Hub : Genes

Giot1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000051563 0.32 0.16 0.0e+00 0.34 0.34 0.34 0.34 9.3e-39 9.1e-39 6.6e-39 8.0e-39
2 Adipose intron excision ratio chr7:10222143:10222350 0.03 0.02 2.0e-03 0.02 0.02 0.01 0.01 4.2e-03 5.9e-03 1.0e-02 1.2e-02
3 BLA gene expression ENSRNOG00000051563 0.48 0.17 0.0e+00 0.51 0.53 0.52 0.54 1.6e-31 6.5e-33 1.9e-32 6.6e-34
4 Brain gene expression ENSRNOG00000051563 0.32 0.13 0.0e+00 0.39 0.4 0.4 0.4 1.1e-38 3.2e-39 2.1e-39 4.2e-39
5 Brain intron excision ratio chr7:10196371:10215481 0.04 0.03 1.9e-04 0.03 0.04 0.03 0.03 4.9e-04 2.2e-04 3.7e-04 4.2e-04
6 IL gene expression ENSRNOG00000051563 0.3 0.18 1.4e-05 0.12 0.13 0.22 0.13 6.8e-04 4.2e-04 6.7e-06 5.2e-04
7 IL intron excision ratio chr7:10222143:10222350 0.14 0.13 9.2e-03 0.06 0.05 0.06 0.05 1.2e-02 2.3e-02 1.7e-02 2.0e-02
8 LHb gene expression ENSRNOG00000051563 0.34 0.17 1.1e-07 0.24 0.27 0.25 0.24 1.8e-06 3.9e-07 1.3e-06 1.6e-06
9 Liver gene expression ENSRNOG00000051563 0.16 0.1 0.0e+00 0.17 0.17 0.17 0.17 3.2e-18 1.8e-18 2.0e-18 3.2e-18
10 NAcc gene expression ENSRNOG00000051563 0.37 0.15 0.0e+00 0.44 0.46 0.46 0.46 4.3e-36 2.1e-37 2.7e-37 1.7e-37
11 NAcc intron excision ratio chr7:10222143:10222350 0.07 0.05 3.8e-06 0.09 0.08 0.08 0.08 5.7e-07 2.7e-06 1.6e-06 1.4e-06
12 OFC gene expression ENSRNOG00000051563 0.5 0.2 1.1e-09 0.28 0.31 0.3 0.31 2.3e-07 4.3e-08 7.0e-08 5.1e-08
13 PL gene expression ENSRNOG00000051563 0.46 0.18 0.0e+00 0.48 0.5 0.5 0.49 2.3e-40 8.3e-43 2.5e-43 5.4e-42
14 PL intron excision ratio chr7:10220007:10222083 0.03 0.03 1.4e-03 0.03 0.03 0.03 0.03 1.6e-03 1.8e-03 1.4e-03 2.2e-03
15 PL intron excision ratio chr7:10222143:10222350 0.03 0.02 4.0e-03 0.03 0.03 0.02 0.02 3.4e-03 3.4e-03 1.3e-02 5.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail6.320.325.84.5-4.44.44.5-4.75.1-4.64.44.34.5-4.63.94.54.6-4.5
BMI without tail1.73.55.71.9-2.02.01.6-2.02.4-1.91.71.51.7-1.91.21.81.9-1.9
Body weight1.04.46.22.2-2.22.22.0-2.22.5-2.12.01.92.1-2.11.72.12.1-2.1
Epididymis fat weight0.20.60.9-0.91.0-1.0-0.90.8-0.40.6-0.8-0.8-0.80.6-0.8-0.7-0.60.6
Glucose1.62.42.91.6-1.41.41.6-1.71.7-1.51.61.51.6-1.51.41.61.6-1.6
Heart weight0.10.20.5-0.60.7-0.7-0.40.30.30.0-0.4-0.4-0.40.0-0.5-0.20.00.1
Left kidney weight0.00.00.0-0.0-0.10.1-0.00.10.1-0.1-0.00.0-0.1-0.10.10.00.1-0.1
Right kidney weight1.13.03.9-1.91.8-1.8-1.91.9-1.61.5-1.8-1.7-2.01.5-1.6-1.7-1.51.6
Tail length3.510.711.9-3.23.0-3.1-3.43.4-3.33.3-3.3-3.3-3.43.3-3.2-3.3-3.33.2
Length with tail1.86.57.7-2.52.4-2.4-2.52.7-2.82.6-2.5-2.4-2.62.6-2.2-2.6-2.62.6
Length without tail0.00.00.1-0.10.1-0.10.00.3-0.40.2-0.00.0-0.10.20.2-0.2-0.20.3
Liver weight, left1.82.93.21.8-1.81.81.7-1.81.8-1.71.71.61.7-1.71.51.71.7-1.8
Liver weight, right1.42.42.91.6-1.71.71.5-1.51.4-1.61.51.51.4-1.61.51.51.6-1.5
Parametrial fat weight0.40.91.1-1.01.0-1.0-1.00.9-0.70.9-1.0-1.0-1.00.9-1.0-0.9-0.80.8
Retroperitoneal fat weight0.20.50.90.6-0.60.60.6-0.80.9-0.90.70.60.7-0.80.50.80.9-0.8
Intraocular pressure0.10.10.4-0.30.5-0.5-0.2-0.10.40.1-0.2-0.40.00.2-0.6-0.0-0.10.2
Extensor digitorum longus weight3.313.317.33.9-4.14.13.4-3.94.2-3.63.43.23.6-3.62.83.63.6-3.6
Soleus weight8.825.728.75.2-5.25.25.1-5.25.4-5.15.04.85.1-5.14.55.15.1-5.1
Tibialis anterior weight0.82.74.11.9-2.02.01.5-1.71.8-1.51.61.51.6-1.51.31.61.6-1.6
Tibia length0.92.62.8-1.61.5-1.5-1.71.6-1.61.6-1.6-1.6-1.61.6-1.5-1.6-1.61.6
Number of licking bursts0.00.00.3-0.10.0-0.0-0.3-0.10.30.1-0.2-0.3-0.10.1-0.5-0.1-0.10.1
Food consumed during 24 hour testing period0.50.60.80.8-0.80.80.7-0.80.9-0.80.70.60.8-0.80.50.80.8-0.8
Times rat made contact with spout0.10.10.20.3-0.30.30.1-0.40.5-0.20.10.00.2-0.2-0.20.30.2-0.2
Mean time between licks in bursts4.56.36.6-2.52.5-2.5-2.62.5-2.42.5-2.5-2.5-2.52.5-2.4-2.5-2.52.5
Mean num. licks in bursts0.10.10.10.2-0.20.20.3-0.20.1-0.30.30.30.2-0.30.30.30.3-0.2
Std. dev. time between licks in bursts0.60.80.8-0.80.8-0.8-0.90.9-0.90.9-0.9-0.8-0.90.9-0.8-0.9-0.90.9
Water consumed over 24 hours0.70.81.21.0-1.11.10.9-0.80.8-0.90.90.90.9-0.90.90.90.9-0.9
Indifference point 0 sec0.30.50.70.6-0.70.70.6-0.60.7-0.80.70.70.7-0.80.70.60.8-0.8
Indifference point AUC0.70.81.0-1.01.0-1.0-0.80.8-0.90.9-0.9-0.8-0.80.9-0.8-0.9-0.90.9
Indifference point function ln k0.20.20.30.5-0.60.50.4-0.50.5-0.50.40.40.5-0.50.30.50.5-0.4
Indifference point function log k0.20.20.30.5-0.60.50.4-0.50.5-0.50.40.40.5-0.50.30.50.5-0.4
Delay discounting total patch changes 0 sec0.20.30.40.5-0.50.50.4-0.50.6-0.60.50.50.5-0.60.50.40.6-0.6
Delay discounting total patch changes 12 sec0.30.40.50.5-0.60.60.5-0.70.7-0.70.60.50.6-0.70.40.60.7-0.7
Delay discounting total patch changes 18 sec0.91.21.5-1.21.2-1.2-1.11.1-1.11.0-1.1-1.1-1.11.0-1.0-1.1-1.01.1
Delay discounting total patch changes 24 sec0.00.00.1-0.10.2-0.20.00.1-0.30.1-0.0-0.0-0.00.10.0-0.1-0.10.1
Delay discounting total patch changes 6 sec0.00.00.2-0.40.4-0.4-0.20.2-0.0-0.1-0.1-0.1-0.2-0.1-0.0-0.20.0-0.0
Delay discounting time to switch 0 sec1.32.03.31.5-1.61.61.5-1.10.8-1.41.51.61.3-1.41.81.31.3-1.3
Delay discounting water rate 0 sec0.20.31.2-0.40.3-0.3-0.70.10.50.3-0.6-0.8-0.40.3-1.1-0.4-0.30.2
Delay discounting water rate 12 sec0.60.82.60.9-0.80.80.8-1.21.6-0.90.70.50.9-0.90.11.00.9-0.9
Delay discounting water rate 18 sec0.50.62.4-0.70.6-0.6-1.00.30.40.6-0.9-1.1-0.70.6-1.5-0.6-0.60.5
Delay discounting water rate 24 sec0.10.21.50.1-0.20.1-0.2-0.51.2-0.2-0.2-0.40.1-0.2-0.80.20.2-0.2
Delay discounting water rate 6 sec0.60.82.1-0.80.8-0.8-1.00.6-0.20.9-1.0-1.2-0.90.9-1.4-0.8-0.80.9
Locomotor activity2.13.35.0-1.71.6-1.6-1.82.1-2.21.9-1.8-1.6-1.91.9-1.3-1.9-1.91.8
Locomotor testing distance1.11.82.4-1.41.4-1.4-1.31.6-1.51.3-1.3-1.2-1.41.3-1.0-1.4-1.31.2
Locomotor testing rearing0.10.10.2-0.20.2-0.2-0.30.2-0.00.4-0.3-0.4-0.30.3-0.5-0.2-0.30.3
Light reinforcement 15.710.413.8-3.13.2-3.2-2.93.4-3.73.4-3.1-2.9-3.13.4-2.6-3.2-3.53.3
Light reinforcement 21.72.33.6-1.51.5-1.5-1.31.6-1.91.7-1.4-1.3-1.31.7-1.1-1.6-1.71.5
Reaction time number correct0.10.20.90.4-0.40.40.2-0.70.9-0.40.20.10.4-0.4-0.20.40.4-0.4
Reaction time mean minus median0.70.91.1-1.01.0-1.0-1.00.9-0.50.8-1.0-1.0-1.00.8-1.1-0.9-0.80.8
Reaction time mean minus median AUC0.00.00.00.1-0.00.00.10.10.0-0.10.10.1-0.0-0.10.20.10.1-0.1
Reaction time num false alarms0.00.00.20.1-0.30.3-0.2-0.20.20.2-0.1-0.20.10.2-0.4-0.1-0.20.2
Reaction time num false alarms AUC0.00.00.20.2-0.30.3-0.2-0.20.30.1-0.1-0.20.10.1-0.5-0.1-0.10.1
Reaction time trials correct on left0.10.20.90.4-0.40.40.2-0.70.9-0.40.20.10.4-0.4-0.20.40.4-0.4
Reaction time trials on left0.20.20.90.4-0.50.50.2-0.71.0-0.40.30.10.4-0.5-0.20.50.5-0.4
Reaction time mean0.10.10.10.3-0.20.20.4-0.30.4-0.30.30.30.2-0.30.30.30.4-0.3
Reaction time mean AUC0.20.20.30.4-0.30.30.5-0.40.5-0.50.50.50.4-0.50.50.50.5-0.5
Median of all reaction times0.50.70.80.9-0.80.80.9-0.80.7-0.80.80.90.8-0.80.90.80.8-0.8
Reaction time omissions0.00.10.3-0.40.5-0.5-0.10.2-0.20.1-0.1-0.1-0.20.1-0.0-0.1-0.10.1
Reaction time false alarm rate0.00.00.10.2-0.30.30.0-0.1-0.10.10.00.00.20.1-0.0-0.1-0.10.1
Reaction time premature initiation rate1.11.41.8-1.31.4-1.3-1.21.0-1.11.2-1.2-1.2-1.01.2-1.3-1.1-1.21.2
Reaction time premature initiations0.91.32.2-1.21.2-1.2-1.20.8-0.61.1-1.2-1.3-0.91.1-1.5-1.0-1.11.1
Std. dev. reaction times0.10.10.2-0.40.5-0.5-0.40.3-0.10.3-0.4-0.4-0.40.3-0.5-0.4-0.20.2
Reaction time trials completed0.20.20.90.4-0.50.50.2-0.71.0-0.40.30.10.4-0.5-0.20.50.5-0.4
Reaction time trials AUC0.10.20.90.3-0.40.40.1-0.60.9-0.30.20.00.3-0.4-0.30.40.4-0.3
Social response proportion0.40.40.7-0.70.8-0.8-0.60.7-0.80.5-0.5-0.5-0.70.5-0.3-0.6-0.50.6
Social responses5.77.48.9-2.82.8-2.8-2.72.9-3.02.7-2.7-2.5-2.82.7-2.3-2.7-2.72.6
Social time0.91.11.31.0-0.80.81.2-1.01.1-1.11.11.11.0-1.11.11.11.1-1.1
Conditioned locomotion0.80.91.81.0-1.01.00.8-1.21.3-0.90.80.71.0-0.90.50.90.9-1.0
Cocaine response after cond. corrected4.14.67.02.1-2.12.12.0-2.52.6-2.22.01.82.2-2.21.42.22.2-2.3
Cocaine response after cond. not corrected4.14.67.12.1-2.12.12.0-2.52.7-2.22.01.82.2-2.21.42.22.2-2.2
Cocaine response before conditioning0.70.80.9-0.80.7-0.7-0.91.0-1.00.9-0.9-0.9-1.00.9-0.8-1.0-0.91.0
Saline control response0.00.00.10.2-0.20.20.2-0.30.4-0.20.20.20.2-0.20.10.20.2-0.2
Condit. Reinf. active minus inactive responses2.12.63.3-1.71.8-1.8-1.71.4-1.21.5-1.7-1.7-1.61.5-1.8-1.6-1.51.6
Condit. Reinf. active-inactive response ratio0.10.10.3-0.20.5-0.40.0-0.30.6-0.2-0.0-0.10.1-0.2-0.20.10.2-0.1
Condit. Reinf. active responses2.02.83.1-1.71.7-1.7-1.81.6-1.41.6-1.7-1.7-1.71.6-1.8-1.6-1.61.7
Condit. Reinf. inactive responses1.62.02.3-1.31.1-1.1-1.51.4-1.41.5-1.5-1.5-1.51.5-1.5-1.4-1.51.5
Condit. Reinf. lever presses2.33.23.8-1.91.9-1.9-1.81.7-1.41.7-1.8-1.8-1.71.7-1.9-1.8-1.71.7
Condit. Reinf. lever reinforcers received1.52.22.8-1.51.6-1.6-1.61.3-1.11.4-1.5-1.6-1.51.4-1.7-1.4-1.41.5
Pavlov. Cond. lever latency0.50.70.90.9-0.90.90.9-0.80.6-0.80.90.90.8-0.80.90.80.8-0.8
Pavlov. Cond. magazine entry latency0.60.70.8-0.80.7-0.7-0.90.8-0.80.9-0.9-0.9-0.90.9-0.8-0.9-0.90.9
Pavlov. Cond. change in total contacts0.40.60.9-0.80.9-0.9-0.70.7-0.50.7-0.7-0.8-0.70.7-0.8-0.7-0.70.7
Pavlov. Cond. index score0.71.01.1-1.01.0-1.0-1.00.9-0.81.0-1.0-1.0-1.01.0-1.0-1.0-1.01.0
Pavlov. Cond. latency score0.60.70.8-0.90.9-0.9-0.90.8-0.70.8-0.9-0.9-0.80.8-0.9-0.9-0.80.8
Pavlov. Cond. lever contacts0.60.91.1-1.01.0-1.0-1.00.8-0.60.9-1.0-1.0-0.90.9-1.1-0.9-0.90.9
Pavlov. Cond. magazine entry number0.91.11.21.0-0.90.91.1-1.11.0-1.11.11.11.1-1.11.01.11.1-1.1
Pavlov. Cond. intertrial magazine entries0.10.20.40.4-0.40.40.3-0.50.7-0.40.30.20.4-0.40.10.40.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.70.91.0-1.01.0-1.0-1.00.9-0.81.0-1.0-1.0-1.01.0-1.0-1.0-1.01.0
Pavlov. Cond. response bias1.72.32.8-1.61.6-1.6-1.61.4-1.21.5-1.6-1.6-1.51.5-1.7-1.5-1.51.5
Conditioned reinforcement - actives1.91.92.2-1.41.4-1.4-1.31.4-1.51.4-1.3-1.2-1.21.4-1.1-1.4-1.41.4
Conditioned reinforcement - inactives0.20.20.30.5-0.50.50.4-0.50.5-0.30.40.30.6-0.30.20.40.3-0.3
Conditioned locomotion7.28.710.5-2.92.9-2.9-2.83.0-3.23.1-2.8-2.8-2.73.1-2.6-3.0-3.13.1
Intermittent access intake day 1-15 change5.85.87.3-2.72.6-2.6-2.72.5-1.92.1-2.5-2.4-2.72.1-2.3-2.5-2.12.2
Intermittent access intake escalation5.95.97.9-2.72.7-2.7-2.82.4-1.62.0-2.6-2.6-2.72.0-2.6-2.4-2.02.1
Intermittent access intake escalation 26.76.79.0-3.02.9-3.0-3.02.6-1.72.1-2.7-2.7-2.92.1-2.7-2.6-2.12.2
Intermitt. access day 1 inactive lever presses0.20.20.4-0.50.5-0.5-0.50.3-0.30.4-0.5-0.5-0.30.4-0.6-0.4-0.40.3
Intermitt. access day 15 inactive lever presses0.70.70.8-0.90.8-0.8-0.90.9-0.70.9-0.9-0.9-0.80.9-0.9-0.8-0.90.8
Intermitt. access escalation Index0.30.30.50.6-0.60.60.7-0.40.2-0.40.60.60.5-0.40.70.50.4-0.4
Intermittent access day 1 total infusions0.10.10.40.3-0.20.20.3-0.1-0.70.40.20.20.50.40.20.0-0.40.3
Intermittent access day 15 total infusions2.52.83.2-1.61.6-1.6-1.61.6-1.81.8-1.6-1.6-1.51.8-1.6-1.6-1.81.7
Intermittent access terminal intake (last 3 days)1.21.42.1-1.11.1-1.1-1.11.1-1.41.3-1.1-1.1-1.01.3-1.0-1.2-1.31.3
Intermittent access total infusions0.40.50.9-0.50.5-0.5-0.50.6-1.00.9-0.6-0.6-0.40.9-0.6-0.6-0.90.9
Intermittent access day 1 locomotion0.80.81.6-0.80.8-0.8-0.80.8-1.31.1-0.8-0.8-0.71.1-0.8-0.9-1.11.0
Intermittent access day 15 total locomotion4.44.75.9-2.12.1-2.1-2.12.1-2.42.4-2.1-2.1-2.02.4-1.9-2.2-2.42.3
Intermittent access total locomotion1.21.42.4-1.01.0-1.0-1.01.1-1.51.4-1.0-1.0-0.91.4-0.9-1.1-1.41.3
Intermittent access standard deviation3.03.23.5-1.81.8-1.8-1.91.7-1.71.8-1.8-1.8-1.81.8-1.8-1.8-1.81.7
Cocaine induced anxiety0.20.20.6-0.40.4-0.4-0.30.6-0.80.4-0.3-0.2-0.40.40.1-0.4-0.40.5
Post-drug Anxiety0.30.31.2-0.40.5-0.5-0.30.7-1.10.7-0.4-0.3-0.50.7-0.1-0.5-0.70.7
Baseline Anxiety0.40.50.8-0.70.6-0.6-0.80.5-0.50.7-0.7-0.8-0.60.7-0.9-0.7-0.70.6
Lifetime Intake0.20.20.6-0.30.3-0.3-0.30.4-0.80.7-0.4-0.4-0.20.7-0.3-0.4-0.70.6
Incentive Sensitization - Responses0.10.10.2-0.40.4-0.4-0.30.10.5-0.1-0.2-0.2-0.2-0.1-0.3-0.20.10.1
Incentive Sensitization - Breakpoint0.10.10.2-0.50.5-0.5-0.40.20.4-0.0-0.3-0.3-0.3-0.0-0.3-0.20.00.2
Progressive ratio test 1 active lever presses0.10.10.3-0.0-0.00.0-0.10.1-0.40.5-0.2-0.30.10.5-0.4-0.2-0.50.4
Progressive ratio test 1 breakpoint0.10.10.20.1-0.10.1-0.10.0-0.40.5-0.2-0.20.10.5-0.3-0.1-0.50.3
Progressive ratio test 1 inactive lever presses0.10.10.3-0.20.2-0.2-0.20.3-0.60.5-0.3-0.3-0.10.5-0.3-0.3-0.50.3
Progressive ratio test 2 active lever presses0.20.20.4-0.50.5-0.5-0.50.4-0.10.5-0.5-0.5-0.30.5-0.6-0.5-0.50.6
Progressive ratio test 2 breakpoint0.20.20.3-0.50.5-0.5-0.50.4-0.20.4-0.5-0.5-0.30.4-0.5-0.5-0.40.5
Progressive ratio test 2 inactive lever presses0.00.00.0-0.10.1-0.1-0.00.2-0.10.2-0.1-0.00.00.20.1-0.1-0.20.1
Total sessions with >9 infusions0.00.00.10.3-0.30.30.3-0.10.1-0.00.20.30.3-0.00.30.20.00.0
Short access day 1 total inactive lever presses0.10.10.3-0.30.3-0.3-0.30.4-0.50.5-0.3-0.3-0.10.5-0.2-0.3-0.50.4
Short access day 10 total inactive lever presses0.00.00.10.0-0.00.0-0.0-0.00.1-0.10.00.00.1-0.1-0.00.10.1-0.2
Short access day 1 total infusions0.10.10.7-0.20.2-0.2-0.20.4-0.80.4-0.2-0.1-0.20.40.0-0.3-0.40.3
Short access day 10 total infusions0.50.51.2-0.40.4-0.4-0.50.5-1.11.0-0.6-0.6-0.31.0-0.7-0.6-1.00.9
Short access total infusions0.00.00.20.0-0.10.10.00.0-0.40.20.00.00.00.20.1-0.1-0.20.1
Short access day 1 locomotion0.70.81.2-0.90.9-0.9-0.81.0-1.10.9-0.8-0.8-0.90.9-0.6-0.9-0.91.0
Short access day 10 total locomotion4.14.54.9-2.22.1-2.2-2.22.1-2.12.1-2.1-2.1-2.12.1-2.1-2.2-2.12.0
Short access total locomotion1.01.01.9-0.90.8-0.9-0.91.0-1.41.1-0.9-0.9-0.91.1-0.8-1.0-1.11.1
Compulsive drug intake1.71.72.01.4-1.41.41.4-1.31.1-1.31.31.41.3-1.31.41.31.3-1.2
One hour access (0.3 mA shock)0.00.10.20.3-0.30.30.3-0.2-0.10.20.20.20.50.20.10.1-0.20.1
One hour access (shock baseline)0.50.61.0-0.60.6-0.6-0.70.5-0.91.0-0.7-0.8-0.41.0-0.9-0.7-1.00.9
Number of responses in last shaping day0.20.20.5-0.30.4-0.4-0.30.4-0.70.5-0.3-0.3-0.20.5-0.3-0.4-0.50.4
Context. condit. distance diff. score0.00.00.20.2-0.40.4-0.0-0.10.1-0.00.0-0.00.0-0.0-0.10.00.0-0.0
Locomotion velocity, session 10.10.10.5-0.40.5-0.4-0.20.5-0.70.3-0.2-0.1-0.30.30.1-0.3-0.30.3
Locomotion distance, session 10.10.21.0-0.0-0.20.1-0.00.6-1.00.3-0.10.1-0.30.30.5-0.3-0.30.3
Locomotion velocity, session 23.54.17.8-1.91.7-1.7-1.92.4-2.82.1-1.9-1.7-2.12.1-1.3-2.1-2.22.1
Locomotion distance, session 20.50.72.4-0.80.9-0.9-0.51.2-1.50.8-0.6-0.4-0.80.80.1-0.8-0.90.8
Locomotion velocity, session 38.29.510.2-3.02.9-2.9-3.23.1-3.03.1-3.1-3.1-3.13.1-3.0-3.1-3.13.1
Locomotion distance, session 30.10.10.2-0.20.1-0.2-0.40.2-0.10.3-0.3-0.4-0.30.3-0.4-0.3-0.30.3
Stereotopy head waving bouts, day 35.87.08.1-2.62.4-2.5-2.72.8-2.82.7-2.6-2.5-2.72.7-2.3-2.7-2.72.7
Stereotopy head waving duration, day 36.88.29.1-2.82.7-2.7-2.93.0-3.02.9-2.9-2.8-2.92.9-2.6-2.9-2.92.9
Locomotion velocity, session 71.41.62.0-1.00.6-0.7-1.41.3-1.21.4-1.3-1.4-1.41.4-1.4-1.4-1.41.4
Locomotion distance, session 70.00.00.20.1-0.30.3-0.2-0.20.30.0-0.1-0.2-0.00.0-0.4-0.0-0.00.0
Stereotopy head waving bouts, day 70.00.00.1-0.0-0.00.00.00.2-0.40.1-0.00.1-0.10.10.2-0.1-0.10.1
Stereotopy head waving duration, day 70.10.10.4-0.30.3-0.3-0.20.5-0.60.3-0.2-0.1-0.30.30.1-0.3-0.40.3
Locomotion velocity, session 80.60.72.0-0.60.4-0.4-0.81.1-1.41.0-0.7-0.6-1.01.0-0.3-0.9-1.01.0
Locomotion distance, session 80.20.30.9-0.40.3-0.3-0.50.7-1.00.6-0.5-0.4-0.60.6-0.2-0.6-0.60.6
Degree of sensitization distance0.30.30.60.6-0.80.80.5-0.50.5-0.50.50.50.5-0.50.40.50.5-0.5
Degree of sensitization stereotypy2.22.42.81.6-1.51.51.7-1.51.4-1.51.61.61.6-1.51.71.51.5-1.6
Condit. Reinf. active minus inactive responses5.46.06.4-2.52.4-2.4-2.52.5-2.52.5-2.4-2.4-2.52.5-2.2-2.5-2.52.5
Condit. Reinf. active-inactive response ratio2.42.63.4-1.81.8-1.8-1.61.5-1.41.5-1.6-1.6-1.51.5-1.6-1.5-1.51.5
Condit. Reinf. active responses3.74.56.3-2.12.0-2.0-2.02.3-2.52.2-2.0-1.9-2.22.2-1.6-2.2-2.22.2
Condit. Reinf. inactive responses0.50.61.7-0.70.6-0.6-0.61.0-1.30.8-0.6-0.5-0.80.8-0.2-0.8-0.80.8
Incentive salience index mean2.63.24.3-1.81.6-1.7-1.72.0-2.11.8-1.7-1.6-1.81.8-1.4-1.9-1.91.8
Condit. Reinf. lever presses0.10.10.80.3-0.40.30.40.1-0.3-0.20.40.60.2-0.20.90.20.2-0.2
Time in familiar zone, hab. session 12.62.42.7-1.61.6-1.6-1.61.5-1.41.5-1.6-1.6-1.51.5-1.6-1.5-1.51.5
Time in novel zone, hab. session 11.51.51.91.3-1.21.21.3-1.11.0-1.21.31.31.2-1.21.41.21.2-1.2
Total zone transitions, hab. session 10.60.81.9-0.80.8-0.8-0.81.2-1.40.9-0.8-0.6-1.00.9-0.3-0.9-1.01.0
Total locomotion distance, hab. session 10.81.12.8-0.90.6-0.7-0.91.4-1.71.1-0.9-0.7-1.21.1-0.4-1.1-1.21.2
Locomotion velocity, hab. session 11.31.93.9-1.20.9-1.0-1.31.7-2.01.5-1.3-1.1-1.51.5-0.7-1.5-1.51.5
Time in familiar zone, hab. session 26.87.18.5-2.82.9-2.9-2.72.6-2.42.6-2.7-2.7-2.62.6-2.7-2.6-2.62.6
Time in novel zone, hab. session 25.55.66.22.4-2.52.52.4-2.32.1-2.32.42.42.3-2.32.42.42.3-2.3
Total zone transitions, hab. session 20.50.61.80.8-0.80.80.9-0.30.0-0.60.91.00.6-0.61.40.70.6-0.6
Total locomotion distance, hab. session 20.60.71.9-0.80.8-0.8-0.71.2-1.40.9-0.7-0.6-0.90.9-0.2-0.8-0.90.9
Locomotion velocity, hab. session 20.50.61.9-0.70.7-0.7-0.61.1-1.40.8-0.6-0.4-0.80.8-0.0-0.7-0.80.8
Novel to familiar place preference ratio5.55.86.72.4-2.42.42.5-2.32.2-2.42.52.52.4-2.42.62.42.4-2.4
Novelty place preference3.53.64.41.9-1.91.92.0-1.81.7-1.92.02.01.9-1.92.11.91.9-1.9
Time in novel zone, NPP test3.63.84.42.0-2.02.02.1-1.81.7-1.92.02.01.9-1.92.12.01.9-1.9
Total zone transitions, NPP test0.10.20.80.3-0.30.30.6-0.1-0.1-0.30.50.60.3-0.30.90.40.3-0.3
Total locomotion distance, NPP test0.10.10.50.3-0.40.40.40.0-0.2-0.20.30.50.2-0.20.70.20.1-0.2
Locomotion velocity, NPP test0.00.00.30.1-0.10.10.20.2-0.40.00.20.3-0.00.00.6-0.0-0.00.0
Pavlov. Cond. lever latency0.10.10.3-0.00.4-0.30.2-0.40.6-0.30.20.10.3-0.3-0.10.30.3-0.3
Pavlov. Cond. magazine entry latency4.76.06.6-2.42.1-2.2-2.62.5-2.62.5-2.5-2.4-2.52.5-2.3-2.5-2.52.5
Pavlov. Cond. change in total contacts0.50.50.8-0.50.2-0.2-0.80.8-0.90.8-0.7-0.7-0.80.8-0.6-0.8-0.80.8
Pavlov. Cond. index score1.01.32.2-0.90.6-0.7-1.21.3-1.51.3-1.1-1.1-1.31.3-0.9-1.3-1.31.3
Pavlov. Cond. latency score0.91.22.3-0.80.5-0.5-1.11.3-1.51.2-1.0-0.9-1.21.2-0.7-1.2-1.21.2
Pavlov. Cond. lever contacts0.10.20.7-0.1-0.20.1-0.30.6-0.80.4-0.3-0.2-0.50.40.1-0.4-0.50.5
Pavlov. Cond. magazine entry number1.51.92.41.3-1.11.11.4-1.51.5-1.41.41.41.4-1.41.31.51.5-1.4
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.50.5-0.5-0.50.2-0.10.4-0.4-0.5-0.30.4-0.6-0.4-0.30.3
Pavlov. Cond. lever-magazine prob. diff.1.51.93.0-1.20.9-0.9-1.41.6-1.71.5-1.4-1.3-1.51.5-1.1-1.5-1.51.5
Pavlov. Cond. response bias2.12.63.2-1.51.2-1.3-1.71.7-1.81.7-1.6-1.6-1.71.7-1.5-1.7-1.71.7
Bone: apparent density0.61.02.80.9-0.90.91.2-0.60.3-1.01.11.30.9-1.01.70.91.0-1.0
Bone surface0.30.52.30.5-0.40.40.9-0.0-0.4-0.60.81.00.5-0.61.50.50.5-0.5
Bone volume0.40.62.60.6-0.60.61.0-0.2-0.3-0.70.91.10.6-0.71.60.60.6-0.6
Bone: connectivity density0.81.32.71.1-1.11.11.3-0.80.6-1.21.21.41.1-1.21.61.11.1-1.1
Bone: cortical apparent density1.41.82.21.2-1.01.11.4-1.41.5-1.51.31.31.4-1.51.21.41.5-1.4
Bone: cortical area0.71.11.51.2-1.21.21.1-0.90.7-1.01.11.11.0-1.01.21.01.0-1.0
Bone: cortical porosity0.20.20.5-0.50.5-0.5-0.40.6-0.70.5-0.4-0.4-0.50.5-0.2-0.5-0.50.5
Bone: cortical porosity0.00.00.20.2-0.20.20.20.1-0.2-0.10.20.30.1-0.10.50.10.1-0.1
Bone: cortical thickness1.42.42.61.6-1.61.61.6-1.51.4-1.51.61.61.5-1.51.61.51.5-1.5
Bone: cortical thickness0.00.00.2-0.10.2-0.2-0.2-0.10.30.1-0.2-0.3-0.10.1-0.4-0.1-0.00.1
Bone: cortical tissue density1.01.31.71.0-0.80.91.2-1.21.3-1.31.11.11.2-1.31.01.21.3-1.2
Bone: elastic displacement0.00.00.2-0.30.4-0.40.00.1-0.20.1-0.0-0.0-0.00.10.0-0.1-0.10.0
Bone: elastic work0.50.70.80.7-0.60.60.9-0.80.8-0.90.80.80.9-0.90.80.80.9-0.9
Bone: endosteal estimation0.10.10.30.5-0.60.60.3-0.40.3-0.30.40.40.4-0.30.30.30.3-0.4
Bone: endosteal perimeter0.30.51.1-0.60.5-0.5-0.70.8-1.10.8-0.7-0.6-0.70.8-0.5-0.8-0.80.7
Bone: final force1.32.12.91.6-1.71.71.4-1.41.3-1.41.41.41.4-1.41.41.41.4-1.4
Bone: final moment1.01.72.31.4-1.51.51.3-1.31.2-1.31.31.31.3-1.31.21.21.3-1.3
Bone: marrow area0.10.10.30.5-0.60.60.3-0.40.3-0.30.40.30.4-0.30.30.30.3-0.4
Bone: maximum diameter0.50.91.9-0.90.8-0.8-0.91.1-1.41.0-0.9-0.8-1.01.0-0.6-1.0-1.01.0
Bone: maximum force1.11.92.61.5-1.61.61.3-1.41.3-1.31.31.31.3-1.31.21.31.4-1.3
Bone: maximum moment0.91.62.11.4-1.41.41.3-1.31.2-1.31.21.21.3-1.31.21.21.3-1.3
Bone: minimum diameter0.00.00.20.0-0.20.2-0.20.2-0.40.3-0.2-0.1-0.20.3-0.1-0.2-0.30.2
Bone: periosteal estimation0.30.61.00.9-1.01.00.8-0.60.4-0.70.80.80.7-0.70.90.70.7-0.7
Bone: periosteal perimeter0.00.00.3-0.0-0.10.1-0.10.3-0.50.2-0.1-0.0-0.20.20.1-0.2-0.20.2
Bone: post-yield work0.10.20.70.6-0.80.80.2-0.40.5-0.30.30.20.3-0.30.10.30.3-0.3
Bone: stiffness2.33.65.62.2-2.42.31.8-1.91.8-1.81.81.81.8-1.81.71.81.8-1.8
Bone: tissue strength2.32.22.41.5-1.51.51.5-1.51.5-1.51.51.51.5-1.51.51.51.5-1.5
Bone: trabecular number0.20.31.1-0.50.4-0.5-0.40.8-1.10.5-0.4-0.3-0.60.50.0-0.6-0.60.6
Bone: trabecular spacing0.10.10.70.1-0.10.1-0.2-0.50.8-0.1-0.1-0.30.1-0.1-0.70.20.2-0.1
Bone: trabecular thickness1.21.44.11.1-1.01.01.5-0.70.2-1.11.31.61.1-1.12.01.01.1-1.1
Bone: trabecular tissue density1.01.41.91.3-1.41.41.1-1.31.4-1.21.11.01.1-1.20.81.21.2-1.1
Breakpoint value in progressive ratio session6.06.77.1-2.72.7-2.7-2.72.6-2.52.7-2.6-2.6-2.52.7-2.5-2.5-2.52.6
Distance traveled before self-admin1.21.31.90.9-0.90.91.0-1.01.2-1.31.11.10.9-1.31.21.11.4-1.3
Distance traveled after self-admin0.30.30.6-0.60.6-0.6-0.60.6-0.50.4-0.5-0.5-0.80.4-0.4-0.5-0.30.5
Delta time in closed arm before/after self-admin0.40.41.60.4-0.40.40.3-0.81.3-0.70.40.20.5-0.7-0.10.60.7-0.6
Delta time in open arm before/after self-admin1.71.62.21.2-1.21.21.3-1.21.2-1.31.31.31.2-1.31.41.31.3-1.5
Diff in mean of infusions in LGA sessions2.02.32.5-1.51.6-1.6-1.61.5-1.51.5-1.5-1.5-1.61.5-1.4-1.5-1.51.5
Extinction: sum of active levers before priming1.71.72.0-1.31.2-1.2-1.41.2-1.41.4-1.3-1.4-1.31.4-1.4-1.3-1.41.3
Active lever presses in extinction session 61.81.82.3-1.41.5-1.5-1.31.4-1.51.3-1.3-1.2-1.31.3-1.1-1.2-1.21.3
Delta distance traveled before/after self-admin2.22.43.0-1.41.4-1.4-1.51.6-1.71.6-1.5-1.5-1.61.6-1.4-1.5-1.61.7
Delta ambulatory time before/after self-admin2.32.53.2-1.51.4-1.4-1.51.7-1.81.7-1.6-1.5-1.61.7-1.4-1.6-1.71.8
Time in closed arm before self-admin1.21.42.21.1-1.11.11.2-0.91.0-1.31.21.31.0-1.31.51.11.4-1.2
Time in closed arm after self-admin0.00.10.2-0.20.2-0.2-0.20.00.5-0.3-0.1-0.1-0.2-0.3-0.10.00.3-0.1
Time in open arm before self-admin1.31.42.1-1.00.9-0.9-1.01.1-1.41.5-1.1-1.2-0.91.5-1.2-1.1-1.51.4
Time in open arm after self-admin0.70.81.11.0-0.90.91.0-1.00.8-0.80.90.91.1-0.80.80.90.7-0.9
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.10.10.1-0.0-0.20.10.10.10.10.10.20.1-0.00.0
Time to tail flick, vehicle, before self-admin0.50.52.3-0.40.4-0.4-0.30.7-1.51.0-0.4-0.4-0.41.0-0.2-0.6-1.00.8
Time to tail flick, vehicle, after self-admin0.30.30.6-0.70.6-0.7-0.70.40.00.3-0.6-0.7-0.60.3-0.8-0.5-0.20.3
Time to tail flick, test, before self-admin0.10.10.5-0.20.2-0.2-0.00.3-0.70.4-0.1-0.0-0.10.40.1-0.3-0.50.2
Time to tail flick, test, after self-admin0.10.20.3-0.60.5-0.5-0.50.5-0.10.1-0.4-0.4-0.60.1-0.3-0.4-0.20.3
Delta time to tail flick, vehicle, before/after SA0.40.32.10.1-0.20.20.0-0.51.4-0.80.20.10.2-0.8-0.10.40.9-0.7
Delta time to tail flick, test, before/after SA0.30.30.6-0.70.6-0.6-0.80.40.30.1-0.6-0.6-0.70.1-0.7-0.5-0.00.4
Ambulatory time before self-admin1.11.11.70.9-0.80.81.0-1.01.1-1.21.01.10.8-1.21.11.11.3-1.2
Ambulatory time after self-admin0.10.10.3-0.40.4-0.4-0.40.4-0.30.2-0.3-0.3-0.60.2-0.2-0.3-0.10.4
Total heroin consumption1.92.32.8-1.51.5-1.5-1.41.5-1.71.7-1.4-1.4-1.41.7-1.3-1.5-1.61.5
Area under the delay curve2.02.12.71.6-1.61.61.6-1.61.2-1.21.51.51.6-1.21.41.51.2-1.4
Delay disc. indifference point, 0s delay9.210.012.63.2-3.23.23.4-3.02.6-3.03.33.43.2-3.03.63.13.0-3.1
Delay disc. indifference point, 16s delay0.10.10.20.3-0.30.30.3-0.30.1-0.20.30.30.4-0.20.20.30.2-0.1
Delay disc. indifference point, 2s delay5.46.07.42.7-2.72.72.7-2.52.0-2.22.52.52.6-2.22.52.42.2-2.4
Delay disc. indifference point, 24s delay0.70.71.10.9-0.80.90.9-1.00.6-0.70.80.81.0-0.70.70.90.8-0.7
Delay disc. indifference point, 4s delay0.70.81.21.0-1.01.01.0-0.90.4-0.60.90.91.1-0.60.90.90.6-0.7
Delay disc. indifference point, 8s delay0.90.91.41.1-1.11.10.9-1.11.2-0.80.90.91.0-0.80.70.90.8-1.0
Delay discount exponential model param1.71.82.4-1.61.6-1.6-1.51.5-1.11.1-1.4-1.3-1.51.1-1.2-1.4-1.11.2
Delay discount hyperbolic model param2.62.73.5-1.91.9-1.9-1.81.8-1.41.4-1.7-1.6-1.81.4-1.5-1.7-1.41.5
Fecal boli incidents, locomotor time 11.41.52.01.3-1.41.41.2-1.31.0-1.31.21.11.2-1.31.01.31.3-1.2
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.2-0.2-0.30.3-0.50.4-0.3-0.3-0.50.4-0.2-0.4-0.40.5
Time >=10cm from walls, locomotor time 12.12.13.31.2-1.21.21.3-1.21.6-1.81.41.51.2-1.81.61.51.8-1.5
Bouts of movement, locomotor time 10.70.81.4-0.60.4-0.5-0.90.8-1.21.1-0.9-0.9-0.91.1-0.9-0.9-1.11.0
Total resting periods, locomotor time 10.70.81.4-0.70.5-0.5-0.90.8-1.21.0-0.9-0.9-0.91.0-0.9-0.9-1.01.0
Rest time, locomotor task time 10.80.91.6-0.80.5-0.5-1.01.0-1.30.9-0.9-0.9-1.20.9-0.8-0.9-0.91.0
Distance moved, locomotor task time 11.92.12.61.2-1.11.11.5-1.31.5-1.61.51.51.6-1.61.61.51.6-1.5
Vertical activity count, locomotor time 10.70.72.00.6-0.30.40.8-0.91.4-0.90.70.71.0-0.90.50.90.9-1.0
Time >=10cm from walls, locomotor time 21.71.83.21.3-1.41.41.2-1.41.8-1.41.21.21.3-1.41.01.31.5-1.4
Bouts of movement, locomotor time 20.30.30.9-0.50.5-0.5-0.40.7-1.00.7-0.4-0.3-0.40.7-0.1-0.5-0.70.6
Total resting periods, locomotor time 20.20.30.8-0.50.5-0.5-0.30.6-0.90.6-0.4-0.3-0.30.6-0.1-0.5-0.60.6
Rest time, locomotor task time 20.40.51.1-0.70.6-0.6-0.70.8-1.10.7-0.6-0.6-0.70.7-0.4-0.7-0.70.7
Distance moved, locomotor task time 20.60.61.10.8-0.80.80.8-0.91.0-0.70.80.70.9-0.70.60.80.8-0.8
Vertical activity count, locomotor time 20.50.51.60.7-0.70.70.6-0.81.3-0.80.60.50.7-0.80.30.70.8-0.8
Weight adjusted by age0.20.30.80.4-0.40.40.3-0.70.9-0.60.40.30.5-0.60.10.50.6-0.5
Seeking ratio, delayed vs. immediate footshock4.35.06.4-2.12.1-2.1-2.12.3-2.52.4-2.1-2.1-2.22.4-1.9-2.2-2.42.3
Locomotion in novel chamber0.10.10.3-0.50.5-0.5-0.50.30.20.1-0.4-0.4-0.50.1-0.5-0.3-0.10.1
Locomotion in novel chamber post-restriction1.51.82.1-1.31.2-1.2-1.41.3-1.31.3-1.4-1.4-1.31.3-1.4-1.4-1.41.5
Progressive ratio0.10.10.20.2-0.40.30.1-0.20.5-0.40.10.1-0.0-0.40.10.20.4-0.2
Food seeking constrained by brief footshock0.60.71.5-0.70.5-0.6-0.70.9-1.20.9-0.7-0.7-0.80.9-0.5-0.9-1.01.0
Seeking ratio, punishment vs. effort0.30.41.2-0.50.5-0.5-0.40.6-1.10.8-0.4-0.4-0.40.8-0.3-0.6-0.80.7
Run reversals in cocaine runway, females0.40.40.7-0.70.6-0.6-0.70.8-0.50.5-0.7-0.7-0.90.5-0.6-0.6-0.50.6
Run reversals in cocaine runway, males1.21.21.7-1.21.3-1.3-1.01.2-1.21.0-1.0-1.0-1.11.0-0.8-1.1-1.01.0
Latency to leave start box in cocaine runway0.00.10.2-0.20.4-0.40.00.2-0.0-0.20.10.2-0.1-0.20.40.00.2-0.1
Latency to leave start box in cocaine runway, F1.11.22.60.9-0.70.71.3-0.80.7-1.21.21.41.1-1.21.61.11.1-1.1
Latency to leave start box in cocaine runway, M3.12.94.2-1.81.7-1.8-2.11.7-1.11.5-1.9-1.9-1.91.5-2.0-1.7-1.41.6
Cd content in liver0.40.40.60.7-0.70.60.7-0.60.6-0.60.60.60.7-0.60.60.70.6-0.6
Co content in liver0.80.91.1-0.80.8-0.8-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.0-1.01.0
Cu content in liver0.20.20.50.6-0.70.60.5-0.20.0-0.30.50.50.4-0.30.70.40.3-0.3
Fe content in liver0.40.40.6-0.50.3-0.3-0.80.6-0.60.7-0.7-0.7-0.80.7-0.8-0.8-0.70.7
K content in liver0.10.10.30.2-0.40.4-0.10.3-0.50.2-0.1-0.0-0.20.20.2-0.3-0.30.2
Mg content in liver0.10.10.20.3-0.50.40.20.1-0.3-0.00.20.30.0-0.00.40.00.0-0.0
Mn content in liver0.70.82.4-0.60.4-0.5-0.81.2-1.61.0-0.8-0.6-1.01.0-0.3-1.0-1.01.0
Na content in liver0.70.71.81.1-1.41.30.8-0.60.3-0.60.80.90.7-0.61.00.60.6-0.6
Rb content in liver0.60.71.20.9-1.00.90.9-0.60.5-0.80.91.00.8-0.81.10.80.8-0.8
Se content in liver0.70.81.3-0.70.4-0.4-0.91.0-1.11.0-0.9-0.9-0.91.0-0.8-1.0-1.01.0
Sr content in liver0.10.10.3-0.30.3-0.3-0.40.10.00.3-0.4-0.4-0.30.3-0.6-0.3-0.30.3
Zn content in liver2.22.43.5-1.71.7-1.7-1.71.3-1.11.5-1.6-1.7-1.51.5-1.9-1.5-1.41.5