Shisal1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000052725 0.41 0.18 1.1e-08 0.07 0.15 0.16 0.16 1.9e-04 1.6e-08 5.5e-09 1.2e-08
2 BLA mRNA stability ENSRNOG00000052725 0.18 0.1 1.4e-07 0.06 0.11 0.1 0.1 2.3e-04 2.8e-06 4.8e-06 5.8e-06
3 Brain gene expression ENSRNOG00000052725 0.24 0.12 1.8e-13 0.14 0.15 0.16 0.17 3.8e-13 5.3e-14 1.2e-14 3.5e-15
4 Brain mRNA stability ENSRNOG00000052725 0.27 0.1 9.4e-16 0.16 0.16 0.16 0.16 1.6e-14 5.6e-15 3.3e-14 1.4e-14
5 LHb gene expression ENSRNOG00000052725 0.19 0.1 3.6e-04 0.11 0.14 0.05 0.05 1.3e-03 4.1e-04 2.6e-02 2.1e-02
6 Liver gene expression ENSRNOG00000052725 0.2 0.09 0.0e+00 0.14 0.11 0.15 0.15 2.7e-15 2.3e-12 5.5e-16 4.8e-16
7 NAcc mRNA stability ENSRNOG00000052725 0.16 0.09 1.0e-05 0.06 0.05 0.06 0.06 3.9e-05 2.3e-04 5.3e-05 2.7e-05
8 PL gene expression ENSRNOG00000052725 0.12 0.07 2.3e-06 0.09 0.07 0.07 0.07 5.1e-07 5.2e-06 4.6e-06 3.0e-06
9 PL mRNA stability ENSRNOG00000052725 0.19 0.09 1.3e-08 0.1 0.1 0.1 0.11 7.7e-08 7.4e-08 4.0e-08 6.6e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.92.98.00.72.0-2.20.82.82.11.3-1.01.0
BMI without tail1.94.06.5-1.62.4-2.12.11.2-0.52.2-2.52.4
Body weight0.62.74.7-0.22.2-2.01.72.10.91.7-1.51.5
Epididymis fat weight0.20.50.9-0.11.0-0.80.61.00.60.7-0.60.6
Glucose1.52.33.80.8-1.91.9-1.6-1.4-0.3-1.71.7-1.7
Heart weight0.10.20.40.70.1-0.1-0.10.60.60.00.4-0.4
Left kidney weight7.621.944.10.35.9-6.43.36.64.24.6-3.73.7
Right kidney weight7.621.848.60.95.8-6.43.07.04.84.3-3.33.3
Tail length0.20.51.4-0.90.20.00.7-0.7-1.20.3-0.80.7
Length with tail0.00.10.4-0.20.4-0.30.60.1-0.20.4-0.40.4
Length without tail0.51.23.41.7-0.3-0.2-0.91.11.8-0.61.1-1.0
Liver weight, left0.20.41.00.80.0-0.5-0.70.81.0-0.30.2-0.2
Liver weight, right0.10.20.3-0.50.4-0.40.50.1-0.20.4-0.60.5
Parametrial fat weight0.00.10.50.3-0.2-0.0-0.7-0.20.4-0.20.1-0.1
Retroperitoneal fat weight0.51.83.70.01.7-1.90.81.81.11.3-1.11.1
Intraocular pressure0.10.10.4-0.40.3-0.10.70.1-0.40.4-0.20.2
Extensor digitorum longus weight0.41.52.3-1.21.4-1.31.30.5-0.41.4-1.51.5
Soleus weight0.30.92.11.4-0.2-0.1-0.91.11.4-0.60.9-0.8
Tibialis anterior weight0.00.00.1-0.1-0.1-0.1-0.3-0.2-0.0-0.1-0.20.1
Tibia length0.10.31.00.40.6-0.60.41.00.70.5-0.10.1
Number of licking bursts0.40.51.5-0.8-0.40.80.4-1.2-1.2-0.1-0.00.0
Food consumed during 24 hour testing period1.21.55.01.50.8-1.2-0.12.02.20.30.3-0.3
Times rat made contact with spout0.60.72.61.00.3-0.7-0.41.31.6-0.00.2-0.3
Mean time between licks in bursts1.01.53.7-0.5-1.31.7-0.3-1.9-1.6-0.90.7-0.7
Mean num. licks in bursts1.61.96.41.60.8-1.4-0.62.32.50.10.2-0.2
Std. dev. time between licks in bursts0.30.40.70.2-0.90.8-0.7-0.5-0.1-0.80.6-0.6
Water consumed over 24 hours1.31.54.00.91.3-1.50.72.01.80.9-0.40.4
Indifference point 0 sec0.00.10.20.1-0.40.4-0.2-0.40.0-0.30.1-0.1
Indifference point AUC0.60.71.10.9-0.80.7-1.1-0.00.6-1.01.1-1.0
Indifference point function ln k1.92.63.9-1.31.9-1.61.90.8-0.32.0-1.91.9
Indifference point function log k1.92.63.9-1.31.9-1.61.90.8-0.32.0-1.91.9
Delay discounting total patch changes 0 sec0.10.10.4-0.1-0.40.5-0.1-0.6-0.3-0.30.1-0.1
Delay discounting total patch changes 12 sec0.60.81.61.3-0.60.5-0.90.51.1-0.91.0-1.0
Delay discounting total patch changes 18 sec0.60.81.20.7-1.11.0-1.0-0.80.3-0.91.0-1.0
Delay discounting total patch changes 24 sec0.30.40.7-0.80.5-0.40.7-0.3-0.40.6-0.90.8
Delay discounting total patch changes 6 sec0.71.11.61.2-1.11.0-1.0-0.20.9-1.31.2-1.2
Delay discounting time to switch 0 sec0.20.40.7-0.80.4-0.40.4-0.2-0.50.6-0.80.8
Delay discounting water rate 0 sec0.10.20.50.10.5-0.40.60.70.40.4-0.20.2
Delay discounting water rate 12 sec2.23.35.5-2.01.9-1.62.30.1-1.12.1-2.02.1
Delay discounting water rate 18 sec0.00.00.00.0-0.0-0.10.1-0.1-0.10.00.0-0.0
Delay discounting water rate 24 sec1.21.73.1-0.61.6-1.81.21.10.51.5-1.41.4
Delay discounting water rate 6 sec0.10.20.6-0.6-0.10.10.3-0.6-0.80.2-0.20.2
Locomotor activity1.01.63.2-0.31.6-1.81.31.30.61.5-1.11.1
Locomotor testing distance0.00.00.1-0.20.0-0.10.2-0.2-0.30.20.00.0
Locomotor testing rearing0.30.50.8-0.70.8-0.80.90.3-0.20.9-0.70.7
Light reinforcement 12.13.86.0-1.72.1-2.12.10.5-0.32.5-2.32.4
Light reinforcement 22.93.96.0-1.92.2-2.02.20.7-0.62.3-2.52.4
Reaction time number correct0.40.61.6-0.5-0.80.9-0.1-1.2-1.3-0.40.3-0.3
Reaction time mean minus median0.10.10.20.3-0.20.40.00.10.3-0.20.5-0.4
Reaction time mean minus median AUC0.10.20.60.10.5-0.30.60.80.30.4-0.10.1
Reaction time num false alarms0.20.31.0-0.4-0.30.70.5-1.0-0.90.00.1-0.1
Reaction time num false alarms AUC0.10.10.5-0.1-0.30.50.3-0.7-0.6-0.00.2-0.2
Reaction time trials correct on left0.40.61.6-0.5-0.80.9-0.1-1.2-1.3-0.40.3-0.3
Reaction time trials on left0.40.61.6-0.5-0.81.0-0.1-1.2-1.3-0.50.4-0.4
Reaction time mean0.60.81.40.6-1.11.2-0.9-0.50.1-0.91.1-1.1
Reaction time mean AUC0.60.81.40.6-1.11.2-0.9-0.50.2-1.01.2-1.1
Median of all reaction times1.01.42.10.9-1.41.4-1.3-0.60.2-1.31.4-1.4
Reaction time omissions1.01.32.10.7-1.41.4-1.0-0.7-0.4-1.31.4-1.4
Reaction time false alarm rate0.00.00.10.00.10.00.3-0.2-0.00.2-0.00.0
Reaction time premature initiation rate1.11.53.51.7-0.3-0.2-1.31.41.9-0.71.1-1.1
Reaction time premature initiations0.71.01.81.4-0.70.3-1.20.81.2-0.91.2-1.1
Std. dev. reaction times0.10.10.30.3-0.40.5-0.20.00.3-0.20.6-0.5
Reaction time trials completed0.40.61.6-0.5-0.81.0-0.1-1.2-1.3-0.50.4-0.4
Reaction time trials AUC0.30.41.4-0.6-0.60.70.0-1.0-1.2-0.30.2-0.2
Social response proportion0.20.20.50.10.6-0.70.20.50.30.3-0.70.6
Social responses0.10.10.3-0.20.3-0.50.20.2-0.10.3-0.60.5
Social time2.73.55.71.2-2.42.0-2.3-1.6-0.3-2.31.8-1.9
Conditioned locomotion0.30.31.0-0.3-0.50.80.1-0.7-1.0-0.30.3-0.3
Cocaine response after cond. corrected0.50.61.1-1.00.5-0.10.9-0.5-1.00.7-0.80.8
Cocaine response after cond. not corrected1.21.32.4-1.50.7-0.21.5-0.7-1.51.1-1.11.1
Cocaine response before conditioning0.10.10.3-0.1-0.30.40.0-0.5-0.4-0.20.2-0.2
Saline control response0.50.71.1-1.00.5-0.31.0-0.6-0.90.8-0.90.9
Condit. Reinf. active minus inactive responses0.60.81.21.1-0.70.4-0.90.41.0-0.91.0-1.0
Condit. Reinf. active-inactive response ratio0.30.30.60.6-0.40.2-0.50.20.6-0.50.7-0.7
Condit. Reinf. active responses0.50.82.51.20.1-0.5-0.51.41.6-0.30.5-0.5
Condit. Reinf. inactive responses0.60.82.51.10.5-0.9-0.21.61.60.0-0.0-0.0
Condit. Reinf. lever presses0.10.10.50.30.2-0.4-0.20.70.5-0.1-0.20.1
Condit. Reinf. lever reinforcers received0.50.71.81.1-0.3-0.1-0.81.01.4-0.70.7-0.7
Pavlov. Cond. lever latency0.10.10.3-0.3-0.10.40.3-0.4-0.50.10.1-0.1
Pavlov. Cond. magazine entry latency0.91.12.60.8-1.30.9-1.6-0.60.3-1.40.9-0.9
Pavlov. Cond. change in total contacts0.71.02.41.5-0.5-0.2-1.30.81.5-0.80.7-0.7
Pavlov. Cond. index score0.40.51.40.7-0.80.3-1.2-0.10.5-0.90.5-0.5
Pavlov. Cond. latency score0.40.51.40.7-0.80.3-1.2-0.10.5-0.90.5-0.5
Pavlov. Cond. lever contacts0.20.20.70.6-0.0-0.4-0.60.50.8-0.30.1-0.1
Pavlov. Cond. magazine entry number0.40.51.6-0.80.8-0.31.30.2-0.61.0-0.50.6
Pavlov. Cond. intertrial magazine entries0.40.51.60.80.3-0.3-0.11.31.20.00.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.5-0.60.2-1.0-0.20.3-0.70.3-0.3
Pavlov. Cond. response bias0.40.61.31.0-0.60.1-1.10.30.9-0.80.6-0.6
Conditioned reinforcement - actives0.80.81.20.8-1.11.0-0.9-0.60.2-1.11.1-1.1
Conditioned reinforcement - inactives0.10.10.30.4-0.3-0.1-0.40.20.5-0.50.3-0.4
Conditioned locomotion1.61.93.2-0.71.6-1.81.40.80.41.6-1.61.6
Intermittent access intake day 1-15 change0.20.20.7-0.2-0.50.5-0.2-0.8-0.8-0.30.2-0.2
Intermittent access intake escalation0.30.31.1-0.6-0.20.40.2-0.8-1.10.1-0.20.2
Intermittent access intake escalation 20.30.30.50.1-0.70.7-0.4-0.6-0.3-0.40.6-0.6
Intermitt. access day 1 inactive lever presses0.80.92.40.70.9-1.40.11.51.50.3-0.50.3
Intermitt. access day 15 inactive lever presses1.71.95.82.10.0-0.6-1.11.82.4-0.70.9-0.9
Intermitt. access escalation Index0.10.00.1-0.40.2-0.00.1-0.1-0.00.3-0.30.3
Intermittent access day 1 total infusions0.20.31.00.60.4-0.40.30.81.00.1-0.00.0
Intermittent access day 15 total infusions0.10.10.4-0.10.4-0.30.60.20.10.4-0.40.4
Intermittent access terminal intake (last 3 days)0.10.10.20.20.3-0.50.30.40.50.2-0.20.2
Intermittent access total infusions0.20.20.5-0.10.6-0.40.70.50.40.5-0.50.5
Intermittent access day 1 locomotion0.20.20.5-0.40.5-0.30.7-0.1-0.20.6-0.60.6
Intermittent access day 15 total locomotion1.71.92.9-1.21.4-1.31.70.2-0.51.6-1.71.7
Intermittent access total locomotion1.21.42.1-0.71.4-1.41.30.70.01.4-1.41.4
Intermittent access standard deviation0.30.30.80.20.6-0.80.10.90.80.5-0.20.2
Cocaine induced anxiety2.02.35.50.51.8-2.00.82.31.71.3-1.11.1
Post-drug Anxiety1.01.13.20.61.1-1.50.21.81.30.5-0.50.4
Baseline Anxiety2.02.13.8-0.2-1.81.8-1.2-1.9-1.4-1.41.3-1.2
Lifetime Intake0.40.40.7-0.10.8-0.70.90.70.60.7-0.60.6
Incentive Sensitization - Responses1.51.54.91.50.5-1.0-0.72.02.20.10.5-0.4
Incentive Sensitization - Breakpoint1.71.75.61.60.6-1.1-0.62.22.40.10.4-0.3
Progressive ratio test 1 active lever presses0.10.10.20.1-0.50.4-0.3-0.20.0-0.40.5-0.4
Progressive ratio test 1 breakpoint0.30.30.60.2-0.70.6-0.5-0.4-0.1-0.70.7-0.6
Progressive ratio test 1 inactive lever presses0.10.10.20.30.0-0.2-0.30.40.5-0.20.2-0.2
Progressive ratio test 2 active lever presses0.80.82.51.3-0.2-0.2-0.81.11.6-0.40.8-0.7
Progressive ratio test 2 breakpoint0.91.02.81.5-0.2-0.1-0.81.21.7-0.61.0-0.9
Progressive ratio test 2 inactive lever presses0.81.02.61.4-0.3-0.1-0.81.11.6-0.80.9-0.9
Total sessions with >9 infusions0.60.61.5-0.90.7-0.51.2-0.1-0.60.8-0.90.9
Short access day 1 total inactive lever presses1.41.53.50.61.3-1.70.71.71.90.8-0.70.7
Short access day 10 total inactive lever presses2.12.34.5-0.11.9-2.11.01.91.71.4-1.21.2
Short access day 1 total infusions0.40.51.10.30.8-1.10.60.80.80.5-0.50.4
Short access day 10 total infusions0.10.10.2-0.3-0.30.50.3-0.4-0.4-0.20.0-0.1
Short access total infusions0.30.40.6-0.20.7-0.70.80.70.50.6-0.50.5
Short access day 1 locomotion0.10.10.3-0.30.3-0.50.4-0.20.00.4-0.50.5
Short access day 10 total locomotion0.30.31.2-0.5-0.50.5-0.0-1.1-1.1-0.2-0.00.0
Short access total locomotion0.20.20.3-0.50.2-0.20.5-0.4-0.40.3-0.50.5
Compulsive drug intake1.01.01.71.2-0.70.4-1.00.51.3-1.11.1-1.1
One hour access (0.3 mA shock)0.10.10.3-0.30.2-0.00.60.00.00.4-0.30.3
One hour access (shock baseline)1.11.32.4-1.50.7-0.21.4-0.7-1.31.2-1.21.3
Number of responses in last shaping day1.11.11.70.9-1.31.0-1.3-0.80.2-1.31.2-1.2
Context. condit. distance diff. score1.92.35.00.02.0-2.01.42.21.31.5-1.11.1
Locomotion velocity, session 11.01.12.60.31.2-1.60.51.51.20.9-0.70.7
Locomotion distance, session 10.10.20.30.5-0.40.2-0.5-0.10.3-0.50.5-0.5
Locomotion velocity, session 23.94.67.2-1.42.6-2.72.11.60.12.5-2.42.4
Locomotion distance, session 20.40.51.30.8-0.70.3-1.10.00.6-0.80.8-0.8
Locomotion velocity, session 32.42.84.2-1.22.1-2.01.91.1-0.02.0-1.91.9
Locomotion distance, session 31.01.12.2-1.50.5-0.21.1-0.8-1.50.8-1.01.0
Stereotopy head waving bouts, day 31.31.53.60.31.4-1.90.41.71.41.1-0.90.9
Stereotopy head waving duration, day 32.83.47.0-0.02.3-2.71.42.41.51.9-1.61.6
Locomotion velocity, session 70.60.71.1-0.80.9-0.71.00.5-0.40.9-0.90.9
Locomotion distance, session 70.10.10.1-0.1-0.30.3-0.3-0.3-0.3-0.30.1-0.1
Stereotopy head waving bouts, day 74.85.48.8-1.13.0-2.92.62.10.62.7-2.42.4
Stereotopy head waving duration, day 73.03.65.6-1.32.4-2.12.31.3-0.02.3-2.12.1
Locomotion velocity, session 84.95.911.90.23.0-3.41.83.42.32.3-1.81.8
Locomotion distance, session 81.11.73.2-0.31.7-1.81.11.70.91.4-1.11.1
Degree of sensitization distance1.31.33.81.7-0.1-0.3-1.21.41.9-0.70.9-0.9
Degree of sensitization stereotypy3.03.35.3-1.22.3-2.02.31.3-0.02.2-1.91.9
Condit. Reinf. active minus inactive responses1.61.73.10.6-1.71.7-1.3-1.2-0.5-1.51.4-1.4
Condit. Reinf. active-inactive response ratio1.01.01.90.6-1.21.4-0.9-0.7-0.3-1.11.2-1.2
Condit. Reinf. active responses1.41.73.1-0.1-1.61.8-1.1-1.7-1.2-1.31.0-1.0
Condit. Reinf. inactive responses0.30.41.3-0.4-0.70.7-0.5-1.1-0.8-0.50.1-0.1
Incentive salience index mean1.51.93.30.4-1.81.8-1.3-1.4-0.8-1.61.3-1.3
Condit. Reinf. lever presses0.50.71.3-0.1-1.01.0-0.7-1.1-0.8-0.90.6-0.6
Time in familiar zone, hab. session 10.60.51.0-0.20.9-1.00.60.80.40.8-0.70.7
Time in novel zone, hab. session 10.10.10.2-0.2-0.10.40.3-0.4-0.50.10.1-0.1
Total zone transitions, hab. session 11.01.52.50.3-1.61.5-1.2-1.4-0.6-1.41.1-1.1
Total locomotion distance, hab. session 10.40.61.0-1.00.6-0.60.7-0.3-0.60.8-1.01.0
Locomotion velocity, hab. session 10.40.61.0-0.90.7-0.80.6-0.2-0.50.7-1.01.0
Time in familiar zone, hab. session 20.30.30.6-0.80.4-0.40.5-0.3-0.70.6-0.70.7
Time in novel zone, hab. session 20.20.20.40.7-0.30.3-0.20.20.6-0.40.6-0.6
Total zone transitions, hab. session 20.40.51.70.90.1-0.6-0.60.91.3-0.30.3-0.3
Total locomotion distance, hab. session 20.20.30.7-0.30.6-0.80.30.40.30.5-0.60.6
Locomotion velocity, hab. session 20.10.10.4-0.10.4-0.60.10.30.40.3-0.40.4
Novel to familiar place preference ratio0.30.30.7-0.10.8-0.60.80.70.20.7-0.50.5
Novelty place preference0.70.71.3-0.31.1-0.91.10.90.21.0-0.70.7
Time in novel zone, NPP test0.80.91.7-0.31.2-1.01.31.00.21.2-0.80.8
Total zone transitions, NPP test0.30.40.60.7-0.60.4-0.8-0.10.4-0.70.7-0.7
Total locomotion distance, NPP test0.50.71.2-0.80.9-1.00.80.2-0.10.9-1.11.1
Locomotion velocity, NPP test0.30.40.8-0.90.5-0.60.5-0.2-0.50.6-0.90.9
Pavlov. Cond. lever latency0.91.12.50.11.4-1.30.81.60.91.1-0.70.7
Pavlov. Cond. magazine entry latency3.14.06.51.1-2.52.5-2.1-1.8-0.4-2.32.1-2.1
Pavlov. Cond. change in total contacts2.93.05.20.8-2.32.1-1.8-1.7-0.5-2.01.8-1.8
Pavlov. Cond. index score2.12.74.50.8-2.12.0-1.7-1.5-0.4-1.91.7-1.7
Pavlov. Cond. latency score1.31.62.80.5-1.71.6-1.2-1.4-0.4-1.51.3-1.3
Pavlov. Cond. lever contacts1.11.33.2-0.2-1.51.5-0.8-1.8-1.0-1.10.8-0.8
Pavlov. Cond. magazine entry number3.24.06.5-1.02.6-2.52.01.80.62.3-2.12.1
Pavlov. Cond. intertrial magazine entries0.00.10.20.1-0.30.2-0.3-0.4-0.1-0.20.1-0.1
Pavlov. Cond. lever-magazine prob. diff.2.43.05.00.7-2.22.2-1.7-1.8-0.7-2.01.8-1.8
Pavlov. Cond. response bias3.03.76.40.5-2.52.5-1.8-2.2-1.0-2.21.9-1.9
Bone: apparent density0.20.30.80.1-0.70.6-0.5-0.9-0.3-0.50.4-0.4
Bone surface0.00.10.10.3-0.40.2-0.3-0.30.1-0.20.3-0.3
Bone volume0.00.00.20.1-0.30.1-0.2-0.5-0.0-0.10.1-0.1
Bone: connectivity density0.10.10.5-0.1-0.40.4-0.2-0.7-0.3-0.20.2-0.1
Bone: cortical apparent density1.62.03.51.1-1.71.4-1.9-0.70.5-1.71.6-1.6
Bone: cortical area0.30.40.7-0.10.8-0.70.90.70.20.8-0.60.6
Bone: cortical porosity0.10.10.2-0.20.4-0.40.40.3-0.10.4-0.50.4
Bone: cortical porosity0.40.50.7-0.40.8-0.80.80.5-0.00.8-0.80.7
Bone: cortical thickness0.81.42.01.4-1.21.0-1.4-0.10.7-1.31.4-1.4
Bone: cortical thickness0.50.61.21.1-0.50.3-0.90.50.9-0.71.0-0.9
Bone: cortical tissue density1.41.83.31.1-1.61.3-1.8-0.60.6-1.61.5-1.5
Bone: elastic displacement1.61.82.7-0.91.7-1.51.60.90.21.6-1.51.5
Bone: elastic work3.95.18.6-0.82.9-2.92.32.31.02.6-2.32.3
Bone: endosteal estimation3.57.511.8-1.73.4-3.23.12.20.23.3-3.03.0
Bone: endosteal perimeter4.18.513.9-2.63.4-2.83.71.3-1.13.5-3.33.3
Bone: final force0.61.03.01.50.1-0.5-0.81.51.7-0.30.7-0.7
Bone: final moment0.81.44.11.70.3-0.7-0.71.92.0-0.20.6-0.6
Bone: marrow area3.57.511.9-1.63.4-3.33.12.20.33.3-2.92.9
Bone: maximum diameter3.56.410.5-1.03.2-3.12.92.50.73.0-2.52.5
Bone: maximum force0.81.34.41.20.9-1.20.02.11.90.40.0-0.0
Bone: maximum moment1.01.86.01.41.1-1.40.12.42.10.5-0.0-0.0
Bone: minimum diameter2.24.06.7-2.02.1-1.72.60.3-1.12.4-2.32.3
Bone: periosteal estimation2.34.87.6-1.22.8-2.62.51.90.32.6-2.32.3
Bone: periosteal perimeter3.35.410.0-2.02.7-2.23.21.1-0.82.8-2.62.6
Bone: post-yield work1.72.34.62.2-1.00.8-1.60.81.6-1.41.8-1.8
Bone: stiffness0.71.12.41.5-0.80.7-1.00.61.1-1.01.3-1.3
Bone: tissue strength0.20.20.60.80.1-0.2-0.30.70.7-0.20.3-0.4
Bone: trabecular number0.30.51.7-0.7-0.40.70.3-1.3-1.10.0-0.00.1
Bone: trabecular spacing0.81.03.10.41.1-1.40.41.81.10.7-0.60.6
Bone: trabecular thickness0.10.10.5-0.2-0.20.1-0.2-0.7-0.3-0.1-0.10.1
Bone: trabecular tissue density0.60.91.70.9-1.00.7-1.3-0.30.6-1.11.0-1.0
Breakpoint value in progressive ratio session0.20.30.5-0.40.6-0.60.30.30.10.6-0.70.7
Distance traveled before self-admin0.40.40.70.8-0.60.4-0.70.10.6-0.70.7-0.7
Distance traveled after self-admin0.30.40.90.20.6-0.90.30.71.00.3-0.50.4
Delta time in closed arm before/after self-admin1.21.22.11.2-0.80.4-1.50.41.3-1.11.1-1.2
Delta time in open arm before/after self-admin3.73.65.4-1.92.0-1.72.30.2-1.02.3-2.22.3
Diff in mean of infusions in LGA sessions4.75.38.22.3-2.41.9-2.8-0.21.3-2.72.9-2.8
Extinction: sum of active levers before priming0.30.30.50.7-0.40.3-0.70.40.4-0.60.5-0.5
Active lever presses in extinction session 60.30.31.00.70.1-0.3-0.41.00.8-0.20.4-0.5
Delta distance traveled before/after self-admin2.12.24.0-0.91.8-2.01.51.00.51.7-1.71.6
Delta ambulatory time before/after self-admin1.31.52.5-0.81.5-1.61.31.00.51.4-1.21.2
Time in closed arm before self-admin0.80.92.3-0.3-1.11.2-0.5-1.5-1.3-0.90.4-0.4
Time in closed arm after self-admin0.20.20.5-0.1-0.50.5-0.4-0.7-0.4-0.30.3-0.3
Time in open arm before self-admin0.10.10.1-0.3-0.20.40.0-0.2-0.2-0.30.2-0.2
Time in open arm after self-admin2.42.63.9-1.71.8-1.51.90.7-0.72.0-1.81.9
Sum of active levers in priming session hrs 5-60.20.20.4-0.00.5-0.60.20.60.30.4-0.50.4
Time to tail flick, vehicle, before self-admin0.10.10.40.60.1-0.4-0.20.50.30.0-0.00.0
Time to tail flick, vehicle, after self-admin0.30.30.9-0.70.2-0.00.5-0.4-1.00.4-0.50.5
Time to tail flick, test, before self-admin0.10.10.2-0.40.3-0.40.4-0.0-0.30.5-0.40.4
Time to tail flick, test, after self-admin0.80.91.8-0.1-1.21.1-0.9-1.3-0.8-0.90.8-0.8
Delta time to tail flick, vehicle, before/after SA0.20.20.50.40.0-0.1-0.30.60.7-0.00.4-0.3
Delta time to tail flick, test, before/after SA0.80.71.20.2-1.11.0-0.9-1.0-0.3-1.00.7-0.8
Ambulatory time before self-admin0.50.61.31.1-0.50.3-0.70.41.0-0.80.7-0.8
Ambulatory time after self-admin0.10.10.70.20.2-0.50.10.40.8-0.0-0.20.1
Total heroin consumption0.30.41.30.80.2-0.3-0.31.20.9-0.00.6-0.5
Area under the delay curve2.02.23.70.3-1.91.7-1.8-1.2-0.3-1.91.5-1.6
Delay disc. indifference point, 0s delay0.30.30.4-0.60.7-0.60.50.3-0.20.6-0.60.6
Delay disc. indifference point, 16s delay1.91.93.20.0-1.81.7-1.6-1.5-0.8-1.81.1-1.2
Delay disc. indifference point, 2s delay0.70.81.40.3-1.10.9-1.2-0.60.0-0.91.2-1.1
Delay disc. indifference point, 24s delay0.90.82.00.4-1.11.0-1.0-0.30.1-1.40.9-1.0
Delay disc. indifference point, 4s delay1.11.22.60.8-1.00.7-1.60.00.9-1.21.3-1.3
Delay disc. indifference point, 8s delay2.12.23.70.1-1.91.9-1.5-1.5-0.9-1.91.3-1.4
Delay discount exponential model param2.22.33.9-0.41.9-1.61.91.10.22.0-1.61.7
Delay discount hyperbolic model param1.61.73.0-0.31.7-1.41.70.90.11.7-1.41.5
Fecal boli incidents, locomotor time 10.00.00.1-0.10.1-0.3-0.10.30.4-0.10.00.0
Change in fecal boli incidents, locomotor task0.60.51.2-0.80.6-0.31.1-0.2-0.90.7-0.80.8
Time >=10cm from walls, locomotor time 10.20.20.6-0.30.6-0.50.30.50.40.8-0.40.5
Bouts of movement, locomotor time 10.30.30.60.6-0.50.3-0.80.00.4-0.80.4-0.6
Total resting periods, locomotor time 10.50.61.40.7-0.80.6-1.2-0.10.4-1.00.8-0.9
Rest time, locomotor task time 10.10.10.3-0.00.3-0.50.00.60.30.1-0.20.2
Distance moved, locomotor task time 10.00.00.1-0.00.1-0.10.00.00.30.30.10.0
Vertical activity count, locomotor time 10.10.10.20.1-0.40.3-0.4-0.20.3-0.10.4-0.4
Time >=10cm from walls, locomotor time 20.30.30.9-1.00.20.00.5-0.5-0.70.4-0.50.5
Bouts of movement, locomotor time 21.11.21.91.2-1.21.2-1.3-0.30.2-1.41.1-1.2
Total resting periods, locomotor time 21.61.72.71.5-1.31.4-1.5-0.20.4-1.71.4-1.5
Rest time, locomotor task time 20.10.20.30.1-0.50.5-0.5-0.4-0.2-0.50.3-0.3
Distance moved, locomotor task time 21.11.31.9-0.81.4-1.21.40.80.11.4-1.21.2
Vertical activity count, locomotor time 21.41.62.6-0.91.5-1.51.40.90.21.6-1.31.4
Weight adjusted by age1.01.11.8-0.91.1-1.31.00.7-0.21.1-1.31.2
Seeking ratio, delayed vs. immediate footshock0.91.03.0-0.5-0.91.4-0.0-1.7-1.6-0.7-0.0-0.2
Locomotion in novel chamber3.03.77.7-2.81.1-0.52.1-1.5-2.21.8-2.22.1
Locomotion in novel chamber post-restriction0.30.41.5-0.8-0.40.50.2-1.0-1.2-0.2-0.10.1
Progressive ratio1.11.32.10.8-1.31.2-1.2-0.30.4-1.41.4-1.4
Food seeking constrained by brief footshock0.30.40.90.30.7-0.90.30.70.60.7-0.50.5
Seeking ratio, punishment vs. effort0.60.81.5-0.01.1-1.20.70.70.31.1-0.91.0
Run reversals in cocaine runway, females1.71.75.1-1.8-0.20.50.6-2.1-2.20.6-0.90.9
Run reversals in cocaine runway, males0.60.51.3-0.30.9-0.61.10.4-0.11.0-0.70.8
Latency to leave start box in cocaine runway1.01.12.0-0.21.3-1.40.81.10.81.0-1.11.0
Latency to leave start box in cocaine runway, F0.20.20.50.50.4-0.70.00.60.70.2-0.40.3
Latency to leave start box in cocaine runway, M1.01.01.8-0.31.3-1.30.81.30.90.9-0.80.8
Cd content in liver0.30.30.80.3-0.50.8-0.20.10.2-0.40.9-0.9
Co content in liver0.81.02.0-0.11.2-1.40.90.70.41.2-1.21.1
Cu content in liver2.53.09.1-1.7-1.62.1-0.3-3.0-2.6-0.90.5-0.4
Fe content in liver0.20.20.4-0.40.5-0.60.50.10.20.5-0.70.6
K content in liver0.30.31.20.7-0.1-0.3-0.80.61.1-0.40.3-0.3
Mg content in liver0.30.30.90.5-0.50.1-1.00.10.7-0.70.6-0.6
Mn content in liver0.60.71.4-0.31.0-1.20.60.60.30.8-1.01.0
Na content in liver2.93.16.00.7-2.22.4-1.4-1.6-0.7-2.02.0-1.9
Rb content in liver0.30.40.70.3-0.80.7-0.7-0.40.1-0.70.8-0.8
Se content in liver0.10.10.4-0.5-0.10.0-0.1-0.6-0.30.1-0.00.1
Sr content in liver0.30.20.6-0.2-0.50.7-0.2-0.8-0.7-0.30.2-0.2
Zn content in liver0.40.51.5-0.6-0.60.8-0.1-1.2-1.1-0.40.2-0.2