.92.0-2.12.1-2.12.12.12.02.22.32.1-2.02.0-2.02.11.6
Light reinforcement 12.85.26.12.32.22.32.22.22.3-2.32.3-2.32.52.32.22.22.22.3-2.32.3-2.32.12.4
Light reinforcement 20.91.21.41.21.11.11.01.11.1-1.11.2-1.21.21.11.11.11.11.2-1.11.1-1.11.11.0
Reaction time number correct0.50.82.0-0.8-0.9-0.8-0.9-0.8-0.80.9-0.90.9-0.9-0.9-0.8-0.9-1.0-0.80.8-0.80.8-0.6-1.4
Reaction time mean minus median9.212.013.23.43.53.53.63.53.5-3.53.5-3.53.53.53.53.53.63.5-3.53.5-3.53.62.6
Reaction time mean minus median AUC6.78.69.92.92.93.03.12.92.9-3.02.9-2.93.13.03.03.03.12.9-3.03.0-3.03.11.9
Reaction time num false alarms1.92.63.11.61.61.61.51.81.6-1.61.7-1.71.61.51.61.61.61.6-1.61.6-1.61.51.7
Reaction time num false alarms AUC3.14.45.02.12.12.12.12.22.1-2.12.1-2.12.02.02.12.12.22.1-2.12.1-2.12.01.8
Reaction time trials correct on left0.50.82.0-0.8-0.9-0.8-0.9-0.8-0.80.9-0.90.9-0.9-0.9-0.8-0.9-1.0-0.80.8-0.80.8-0.6-1.4
Reaction time trials on left0.40.51.6-0.7-0.7-0.7-0.7-0.6-0.70.7-0.70.7-0.7-0.7-0.7-0.8-0.8-0.70.6-0.60.6-0.4-1.3
Reaction time mean0.71.01.51.01.01.01.20.81.0-1.00.9-0.91.21.11.00.90.91.0-1.01.0-1.01.00.4
Reaction time mean AUC0.40.50.90.70.80.80.90.60.7-0.70.6-0.61.00.80.80.70.60.7-0.80.8-0.80.80.1
Median of all reaction times0.00.00.1-0.00.0-0.00.2-0.3-0.00.0-0.10.10.20.10.0-0.1-0.20.0-0.00.0-0.0-0.0-0.1
Reaction time omissions9.612.914.53.53.83.63.63.53.6-3.63.5-3.53.83.63.73.63.63.6-3.73.7-3.73.53.4
Reaction time false alarm rate2.43.43.91.81.81.81.81.91.8-1.81.9-1.91.81.81.81.91.91.8-1.81.8-1.81.62.0
Reaction time premature initiation rate3.74.99.72.22.52.22.21.92.2-2.22.1-2.12.42.12.32.11.92.1-2.32.3-2.31.73.1
Reaction time premature initiations2.13.04.51.71.91.81.71.51.8-1.71.6-1.61.91.61.81.61.41.7-1.81.8-1.81.42.1
Std. dev. reaction times6.89.310.33.03.03.13.23.03.0-3.13.0-3.03.23.13.13.13.23.1-3.13.1-3.13.22.1
Reaction time trials completed0.40.51.6-0.7-0.7-0.7-0.7-0.6-0.70.7-0.70.7-0.7-0.7-0.7-0.8-0.8-0.70.6-0.60.6-0.4-1.3
Reaction time trials AUC0.81.12.7-1.0-1.1-1.0-1.1-1.0-1.01.0-1.01.0-1.1-1.1-1.0-1.1-1.1-1.01.0-1.01.0-0.8-1.6
Social response proportion0.70.81.40.90.80.80.80.80.8-0.90.9-0.90.70.90.81.01.10.9-0.80.8-0.81.20.7
Social responses9.111.813.83.43.43.43.33.43.4-3.43.4-3.53.23.43.43.53.73.4-3.43.4-3.43.63.6
Social time0.91.22.31.10.81.11.11.11.0-1.11.2-1.21.01.21.01.21.51.2-1.01.0-1.01.3-0.2
Conditioned locomotion0.00.00.10.2-0.00.10.10.20.1-0.20.2-0.20.10.20.10.20.10.2-0.10.1-0.10.30.3
Cocaine response after cond. corrected0.10.10.2-0.3-0.1-0.2-0.4-0.2-0.20.3-0.20.2-0.2-0.4-0.2-0.2-0.1-0.30.2-0.20.2-0.3-0.4
Cocaine response after cond. not corrected0.70.81.10.81.10.90.80.90.9-0.90.9-0.90.90.80.90.91.10.8-0.90.9-0.90.90.8
Cocaine response before conditioning6.98.49.22.93.02.93.02.92.9-2.92.9-2.82.93.02.92.82.83.0-2.92.9-2.92.92.7
Saline control response0.10.10.20.40.50.40.40.20.4-0.40.4-0.30.50.50.40.30.30.4-0.40.4-0.40.20.2
Condit. Reinf. active minus inactive responses0.00.00.30.10.10.10.1-0.00.1-0.10.1-0.10.10.10.10.10.10.1-0.10.1-0.10.00.5
Condit. Reinf. active-inactive response ratio0.20.30.90.50.50.50.30.40.5-0.50.6-0.60.40.40.40.60.60.5-0.40.4-0.40.40.9
Condit. Reinf. active responses0.20.31.20.60.60.50.50.40.5-0.50.6-0.60.60.50.50.50.40.5-0.50.5-0.50.41.1
Condit. Reinf. inactive responses1.01.21.71.11.11.11.21.01.1-1.11.1-1.11.21.11.11.10.91.1-1.11.1-1.11.01.3
Condit. Reinf. lever presses0.00.00.00.10.20.10.20.00.1-0.10.1-0.10.20.10.10.0-0.20.1-0.10.1-0.10.00.1
Condit. Reinf. lever reinforcers received0.50.71.90.90.90.80.80.70.8-0.80.8-0.90.90.80.80.80.70.8-0.80.8-0.80.71.4
Pavlov. Cond. lever latency0.00.00.2-0.2-0.2-0.2-0.3-0.2-0.20.2-0.20.1-0.4-0.2-0.2-0.10.2-0.20.2-0.20.2-0.20.2
Pavlov. Cond. magazine entry latency0.20.30.7-0.5-0.6-0.5-0.5-0.5-0.50.5-0.50.5-0.5-0.4-0.5-0.5-0.4-0.40.5-0.50.5-0.5-0.8
Pavlov. Cond. change in total contacts0.81.12.0-1.0-1.1-1.0-1.0-1.1-1.01.0-1.01.0-0.8-0.9-1.0-1.1-1.2-0.91.0-1.01.0-1.1-1.4
Pavlov. Cond. index score0.10.20.5-0.3-0.4-0.4-0.3-0.4-0.40.4-0.40.4-0.2-0.3-0.4-0.4-0.6-0.30.4-0.40.4-0.4-0.7
Pavlov. Cond. latency score0.20.20.8-0.4-0.5-0.5-0.4-0.5-0.50.5-0.50.5-0.3-0.4-0.5-0.5-0.6-0.40.5-0.50.5-0.5-0.9
Pavlov. Cond. lever contacts0.20.30.60.60.60.60.70.50.6-0.60.6-0.50.80.60.60.50.10.6-0.60.6-0.60.50.1
Pavlov. Cond. magazine entry number1.11.31.61.11.31.21.11.21.2-1.11.1-1.11.11.11.21.21.11.1-1.21.2-1.21.21.3
Pavlov. Cond. intertrial magazine entries2.33.04.01.72.01.81.81.81.8-1.71.6-1.61.71.61.81.71.51.6-1.81.8-1.81.91.9
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.6-0.6-0.6-0.5-0.7-0.60.6-0.60.6-0.4-0.5-0.6-0.7-0.8-0.50.6-0.60.6-0.7-0.8
Pavlov. Cond. response bias0.10.20.40.40.40.40.50.30.4-0.40.4-0.40.60.50.40.30.10.5-0.40.4-0.40.30.2
Conditioned reinforcement - actives1.51.52.31.21.31.21.21.51.2-1.21.1-1.11.31.21.21.11.01.2-1.21.2-1.21.21.3
Conditioned reinforcement - inactives1.01.22.11.01.21.11.01.21.1-1.11.0-1.01.21.01.11.11.11.0-1.11.1-1.10.91.4
Conditioned locomotion0.30.31.00.50.60.50.60.70.5-0.50.5-0.50.70.60.50.40.30.5-0.60.6-0.60.41.0
Intermittent access intake day 1-15 change0.90.91.41.00.91.00.90.91.0-0.91.0-1.01.10.81.00.90.50.9-1.01.0-1.00.61.2
Intermittent access intake escalation0.50.51.30.70.70.80.60.60.8-0.70.8-0.80.90.60.80.70.30.7-0.80.8-0.80.31.1
Intermittent access intake escalation 20.80.82.00.81.00.90.80.70.9-0.90.8-0.81.10.80.90.80.60.8-0.90.9-0.90.51.4
Intermitt. access day 1 inactive lever presses3.53.75.91.92.01.92.02.11.9-1.91.8-1.81.91.91.91.91.81.9-1.91.9-1.91.92.4
Intermitt. access day 15 inactive lever presses1.01.11.71.11.01.00.91.01.0-1.01.1-1.11.01.01.01.11.31.0-1.01.0-1.01.31.0
Intermitt. access escalation Index0.30.30.70.50.40.50.70.70.6-0.50.4-0.40.50.60.60.50.40.5-0.60.6-0.60.8-0.3
Intermittent access day 1 total infusions1.51.72.31.31.11.31.21.41.3-1.31.3-1.31.31.31.31.31.51.3-1.31.3-1.31.40.7
Intermittent access day 15 total infusions2.42.73.11.71.51.61.51.61.7-1.61.7-1.71.81.61.61.71.71.6-1.61.6-1.61.41.7
Intermittent access terminal intake (last 3 days)2.52.73.21.71.51.71.51.61.7-1.71.7-1.71.81.61.71.71.71.7-1.61.6-1.61.51.6
Intermittent access total infusions2.42.73.11.61.51.61.61.61.7-1.61.6-1.61.81.61.61.61.61.6-1.61.6-1.61.41.7
Intermittent access day 1 locomotion1.11.21.71.11.01.01.01.31.0-1.11.1-1.11.11.11.01.11.11.1-1.01.0-1.01.10.9
Intermittent access day 15 total locomotion1.01.12.61.01.01.00.91.01.0-1.01.0-1.01.11.01.01.11.21.1-1.01.0-1.00.91.6
Intermittent access total locomotion2.42.85.31.71.71.61.61.61.6-1.61.6-1.61.81.71.61.51.51.7-1.71.7-1.71.22.3
Intermittent access standard deviation0.60.71.00.80.60.80.70.80.8-0.80.9-0.90.90.80.80.91.00.8-0.80.8-0.80.60.6
Cocaine induced anxiety1.21.31.9-1.2-1.0-1.2-1.2-0.9-1.21.2-1.21.2-1.1-1.2-1.2-1.2-1.4-1.21.1-1.11.1-1.0-1.2
Post-drug Anxiety4.44.96.3-2.2-2.1-2.2-2.1-2.0-2.22.2-2.32.3-2.1-2.2-2.2-2.3-2.5-2.22.2-2.22.2-2.2-2.3
Baseline Anxiety1.11.22.5-1.1-1.2-1.1-1.0-1.1-1.11.0-1.11.1-1.1-1.0-1.0-1.0-0.9-1.01.1-1.11.1-1.1-1.6
Lifetime Intake1.82.02.41.41.41.41.41.41.4-1.41.4-1.41.61.41.41.41.41.4-1.41.4-1.41.31.5
Incentive Sensitization - Responses0.10.10.1-0.2-0.3-0.2-0.3-0.1-0.20.2-0.10.1-0.3-0.2-0.2-0.10.3-0.20.3-0.30.30.1-0.4
Incentive Sensitization - Breakpoint0.00.00.3-0.0-0.1-0.1-0.20.1-0.10.00.0-0.0-0.10.0-0.10.10.5-0.00.1-0.10.10.4-0.3
Progressive ratio test 1 active lever presses3.33.54.11.91.91.91.92.01.9-1.91.8-1.82.01.91.91.81.81.9-1.91.9-1.91.71.8
Progressive ratio test 1 breakpoint3.13.23.81.81.71.81.82.01.8-1.81.7-1.71.91.81.81.81.81.8-1.81.8-1.81.81.6
Progressive ratio test 1 inactive lever presses2.52.63.81.61.71.61.41.91.6-1.61.6-1.61.61.51.61.71.71.6-1.61.5-1.51.91.6
Progressive ratio test 2 active lever presses1.71.83.11.31.31.31.31.31.3-1.31.3-1.31.41.41.31.41.51.4-1.31.3-1.31.21.8
Progressive ratio test 2 breakpoint2.32.53.71.61.51.61.51.61.6-1.61.6-1.61.71.61.61.61.71.6-1.61.6-1.61.41.9
Progressive ratio test 2 inactive lever presses2.93.44.21.81.71.81.82.11.8-1.81.8-1.91.81.81.81.91.91.8-1.81.8-1.82.01.8
Total sessions with >9 infusions0.40.40.70.70.50.60.60.80.6-0.60.7-0.70.70.70.60.70.70.7-0.60.6-0.60.50.3
Short access day 1 total inactive lever presses0.70.71.10.91.00.90.91.00.9-0.80.8-0.81.00.80.90.70.50.8-0.90.9-0.90.80.9
Short access day 10 total inactive lever presses0.40.42.40.50.80.50.60.30.6-0.50.5-0.50.70.50.50.50.40.5-0.60.6-0.60.51.6
Short access day 1 total infusions0.00.00.3-0.1-0.2-0.2-0.30.0-0.20.1-0.10.1-0.2-0.1-0.2-0.00.2-0.10.2-0.20.20.0-0.5
Short access day 10 total infusions0.60.71.30.80.70.80.70.80.8-0.80.9-0.90.90.70.80.80.80.8-0.80.8-0.80.51.1
Short access total infusions0.10.10.20.40.30.40.30.40.4-0.40.4-0.40.50.40.40.40.50.4-0.40.4-0.40.40.3
Short access day 1 locomotion0.00.10.40.1-0.2-0.0-0.10.4-0.0-0.10.2-0.2-0.10.1-0.10.20.60.10.1-0.10.10.3-0.4
Short access day 10 total locomotion0.20.22.30.40.40.30.40.20.4-0.40.4-0.40.40.40.30.30.20.4-0.30.3-0.3-0.11.5
Short access total locomotion0.20.20.80.40.40.40.30.40.4-0.40.4-0.40.50.40.30.40.30.4-0.40.4-0.30.20.9
Compulsive drug intake0.60.62.1-0.7-0.8-0.7-0.7-0.6-0.70.7-0.70.7-0.8-0.7-0.7-0.7-0.8-0.70.7-0.70.7-0.5-1.5
One hour access (0.3 mA shock)0.20.20.70.40.50.40.20.40.4-0.40.5-0.50.50.40.40.50.80.4-0.40.4-0.40.50.6
One hour access (shock baseline)0.00.00.30.10.10.1-0.10.00.1-0.10.1-0.10.10.10.10.20.50.1-0.10.0-0.00.20.3
Number of responses in last shaping day0.40.40.9-0.5-0.7-0.6-0.8-0.9-0.60.6-0.40.4-0.6-0.6-0.7-0.5-0.4-0.60.7-0.70.7-0.7-0.1
Context. condit. distance diff. score0.40.50.8-0.7-0.8-0.7-0.7-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.70.7-0.70.7-0.7-0.9
Locomotion velocity, session 10.60.62.30.80.70.80.70.60.8-0.80.8-0.90.70.70.70.80.70.7-0.70.7-0.70.61.5
Locomotion distance, session 12.73.54.01.91.81.91.81.81.9-1.91.9-1.91.91.81.92.02.01.9-1.91.9-1.91.81.5
Locomotion velocity, session 20.20.20.40.40.40.50.50.40.5-0.40.4-0.40.50.40.50.40.20.4-0.50.5-0.50.40.6
Locomotion distance, session 22.13.03.31.71.81.81.71.71.8-1.71.7-1.71.71.61.81.71.51.7-1.81.8-1.81.71.7
Locomotion velocity, session 33.03.53.91.91.91.91.82.01.9-1.91.9-1.91.81.81.91.91.71.8-1.91.9-1.92.01.7
Locomotion distance, session 35.15.55.92.42.42.42.42.42.4-2.42.4-2.42.42.32.42.32.02.4-2.42.4-2.42.42.1
Stereotopy head waving bouts, day 30.80.91.1-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.0-1.0-0.8
Stereotopy head waving duration, day 30.20.30.4-0.5-0.6-0.5-0.5-0.6-0.50.5-0.50.6-0.5-0.5-0.5-0.6-0.6-0.50.5-0.50.5-0.6-0.3
Locomotion velocity, session 70.00.00.10.20.20.10.20.40.2-0.10.2-0.20.10.20.10.2-0.10.2-0.10.1-0.10.4-0.1
Locomotion distance, session 71.21.62.01.31.21.21.21.41.2-1.31.3-1.31.21.31.21.31.21.3-1.21.2-1.21.40.9
Stereotopy head waving bouts, day 71.11.21.5-1.1-1.1-1.1-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.2-1.2-1.11.1-1.11.1-1.1-0.9
Stereotopy head waving duration, day 71.92.33.0-1.5-1.5-1.5-1.5-1.5-1.51.6-1.61.6-1.4-1.6-1.5-1.6-1.7-1.61.5-1.51.5-1.5-1.1
Locomotion velocity, session 80.20.30.7-0.5-0.4-0.5-0.5-0.5-0.40.5-0.50.5-0.5-0.6-0.5-0.5-0.8-0.60.5-0.50.5-0.5-0.4
Locomotion distance, session 80.81.11.31.11.21.11.11.01.1-1.11.0-1.01.11.01.11.00.81.0-1.11.1-1.11.00.8
Degree of sensitization distance0.70.80.9-0.9-0.9-0.9-0.9-0.8-0.90.9-0.80.8-1.0-0.8-0.9-0.8-0.7-0.90.9-0.90.9-0.8-0.8
Degree of sensitization stereotypy0.70.71.2-0.9-0.8-0.9-0.8-0.8-0.80.9-0.90.9-0.8-0.9-0.8-0.9-1.1-0.90.8-0.80.8-0.8-0.5
Condit. Reinf. active minus inactive responses0.10.10.30.30.40.30.30.30.3-0.30.4-0.40.30.30.30.30.20.3-0.30.3-0.30.30.5
Condit. Reinf. active-inactive response ratio0.10.10.1-0.3-0.3-0.3-0.4-0.4-0.30.3-0.30.3-0.3-0.4-0.3-0.3-0.3-0.40.3-0.30.3-0.4-0.4
Condit. Reinf. active responses0.70.82.00.90.90.90.80.80.9-0.90.9-0.90.80.80.90.90.80.9-0.90.9-0.80.81.4
Condit. Reinf. inactive responses3.13.76.51.91.91.91.81.71.9-1.92.0-2.01.81.91.92.01.91.9-1.91.9-1.81.72.5
Incentive salience index mean0.00.00.1-0.1-0.0-0.1-0.1-0.2-0.10.1-0.10.1-0.1-0.2-0.1-0.1-0.3-0.10.1-0.10.1-0.20.3
Condit. Reinf. lever presses0.20.20.4-0.5-0.4-0.5-0.4-0.6-0.50.5-0.50.5-0.5-0.4-0.5-0.5-0.6-0.40.5-0.50.5-0.6-0.0
Time in familiar zone, hab. session 10.10.10.20.40.30.40.30.40.4-0.40.4-0.40.40.30.40.40.40.3-0.40.4-0.40.40.1
Time in novel zone, hab. session 10.00.00.1-0.2-0.2-0.3-0.1-0.2-0.30.2-0.20.2-0.2-0.1-0.3-0.3-0.2-0.20.2-0.20.2-0.20.0
Total zone transitions, hab. session 10.30.40.80.60.70.60.70.50.6-0.60.6-0.60.60.60.60.50.30.6-0.60.6-0.60.50.9
Total locomotion distance, hab. session 10.00.00.10.20.30.20.20.10.2-0.20.2-0.10.30.20.20.1-0.20.2-0.20.2-0.20.10.3
Locomotion velocity, hab. session 10.00.00.10.10.20.10.10.00.1-0.10.1-0.10.20.10.1-0.0-0.30.1-0.10.1-0.10.00.2
Time in familiar zone, hab. session 20.00.00.1-0.1-0.1-0.1-0.2-0.3-0.10.1-0.10.1-0.1-0.1-0.2-0.1-0.1-0.10.2-0.20.2-0.30.1
Time in novel zone, hab. session 20.00.00.00.10.10.10.20.20.1-0.10.1-0.10.10.10.10.10.10.1-0.10.1-0.10.20.2
Total zone transitions, hab. session 20.10.10.10.30.30.30.20.20.3-0.30.3-0.30.20.20.30.30.20.2-0.30.3-0.30.20.3
Total locomotion distance, hab. session 20.10.20.30.40.40.40.40.50.4-0.40.5-0.50.40.40.40.50.40.4-0.40.4-0.40.50.2
Locomotion velocity, hab. session 20.00.00.10.20.20.20.10.30.2-0.20.2-0.20.20.10.20.20.10.2-0.20.2-0.20.3-0.1
Novel to familiar place preference ratio0.91.01.4-0.9-1.1-1.0-1.0-0.9-1.00.9-0.90.9-1.0-0.8-1.0-0.9-0.6-0.91.0-1.01.0-0.9-1.2
Novelty place preference0.50.50.8-0.6-0.8-0.7-0.7-0.6-0.70.7-0.70.7-0.7-0.6-0.8-0.7-0.3-0.60.7-0.70.7-0.6-0.9
Time in novel zone, NPP test0.30.30.6-0.5-0.7-0.6-0.5-0.5-0.60.5-0.50.5-0.6-0.4-0.6-0.5-0.2-0.40.6-0.60.6-0.5-0.8
Total zone transitions, NPP test0.91.31.51.11.21.21.11.11.2-1.11.1-1.11.21.11.21.11.01.1-1.21.2-1.21.11.0
Total locomotion distance, NPP test2.53.43.71.91.91.91.91.81.9-1.91.9-1.91.91.81.91.81.61.9-1.91.9-1.91.81.7
Locomotion velocity, NPP test1.31.92.11.41.41.41.41.41.4-1.41.4-1.41.41.41.41.41.21.4-1.41.4-1.41.41.2
Pavlov. Cond. lever latency0.00.00.1-0.2-0.2-0.2-0.2-0.3-0.20.2-0.10.1-0.2-0.3-0.2-0.1-0.1-0.20.2-0.20.2-0.30.3
Pavlov. Cond. magazine entry latency0.00.00.40.10.20.10.10.30.1-0.10.0-0.00.00.10.10.00.10.1-0.10.1-0.10.3-0.7
Pavlov. Cond. change in total contacts0.00.00.00.00.0-0.00.0-0.0-0.00.0-0.00.0-0.00.0-0.0-0.00.00.00.0-0.00.0-0.0-0.1
Pavlov. Cond. index score0.10.10.8-0.3-0.2-0.3-0.3-0.1-0.30.3-0.40.4-0.3-0.3-0.3-0.4-0.3-0.30.3-0.30.3-0.1-0.9
Pavlov. Cond. latency score0.00.10.6-0.2-0.1-0.2-0.10.0-0.20.2-0.20.3-0.2-0.1-0.2-0.3-0.2-0.20.2-0.20.2-0.0-0.8
Pavlov. Cond. lever contacts0.30.40.50.60.70.60.70.70.6-0.60.6-0.60.60.70.60.50.50.7-0.60.6-0.60.70.3
Pavlov. Cond. magazine entry number0.00.00.4-0.0-0.2-0.1-0.1-0.3-0.00.00.0-0.0-0.0-0.1-0.10.0-0.0-0.00.1-0.10.1-0.30.6
Pavlov. Cond. intertrial magazine entries0.50.61.10.80.60.80.70.60.8-0.80.8-0.80.80.70.80.80.80.8-0.80.8-0.70.61.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.6-0.7-0.6-0.7-0.6-0.5-0.70.7-0.80.8-0.7-0.7-0.7-0.8-0.7-0.70.7-0.70.7-0.5-1.3
Pavlov. Cond. response bias0.10.10.20.20.40.30.30.50.2-0.20.2-0.20.30.30.30.20.20.3-0.30.3-0.30.5-0.5
Bone: apparent density7.612.615.8-3.5-3.6-3.6-3.6-3.5-3.63.5-3.53.5-3.5-3.4-3.6-3.5-3.3-3.43.6-3.63.6-3.5-4.0
Bone surface10.218.018.3-4.2-4.2-4.3-4.3-4.3-4.34.2-4.24.2-4.2-4.2-4.3-4.3-4.2-4.24.3-4.34.3-4.2-4.2
Bone volume6.611.212.5-3.3-3.4-3.4-3.4-3.3-3.43.3-3.33.3-3.3-3.3-3.4-3.3-3.2-3.33.4-3.43.4-3.3-3.5
Bone: connectivity density5.89.111.1-3.0-3.0-3.0-3.1-3.0-3.03.0-3.03.0-3.0-3.0-3.0-3.0-2.8-3.03.0-3.03.0-3.0-3.3
Bone: cortical apparent density0.50.70.70.80.80.80.80.80.8-0.80.8-0.80.80.80.80.80.80.8-0.80.8-0.80.70.8
Bone: cortical area10.015.118.2-3.9-4.1-3.9-3.9-3.8-3.93.9-3.93.9-3.9-3.8-3.9-3.9-3.7-3.83.9-3.93.9-3.8-4.3
Bone: cortical porosity2.42.63.31.61.71.61.61.81.6-1.61.6-1.61.51.71.61.61.71.7-1.61.6-1.61.81.4
Bone: cortical porosity2.83.03.81.71.91.71.81.91.7-1.71.6-1.61.71.81.71.61.61.7-1.71.7-1.71.91.5
Bone: cortical thickness4.16.99.5-2.6-2.7-2.6-2.6-2.5-2.62.6-2.62.6-2.6-2.5-2.6-2.6-2.5-2.62.6-2.62.6-2.5-3.1
Bone: cortical thickness0.20.31.1-0.5-0.6-0.5-0.6-0.4-0.50.5-0.40.4-0.6-0.5-0.5-0.4-0.1-0.40.5-0.50.5-0.4-1.0
Bone: cortical tissue density0.60.81.00.90.90.90.90.90.9-0.90.9-0.91.00.90.90.90.90.9-0.90.9-0.90.81.0
Bone: elastic displacement4.95.66.32.42.42.42.52.42.4-2.42.3-2.32.52.42.42.32.12.4-2.42.4-2.42.42.1
Bone: elastic work0.10.10.20.30.30.30.40.30.3-0.30.2-0.20.40.40.30.20.20.3-0.30.3-0.30.30.2
Bone: endosteal estimation7.516.216.7-4.0-4.0-4.1-4.0-4.1-4.14.1-4.04.0-4.0-4.0-4.1-4.0-4.0-4.14.1-4.14.1-4.0-3.4
Bone: endosteal perimeter6.914.114.6-3.8-3.8-3.8-3.8-3.8-3.83.8-3.83.8-3.8-3.7-3.8-3.7-3.7-3.83.8-3.83.8-3.8-3.4
Bone: final force10.016.417.4-4.1-4.2-4.1-4.1-4.0-4.14.0-4.04.0-4.1-4.0-4.1-4.0-3.8-4.04.1-4.14.1-4.1-4.2
Bone: final moment10.116.617.7-4.1-4.2-4.1-4.1-4.1-4.14.1-4.14.1-4.1-4.0-4.1-4.1-3.9-4.04.1-4.14.1-4.1-4.2
Bone: marrow area7.616.316.8-4.1-4.0-4.1-4.1-4.1-4.14.1-4.14.1-4.1-4.1-4.1-4.0-4.1-4.14.1-4.14.1-4.1-3.4
Bone: maximum diameter4.88.89.6-3.0-3.1-3.0-3.0-2.8-3.03.0-3.03.0-3.1-2.9-3.0-2.9-2.7-3.03.0-3.03.0-2.8-3.1
Bone: maximum force12.521.822.9-4.7-4.8-4.7-4.7-4.7-4.74.7-4.74.7-4.7-4.6-4.7-4.7-4.4-4.64.7-4.74.7-4.7-4.6
Bone: maximum moment12.521.722.8-4.7-4.8-4.7-4.7-4.7-4.74.7-4.74.7-4.7-4.6-4.7-4.6-4.4-4.64.7-4.74.7-4.7-4.6
Bone: minimum diameter7.814.415.7-3.8-4.0-3.8-3.8-3.8-3.83.8-3.83.8-3.8-3.7-3.8-3.8-3.6-3.73.8-3.83.8-3.8-3.8
Bone: periosteal estimation12.024.525.7-5.0-5.1-5.0-4.9-4.9-5.05.0-4.94.9-5.0-4.9-5.0-4.9-4.8-4.95.0-5.05.0-4.9-4.9
Bone: periosteal perimeter11.018.318.8-4.3-4.3-4.3-4.3-4.2-4.34.3-4.34.3-4.3-4.3-4.3-4.3-4.2-4.34.3-4.34.3-4.2-4.1
Bone: post-yield work8.411.412.1-3.5-3.2-3.4-3.5-3.5-3.53.4-3.53.5-3.5-3.4-3.4-3.4-3.2-3.53.4-3.43.4-3.4-2.5
Bone: stiffness15.424.325.7-4.9-5.1-5.0-5.0-4.8-5.04.9-4.94.9-5.1-4.9-5.0-4.9-4.7-4.95.0-5.05.0-4.8-5.0
Bone: tissue strength0.30.30.5-0.5-0.5-0.6-0.5-0.6-0.60.6-0.60.6-0.4-0.5-0.6-0.6-0.7-0.50.5-0.50.5-0.6-0.4
Bone: trabecular number4.16.48.3-2.5-2.5-2.5-2.6-2.5-2.62.5-2.52.5-2.5-2.5-2.5-2.5-2.4-2.52.5-2.52.5-2.5-2.9
Bone: trabecular spacing1.11.41.81.21.11.21.21.21.2-1.21.1-1.11.11.21.21.21.21.1-1.21.2-1.21.21.4
Bone: trabecular thickness0.40.40.60.70.60.70.60.60.7-0.70.7-0.70.70.70.70.70.80.7-0.70.7-0.60.60.2
Bone: trabecular tissue density0.10.20.40.40.40.40.40.30.4-0.40.4-0.40.50.40.40.30.30.4-0.40.4-0.40.30.6
Breakpoint value in progressive ratio session0.20.20.3-0.5-0.2-0.4-0.4-0.3-0.40.5-0.60.6-0.2-0.4-0.4-0.5-0.5-0.50.4-0.40.4-0.4-0.6
Distance traveled before self-admin1.11.21.51.11.01.01.11.21.1-1.11.0-1.01.21.11.01.11.21.1-1.11.1-1.11.01.0
Distance traveled after self-admin0.00.00.20.10.30.20.30.30.2-0.1-0.00.00.40.20.2-0.1-0.10.1-0.30.3-0.3-0.10.2
Delta time in closed arm before/after self-admin0.10.11.1-0.3-0.3-0.3-0.4-0.2-0.30.3-0.30.3-0.3-0.4-0.3-0.3-0.3-0.30.3-0.30.3-0.0-1.1
Delta time in open arm before/after self-admin3.93.78.71.92.01.91.91.51.9-1.91.8-1.81.91.91.91.91.91.9-1.91.9-1.91.52.9
Diff in mean of infusions in LGA sessions1.01.11.5-1.1-1.0-1.1-1.2-1.1-1.11.0-1.01.0-1.1-1.1-1.1-1.0-0.6-1.11.1-1.11.1-0.8-1.0
Extinction: sum of active levers before priming0.50.60.7-0.8-0.6-0.8-0.9-0.6-0.80.8-0.80.8-0.7-0.7-0.8-0.7-0.6-0.80.8-0.80.8-0.8-0.5
Active lever presses in extinction session 60.40.40.7-0.6-0.6-0.6-0.7-0.6-0.60.6-0.50.5-0.6-0.7-0.6-0.5-0.5-0.60.6-0.60.6-0.9-0.1
Delta distance traveled before/after self-admin0.20.20.6-0.5-0.4-0.4-0.4-0.4-0.40.5-0.50.6-0.4-0.5-0.4-0.6-0.8-0.50.4-0.40.4-0.5-0.6
Delta ambulatory time before/after self-admin0.10.20.6-0.4-0.3-0.3-0.3-0.3-0.30.4-0.40.4-0.3-0.4-0.3-0.5-0.8-0.40.3-0.30.3-0.5-0.3
Time in closed arm before self-admin0.80.91.2-0.9-1.1-1.0-1.1-0.8-1.01.0-0.90.9-1.1-1.0-1.1-0.9-0.8-0.91.0-1.11.1-1.1-0.3
Time in closed arm after self-admin0.20.30.7-0.5-0.6-0.5-0.6-0.3-0.50.5-0.40.4-0.6-0.5-0.6-0.4-0.1-0.40.6-0.60.6-0.0-0.9
Time in open arm before self-admin1.01.03.2-1.0-1.1-1.0-1.0-0.9-1.01.0-0.90.9-1.1-1.0-1.0-0.9-0.7-0.91.0-1.01.0-0.6-1.8
Time in open arm after self-admin0.20.30.60.50.50.50.50.30.5-0.50.5-0.50.40.60.50.60.80.5-0.50.5-0.50.40.5
Sum of active levers in priming session hrs 5-60.10.10.30.30.50.40.30.30.4-0.30.3-0.30.50.40.40.30.30.3-0.40.4-0.40.10.3
Time to tail flick, vehicle, before self-admin1.11.11.81.01.21.11.11.41.1-1.01.0-1.01.01.11.11.00.91.0-1.11.1-1.11.40.5
Time to tail flick, vehicle, after self-admin0.00.00.20.0-0.2-0.0-0.1-0.1-0.1-0.00.0-0.1-0.10.1-0.10.10.50.10.1-0.10.10.2-0.3
Time to tail flick, test, before self-admin0.80.81.60.90.90.80.70.60.8-0.91.0-1.00.80.90.81.01.30.9-0.80.8-0.80.91.3
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.4-0.3-0.4-0.5-0.30.3-0.20.2-0.4-0.3-0.3-0.10.2-0.30.3-0.30.40.1-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.4-0.6-0.5-0.4-0.7-0.50.4-0.40.4-0.4-0.4-0.5-0.4-0.3-0.40.5-0.50.5-0.6-0.5
Delta time to tail flick, test, before/after SA0.40.41.3-0.6-0.7-0.6-0.6-0.6-0.60.6-0.60.6-0.7-0.6-0.6-0.6-0.5-0.60.6-0.60.6-0.3-1.1
Ambulatory time before self-admin3.94.14.72.02.02.02.12.02.0-2.02.0-2.02.02.12.02.02.02.0-2.02.0-2.01.82.2
Ambulatory time after self-admin1.11.21.81.11.21.11.31.31.1-1.10.9-0.91.31.11.20.90.61.1-1.21.2-1.20.71.3
Total heroin consumption2.53.03.3-1.8-1.6-1.8-1.8-1.5-1.81.8-1.81.8-1.7-1.7-1.8-1.8-1.8-1.81.8-1.81.8-1.8-1.3
Area under the delay curve1.61.73.0-1.3-1.3-1.3-1.4-1.5-1.31.3-1.31.2-1.3-1.3-1.3-1.3-1.2-1.31.3-1.31.3-1.7-0.6
Delay disc. indifference point, 0s delay1.61.72.2-1.3-1.4-1.3-1.4-1.4-1.31.3-1.21.2-1.4-1.3-1.4-1.3-1.2-1.31.4-1.41.4-1.5-0.5
Delay disc. indifference point, 16s delay1.81.82.8-1.3-1.3-1.4-1.4-1.5-1.41.3-1.31.3-1.3-1.3-1.4-1.3-1.3-1.31.4-1.41.4-1.7-0.7
Delay disc. indifference point, 2s delay0.91.01.6-1.0-1.1-1.0-1.0-1.1-1.01.0-0.90.9-1.1-1.0-1.0-0.9-0.9-1.01.0-1.01.1-1.3-0.1
Delay disc. indifference point, 24s delay1.51.52.2-1.2-1.3-1.2-1.2-1.4-1.21.2-1.21.2-1.3-1.2-1.3-1.2-1.1-1.21.2-1.21.3-1.5-0.8
Delay disc. indifference point, 4s delay0.50.51.0-0.7-0.7-0.7-0.7-0.8-0.70.7-0.60.6-0.7-0.7-0.7-0.6-0.6-0.70.7-0.70.7-1.0-0.3
Delay disc. indifference point, 8s delay4.14.26.8-2.0-2.0-2.0-2.1-2.3-2.02.1-2.02.0-2.0-2.1-2.0-2.1-2.2-2.12.0-2.02.0-2.6-1.2
Delay discount exponential model param1.41.42.71.21.21.21.21.41.2-1.21.1-1.11.21.21.21.11.11.2-1.21.2-1.21.60.6
Delay discount hyperbolic model param1.21.32.51.11.21.11.21.31.1-1.11.1-1.11.21.21.11.11.01.1-1.21.2-1.21.60.5
Fecal boli incidents, locomotor time 10.50.60.80.70.90.80.80.60.8-0.80.7-0.70.90.70.90.60.50.7-0.90.9-0.90.70.3
Change in fecal boli incidents, locomotor task0.60.61.0-0.7-0.9-0.8-0.9-0.9-0.80.7-0.70.6-0.9-0.7-0.8-0.6-0.3-0.70.9-0.90.9-1.00.2
Time >=10cm from walls, locomotor time 10.80.81.5-0.8-0.8-0.8-0.7-1.1-0.80.9-0.90.9-0.8-0.9-0.8-0.9-1.2-0.90.8-0.80.8-0.9-1.1
Bouts of movement, locomotor time 10.30.43.4-0.5-0.5-0.5-0.6-0.1-0.50.5-0.50.5-0.5-0.5-0.4-0.5-0.3-0.50.5-0.50.50.2-1.8
Total resting periods, locomotor time 10.10.11.70.10.10.1-0.10.40.1-0.10.1-0.10.10.10.10.10.20.1-0.10.1-0.10.7-1.3
Rest time, locomotor task time 10.10.20.90.20.20.20.10.60.2-0.30.2-0.20.20.20.30.30.60.2-0.20.2-0.20.8-1.0
Distance moved, locomotor task time 10.10.11.10.30.40.30.4-0.00.4-0.30.3-0.30.40.30.30.2-0.20.3-0.30.3-0.4-0.21.0
Vertical activity count, locomotor time 11.21.31.9-1.1-1.1-1.1-1.1-1.0-1.11.1-1.11.1-1.1-1.1-1.1-1.2-1.4-1.11.1-1.11.1-1.2-1.1
Time >=10cm from walls, locomotor time 20.20.20.40.40.50.50.60.50.5-0.40.4-0.40.50.50.50.40.30.4-0.50.5-0.50.60.1
Bouts of movement, locomotor time 23.43.63.8-1.9-1.9-1.9-1.9-1.8-1.91.9-1.91.9-1.9-1.9-1.9-1.9-1.9-1.91.9-1.91.9-1.9-1.7
Total resting periods, locomotor time 23.53.84.0-1.9-2.0-2.0-2.0-1.9-2.02.0-1.91.9-2.0-1.9-2.0-1.9-1.9-1.92.0-2.02.0-2.0-1.6
Rest time, locomotor task time 20.20.20.6-0.4-0.5-0.4-0.6-0.5-0.40.4-0.40.3-0.5-0.4-0.4-0.3-0.1-0.40.4-0.40.5-0.1-0.8
Distance moved, locomotor task time 20.30.30.50.60.70.60.70.60.6-0.60.5-0.50.70.60.60.50.40.6-0.60.6-0.60.40.4
Vertical activity count, locomotor time 20.20.20.6-0.5-0.5-0.5-0.4-0.2-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.50.5-0.50.5-0.6-0.8
Weight adjusted by age2.32.63.6-1.6-1.8-1.7-1.7-1.9-1.71.6-1.51.5-1.8-1.6-1.7-1.5-1.3-1.61.7-1.71.7-1.4-1.2
Seeking ratio, delayed vs. immediate footshock0.30.30.5-0.5-0.6-0.5-0.7-0.7-0.50.5-0.50.5-0.6-0.6-0.5-0.5-0.5-0.50.5-0.50.5-0.60.1
Locomotion in novel chamber0.70.91.6-1.0-1.0-1.0-1.0-1.3-1.01.0-0.90.9-1.1-1.0-1.0-0.8-0.7-1.01.0-1.01.0-0.90.0
Locomotion in novel chamber post-restriction0.70.81.6-0.9-0.8-0.9-0.8-1.1-0.80.9-0.90.9-0.8-0.9-0.9-0.9-1.3-0.90.9-0.90.9-1.1-0.0
Progressive ratio0.10.11.9-0.1-0.1-0.1-0.1-0.4-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.1-0.71.4
Food seeking constrained by brief footshock0.00.10.5-0.2-0.0-0.1-0.1-0.3-0.10.2-0.30.3-0.0-0.2-0.1-0.3-0.7-0.20.1-0.10.1-0.1-0.1
Seeking ratio, punishment vs. effort0.10.11.4-0.1-0.0-0.1-0.00.1-0.10.1-0.10.20.0-0.1-0.1-0.2-0.3-0.10.1-0.00.00.4-1.2
Run reversals in cocaine runway, females0.40.40.90.60.50.60.60.80.6-0.60.6-0.60.40.70.60.71.00.6-0.60.6-0.50.60.3
Run reversals in cocaine runway, males1.31.32.81.01.31.01.01.51.0-1.11.1-1.11.01.01.01.11.31.0-1.01.0-1.01.71.0
Latency to leave start box in cocaine runway0.00.00.70.10.10.10.1-0.10.1-0.10.1-0.10.00.10.10.10.20.1-0.10.1-0.1-0.30.8
Latency to leave start box in cocaine runway, F1.92.13.11.41.51.41.41.41.4-1.41.4-1.41.41.41.41.51.61.4-1.41.4-1.41.31.8
Latency to leave start box in cocaine runway, M2.62.54.3-1.5-1.6-1.5-1.5-1.8-1.51.5-1.51.5-1.5-1.6-1.5-1.6-1.7-1.61.5-1.51.5-2.1-1.0
Cd content in liver0.30.30.60.60.60.60.50.60.6-0.60.6-0.70.50.50.50.60.60.6-0.50.5-0.50.50.8
Co content in liver0.20.20.30.50.40.50.60.50.5-0.50.5-0.50.50.60.50.40.50.5-0.50.5-0.50.50.2
Cu content in liver1.51.82.0-1.4-1.3-1.3-1.3-1.3-1.31.4-1.41.4-1.3-1.4-1.3-1.3-1.4-1.41.3-1.31.3-1.3-1.1
Fe content in liver0.10.10.30.30.30.40.40.50.4-0.30.3-0.30.40.40.40.30.30.4-0.40.4-0.40.5-0.2
K content in liver1.51.51.8-1.3-1.2-1.2-1.3-1.4-1.21.2-1.21.2-1.2-1.3-1.2-1.2-1.3-1.31.3-1.31.3-1.3-0.9
Mg content in liver0.00.00.1-0.2-0.2-0.2-0.2-0.3-0.10.1-0.10.1-0.1-0.2-0.2-0.1-0.1-0.20.2-0.20.2-0.30.1
Mn content in liver0.20.20.3-0.5-0.4-0.5-0.5-0.5-0.40.5-0.40.4-0.5-0.5-0.4-0.4-0.3-0.50.5-0.50.5-0.50.3
Na content in liver0.20.20.3-0.4-0.3-0.4-0.5-0.6-0.40.4-0.40.4-0.5-0.5-0.4-0.3-0.5-0.50.4-0.40.4-0.40.4
Rb content in liver0.00.00.10.10.00.10.10.00.1-0.10.2-0.20.10.10.10.20.30.1-0.10.1-0.1-0.00.4
Se content in liver0.30.40.50.60.60.60.50.50.6-0.60.7-0.70.60.60.60.70.60.6-0.60.6-0.60.50.7
Sr content in liver1.00.91.1-0.9-1.0-0.9-0.9-0.9-0.90.9-0.91.0-0.9-0.9-0.9-1.0-1.0-0.90.9-0.90.9-0.9-1.1
Zn content in liver0.40.40.80.60.60.60.60.70.6-0.60.6-0.60.60.60.60.70.70.6-0.60.6-0.60.60.9