Hub : Genes

Cacna1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000102295 0.04 0.03 3.8e-03 0 0 0 0 3.6e-01 2.7e-01 1.8e-01 1.7e-01
2 Adipose gene expression ENSRNOG00000052707 0.07 0.04 3.4e-06 0.05 0.05 0.04 0.05 1.9e-06 2.2e-06 1.9e-05 1.6e-06
3 Adipose mRNA stability ENSRNOG00000052707 0.04 0.03 6.2e-03 0.02 0.01 0.01 0.01 3.9e-03 3.4e-02 4.6e-02 2.7e-02
4 BLA gene expression ENSRNOG00000052707 0.1 0.06 1.1e-03 0.03 0.06 0.04 0.04 6.0e-03 6.4e-04 4.7e-03 2.5e-03
5 Brain gene expression ENSRNOG00000052707 0.04 0.02 3.4e-03 0.01 0.02 0.01 0.01 4.2e-02 1.2e-02 2.5e-02 1.7e-02
6 Brain intron excision ratio chr19:23624808:23626608 0.04 0.03 2.6e-03 0.03 0.02 0.03 0.02 5.7e-04 1.2e-02 1.9e-03 5.0e-03
7 Brain intron excision ratio chr19:23624814:23626608 0.05 0.03 1.1e-03 0.04 0.02 0.03 0.03 2.1e-04 3.3e-03 1.2e-03 1.5e-03
8 Brain mRNA stability ENSRNOG00000052707 0.19 0.07 0.0e+00 0.18 0.2 0.2 0.2 1.2e-16 7.0e-18 4.7e-18 2.6e-18
9 IL mRNA stability ENSRNOG00000052707 0.24 0.1 1.3e-04 0.13 0.12 0.15 0.12 6.3e-04 9.7e-04 2.1e-04 7.7e-04
10 NAcc intron excision ratio chr19:23624808:23626608 0.12 0.08 1.7e-04 0.04 0.05 0.06 0.03 3.2e-04 2.3e-04 5.2e-05 3.4e-03
11 NAcc intron excision ratio chr19:23624810:23626607 0.08 0.05 1.9e-04 0.05 0.05 0.04 0.04 1.1e-04 2.3e-04 3.1e-04 7.3e-04
12 PL gene expression ENSRNOG00000052707 0.07 0.04 7.4e-05 0.05 0.07 0.07 0.05 1.2e-04 9.7e-06 1.0e-05 7.0e-05
13 PL mRNA stability ENSRNOG00000052707 0.11 0.07 4.4e-03 0.01 0.03 0.03 0.03 5.3e-02 3.1e-03 2.2e-03 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.03.36.4-0.02.2-0.61.71.5-2.32.3-0.3-2.5-1.02.52.2-1.8
BMI without tail0.10.10.8-0.10.90.20.1-0.0-0.30.30.4-0.40.20.50.2-0.2
Body weight0.41.54.62.10.3-1.7-0.51.2-1.21.2-1.0-0.8-0.91.21.70.5
Epididymis fat weight0.61.43.51.9-0.7-1.8-0.41.3-0.90.9-1.6-0.4-0.90.91.60.4
Glucose0.50.74.32.10.10.0-0.1-0.80.0-0.0-0.50.00.6-0.00.41.9
Heart weight1.42.110.1-3.21.71.30.80.1-0.20.21.7-0.5-0.30.3-1.0-2.6
Left kidney weight0.30.82.80.6-1.2-1.7-1.51.3-0.10.1-0.60.5-0.7-0.10.5-0.1
Right kidney weight0.51.34.10.8-0.7-2.0-1.31.9-0.80.8-0.8-0.1-1.50.71.1-0.5
Tail length1.33.97.81.0-2.2-0.1-2.7-1.22.3-2.30.42.81.3-2.5-1.82.5
Length with tail0.62.15.82.4-1.9-1.2-2.1-0.30.9-0.9-0.81.6-0.2-1.2-0.42.3
Length without tail0.92.04.42.1-0.2-1.60.41.2-1.61.6-1.8-1.2-1.71.31.80.2
Liver weight, left0.71.13.60.6-1.9-1.7-0.51.6-0.20.2-1.70.4-0.10.21.1-0.3
Liver weight, right0.71.23.71.5-1.5-1.9-1.01.5-0.30.3-1.40.3-0.30.31.30.5
Parametrial fat weight0.20.41.81.3-0.8-0.8-0.60.20.1-0.1-0.90.40.3-0.00.51.0
Retroperitoneal fat weight1.44.812.63.6-0.3-3.1-0.72.4-2.02.0-2.4-1.3-1.92.13.10.6
Intraocular pressure1.11.66.0-1.02.51.11.4-0.6-1.21.21.0-1.5-1.11.1-0.1-1.2
Extensor digitorum longus weight0.41.83.71.90.1-1.50.31.1-1.51.5-1.4-1.2-1.61.61.70.1
Soleus weight0.20.51.0-0.2-0.2-0.90.31.0-0.70.7-0.7-0.6-0.90.90.7-1.0
Tibialis anterior weight0.10.31.30.31.10.1-0.2-0.4-0.30.30.9-0.3-0.80.3-0.40.2
Tibia length0.41.03.51.2-0.20.8-0.2-1.60.9-0.90.10.71.2-0.9-0.61.9
Number of licking bursts0.40.51.9-0.7-0.7-1.0-0.81.4-0.20.2-0.10.3-0.3-0.10.3-1.1
Food consumed during 24 hour testing period2.42.913.20.6-3.6-2.3-1.92.11.0-1.0-2.01.70.6-0.80.90.1
Times rat made contact with spout0.20.21.4-1.2-0.20.10.20.30.2-0.20.20.10.1-0.2-0.3-0.9
Mean time between licks in bursts0.20.31.2-1.10.5-0.1-0.60.50.0-0.01.00.1-0.2-0.2-0.3-1.0
Mean num. licks in bursts0.60.72.2-0.60.71.50.9-1.40.6-0.60.7-0.00.8-0.4-0.80.3
Std. dev. time between licks in bursts0.50.62.2-0.4-1.1-0.8-1.50.80.7-0.70.21.10.1-0.8-0.4-0.3
Water consumed over 24 hours0.50.62.8-0.7-1.7-0.9-0.41.10.4-0.4-0.90.70.6-0.40.3-0.7
Indifference point 0 sec0.40.62.01.40.60.2-1.2-0.60.5-0.50.90.60.2-0.2-0.51.4
Indifference point AUC0.60.73.60.3-1.9-0.9-0.60.60.4-0.4-1.30.90.8-0.50.40.5
Indifference point function ln k0.91.35.9-0.72.41.60.4-1.30.0-0.02.1-0.60.00.1-1.0-0.2
Indifference point function log k0.91.35.9-0.72.41.60.4-1.30.0-0.02.1-0.60.00.1-1.0-0.2
Delay discounting total patch changes 0 sec0.30.52.31.50.90.1-0.8-0.50.1-0.10.70.1-0.10.2-0.11.2
Delay discounting total patch changes 12 sec0.70.94.41.0-1.2-1.4-2.11.00.4-0.4-0.31.10.0-0.40.20.6
Delay discounting total patch changes 18 sec1.31.75.31.0-2.3-1.6-2.10.90.9-0.9-0.81.71.2-1.00.10.9
Delay discounting total patch changes 24 sec0.81.13.51.0-1.2-0.6-1.9-0.01.0-1.00.11.50.7-0.9-0.51.3
Delay discounting total patch changes 6 sec0.20.31.00.5-1.0-0.7-0.80.60.2-0.2-0.60.60.4-0.10.20.3
Delay discounting time to switch 0 sec0.10.20.70.1-0.5-0.7-0.40.8-0.20.2-0.40.0-0.50.10.3-0.5
Delay discounting water rate 0 sec0.20.31.21.10.1-0.40.2-0.1-0.20.2-0.6-0.30.10.50.60.9
Delay discounting water rate 12 sec0.91.33.9-2.01.11.60.7-1.20.7-0.71.60.11.0-0.7-1.4-0.8
Delay discounting water rate 18 sec2.73.56.5-1.40.72.4-0.5-2.32.1-2.12.51.32.2-2.1-2.50.7
Delay discounting water rate 24 sec1.01.44.3-1.21.31.6-0.2-1.41.1-1.12.10.40.7-0.9-1.60.1
Delay discounting water rate 6 sec1.21.85.30.1-2.3-1.0-1.50.41.5-1.5-0.51.71.8-1.5-0.30.9
Locomotor activity1.42.35.00.5-0.7-1.60.92.1-1.81.8-1.9-1.3-0.61.62.2-1.2
Locomotor testing distance1.32.24.50.2-1.0-1.31.12.1-1.61.6-1.9-1.2-0.51.52.1-1.4
Locomotor testing rearing1.11.76.0-0.4-2.2-2.0-0.82.5-0.40.4-1.50.3-0.30.31.2-1.4
Light reinforcement 14.58.227.22.3-5.2-3.6-4.32.12.2-2.2-2.03.51.4-2.00.52.3
Light reinforcement 24.45.820.02.8-4.5-2.9-3.11.31.7-1.7-2.22.61.1-1.60.72.6
Reaction time number correct0.60.93.3-1.01.81.40.6-1.20.1-0.11.5-0.40.20.0-1.0-0.2
Reaction time mean minus median0.40.51.21.01.10.30.7-0.6-0.80.8-0.2-0.9-1.00.50.20.4
Reaction time mean minus median AUC0.71.02.51.11.60.41.0-0.7-1.11.10.0-1.4-1.30.90.40.5
Reaction time num false alarms1.41.95.5-0.01.7-0.60.41.1-1.71.70.2-1.7-2.31.70.9-1.5
Reaction time num false alarms AUC0.81.23.0-0.71.70.10.50.6-1.11.10.7-1.3-1.61.20.2-1.6
Reaction time trials correct on left0.60.93.3-1.01.81.40.6-1.20.1-0.11.5-0.40.20.0-1.0-0.2
Reaction time trials on left0.60.83.5-0.91.91.30.6-1.10.0-0.01.4-0.50.10.2-0.9-0.3
Reaction time mean1.82.55.40.52.30.41.9-0.1-2.02.0-0.2-2.3-2.31.71.0-0.7
Reaction time mean AUC1.72.35.20.42.20.41.9-0.2-1.91.9-0.1-2.3-2.11.71.0-0.7
Median of all reaction times1.92.65.80.22.30.42.00.1-2.12.1-0.1-2.4-2.21.91.1-1.0
Reaction time omissions1.92.68.71.31.2-0.81.10.7-2.12.1-0.9-2.0-3.02.01.3-0.7
Reaction time false alarm rate0.30.51.4-0.00.6-0.40.10.8-0.80.80.1-0.8-1.20.80.5-1.0
Reaction time premature initiation rate3.04.19.30.5-2.8-0.9-3.0-0.12.3-2.30.13.01.9-2.5-1.31.6
Reaction time premature initiations1.82.65.9-0.0-1.7-0.3-2.3-0.52.0-2.00.72.41.7-2.1-1.51.2
Std. dev. reaction times0.70.92.80.71.20.21.1-0.3-1.21.2-0.4-1.3-1.70.80.4-0.1
Reaction time trials completed0.60.83.5-0.91.91.30.6-1.10.0-0.01.4-0.50.10.2-0.9-0.3
Reaction time trials AUC0.50.83.5-0.91.91.10.7-1.0-0.20.21.3-0.7-0.00.3-0.8-0.4
Social response proportion1.31.43.50.70.4-1.20.51.3-1.41.4-0.9-1.1-1.91.71.4-0.8
Social responses1.01.34.8-1.2-0.3-1.3-0.22.0-0.80.8-0.4-0.5-1.00.90.9-2.2
Social time0.70.91.7-1.3-0.30.7-0.7-0.51.0-1.01.11.01.1-1.3-1.3-0.3
Conditioned locomotion0.10.10.60.8-0.4-0.3-0.40.20.0-0.0-0.30.1-0.00.10.30.6
Cocaine response after cond. corrected1.51.73.41.40.2-1.30.51.3-1.51.5-1.3-1.3-1.51.61.8-0.3
Cocaine response after cond. not corrected2.02.24.51.2-0.1-1.60.61.7-1.71.7-1.7-1.4-1.61.72.1-0.6
Cocaine response before conditioning0.20.30.5-0.7-0.6-0.1-0.50.10.6-0.60.20.60.5-0.6-0.5-0.3
Saline control response1.92.68.91.3-2.3-3.0-1.42.5-0.50.5-2.10.4-0.80.51.7-0.3
Condit. Reinf. active minus inactive responses0.40.51.70.90.00.1-0.9-0.70.6-0.60.50.71.1-0.7-0.41.3
Condit. Reinf. active-inactive response ratio0.20.21.01.00.30.20.2-0.4-0.30.3-0.2-0.20.00.10.20.8
Condit. Reinf. active responses0.20.20.80.9-0.3-0.6-0.60.10.1-0.1-0.20.30.9-0.20.30.7
Condit. Reinf. inactive responses0.40.51.20.5-0.3-1.10.30.9-0.70.7-1.0-0.60.10.81.1-0.3
Condit. Reinf. lever presses0.00.10.3-0.10.10.10.50.0-0.30.3-0.2-0.30.20.30.3-0.2
Condit. Reinf. lever reinforcers received0.10.20.80.6-0.2-0.3-0.3-0.10.1-0.1-0.20.20.9-0.20.20.6
Pavlov. Cond. lever latency0.20.31.10.90.4-0.6-0.00.2-0.50.5-0.3-0.4-1.10.40.50.3
Pavlov. Cond. magazine entry latency0.00.00.20.1-0.1-0.2-0.40.1-0.00.00.10.1-0.50.2-0.1-0.0
Pavlov. Cond. change in total contacts0.50.71.6-0.90.11.1-0.1-0.90.8-0.81.00.61.2-0.7-1.00.1
Pavlov. Cond. index score0.20.30.7-0.7-0.20.7-0.1-0.50.6-0.60.60.50.8-0.5-0.70.0
Pavlov. Cond. latency score0.30.30.7-0.6-0.20.8-0.1-0.60.7-0.70.60.50.8-0.5-0.70.1
Pavlov. Cond. lever contacts0.10.10.5-0.7-0.60.1-0.00.20.3-0.3-0.00.30.5-0.2-0.2-0.4
Pavlov. Cond. magazine entry number0.10.10.2-0.1-0.1-0.40.20.5-0.30.3-0.4-0.2-0.20.10.4-0.4
Pavlov. Cond. intertrial magazine entries0.70.92.50.4-1.5-1.3-1.60.80.8-0.8-0.41.30.9-0.90.00.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.6-0.00.7-0.0-0.50.5-0.50.60.30.7-0.3-0.6-0.1
Pavlov. Cond. response bias0.00.00.1-0.2-0.30.20.1-0.10.1-0.1-0.00.10.40.0-0.1-0.1
Conditioned reinforcement - actives0.10.10.30.50.1-0.10.2-0.2-0.30.3-0.3-0.3-0.20.10.20.4
Conditioned reinforcement - inactives0.10.10.60.30.30.30.1-0.8-0.10.10.2-0.10.1-0.4-0.40.6
Conditioned locomotion0.10.10.5-0.20.30.40.2-0.30.1-0.10.4-0.10.7-0.3-0.1-0.0
Intermittent access intake day 1-15 change1.01.02.60.1-1.6-0.6-1.60.11.0-1.0-0.01.50.9-1.4-0.60.6
Intermittent access intake escalation1.21.23.50.4-1.9-0.7-1.60.21.1-1.1-0.21.50.8-1.4-0.40.9
Intermittent access intake escalation 21.51.52.9-0.1-1.6-0.0-1.7-0.31.5-1.50.41.71.3-1.7-0.90.9
Intermitt. access day 1 inactive lever presses1.51.63.5-0.30.51.6-0.4-1.71.2-1.21.41.01.9-1.2-1.31.4
Intermitt. access day 15 inactive lever presses0.30.30.70.90.2-0.10.6-0.0-0.70.7-0.5-0.7-0.20.60.80.3
Intermitt. access escalation Index0.10.10.3-0.0-0.5-0.4-0.40.50.2-0.2-0.20.30.5-0.10.3-0.1
Intermittent access day 1 total infusions0.50.61.60.31.30.31.2-0.3-0.90.9-0.2-1.2-0.31.00.6-0.1
Intermittent access day 15 total infusions0.10.10.40.5-0.10.0-0.1-0.50.1-0.1-0.00.10.1-0.3-0.20.7
Intermittent access terminal intake (last 3 days)0.10.20.70.50.20.30.1-0.80.0-0.00.1-0.00.3-0.3-0.20.8
Intermittent access total infusions0.10.10.30.60.40.10.4-0.5-0.30.3-0.1-0.30.10.10.10.5
Intermittent access day 1 locomotion0.40.41.3-0.11.20.70.9-0.5-0.30.30.4-0.61.00.30.30.0
Intermittent access day 15 total locomotion1.01.12.31.20.3-0.81.00.6-1.31.3-1.2-1.3-0.61.21.5-0.1
Intermittent access total locomotion1.11.22.31.00.8-0.51.30.4-1.41.4-1.0-1.5-0.31.31.5-0.1
Intermittent access standard deviation1.51.63.0-0.90.11.5-0.7-1.51.2-1.21.61.01.2-1.7-1.70.6
Cocaine induced anxiety0.10.10.60.20.40.40.0-0.80.2-0.20.30.1-0.0-0.3-0.50.6
Post-drug Anxiety0.40.40.8-0.40.90.40.8-0.2-0.80.80.1-0.9-0.80.40.1-0.7
Baseline Anxiety1.31.42.20.6-0.3-1.30.61.4-1.31.3-1.4-1.0-1.41.31.5-0.9
Lifetime Intake0.10.20.60.70.40.00.3-0.6-0.30.3-0.1-0.30.10.00.00.8
Incentive Sensitization - Responses0.20.20.6-0.50.00.5-0.2-0.50.3-0.30.50.3-0.2-0.5-0.8-0.1
Incentive Sensitization - Breakpoint0.20.20.6-0.5-0.00.5-0.3-0.50.4-0.40.50.4-0.2-0.6-0.8-0.1
Progressive ratio test 1 active lever presses0.80.91.90.71.30.21.4-0.3-1.11.1-0.4-1.3-0.61.20.80.2
Progressive ratio test 1 breakpoint0.60.71.50.61.20.31.2-0.4-1.01.0-0.3-1.2-0.61.00.60.2
Progressive ratio test 1 inactive lever presses0.50.63.11.40.40.40.3-1.3-0.10.10.0-0.10.6-0.0-0.11.8
Progressive ratio test 2 active lever presses0.20.30.80.10.90.40.8-0.5-0.60.60.1-0.7-0.50.40.0-0.0
Progressive ratio test 2 breakpoint0.40.40.90.30.80.10.9-0.2-0.90.9-0.3-1.0-0.80.70.4-0.2
Progressive ratio test 2 inactive lever presses0.70.81.90.61.20.41.4-0.5-1.21.2-0.2-1.4-0.70.90.60.0
Total sessions with >9 infusions1.51.65.3-0.12.32.01.2-2.30.1-0.11.6-0.60.9-0.0-1.01.0
Short access day 1 total inactive lever presses1.11.26.62.6-0.7-0.8-0.2-0.8-0.20.2-1.00.10.2-0.10.52.4
Short access day 10 total inactive lever presses1.51.64.40.5-0.70.5-1.1-1.21.5-1.50.81.52.1-1.5-0.91.9
Short access day 1 total infusions1.61.76.01.02.21.51.3-2.5-0.40.40.9-0.90.30.3-0.61.9
Short access day 10 total infusions0.30.41.61.3-0.1-0.60.3-0.0-0.50.5-0.8-0.40.30.40.80.8
Short access total infusions0.30.41.71.20.40.00.4-1.0-0.30.3-0.2-0.30.10.10.11.3
Short access day 1 locomotion0.90.92.90.71.71.11.2-1.7-0.40.40.6-0.80.10.5-0.31.2
Short access day 10 total locomotion0.50.61.5-0.91.20.91.0-0.1-0.40.40.6-0.71.10.40.3-0.8
Short access total locomotion0.90.93.3-0.31.81.41.2-1.2-0.20.21.0-0.71.20.2-0.20.3
Compulsive drug intake2.52.54.2-1.50.21.6-1.0-1.41.8-1.82.01.51.8-1.9-2.00.4
One hour access (0.3 mA shock)0.00.00.1-0.10.20.20.0-0.2-0.10.10.1-0.1-0.0-0.2-0.2-0.0
One hour access (shock baseline)1.11.22.00.20.5-0.71.00.9-1.41.4-1.0-1.4-1.41.41.2-1.1
Number of responses in last shaping day1.11.13.80.11.91.61.2-1.8-0.30.31.0-0.80.00.3-0.70.7
Context. condit. distance diff. score1.11.34.00.31.4-0.50.40.7-1.51.50.1-1.4-2.01.40.9-0.8
Locomotion velocity, session 10.80.92.60.4-1.3-0.4-1.10.01.0-1.0-0.21.21.6-1.1-0.20.9
Locomotion distance, session 10.50.62.30.6-1.0-1.5-0.91.5-0.30.3-0.80.10.00.31.0-0.3
Locomotion velocity, session 20.30.31.0-0.7-1.0-0.6-0.80.60.5-0.5-0.10.7-0.0-0.5-0.3-0.5
Locomotion distance, session 21.01.43.70.9-0.5-1.9-0.51.9-1.11.1-1.1-0.6-1.11.11.6-0.7
Locomotion velocity, session 30.20.20.5-0.20.50.70.1-0.70.4-0.40.60.20.7-0.3-0.50.3
Locomotion distance, session 31.61.74.0-1.30.20.8-1.4-0.81.6-1.62.01.40.9-1.4-1.80.1
Stereotopy head waving bouts, day 31.41.74.5-0.91.52.10.4-2.00.9-0.91.90.21.2-0.8-1.60.6
Stereotopy head waving duration, day 30.40.51.2-0.91.11.10.6-0.80.1-0.11.1-0.30.3-0.1-0.6-0.4
Locomotion velocity, session 70.10.20.6-0.30.8-0.1-0.30.3-0.20.20.7-0.3-0.50.3-0.0-0.5
Locomotion distance, session 70.30.31.20.4-0.5-1.1-0.51.0-0.20.2-0.6-0.1-0.40.40.7-0.3
Stereotopy head waving bouts, day 72.02.35.6-1.80.21.5-1.0-1.41.6-1.62.11.41.1-1.7-2.40.0
Stereotopy head waving duration, day 71.72.04.4-1.7-0.11.2-1.0-1.21.6-1.61.81.51.3-1.7-2.10.0
Locomotion velocity, session 80.60.73.11.8-0.2-1.4-0.70.7-0.50.5-0.8-0.2-0.70.51.00.7
Locomotion distance, session 81.11.73.70.70.2-1.8-0.41.9-1.41.4-0.7-1.0-1.81.41.5-1.0
Degree of sensitization distance2.12.14.51.7-0.5-1.70.71.5-1.51.5-2.1-1.2-1.31.62.1-0.1
Degree of sensitization stereotypy0.91.02.5-1.40.41.0-0.6-0.80.9-0.91.60.80.6-1.0-1.6-0.3
Condit. Reinf. active minus inactive responses1.11.25.9-0.82.10.4-1.1-0.60.2-0.22.4-0.0-1.1-0.1-1.4-0.4
Condit. Reinf. active-inactive response ratio1.01.04.80.01.7-0.7-0.40.6-0.90.90.9-0.9-2.21.00.1-0.8
Condit. Reinf. active responses1.01.25.0-1.11.40.7-1.1-0.80.8-0.82.20.5-0.3-0.7-1.7-0.2
Condit. Reinf. inactive responses1.72.13.9-0.5-1.30.6-1.4-0.91.9-1.90.72.01.9-1.9-1.51.0
Incentive salience index mean1.82.16.8-0.91.00.9-1.7-1.31.5-1.52.61.30.5-1.5-2.20.5
Condit. Reinf. lever presses2.83.76.2-0.7-0.41.4-1.8-1.92.4-2.42.12.21.9-2.4-2.51.5
Time in familiar zone, hab. session 10.60.51.8-1.3-0.4-0.1-0.90.20.7-0.70.80.8-0.2-0.7-0.9-0.8
Time in novel zone, hab. session 10.70.73.6-0.60.71.01.9-0.4-0.70.7-0.4-1.00.50.70.4-0.6
Total zone transitions, hab. session 10.30.41.50.2-1.2-0.9-0.01.0-0.20.2-1.10.1-0.00.20.8-0.3
Total locomotion distance, hab. session 10.20.30.80.1-0.8-0.60.20.8-0.20.2-0.9-0.10.40.20.8-0.3
Locomotion velocity, hab. session 10.30.51.20.6-1.1-1.0-0.21.0-0.20.2-1.10.10.40.21.00.1
Time in familiar zone, hab. session 20.60.61.90.0-1.1-0.7-1.40.40.9-0.90.11.10.6-0.9-0.30.3
Time in novel zone, hab. session 22.32.34.7-0.21.40.02.00.7-2.02.0-0.7-2.2-1.82.01.2-1.5
Total zone transitions, hab. session 20.40.61.6-0.4-1.3-1.0-1.11.10.5-0.5-0.20.80.7-0.40.2-0.5
Total locomotion distance, hab. session 20.50.61.90.8-1.1-1.4-0.71.2-0.20.2-0.90.20.40.21.00.1
Locomotion velocity, hab. session 20.50.71.91.1-1.2-1.4-0.71.1-0.10.1-1.00.30.40.21.10.4
Novel to familiar place preference ratio0.90.92.6-0.90.4-0.11.30.9-1.01.0-0.5-1.1-0.81.10.9-1.6
Novelty place preference1.21.22.9-0.80.2-0.31.41.2-1.21.2-0.8-1.3-0.91.21.1-1.7
Time in novel zone, NPP test1.11.23.2-1.20.50.21.80.7-1.11.1-0.5-1.3-0.51.10.9-1.7
Total zone transitions, NPP test0.60.93.01.3-1.3-1.6-1.71.00.3-0.3-0.60.80.0-0.30.60.8
Total locomotion distance, NPP test0.10.20.60.4-0.6-0.8-0.60.7-0.00.0-0.30.20.20.00.50.0
Locomotion velocity, NPP test0.50.72.11.4-0.7-1.4-1.21.0-0.20.2-0.60.3-0.30.20.80.6
Pavlov. Cond. lever latency0.81.03.0-0.6-0.7-1.10.21.7-0.80.8-1.1-0.5-0.90.81.0-1.6
Pavlov. Cond. magazine entry latency0.60.72.9-0.61.11.71.1-1.40.2-0.21.0-0.40.6-0.1-0.70.2
Pavlov. Cond. change in total contacts1.51.63.10.50.11.1-0.9-1.71.4-1.41.21.21.6-1.4-1.31.8
Pavlov. Cond. index score0.81.13.30.11.11.60.2-1.80.7-0.71.40.20.9-0.6-1.01.1
Pavlov. Cond. latency score0.60.72.10.40.81.2-0.1-1.50.6-0.61.10.30.7-0.6-0.81.2
Pavlov. Cond. lever contacts0.80.93.20.70.71.30.2-1.80.7-0.70.80.31.0-0.6-0.81.6
Pavlov. Cond. magazine entry number1.31.65.50.4-1.6-2.3-0.92.2-0.60.6-1.60.1-1.20.61.2-0.9
Pavlov. Cond. intertrial magazine entries0.80.92.61.20.5-0.2-1.6-0.90.8-0.81.00.80.3-0.7-0.91.6
Pavlov. Cond. lever-magazine prob. diff.0.91.13.80.41.41.70.6-1.90.4-0.41.2-0.10.8-0.4-0.81.3
Pavlov. Cond. response bias1.21.55.0-0.31.32.21.0-2.20.7-0.71.3-0.01.2-0.6-1.21.0
Bone: apparent density1.82.96.9-1.6-2.60.4-1.1-0.22.2-2.20.02.32.3-2.2-1.40.2
Bone surface2.74.78.9-0.6-1.81.1-1.8-1.62.9-2.91.22.83.0-2.8-2.21.8
Bone volume2.74.58.7-0.4-2.11.0-1.7-1.52.8-2.80.72.83.0-2.7-2.01.8
Bone: connectivity density3.35.29.7-2.2-2.80.8-1.8-0.63.0-3.00.83.12.8-2.9-2.20.3
Bone: cortical apparent density0.70.95.0-2.20.90.80.40.1-0.00.01.4-0.3-0.3-0.1-0.8-1.6
Bone: cortical area0.30.41.51.2-0.3-1.2-1.10.6-0.10.1-0.20.3-0.30.10.30.5
Bone: cortical porosity0.80.92.61.60.7-0.40.6-0.1-1.11.1-0.8-1.0-1.21.10.80.6
Bone: cortical porosity0.60.63.31.80.8-0.4-0.1-0.3-0.70.7-0.3-0.6-1.00.70.41.1
Bone: cortical thickness1.01.73.10.71.3-1.10.31.2-1.71.7-0.2-1.5-1.81.71.2-0.9
Bone: cortical thickness4.75.513.2-0.9-0.9-2.51.13.6-2.42.4-2.4-1.8-2.22.42.7-3.3
Bone: cortical tissue density0.70.95.0-2.20.90.80.2-0.10.2-0.21.6-0.1-0.2-0.2-1.0-1.5
Bone: elastic displacement0.30.32.00.41.40.50.0-0.6-0.20.21.0-0.40.50.1-0.20.5
Bone: elastic work0.60.82.40.81.6-0.10.70.2-1.31.30.2-1.3-0.31.20.9-0.1
Bone: endosteal estimation0.40.82.41.1-1.5-1.5-0.91.2-0.00.0-1.20.4-0.1-0.00.90.3
Bone: endosteal perimeter0.81.75.62.0-1.3-1.2-2.4-0.01.0-1.0-0.11.50.4-1.0-0.31.9
Bone: final force0.50.82.71.6-0.7-1.3-0.30.8-0.60.6-1.3-0.2-0.30.51.20.6
Bone: final moment0.40.72.21.5-0.6-1.3-0.30.9-0.60.6-1.1-0.3-0.30.61.10.4
Bone: marrow area0.40.82.41.1-1.5-1.5-0.81.2-0.10.1-1.30.4-0.20.10.90.2
Bone: maximum diameter0.30.62.41.20.2-0.4-1.5-0.50.6-0.60.80.8-0.2-0.5-0.61.2
Bone: maximum force0.30.53.01.7-0.3-0.9-0.40.3-0.40.4-0.9-0.1-0.10.40.80.9
Bone: maximum moment0.30.52.61.6-0.2-1.0-0.40.4-0.40.4-0.7-0.1-0.10.40.80.8
Bone: minimum diameter0.71.33.61.3-1.9-1.4-1.70.70.8-0.8-0.91.30.6-0.80.31.0
Bone: periosteal estimation0.51.03.21.3-1.5-1.8-1.51.20.1-0.1-1.00.7-0.3-0.10.70.4
Bone: periosteal perimeter0.61.15.31.5-0.7-1.4-2.30.50.6-0.60.31.1-0.1-0.5-0.21.1
Bone: post-yield work0.30.42.60.2-1.6-0.5-0.30.50.4-0.4-1.00.60.3-0.40.30.2
Bone: stiffness0.81.35.02.2-1.0-1.4-0.10.7-0.70.7-2.0-0.3-0.70.71.40.9
Bone: tissue strength0.30.31.00.91.00.3-0.1-0.7-0.20.20.7-0.4-0.40.2-0.10.8
Bone: trabecular number4.06.211.1-2.3-2.41.8-1.2-1.63.3-3.31.23.13.3-3.2-2.70.7
Bone: trabecular spacing2.93.77.91.32.1-0.91.31.1-2.62.6-0.6-2.5-2.82.51.9-0.9
Bone: trabecular thickness0.40.51.8-0.3-1.40.1-0.0-0.20.8-0.8-0.70.81.3-0.7-0.20.4
Bone: trabecular tissue density2.02.74.80.81.0-0.62.00.8-2.12.1-1.6-2.2-2.02.11.9-0.8
Breakpoint value in progressive ratio session5.25.811.72.5-0.8-3.00.92.6-2.72.7-3.2-1.9-2.12.63.4-0.4
Distance traveled before self-admin0.40.41.01.00.40.11.0-0.5-0.70.7-0.4-0.8-0.70.50.30.6
Distance traveled after self-admin0.30.31.30.50.30.41.2-0.9-0.50.5-0.2-0.7-0.20.1-0.10.4
Delta time in closed arm before/after self-admin0.60.52.1-0.81.50.80.6-0.3-0.30.30.7-0.6-1.00.6-0.4-0.8
Delta time in open arm before/after self-admin2.92.88.32.2-2.4-2.9-1.62.2-0.30.3-2.30.5-0.20.42.00.8
Diff in mean of infusions in LGA sessions0.20.30.80.4-0.6-0.9-0.30.8-0.20.2-0.80.1-0.00.40.7-0.1
Extinction: sum of active levers before priming1.11.14.3-1.52.11.21.1-0.2-0.30.31.1-0.90.00.8-0.2-1.3
Active lever presses in extinction session 61.11.12.1-0.50.61.5-0.4-1.50.8-0.81.40.61.4-1.1-1.20.8
Delta distance traveled before/after self-admin0.10.10.2-0.50.20.30.2-0.20.2-0.20.30.00.5-0.1-0.2-0.2
Delta ambulatory time before/after self-admin0.50.51.3-0.9-0.30.5-0.5-0.30.8-0.80.70.81.1-0.9-0.7-0.2
Time in closed arm before self-admin1.21.42.8-1.3-0.51.3-0.2-1.11.3-1.31.31.11.7-1.4-1.50.0
Time in closed arm after self-admin0.30.40.9-0.90.50.90.3-0.70.3-0.30.80.1-0.5-0.1-1.0-0.3
Time in open arm before self-admin0.50.52.1-0.61.40.70.7-0.4-0.50.50.4-0.8-0.80.4-0.3-0.7
Time in open arm after self-admin0.70.81.80.80.1-1.00.21.1-1.01.0-1.1-0.8-0.51.01.3-0.3
Sum of active levers in priming session hrs 5-60.40.41.4-0.2-0.7-1.1-0.61.2-0.00.0-0.60.3-0.00.20.6-0.7
Time to tail flick, vehicle, before self-admin0.20.20.60.2-0.8-0.2-0.1-0.20.5-0.5-0.20.60.5-0.3-0.30.7
Time to tail flick, vehicle, after self-admin1.61.74.40.4-1.6-2.1-0.72.0-0.50.5-1.80.2-2.00.81.0-0.8
Time to tail flick, test, before self-admin1.00.91.81.20.8-0.20.9-0.3-1.31.3-0.7-1.3-1.30.90.80.4
Time to tail flick, test, after self-admin0.20.20.70.2-0.5-0.6-0.30.5-0.10.1-0.50.1-0.80.30.2-0.1
Delta time to tail flick, vehicle, before/after SA0.50.51.80.5-0.8-1.1-0.90.8-0.20.2-0.80.3-1.30.20.4-0.1
Delta time to tail flick, test, before/after SA0.10.10.4-0.7-0.10.0-0.40.20.3-0.30.30.3-0.2-0.1-0.3-0.5
Ambulatory time before self-admin0.90.92.11.40.5-0.21.3-0.2-1.21.2-0.9-1.2-0.90.91.00.6
Ambulatory time after self-admin0.20.20.50.7-0.4-0.10.6-0.5-0.40.4-0.5-0.30.0-0.20.20.5
Total heroin consumption0.91.12.70.3-0.2-1.30.11.7-1.11.1-1.2-0.8-0.51.21.6-1.0
Area under the delay curve0.30.31.2-1.10.70.70.1-0.20.2-0.20.70.10.2-0.2-0.6-0.7
Delay disc. indifference point, 0s delay0.70.73.00.1-0.60.3-0.6-0.51.0-1.00.21.11.7-1.0-0.51.1
Delay disc. indifference point, 16s delay1.01.01.8-0.10.7-0.31.01.0-1.31.3-0.7-1.3-1.01.21.1-1.2
Delay disc. indifference point, 2s delay0.50.61.5-1.11.11.20.9-0.6-0.00.00.9-0.5-0.50.2-0.6-0.8
Delay disc. indifference point, 24s delay0.30.31.6-0.01.30.4-0.2-0.1-0.30.30.6-0.4-0.90.4-0.20.0
Delay disc. indifference point, 4s delay1.31.42.8-1.7-0.41.2-0.2-0.81.3-1.31.11.21.7-1.3-1.5-0.3
Delay disc. indifference point, 8s delay0.40.41.8-1.31.10.6-0.0-0.10.2-0.20.90.00.2-0.0-0.7-0.9
Delay discount exponential model param0.40.41.91.4-0.7-0.8-0.00.2-0.30.3-0.9-0.1-0.10.20.80.8
Delay discount hyperbolic model param0.50.62.71.6-0.7-0.9-0.00.2-0.40.4-1.0-0.2-0.20.30.91.0
Fecal boli incidents, locomotor time 11.51.75.81.7-1.4-0.5-1.9-0.71.1-1.1-0.11.50.2-1.2-0.52.4
Change in fecal boli incidents, locomotor task1.81.75.3-2.30.01.2-0.3-0.71.3-1.31.51.11.7-1.3-1.6-0.9
Time >=10cm from walls, locomotor time 10.30.31.5-1.2-0.70.00.50.2-0.00.0-0.10.0-0.4-0.2-0.4-1.1
Bouts of movement, locomotor time 10.50.61.4-0.70.51.2-0.0-1.10.6-0.61.00.40.7-0.8-1.20.2
Total resting periods, locomotor time 10.91.02.7-1.00.91.60.1-1.40.6-0.61.40.30.7-0.9-1.50.2
Rest time, locomotor task time 10.60.72.0-0.31.11.3-0.1-1.40.3-0.31.30.10.2-0.8-1.20.5
Distance moved, locomotor task time 11.01.12.50.5-0.4-1.10.91.4-0.90.9-1.5-0.9-0.51.41.6-0.8
Vertical activity count, locomotor time 12.02.16.31.5-2.5-2.3-0.71.9-0.10.1-2.40.4-0.90.61.50.1
Time >=10cm from walls, locomotor time 20.50.62.20.40.70.31.5-0.3-0.90.9-0.6-1.1-0.40.90.5-0.1
Bouts of movement, locomotor time 20.50.62.1-1.50.90.91.0-0.2-0.10.10.6-0.50.00.2-0.5-1.3
Total resting periods, locomotor time 20.30.31.2-1.10.40.50.8-0.0-0.10.10.3-0.4-0.20.1-0.3-1.1
Rest time, locomotor task time 20.10.10.6-0.3-0.8-0.2-0.40.10.3-0.3-0.00.5-0.3-0.4-0.30.0
Distance moved, locomotor task time 21.21.43.30.61.4-0.21.60.3-1.51.5-0.8-1.8-0.71.61.3-0.5
Vertical activity count, locomotor time 21.11.23.21.5-0.9-1.8-0.51.4-0.70.7-1.8-0.2-0.60.71.50.3
Weight adjusted by age0.40.41.2-0.40.90.51.1-0.2-0.50.50.1-0.7-1.00.6-0.2-0.9
Seeking ratio, delayed vs. immediate footshock1.21.44.6-2.11.40.61.40.5-0.70.70.6-1.2-0.71.10.2-2.0
Locomotion in novel chamber2.42.96.9-0.0-0.2-1.70.82.6-1.81.8-1.8-1.5-1.71.92.2-2.0
Locomotion in novel chamber post-restriction0.50.54.30.1-0.30.60.2-0.50.6-0.60.30.52.1-0.6-0.10.8
Progressive ratio0.40.51.4-0.2-1.1-1.1-0.71.20.1-0.1-0.50.2-0.80.20.3-0.7
Food seeking constrained by brief footshock1.21.43.71.1-1.6-0.5-1.9-0.11.2-1.20.21.60.9-1.4-0.61.4
Seeking ratio, punishment vs. effort0.70.92.61.2-0.10.6-0.7-1.20.7-0.70.40.81.3-1.1-0.61.6
Run reversals in cocaine runway, females3.63.55.82.40.7-1.51.01.1-2.32.3-2.0-2.1-2.32.32.40.3
Run reversals in cocaine runway, males0.60.62.3-1.20.20.71.1-0.2-0.50.50.4-0.7-0.80.1-0.5-1.5
Latency to leave start box in cocaine runway2.02.24.21.3-0.3-1.80.41.6-1.71.7-1.9-1.2-1.61.52.0-0.5
Latency to leave start box in cocaine runway, F1.11.22.41.50.3-0.71.10.4-1.41.4-1.3-1.2-0.71.41.50.3
Latency to leave start box in cocaine runway, M2.42.37.81.5-1.6-2.8-1.62.2-0.80.8-1.90.2-1.30.51.7-0.1
Cd content in liver0.40.41.8-0.70.50.1-1.00.20.4-0.41.30.4-0.5-0.3-0.7-0.5
Co content in liver1.31.55.7-1.02.41.80.3-1.50.2-0.22.3-0.30.1-0.2-1.30.0
Cu content in liver0.40.41.7-0.10.9-0.4-0.20.5-0.70.70.4-0.6-1.30.70.2-0.7
Fe content in liver1.61.85.40.20.51.90.0-2.31.3-1.31.10.91.4-1.4-1.51.7
K content in liver0.20.20.70.90.4-0.10.30.1-0.40.4-0.3-0.40.80.40.80.3
Mg content in liver0.30.31.30.71.00.50.2-0.6-0.10.10.5-0.31.10.10.20.7
Mn content in liver0.30.42.11.40.0-0.8-0.70.4-0.30.3-0.3-0.00.20.20.60.7
Na content in liver0.20.21.10.3-0.7-0.00.60.1-0.10.1-1.0-0.10.80.00.60.2
Rb content in liver0.10.10.30.30.00.2-0.5-0.40.4-0.40.40.40.5-0.4-0.30.5
Se content in liver2.12.56.81.4-0.30.9-1.4-1.91.7-1.70.81.61.7-1.8-1.42.6
Sr content in liver0.50.51.51.20.8-0.4-0.10.4-0.80.8-0.2-0.7-0.70.81.00.3
Zn content in liver0.70.82.00.00.6-1.00.01.1-1.21.2-0.3-0.9-1.41.10.7-1.0