Hub : Genes

Rab27a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000052499 0.11 0.06 9.8e-10 0.08 0.05 0.07 0.08 2.6e-09 3.7e-06 1.8e-08 6.9e-09
2 BLA gene expression ENSRNOG00000052499 0.44 0.11 0.0e+00 0.33 0.32 0.36 0.38 4.0e-18 6.2e-18 5.4e-20 2.6e-21
3 Brain gene expression ENSRNOG00000052499 0.13 0.06 8.6e-12 0.15 0.13 0.14 0.15 4.5e-14 2.5e-12 1.6e-12 8.0e-14
4 IL gene expression ENSRNOG00000052499 0.3 0.14 1.5e-04 0.21 0.1 0.14 0.15 1.1e-05 2.0e-03 2.9e-04 1.6e-04
5 NAcc gene expression ENSRNOG00000052499 0.12 0.06 2.0e-08 0.11 0.12 0.09 0.11 1.2e-08 4.1e-09 6.9e-07 9.0e-09
6 OFC gene expression ENSRNOG00000052499 0.36 0.15 7.6e-04 0.05 0.04 0.01 0.04 2.1e-02 4.4e-02 1.7e-01 4.3e-02
7 PL gene expression ENSRNOG00000052499 0.3 0.1 0.0e+00 0.32 0.32 0.33 0.34 4.5e-25 1.7e-24 7.6e-26 2.1e-26
8 PL mRNA stability ENSRNOG00000052499 0.07 0.04 2.1e-04 0.06 0.05 0.04 0.04 4.4e-05 1.1e-04 2.8e-04 2.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail6.721.624.74.24.14.94.84.55.04.8-4.9
BMI without tail3.77.710.71.42.82.82.83.32.92.8-2.9
Body weight3.213.615.93.83.13.93.83.24.03.8-3.9
Epididymis fat weight0.00.10.3-0.60.10.0-0.20.50.1-0.20.1
Glucose0.40.60.90.51.00.81.00.40.80.9-0.9
Heart weight0.71.01.51.10.61.01.11.21.01.0-1.0
Left kidney weight2.05.79.33.12.32.42.51.12.52.4-2.5
Right kidney weight1.33.84.51.71.82.12.11.52.12.1-2.1
Tail length0.10.21.1-1.00.2-0.4-0.20.1-0.4-0.20.4
Length with tail0.10.31.01.00.50.40.5-0.10.50.6-0.5
Length without tail1.02.28.22.90.61.31.3-0.11.41.4-1.3
Liver weight, left0.91.52.20.91.51.21.40.71.31.4-1.3
Liver weight, right2.64.35.51.02.32.12.31.92.12.3-2.2
Parametrial fat weight0.40.70.9-0.9-0.7-0.9-0.8-0.9-0.8-0.81.0
Retroperitoneal fat weight0.00.10.2-0.10.30.50.40.40.40.3-0.4
Intraocular pressure0.00.00.00.10.10.0-0.10.1-0.0-0.10.0
Extensor digitorum longus weight7.730.734.34.75.65.95.75.35.85.6-5.8
Soleus weight16.447.751.86.16.97.27.16.47.17.1-7.2
Tibialis anterior weight12.342.446.86.66.86.86.64.96.86.6-6.7
Tibia length0.20.41.30.7-0.9-0.4-0.6-1.1-0.4-0.30.5
Number of licking bursts2.22.53.2-1.8-1.4-1.6-1.7-1.2-1.7-1.71.7
Food consumed during 24 hour testing period0.40.51.61.30.60.60.6-0.70.60.6-0.6
Times rat made contact with spout0.20.20.9-0.2-0.5-0.3-0.4-0.9-0.4-0.30.4
Mean time between licks in bursts1.21.72.1-1.0-1.1-1.3-1.4-1.3-1.4-1.41.4
Mean num. licks in bursts1.41.72.91.71.11.31.40.41.41.4-1.4
Std. dev. time between licks in bursts0.10.10.40.40.40.40.20.70.30.2-0.3
Water consumed over 24 hours0.50.61.1-0.5-0.9-0.7-0.7-1.0-0.7-0.80.7
Indifference point 0 sec0.10.10.2-0.10.30.40.50.30.40.4-0.5
Indifference point AUC0.60.73.0-1.7-0.6-0.4-0.61.1-0.4-0.50.6
Indifference point function ln k0.81.23.61.91.00.71.1-0.60.81.0-1.0
Indifference point function log k0.81.23.61.91.00.71.1-0.60.81.0-1.0
Delay discounting total patch changes 0 sec0.10.20.30.20.40.50.60.30.50.5-0.6
Delay discounting total patch changes 12 sec0.30.31.5-1.2-0.4-0.3-0.50.4-0.3-0.50.4
Delay discounting total patch changes 18 sec0.10.10.3-0.5-0.4-0.2-0.4-0.1-0.1-0.30.3
Delay discounting total patch changes 24 sec0.20.21.0-1.0-0.0-0.0-0.30.80.0-0.20.1
Delay discounting total patch changes 6 sec0.40.63.0-0.90.30.50.51.70.50.5-0.4
Delay discounting time to switch 0 sec0.81.21.6-0.8-0.9-1.1-1.3-1.0-1.1-1.21.2
Delay discounting water rate 0 sec1.72.73.41.81.51.71.71.11.81.8-1.7
Delay discounting water rate 12 sec3.55.26.02.42.32.22.41.42.42.4-2.5
Delay discounting water rate 18 sec0.40.50.70.80.60.70.80.30.70.8-0.8
Delay discounting water rate 24 sec0.00.10.2-0.4-0.2-0.3-0.1-0.2-0.2-0.10.1
Delay discounting water rate 6 sec0.30.41.01.00.60.60.50.40.70.6-0.7
Locomotor activity3.96.29.73.12.42.52.41.42.52.5-2.6
Locomotor testing distance2.33.86.62.61.92.02.00.82.01.9-2.1
Locomotor testing rearing0.81.31.71.11.21.21.10.81.21.1-1.3
Light reinforcement 12.24.15.61.71.52.32.02.42.12.1-2.1
Light reinforcement 21.41.94.8-0.2-1.3-1.3-1.3-2.2-1.3-1.31.2
Reaction time number correct2.33.23.91.72.01.91.81.41.91.8-1.9
Reaction time mean minus median0.40.60.8-0.6-0.7-0.8-0.7-0.7-0.9-0.80.8
Reaction time mean minus median AUC1.01.21.6-1.0-1.0-1.2-1.0-1.2-1.3-1.11.2
Reaction time num false alarms0.10.20.3-0.5-0.1-0.4-0.4-0.5-0.4-0.40.3
Reaction time num false alarms AUC0.10.10.4-0.00.60.20.2-0.20.10.2-0.2
Reaction time trials correct on left2.33.23.91.72.01.91.81.41.91.8-1.9
Reaction time trials on left2.33.24.01.72.01.91.81.41.91.8-1.9
Reaction time mean3.85.26.2-1.8-2.2-2.4-2.4-2.1-2.5-2.42.4
Reaction time mean AUC3.74.95.9-1.9-2.2-2.3-2.3-1.9-2.4-2.32.3
Median of all reaction times4.66.27.2-2.0-2.4-2.6-2.6-2.3-2.7-2.62.6
Reaction time omissions0.00.00.0-0.00.2-0.00.00.2-0.1-0.00.0
Reaction time false alarm rate0.71.11.3-1.1-0.7-1.0-1.0-1.1-1.1-1.01.0
Reaction time premature initiation rate1.01.31.90.61.41.21.20.91.21.3-1.1
Reaction time premature initiations2.73.84.91.52.22.12.11.52.12.1-2.0
Std. dev. reaction times2.02.73.2-1.5-1.5-1.8-1.6-1.5-1.8-1.71.7
Reaction time trials completed2.33.24.01.72.01.91.81.41.91.8-1.9
Reaction time trials AUC2.12.93.61.71.91.81.71.31.81.7-1.8
Social response proportion0.20.20.70.80.20.30.50.00.40.4-0.5
Social responses0.20.20.40.20.30.50.50.50.50.5-0.6
Social time0.20.30.50.70.50.50.6-0.10.60.6-0.6
Conditioned locomotion0.10.20.30.6-0.20.40.30.60.40.3-0.4
Cocaine response after cond. corrected4.04.57.82.82.22.12.10.82.12.1-2.1
Cocaine response after cond. not corrected2.52.85.72.41.71.71.60.21.61.6-1.6
Cocaine response before conditioning1.01.21.7-1.3-1.3-1.1-1.1-0.7-1.0-1.11.0
Saline control response0.10.10.80.40.2-0.1-0.1-0.9-0.1-0.10.1
Condit. Reinf. active minus inactive responses2.53.13.51.91.91.81.81.21.81.8-1.8
Condit. Reinf. active-inactive response ratio1.51.63.41.91.21.21.30.41.21.2-1.2
Condit. Reinf. active responses1.62.22.51.41.41.61.51.31.51.5-1.5
Condit. Reinf. inactive responses0.10.10.7-0.8-0.2-0.1-0.20.5-0.1-0.10.1
Condit. Reinf. lever presses0.60.82.7-0.0-0.9-0.8-0.8-1.6-0.8-0.80.8
Condit. Reinf. lever reinforcers received1.01.41.81.31.11.31.30.91.21.2-1.2
Pavlov. Cond. lever latency0.50.71.30.71.20.80.80.40.80.8-0.8
Pavlov. Cond. magazine entry latency4.55.16.2-1.6-2.4-2.3-2.5-1.9-2.4-2.42.4
Pavlov. Cond. change in total contacts0.71.01.3-0.9-1.2-1.1-1.0-0.6-1.0-1.11.0
Pavlov. Cond. index score1.41.82.5-1.0-1.6-1.4-1.4-0.9-1.4-1.41.4
Pavlov. Cond. latency score1.21.52.0-0.6-1.4-1.2-1.3-1.0-1.3-1.31.3
Pavlov. Cond. lever contacts0.30.41.0-0.6-1.0-0.7-0.6-0.3-0.7-0.70.7
Pavlov. Cond. magazine entry number3.23.94.81.42.12.02.11.52.12.2-2.1
Pavlov. Cond. intertrial magazine entries0.81.01.60.81.31.01.20.41.11.1-1.1
Pavlov. Cond. lever-magazine prob. diff.1.82.33.1-1.1-1.8-1.6-1.6-1.1-1.6-1.61.6
Pavlov. Cond. response bias1.31.82.9-1.3-1.7-1.4-1.4-0.5-1.4-1.41.4
Conditioned reinforcement - actives0.10.10.2-0.10.40.20.30.20.30.3-0.2
Conditioned reinforcement - inactives0.10.10.10.40.40.10.1-0.30.20.1-0.1
Conditioned locomotion0.40.40.7-0.6-0.8-0.7-0.6-0.2-0.7-0.60.7
Intermittent access intake day 1-15 change0.10.10.4-0.30.70.10.1-0.20.10.1-0.0
Intermittent access intake escalation0.10.10.3-0.50.4-0.1-0.2-0.3-0.1-0.10.2
Intermittent access intake escalation 20.10.10.40.20.70.40.30.20.40.3-0.3
Intermitt. access day 1 inactive lever presses0.80.83.8-0.2-0.6-0.8-0.7-1.9-0.7-0.70.7
Intermitt. access day 15 inactive lever presses0.10.10.3-0.3-0.4-0.3-0.4-0.6-0.1-0.30.1
Intermitt. access escalation Index0.70.61.61.30.20.60.71.10.60.6-0.7
Intermittent access day 1 total infusions1.21.43.0-0.4-1.0-1.2-1.1-1.7-1.3-1.21.1
Intermittent access day 15 total infusions0.91.01.8-0.7-0.6-1.1-1.0-1.3-1.1-1.01.0
Intermittent access terminal intake (last 3 days)0.80.81.5-0.6-0.7-1.0-0.8-1.2-1.1-0.90.8
Intermittent access total infusions1.11.23.6-0.3-0.5-1.1-1.0-1.9-1.1-1.01.0
Intermittent access day 1 locomotion2.12.23.6-0.9-1.3-1.7-1.4-1.9-1.6-1.51.5
Intermittent access day 15 total locomotion1.61.73.2-0.1-1.2-1.4-1.3-1.8-1.4-1.31.4
Intermittent access total locomotion0.40.41.50.2-0.3-0.7-0.5-1.2-0.6-0.50.6
Intermittent access standard deviation0.60.71.0-0.6-0.5-0.9-0.9-1.0-0.9-0.90.8
Cocaine induced anxiety0.20.31.0-1.0-0.5-0.2-0.30.7-0.2-0.30.4
Post-drug Anxiety1.51.75.9-2.4-1.1-1.1-1.20.4-1.1-1.11.1
Baseline Anxiety0.50.61.0-1.0-0.5-0.8-0.8-0.3-0.8-0.80.7
Lifetime Intake1.11.22.7-0.5-0.6-1.1-1.1-1.7-1.2-1.11.1
Incentive Sensitization - Responses1.41.42.41.51.01.21.01.21.21.1-1.1
Incentive Sensitization - Breakpoint1.21.21.91.40.91.10.91.21.11.0-1.0
Progressive ratio test 1 active lever presses0.10.10.20.40.50.00.2-0.40.10.2-0.2
Progressive ratio test 1 breakpoint0.10.10.60.00.0-0.4-0.1-0.8-0.3-0.20.2
Progressive ratio test 1 inactive lever presses1.11.23.6-0.6-0.4-1.1-1.1-1.9-0.9-1.01.0
Progressive ratio test 2 active lever presses0.40.40.80.90.70.50.50.50.60.5-0.7
Progressive ratio test 2 breakpoint0.50.51.41.20.80.60.60.40.70.6-0.7
Progressive ratio test 2 inactive lever presses0.91.02.5-0.1-0.8-1.0-1.1-1.6-0.9-1.00.9
Total sessions with >9 infusions0.10.10.50.00.70.00.0-0.70.00.0-0.1
Short access day 1 total inactive lever presses0.70.71.91.41.20.50.5-1.30.50.5-0.4
Short access day 10 total inactive lever presses0.70.82.6-0.1-0.5-0.8-1.0-1.6-0.7-0.90.8
Short access day 1 total infusions0.40.40.80.0-0.3-0.7-0.7-0.9-0.8-0.70.6
Short access day 10 total infusions1.21.32.2-0.6-0.8-1.1-1.2-1.5-1.2-1.21.2
Short access total infusions1.61.84.0-0.9-0.8-1.4-1.3-2.0-1.4-1.31.3
Short access day 1 locomotion0.00.00.10.20.3-0.00.1-0.00.10.1-0.1
Short access day 10 total locomotion0.20.31.40.70.0-0.3-0.1-1.2-0.3-0.10.2
Short access total locomotion1.51.53.7-0.4-0.9-1.3-1.1-1.9-1.3-1.21.2
Compulsive drug intake0.20.20.30.50.40.50.4-0.30.50.5-0.4
One hour access (0.3 mA shock)0.00.00.20.4-0.10.0-0.0-0.40.00.00.1
One hour access (shock baseline)0.50.60.7-0.4-0.8-0.8-0.9-0.7-0.8-0.80.8
Number of responses in last shaping day0.10.10.60.10.2-0.20.0-0.8-0.1-0.00.0
Context. condit. distance diff. score0.20.20.4-0.5-0.6-0.4-0.5-0.6-0.4-0.50.4
Locomotion velocity, session 11.31.42.00.81.41.31.20.71.31.2-1.3
Locomotion distance, session 10.10.10.7-0.8-0.2-0.2-0.2-0.1-0.2-0.20.2
Locomotion velocity, session 20.30.41.1-0.20.40.50.61.10.50.6-0.5
Locomotion distance, session 20.81.23.20.11.01.10.91.81.11.0-1.0
Locomotion velocity, session 30.30.30.7-0.30.70.50.40.90.50.5-0.4
Locomotion distance, session 31.71.82.9-1.7-1.4-1.4-1.4-0.5-1.4-1.41.4
Stereotopy head waving bouts, day 30.40.41.11.00.70.70.5-0.30.70.6-0.6
Stereotopy head waving duration, day 31.01.22.21.51.21.11.0-0.11.11.1-1.1
Locomotion velocity, session 70.70.81.1-0.9-0.9-0.9-1.0-0.4-0.9-0.90.9
Locomotion distance, session 70.60.81.5-1.2-0.8-0.9-1.0-0.1-0.9-0.90.9
Stereotopy head waving bouts, day 71.21.31.60.81.21.31.20.91.31.2-1.2
Stereotopy head waving duration, day 71.31.62.30.81.51.41.41.01.41.3-1.4
Locomotion velocity, session 80.70.81.40.11.20.91.01.00.91.0-0.9
Locomotion distance, session 80.10.21.2-1.1-0.10.0-0.20.70.0-0.1-0.0
Degree of sensitization distance0.00.00.0-0.00.1-0.1-0.20.0-0.1-0.00.1
Degree of sensitization stereotypy1.31.41.70.81.21.31.31.11.31.2-1.3
Condit. Reinf. active minus inactive responses0.40.51.3-1.1-0.9-0.4-0.50.9-0.4-0.50.5
Condit. Reinf. active-inactive response ratio1.11.22.0-0.5-1.4-1.1-1.1-0.9-1.1-1.21.2
Condit. Reinf. active responses0.60.73.6-1.20.10.40.31.90.40.4-0.3
Condit. Reinf. inactive responses1.72.05.6-1.01.41.31.32.41.31.2-1.3
Incentive salience index mean0.30.31.3-0.9-0.7-0.1-0.21.1-0.1-0.10.2
Condit. Reinf. lever presses0.20.21.2-0.7-0.40.20.11.10.20.1-0.1
Time in familiar zone, hab. session 10.10.10.3-0.6-0.50.1-0.10.30.1-0.0-0.1
Time in novel zone, hab. session 10.20.20.60.50.0-0.4-0.4-0.8-0.4-0.40.4
Total zone transitions, hab. session 10.10.10.6-0.8-0.1-0.1-0.30.4-0.1-0.30.1
Total locomotion distance, hab. session 10.10.20.7-0.50.30.30.40.80.30.4-0.3
Locomotion velocity, hab. session 10.20.30.7-0.10.40.50.60.90.50.6-0.5
Time in familiar zone, hab. session 20.10.10.1-0.4-0.0-0.2-0.3-0.3-0.2-0.30.2
Time in novel zone, hab. session 20.10.10.50.7-0.10.00.1-0.40.00.10.0
Total zone transitions, hab. session 20.50.72.9-0.50.30.70.61.70.70.6-0.7
Total locomotion distance, hab. session 20.81.13.5-0.20.50.91.01.90.90.9-1.0
Locomotion velocity, hab. session 20.50.72.6-0.30.30.70.81.60.70.8-0.8
Novel to familiar place preference ratio1.21.21.51.00.91.11.21.11.11.2-1.1
Novelty place preference1.31.41.61.11.01.21.31.11.21.3-1.2
Time in novel zone, NPP test1.41.51.91.41.11.21.30.91.21.3-1.2
Total zone transitions, NPP test0.40.61.7-0.20.40.70.71.30.70.7-0.8
Total locomotion distance, NPP test0.81.12.40.10.81.01.01.51.01.1-1.1
Locomotion velocity, NPP test0.50.72.3-0.40.50.70.71.50.70.7-0.8
Pavlov. Cond. lever latency0.40.42.40.90.2-0.3-0.3-1.5-0.3-0.30.2
Pavlov. Cond. magazine entry latency1.92.45.6-2.4-2.1-1.3-1.40.5-1.3-1.41.3
Pavlov. Cond. change in total contacts0.30.31.0-0.9-0.7-0.2-0.21.0-0.2-0.30.2
Pavlov. Cond. index score1.31.64.8-2.2-1.5-1.0-1.00.9-1.0-1.11.0
Pavlov. Cond. latency score0.91.23.9-2.0-1.2-0.7-0.71.0-0.7-0.80.8
Pavlov. Cond. lever contacts0.30.31.2-0.9-0.6-0.2-0.21.1-0.2-0.20.3
Pavlov. Cond. magazine entry number1.92.44.92.22.11.41.4-0.41.41.5-1.4
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.21.10.60.80.90.60.7-0.7
Pavlov. Cond. lever-magazine prob. diff.1.11.44.2-2.0-1.4-0.9-0.91.0-0.9-0.90.9
Pavlov. Cond. response bias1.01.33.0-1.7-1.5-0.9-0.90.8-0.9-0.90.9
Bone: apparent density0.10.10.2-0.2-0.3-0.4-0.4-0.4-0.3-0.40.5
Bone surface0.20.40.60.70.70.60.50.50.60.6-0.5
Bone volume0.20.30.70.80.60.60.50.30.60.6-0.5
Bone: connectivity density0.81.21.8-1.3-0.8-1.2-1.2-0.6-1.1-1.11.2
Bone: cortical apparent density0.70.91.1-0.9-0.9-0.9-0.9-1.0-0.9-1.00.9
Bone: cortical area0.40.52.91.70.10.20.2-1.10.30.3-0.2
Bone: cortical porosity0.90.91.3-0.7-1.1-1.0-1.1-0.9-1.0-0.91.0
Bone: cortical porosity1.71.92.2-1.2-1.5-1.4-1.5-1.1-1.4-1.31.4
Bone: cortical thickness1.01.74.40.0-1.3-1.2-1.3-2.1-1.2-1.21.2
Bone: cortical thickness0.91.12.9-0.2-0.8-1.0-1.0-1.7-1.0-1.01.0
Bone: cortical tissue density0.70.91.0-0.9-0.9-0.9-0.9-1.0-0.9-1.00.9
Bone: elastic displacement0.00.00.10.00.10.20.20.20.20.3-0.2
Bone: elastic work0.10.10.2-0.1-0.4-0.3-0.3-0.4-0.3-0.20.3
Bone: endosteal estimation2.45.36.02.52.22.42.41.82.42.3-2.4
Bone: endosteal perimeter3.87.810.93.32.62.82.82.12.82.8-2.9
Bone: final force0.71.12.91.70.91.01.00.31.01.1-1.0
Bone: final moment0.40.72.51.60.60.70.7-0.10.70.8-0.7
Bone: marrow area2.55.46.62.62.32.42.41.72.42.4-2.4
Bone: maximum diameter2.24.09.23.01.81.91.90.72.02.0-2.0
Bone: maximum force0.81.32.71.61.01.21.10.51.21.2-1.1
Bone: maximum moment0.50.92.51.60.70.90.80.10.90.9-0.9
Bone: minimum diameter0.10.21.51.2-0.30.10.1-0.50.20.1-0.2
Bone: periosteal estimation1.83.77.12.71.71.91.90.91.91.9-1.9
Bone: periosteal perimeter2.44.06.92.62.02.02.01.02.02.0-2.1
Bone: post-yield work0.40.50.80.20.80.80.80.90.80.7-0.7
Bone: stiffness1.62.53.71.61.91.61.51.01.61.5-1.6
Bone: tissue strength1.51.41.7-0.8-1.2-1.2-1.3-1.3-1.2-1.21.3
Bone: trabecular number0.50.71.0-1.0-0.7-0.9-0.9-0.5-0.9-0.80.9
Bone: trabecular spacing0.00.00.1-0.2-0.3-0.2-0.10.1-0.2-0.20.2
Bone: trabecular thickness0.20.31.21.00.20.1-0.0-1.10.10.10.0
Bone: trabecular tissue density5.67.917.04.13.02.92.50.72.82.7-2.6
Breakpoint value in progressive ratio session0.10.10.4-0.30.10.20.20.60.20.2-0.2
Distance traveled before self-admin0.00.00.10.3-0.1-0.0-0.20.1-0.1-0.10.2
Distance traveled after self-admin1.51.63.92.01.51.41.00.01.11.1-1.1
Delta time in closed arm before/after self-admin0.10.10.50.5-0.2-0.00.1-0.70.00.1-0.1
Delta time in open arm before/after self-admin1.21.11.6-0.8-0.5-0.9-1.3-1.2-1.1-1.21.2
Diff in mean of infusions in LGA sessions0.80.91.8-0.00.81.01.01.41.01.0-0.9
Extinction: sum of active levers before priming0.80.81.3-0.6-0.7-1.1-0.7-1.1-1.0-0.80.8
Active lever presses in extinction session 60.00.00.1-0.40.1-0.1-0.10.2-0.1-0.10.1
Delta distance traveled before/after self-admin2.42.53.91.92.01.81.5-0.11.61.5-1.6
Delta ambulatory time before/after self-admin1.31.43.21.81.41.21.0-0.71.11.0-1.1
Time in closed arm before self-admin0.10.20.7-0.8-0.4-0.4-0.20.3-0.2-0.20.2
Time in closed arm after self-admin0.00.00.1-0.00.00.10.10.00.20.1-0.2
Time in open arm before self-admin1.11.22.31.51.11.21.10.21.01.1-1.2
Time in open arm after self-admin0.20.20.70.50.1-0.2-0.3-0.9-0.3-0.30.3
Sum of active levers in priming session hrs 5-60.10.10.30.50.40.40.30.10.30.3-0.3
Time to tail flick, vehicle, before self-admin0.50.52.2-1.5-0.2-0.20.21.40.10.2-0.1
Time to tail flick, vehicle, after self-admin0.20.20.80.90.40.20.3-0.60.40.3-0.3
Time to tail flick, test, before self-admin0.50.51.0-1.0-1.0-0.7-0.60.4-0.7-0.60.6
Time to tail flick, test, after self-admin1.31.41.6-1.1-0.9-1.3-1.2-1.3-1.2-1.21.1
Delta time to tail flick, vehicle, before/after SA0.70.73.21.2-0.2-0.3-0.4-1.8-0.4-0.40.4
Delta time to tail flick, test, before/after SA0.40.42.10.60.1-0.4-0.3-1.5-0.3-0.30.3
Ambulatory time before self-admin0.40.40.6-0.2-0.6-0.6-0.7-0.3-0.8-0.70.8
Ambulatory time after self-admin0.91.03.31.81.11.00.6-0.70.70.6-0.7
Total heroin consumption1.82.23.60.61.61.61.51.91.41.4-1.4
Area under the delay curve0.00.00.2-0.0-0.30.10.00.40.00.1-0.1
Delay disc. indifference point, 0s delay0.50.61.5-1.2-0.8-0.6-0.80.6-0.7-0.60.6
Delay disc. indifference point, 16s delay0.20.20.6-0.1-0.8-0.5-0.3-0.7-0.5-0.40.4
Delay disc. indifference point, 2s delay0.10.10.2-0.4-0.2-0.3-0.5-0.3-0.3-0.40.3
Delay disc. indifference point, 24s delay0.10.10.2-0.4-0.4-0.4-0.1-0.5-0.4-0.30.2
Delay disc. indifference point, 4s delay0.30.30.6-0.5-0.8-0.5-0.6-0.0-0.5-0.50.6
Delay disc. indifference point, 8s delay0.60.61.60.30.50.80.81.30.80.8-0.8
Delay discount exponential model param0.00.00.2-0.10.2-0.1-0.1-0.4-0.1-0.10.2
Delay discount hyperbolic model param0.00.00.10.00.30.00.1-0.20.10.0-0.0
Fecal boli incidents, locomotor time 10.30.30.7-0.2-0.9-0.5-0.50.3-0.6-0.50.6
Change in fecal boli incidents, locomotor task1.00.92.01.41.00.70.8-0.80.90.9-1.0
Time >=10cm from walls, locomotor time 10.80.81.00.80.71.01.00.90.91.0-0.8
Bouts of movement, locomotor time 10.20.20.50.30.10.50.50.70.40.5-0.3
Total resting periods, locomotor time 10.00.10.10.3-0.10.30.20.40.10.2-0.1
Rest time, locomotor task time 10.50.61.0-0.1-1.0-0.7-0.6-0.9-0.8-0.70.8
Distance moved, locomotor task time 10.10.10.4-0.30.50.20.10.60.30.2-0.3
Vertical activity count, locomotor time 10.10.10.3-0.40.0-0.0-0.10.6-0.1-0.00.1
Time >=10cm from walls, locomotor time 20.00.00.10.3-0.20.20.10.10.10.10.0
Bouts of movement, locomotor time 21.41.52.80.71.01.21.21.71.21.1-1.3
Total resting periods, locomotor time 21.41.52.70.71.01.21.31.61.21.2-1.3
Rest time, locomotor task time 20.70.81.5-0.6-0.9-0.9-0.6-1.2-1.0-0.80.9
Distance moved, locomotor task time 20.30.31.00.10.80.40.31.00.50.5-0.6
Vertical activity count, locomotor time 20.50.60.9-0.6-0.5-0.9-0.9-0.4-0.8-0.90.9
Weight adjusted by age5.35.96.82.62.52.42.52.02.52.5-2.5
Seeking ratio, delayed vs. immediate footshock1.82.03.51.21.31.41.41.91.41.4-1.4
Locomotion in novel chamber1.31.63.8-0.5-1.1-1.2-1.3-1.9-1.1-1.21.3
Locomotion in novel chamber post-restriction0.10.10.4-0.6-0.4-0.3-0.2-0.0-0.4-0.30.2
Progressive ratio0.50.51.3-1.1-1.1-0.5-0.60.3-0.6-0.60.7
Food seeking constrained by brief footshock0.91.11.60.71.31.01.11.11.11.1-1.1
Seeking ratio, punishment vs. effort3.44.26.42.22.51.92.11.32.02.1-2.1
Run reversals in cocaine runway, females0.20.20.60.80.30.4-0.1-0.60.20.0-0.2
Run reversals in cocaine runway, males0.90.92.3-0.31.10.80.91.50.90.8-0.9
Latency to leave start box in cocaine runway1.61.72.11.51.31.31.31.41.21.3-1.3
Latency to leave start box in cocaine runway, F0.50.51.20.40.90.60.71.10.50.6-0.7
Latency to leave start box in cocaine runway, M2.42.34.82.21.01.51.51.31.51.5-1.5
Cd content in liver0.20.21.2-0.5-0.20.0-0.01.10.00.0-0.0
Co content in liver0.10.10.4-0.6-0.7-0.1-0.20.5-0.1-0.10.2
Cu content in liver0.40.50.60.60.60.80.70.80.80.7-0.8
Fe content in liver0.30.41.5-1.2-0.2-0.5-0.5-0.2-0.5-0.50.5
K content in liver1.11.11.40.81.01.11.20.71.11.1-1.2
Mg content in liver2.93.03.71.61.61.81.91.41.81.8-1.9
Mn content in liver0.20.21.10.70.00.10.0-1.00.10.2-0.1
Na content in liver1.41.52.00.71.31.31.31.01.31.4-1.3
Rb content in liver2.73.44.31.42.11.91.91.71.91.8-1.9
Se content in liver0.40.51.1-0.1-0.4-0.7-0.7-1.1-0.7-0.70.7
Sr content in liver0.50.50.7-0.9-0.8-0.7-0.70.1-0.7-0.60.7
Zn content in liver0.30.30.7-0.4-0.8-0.6-0.6-0.5-0.6-0.60.5