Bscl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000052393 0.17 0.08 6.5e-13 0.08 0.1 0.09 0.09 1.9e-09 8.4e-11 5.4e-10 1.8e-10
2 Adipose intron excision ratio chr1:205735190:205735549 0.06 0.03 8.3e-04 0.03 0.02 0.02 0.02 4.2e-04 3.9e-03 5.9e-03 1.5e-03
3 BLA gene expression ENSRNOG00000052393 0.19 0.12 2.7e-07 0.11 0.12 0.11 0.13 2.7e-06 4.7e-07 2.9e-06 1.9e-07
4 Brain gene expression ENSRNOG00000052393 0.24 0.1 6.1e-12 0.1 0.15 0.15 0.16 1.1e-09 1.4e-13 1.1e-13 3.1e-14
5 Brain mRNA stability ENSRNOG00000052393 0.19 0.1 1.5e-11 0.15 0.14 0.14 0.15 9.1e-14 1.5e-12 4.7e-13 1.8e-13
6 Liver alternative TSS ENSRNOT00000098204 0.09 0.05 1.2e-06 0.04 0.04 0.04 0.04 1.5e-05 1.2e-05 1.1e-05 6.9e-05
7 Liver alternative TSS ENSRNOT00000106351 0.08 0.05 5.9e-06 0.04 0.04 0.04 0.03 6.0e-05 7.2e-05 5.6e-05 3.2e-04
8 Liver alternative TSS ENSRNOT00000098204 0.09 0.05 1.0e-06 0.04 0.04 0.04 0.04 1.2e-05 1.2e-05 1.2e-05 6.2e-05
9 Liver alternative TSS ENSRNOT00000106351 0.09 0.05 4.4e-06 0.04 0.04 0.04 0.03 4.8e-05 5.9e-05 4.7e-05 3.1e-04
10 Liver gene expression ENSRNOG00000052393 0.24 0.11 0.0e+00 0.19 0.19 0.2 0.19 2.5e-20 2.2e-20 1.3e-21 1.7e-20
11 Liver isoform ratio ENSRNOT00000098204 0.08 0.05 1.4e-05 0.03 0.04 0.03 0.03 1.0e-04 9.0e-05 1.3e-04 7.5e-04
12 Liver isoform ratio ENSRNOT00000106351 0.09 0.05 2.8e-06 0.04 0.04 0.04 0.03 2.9e-05 3.5e-05 7.4e-05 2.6e-04
13 NAcc gene expression ENSRNOG00000052393 0.29 0.15 5.8e-09 0.02 0.08 0.08 0.07 6.5e-03 2.8e-06 1.0e-06 3.5e-06
14 PL gene expression ENSRNOG00000052393 0.23 0.1 1.3e-09 0.13 0.12 0.12 0.14 4.5e-10 1.7e-09 2.4e-09 1.9e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.72.16.10.4-0.10.81.9-1.60.7-0.90.7-1.02.51.50.12.42.5
BMI without tail0.40.93.20.4-0.81.21.5-0.0-0.40.4-0.50.31.30.00.81.81.5
Body weight0.83.514.72.5-0.31.51.50.90.3-0.40.2-0.53.81.50.32.43.8
Epididymis fat weight0.30.84.6-1.8-0.20.00.8-2.20.1-0.20.1-0.2-1.0-0.20.20.7-0.9
Glucose1.01.56.6-2.60.1-0.60.1-2.30.2-0.20.2-0.2-2.2-0.6-0.1-0.2-2.0
Heart weight1.31.83.2-1.8-1.41.11.6-1.4-1.31.2-1.31.2-1.2-1.61.41.3-0.6
Left kidney weight0.20.51.1-0.30.8-0.6-0.3-0.91.0-1.01.0-1.10.20.8-0.8-0.2-0.1
Right kidney weight0.61.63.2-0.01.5-1.3-0.9-0.61.7-1.81.7-1.80.61.7-1.5-0.5-0.1
Tail length0.51.76.12.1-0.81.30.42.5-0.90.9-0.80.91.6-0.30.80.81.8
Length with tail0.62.38.52.8-0.00.90.32.20.1-0.20.1-0.22.91.00.01.12.9
Length without tail0.51.14.31.70.40.20.10.80.7-0.70.7-0.82.11.3-0.40.52.0
Liver weight, left0.20.30.7-0.6-0.60.40.30.0-0.70.7-0.70.7-0.7-0.80.6-0.1-0.5
Liver weight, right0.30.51.2-0.6-0.80.81.1-0.9-0.60.5-0.60.5-0.2-0.40.81.00.3
Parametrial fat weight0.91.88.4-2.30.6-1.1-0.2-2.90.8-0.80.8-0.9-1.70.2-0.6-0.4-1.8
Retroperitoneal fat weight1.03.514.0-3.7-0.7-0.11.0-3.5-0.60.5-0.60.5-2.9-1.50.70.4-2.7
Intraocular pressure0.20.20.80.30.5-0.5-0.90.30.2-0.20.3-0.2-0.30.1-0.5-0.8-0.6
Extensor digitorum longus weight1.66.225.44.00.21.31.12.20.8-0.90.7-1.05.02.5-0.22.24.9
Soleus weight0.82.58.8-2.8-0.80.00.5-1.7-0.91.0-0.91.0-3.0-1.80.8-0.1-2.6
Tibialis anterior weight2.89.739.05.41.20.5-0.33.71.6-1.71.6-1.76.23.3-1.21.05.3
Tibia length2.36.412.21.82.9-2.3-2.20.73.1-3.13.1-3.12.43.5-2.9-1.50.9
Number of licking bursts0.00.00.0-0.10.1-0.0-0.0-0.10.1-0.10.1-0.1-0.0-0.0-0.10.0-0.0
Food consumed during 24 hour testing period0.20.20.50.00.6-0.6-0.7-0.00.5-0.50.5-0.5-0.20.5-0.6-0.7-0.5
Times rat made contact with spout0.70.81.20.6-0.91.00.61.1-1.01.1-1.01.10.3-0.90.90.70.8
Mean time between licks in bursts2.53.45.70.6-2.22.42.20.6-2.12.0-2.12.00.7-1.62.22.21.8
Mean num. licks in bursts0.30.30.70.2-0.60.50.30.6-0.80.8-0.80.8-0.1-0.70.60.20.1
Std. dev. time between licks in bursts1.92.33.4-0.4-1.81.71.7-0.2-1.81.8-1.81.8-0.6-1.81.81.40.6
Water consumed over 24 hours0.30.41.01.0-0.40.60.21.0-0.50.5-0.50.50.6-0.20.40.40.9
Indifference point 0 sec0.10.21.00.7-0.10.40.30.60.0-0.0-0.0-0.01.00.30.10.50.9
Indifference point AUC3.03.56.11.92.1-1.6-1.91.02.1-2.12.1-2.11.92.5-2.1-1.50.9
Indifference point function ln k6.18.713.5-2.9-3.42.63.2-1.9-3.23.2-3.23.2-2.7-3.73.42.5-0.9
Indifference point function log k6.18.713.5-2.9-3.42.63.2-1.9-3.23.2-3.23.2-2.7-3.73.42.5-0.9
Delay discounting total patch changes 0 sec0.30.51.20.8-0.60.80.70.9-0.60.5-0.60.50.9-0.20.60.81.1
Delay discounting total patch changes 12 sec2.73.611.23.11.3-0.5-1.02.51.4-1.41.4-1.43.32.2-1.3-0.42.4
Delay discounting total patch changes 18 sec0.60.81.41.20.9-0.7-1.00.90.8-0.80.8-0.81.21.0-0.9-0.90.5
Delay discounting total patch changes 24 sec2.02.510.22.50.50.40.21.80.8-0.80.8-0.93.21.6-0.50.92.9
Delay discounting total patch changes 6 sec0.30.52.01.0-0.10.40.40.90.0-0.10.0-0.11.40.50.10.71.4
Delay discounting time to switch 0 sec0.71.02.40.11.1-0.9-0.4-0.81.3-1.41.3-1.40.71.5-1.1-0.00.2
Delay discounting water rate 0 sec0.40.71.5-0.4-0.90.70.40.3-1.11.1-1.01.1-0.9-1.20.90.2-0.3
Delay discounting water rate 12 sec3.14.78.8-1.5-2.52.12.0-0.4-2.62.6-2.62.6-1.9-3.02.51.4-0.6
Delay discounting water rate 18 sec4.15.47.9-1.4-2.82.52.7-0.8-2.72.7-2.72.6-1.3-2.72.82.40.2
Delay discounting water rate 24 sec1.52.14.1-1.2-1.61.21.2-0.4-1.71.7-1.71.7-1.5-2.01.60.8-0.6
Delay discounting water rate 6 sec2.53.67.0-1.3-2.21.81.8-0.2-2.32.3-2.32.3-1.5-2.62.21.3-0.4
Locomotor activity2.23.57.0-0.8-2.21.91.70.2-2.42.4-2.42.4-1.2-2.62.21.2-0.2
Locomotor testing distance3.65.910.2-1.2-2.92.52.4-0.2-3.03.0-3.03.0-1.4-3.22.92.0-0.1
Locomotor testing rearing1.82.84.9-1.2-1.91.51.5-0.5-2.02.0-2.02.0-1.4-2.21.91.2-0.5
Light reinforcement 10.00.10.20.1-0.10.0-0.30.2-0.30.3-0.30.3-0.3-0.40.1-0.4-0.3
Light reinforcement 22.83.75.4-0.52.3-2.3-1.9-1.32.3-2.32.3-2.3-0.22.0-2.3-1.8-1.3
Reaction time number correct0.50.71.60.9-0.81.10.71.1-0.80.8-0.80.80.7-0.40.80.91.3
Reaction time mean minus median3.24.16.71.32.4-2.3-2.60.72.2-2.22.2-2.21.02.3-2.4-2.4-0.2
Reaction time mean minus median AUC1.31.73.91.31.5-1.4-2.01.21.2-1.11.2-1.10.61.2-1.5-1.9-0.2
Reaction time num false alarms2.12.95.3-0.2-2.11.91.50.4-2.22.2-2.22.2-0.5-2.32.11.10.3
Reaction time num false alarms AUC2.33.25.20.4-2.12.11.51.1-2.22.3-2.22.30.1-2.22.11.20.8
Reaction time trials correct on left0.50.71.60.9-0.81.10.71.1-0.80.8-0.80.80.7-0.40.80.91.3
Reaction time trials on left0.50.81.61.0-0.81.10.61.2-0.80.8-0.80.80.7-0.40.80.91.3
Reaction time mean1.31.73.30.51.6-1.7-1.80.21.4-1.31.4-1.30.11.4-1.6-1.8-0.6
Reaction time mean AUC1.31.73.20.31.5-1.7-1.80.11.3-1.31.4-1.3-0.21.3-1.5-1.8-0.8
Median of all reaction times0.60.81.20.41.1-1.1-1.10.01.0-1.01.0-0.90.11.1-1.1-1.1-0.3
Reaction time omissions0.30.41.91.10.3-0.3-0.91.4-0.00.00.00.10.50.1-0.3-1.00.2
Reaction time false alarm rate1.11.52.9-0.4-1.51.31.10.1-1.61.6-1.61.6-0.4-1.71.50.7-0.0
Reaction time premature initiation rate2.02.77.41.6-1.52.12.10.8-1.21.1-1.21.02.0-0.21.52.42.7
Reaction time premature initiations2.83.910.62.3-1.72.52.01.8-1.51.4-1.51.42.4-0.41.72.53.3
Std. dev. reaction times1.72.35.70.81.8-1.9-2.30.81.4-1.41.4-1.30.11.3-1.8-2.4-0.8
Reaction time trials completed0.50.81.61.0-0.81.10.61.2-0.80.8-0.80.80.7-0.40.80.91.3
Reaction time trials AUC0.50.81.40.8-0.91.10.81.0-0.80.9-0.80.80.6-0.50.91.01.2
Social response proportion0.10.10.30.2-0.40.50.4-0.1-0.30.3-0.30.30.3-0.20.40.40.4
Social responses0.30.41.20.8-0.50.60.01.1-0.70.7-0.70.70.2-0.60.50.00.4
Social time0.40.50.90.4-0.70.70.21.0-0.90.9-0.80.90.0-0.90.70.10.1
Conditioned locomotion0.20.20.80.7-0.10.30.20.8-0.00.0-0.00.00.90.20.10.40.9
Cocaine response after cond. corrected1.92.13.3-1.2-1.71.41.7-0.7-1.71.6-1.71.6-0.9-1.81.71.3-0.3
Cocaine response after cond. not corrected1.21.31.7-1.0-1.31.01.3-1.1-1.31.2-1.31.2-0.9-1.31.31.0-0.3
Cocaine response before conditioning1.01.22.60.91.3-1.0-1.2-0.11.2-1.21.2-1.20.51.6-1.3-1.00.1
Saline control response0.91.23.71.6-0.71.20.81.1-0.60.6-0.60.51.80.10.71.11.9
Condit. Reinf. active minus inactive responses1.01.22.0-0.21.3-1.4-1.4-0.11.2-1.11.2-1.1-0.40.9-1.3-1.4-1.1
Condit. Reinf. active-inactive response ratio3.13.25.2-0.92.1-2.3-1.8-1.02.1-2.12.1-2.1-0.51.6-2.1-1.7-1.7
Condit. Reinf. active responses0.10.10.30.20.5-0.4-0.50.20.4-0.40.4-0.40.00.4-0.5-0.5-0.2
Condit. Reinf. inactive responses1.21.52.40.5-1.41.61.10.6-1.51.5-1.51.50.1-1.21.41.00.9
Condit. Reinf. lever presses0.70.92.11.01.0-0.6-0.70.31.1-1.11.1-1.11.11.4-1.0-0.40.7
Condit. Reinf. lever reinforcers received0.30.40.60.60.7-0.6-0.80.50.6-0.60.6-0.60.40.7-0.7-0.70.0
Pavlov. Cond. lever latency0.20.31.0-0.4-0.50.20.10.4-0.70.7-0.70.7-0.7-1.00.5-0.1-0.6
Pavlov. Cond. magazine entry latency1.51.85.82.40.8-0.1-0.61.30.9-0.90.9-0.92.41.8-0.8-0.12.0
Pavlov. Cond. change in total contacts1.82.65.91.41.8-1.3-1.40.11.9-1.91.9-1.91.52.4-1.8-1.10.7
Pavlov. Cond. index score1.62.15.21.71.4-0.8-0.90.41.5-1.61.5-1.61.92.3-1.4-0.51.3
Pavlov. Cond. latency score1.51.94.91.51.4-0.8-0.80.21.5-1.61.5-1.61.82.2-1.4-0.51.2
Pavlov. Cond. lever contacts0.30.41.00.80.7-0.4-0.60.10.7-0.70.7-0.70.71.0-0.7-0.50.5
Pavlov. Cond. magazine entry number2.83.510.1-3.0-1.40.40.9-1.6-1.51.5-1.51.5-3.2-2.61.40.2-2.5
Pavlov. Cond. intertrial magazine entries0.50.62.5-1.20.3-0.7-0.6-0.50.1-0.10.1-0.0-1.4-0.6-0.3-1.0-1.6
Pavlov. Cond. lever-magazine prob. diff.1.62.05.11.91.3-0.7-0.90.51.4-1.51.4-1.52.02.3-1.3-0.41.5
Pavlov. Cond. response bias0.81.02.41.50.9-0.4-0.60.50.9-0.90.9-0.91.61.5-0.9-0.41.2
Conditioned reinforcement - actives2.12.03.5-1.01.5-1.9-1.7-1.21.3-1.21.3-1.2-1.30.6-1.5-1.9-1.8
Conditioned reinforcement - inactives1.51.72.9-1.21.4-1.6-1.1-1.71.4-1.41.4-1.4-1.01.0-1.4-1.0-1.2
Conditioned locomotion0.91.14.3-2.10.4-0.9-0.2-2.10.5-0.50.5-0.5-1.5-0.0-0.4-0.5-1.6
Intermittent access intake day 1-15 change2.22.25.7-0.21.7-1.9-2.2-0.01.4-1.31.4-1.2-0.80.8-1.7-2.4-1.5
Intermittent access intake escalation1.71.74.3-0.01.5-1.7-1.90.11.2-1.21.2-1.1-0.60.8-1.5-2.1-1.2
Intermittent access intake escalation 22.02.04.00.71.7-1.7-1.90.51.5-1.51.5-1.40.31.3-1.7-2.0-0.4
Intermitt. access day 1 inactive lever presses0.80.82.9-1.60.4-0.8-0.4-1.70.4-0.30.4-0.3-1.5-0.1-0.4-0.6-1.5
Intermitt. access day 15 inactive lever presses1.31.42.7-0.51.3-1.1-0.6-1.61.5-1.51.5-1.60.11.5-1.3-0.3-0.2
Intermitt. access escalation Index1.71.52.2-0.9-1.51.31.5-1.0-1.31.3-1.31.3-0.8-1.31.51.50.0
Intermittent access day 1 total infusions1.31.510.4-2.5-0.1-0.21.0-3.20.4-0.40.3-0.5-1.00.10.10.9-0.9
Intermittent access day 15 total infusions2.32.67.3-2.31.3-1.7-1.0-2.71.3-1.31.3-1.3-1.80.6-1.3-1.3-2.2
Intermittent access terminal intake (last 3 days)2.42.75.8-1.51.7-1.8-1.0-2.41.9-1.91.9-1.9-0.51.5-1.7-1.0-1.1
Intermittent access total infusions1.51.66.0-1.81.0-1.3-0.4-2.51.2-1.31.2-1.3-0.90.9-1.0-0.4-1.2
Intermittent access day 1 locomotion1.31.46.8-2.0-0.80.61.7-2.6-0.30.2-0.30.1-0.5-0.20.81.8-0.1
Intermittent access day 15 total locomotion0.91.02.8-1.20.9-1.0-0.3-1.71.1-1.21.1-1.2-0.21.0-0.9-0.3-0.6
Intermittent access total locomotion1.92.18.6-1.81.2-1.20.1-2.91.6-1.71.6-1.8-0.21.5-1.20.2-0.5
Intermittent access standard deviation1.01.13.1-0.51.1-1.4-1.5-0.00.8-0.80.8-0.7-0.90.3-1.1-1.8-1.4
Cocaine induced anxiety0.60.71.10.61.0-0.8-0.80.11.0-1.01.0-1.00.81.1-1.0-0.80.3
Post-drug Anxiety1.51.72.41.01.5-1.2-1.30.51.5-1.51.5-1.51.11.6-1.5-1.10.5
Baseline Anxiety0.40.41.41.2-0.30.60.31.1-0.20.2-0.20.21.00.10.30.61.2
Lifetime Intake0.80.95.7-1.90.3-0.50.3-2.40.5-0.50.5-0.6-1.00.2-0.30.2-1.1
Incentive Sensitization - Responses0.90.91.6-0.21.1-1.0-0.6-0.81.2-1.31.2-1.30.31.2-1.1-0.4-0.0
Incentive Sensitization - Breakpoint1.01.01.8-0.31.2-1.1-0.6-1.01.3-1.31.3-1.30.21.3-1.2-0.4-0.1
Progressive ratio test 1 active lever presses0.70.72.5-1.50.3-0.8-0.4-1.10.3-0.30.3-0.2-1.4-0.3-0.3-0.6-1.6
Progressive ratio test 1 breakpoint0.80.82.8-1.50.4-0.9-0.5-1.10.3-0.30.3-0.3-1.5-0.3-0.4-0.7-1.7
Progressive ratio test 1 inactive lever presses0.40.41.3-0.4-0.70.71.0-0.5-0.50.5-0.50.50.0-0.40.71.10.3
Progressive ratio test 2 active lever presses1.41.53.3-1.71.1-1.4-0.8-1.81.1-1.11.1-1.1-1.20.6-1.1-0.9-1.6
Progressive ratio test 2 breakpoint1.61.84.2-1.81.1-1.6-1.1-1.71.0-1.01.0-1.0-1.60.3-1.1-1.3-2.0
Progressive ratio test 2 inactive lever presses1.31.53.8-1.51.2-1.3-0.6-2.01.3-1.31.3-1.3-0.70.9-1.2-0.6-1.2
Total sessions with >9 infusions1.21.35.0-2.2-0.80.31.1-2.2-0.60.5-0.60.5-1.6-0.90.80.8-1.1
Short access day 1 total inactive lever presses0.80.93.2-1.8-0.70.31.0-1.7-0.50.4-0.50.4-1.2-0.70.70.9-0.8
Short access day 10 total inactive lever presses2.02.23.8-1.8-1.61.01.2-1.2-1.61.6-1.61.6-1.8-1.91.60.7-1.3
Short access day 1 total infusions0.91.03.6-1.7-0.80.51.0-1.9-0.60.5-0.60.5-1.1-0.80.80.9-0.9
Short access day 10 total infusions1.01.18.0-1.9-0.30.11.1-2.80.1-0.20.1-0.3-0.70.10.31.2-0.4
Short access total infusions1.01.14.8-1.8-0.80.61.4-2.2-0.50.5-0.50.4-0.8-0.60.81.3-0.5
Short access day 1 locomotion0.70.72.7-1.1-0.70.71.4-1.6-0.30.2-0.30.2-0.1-0.10.71.60.4
Short access day 10 total locomotion0.40.42.9-1.0-0.20.20.8-1.70.1-0.20.1-0.3-0.10.20.20.90.2
Short access total locomotion0.70.72.7-1.0-0.60.61.4-1.6-0.10.0-0.2-0.00.20.10.61.60.6
Compulsive drug intake4.04.06.21.4-2.22.41.72.5-2.22.2-2.22.20.7-1.72.22.01.6
One hour access (0.3 mA shock)1.72.06.4-2.50.7-1.2-0.5-2.50.7-0.70.7-0.7-2.1-0.1-0.7-0.8-2.3
One hour access (shock baseline)4.45.18.6-2.52.2-2.7-2.1-2.82.0-2.02.0-2.0-2.11.0-2.2-2.5-2.9
Number of responses in last shaping day0.80.81.4-0.2-1.21.11.00.1-1.11.1-1.11.10.0-1.01.20.90.2
Context. condit. distance diff. score0.80.91.8-1.2-1.10.81.3-0.8-0.90.9-0.90.9-0.7-1.01.11.1-0.3
Locomotion velocity, session 11.41.52.5-0.4-1.51.41.6-0.1-1.41.4-1.41.3-0.2-1.21.51.50.6
Locomotion distance, session 10.81.13.2-0.0-1.21.31.6-0.2-0.90.9-0.90.80.6-0.61.21.81.0
Locomotion velocity, session 20.60.73.61.30.10.40.30.60.3-0.30.3-0.41.90.8-0.10.71.6
Locomotion distance, session 20.40.61.00.2-0.91.00.90.4-0.80.8-0.80.80.5-0.70.91.00.7
Locomotion velocity, session 30.60.73.1-0.7-0.70.91.5-1.0-0.30.3-0.30.20.3-0.20.71.80.7
Locomotion distance, session 30.40.40.8-0.1-0.80.90.8-0.1-0.70.7-0.70.70.1-0.60.80.90.5
Stereotopy head waving bouts, day 30.40.52.2-1.5-0.30.11.1-1.30.1-0.10.0-0.2-0.3-0.20.31.1-0.3
Stereotopy head waving duration, day 30.40.41.4-1.2-0.60.41.1-0.8-0.40.3-0.40.3-0.3-0.60.61.0-0.3
Locomotion velocity, session 70.10.10.4-0.70.1-0.20.2-0.40.3-0.30.3-0.3-0.10.1-0.10.3-0.3
Locomotion distance, session 70.70.91.9-1.0-1.11.01.4-0.8-0.90.9-0.90.9-0.4-1.11.11.30.1
Stereotopy head waving bouts, day 70.80.91.50.01.1-1.1-0.8-0.01.2-1.21.2-1.20.41.2-1.1-0.5-0.2
Stereotopy head waving duration, day 70.70.92.41.20.8-0.3-0.30.60.9-0.90.9-1.01.61.4-0.80.21.2
Locomotion velocity, session 81.21.42.2-0.2-1.41.31.20.6-1.51.5-1.51.5-0.2-1.51.41.00.2
Locomotion distance, session 80.40.51.7-1.3-0.60.41.1-1.1-0.40.4-0.40.3-0.5-0.60.61.0-0.4
Degree of sensitization distance0.40.42.4-1.2-0.20.10.9-1.50.1-0.10.1-0.2-0.3-0.00.20.8-0.1
Degree of sensitization stereotypy1.31.42.90.91.3-1.0-1.00.51.4-1.41.4-1.41.11.7-1.3-0.60.4
Condit. Reinf. active minus inactive responses0.30.41.31.00.3-0.0-0.10.70.4-0.40.4-0.41.00.8-0.30.21.1
Condit. Reinf. active-inactive response ratio0.20.21.10.9-0.10.30.01.1-0.20.2-0.20.20.60.10.10.10.9
Condit. Reinf. active responses0.81.02.40.71.1-0.8-0.50.01.2-1.31.2-1.31.01.6-1.1-0.20.8
Condit. Reinf. inactive responses1.21.42.4-0.51.3-1.3-0.8-1.41.5-1.51.5-1.6-0.01.4-1.3-0.6-0.5
Incentive salience index mean0.30.41.60.80.20.10.30.10.4-0.50.4-0.51.10.9-0.20.71.3
Condit. Reinf. lever presses0.20.30.80.30.10.20.5-0.60.4-0.50.4-0.50.80.9-0.10.80.9
Time in familiar zone, hab. session 10.10.10.6-0.0-0.20.20.4-0.7-0.10.0-0.10.00.10.20.20.50.5
Time in novel zone, hab. session 10.80.81.8-0.9-0.90.50.4-0.0-1.01.0-1.01.0-1.3-1.40.90.2-0.9
Total zone transitions, hab. session 10.10.10.40.6-0.10.20.10.7-0.10.1-0.10.00.70.10.10.10.6
Total locomotion distance, hab. session 10.20.30.7-0.70.5-0.6-0.1-0.90.7-0.70.6-0.7-0.10.5-0.5-0.1-0.4
Locomotion velocity, hab. session 10.20.30.6-0.00.6-0.5-0.2-0.20.7-0.70.7-0.80.50.7-0.6-0.20.1
Time in familiar zone, hab. session 20.90.91.80.0-1.11.00.5-0.0-1.31.3-1.31.4-0.8-1.21.10.40.1
Time in novel zone, hab. session 20.20.20.70.10.3-0.10.3-0.00.5-0.60.5-0.60.80.7-0.30.40.4
Total zone transitions, hab. session 20.70.92.60.7-0.81.21.30.1-0.60.6-0.60.51.20.00.81.61.6
Total locomotion distance, hab. session 20.20.31.0-0.3-0.50.50.9-0.8-0.20.2-0.30.20.2-0.10.51.00.5
Locomotion velocity, hab. session 20.10.21.0-0.5-0.10.20.7-1.00.1-0.10.1-0.20.10.10.10.70.2
Novel to familiar place preference ratio1.31.33.21.21.1-0.7-0.70.61.3-1.31.3-1.31.81.6-1.1-0.31.0
Novelty place preference1.01.12.00.91.1-0.7-0.70.31.2-1.21.2-1.21.41.4-1.1-0.40.7
Time in novel zone, NPP test0.80.82.10.90.9-0.5-0.50.41.0-1.11.0-1.11.41.2-0.9-0.20.8
Total zone transitions, NPP test0.50.71.91.0-0.60.90.80.8-0.50.5-0.50.41.3-0.00.61.01.4
Total locomotion distance, NPP test0.30.40.8-0.2-0.70.70.9-0.1-0.60.6-0.60.50.3-0.50.70.90.4
Locomotion velocity, NPP test0.10.20.3-0.1-0.50.50.60.1-0.40.4-0.40.40.2-0.40.50.50.2
Pavlov. Cond. lever latency0.50.61.7-0.5-0.60.2-0.20.7-0.80.9-0.80.9-1.1-1.30.6-0.4-1.0
Pavlov. Cond. magazine entry latency1.21.63.90.71.4-1.0-0.7-0.61.6-1.61.6-1.61.12.0-1.4-0.30.7
Pavlov. Cond. change in total contacts2.12.24.10.31.8-1.6-1.3-0.81.9-1.91.9-1.90.72.0-1.8-1.1-0.1
Pavlov. Cond. index score0.81.02.30.71.1-0.9-0.8-0.21.2-1.21.2-1.20.91.5-1.1-0.50.5
Pavlov. Cond. latency score0.40.51.40.50.7-0.5-0.3-0.50.9-0.90.9-0.90.71.2-0.7-0.10.5
Pavlov. Cond. lever contacts0.20.20.60.10.4-0.20.1-0.70.5-0.50.5-0.60.40.8-0.40.20.4
Pavlov. Cond. magazine entry number1.41.83.4-1.1-1.51.31.4-0.3-1.51.5-1.51.5-1.0-1.81.51.1-0.4
Pavlov. Cond. intertrial magazine entries0.70.91.80.71.1-1.0-1.30.80.9-0.90.9-0.90.40.9-1.1-1.3-0.4
Pavlov. Cond. lever-magazine prob. diff.1.11.33.00.81.3-1.0-0.9-0.21.4-1.41.4-1.41.01.7-1.3-0.60.5
Pavlov. Cond. response bias1.11.33.10.81.3-1.0-1.0-0.31.4-1.41.4-1.41.01.7-1.3-0.60.5
Bone: apparent density0.20.30.7-0.00.3-0.20.3-0.70.6-0.60.6-0.70.40.8-0.30.60.6
Bone surface1.32.35.61.01.5-1.0-0.6-0.21.9-1.91.8-1.91.72.4-1.5-0.01.3
Bone volume1.11.94.40.41.5-1.2-0.7-0.61.8-1.81.8-1.91.02.1-1.5-0.30.6
Bone: connectivity density0.40.72.50.80.20.20.6-0.20.6-0.60.6-0.71.41.2-0.21.11.6
Bone: cortical apparent density0.30.42.21.20.00.1-0.31.5-0.10.1-0.10.10.70.2-0.0-0.20.8
Bone: cortical area0.71.02.30.81.1-0.6-0.60.31.2-1.21.2-1.31.21.5-1.1-0.30.7
Bone: cortical porosity0.20.20.70.30.4-0.5-0.70.80.2-0.10.2-0.10.1-0.0-0.4-0.8-0.3
Bone: cortical porosity0.20.21.40.60.1-0.1-0.51.2-0.10.1-0.10.20.4-0.2-0.1-0.50.1
Bone: cortical thickness1.22.07.12.6-0.41.10.22.7-0.50.5-0.50.52.20.30.40.62.3
Bone: cortical thickness0.81.01.61.0-1.01.20.61.3-1.11.1-1.11.10.6-0.71.00.81.1
Bone: cortical tissue density0.30.52.61.40.00.2-0.41.6-0.10.1-0.10.20.80.2-0.0-0.20.9
Bone: elastic displacement0.91.02.2-0.2-1.10.90.50.5-1.31.4-1.31.4-0.9-1.51.10.4-0.3
Bone: elastic work1.11.52.21.0-1.31.51.11.2-1.31.3-1.31.30.8-0.81.31.31.4
Bone: endosteal estimation1.12.510.9-2.80.8-1.20.2-3.31.2-1.31.2-1.4-1.50.7-0.80.0-1.8
Bone: endosteal perimeter2.44.912.1-3.01.9-2.4-0.9-3.52.3-2.32.3-2.4-1.71.5-1.9-1.2-2.5
Bone: final force0.61.03.01.10.7-0.10.10.31.0-1.01.0-1.11.71.6-0.70.61.6
Bone: final moment0.61.03.01.10.7-0.20.10.31.0-1.01.0-1.11.71.6-0.70.61.6
Bone: marrow area1.22.511.1-2.90.8-1.20.2-3.31.2-1.21.1-1.3-1.70.6-0.80.0-1.9
Bone: maximum diameter1.01.93.5-0.11.6-1.4-0.9-0.71.8-1.91.8-1.90.71.8-1.6-0.9-0.2
Bone: maximum force1.32.35.90.81.3-0.70.0-0.61.8-1.91.8-1.92.12.4-1.30.61.6
Bone: maximum moment1.12.05.20.81.2-0.60.1-0.51.7-1.71.6-1.82.02.3-1.20.61.6
Bone: minimum diameter1.12.17.6-2.11.1-1.3-0.1-2.81.5-1.51.5-1.6-1.01.1-1.1-0.1-1.3
Bone: periosteal estimation1.02.13.8-1.21.5-1.4-0.5-1.91.8-1.91.8-2.0-0.11.7-1.5-0.4-0.6
Bone: periosteal perimeter1.22.03.5-0.61.6-1.5-1.0-1.21.8-1.81.8-1.90.11.6-1.6-0.9-0.6
Bone: post-yield work2.93.97.6-1.72.0-2.1-0.7-2.82.4-2.52.4-2.6-0.32.2-2.0-0.7-1.1
Bone: stiffness1.21.94.20.61.6-1.2-0.9-0.31.8-1.81.8-1.81.22.1-1.6-0.60.5
Bone: tissue strength0.10.10.4-0.3-0.30.20.2-0.4-0.30.3-0.30.3-0.7-0.40.30.1-0.4
Bone: trabecular number0.40.51.40.30.6-0.30.2-0.50.9-0.90.9-1.00.81.2-0.60.60.9
Bone: trabecular spacing0.81.12.20.0-1.21.10.50.4-1.41.5-1.41.5-0.6-1.41.20.2-0.2
Bone: trabecular thickness0.81.01.7-0.51.1-1.3-1.0-0.71.1-1.11.1-1.1-0.60.9-1.1-0.9-0.8
Bone: trabecular tissue density1.11.65.8-1.8-0.4-0.3-0.3-0.7-0.80.8-0.80.9-2.4-1.60.4-1.1-2.4
Breakpoint value in progressive ratio session1.61.84.32.11.2-0.7-1.32.01.1-1.01.1-1.01.81.4-1.2-1.11.1
Distance traveled before self-admin1.71.83.61.61.3-0.8-1.00.91.4-1.41.4-1.41.71.9-1.3-0.61.2
Distance traveled after self-admin0.60.71.00.90.9-0.7-1.00.90.8-0.80.8-0.80.51.0-0.9-0.70.4
Delta time in closed arm before/after self-admin4.14.06.90.4-2.32.62.60.8-2.12.0-2.12.00.9-1.62.32.61.9
Delta time in open arm before/after self-admin2.82.64.81.41.9-1.5-1.60.71.9-1.91.9-1.91.42.2-1.9-1.10.7
Diff in mean of infusions in LGA sessions0.80.94.12.00.40.0-0.61.90.2-0.20.2-0.21.50.6-0.4-0.31.4
Extinction: sum of active levers before priming1.51.54.02.00.9-0.3-0.51.30.9-1.00.9-1.02.01.6-0.90.01.9
Active lever presses in extinction session 62.62.54.62.11.6-1.2-1.51.61.6-1.51.6-1.51.72.1-1.6-1.11.2
Delta distance traveled before/after self-admin0.60.71.4-0.6-0.90.60.6-0.2-1.01.0-1.01.0-1.1-1.20.90.5-0.4
Delta ambulatory time before/after self-admin1.11.22.6-0.8-1.20.90.7-0.2-1.31.3-1.31.4-1.2-1.61.20.4-0.6
Time in closed arm before self-admin1.01.21.8-0.01.3-1.3-1.2-0.51.3-1.31.3-1.3-0.11.2-1.3-1.0-0.6
Time in closed arm after self-admin0.80.91.4-1.0-1.00.91.0-0.7-1.01.0-1.01.0-0.9-1.21.00.8-0.5
Time in open arm before self-admin4.85.18.9-1.0-2.82.42.2-0.2-2.82.8-2.82.8-1.2-3.02.81.8-0.1
Time in open arm after self-admin0.30.31.80.7-0.30.3-0.11.3-0.50.5-0.50.50.3-0.40.3-0.20.3
Sum of active levers in priming session hrs 5-65.15.07.72.02.6-2.3-2.81.52.4-2.42.4-2.31.42.6-2.6-2.50.2
Time to tail flick, vehicle, before self-admin0.60.61.4-0.20.6-0.40.1-1.20.9-0.90.9-1.00.71.1-0.60.40.4
Time to tail flick, vehicle, after self-admin0.70.81.9-0.0-1.01.21.3-0.2-0.80.7-0.80.70.5-0.51.01.40.9
Time to tail flick, test, before self-admin1.11.13.4-0.7-1.21.31.8-0.5-0.80.7-0.80.60.4-0.61.21.80.8
Time to tail flick, test, after self-admin0.00.00.1-0.20.0-0.0-0.20.2-0.00.0-0.00.1-0.2-0.2-0.0-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.60.60.80.1-0.90.90.80.5-0.90.9-0.90.9-0.0-0.80.90.60.4
Delta time to tail flick, test, before/after SA1.11.02.91.01.1-1.1-1.71.20.7-0.60.7-0.60.00.6-1.1-1.7-0.5
Ambulatory time before self-admin2.72.85.51.71.9-1.4-1.60.81.9-1.91.9-1.91.42.4-1.9-0.90.9
Ambulatory time after self-admin1.01.12.00.51.3-1.1-1.0-0.11.3-1.31.3-1.30.51.4-1.3-0.80.1
Total heroin consumption1.72.18.02.80.7-0.0-0.92.70.5-0.50.5-0.52.41.1-0.7-0.61.9
Area under the delay curve0.40.41.1-0.5-0.70.71.0-0.8-0.50.5-0.50.5-0.0-0.50.71.00.3
Delay disc. indifference point, 0s delay1.51.63.0-1.4-1.41.21.7-1.7-1.11.1-1.11.0-0.6-1.21.41.7-0.0
Delay disc. indifference point, 16s delay0.20.20.4-0.20.4-0.30.1-0.70.5-0.60.5-0.60.20.6-0.40.30.2
Delay disc. indifference point, 2s delay0.30.42.9-1.0-0.1-0.00.4-1.70.1-0.10.1-0.1-0.5-0.10.10.5-0.4
Delay disc. indifference point, 24s delay0.80.81.30.0-1.11.11.10.3-1.01.0-1.00.90.3-0.81.11.00.6
Delay disc. indifference point, 4s delay1.61.63.8-0.2-1.51.61.8-0.5-1.31.2-1.31.20.3-1.11.51.91.0
Delay disc. indifference point, 8s delay1.11.12.2-0.8-1.31.11.2-0.2-1.31.2-1.31.2-0.6-1.51.30.9-0.2
Delay discount exponential model param0.40.41.00.50.7-0.7-1.00.70.5-0.50.5-0.5-0.00.5-0.7-1.0-0.3
Delay discount hyperbolic model param0.40.41.10.50.7-0.7-1.00.90.5-0.50.5-0.5-0.00.5-0.7-1.1-0.3
Fecal boli incidents, locomotor time 12.12.33.6-0.21.8-1.9-1.8-0.61.7-1.71.7-1.7-0.21.5-1.8-1.8-1.0
Change in fecal boli incidents, locomotor task3.12.94.6-1.3-2.01.71.9-1.2-1.91.9-1.91.9-1.0-2.12.01.8-0.1
Time >=10cm from walls, locomotor time 12.52.53.7-1.81.5-1.9-1.2-1.91.6-1.61.6-1.6-1.51.0-1.5-1.4-1.9
Bouts of movement, locomotor time 11.11.25.21.70.9-0.8-1.72.30.5-0.40.5-0.40.60.5-0.9-1.6-0.0
Total resting periods, locomotor time 11.11.23.41.51.1-1.0-1.71.80.8-0.70.8-0.70.60.8-1.1-1.5-0.0
Rest time, locomotor task time 10.30.41.7-0.70.0-0.4-0.60.0-0.20.2-0.20.3-1.2-0.6-0.0-0.7-1.3
Distance moved, locomotor task time 10.10.10.70.1-0.10.20.4-0.80.0-0.10.0-0.10.40.30.10.40.7
Vertical activity count, locomotor time 10.30.31.1-0.9-0.30.00.3-1.1-0.30.3-0.30.3-0.8-0.50.3-0.1-0.6
Time >=10cm from walls, locomotor time 21.31.42.70.21.4-1.5-1.60.31.3-1.21.3-1.2-0.11.2-1.4-1.6-0.7
Bouts of movement, locomotor time 20.40.52.01.40.20.2-0.21.10.2-0.20.2-0.21.30.6-0.20.11.1
Total resting periods, locomotor time 20.20.31.01.00.20.0-0.30.80.2-0.20.2-0.20.90.5-0.2-0.10.7
Rest time, locomotor task time 20.91.03.6-1.9-0.3-0.3-0.0-1.1-0.40.4-0.40.5-1.9-1.10.3-0.5-1.9
Distance moved, locomotor task time 20.30.31.61.30.3-0.1-0.51.10.2-0.20.2-0.10.80.5-0.3-0.40.7
Vertical activity count, locomotor time 20.80.91.60.6-1.00.90.41.3-1.21.2-1.21.3-0.1-1.21.00.20.3
Weight adjusted by age1.01.12.41.11.0-0.6-0.50.61.1-1.21.1-1.21.41.5-1.00.01.2
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.1-0.40.40.5-0.3-0.30.3-0.30.30.0-0.20.40.50.1
Locomotion in novel chamber2.02.44.7-1.81.4-1.9-1.2-2.21.4-1.41.4-1.4-1.70.9-1.4-1.2-1.9
Locomotion in novel chamber post-restriction0.70.93.3-1.60.4-0.9-0.7-0.60.2-0.20.2-0.2-1.6-0.7-0.4-1.1-1.8
Progressive ratio0.30.40.8-0.30.7-0.6-0.3-0.70.8-0.90.8-0.90.00.8-0.7-0.3-0.2
Food seeking constrained by brief footshock0.60.71.1-0.3-1.00.90.8-0.2-1.01.0-1.01.0-0.5-1.01.00.80.0
Seeking ratio, punishment vs. effort1.51.83.0-0.1-1.71.51.30.2-1.71.7-1.71.7-0.3-1.71.71.20.3
Run reversals in cocaine runway, females2.92.86.7-0.3-2.02.22.6-0.4-1.61.6-1.61.50.5-1.12.02.61.3
Run reversals in cocaine runway, males0.20.20.6-0.4-0.30.1-0.00.1-0.40.5-0.40.5-0.8-0.70.3-0.1-0.6
Latency to leave start box in cocaine runway0.40.43.6-1.20.1-0.30.3-1.90.3-0.30.3-0.4-0.4-0.0-0.10.1-0.6
Latency to leave start box in cocaine runway, F0.10.10.5-0.20.3-0.2-0.0-0.70.4-0.40.4-0.40.30.3-0.3-0.2-0.1
Latency to leave start box in cocaine runway, M1.11.03.9-2.0-0.1-0.40.2-1.8-0.20.1-0.20.1-1.8-0.90.1-0.3-1.6
Cd content in liver0.50.51.4-1.00.5-0.9-0.6-0.80.4-0.40.4-0.4-0.9-0.0-0.5-1.0-1.2
Co content in liver2.53.06.5-0.5-1.91.40.80.9-2.32.3-2.32.4-1.6-2.61.90.2-0.7
Cu content in liver0.70.81.20.5-1.01.10.90.7-1.11.0-1.01.00.5-0.91.00.80.8
Fe content in liver0.10.20.3-0.10.5-0.5-0.4-0.10.5-0.50.5-0.50.10.4-0.5-0.4-0.2
K content in liver0.50.51.40.30.6-0.30.2-0.10.9-1.00.9-1.00.91.2-0.60.50.7
Mg content in liver0.30.30.7-0.30.20.00.6-0.60.5-0.60.5-0.60.40.7-0.20.90.5
Mn content in liver0.91.12.61.40.9-0.4-0.50.81.0-1.11.0-1.11.61.4-0.9-0.01.2
Na content in liver0.80.81.80.61.0-0.7-0.60.41.1-1.21.1-1.20.91.3-1.0-0.50.4
Rb content in liver1.21.53.0-1.7-1.10.81.2-1.4-1.11.0-1.11.0-1.6-1.41.10.9-1.0
Se content in liver2.02.54.20.31.9-1.7-1.4-0.02.0-2.02.0-2.10.71.9-1.9-1.2-0.2
Sr content in liver2.22.06.82.40.9-0.2-0.81.61.0-1.01.0-1.02.61.6-0.9-0.22.1
Zn content in liver1.81.95.51.91.1-0.5-0.51.31.3-1.31.3-1.32.31.9-1.1-0.01.9