Hub : Genes

Spats2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000052307 0.09 0.09 5.2e-09 0.06 0.07 0.07 0.07 9.9e-08 4.9e-08 6.9e-08 6.3e-08
2 Adipose intron excision ratio chr7:130322428:130323680 0.04 0.05 2.9e-04 0.03 0.03 0.03 0.03 4.8e-04 3.9e-04 4.3e-04 5.2e-04
3 BLA gene expression ENSRNOG00000052307 0.24 0.16 1.1e-11 0.16 0.18 0.18 0.15 5.5e-09 4.2e-10 9.0e-10 1.9e-08
4 Brain gene expression ENSRNOG00000052307 0.13 0.08 8.3e-15 0.15 0.16 0.15 0.16 6.4e-14 1.1e-14 9.7e-14 1.0e-14
5 Brain mRNA stability ENSRNOG00000052307 0.03 0.03 1.4e-03 0.02 0.03 0.02 0.03 2.2e-03 1.6e-03 5.1e-03 1.8e-03
6 IL gene expression ENSRNOG00000052307 0.18 0.12 2.9e-04 0.17 0.15 0.09 0.15 6.7e-05 1.9e-04 2.9e-03 1.7e-04
7 LHb gene expression ENSRNOG00000052307 0.2 0.12 4.6e-05 0.16 0.15 0.12 0.15 1.6e-04 2.1e-04 7.9e-04 2.2e-04
8 Liver gene expression ENSRNOG00000052307 0.12 0.11 4.7e-11 0.08 0.08 0.08 0.08 5.4e-09 1.5e-09 4.8e-09 5.2e-09
9 NAcc gene expression ENSRNOG00000052307 0.11 0.08 7.4e-08 0.09 0.09 0.09 0.09 1.9e-07 4.6e-07 1.9e-07 2.7e-07
10 OFC gene expression ENSRNOG00000052307 0.3 0.17 3.2e-06 0.17 0.16 0.12 0.14 8.6e-05 1.2e-04 7.0e-04 2.6e-04
11 PL alternative TSS ENSRNOT00000097746 0.05 0.05 3.2e-03 0.04 0.02 0.03 0.03 9.0e-04 1.3e-02 1.9e-03 2.0e-03
12 PL gene expression ENSRNOG00000052307 0.3 0.18 0.0e+00 0.2 0.23 0.22 0.22 3.0e-15 3.8e-17 1.9e-16 2.2e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail4.314.014.83.8-3.9-3.8-3.83.8-3.7-3.63.7-3.7-3.73.8-3.5
BMI without tail0.00.00.2-0.20.10.10.0-0.20.10.3-0.2-0.20.10.00.5
Body weight6.025.526.95.1-5.2-5.1-5.25.1-5.1-4.95.0-5.0-5.15.0-4.8
Epididymis fat weight0.10.30.50.6-0.6-0.6-0.50.6-0.7-0.50.6-0.4-0.70.5-0.7
Glucose0.00.00.20.2-0.1-0.00.20.2-0.2-0.10.20.4-0.2-0.2-0.2
Heart weight0.10.10.10.3-0.3-0.3-0.40.3-0.3-0.20.3-0.3-0.30.3-0.3
Left kidney weight0.41.32.21.0-1.1-1.1-1.41.0-1.0-1.11.0-1.5-1.01.3-0.9
Right kidney weight2.67.48.12.7-2.8-2.8-2.82.7-2.6-2.82.7-2.8-2.62.7-2.6
Tail length0.10.30.5-0.60.50.60.5-0.60.60.6-0.60.30.6-0.40.7
Length with tail2.07.37.92.7-2.7-2.7-2.82.7-2.7-2.62.7-2.8-2.72.7-2.6
Length without tail7.616.617.14.1-4.1-4.1-4.14.1-4.1-4.14.1-3.8-4.13.9-4.1
Liver weight, left1.82.93.01.7-1.7-1.7-1.71.7-1.7-1.71.7-1.6-1.71.7-1.7
Liver weight, right1.52.52.81.6-1.6-1.6-1.71.6-1.5-1.51.6-1.7-1.51.6-1.5
Parametrial fat weight2.34.55.0-2.12.12.12.1-2.12.22.0-2.12.12.2-2.22.1
Retroperitoneal fat weight0.62.13.3-1.41.41.51.5-1.41.41.2-1.41.81.4-1.71.4
Intraocular pressure7.510.611.0-3.33.33.33.3-3.33.33.2-3.33.03.3-3.23.3
Extensor digitorum longus weight3.815.317.93.9-4.0-4.0-4.13.9-3.8-3.73.8-4.2-3.84.1-3.5
Soleus weight0.72.02.41.4-1.4-1.4-1.51.4-1.4-1.31.4-1.5-1.41.5-1.3
Tibialis anterior weight0.93.06.11.6-1.8-1.8-2.01.6-1.5-1.31.5-2.5-1.52.1-1.1
Tibia length6.819.320.94.5-4.6-4.5-4.34.5-4.3-4.64.5-4.0-4.34.2-4.3
Number of licking bursts0.70.91.6-0.80.80.91.1-0.80.90.8-0.81.30.9-1.10.8
Food consumed during 24 hour testing period1.72.12.61.5-1.5-1.5-1.41.5-1.4-1.61.5-1.4-1.41.4-1.4
Times rat made contact with spout0.10.10.2-0.30.30.30.3-0.30.50.4-0.40.30.5-0.40.5
Mean time between licks in bursts0.00.00.1-0.20.20.20.1-0.20.10.2-0.20.00.1-0.10.1
Mean num. licks in bursts0.10.10.50.2-0.2-0.3-0.50.2-0.2-0.20.2-0.7-0.20.5-0.2
Std. dev. time between licks in bursts1.31.61.9-1.21.21.31.3-1.21.41.0-1.21.31.4-1.31.2
Water consumed over 24 hours0.00.00.10.1-0.1-0.1-0.00.1-0.1-0.30.10.1-0.10.0-0.2
Indifference point 0 sec2.84.56.7-2.02.12.22.3-2.02.11.9-2.02.62.1-2.41.8
Indifference point AUC0.30.40.6-0.50.50.60.8-0.50.70.3-0.60.80.7-0.70.7
Indifference point function ln k4.36.17.12.4-2.4-2.5-2.52.4-2.5-2.32.4-2.7-2.52.6-2.4
Indifference point function log k4.36.17.12.4-2.4-2.5-2.52.4-2.5-2.32.4-2.7-2.52.6-2.4
Delay discounting total patch changes 0 sec2.74.36.4-1.92.02.12.3-1.92.01.9-1.92.52.0-2.31.8
Delay discounting total patch changes 12 sec2.83.75.6-1.81.82.02.2-1.82.01.6-1.82.42.0-2.21.7
Delay discounting total patch changes 18 sec5.06.68.7-2.42.52.62.9-2.42.62.2-2.42.92.6-2.82.3
Delay discounting total patch changes 24 sec2.73.44.8-1.71.71.92.1-1.71.91.6-1.72.21.9-2.01.7
Delay discounting total patch changes 6 sec3.14.86.9-2.02.12.32.5-2.02.11.8-2.02.62.1-2.41.9
Delay discounting time to switch 0 sec2.43.64.0-1.91.91.91.9-1.91.92.0-1.91.81.9-1.81.8
Delay discounting water rate 0 sec2.84.44.92.2-2.2-2.2-2.22.2-2.0-2.22.1-2.0-2.02.0-1.9
Delay discounting water rate 12 sec3.85.76.12.4-2.4-2.4-2.42.4-2.5-2.52.4-2.1-2.52.3-2.4
Delay discounting water rate 18 sec0.30.40.70.6-0.6-0.6-0.80.6-0.6-0.60.6-0.7-0.60.6-0.6
Delay discounting water rate 24 sec3.64.95.62.2-2.2-2.3-2.42.2-2.3-2.02.2-2.4-2.32.3-2.0
Delay discounting water rate 6 sec4.05.86.62.4-2.4-2.5-2.62.4-2.4-2.42.4-2.5-2.42.4-2.2
Locomotor activity1.21.82.1-1.41.41.51.2-1.41.41.2-1.41.21.4-1.31.4
Locomotor testing distance3.15.15.7-2.32.32.42.3-2.32.22.1-2.32.22.2-2.32.3
Locomotor testing rearing2.33.74.0-2.02.02.02.0-2.01.72.0-2.01.81.7-1.92.0
Light reinforcement 12.85.25.6-2.32.32.32.3-2.32.42.2-2.32.02.4-2.22.4
Light reinforcement 20.81.01.4-1.11.11.00.8-1.11.11.0-1.10.41.1-0.71.2
Reaction time number correct1.82.63.01.6-1.5-1.6-1.61.6-1.7-1.71.6-1.4-1.71.5-1.7
Reaction time mean minus median8.811.511.9-3.43.43.43.4-3.43.43.4-3.43.43.4-3.53.3
Reaction time mean minus median AUC6.28.08.4-2.82.82.82.9-2.82.82.9-2.82.82.8-2.92.7
Reaction time num false alarms1.72.42.7-1.51.51.51.6-1.51.61.5-1.51.61.6-1.61.5
Reaction time num false alarms AUC2.43.33.6-1.81.81.81.8-1.81.91.8-1.81.81.9-1.91.7
Reaction time trials correct on left1.82.63.01.6-1.5-1.6-1.61.6-1.7-1.71.6-1.4-1.71.5-1.7
Reaction time trials on left1.42.02.41.4-1.4-1.4-1.41.4-1.6-1.51.4-1.3-1.61.3-1.5
Reaction time mean0.81.01.2-1.01.01.11.1-1.00.91.1-1.01.10.9-1.11.0
Reaction time mean AUC0.40.60.8-0.70.70.80.8-0.70.60.9-0.80.80.6-0.80.8
Median of all reaction times0.00.00.00.0-0.00.00.10.0-0.20.00.00.1-0.2-0.0-0.0
Reaction time omissions10.013.414.1-3.73.73.83.7-3.73.63.6-3.73.53.6-3.63.6
Reaction time false alarm rate2.94.14.7-2.02.02.02.0-2.02.22.1-2.01.92.2-2.02.0
Reaction time premature initiation rate6.68.910.1-3.13.03.02.9-3.13.02.9-3.12.63.0-2.93.2
Reaction time premature initiations2.83.94.6-2.12.12.12.0-2.11.91.9-2.11.71.9-1.92.1
Std. dev. reaction times6.58.99.5-3.03.03.03.1-3.02.83.1-3.03.02.8-3.12.9
Reaction time trials completed1.42.02.41.4-1.4-1.4-1.41.4-1.6-1.51.4-1.3-1.61.3-1.5
Reaction time trials AUC2.23.23.71.8-1.7-1.8-1.81.8-1.9-1.81.8-1.6-1.91.7-1.9
Social response proportion0.20.20.4-0.40.40.40.3-0.40.60.4-0.40.40.6-0.40.5
Social responses8.410.811.5-3.33.33.33.2-3.33.43.2-3.33.23.4-3.33.3
Social time0.00.00.10.0-0.0-0.1-0.40.0-0.10.10.0-0.4-0.10.30.0
Conditioned locomotion0.00.00.10.2-0.1-0.1-0.00.2-0.2-0.30.20.2-0.2-0.0-0.3
Cocaine response after cond. corrected0.00.00.0-0.00.0-0.0-0.1-0.00.00.2-0.0-0.10.00.10.1
Cocaine response after cond. not corrected0.50.50.7-0.80.70.70.6-0.80.70.9-0.80.50.7-0.60.8
Cocaine response before conditioning3.34.04.3-2.02.02.02.1-2.02.01.9-2.01.92.0-2.02.0
Saline control response0.10.10.30.4-0.4-0.4-0.20.4-0.4-0.50.4-0.0-0.40.2-0.5
Condit. Reinf. active minus inactive responses0.00.00.0-0.10.0-0.0-0.0-0.10.10.0-0.1-0.20.10.00.2
Condit. Reinf. active-inactive response ratio0.30.30.5-0.60.50.40.4-0.60.60.6-0.60.10.6-0.30.7
Condit. Reinf. active responses0.10.20.3-0.50.40.40.4-0.50.50.4-0.50.20.5-0.40.5
Condit. Reinf. inactive responses0.60.70.8-0.90.90.90.8-0.90.80.8-0.80.80.8-0.80.8
Condit. Reinf. lever presses0.00.00.00.00.0-0.00.10.0-0.0-0.00.00.1-0.0-0.0-0.0
Condit. Reinf. lever reinforcers received0.50.60.7-0.80.80.80.8-0.80.80.8-0.80.70.8-0.80.8
Pavlov. Cond. lever latency0.10.10.50.2-0.2-0.3-0.60.2-0.1-0.20.2-0.7-0.10.5-0.1
Pavlov. Cond. magazine entry latency0.91.11.61.1-1.1-1.0-0.71.1-1.1-1.21.1-0.4-1.10.7-1.3
Pavlov. Cond. change in total contacts1.11.51.81.3-1.3-1.2-1.01.3-1.3-1.21.3-0.9-1.31.1-1.2
Pavlov. Cond. index score0.30.40.70.8-0.7-0.6-0.20.8-0.8-0.70.80.1-0.80.3-0.8
Pavlov. Cond. latency score0.40.50.70.8-0.7-0.6-0.30.8-0.8-0.80.80.0-0.80.3-0.9
Pavlov. Cond. lever contacts0.20.30.7-0.40.50.50.8-0.40.40.5-0.50.80.4-0.70.4
Pavlov. Cond. magazine entry number1.82.23.0-1.61.51.41.1-1.61.61.7-1.60.81.6-1.11.7
Pavlov. Cond. intertrial magazine entries5.26.77.5-2.62.62.62.5-2.62.72.7-2.72.22.7-2.42.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.21.0-1.0-0.9-0.51.0-1.1-1.01.0-0.2-1.10.6-1.1
Pavlov. Cond. response bias0.00.10.3-0.10.10.20.4-0.10.10.1-0.10.50.1-0.40.0
Conditioned reinforcement - actives1.61.61.9-1.31.31.31.3-1.31.31.1-1.31.11.3-1.11.4
Conditioned reinforcement - inactives2.32.63.4-1.61.61.61.7-1.61.81.3-1.61.51.8-1.51.6
Conditioned locomotion0.40.50.6-0.70.70.70.7-0.70.70.5-0.70.80.7-0.80.7
Intermittent access intake day 1-15 change1.51.52.0-1.31.31.21.2-1.31.31.1-1.31.11.3-1.11.4
Intermittent access intake escalation1.11.01.5-1.11.01.01.0-1.11.10.9-1.10.71.1-0.81.2
Intermittent access intake escalation 21.71.72.2-1.41.31.31.3-1.41.41.2-1.40.91.4-1.01.5
Intermitt. access day 1 inactive lever presses2.12.23.4-1.61.61.51.3-1.61.61.8-1.61.01.6-1.01.5
Intermitt. access day 15 inactive lever presses1.11.31.8-1.21.11.00.9-1.21.31.2-1.20.81.3-1.01.2
Intermitt. access escalation Index0.20.20.6-0.50.50.50.5-0.50.40.8-0.50.40.4-0.20.3
Intermittent access day 1 total infusions1.21.41.8-1.21.21.21.2-1.21.31.1-1.21.01.3-0.81.2
Intermittent access day 15 total infusions2.93.33.8-1.91.81.91.9-1.92.01.6-1.91.62.0-1.41.9
Intermittent access terminal intake (last 3 days)3.13.44.0-1.91.91.91.9-1.92.01.7-1.91.62.0-1.51.9
Intermittent access total infusions2.83.13.6-1.81.81.81.8-1.81.91.6-1.81.41.9-1.31.9
Intermittent access day 1 locomotion0.90.91.1-1.01.01.01.0-1.01.01.0-0.90.91.0-0.80.9
Intermittent access day 15 total locomotion1.81.92.3-1.41.41.41.4-1.41.51.1-1.41.41.5-1.41.4
Intermittent access total locomotion3.74.14.6-2.02.12.12.1-2.02.11.9-2.02.12.1-1.91.9
Intermittent access standard deviation0.50.60.8-0.80.70.70.6-0.80.90.8-0.80.40.9-0.40.9
Cocaine induced anxiety1.31.52.91.1-1.1-1.1-1.21.1-1.1-1.21.1-1.6-1.11.7-1.1
Post-drug Anxiety5.56.18.52.4-2.4-2.5-2.52.4-2.3-2.42.4-2.9-2.32.9-2.3
Baseline Anxiety0.91.01.01.0-1.0-1.0-1.01.0-1.0-0.81.0-0.9-1.01.0-1.0
Lifetime Intake2.93.23.8-1.81.81.91.9-1.81.91.6-1.81.61.9-1.41.9
Incentive Sensitization - Responses0.00.00.30.0-0.1-0.1-0.00.00.1-0.20.0-0.40.10.50.1
Incentive Sensitization - Breakpoint0.00.00.1-0.10.10.10.1-0.10.2-0.1-0.1-0.30.20.40.2
Progressive ratio test 1 active lever presses5.35.56.8-2.32.42.52.6-2.32.32.2-2.32.42.3-2.12.2
Progressive ratio test 1 breakpoint4.95.06.2-2.22.32.42.5-2.22.22.1-2.22.32.2-2.12.1
Progressive ratio test 1 inactive lever presses3.53.84.4-2.02.02.01.9-2.02.12.0-2.01.62.1-1.32.0
Progressive ratio test 2 active lever presses2.62.83.3-1.71.71.71.8-1.71.71.7-1.71.41.7-1.21.7
Progressive ratio test 2 breakpoint3.23.64.2-2.02.02.02.0-2.01.91.9-2.01.61.9-1.42.0
Progressive ratio test 2 inactive lever presses2.52.93.4-1.81.81.71.7-1.81.91.6-1.81.31.9-1.21.8
Total sessions with >9 infusions1.41.52.0-1.21.21.31.4-1.21.30.9-1.21.31.3-1.21.3
Short access day 1 total inactive lever presses1.61.82.2-1.41.41.41.4-1.41.31.5-1.41.21.3-1.21.4
Short access day 10 total inactive lever presses0.20.20.5-0.40.40.30.1-0.40.40.7-0.40.30.4-0.50.3
Short access day 1 total infusions0.10.10.3-0.30.40.40.5-0.30.30.2-0.30.50.3-0.40.4
Short access day 10 total infusions1.51.62.2-1.21.21.31.4-1.21.41.0-1.21.51.4-1.31.2
Short access total infusions0.91.01.4-0.90.91.11.2-0.91.10.7-0.91.11.1-1.01.0
Short access day 1 locomotion0.20.20.3-0.40.40.40.5-0.40.40.3-0.40.40.4-0.30.4
Short access day 10 total locomotion0.10.10.2-0.40.40.40.3-0.40.40.4-0.40.20.4-0.00.3
Short access total locomotion0.50.60.6-0.70.70.80.8-0.70.80.7-0.70.80.8-0.70.7
Compulsive drug intake1.21.11.51.1-1.1-1.2-1.21.1-1.2-0.91.1-1.0-1.20.6-1.0
One hour access (0.3 mA shock)0.30.40.7-0.70.60.60.6-0.70.70.5-0.70.20.7-0.20.9
One hour access (shock baseline)0.20.30.5-0.60.50.60.6-0.60.70.2-0.60.10.70.10.7
Number of responses in last shaping day0.00.00.10.0-0.1-0.1-0.10.0-0.2-0.10.0-0.3-0.20.30.0
Context. condit. distance diff. score0.20.30.30.5-0.5-0.5-0.60.5-0.5-0.40.5-0.5-0.50.5-0.5
Locomotion velocity, session 11.21.32.1-1.11.21.21.3-1.11.01.0-1.01.41.0-1.30.9
Locomotion distance, session 12.53.33.7-1.91.91.91.8-1.91.71.8-1.81.91.7-1.81.7
Locomotion velocity, session 20.20.20.3-0.50.50.50.6-0.50.50.4-0.50.50.5-0.50.4
Locomotion distance, session 22.23.13.6-1.81.81.81.9-1.81.71.6-1.71.91.7-1.81.6
Locomotion velocity, session 34.24.95.6-2.22.22.32.3-2.22.12.0-2.22.42.1-2.32.1
Locomotion distance, session 35.15.55.9-2.42.42.42.3-2.42.42.1-2.42.22.4-2.32.3
Stereotopy head waving bouts, day 30.91.11.61.2-1.1-1.0-0.91.2-1.0-1.31.2-0.6-1.00.8-1.2
Stereotopy head waving duration, day 30.50.60.80.9-0.8-0.7-0.60.9-0.8-0.90.9-0.4-0.80.6-0.9
Locomotion velocity, session 70.40.51.2-0.60.70.70.8-0.60.60.4-0.61.10.6-0.90.4
Locomotion distance, session 72.12.73.6-1.61.61.71.8-1.61.61.4-1.61.91.6-1.81.4
Stereotopy head waving bouts, day 70.80.91.31.0-1.0-0.9-0.91.0-0.9-1.21.0-0.8-0.90.8-0.9
Stereotopy head waving duration, day 71.11.41.71.2-1.3-1.2-1.21.2-1.2-1.31.2-1.1-1.21.1-1.1
Locomotion velocity, session 80.00.00.10.0-0.00.00.10.0-0.20.00.10.4-0.2-0.1-0.1
Locomotion distance, session 81.11.61.8-1.31.31.31.3-1.31.11.3-1.31.31.1-1.31.1
Degree of sensitization distance0.40.40.50.7-0.6-0.6-0.60.7-0.7-0.60.7-0.4-0.70.6-0.7
Degree of sensitization stereotypy0.10.20.30.4-0.5-0.4-0.40.4-0.3-0.50.4-0.5-0.30.4-0.2
Condit. Reinf. active minus inactive responses0.00.00.1-0.20.20.30.2-0.20.20.2-0.20.20.2-0.20.2
Condit. Reinf. active-inactive response ratio0.30.30.40.5-0.5-0.5-0.50.5-0.6-0.50.5-0.5-0.60.5-0.6
Condit. Reinf. active responses0.60.70.9-0.80.90.90.9-0.80.80.9-0.80.90.8-0.90.8
Condit. Reinf. inactive responses2.93.43.7-1.81.91.91.9-1.81.81.9-1.81.91.8-1.91.8
Incentive salience index mean0.00.00.00.1-0.1-0.1-0.10.1-0.1-0.10.1-0.1-0.10.1-0.1
Condit. Reinf. lever presses0.10.20.30.3-0.4-0.4-0.40.4-0.3-0.30.3-0.6-0.30.5-0.2
Time in familiar zone, hab. session 10.20.20.4-0.50.50.40.3-0.50.50.6-0.50.30.5-0.40.5
Time in novel zone, hab. session 10.20.20.30.5-0.5-0.4-0.40.5-0.5-0.50.5-0.3-0.50.4-0.5
Total zone transitions, hab. session 10.30.40.5-0.70.70.60.6-0.70.60.7-0.70.50.6-0.60.7
Total locomotion distance, hab. session 10.00.00.10.1-0.0-0.00.10.1-0.2-0.20.10.3-0.2-0.1-0.3
Locomotion velocity, hab. session 10.00.00.10.2-0.1-0.1-0.00.2-0.3-0.30.20.1-0.30.0-0.4
Time in familiar zone, hab. session 20.50.50.80.6-0.7-0.7-0.80.6-0.7-0.60.6-0.9-0.70.8-0.6
Time in novel zone, hab. session 20.40.40.8-0.50.60.70.7-0.50.50.5-0.50.90.5-0.70.4
Total zone transitions, hab. session 20.30.40.4-0.60.60.60.6-0.60.60.6-0.60.60.6-0.60.6
Total locomotion distance, hab. session 20.10.10.3-0.30.30.30.5-0.30.30.2-0.30.50.3-0.40.2
Locomotion velocity, hab. session 20.00.00.1-0.10.20.20.3-0.10.10.1-0.10.30.1-0.20.0
Novel to familiar place preference ratio1.71.81.91.4-1.4-1.4-1.31.4-1.3-1.11.4-1.3-1.31.3-1.3
Novelty place preference1.21.21.31.2-1.1-1.1-1.11.2-1.2-0.91.2-1.0-1.21.1-1.2
Time in novel zone, NPP test1.01.01.21.0-1.0-1.0-1.01.1-1.1-0.81.0-0.8-1.11.0-1.1
Total zone transitions, NPP test1.42.02.5-1.41.41.51.5-1.41.31.3-1.41.61.3-1.51.3
Total locomotion distance, NPP test1.72.43.5-1.51.61.61.7-1.51.51.4-1.51.91.5-1.71.3
Locomotion velocity, NPP test1.01.42.2-1.11.21.21.4-1.11.11.0-1.11.51.1-1.31.0
Pavlov. Cond. lever latency0.20.20.60.4-0.3-0.4-0.40.4-0.6-0.30.5-0.1-0.60.3-0.8
Pavlov. Cond. magazine entry latency0.00.10.30.1-0.1-0.2-0.30.1-0.1-0.10.1-0.6-0.10.30.0
Pavlov. Cond. change in total contacts0.00.00.30.1-0.2-0.2-0.20.10.1-0.10.0-0.50.10.30.2
Pavlov. Cond. index score0.00.00.10.0-0.1-0.1-0.10.00.1-0.1-0.0-0.40.10.10.3
Pavlov. Cond. latency score0.00.00.2-0.1-0.00.00.0-0.10.2-0.0-0.1-0.20.20.00.4
Pavlov. Cond. lever contacts0.60.71.3-0.80.70.80.7-0.80.90.8-0.90.40.9-0.61.2
Pavlov. Cond. magazine entry number0.00.00.10.2-0.1-0.1-0.00.2-0.2-0.20.20.2-0.2-0.0-0.3
Pavlov. Cond. intertrial magazine entries0.50.61.8-0.60.70.81.0-0.60.50.6-0.61.40.5-1.00.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.3-0.4-0.4-0.40.3-0.2-0.40.3-0.7-0.20.5-0.0
Pavlov. Cond. response bias0.10.10.2-0.30.30.20.2-0.30.40.3-0.3-0.10.4-0.10.5
Bone: apparent density10.517.417.94.2-4.2-4.2-4.14.2-4.1-4.24.2-4.0-4.14.1-4.2
Bone surface12.221.522.54.7-4.7-4.7-4.64.7-4.5-4.74.7-4.5-4.54.6-4.6
Bone volume9.315.816.54.0-4.0-4.0-4.04.0-3.8-4.14.0-3.9-3.83.9-3.9
Bone: connectivity density7.411.612.43.5-3.5-3.4-3.33.5-3.4-3.53.5-3.1-3.43.3-3.5
Bone: cortical apparent density0.30.40.5-0.60.60.60.5-0.60.70.7-0.60.50.7-0.50.6
Bone: cortical area9.113.815.23.8-3.8-3.7-3.63.8-3.7-3.93.8-3.5-3.73.6-3.6
Bone: cortical porosity0.50.50.7-0.80.80.70.6-0.80.70.6-0.80.50.7-0.60.7
Bone: cortical porosity0.90.91.1-1.11.11.00.8-1.11.00.8-1.00.71.0-0.91.0
Bone: cortical thickness3.04.95.62.3-2.4-2.2-2.12.3-2.2-2.42.3-2.0-2.22.1-2.1
Bone: cortical thickness0.00.00.10.3-0.3-0.2-0.00.3-0.2-0.30.30.1-0.20.0-0.2
Bone: cortical tissue density0.40.50.6-0.70.70.70.6-0.70.80.8-0.70.60.8-0.60.7
Bone: elastic displacement4.34.85.7-2.22.32.32.3-2.22.02.4-2.22.42.0-2.21.9
Bone: elastic work0.00.10.10.1-0.1-0.2-0.30.1-0.30.00.2-0.3-0.30.3-0.3
Bone: endosteal estimation8.217.718.24.2-4.2-4.3-4.24.2-4.2-4.24.2-4.2-4.24.2-4.2
Bone: endosteal perimeter6.813.914.73.8-3.8-3.8-3.73.8-3.7-3.83.7-3.7-3.73.7-3.6
Bone: final force10.717.518.44.2-4.2-4.3-4.34.2-4.1-4.14.1-4.3-4.14.3-4.0
Bone: final moment11.518.920.24.3-4.4-4.4-4.54.3-4.3-4.24.3-4.5-4.34.5-4.2
Bone: marrow area8.017.217.74.2-4.2-4.2-4.24.2-4.1-4.24.2-4.1-4.14.1-4.1
Bone: maximum diameter3.25.97.22.5-2.6-2.4-2.32.5-2.4-2.72.5-2.1-2.42.2-2.4
Bone: maximum force15.527.028.15.2-5.2-5.3-5.35.2-5.2-5.15.2-5.3-5.25.3-5.1
Bone: maximum moment16.428.630.25.3-5.3-5.4-5.55.3-5.3-5.25.3-5.5-5.35.5-5.2
Bone: minimum diameter9.317.117.74.2-4.2-4.2-4.24.2-4.1-4.24.1-4.1-4.14.1-4.0
Bone: periosteal estimation11.924.426.15.0-5.0-5.0-4.95.0-4.9-5.15.0-4.8-4.94.9-4.8
Bone: periosteal perimeter10.216.917.94.2-4.2-4.2-4.14.2-4.1-4.24.1-4.0-4.14.0-4.0
Bone: post-yield work9.512.913.43.5-3.6-3.6-3.73.5-3.6-3.53.6-3.6-3.63.6-3.6
Bone: stiffness18.028.430.15.3-5.4-5.4-5.55.3-5.2-5.35.3-5.5-5.25.4-5.1
Bone: tissue strength1.61.62.11.2-1.2-1.3-1.41.2-1.3-1.01.2-1.5-1.31.4-1.3
Bone: trabecular number6.710.411.23.3-3.3-3.3-3.23.3-3.2-3.33.3-2.9-3.23.1-3.3
Bone: trabecular spacing2.63.33.6-1.81.81.81.8-1.81.81.7-1.81.81.8-1.81.9
Bone: trabecular thickness0.10.10.2-0.30.30.20.0-0.30.40.4-0.3-0.30.4-0.00.4
Bone: trabecular tissue density0.00.10.2-0.30.20.10.0-0.30.40.2-0.3-0.20.40.00.4
Breakpoint value in progressive ratio session0.20.30.30.5-0.5-0.5-0.60.5-0.5-0.50.5-0.5-0.50.5-0.5
Distance traveled before self-admin1.21.21.5-1.11.21.21.1-1.11.01.1-1.11.01.0-1.21.0
Distance traveled after self-admin0.20.30.7-0.40.50.50.4-0.50.60.4-0.40.60.6-0.80.4
Delta time in closed arm before/after self-admin0.20.20.30.5-0.5-0.5-0.40.5-0.6-0.60.50.1-0.6-0.1-0.5
Delta time in open arm before/after self-admin4.34.14.5-2.12.12.12.1-2.12.12.1-2.11.82.1-1.72.0
Diff in mean of infusions in LGA sessions1.92.12.71.4-1.4-1.4-1.41.4-1.6-1.21.4-1.6-1.61.5-1.3
Extinction: sum of active levers before priming0.70.71.00.7-0.7-0.8-0.90.7-1.0-0.70.7-0.8-1.01.0-0.8
Active lever presses in extinction session 60.40.40.50.7-0.7-0.7-0.60.7-0.6-0.70.7-0.4-0.60.5-0.7
Delta distance traveled before/after self-admin0.10.10.10.3-0.3-0.3-0.30.3-0.1-0.30.3-0.1-0.1-0.1-0.3
Delta ambulatory time before/after self-admin0.00.00.10.0-0.1-0.1-0.00.00.2-0.10.00.10.2-0.30.0
Time in closed arm before self-admin1.41.61.81.3-1.3-1.3-1.41.3-1.1-1.31.3-1.3-1.11.1-1.3
Time in closed arm after self-admin0.60.60.80.9-0.9-0.9-0.90.9-0.8-0.90.9-0.3-0.80.1-0.9
Time in open arm before self-admin0.70.81.10.9-0.9-0.8-0.80.9-1.0-0.80.9-0.6-1.00.9-0.9
Time in open arm after self-admin0.20.20.4-0.50.50.50.5-0.50.40.6-0.50.20.40.20.5
Sum of active levers in priming session hrs 5-60.10.10.6-0.10.20.20.2-0.10.10.2-0.10.80.1-0.7-0.0
Time to tail flick, vehicle, before self-admin0.80.80.9-0.90.90.90.9-0.91.00.9-0.90.91.0-0.60.9
Time to tail flick, vehicle, after self-admin0.30.40.80.5-0.5-0.6-0.70.5-0.6-0.60.5-0.9-0.60.7-0.5
Time to tail flick, test, before self-admin0.20.20.3-0.50.50.40.3-0.50.40.5-0.5-0.10.4-0.30.4
Time to tail flick, test, after self-admin0.40.40.90.5-0.5-0.6-0.60.5-0.5-0.50.5-0.8-0.50.9-0.5
Delta time to tail flick, vehicle, before/after SA0.40.40.70.6-0.6-0.7-0.80.6-0.6-0.60.6-0.8-0.60.4-0.6
Delta time to tail flick, test, before/after SA0.20.10.30.4-0.4-0.4-0.40.4-0.3-0.40.4-0.2-0.30.5-0.3
Ambulatory time before self-admin3.73.94.5-2.12.12.12.0-2.11.82.1-2.01.71.8-1.91.9
Ambulatory time after self-admin2.22.43.8-1.51.51.51.5-1.51.51.4-1.51.71.5-1.91.4
Total heroin consumption1.92.32.51.5-1.5-1.5-1.61.5-1.6-1.51.5-1.5-1.61.5-1.5
Area under the delay curve1.01.11.31.0-1.0-1.0-1.01.0-1.1-1.11.0-1.2-1.11.1-0.9
Delay disc. indifference point, 0s delay1.31.42.01.2-1.2-1.2-1.21.2-1.4-1.31.2-1.1-1.40.9-1.1
Delay disc. indifference point, 16s delay0.90.91.00.9-1.0-1.0-1.00.9-1.0-0.90.9-1.0-1.00.9-0.8
Delay disc. indifference point, 2s delay1.71.92.71.3-1.3-1.4-1.41.3-1.4-1.31.3-1.6-1.41.6-1.3
Delay disc. indifference point, 24s delay1.31.31.41.2-1.2-1.1-1.11.2-1.2-1.21.1-1.1-1.21.2-1.1
Delay disc. indifference point, 4s delay0.40.40.70.5-0.6-0.6-0.70.5-0.7-0.50.5-0.8-0.70.7-0.5
Delay disc. indifference point, 8s delay2.52.63.21.6-1.6-1.6-1.61.6-1.6-1.81.6-1.6-1.61.7-1.5
Delay discount exponential model param0.91.01.4-0.91.01.01.0-0.91.01.0-0.91.21.0-1.20.8
Delay discount hyperbolic model param1.01.01.5-0.91.01.01.0-0.91.01.0-0.91.21.0-1.20.9
Fecal boli incidents, locomotor time 12.12.32.5-1.61.61.61.6-1.61.51.6-1.61.31.5-1.21.6
Change in fecal boli incidents, locomotor task1.61.51.81.2-1.2-1.2-1.31.2-1.2-1.41.3-1.1-1.21.2-1.3
Time >=10cm from walls, locomotor time 10.10.10.20.4-0.3-0.3-0.20.4-0.3-0.30.40.1-0.30.0-0.4
Bouts of movement, locomotor time 10.00.00.10.1-0.1-0.1-0.10.1-0.10.00.10.2-0.1-0.3-0.1
Total resting periods, locomotor time 10.20.30.8-0.40.40.40.4-0.40.30.6-0.40.80.3-0.90.3
Rest time, locomotor task time 10.60.61.1-0.60.60.70.6-0.61.00.8-0.61.01.0-1.00.6
Distance moved, locomotor task time 10.00.00.10.2-0.2-0.2-0.10.2-0.2-0.30.2-0.0-0.2-0.0-0.2
Vertical activity count, locomotor time 11.51.62.21.2-1.2-1.1-1.01.2-1.4-1.41.2-1.4-1.41.5-1.1
Time >=10cm from walls, locomotor time 20.50.50.8-0.80.80.80.8-0.80.70.6-0.80.50.7-0.40.9
Bouts of movement, locomotor time 22.72.93.31.7-1.7-1.8-1.81.7-1.8-1.71.7-1.6-1.81.5-1.6
Total resting periods, locomotor time 23.03.23.61.8-1.8-1.9-1.91.8-1.9-1.81.8-1.7-1.91.6-1.7
Rest time, locomotor task time 20.00.00.10.1-0.0-0.0-0.00.10.20.10.10.40.2-0.4-0.1
Distance moved, locomotor task time 20.00.00.1-0.20.20.20.2-0.20.30.1-0.20.10.3-0.10.2
Vertical activity count, locomotor time 20.00.00.20.1-0.1-0.1-0.00.1-0.1-0.40.1-0.3-0.10.40.0
Weight adjusted by age1.92.22.31.5-1.5-1.4-1.41.5-1.5-1.51.5-1.5-1.51.5-1.4
Seeking ratio, delayed vs. immediate footshock0.30.30.40.6-0.6-0.6-0.50.6-0.5-0.60.6-0.6-0.50.5-0.5
Locomotion in novel chamber0.60.81.40.8-0.9-1.0-0.90.8-0.8-0.80.8-1.2-0.81.1-0.6
Locomotion in novel chamber post-restriction0.00.10.30.1-0.2-0.2-0.20.2-0.2-0.20.1-0.6-0.20.2-0.1
Progressive ratio0.10.10.3-0.20.30.40.5-0.20.50.1-0.20.40.5-0.40.2
Food seeking constrained by brief footshock0.40.50.8-0.70.70.80.8-0.70.70.7-0.70.90.7-0.80.6
Seeking ratio, punishment vs. effort0.00.00.0-0.10.0-0.0-0.1-0.1-0.10.2-0.1-0.1-0.10.00.0
Run reversals in cocaine runway, females0.00.00.10.0-0.1-0.2-0.20.0-0.10.10.0-0.2-0.10.30.1
Run reversals in cocaine runway, males1.61.61.9-1.21.21.21.3-1.21.21.2-1.21.41.2-1.31.3
Latency to leave start box in cocaine runway0.00.00.1-0.10.10.10.0-0.10.00.1-0.10.20.0-0.30.2
Latency to leave start box in cocaine runway, F1.71.92.1-1.41.41.41.3-1.41.21.3-1.41.41.2-1.41.4
Latency to leave start box in cocaine runway, M1.91.82.21.4-1.5-1.4-1.41.4-1.4-1.41.4-1.2-1.41.0-1.3
Cd content in liver0.80.91.1-0.90.90.91.1-0.90.90.9-0.91.00.9-1.01.0
Co content in liver0.80.91.4-0.90.91.00.9-0.91.00.9-1.00.91.0-1.01.2
Cu content in liver0.60.71.20.8-0.8-0.8-0.80.8-1.1-0.60.8-0.6-1.10.8-0.9
Fe content in liver0.50.60.9-0.70.70.80.8-0.70.61.0-0.70.80.6-0.70.7
K content in liver0.10.10.20.4-0.4-0.3-0.30.4-0.3-0.40.4-0.0-0.30.2-0.4
Mg content in liver0.10.10.2-0.10.10.20.3-0.10.30.0-0.20.40.3-0.40.2
Mn content in liver0.10.10.10.3-0.3-0.4-0.30.3-0.3-0.30.3-0.4-0.30.3-0.4
Na content in liver0.10.10.2-0.30.30.30.3-0.30.30.4-0.30.40.3-0.30.2
Rb content in liver0.70.81.6-0.80.80.91.1-0.80.80.8-0.81.30.8-1.10.7
Se content in liver1.01.22.1-0.91.01.11.3-0.91.00.9-0.91.41.0-1.30.9
Sr content in liver0.10.10.40.4-0.5-0.3-0.10.4-0.3-0.60.4-0.1-0.30.2-0.3
Zn content in liver2.42.63.1-1.61.61.71.7-1.61.61.6-1.61.81.6-1.71.6