Prpf40b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000113722 0.02 0.02 8.8e-03 0.02 0.01 0.01 0.01 6.4e-03 1.4e-02 1.3e-02 8.5e-03
2 Adipose alternative TSS ENSRNOT00000113677 0.09 0.1 7.9e-08 0.06 0.06 0.06 0.06 9.6e-08 2.4e-07 9.7e-08 1.0e-07
3 Adipose alternative TSS ENSRNOT00000113722 0.09 0.1 5.1e-08 0.07 0.06 0.07 0.07 6.5e-08 1.6e-07 6.7e-08 7.0e-08
4 Adipose gene expression ENSRNOG00000052539 0.17 0.13 0.0e+00 0.14 0.14 0.14 0.14 3.4e-15 1.1e-15 2.8e-15 1.5e-15
5 Adipose mRNA stability ENSRNOG00000052539 0.03 0.03 3.2e-03 0.01 0.01 0.01 0.01 7.7e-03 1.1e-02 8.4e-03 1.1e-02
6 Eye alternative TSS ENSRNOT00000091306 0.31 0.22 1.3e-03 0.19 0.18 0.12 0.17 6.6e-04 9.3e-04 6.6e-03 1.2e-03
7 Eye alternative TSS ENSRNOT00000113677 0.35 0.25 1.2e-03 0.18 0.17 0.1 0.17 8.5e-04 1.5e-03 1.5e-02 1.2e-03
8 NAcc intron excision ratio chr7:130452523:130452696 0.04 0.03 1.4e-03 0.03 0.03 0.03 0.03 1.9e-03 2.3e-03 3.3e-03 2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail4.113.414.33.6-3.63.6-3.8-3.7-3.63.63.7
BMI without tail0.10.20.40.6-0.60.50.20.10.3-0.30.2
Body weight5.523.125.54.4-4.44.6-5.0-5.0-4.94.95.0
Epididymis fat weight0.10.20.50.0-0.00.1-0.6-0.6-0.70.70.4
Glucose0.30.41.2-0.90.9-1.1-0.00.0-0.10.1-0.4
Heart weight0.10.10.30.2-0.20.6-0.3-0.3-0.20.20.3
Left kidney weight0.71.93.71.6-1.61.9-1.1-1.1-1.01.01.5
Right kidney weight2.46.78.02.3-2.32.6-2.7-2.6-2.62.62.8
Tail length0.10.20.3-0.20.2-0.00.60.50.6-0.6-0.3
Length with tail1.86.87.82.4-2.42.6-2.7-2.7-2.72.72.8
Length without tail6.414.016.83.2-3.23.4-4.1-4.0-4.14.13.8
Liver weight, left1.52.53.01.4-1.41.3-1.7-1.7-1.61.61.6
Liver weight, right1.52.42.81.5-1.51.4-1.6-1.6-1.61.61.7
Parametrial fat weight1.93.64.9-1.41.4-1.52.12.22.1-2.1-2.1
Retroperitoneal fat weight0.82.83.5-1.91.9-1.81.51.71.3-1.3-1.8
Intraocular pressure6.59.211.0-2.72.7-2.73.33.23.3-3.3-3.0
Extensor digitorum longus weight4.116.420.14.3-4.34.5-4.0-3.9-3.63.64.2
Soleus weight0.82.43.61.7-1.71.9-1.4-1.4-1.31.31.5
Tibialis anterior weight1.75.910.83.2-3.23.3-1.7-1.8-1.41.42.4
Tibia length5.515.620.43.2-3.23.2-4.4-4.2-4.54.54.0
Number of licking bursts1.11.32.2-1.41.4-1.50.91.00.8-0.8-1.3
Food consumed during 24 hour testing period1.72.02.31.4-1.41.2-1.5-1.4-1.51.51.4
Times rat made contact with spout0.10.10.2-0.00.0-0.10.40.40.4-0.4-0.3
Mean time between licks in bursts0.00.00.0-0.10.1-0.10.10.10.1-0.1-0.0
Mean num. licks in bursts0.40.51.11.0-1.01.1-0.3-0.4-0.10.10.7
Std. dev. time between licks in bursts1.31.62.0-1.31.3-1.41.31.31.1-1.1-1.3
Water consumed over 24 hours0.00.00.1-0.30.3-0.3-0.1-0.1-0.20.2-0.1
Indifference point 0 sec4.47.010.7-3.33.3-3.22.22.22.0-2.0-2.6
Indifference point AUC0.30.40.6-0.50.5-0.50.60.80.5-0.5-0.8
Indifference point function ln k4.76.77.72.7-2.72.8-2.5-2.6-2.42.42.7
Indifference point function log k4.76.77.72.7-2.72.8-2.5-2.6-2.42.42.7
Delay discounting total patch changes 0 sec4.16.610.0-3.23.2-3.12.12.21.9-1.9-2.6
Delay discounting total patch changes 12 sec4.45.88.7-3.03.0-2.92.02.11.8-1.8-2.4
Delay discounting total patch changes 18 sec6.28.111.3-3.23.2-3.42.62.72.3-2.3-3.0
Delay discounting total patch changes 24 sec3.74.66.5-2.52.5-2.51.92.01.6-1.6-2.2
Delay discounting total patch changes 6 sec4.97.511.9-3.43.4-3.32.32.32.0-2.0-2.6
Delay discounting time to switch 0 sec2.33.54.3-1.91.9-2.11.91.91.8-1.8-1.8
Delay discounting water rate 0 sec2.94.65.62.2-2.22.4-2.1-2.0-2.12.12.0
Delay discounting water rate 12 sec3.45.16.22.0-2.02.0-2.4-2.4-2.52.52.1
Delay discounting water rate 18 sec0.30.40.60.8-0.80.8-0.6-0.6-0.50.50.7
Delay discounting water rate 24 sec4.15.76.82.6-2.62.5-2.3-2.3-2.22.22.4
Delay discounting water rate 6 sec4.87.08.93.0-3.02.9-2.5-2.4-2.42.42.5
Locomotor activity1.11.72.1-1.31.3-0.81.51.41.4-1.4-1.2
Locomotor testing distance3.05.05.6-2.42.4-1.82.42.32.2-2.2-2.2
Locomotor testing rearing2.23.54.0-1.91.9-1.82.01.81.9-1.9-1.8
Light reinforcement 12.03.75.2-1.31.3-1.32.32.22.3-2.3-2.0
Light reinforcement 20.40.61.4-0.10.1-0.11.00.91.2-1.2-0.4
Reaction time number correct1.52.22.81.3-1.31.2-1.7-1.7-1.71.71.4
Reaction time mean minus median7.810.212.0-2.72.7-3.03.43.53.4-3.4-3.4
Reaction time mean minus median AUC5.67.18.2-2.32.3-2.62.82.92.8-2.8-2.8
Reaction time num false alarms1.52.12.6-1.31.3-1.41.51.61.4-1.4-1.6
Reaction time num false alarms AUC2.02.83.4-1.41.4-1.51.81.91.7-1.7-1.8
Reaction time trials correct on left1.52.22.81.3-1.31.2-1.7-1.7-1.71.71.4
Reaction time trials on left1.21.82.31.1-1.11.0-1.5-1.5-1.51.51.3
Reaction time mean0.81.11.2-1.01.0-1.11.11.11.0-1.0-1.1
Reaction time mean AUC0.40.60.6-0.70.7-0.80.80.80.7-0.7-0.8
Median of all reaction times0.00.00.0-0.20.2-0.10.00.0-0.10.1-0.0
Reaction time omissions8.912.014.0-3.13.1-3.13.73.63.7-3.7-3.5
Reaction time false alarm rate2.43.44.3-1.51.5-1.62.02.12.0-2.0-1.9
Reaction time premature initiation rate5.47.210.1-2.02.0-2.03.13.03.2-3.2-2.6
Reaction time premature initiations2.13.04.5-1.21.2-1.22.12.02.1-2.1-1.7
Std. dev. reaction times6.18.49.3-2.72.7-2.93.03.03.0-3.0-3.0
Reaction time trials completed1.21.82.31.1-1.11.0-1.5-1.5-1.51.51.3
Reaction time trials AUC2.02.83.51.4-1.41.3-1.8-1.9-1.91.91.6
Social response proportion0.10.10.2-0.30.3-0.00.40.50.5-0.5-0.4
Social responses7.39.411.0-2.72.7-2.63.33.33.3-3.3-3.2
Social time0.20.30.90.7-0.70.9-0.1-0.30.2-0.20.4
Conditioned locomotion0.00.00.1-0.10.1-0.2-0.2-0.1-0.20.2-0.1
Cocaine response after cond. corrected0.00.00.00.1-0.10.10.00.00.0-0.00.1
Cocaine response after cond. not corrected0.30.40.6-0.40.4-0.40.70.70.7-0.7-0.5
Cocaine response before conditioning2.93.54.1-1.61.6-1.72.02.02.0-2.0-1.9
Saline control response0.10.10.2-0.20.2-0.3-0.4-0.3-0.50.50.0
Condit. Reinf. active minus inactive responses0.20.30.91.0-1.00.7-0.00.00.1-0.10.2
Condit. Reinf. active-inactive response ratio0.40.40.80.9-0.90.50.40.40.6-0.6-0.1
Condit. Reinf. active responses0.10.10.20.3-0.30.20.40.40.4-0.4-0.2
Condit. Reinf. inactive responses0.60.70.9-0.90.9-0.80.90.80.8-0.8-0.8
Condit. Reinf. lever presses0.00.00.00.1-0.1-0.0-0.0-0.0-0.10.1-0.1
Condit. Reinf. lever reinforcers received0.30.40.6-0.10.1-0.30.80.80.8-0.8-0.7
Pavlov. Cond. lever latency0.40.51.70.9-0.91.3-0.3-0.3-0.10.10.7
Pavlov. Cond. magazine entry latency0.60.71.3-0.30.3-0.6-1.0-1.0-1.11.10.4
Pavlov. Cond. change in total contacts0.81.11.60.8-0.80.6-1.2-1.2-1.31.30.9
Pavlov. Cond. index score0.40.51.0-0.70.7-1.0-0.6-0.5-0.80.8-0.1
Pavlov. Cond. latency score0.40.51.0-0.60.6-1.0-0.6-0.6-0.80.8-0.0
Pavlov. Cond. lever contacts0.50.61.7-0.90.9-1.30.50.50.4-0.4-0.8
Pavlov. Cond. magazine entry number1.01.22.60.1-0.10.31.41.41.6-1.6-0.8
Pavlov. Cond. intertrial magazine entries3.74.86.8-1.51.5-1.42.62.62.6-2.6-2.2
Pavlov. Cond. lever-magazine prob. diff.0.40.61.1-0.40.4-0.7-0.9-0.8-1.01.00.2
Pavlov. Cond. response bias0.20.31.1-0.70.7-1.00.20.20.1-0.1-0.5
Conditioned reinforcement - actives1.41.42.1-0.80.8-1.01.31.21.5-1.5-1.1
Conditioned reinforcement - inactives2.22.53.0-1.31.3-1.51.71.71.7-1.7-1.5
Conditioned locomotion0.50.61.2-0.20.2-0.80.71.10.9-0.9-0.8
Intermittent access intake day 1-15 change0.90.91.6-0.30.3-0.31.21.11.3-1.3-1.1
Intermittent access intake escalation0.60.61.10.0-0.00.11.00.91.1-1.1-0.7
Intermittent access intake escalation 21.01.01.8-0.30.3-0.41.31.11.4-1.4-0.9
Intermitt. access day 1 inactive lever presses1.31.42.6-0.40.4-0.81.51.31.6-1.6-1.0
Intermitt. access day 15 inactive lever presses0.70.81.60.0-0.0-0.21.01.31.2-1.2-0.8
Intermitt. access escalation Index0.60.51.2-1.11.1-0.90.50.40.3-0.3-0.4
Intermittent access day 1 total infusions1.21.31.7-1.11.1-1.11.21.21.3-1.3-1.0
Intermittent access day 15 total infusions2.32.63.6-1.31.3-1.21.91.71.9-1.9-1.6
Intermittent access terminal intake (last 3 days)2.52.73.7-1.21.2-1.31.91.81.9-1.9-1.6
Intermittent access total infusions2.32.53.5-1.21.2-1.31.81.71.9-1.9-1.4
Intermittent access day 1 locomotion1.01.11.5-0.90.9-1.11.01.21.0-1.0-0.9
Intermittent access day 15 total locomotion1.71.92.6-1.01.0-1.21.41.61.6-1.6-1.4
Intermittent access total locomotion4.04.55.3-2.02.0-2.22.12.32.2-2.2-2.1
Intermittent access standard deviation0.30.40.70.3-0.30.20.70.80.8-0.8-0.4
Cocaine induced anxiety1.41.62.61.2-1.21.2-1.1-1.6-1.11.11.6
Post-drug Anxiety5.66.28.22.2-2.22.5-2.4-2.8-2.42.42.9
Baseline Anxiety0.80.81.00.6-0.61.0-1.0-0.9-1.01.00.9
Lifetime Intake2.62.93.6-1.41.4-1.61.91.81.9-1.9-1.6
Incentive Sensitization - Responses0.10.10.20.2-0.20.5-0.0-0.30.1-0.10.4
Incentive Sensitization - Breakpoint0.00.00.10.1-0.10.30.1-0.10.2-0.20.3
Progressive ratio test 1 active lever presses6.66.88.5-2.92.9-2.92.52.42.4-2.4-2.4
Progressive ratio test 1 breakpoint5.96.07.3-2.72.7-2.72.42.22.3-2.3-2.3
Progressive ratio test 1 inactive lever presses3.03.24.7-1.41.4-1.52.01.82.2-2.2-1.6
Progressive ratio test 2 active lever presses2.52.73.2-1.61.6-1.51.71.61.8-1.8-1.4
Progressive ratio test 2 breakpoint3.03.44.1-1.81.8-1.62.01.82.0-2.0-1.6
Progressive ratio test 2 inactive lever presses2.12.43.6-1.21.2-1.21.71.81.9-1.9-1.3
Total sessions with >9 infusions1.41.51.8-1.11.1-1.41.31.21.3-1.3-1.3
Short access day 1 total inactive lever presses1.51.62.2-1.01.0-1.11.41.51.4-1.4-1.2
Short access day 10 total inactive lever presses0.10.10.10.3-0.3-0.10.30.40.4-0.4-0.3
Short access day 1 total infusions0.30.30.6-0.70.7-0.70.40.20.4-0.4-0.5
Short access day 10 total infusions2.02.23.4-1.61.6-1.91.31.41.3-1.3-1.5
Short access total infusions1.11.31.9-1.21.2-1.41.10.91.0-1.0-1.1
Short access day 1 locomotion0.20.30.6-0.40.4-0.80.50.50.5-0.5-0.4
Short access day 10 total locomotion0.20.30.8-0.30.3-0.90.40.70.4-0.4-0.2
Short access total locomotion0.60.71.3-0.50.5-1.20.80.90.9-0.9-0.8
Compulsive drug intake1.61.62.31.5-1.51.5-1.1-1.2-1.21.21.0
One hour access (0.3 mA shock)0.20.30.60.4-0.40.30.60.50.8-0.8-0.2
One hour access (shock baseline)0.20.20.50.1-0.1-0.10.60.50.7-0.7-0.1
Number of responses in last shaping day0.10.10.30.6-0.60.1-0.1-0.4-0.00.00.3
Context. condit. distance diff. score0.10.20.30.3-0.30.3-0.5-0.5-0.50.50.5
Locomotion velocity, session 12.42.54.5-2.12.1-2.11.21.11.1-1.1-1.4
Locomotion distance, session 12.63.43.6-1.91.9-1.81.81.81.9-1.9-1.8
Locomotion velocity, session 20.20.20.3-0.40.4-0.50.50.50.4-0.4-0.5
Locomotion distance, session 22.43.44.1-2.02.0-2.01.81.81.7-1.7-1.9
Locomotion velocity, session 34.45.15.6-2.32.3-2.32.22.22.1-2.1-2.4
Locomotion distance, session 33.84.25.7-1.61.6-1.62.32.42.2-2.2-2.2
Stereotopy head waving bouts, day 30.60.71.80.1-0.10.2-1.0-0.9-1.31.30.6
Stereotopy head waving duration, day 30.30.40.8-0.10.1-0.1-0.7-0.7-0.90.90.4
Locomotion velocity, session 71.31.42.9-1.71.7-1.70.70.80.4-0.4-1.1
Locomotion distance, session 72.83.55.2-2.22.2-2.31.71.71.4-1.4-1.9
Stereotopy head waving bouts, day 70.70.81.20.7-0.70.7-0.9-0.8-1.11.10.8
Stereotopy head waving duration, day 71.01.31.41.1-1.11.1-1.2-1.1-1.21.21.1
Locomotion velocity, session 80.10.20.4-0.60.6-0.60.00.00.0-0.0-0.4
Locomotion distance, session 81.21.82.2-1.51.5-1.51.31.21.3-1.3-1.3
Degree of sensitization distance0.20.20.4-0.10.1-0.1-0.6-0.6-0.70.70.4
Degree of sensitization stereotypy0.30.30.70.8-0.80.8-0.4-0.3-0.30.30.5
Condit. Reinf. active minus inactive responses0.10.10.1-0.30.3-0.30.20.20.2-0.2-0.2
Condit. Reinf. active-inactive response ratio0.20.20.30.3-0.30.3-0.5-0.5-0.60.60.5
Condit. Reinf. active responses0.70.81.0-1.01.0-1.00.90.90.8-0.8-0.9
Condit. Reinf. inactive responses2.83.33.6-1.81.8-1.71.91.81.9-1.9-1.9
Incentive salience index mean0.00.00.0-0.10.1-0.0-0.1-0.1-0.10.10.1
Condit. Reinf. lever presses0.20.30.50.7-0.70.7-0.4-0.4-0.30.30.6
Time in familiar zone, hab. session 10.10.10.30.1-0.10.10.40.40.5-0.5-0.3
Time in novel zone, hab. session 10.10.10.30.1-0.10.1-0.5-0.4-0.50.50.3
Total zone transitions, hab. session 10.20.30.5-0.40.4-0.40.60.60.7-0.7-0.5
Total locomotion distance, hab. session 10.10.20.4-0.60.6-0.6-0.1-0.0-0.20.2-0.2
Locomotion velocity, hab. session 10.10.10.3-0.50.5-0.5-0.2-0.1-0.30.3-0.1
Time in familiar zone, hab. session 20.91.01.81.3-1.31.3-0.7-0.8-0.60.60.9
Time in novel zone, hab. session 21.01.02.0-1.41.4-1.40.60.60.5-0.5-0.9
Total zone transitions, hab. session 20.30.40.4-0.60.6-0.60.60.60.6-0.6-0.6
Total locomotion distance, hab. session 20.20.30.5-0.70.7-0.70.30.30.1-0.1-0.5
Locomotion velocity, hab. session 20.10.10.3-0.50.5-0.50.20.2-0.10.1-0.3
Novel to familiar place preference ratio1.41.51.91.0-1.00.9-1.4-1.4-1.31.31.2
Novelty place preference0.90.91.30.7-0.70.6-1.1-1.1-1.11.11.0
Time in novel zone, NPP test0.70.71.10.5-0.50.4-1.0-1.0-1.01.00.8
Total zone transitions, NPP test2.02.84.1-2.02.0-2.01.51.41.4-1.4-1.6
Total locomotion distance, NPP test2.33.24.7-2.22.2-2.11.61.61.3-1.3-1.9
Locomotion velocity, NPP test1.42.03.1-1.81.8-1.71.21.21.0-1.0-1.5
Pavlov. Cond. lever latency0.10.20.2-0.40.4-0.4-0.4-0.5-0.40.40.1
Pavlov. Cond. magazine entry latency0.40.51.21.0-1.01.1-0.2-0.2-0.00.00.6
Pavlov. Cond. change in total contacts0.50.51.31.1-1.11.1-0.1-0.1-0.00.00.5
Pavlov. Cond. index score0.30.30.90.9-0.91.0-0.0-0.0-0.00.00.3
Pavlov. Cond. latency score0.20.30.70.8-0.80.80.10.10.0-0.00.2
Pavlov. Cond. lever contacts0.40.40.80.3-0.30.30.80.80.9-0.9-0.4
Pavlov. Cond. magazine entry number0.10.10.3-0.50.5-0.6-0.1-0.1-0.20.2-0.2
Pavlov. Cond. intertrial magazine entries2.02.45.2-2.32.3-2.20.80.80.6-0.6-1.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.41.1-1.11.2-0.4-0.3-0.30.30.6
Pavlov. Cond. response bias0.10.10.30.5-0.50.50.30.30.3-0.30.1
Bone: apparent density9.315.418.83.4-3.43.4-4.3-4.1-4.34.34.0
Bone surface11.019.322.73.9-3.93.9-4.7-4.6-4.84.84.5
Bone volume9.115.416.83.7-3.73.8-4.1-3.9-4.14.13.9
Bone: connectivity density6.09.412.82.4-2.42.3-3.5-3.3-3.63.63.1
Bone: cortical apparent density0.20.20.4-0.40.4-0.30.60.60.5-0.5-0.5
Bone: cortical area7.511.414.22.8-2.82.9-3.7-3.6-3.83.83.4
Bone: cortical porosity0.30.30.60.1-0.1-0.00.70.60.8-0.8-0.4
Bone: cortical porosity0.50.51.0-0.20.2-0.30.90.91.0-1.0-0.7
Bone: cortical thickness2.33.85.21.5-1.51.6-2.2-2.1-2.32.31.9
Bone: cortical thickness0.10.10.3-0.60.6-0.4-0.1-0.1-0.30.3-0.2
Bone: cortical tissue density0.30.30.5-0.50.5-0.40.70.70.6-0.6-0.6
Bone: elastic displacement5.05.77.4-2.72.7-2.52.22.12.2-2.2-2.4
Bone: elastic work0.00.00.1-0.00.00.3-0.2-0.3-0.20.20.3
Bone: endosteal estimation7.716.618.43.8-3.83.9-4.3-4.2-4.24.24.2
Bone: endosteal perimeter6.513.414.53.6-3.63.6-3.8-3.7-3.73.73.7
Bone: final force10.517.318.44.1-4.14.1-4.3-4.2-4.14.14.3
Bone: final moment11.619.220.24.4-4.44.4-4.4-4.4-4.34.34.5
Bone: marrow area7.415.817.93.7-3.73.7-4.2-4.1-4.24.24.1
Bone: maximum diameter2.44.46.31.5-1.51.6-2.4-2.3-2.52.52.1
Bone: maximum force14.925.928.04.8-4.84.9-5.3-5.2-5.15.15.3
Bone: maximum moment16.228.130.15.1-5.15.2-5.5-5.4-5.35.35.5
Bone: minimum diameter8.716.217.73.8-3.83.8-4.2-4.1-4.14.14.1
Bone: periosteal estimation10.621.724.94.2-4.24.3-5.0-4.9-5.05.04.8
Bone: periosteal perimeter9.415.617.43.7-3.73.7-4.2-4.1-4.14.14.0
Bone: post-yield work8.812.013.43.2-3.23.3-3.7-3.6-3.53.53.6
Bone: stiffness18.128.630.25.3-5.35.3-5.4-5.3-5.35.35.5
Bone: tissue strength1.91.82.21.4-1.41.5-1.3-1.3-1.21.21.5
Bone: trabecular number5.78.911.92.4-2.42.5-3.3-3.2-3.43.42.9
Bone: trabecular spacing2.32.93.7-1.41.4-1.41.81.81.9-1.9-1.8
Bone: trabecular thickness0.30.30.90.8-0.80.90.20.20.3-0.30.3
Bone: trabecular tissue density0.20.30.91.0-1.00.80.10.20.2-0.20.2
Breakpoint value in progressive ratio session0.20.20.30.4-0.40.5-0.5-0.3-0.40.40.5
Distance traveled before self-admin1.71.92.9-1.71.7-1.61.21.31.1-1.1-1.0
Distance traveled after self-admin0.50.61.0-1.01.0-1.00.50.80.4-0.4-0.6
Delta time in closed arm before/after self-admin0.20.20.30.5-0.50.4-0.5-0.3-0.50.5-0.1
Delta time in open arm before/after self-admin4.44.25.0-2.12.1-2.22.11.92.1-2.1-1.8
Diff in mean of infusions in LGA sessions1.92.22.81.4-1.41.5-1.4-1.7-1.31.31.6
Extinction: sum of active levers before priming0.50.50.80.7-0.70.5-0.8-0.9-0.70.70.8
Active lever presses in extinction session 60.30.30.40.5-0.50.5-0.6-0.6-0.60.60.4
Delta distance traveled before/after self-admin0.10.10.10.3-0.30.1-0.3-0.0-0.30.30.1
Delta ambulatory time before/after self-admin0.00.00.10.2-0.20.0-0.00.3-0.00.0-0.1
Time in closed arm before self-admin1.21.41.80.9-0.91.2-1.3-1.0-1.21.21.3
Time in closed arm after self-admin0.70.71.31.0-1.01.2-0.9-0.4-0.90.90.3
Time in open arm before self-admin0.50.61.10.5-0.50.4-0.8-1.0-0.90.90.6
Time in open arm after self-admin0.20.20.5-0.50.5-0.70.50.10.6-0.6-0.2
Sum of active levers in priming session hrs 5-60.30.30.6-0.70.7-0.80.20.50.2-0.2-0.8
Time to tail flick, vehicle, before self-admin0.60.60.8-0.60.6-0.70.90.70.9-0.9-0.9
Time to tail flick, vehicle, after self-admin0.70.71.31.1-1.11.0-0.6-0.5-0.50.50.9
Time to tail flick, test, before self-admin0.10.10.4-0.10.1-0.10.40.10.6-0.60.1
Time to tail flick, test, after self-admin0.60.61.11.0-1.00.9-0.6-0.8-0.40.40.8
Delta time to tail flick, vehicle, before/after SA0.60.60.91.0-1.00.9-0.7-0.4-0.60.60.8
Delta time to tail flick, test, before/after SA0.30.30.60.8-0.80.6-0.4-0.2-0.40.40.2
Ambulatory time before self-admin4.04.25.0-2.22.2-2.12.12.02.0-2.0-1.7
Ambulatory time after self-admin2.52.73.6-1.71.7-1.81.51.91.4-1.4-1.7
Total heroin consumption1.61.92.31.3-1.31.4-1.5-1.2-1.41.41.5
Area under the delay curve1.21.32.31.1-1.11.5-1.0-1.1-1.01.01.2
Delay disc. indifference point, 0s delay1.51.62.31.5-1.51.3-1.2-1.1-1.11.11.1
Delay disc. indifference point, 16s delay1.21.22.81.2-1.21.7-0.9-0.7-0.80.81.0
Delay disc. indifference point, 2s delay2.02.23.11.5-1.51.4-1.4-1.8-1.41.41.6
Delay disc. indifference point, 24s delay1.01.01.40.7-0.71.2-1.1-0.9-1.11.11.1
Delay disc. indifference point, 4s delay0.80.81.41.1-1.11.2-0.6-0.8-0.60.60.8
Delay disc. indifference point, 8s delay2.32.33.11.3-1.31.8-1.6-1.6-1.51.51.6
Delay discount exponential model param1.21.22.3-1.11.1-1.51.01.10.9-0.9-1.2
Delay discount hyperbolic model param1.21.32.2-1.11.1-1.51.01.20.9-0.9-1.2
Fecal boli incidents, locomotor time 11.71.92.5-1.21.2-1.01.61.41.6-1.6-1.3
Change in fecal boli incidents, locomotor task1.11.01.60.7-0.70.4-1.2-1.2-1.21.21.1
Time >=10cm from walls, locomotor time 10.10.10.2-0.40.4-0.3-0.3-0.2-0.40.4-0.0
Bouts of movement, locomotor time 10.00.00.00.2-0.20.1-0.1-0.10.1-0.1-0.2
Total resting periods, locomotor time 10.30.30.6-0.50.5-0.50.40.50.6-0.6-0.8
Rest time, locomotor task time 10.60.61.0-0.70.7-0.80.70.80.7-0.7-1.0
Distance moved, locomotor task time 10.00.00.1-0.10.1-0.1-0.2-0.2-0.30.30.0
Vertical activity count, locomotor time 11.31.31.90.9-0.90.8-1.1-1.4-1.21.21.4
Time >=10cm from walls, locomotor time 20.40.40.7-0.30.3-0.40.80.60.8-0.8-0.5
Bouts of movement, locomotor time 22.72.93.31.8-1.81.7-1.8-1.8-1.61.61.6
Total resting periods, locomotor time 23.03.23.61.9-1.91.7-1.9-1.8-1.71.71.7
Rest time, locomotor task time 20.10.10.5-0.40.4-0.7-0.00.0-0.10.1-0.4
Distance moved, locomotor task time 20.00.00.1-0.00.00.10.20.20.2-0.2-0.1
Vertical activity count, locomotor time 20.10.10.20.4-0.40.4-0.1-0.0-0.10.10.3
Weight adjusted by age1.31.52.30.8-0.80.8-1.4-1.4-1.41.41.5
Seeking ratio, delayed vs. immediate footshock0.30.30.50.7-0.70.5-0.6-0.3-0.50.50.6
Locomotion in novel chamber1.31.62.91.7-1.71.5-0.9-0.9-0.80.81.2
Locomotion in novel chamber post-restriction0.20.20.40.6-0.60.6-0.2-0.0-0.20.20.6
Progressive ratio0.40.51.2-1.11.1-1.00.40.30.2-0.2-0.4
Food seeking constrained by brief footshock0.91.12.2-1.31.3-1.50.80.40.8-0.8-0.9
Seeking ratio, punishment vs. effort0.10.10.20.4-0.40.3-0.0-0.20.1-0.10.1
Run reversals in cocaine runway, females0.30.30.70.8-0.80.8-0.1-0.30.1-0.10.2
Run reversals in cocaine runway, males1.51.41.9-0.80.8-1.21.21.41.2-1.2-1.4
Latency to leave start box in cocaine runway0.00.00.00.1-0.10.20.10.10.1-0.1-0.2
Latency to leave start box in cocaine runway, F1.41.62.1-1.11.1-1.01.41.31.3-1.3-1.4
Latency to leave start box in cocaine runway, M2.01.92.11.5-1.51.4-1.4-1.3-1.41.41.2
Cd content in liver0.70.80.9-0.80.8-0.81.01.00.9-0.9-1.0
Co content in liver0.70.91.2-0.70.7-0.71.11.11.1-1.1-0.9
Cu content in liver0.40.40.80.4-0.40.4-0.8-0.9-0.70.70.6
Fe content in liver0.60.71.0-1.01.0-0.90.80.70.8-0.8-0.8
K content in liver0.10.10.1-0.30.3-0.2-0.3-0.2-0.30.30.1
Mg content in liver0.10.10.2-0.50.5-0.40.20.30.1-0.1-0.4
Mn content in liver0.10.20.20.4-0.40.4-0.4-0.3-0.40.40.4
Na content in liver0.10.10.2-0.40.4-0.30.30.30.3-0.3-0.4
Rb content in liver1.31.62.6-1.61.6-1.60.91.00.8-0.8-1.3
Se content in liver1.41.72.4-1.51.5-1.51.11.20.9-0.9-1.5
Sr content in liver0.10.10.20.1-0.10.1-0.3-0.2-0.50.50.1
Zn content in liver2.73.03.4-1.81.8-1.91.71.71.6-1.6-1.8