Slc48a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000053196 0.26 0.12 0.0e+00 0.31 0.31 0.31 0.31 2.3e-35 5.2e-35 1.5e-34 6.6e-35
2 BLA gene expression ENSRNOG00000053196 0.25 0.14 2.5e-12 0.22 0.07 0.23 0.08 3.9e-12 1.8e-04 2.5e-12 4.7e-05
3 Brain gene expression ENSRNOG00000053196 0.46 0.14 0.0e+00 0.58 0.59 0.59 0.59 9.5e-66 4.1e-67 2.1e-67 1.6e-67
4 Brain intron excision ratio chr7:128915406:128921137 0.04 0.04 1.6e-03 0.03 0.03 0.02 0.02 1.2e-03 1.9e-03 3.2e-03 2.6e-03
5 IL gene expression ENSRNOG00000053196 0.33 0.16 1.2e-07 0.28 0.26 0.21 0.28 2.4e-07 5.9e-07 8.9e-06 1.6e-07
6 LHb gene expression ENSRNOG00000053196 0.57 0.19 2.1e-07 0.18 0.22 0.17 0.17 4.9e-05 6.1e-06 9.2e-05 7.4e-05
7 Liver alternative TSS ENSRNOT00000079388 0.02 0.02 2.8e-03 0.01 0.02 0.01 0.01 1.2e-02 6.1e-03 2.4e-02 2.7e-02
8 Liver alternative TSS ENSRNOT00000105518 0.03 0.03 4.6e-04 0.03 0.03 0.02 0.02 6.4e-04 6.6e-04 1.0e-03 1.1e-03
9 Liver gene expression ENSRNOG00000053196 0.02 0.02 5.5e-03 0.01 0 0 0 6.2e-02 9.2e-02 3.1e-01 1.7e-01
10 NAcc gene expression ENSRNOG00000053196 0.39 0.21 0.0e+00 0.24 0.26 0.25 0.26 4.7e-18 1.1e-19 1.2e-18 1.3e-19
11 OFC mRNA stability ENSRNOG00000053196 0.11 0.09 5.3e-03 0.13 0.09 0.09 0.11 6.7e-04 3.1e-03 3.7e-03 1.2e-03
12 PL gene expression ENSRNOG00000053196 0.29 0.13 0.0e+00 0.35 0.34 0.34 0.34 2.5e-27 2.6e-26 1.0e-26 8.1e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail4.815.417.34.14.03.9-3.43.93.7-4.03.64.24.0-4.04.1
BMI without tail0.10.20.50.40.70.3-0.40.40.2-0.40.20.60.3-0.40.5
Body weight7.431.135.05.75.85.7-5.15.65.4-5.65.15.75.6-5.75.9
Epididymis fat weight0.61.52.31.21.11.3-0.71.21.3-1.21.51.01.3-1.21.4
Glucose0.10.20.60.30.60.3-0.70.30.2-0.40.00.60.3-0.30.3
Heart weight0.00.00.10.0-0.20.10.30.10.1-0.1-0.20.00.10.00.1
Left kidney weight0.41.01.61.00.61.3-0.11.11.0-1.10.91.11.2-1.11.2
Right kidney weight2.98.310.02.92.93.1-2.73.02.8-2.92.12.92.9-3.03.2
Tail length0.00.10.3-0.30.0-0.20.1-0.2-0.30.3-0.5-0.3-0.40.3-0.2
Length with tail2.28.29.62.93.03.0-2.62.92.8-2.92.42.82.9-2.93.1
Length without tail7.917.219.34.33.94.3-3.44.24.2-4.24.04.14.3-4.34.4
Liver weight, left1.93.13.71.61.91.8-1.71.81.6-1.81.91.91.7-1.71.8
Liver weight, right1.93.23.91.82.01.8-1.81.81.7-1.81.41.91.7-1.81.9
Parametrial fat weight1.01.93.6-1.4-1.6-1.41.9-1.4-1.01.4-0.4-1.7-1.21.3-1.3
Retroperitoneal fat weight0.10.31.7-0.4-1.0-0.21.3-0.3-0.00.4-0.3-0.8-0.10.4-0.2
Intraocular pressure10.114.216.9-4.0-3.4-4.12.9-4.1-4.13.9-3.0-3.4-4.14.0-4.0
Extensor digitorum longus weight6.224.928.95.14.95.1-4.35.15.4-5.14.84.45.2-5.05.2
Soleus weight1.13.24.61.81.61.9-1.41.92.1-1.81.71.31.9-1.91.9
Tibialis anterior weight2.69.012.33.12.93.1-2.73.13.5-3.02.82.43.2-3.13.1
Tibia length6.217.423.54.04.94.1-4.44.03.7-4.24.14.63.9-4.14.0
Number of licking bursts0.20.20.6-0.5-0.2-0.5-0.3-0.5-0.50.5-0.8-0.3-0.60.5-0.5
Food consumed during 24 hour testing period1.11.41.71.21.21.3-0.61.21.1-1.21.31.21.3-1.21.2
Times rat made contact with spout0.10.10.20.3-0.10.30.40.30.5-0.30.5-0.10.4-0.30.3
Mean time between licks in bursts0.50.60.9-0.9-0.7-0.90.5-0.9-1.00.8-0.5-0.6-0.90.9-0.9
Mean num. licks in bursts0.10.21.00.2-0.30.21.00.20.2-0.20.6-0.20.4-0.20.2
Std. dev. time between licks in bursts1.01.21.5-1.2-0.9-1.20.7-1.2-1.11.1-0.9-1.0-1.21.2-1.2
Water consumed over 24 hours0.20.20.40.40.10.50.20.50.6-0.40.50.00.5-0.40.4
Indifference point 0 sec1.52.33.4-1.4-1.5-1.51.7-1.5-1.31.6-1.5-1.8-1.51.5-1.4
Indifference point AUC0.10.10.4-0.5-0.3-0.20.2-0.4-0.00.3-0.2-0.6-0.20.3-0.3
Indifference point function ln k3.44.85.72.42.22.2-2.12.22.1-2.22.02.32.2-2.32.3
Indifference point function log k3.44.85.72.42.22.2-2.12.22.1-2.22.02.32.2-2.32.3
Delay discounting total patch changes 0 sec1.42.23.3-1.4-1.4-1.51.5-1.5-1.31.5-1.4-1.8-1.51.5-1.5
Delay discounting total patch changes 12 sec1.21.62.7-1.4-1.2-1.21.2-1.3-1.01.3-1.1-1.6-1.21.4-1.3
Delay discounting total patch changes 18 sec3.03.95.3-2.2-1.7-1.91.7-2.1-1.82.0-2.0-2.3-2.02.1-2.0
Delay discounting total patch changes 24 sec1.01.22.1-1.2-0.9-1.10.7-1.2-0.91.2-1.2-1.4-1.21.1-1.1
Delay discounting total patch changes 6 sec2.33.54.2-2.1-1.8-1.81.8-1.9-1.81.9-2.0-2.0-1.81.9-1.8
Delay discounting time to switch 0 sec3.14.85.6-2.3-2.1-2.21.8-2.3-2.22.2-2.0-2.1-2.32.4-2.3
Delay discounting water rate 0 sec4.67.38.42.82.72.7-2.42.72.8-2.72.92.42.8-2.82.8
Delay discounting water rate 12 sec3.85.76.22.42.42.4-2.32.42.3-2.42.42.42.4-2.52.4
Delay discounting water rate 18 sec0.81.01.51.00.91.0-0.71.11.2-1.11.00.71.1-1.11.1
Delay discounting water rate 24 sec3.54.87.32.22.22.1-2.22.12.3-2.22.71.92.2-2.12.0
Delay discounting water rate 6 sec4.76.97.62.72.52.7-2.42.72.7-2.72.82.52.7-2.72.6
Locomotor activity0.81.31.7-1.1-1.1-1.20.9-1.2-1.21.2-1.3-1.1-1.21.2-1.2
Locomotor testing distance2.64.25.1-2.0-2.0-2.11.6-2.1-2.12.1-2.3-1.9-2.22.0-2.0
Locomotor testing rearing2.43.85.6-2.0-1.7-1.91.2-2.0-2.02.0-2.4-1.8-2.12.0-2.0
Light reinforcement 12.74.96.5-2.4-1.8-2.31.4-2.3-2.12.2-2.1-2.2-2.42.5-2.5
Light reinforcement 20.91.21.5-1.2-1.0-1.10.8-1.1-1.11.1-1.2-0.9-1.11.2-1.2
Reaction time number correct0.50.81.90.80.60.8-0.90.70.8-0.91.40.90.8-0.90.9
Reaction time mean minus median9.512.313.5-3.5-3.6-3.53.6-3.5-3.73.5-3.5-3.3-3.53.5-3.5
Reaction time mean minus median AUC7.09.09.9-3.0-3.1-2.93.0-3.1-3.13.0-2.9-2.7-3.03.1-3.0
Reaction time num false alarms1.92.63.3-1.5-1.8-1.71.8-1.5-1.41.6-1.6-1.8-1.51.6-1.6
Reaction time num false alarms AUC3.24.45.4-2.0-2.3-2.22.3-2.0-2.02.1-2.1-2.2-2.02.0-2.0
Reaction time trials correct on left0.50.81.90.80.60.8-0.90.70.8-0.91.40.90.8-0.90.9
Reaction time trials on left0.40.51.50.60.40.6-0.70.50.6-0.71.20.80.6-0.70.7
Reaction time mean0.81.11.7-1.1-1.0-0.90.9-1.1-1.31.0-1.0-0.6-1.11.2-1.1
Reaction time mean AUC0.50.71.1-0.9-0.8-0.70.8-0.8-1.10.8-0.7-0.4-0.81.0-0.9
Median of all reaction times0.00.00.2-0.10.20.2-0.2-0.1-0.30.00.00.4-0.10.3-0.0
Reaction time omissions10.113.615.1-3.8-3.9-3.63.6-3.7-3.63.7-3.7-3.6-3.63.8-3.7
Reaction time false alarm rate2.43.44.5-1.7-1.9-1.92.1-1.7-1.71.8-2.1-2.0-1.71.8-1.8
Reaction time premature initiation rate3.85.17.3-2.5-2.4-2.12.1-2.3-1.82.2-2.0-2.7-2.22.3-2.3
Reaction time premature initiations2.23.24.5-2.0-2.0-1.71.6-1.9-1.41.8-1.3-2.1-1.71.8-1.8
Std. dev. reaction times7.09.611.0-3.1-3.2-3.13.0-3.1-3.33.1-3.0-2.8-3.13.2-3.1
Reaction time trials completed0.40.51.50.60.40.6-0.70.50.6-0.71.20.80.6-0.70.7
Reaction time trials AUC0.81.12.41.00.81.0-1.10.91.0-1.01.51.11.0-1.11.1
Social response proportion0.70.71.8-0.9-0.6-0.80.7-0.9-1.10.8-1.3-0.5-0.90.7-0.6
Social responses8.611.114.1-3.4-3.3-3.43.0-3.4-3.23.4-3.8-3.4-3.43.1-3.1
Social time0.91.22.6-1.0-0.6-1.00.9-1.0-1.61.0-1.6-0.4-1.21.0-0.9
Conditioned locomotion0.00.10.5-0.20.2-0.2-0.7-0.2-0.10.1-0.00.1-0.20.1-0.1
Cocaine response after cond. corrected0.10.10.50.3-0.20.30.70.30.2-0.20.10.10.4-0.20.3
Cocaine response after cond. not corrected0.91.02.1-0.9-1.2-0.81.4-0.9-1.00.9-1.0-0.9-0.81.0-0.8
Cocaine response before conditioning6.37.79.1-3.0-2.5-2.91.9-2.9-3.02.9-2.6-2.5-3.02.9-3.0
Saline control response0.10.10.4-0.50.2-0.30.0-0.4-0.60.30.0-0.0-0.50.5-0.4
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.0-0.00.0-0.10.10.1-0.3-0.2-0.10.1-0.1
Condit. Reinf. active-inactive response ratio0.20.20.8-0.4-0.5-0.40.6-0.4-0.30.4-0.9-0.5-0.40.5-0.4
Condit. Reinf. active responses0.20.30.4-0.7-0.4-0.40.3-0.6-0.40.5-0.7-0.6-0.50.6-0.6
Condit. Reinf. inactive responses0.91.11.5-1.2-0.9-1.00.6-1.1-1.01.1-1.1-1.0-1.11.2-1.1
Condit. Reinf. lever presses0.00.00.1-0.30.0-0.00.2-0.2-0.10.1-0.0-0.2-0.10.2-0.2
Condit. Reinf. lever reinforcers received0.50.70.9-0.9-0.7-0.70.7-0.9-0.70.8-1.0-0.9-0.80.9-0.9
Pavlov. Cond. lever latency0.10.10.20.40.00.20.00.30.4-0.20.10.00.3-0.40.3
Pavlov. Cond. magazine entry latency0.30.30.80.50.90.5-0.80.50.2-0.50.10.90.4-0.50.5
Pavlov. Cond. change in total contacts0.71.02.10.81.41.0-1.20.90.6-1.00.81.40.9-0.80.9
Pavlov. Cond. index score0.10.20.60.20.80.4-0.70.30.1-0.40.20.70.3-0.20.3
Pavlov. Cond. latency score0.20.30.70.30.80.5-0.70.40.2-0.50.20.80.4-0.30.4
Pavlov. Cond. lever contacts0.30.40.6-0.7-0.3-0.60.4-0.7-0.80.6-0.5-0.3-0.70.8-0.7
Pavlov. Cond. magazine entry number1.21.52.7-1.1-1.6-1.21.7-1.1-0.91.2-0.7-1.6-1.01.1-1.1
Pavlov. Cond. intertrial magazine entries2.63.46.2-1.7-2.5-1.82.3-1.8-1.31.8-1.0-2.3-1.61.7-1.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.41.00.6-1.00.50.3-0.60.41.00.5-0.40.5
Pavlov. Cond. response bias0.20.20.4-0.6-0.1-0.40.1-0.5-0.60.4-0.5-0.1-0.50.6-0.5
Conditioned reinforcement - actives1.51.51.9-1.3-1.2-1.41.1-1.3-1.11.2-0.9-1.3-1.21.3-1.2
Conditioned reinforcement - inactives1.11.31.7-1.2-1.3-1.21.2-1.1-1.01.1-1.0-1.2-1.01.2-1.1
Conditioned locomotion0.20.30.5-0.6-0.4-0.60.3-0.6-0.40.5-0.2-0.6-0.60.7-0.7
Intermittent access intake day 1-15 change1.01.01.4-1.0-1.1-0.91.2-0.9-0.90.9-0.8-1.0-0.91.1-1.1
Intermittent access intake escalation0.60.61.1-0.8-0.9-0.71.0-0.7-0.70.7-0.6-0.8-0.70.9-0.9
Intermittent access intake escalation 21.01.01.5-1.1-1.1-0.81.2-0.9-0.90.9-0.8-1.0-0.81.1-1.1
Intermitt. access day 1 inactive lever presses3.13.44.3-1.9-1.7-2.11.3-1.9-1.61.9-1.8-2.0-1.91.9-1.9
Intermitt. access day 15 inactive lever presses0.91.01.9-1.0-0.9-1.00.7-1.1-0.91.0-1.4-1.0-1.01.0-1.0
Intermitt. access escalation Index0.30.30.4-0.6-0.4-0.60.2-0.6-0.60.6-0.4-0.4-0.60.5-0.6
Intermittent access day 1 total infusions1.51.71.8-1.2-1.3-1.41.2-1.3-1.41.3-1.3-1.2-1.31.3-1.3
Intermittent access day 15 total infusions2.42.73.1-1.7-1.7-1.61.5-1.6-1.61.6-1.7-1.5-1.61.8-1.7
Intermittent access terminal intake (last 3 days)2.52.83.2-1.7-1.7-1.71.6-1.6-1.71.6-1.7-1.6-1.61.8-1.7
Intermittent access total infusions2.42.73.1-1.7-1.6-1.61.5-1.6-1.71.6-1.5-1.5-1.61.8-1.7
Intermittent access day 1 locomotion1.01.01.5-1.0-0.8-1.20.4-1.0-1.01.0-1.0-0.9-1.11.1-1.1
Intermittent access day 15 total locomotion0.90.91.5-1.0-0.8-1.00.3-1.0-0.91.0-1.2-0.9-1.01.1-1.1
Intermittent access total locomotion2.22.53.4-1.7-1.4-1.70.9-1.6-1.41.6-1.4-1.7-1.71.8-1.8
Intermittent access standard deviation0.70.71.1-0.7-0.9-0.80.9-0.7-0.90.8-1.0-0.7-0.80.9-0.8
Cocaine induced anxiety1.21.32.31.01.21.0-1.21.01.3-1.21.51.01.2-1.11.1
Post-drug Anxiety4.44.86.82.12.32.1-2.22.12.2-2.22.62.12.2-2.12.1
Baseline Anxiety1.11.11.51.21.11.1-1.01.20.8-1.00.81.21.0-1.11.1
Lifetime Intake1.82.12.4-1.5-1.4-1.41.3-1.4-1.51.4-1.3-1.3-1.41.6-1.5
Incentive Sensitization - Responses0.10.10.10.30.30.2-0.30.20.2-0.2-0.20.20.2-0.30.3
Incentive Sensitization - Breakpoint0.00.00.20.10.20.0-0.20.00.0-0.0-0.40.10.0-0.10.2
Progressive ratio test 1 active lever presses3.33.44.1-2.0-1.7-2.01.5-1.9-1.81.9-1.7-1.8-1.92.0-2.0
Progressive ratio test 1 breakpoint3.13.23.8-1.9-1.6-2.01.4-1.8-1.81.8-1.7-1.7-1.81.9-1.9
Progressive ratio test 1 inactive lever presses2.32.53.1-1.6-1.6-1.81.3-1.7-1.41.6-1.7-1.6-1.51.6-1.5
Progressive ratio test 2 active lever presses1.61.72.1-1.4-1.1-1.30.9-1.3-1.21.3-1.4-1.3-1.41.4-1.3
Progressive ratio test 2 breakpoint2.12.42.9-1.7-1.4-1.61.1-1.6-1.51.6-1.6-1.5-1.61.7-1.6
Progressive ratio test 2 inactive lever presses2.73.13.9-1.8-1.7-2.01.4-1.8-1.71.8-1.9-1.8-1.81.8-1.7
Total sessions with >9 infusions0.40.40.6-0.6-0.5-0.80.4-0.6-0.80.6-0.8-0.4-0.70.7-0.7
Short access day 1 total inactive lever presses0.70.81.1-1.1-0.9-1.10.8-1.0-0.80.9-0.6-0.9-0.91.0-1.0
Short access day 10 total inactive lever presses0.30.30.7-0.7-0.5-0.50.3-0.6-0.30.5-0.4-0.8-0.50.7-0.6
Short access day 1 total infusions0.00.00.10.20.20.0-0.20.20.1-0.2-0.20.30.2-0.20.2
Short access day 10 total infusions0.60.60.8-0.8-0.9-0.80.9-0.7-0.80.8-0.7-0.8-0.80.9-0.9
Short access total infusions0.10.20.2-0.4-0.3-0.40.4-0.4-0.40.4-0.4-0.3-0.40.5-0.5
Short access day 1 locomotion0.10.10.50.20.2-0.2-0.40.1-0.0-0.1-0.70.3-0.0-0.10.2
Short access day 10 total locomotion0.10.10.2-0.30.0-0.3-0.4-0.2-0.20.3-0.2-0.4-0.40.4-0.4
Short access total locomotion0.10.10.2-0.3-0.1-0.5-0.1-0.3-0.30.3-0.3-0.3-0.40.5-0.5
Compulsive drug intake0.50.50.70.80.90.6-0.60.70.7-0.70.70.70.7-0.80.8
One hour access (0.3 mA shock)0.20.30.7-0.5-0.5-0.40.5-0.5-0.50.4-0.8-0.5-0.40.5-0.5
One hour access (shock baseline)0.00.00.3-0.1-0.1-0.00.1-0.1-0.10.1-0.5-0.0-0.10.1-0.1
Number of responses in last shaping day0.40.50.80.60.80.7-0.90.70.7-0.70.30.70.7-0.60.6
Context. condit. distance diff. score0.40.50.60.70.70.7-0.60.70.8-0.70.70.60.7-0.70.7
Locomotion velocity, session 10.60.61.2-0.7-1.0-0.70.7-0.7-0.40.7-1.0-1.1-0.70.7-0.7
Locomotion distance, session 13.03.85.2-1.9-2.2-1.82.3-1.8-1.91.9-2.0-2.0-1.81.9-1.9
Locomotion velocity, session 20.20.30.6-0.5-0.7-0.40.8-0.5-0.30.5-0.4-0.7-0.40.4-0.5
Locomotion distance, session 22.23.24.6-1.7-2.0-1.72.1-1.7-1.71.8-1.5-1.9-1.71.7-1.7
Locomotion velocity, session 33.23.74.8-1.8-2.1-1.92.2-1.9-1.71.9-2.0-2.1-1.81.8-1.8
Locomotion distance, session 35.15.65.8-2.4-2.4-2.42.4-2.4-2.42.4-2.2-2.3-2.32.4-2.4
Stereotopy head waving bouts, day 30.81.01.81.00.91.0-1.31.01.0-1.01.01.10.9-0.91.0
Stereotopy head waving duration, day 30.30.30.70.50.40.5-0.80.50.5-0.60.60.60.5-0.50.5
Locomotion velocity, session 70.00.00.1-0.1-0.1-0.30.1-0.2-0.10.1-0.1-0.2-0.10.1-0.1
Locomotion distance, session 71.11.41.9-1.2-0.9-1.30.9-1.2-1.21.2-1.4-1.1-1.31.2-1.2
Stereotopy head waving bouts, day 71.11.31.81.11.01.1-1.31.11.3-1.11.30.91.1-1.11.1
Stereotopy head waving duration, day 71.82.23.31.41.21.5-1.51.51.8-1.51.81.11.5-1.51.4
Locomotion velocity, session 80.20.20.50.50.10.5-0.10.50.7-0.50.70.10.6-0.40.5
Locomotion distance, session 80.91.42.7-1.1-1.4-1.11.6-1.1-1.01.1-0.8-1.4-1.01.1-1.1
Degree of sensitization distance0.80.81.11.01.00.9-1.00.90.9-0.90.70.90.9-0.91.0
Degree of sensitization stereotypy0.70.81.50.80.70.8-0.90.81.2-0.91.20.40.9-0.80.8
Condit. Reinf. active minus inactive responses0.10.10.4-0.3-0.6-0.30.6-0.3-0.40.3-0.2-0.2-0.30.4-0.3
Condit. Reinf. active-inactive response ratio0.10.10.10.30.10.40.10.40.2-0.30.30.40.4-0.30.3
Condit. Reinf. active responses0.60.81.3-0.8-1.2-0.81.0-0.8-0.90.9-0.9-0.8-0.80.9-0.8
Condit. Reinf. inactive responses2.83.44.4-1.8-1.9-1.81.5-1.8-1.81.9-2.1-1.8-1.91.8-1.8
Incentive salience index mean0.00.00.10.10.10.2-0.00.1-0.0-0.10.30.30.1-0.10.1
Condit. Reinf. lever presses0.20.30.60.40.50.5-0.60.50.2-0.50.60.80.4-0.40.4
Time in familiar zone, hab. session 10.30.30.9-0.4-0.7-0.40.9-0.4-0.30.4-0.7-0.6-0.30.4-0.4
Time in novel zone, hab. session 10.20.21.20.20.80.2-1.10.20.1-0.30.60.60.1-0.30.2
Total zone transitions, hab. session 10.20.30.4-0.6-0.5-0.60.5-0.6-0.50.6-0.4-0.6-0.60.6-0.6
Total locomotion distance, hab. session 10.00.10.1-0.3-0.2-0.20.2-0.2-0.20.20.3-0.1-0.20.3-0.3
Locomotion velocity, hab. session 10.00.00.1-0.2-0.1-0.10.1-0.1-0.10.10.3-0.0-0.10.2-0.2
Time in familiar zone, hab. session 20.00.00.20.10.30.2-0.00.1-0.1-0.2-0.00.40.1-0.10.1
Time in novel zone, hab. session 20.00.00.2-0.1-0.3-0.1-0.3-0.10.30.10.1-0.5-0.10.1-0.1
Total zone transitions, hab. session 20.10.10.6-0.2-0.5-0.30.8-0.2-0.20.3-0.1-0.4-0.20.2-0.2
Total locomotion distance, hab. session 20.20.20.5-0.4-0.6-0.50.7-0.4-0.50.4-0.3-0.4-0.40.4-0.4
Locomotion velocity, hab. session 20.00.10.3-0.2-0.4-0.20.5-0.2-0.20.2-0.1-0.2-0.10.2-0.2
Novel to familiar place preference ratio1.21.32.81.01.61.0-1.71.00.8-1.00.81.30.9-1.01.0
Novelty place preference0.80.82.20.71.40.7-1.50.70.5-0.80.61.10.6-0.70.7
Time in novel zone, NPP test0.60.62.10.61.40.6-1.50.60.4-0.60.51.00.4-0.60.6
Total zone transitions, NPP test1.01.42.3-1.2-1.4-1.11.5-1.1-1.21.2-1.0-1.1-1.11.2-1.2
Total locomotion distance, NPP test2.43.34.1-1.9-1.8-1.91.8-1.9-2.01.8-1.6-1.6-1.91.9-1.9
Locomotion velocity, NPP test1.31.92.4-1.4-1.4-1.41.4-1.4-1.61.4-1.1-1.1-1.41.4-1.4
Pavlov. Cond. lever latency0.00.10.20.2-0.10.2-0.00.20.5-0.2-0.1-0.20.3-0.20.2
Pavlov. Cond. magazine entry latency0.00.00.2-0.1-0.1-0.20.4-0.2-0.30.10.10.0-0.10.0-0.1
Pavlov. Cond. change in total contacts0.00.00.1-0.00.20.0-0.2-0.0-0.2-0.00.10.3-0.00.0-0.0
Pavlov. Cond. index score0.10.10.40.20.50.2-0.40.20.1-0.30.60.60.2-0.30.2
Pavlov. Cond. latency score0.10.10.30.10.40.1-0.30.1-0.1-0.20.50.50.1-0.20.1
Pavlov. Cond. lever contacts0.30.40.8-0.7-0.4-0.70.4-0.7-0.90.6-0.3-0.3-0.70.7-0.7
Pavlov. Cond. magazine entry number0.00.00.10.10.00.2-0.20.10.2-0.1-0.3-0.10.1-0.10.1
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.7-1.1-0.70.8-0.7-0.80.8-0.9-0.7-0.70.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.50.90.60.80.6-0.60.60.5-0.71.00.90.6-0.70.6
Pavlov. Cond. response bias0.10.10.2-0.3-0.2-0.40.4-0.4-0.50.30.1-0.1-0.30.3-0.3
Bone: apparent density7.512.516.73.54.13.5-3.13.52.9-3.63.34.13.4-3.53.6
Bone surface10.117.821.24.34.64.3-3.74.23.9-4.34.24.54.2-4.24.3
Bone volume6.711.314.93.43.93.4-3.13.42.8-3.43.13.83.3-3.33.4
Bone: connectivity density5.58.710.83.03.33.0-2.43.02.6-3.02.93.33.0-2.93.0
Bone: cortical apparent density0.50.60.8-0.9-0.7-0.80.4-0.9-0.80.8-0.6-0.7-0.90.8-0.9
Bone: cortical area9.915.017.53.94.23.9-3.63.93.6-3.93.74.03.8-3.93.9
Bone: cortical porosity2.12.32.9-1.6-1.3-1.70.9-1.6-1.71.6-1.6-1.3-1.71.5-1.5
Bone: cortical porosity2.52.73.4-1.7-1.5-1.81.1-1.8-1.81.7-1.5-1.5-1.81.7-1.7
Bone: cortical thickness4.06.77.92.62.82.6-2.32.62.3-2.62.52.82.5-2.72.6
Bone: cortical thickness0.20.30.40.60.60.5-0.30.50.3-0.50.00.60.5-0.60.6
Bone: cortical tissue density0.60.81.0-1.0-0.8-0.90.5-1.0-0.90.9-0.7-0.8-1.01.0-1.0
Bone: elastic displacement4.85.55.9-2.4-2.3-2.42.1-2.4-2.32.4-2.1-2.4-2.42.4-2.4
Bone: elastic work0.10.10.2-0.4-0.1-0.30.1-0.4-0.40.3-0.2-0.2-0.40.4-0.4
Bone: endosteal estimation7.616.317.34.14.14.1-3.84.14.2-4.14.03.84.1-4.04.1
Bone: endosteal perimeter7.014.416.33.94.03.8-3.63.83.7-3.83.63.83.8-3.83.9
Bone: final force9.715.817.14.14.14.1-3.44.13.8-4.03.84.14.0-4.04.1
Bone: final moment9.715.917.14.14.14.1-3.34.13.8-4.13.94.14.1-4.14.1
Bone: marrow area7.616.417.84.14.14.1-3.84.14.2-4.14.03.84.1-4.14.1
Bone: maximum diameter4.88.910.23.13.23.0-2.83.03.0-3.02.62.93.0-3.13.1
Bone: maximum force12.521.725.64.75.14.7-4.24.74.4-4.74.54.84.6-4.74.7
Bone: maximum moment12.421.625.34.75.04.7-4.24.74.4-4.74.44.84.6-4.74.7
Bone: minimum diameter8.014.817.93.94.23.9-4.03.83.6-3.83.64.13.7-3.83.8
Bone: periosteal estimation12.024.527.25.05.25.0-4.65.04.8-5.04.85.04.9-5.05.0
Bone: periosteal perimeter10.817.919.54.34.44.3-3.64.34.2-4.34.14.24.3-4.34.3
Bone: post-yield work8.611.713.23.53.53.5-3.23.53.6-3.43.43.13.4-3.53.5
Bone: stiffness15.424.327.55.05.24.9-4.55.04.7-5.04.75.14.9-5.15.1
Bone: tissue strength0.30.30.60.40.80.6-0.80.50.4-0.60.60.70.5-0.40.4
Bone: trabecular number3.96.08.42.52.72.5-1.82.52.0-2.52.32.92.5-2.42.5
Bone: trabecular spacing1.11.42.5-1.2-1.4-1.20.7-1.2-0.81.2-1.2-1.6-1.11.1-1.2
Bone: trabecular thickness0.40.51.1-0.6-0.2-0.60.7-0.6-1.00.7-0.9-0.3-0.70.7-0.7
Bone: trabecular tissue density0.10.10.2-0.5-0.1-0.4-0.1-0.4-0.40.4-0.2-0.3-0.40.5-0.5
Breakpoint value in progressive ratio session0.10.20.40.20.40.4-0.40.30.4-0.40.60.40.4-0.30.4
Distance traveled before self-admin1.01.01.3-1.0-0.9-1.10.6-1.1-1.01.1-1.0-1.1-1.11.1-1.1
Distance traveled after self-admin0.10.10.2-0.3-0.3-0.20.5-0.3-0.20.20.4-0.4-0.20.4-0.4
Delta time in closed arm before/after self-admin0.10.10.20.30.10.20.20.20.1-0.30.20.50.3-0.30.3
Delta time in open arm before/after self-admin3.73.54.5-2.0-1.9-1.71.7-1.8-1.81.9-2.0-2.1-1.92.0-1.9
Diff in mean of infusions in LGA sessions0.91.01.41.01.01.2-0.71.00.9-1.10.81.11.1-1.11.1
Extinction: sum of active levers before priming0.50.50.70.60.70.7-0.70.70.9-0.70.50.60.8-0.70.7
Active lever presses in extinction session 60.40.40.50.60.50.6-0.30.70.6-0.60.50.60.7-0.70.7
Delta distance traveled before/after self-admin0.20.20.70.40.20.40.20.40.4-0.40.80.30.5-0.30.3
Delta ambulatory time before/after self-admin0.10.10.80.20.20.30.10.30.3-0.30.90.20.4-0.20.2
Time in closed arm before self-admin1.01.21.91.11.30.9-1.41.11.1-1.10.91.01.0-1.01.0
Time in closed arm after self-admin0.30.30.50.60.70.4-0.70.40.4-0.50.30.70.5-0.60.6
Time in open arm before self-admin1.01.11.51.11.11.1-1.11.00.9-1.00.61.21.0-1.11.1
Time in open arm after self-admin0.30.31.1-0.5-0.5-0.30.2-0.4-0.60.5-1.1-0.5-0.60.4-0.5
Sum of active levers in priming session hrs 5-60.20.20.3-0.5-0.4-0.40.3-0.4-0.40.4-0.2-0.4-0.40.5-0.5
Time to tail flick, vehicle, before self-admin1.31.31.8-1.2-1.2-1.21.3-1.2-1.01.1-0.9-1.2-1.01.1-1.0
Time to tail flick, vehicle, after self-admin0.10.10.70.20.40.1-0.80.1-0.1-0.1-0.50.3-0.1-0.20.1
Time to tail flick, test, before self-admin0.80.71.8-0.8-0.8-0.70.6-0.8-1.00.8-1.3-0.6-0.90.8-0.9
Time to tail flick, test, after self-admin0.10.10.20.30.10.4-0.40.30.3-0.30.20.40.3-0.40.4
Delta time to tail flick, vehicle, before/after SA0.30.30.80.70.70.6-0.90.60.3-0.50.20.70.4-0.60.5
Delta time to tail flick, test, before/after SA0.50.40.70.70.50.6-0.50.60.7-0.60.80.50.6-0.60.7
Ambulatory time before self-admin3.63.74.2-2.0-1.8-1.91.5-2.0-1.92.0-1.9-2.1-2.02.0-2.0
Ambulatory time after self-admin1.21.31.8-1.3-1.0-1.21.0-1.2-1.01.2-0.6-1.3-1.21.3-1.4
Total heroin consumption2.73.24.61.62.01.7-2.11.71.9-1.82.01.61.7-1.71.7
Area under the delay curve1.61.72.21.31.21.5-0.91.41.2-1.31.21.31.4-1.31.4
Delay disc. indifference point, 0s delay1.71.92.11.41.41.4-1.41.41.4-1.41.21.41.3-1.41.4
Delay disc. indifference point, 16s delay1.81.92.21.31.51.5-1.21.41.4-1.41.31.41.4-1.31.4
Delay disc. indifference point, 2s delay1.01.11.31.11.11.1-1.11.11.0-1.01.01.11.0-1.11.1
Delay disc. indifference point, 24s delay1.61.62.01.31.41.4-1.21.31.2-1.21.01.31.2-1.31.3
Delay disc. indifference point, 4s delay0.40.40.70.70.40.8-0.10.80.6-0.70.50.70.8-0.70.7
Delay disc. indifference point, 8s delay3.94.14.92.01.92.2-1.52.22.0-2.02.22.02.1-2.02.1
Delay discount exponential model param1.31.41.9-1.2-1.1-1.40.8-1.3-1.11.2-1.0-1.2-1.21.2-1.3
Delay discount hyperbolic model param1.21.31.8-1.2-1.1-1.30.8-1.3-1.11.1-1.0-1.2-1.21.2-1.2
Fecal boli incidents, locomotor time 10.91.02.9-0.9-1.3-0.71.7-0.9-0.90.9-0.2-1.0-0.70.9-1.0
Change in fecal boli incidents, locomotor task0.80.81.10.91.01.0-1.00.90.8-0.80.10.90.8-1.01.1
Time >=10cm from walls, locomotor time 10.70.71.40.80.71.0-0.50.80.8-0.81.20.80.9-0.80.9
Bouts of movement, locomotor time 10.10.10.30.50.30.2-0.20.30.3-0.50.50.60.5-0.30.3
Total resting periods, locomotor time 10.00.10.1-0.1-0.2-0.30.3-0.3-0.20.1-0.0-0.0-0.10.3-0.3
Rest time, locomotor task time 10.10.10.4-0.2-0.4-0.50.4-0.4-0.40.3-0.6-0.2-0.20.2-0.3
Distance moved, locomotor task time 10.10.10.2-0.4-0.2-0.20.1-0.2-0.20.30.3-0.4-0.30.4-0.3
Vertical activity count, locomotor time 11.11.22.01.11.01.0-0.71.11.0-1.11.41.01.1-1.11.2
Time >=10cm from walls, locomotor time 20.20.20.3-0.5-0.5-0.50.6-0.5-0.50.5-0.3-0.5-0.50.4-0.4
Bouts of movement, locomotor time 23.43.64.21.92.01.9-2.01.82.0-1.91.91.81.9-1.82.0
Total resting periods, locomotor time 23.63.84.32.02.02.0-2.01.92.1-2.01.81.82.0-1.82.0
Rest time, locomotor task time 20.10.20.30.50.30.5-0.40.40.3-0.40.00.50.4-0.40.5
Distance moved, locomotor task time 20.30.30.5-0.7-0.6-0.60.5-0.6-0.60.6-0.4-0.6-0.60.6-0.6
Vertical activity count, locomotor time 20.20.20.30.50.50.3-0.40.50.6-0.50.50.30.5-0.50.5
Weight adjusted by age2.73.04.31.71.91.9-2.11.71.6-1.71.21.81.6-1.81.8
Seeking ratio, delayed vs. immediate footshock0.20.30.40.60.30.60.00.60.3-0.50.40.70.6-0.60.6
Locomotion in novel chamber0.81.01.41.00.81.2-1.11.11.1-1.00.60.91.0-1.11.2
Locomotion in novel chamber post-restriction0.70.81.40.90.80.9-0.71.01.1-0.91.20.70.9-0.80.9
Progressive ratio0.00.00.1-0.1-0.10.30.30.10.2-0.0-0.1-0.10.1-0.10.0
Food seeking constrained by brief footshock0.00.10.5-0.0-0.10.20.20.00.3-0.10.7-0.20.2-0.0-0.0
Seeking ratio, punishment vs. effort0.00.00.30.10.1-0.1-0.3-0.00.1-0.10.50.10.00.00.0
Run reversals in cocaine runway, females0.30.30.9-0.5-0.3-0.60.1-0.5-0.70.6-1.0-0.3-0.70.4-0.5
Run reversals in cocaine runway, males1.31.21.6-1.2-1.1-1.21.1-1.2-0.91.1-1.1-1.2-1.01.0-1.0
Latency to leave start box in cocaine runway0.00.00.0-0.1-0.10.0-0.1-0.0-0.00.1-0.1-0.0-0.10.0-0.1
Latency to leave start box in cocaine runway, F1.81.92.2-1.5-1.3-1.41.0-1.5-1.31.4-1.5-1.3-1.41.4-1.5
Latency to leave start box in cocaine runway, M2.42.33.01.71.31.7-1.11.71.6-1.51.71.41.6-1.51.5
Cd content in liver0.30.30.3-0.5-0.5-0.50.6-0.5-0.50.5-0.6-0.6-0.50.4-0.5
Co content in liver0.20.20.5-0.5-0.2-0.50.1-0.5-0.70.5-0.4-0.1-0.60.3-0.6
Cu content in liver1.41.71.91.31.11.3-1.01.31.4-1.31.31.21.4-1.41.3
Fe content in liver0.10.10.2-0.4-0.3-0.40.3-0.4-0.40.4-0.4-0.3-0.40.2-0.4
K content in liver1.41.42.01.20.91.3-0.61.31.4-1.21.00.91.4-1.41.3
Mg content in liver0.00.00.10.20.00.2-0.00.20.1-0.2-0.10.20.2-0.30.2
Mn content in liver0.20.20.50.50.20.5-0.30.50.7-0.40.10.10.5-0.60.5
Na content in liver0.20.20.60.50.10.5-0.10.50.8-0.40.2-0.00.5-0.50.5
Rb content in liver0.00.00.1-0.1-0.1-0.1-0.0-0.1-0.10.1-0.3-0.1-0.10.1-0.1
Se content in liver0.30.40.7-0.6-0.7-0.50.8-0.5-0.60.6-0.8-0.6-0.50.6-0.5
Sr content in liver1.00.91.10.91.10.9-1.00.90.9-0.91.01.00.9-0.90.9
Zn content in liver0.40.40.8-0.6-0.8-0.60.6-0.6-0.40.6-0.7-0.9-0.60.6-0.6