Gmps

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000051151 0.07 0.06 4.9e-07 0.04 0.03 0.03 0.03 3.0e-05 2.0e-04 4.9e-04 1.7e-04
2 BLA alternative TSS ENSRNOT00000076880 0.23 0.15 8.1e-08 0.14 0.14 0.13 0.14 5.5e-08 9.7e-08 2.5e-07 8.6e-08
3 BLA alternative TSS ENSRNOT00000084238 0.15 0.11 4.6e-05 0.09 0.08 0.08 0.09 1.2e-05 3.1e-05 6.8e-05 2.2e-05
4 BLA alternative TSS ENSRNOT00000076880 0.2 0.15 2.7e-08 0.15 0.13 0.12 0.15 1.8e-08 1.3e-07 6.4e-07 3.0e-08
5 BLA alternative TSS ENSRNOT00000084238 0.21 0.16 1.6e-08 0.15 0.14 0.14 0.15 1.2e-08 8.3e-08 7.3e-08 2.3e-08
6 BLA gene expression ENSRNOG00000051151 0.26 0.16 4.4e-10 0.16 0.15 0.15 0.17 4.0e-09 2.5e-08 1.6e-08 1.3e-09
7 BLA isoform ratio ENSRNOT00000076292 0.12 0.11 6.9e-04 0.04 0.03 0.05 0.04 2.0e-03 6.8e-03 1.6e-03 5.3e-03
8 BLA isoform ratio ENSRNOT00000084238 0.22 0.15 1.2e-05 0.07 0.06 0.08 0.07 1.1e-04 3.8e-04 5.8e-05 1.2e-04
9 Brain alternative TSS ENSRNOT00000076880 0.13 0.09 5.2e-09 0.08 0.09 0.09 0.09 6.8e-08 5.8e-09 8.6e-09 6.7e-09
10 Brain alternative TSS ENSRNOT00000076880 0.13 0.09 6.1e-10 0.09 0.1 0.1 0.11 5.7e-09 7.3e-10 5.9e-10 4.7e-10
11 Brain alternative TSS ENSRNOT00000084238 0.13 0.1 7.5e-10 0.09 0.1 0.1 0.1 7.3e-09 8.3e-10 6.4e-10 5.6e-10
12 Brain gene expression ENSRNOG00000051151 0.23 0.13 0.0e+00 0.25 0.26 0.25 0.26 6.6e-23 4.0e-24 1.8e-23 1.5e-24
13 Brain isoform ratio ENSRNOT00000076292 0.03 0.03 1.1e-03 0.03 0.03 0.02 0.02 1.7e-03 1.6e-03 4.2e-03 2.7e-03
14 Brain isoform ratio ENSRNOT00000076880 0.04 0.03 3.9e-04 0.03 0.03 0.02 0.02 8.6e-04 1.8e-03 3.3e-03 4.4e-03
15 Brain isoform ratio ENSRNOT00000084238 0.06 0.05 1.8e-06 0.06 0.06 0.06 0.06 3.0e-06 3.3e-06 1.9e-06 1.6e-06
16 LHb gene expression ENSRNOG00000051151 0.2 0.15 4.1e-03 0.01 -0 -0.01 -0 1.5e-01 3.3e-01 7.6e-01 3.9e-01
17 Liver gene expression ENSRNOG00000051151 0.1 0.06 2.4e-12 0.08 0.08 0.08 0.08 3.0e-09 2.0e-09 1.9e-09 4.6e-09
18 Liver isoform ratio ENSRNOT00000076880 0.03 0.03 1.1e-03 0.01 0.01 0.01 0.01 3.2e-02 1.5e-02 1.8e-02 4.1e-02
19 NAcc isoform ratio ENSRNOT00000076292 0.05 0.04 5.9e-04 0.03 0.03 0.03 0.03 4.1e-03 1.4e-03 1.7e-03 5.0e-03
20 NAcc isoform ratio ENSRNOT00000084238 0.05 0.04 9.0e-04 0.03 0.03 0.03 0.03 3.4e-03 1.4e-03 1.7e-03 4.5e-03
21 PL gene expression ENSRNOG00000051151 0.07 0.05 6.0e-05 0.04 0.05 0.05 0.05 2.4e-04 1.5e-04 1.8e-04 1.8e-04
22 PL mRNA stability ENSRNOG00000051151 0.04 0.03 3.8e-03 0.04 0.02 0.03 0.03 3.2e-04 7.0e-03 1.6e-03 1.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail0.51.62.3-1.5-1.21.3-1.31.31.2-1.41.3-1.1-1.11.11.3-1.3-1.31.3-1.5-1.31.2-1.31.31.2-1.1
BMI without tail0.10.31.00.50.4-0.40.4-0.4-0.41.0-1.00.60.7-0.7-0.50.40.6-0.60.50.4-0.50.4-0.4-0.50.4
Body weight0.10.40.8-0.9-0.70.6-0.60.60.6-0.80.7-0.5-0.50.50.6-0.6-0.60.6-0.9-0.60.6-0.70.70.6-0.6
Epididymis fat weight0.81.82.91.01.2-1.21.2-1.2-1.41.5-1.61.71.7-1.7-1.11.21.3-1.31.01.3-1.41.1-1.2-1.41.4
Glucose0.00.00.1-0.2-0.10.1-0.10.10.1-0.40.3-0.0-0.10.10.2-0.1-0.30.2-0.2-0.10.1-0.20.20.1-0.2
Heart weight0.70.94.01.20.2-0.40.4-0.4-0.52.0-1.81.01.0-1.1-0.80.60.9-0.81.10.5-0.90.6-0.7-0.81.1
Left kidney weight2.16.09.42.52.1-2.22.2-2.2-2.33.1-3.02.62.6-2.6-2.42.32.5-2.52.52.2-2.52.3-2.3-2.42.4
Right kidney weight1.54.27.32.31.5-1.91.9-1.9-1.82.7-2.62.12.1-2.1-2.01.92.1-2.12.11.8-2.11.9-2.0-2.02.1
Tail length1.13.45.22.01.6-1.71.7-1.7-1.72.3-2.11.71.7-1.7-1.91.82.0-1.92.01.7-1.81.8-1.8-1.81.8
Length with tail0.20.70.90.90.6-0.90.9-0.9-0.90.9-0.70.60.6-0.6-0.90.90.9-0.91.00.7-0.81.0-0.9-0.80.8
Length without tail0.20.51.5-0.8-0.60.5-0.50.50.5-1.21.2-0.8-0.80.80.5-0.5-0.70.7-0.7-0.60.7-0.50.60.7-0.7
Liver weight, left0.00.10.20.10.0-0.30.3-0.3-0.30.0-0.00.30.2-0.2-0.30.30.1-0.20.10.2-0.30.2-0.2-0.30.4
Liver weight, right0.60.91.31.00.9-0.90.9-0.9-1.10.9-0.80.90.8-0.8-1.11.01.1-1.11.00.9-1.01.1-1.0-1.01.1
Parametrial fat weight0.10.10.70.4-0.2-0.00.0-0.0-0.00.8-0.80.40.4-0.4-0.30.10.3-0.20.30.0-0.30.1-0.1-0.20.3
Retroperitoneal fat weight0.00.00.1-0.2-0.30.2-0.20.20.10.1-0.20.30.3-0.40.1-0.2-0.10.1-0.3-0.1-0.0-0.20.2-0.00.1
Intraocular pressure1.21.72.6-1.4-1.21.2-1.21.21.2-1.61.6-1.5-1.51.51.3-1.2-1.31.3-1.3-1.21.3-1.11.21.3-1.2
Extensor digitorum longus weight1.87.29.9-2.4-2.82.6-2.62.62.7-3.03.1-3.0-3.13.22.5-2.5-2.32.5-2.4-2.72.7-2.42.42.7-2.5
Soleus weight1.23.43.81.91.7-2.02.0-2.0-1.81.7-1.61.81.7-1.7-1.91.91.9-1.91.91.9-1.91.9-1.9-1.91.9
Tibialis anterior weight0.41.42.01.11.0-1.11.1-1.1-1.01.4-1.41.31.3-1.3-1.11.11.2-1.11.21.1-1.21.1-1.1-1.21.2
Tibia length0.10.30.30.60.3-0.60.6-0.6-0.40.4-0.40.50.5-0.5-0.60.50.5-0.50.50.5-0.50.6-0.5-0.50.5
Number of licking bursts2.83.34.21.81.8-1.81.8-1.8-1.82.0-2.01.91.9-1.9-1.81.81.5-1.61.81.8-1.91.8-1.8-1.91.8
Food consumed during 24 hour testing period0.10.10.3-0.4-0.30.4-0.40.40.3-0.20.1-0.1-0.10.00.4-0.4-0.60.5-0.4-0.30.3-0.40.40.3-0.4
Times rat made contact with spout2.83.25.41.71.7-1.71.7-1.7-1.82.1-2.32.12.2-2.2-1.71.61.2-1.31.71.8-1.91.6-1.6-1.91.7
Mean time between licks in bursts6.08.410.0-2.9-2.72.8-2.82.82.8-3.23.1-3.0-3.03.02.8-2.8-3.13.0-2.9-2.92.9-2.72.82.9-2.8
Mean num. licks in bursts0.50.60.7-0.8-0.80.8-0.80.80.8-0.70.7-0.7-0.60.60.8-0.8-0.80.8-0.8-0.80.7-0.80.80.7-0.8
Std. dev. time between licks in bursts3.64.35.4-2.0-2.12.1-2.12.12.1-2.22.3-2.3-2.22.22.0-2.0-1.71.9-2.0-2.12.2-2.02.02.2-2.0
Water consumed over 24 hours3.03.54.91.92.1-1.81.8-1.8-2.02.1-2.22.02.0-2.0-1.91.81.2-1.41.91.9-1.91.8-1.8-1.91.9
Indifference point 0 sec1.01.62.21.21.0-1.41.4-1.4-1.11.3-1.11.31.3-1.3-1.41.31.1-1.21.41.2-1.31.3-1.3-1.31.5
Indifference point AUC0.50.50.8-0.7-0.80.7-0.70.70.7-0.70.7-0.7-0.70.70.8-0.7-0.40.5-0.9-0.70.8-0.80.80.7-0.9
Indifference point function ln k0.00.00.1-0.2-0.1-0.00.0-0.00.0-0.30.3-0.2-0.20.20.00.0-0.40.3-0.0-0.10.10.00.00.10.1
Indifference point function log k0.00.00.1-0.2-0.1-0.00.0-0.00.0-0.30.3-0.2-0.20.20.00.0-0.40.3-0.0-0.10.10.00.00.10.1
Delay discounting total patch changes 0 sec0.61.01.40.90.7-1.01.0-1.0-0.91.0-0.91.11.0-1.0-1.11.00.9-0.91.10.9-1.01.0-1.0-1.01.2
Delay discounting total patch changes 12 sec0.91.32.61.20.7-1.01.0-1.0-0.81.4-1.31.21.2-1.2-1.11.01.6-1.41.20.9-1.11.0-1.0-1.11.0
Delay discounting total patch changes 18 sec1.52.04.21.31.1-1.21.2-1.2-1.11.8-1.71.61.6-1.6-1.21.22.0-1.81.31.2-1.41.2-1.2-1.41.1
Delay discounting total patch changes 24 sec0.40.50.70.80.7-0.80.8-0.8-0.60.8-0.80.70.8-0.8-0.70.70.6-0.70.60.7-0.70.7-0.7-0.70.7
Delay discounting total patch changes 6 sec0.10.10.20.40.0-0.40.4-0.4-0.20.4-0.30.40.4-0.4-0.30.40.3-0.40.40.3-0.40.3-0.4-0.40.4
Delay discounting time to switch 0 sec0.81.33.01.31.0-0.70.7-0.7-0.91.7-1.71.31.3-1.3-1.00.91.2-1.11.31.0-1.20.9-0.9-1.11.0
Delay discounting water rate 0 sec0.91.53.3-1.4-1.10.8-0.80.81.0-1.81.8-1.4-1.31.31.1-1.0-1.51.3-1.4-1.01.2-1.01.01.1-1.1
Delay discounting water rate 12 sec0.30.40.60.30.6-0.80.8-0.8-0.70.2-0.30.60.6-0.6-0.60.70.5-0.60.40.7-0.70.7-0.7-0.70.7
Delay discounting water rate 18 sec0.81.12.1-1.1-0.90.8-0.80.80.8-1.41.4-1.2-1.21.21.0-0.8-1.11.1-1.0-0.91.0-0.80.91.0-0.6
Delay discounting water rate 24 sec0.00.00.30.10.0-0.10.1-0.1-0.10.20.10.0-0.00.0-0.00.20.5-0.40.10.0-0.10.2-0.2-0.10.1
Delay discounting water rate 6 sec0.10.10.20.20.4-0.50.5-0.5-0.4-0.00.20.00.0-0.0-0.30.40.4-0.40.20.4-0.20.5-0.4-0.30.4
Locomotor activity2.03.25.9-1.8-1.51.6-1.61.61.7-2.01.8-1.8-1.81.81.7-1.7-2.42.3-1.9-1.61.8-1.71.71.7-1.8
Locomotor testing distance4.98.111.1-2.9-2.62.6-2.62.62.7-3.23.0-2.8-2.82.82.8-2.7-3.33.2-3.0-2.62.8-2.72.72.8-2.8
Locomotor testing rearing0.10.20.6-0.3-0.40.3-0.30.30.5-0.50.4-0.5-0.50.50.3-0.3-0.80.6-0.3-0.30.4-0.30.30.4-0.4
Light reinforcement 10.91.73.5-1.0-1.91.5-1.51.51.6-0.81.2-1.3-1.41.41.1-1.3-0.40.6-0.8-1.51.3-1.31.31.4-1.2
Light reinforcement 20.91.21.8-0.9-1.31.2-1.21.21.1-0.91.1-1.2-1.31.31.0-1.1-0.30.6-0.8-1.31.1-1.11.11.2-1.1
Reaction time number correct3.14.55.52.12.0-2.02.0-2.0-2.12.3-2.32.22.3-2.3-2.22.11.8-1.92.12.0-2.22.0-2.1-2.22.2
Reaction time mean minus median5.06.58.3-2.6-2.42.5-2.52.52.4-2.92.9-2.6-2.72.72.6-2.5-2.42.4-2.5-2.52.6-2.52.52.6-2.6
Reaction time mean minus median AUC8.310.611.4-3.2-3.33.4-3.43.43.3-3.23.3-3.3-3.43.43.3-3.2-2.83.0-3.0-3.33.3-3.23.23.3-3.4
Reaction time num false alarms0.10.20.50.50.4-0.50.5-0.5-0.50.2-0.20.30.3-0.2-0.60.50.4-0.40.20.4-0.40.5-0.5-0.40.7
Reaction time num false alarms AUC0.30.50.90.80.6-0.80.8-0.8-0.70.6-0.50.50.5-0.5-0.90.80.6-0.60.60.7-0.60.8-0.8-0.71.0
Reaction time trials correct on left3.14.55.52.12.0-2.02.0-2.0-2.12.3-2.32.22.3-2.3-2.22.11.8-1.92.12.0-2.22.0-2.1-2.22.2
Reaction time trials on left2.84.04.81.91.9-1.91.9-1.9-1.92.2-2.22.12.2-2.2-2.11.91.7-1.82.01.9-2.11.9-1.9-2.02.0
Reaction time mean3.75.08.1-2.4-2.12.1-2.12.12.0-2.82.9-2.3-2.52.52.4-2.1-2.02.0-2.2-2.12.3-2.12.12.2-2.1
Reaction time mean AUC4.86.310.0-2.6-2.42.4-2.42.42.3-3.13.2-2.7-2.82.82.6-2.3-2.22.3-2.4-2.42.5-2.32.32.5-2.3
Median of all reaction times2.22.95.2-1.8-1.61.6-1.61.61.5-2.22.3-1.8-1.91.91.9-1.5-1.51.5-1.6-1.61.7-1.51.61.7-1.6
Reaction time omissions7.810.512.9-3.2-3.03.1-3.13.13.1-3.63.5-3.3-3.33.33.2-3.2-3.33.3-3.3-3.13.3-3.23.23.2-3.3
Reaction time false alarm rate0.10.10.4-0.2-0.40.2-0.20.20.3-0.50.5-0.5-0.60.60.2-0.3-0.30.4-0.4-0.40.4-0.20.30.4-0.1
Reaction time premature initiation rate1.92.53.41.41.8-1.81.8-1.8-1.61.2-1.21.51.6-1.6-1.51.61.8-1.81.41.8-1.61.6-1.6-1.61.3
Reaction time premature initiations4.05.76.52.22.5-2.62.6-2.6-2.42.1-2.22.42.5-2.5-2.32.42.4-2.42.22.5-2.42.3-2.3-2.42.2
Std. dev. reaction times5.17.012.9-2.8-2.22.3-2.32.32.3-3.53.6-2.9-3.03.02.7-2.4-2.42.4-2.6-2.42.7-2.32.42.6-2.5
Reaction time trials completed2.84.04.81.91.9-1.91.9-1.9-1.92.2-2.22.12.2-2.2-2.11.91.7-1.82.01.9-2.11.9-1.9-2.02.0
Reaction time trials AUC2.63.84.41.91.9-1.91.9-1.9-1.92.1-2.12.12.1-2.1-2.01.91.6-1.71.91.9-2.01.9-1.9-2.02.0
Social response proportion0.60.61.4-0.6-1.00.7-0.70.70.8-0.91.2-1.0-1.01.10.6-0.6-0.60.6-0.5-0.90.8-0.50.60.8-0.4
Social responses0.00.00.20.4-0.1-0.10.1-0.1-0.10.3-0.0-0.1-0.20.2-0.20.20.2-0.20.5-0.0-0.10.3-0.3-0.10.3
Social time1.11.42.3-0.9-1.51.4-1.41.41.4-0.70.9-1.2-1.21.21.1-1.2-0.81.0-0.9-1.41.2-1.21.21.3-1.3
Conditioned locomotion0.10.21.40.30.5-0.20.2-0.2-0.40.3-0.00.10.1-0.1-0.30.31.2-1.00.30.2-0.20.3-0.3-0.20.3
Cocaine response after cond. corrected2.32.67.4-1.7-1.71.5-1.51.51.6-1.51.2-1.3-1.21.21.6-1.6-2.72.4-1.7-1.51.5-1.61.61.4-1.6
Cocaine response after cond. not corrected2.52.76.8-1.6-1.61.6-1.61.61.6-1.61.3-1.5-1.51.41.6-1.6-2.62.3-1.6-1.51.5-1.61.61.5-1.6
Cocaine response before conditioning1.01.21.71.21.2-1.01.0-1.0-1.11.2-1.00.90.8-0.8-1.11.11.3-1.21.21.1-1.01.1-1.1-1.01.1
Saline control response0.60.93.20.90.8-0.90.9-0.9-0.90.7-0.40.60.6-0.6-0.90.91.8-1.50.90.8-0.80.9-0.9-0.80.9
Condit. Reinf. active minus inactive responses0.10.20.5-0.4-0.40.3-0.30.30.4-0.60.7-0.6-0.50.50.4-0.30.2-0.1-0.4-0.40.5-0.30.30.4-0.4
Condit. Reinf. active-inactive response ratio1.01.01.3-1.1-1.11.0-1.01.01.1-1.01.0-0.9-0.90.91.1-1.1-0.80.8-1.1-1.01.0-1.11.11.0-1.1
Condit. Reinf. active responses0.10.10.30.30.2-0.30.3-0.3-0.3-0.00.2-0.1-0.00.1-0.30.40.6-0.50.30.2-0.20.4-0.4-0.20.3
Condit. Reinf. inactive responses0.81.01.41.10.9-1.01.0-1.0-1.10.9-0.70.70.7-0.7-1.11.11.0-1.01.11.0-1.01.2-1.1-1.01.1
Condit. Reinf. lever presses2.33.15.1-1.8-1.61.7-1.71.71.6-2.12.3-2.0-2.02.01.8-1.7-1.11.3-1.8-1.81.9-1.61.71.8-1.8
Condit. Reinf. lever reinforcers received0.10.10.40.20.2-0.20.2-0.2-0.3-0.10.3-0.2-0.20.2-0.20.30.6-0.50.20.1-0.10.3-0.3-0.10.2
Pavlov. Cond. lever latency1.11.62.21.31.1-1.21.2-1.2-1.11.4-1.51.41.4-1.4-1.31.21.0-1.11.21.2-1.31.2-1.2-1.31.3
Pavlov. Cond. magazine entry latency1.72.02.91.31.7-1.51.5-1.5-1.61.1-0.91.21.1-1.1-1.41.51.7-1.71.31.5-1.31.5-1.5-1.41.4
Pavlov. Cond. change in total contacts0.40.50.8-0.8-0.60.7-0.70.70.6-0.90.9-0.8-0.80.80.7-0.7-0.60.6-0.8-0.70.8-0.70.70.7-0.7
Pavlov. Cond. index score0.10.10.5-0.30.00.2-0.20.20.0-0.60.7-0.5-0.50.50.2-0.10.4-0.3-0.3-0.20.3-0.10.10.3-0.2
Pavlov. Cond. latency score0.10.10.6-0.30.00.2-0.20.20.0-0.60.8-0.5-0.50.50.3-0.20.4-0.3-0.3-0.20.3-0.10.20.3-0.3
Pavlov. Cond. lever contacts0.81.11.7-1.1-1.01.0-1.01.01.0-1.21.3-1.2-1.21.21.1-1.0-0.60.8-1.1-1.11.1-1.01.01.1-1.1
Pavlov. Cond. magazine entry number0.30.41.3-0.5-0.80.7-0.70.70.8-0.30.2-0.5-0.40.40.6-0.6-1.11.0-0.5-0.60.5-0.60.60.6-0.5
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.3-0.60.5-0.50.50.6-0.30.4-0.5-0.50.50.4-0.4-0.20.4-0.3-0.50.4-0.40.40.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.40.00.2-0.20.20.1-0.60.7-0.5-0.50.50.3-0.20.3-0.2-0.3-0.20.3-0.20.20.3-0.3
Pavlov. Cond. response bias0.30.40.9-0.7-0.50.6-0.60.60.5-0.81.0-0.8-0.80.90.7-0.6-0.00.2-0.6-0.60.7-0.60.60.7-0.7
Conditioned reinforcement - actives0.10.10.8-0.4-0.0-0.10.1-0.10.1-0.90.7-0.3-0.30.30.2-0.1-0.50.4-0.50.00.2-0.10.10.2-0.2
Conditioned reinforcement - inactives1.51.72.2-1.0-1.41.5-1.51.51.4-0.80.9-1.3-1.31.31.2-1.4-1.11.2-1.0-1.41.3-1.41.41.4-1.4
Conditioned locomotion0.10.10.30.50.4-0.40.4-0.4-0.20.5-0.50.10.2-0.2-0.30.20.3-0.20.40.4-0.20.3-0.3-0.20.1
Intermittent access intake day 1-15 change0.10.10.20.20.0-0.00.0-0.0-0.10.4-0.40.40.4-0.4-0.40.10.1-0.10.20.1-0.30.1-0.1-0.20.3
Intermittent access intake escalation0.00.00.1-0.00.1-0.00.0-0.0-0.1-0.1-0.10.30.3-0.3-0.30.0-0.10.0-0.10.1-0.2-0.0-0.0-0.20.3
Intermittent access intake escalation 20.10.10.40.10.1-0.10.1-0.1-0.10.3-0.50.50.6-0.6-0.30.10.1-0.10.10.2-0.30.0-0.1-0.30.1
Intermitt. access day 1 inactive lever presses2.02.23.7-1.6-1.21.4-1.41.41.3-1.91.8-1.5-1.61.61.4-1.4-1.51.5-1.6-1.41.5-1.41.41.4-1.1
Intermitt. access day 15 inactive lever presses1.61.83.4-1.4-1.11.3-1.31.31.1-1.81.7-1.3-1.41.41.3-1.2-1.51.4-1.4-1.21.3-1.21.31.3-1.0
Intermitt. access escalation Index0.00.00.20.3-0.2-0.00.0-0.0-0.00.4-0.2-0.1-0.10.1-0.10.20.3-0.20.3-0.2-0.10.2-0.2-0.00.0
Intermittent access day 1 total infusions1.01.22.5-1.2-0.90.8-0.80.80.9-1.61.4-1.0-1.01.01.1-1.0-1.21.2-1.2-0.91.1-1.11.11.0-0.9
Intermittent access day 15 total infusions1.01.13.4-1.3-0.90.8-0.80.80.9-1.81.5-0.9-0.90.91.0-1.0-1.31.2-1.4-0.81.0-1.11.00.9-0.8
Intermittent access terminal intake (last 3 days)1.21.44.3-1.4-0.80.8-0.80.80.8-2.11.8-1.0-1.11.11.0-1.0-1.41.3-1.5-0.81.1-1.11.11.0-0.8
Intermittent access total infusions0.70.82.6-1.0-0.60.5-0.50.50.7-1.61.4-0.9-0.90.90.7-0.8-1.00.9-1.1-0.60.9-0.80.80.8-0.6
Intermittent access day 1 locomotion1.41.54.2-1.4-0.80.7-0.70.71.0-2.01.8-1.2-1.11.21.1-1.0-1.51.4-1.5-0.81.2-1.11.11.1-0.9
Intermittent access day 15 total locomotion1.31.33.2-1.4-0.80.9-0.90.90.9-1.81.5-1.1-1.11.11.1-1.1-1.61.5-1.4-0.81.1-1.11.11.1-0.8
Intermittent access total locomotion0.91.03.2-1.2-0.60.6-0.60.60.7-1.81.6-1.0-1.01.00.7-0.8-1.31.2-1.2-0.61.0-0.80.90.9-0.6
Intermittent access standard deviation0.20.20.70.30.2-0.20.2-0.2-0.10.6-0.80.80.8-0.8-0.40.10.3-0.20.30.3-0.50.1-0.1-0.40.3
Cocaine induced anxiety0.20.20.5-0.10.5-0.70.7-0.7-0.6-0.60.30.50.6-0.6-0.30.4-0.2-0.1-0.10.6-0.40.3-0.3-0.50.6
Post-drug Anxiety0.60.61.5-0.9-0.80.6-0.60.60.7-1.21.1-0.7-0.70.70.8-0.7-1.00.9-0.9-0.70.8-0.80.80.7-0.6
Baseline Anxiety0.70.81.3-0.3-0.91.1-1.11.11.10.10.2-1.1-1.11.10.8-0.9-0.30.6-0.3-1.00.9-0.80.81.0-1.0
Lifetime Intake0.60.72.7-1.0-0.50.5-0.50.50.6-1.61.5-0.9-0.90.90.7-0.7-0.90.8-1.1-0.50.8-0.70.70.7-0.5
Incentive Sensitization - Responses0.30.30.7-0.7-0.40.4-0.40.40.5-0.80.7-0.4-0.40.40.6-0.5-0.80.7-0.7-0.40.5-0.60.60.5-0.4
Incentive Sensitization - Breakpoint0.50.51.0-0.8-0.60.5-0.50.50.6-1.00.9-0.5-0.50.50.7-0.7-0.90.8-0.8-0.60.6-0.70.70.6-0.6
Progressive ratio test 1 active lever presses0.40.50.8-0.6-0.60.5-0.50.50.7-0.80.7-0.7-0.70.80.7-0.7-0.90.8-0.6-0.60.7-0.70.70.7-0.5
Progressive ratio test 1 breakpoint0.60.61.1-0.7-0.70.6-0.60.60.7-1.00.9-0.9-0.90.90.8-0.7-1.01.0-0.8-0.70.8-0.70.80.8-0.6
Progressive ratio test 1 inactive lever presses2.93.13.9-1.6-1.61.8-1.81.81.7-2.01.9-1.9-2.02.01.7-1.7-1.71.7-1.7-1.71.8-1.71.71.8-1.5
Progressive ratio test 2 active lever presses1.71.82.7-1.4-1.31.1-1.11.11.4-1.61.4-1.1-1.11.01.4-1.4-1.61.6-1.5-1.21.3-1.41.41.3-1.3
Progressive ratio test 2 breakpoint1.51.72.3-1.4-1.31.2-1.21.21.4-1.51.3-1.1-1.11.01.4-1.4-1.51.5-1.4-1.21.3-1.41.41.2-1.3
Progressive ratio test 2 inactive lever presses2.42.86.2-1.9-1.31.3-1.31.31.4-2.52.2-1.5-1.51.51.8-1.5-2.01.8-1.9-1.31.6-1.61.61.5-1.6
Total sessions with >9 infusions2.62.83.4-1.5-1.61.6-1.61.61.7-1.81.8-1.8-1.81.81.6-1.7-1.71.7-1.6-1.71.7-1.71.71.7-1.4
Short access day 1 total inactive lever presses0.10.10.4-0.1-0.30.5-0.50.50.2-0.20.5-0.5-0.60.70.2-0.2-0.00.0-0.1-0.40.4-0.20.20.4-0.2
Short access day 10 total inactive lever presses0.91.01.9-1.2-0.81.1-1.11.10.7-1.41.3-0.9-1.01.01.1-0.9-0.80.8-1.1-0.90.9-0.90.90.9-0.8
Short access day 1 total infusions0.50.50.7-0.6-0.60.7-0.70.70.7-0.80.9-0.8-0.80.80.6-0.7-0.60.7-0.7-0.70.7-0.60.70.7-0.5
Short access day 10 total infusions0.20.21.1-0.20.5-0.50.5-0.5-0.4-1.10.9-0.2-0.20.3-0.20.3-0.20.0-0.30.40.00.3-0.2-0.10.4
Short access total infusions0.40.41.6-0.6-0.30.3-0.30.30.4-1.31.2-0.8-0.80.90.5-0.4-0.60.5-0.7-0.40.6-0.40.40.6-0.2
Short access day 1 locomotion0.00.00.10.10.2-0.00.0-0.0-0.0-0.10.1-0.2-0.20.2-0.00.00.1-0.00.00.10.10.1-0.00.10.1
Short access day 10 total locomotion0.30.31.6-0.7-0.00.1-0.10.10.1-1.31.1-0.5-0.50.50.3-0.2-0.80.6-0.7-0.10.4-0.30.30.3-0.0
Short access total locomotion0.80.82.3-0.9-0.40.6-0.60.60.6-1.51.4-1.1-1.11.10.7-0.7-1.00.9-1.0-0.60.9-0.70.70.8-0.6
Compulsive drug intake1.91.82.51.11.3-1.41.4-1.4-1.51.2-1.11.31.2-1.2-1.21.51.4-1.51.31.3-1.41.5-1.5-1.41.6
One hour access (0.3 mA shock)0.00.00.1-0.3-0.1-0.10.1-0.10.1-0.40.30.00.0-0.00.2-0.1-0.10.1-0.2-0.00.1-0.10.10.0-0.0
One hour access (shock baseline)1.01.11.5-1.1-0.91.0-1.01.01.1-1.21.0-0.9-0.90.91.1-1.2-1.11.2-1.1-0.91.1-1.21.21.1-1.1
Number of responses in last shaping day0.30.30.7-0.3-0.70.6-0.60.60.80.0-0.1-0.4-0.40.30.5-0.7-0.20.4-0.3-0.60.5-0.60.60.6-0.8
Context. condit. distance diff. score4.65.67.52.32.2-2.32.3-2.3-2.32.6-2.72.62.6-2.7-2.32.22.1-2.22.32.4-2.42.2-2.2-2.42.4
Locomotion velocity, session 10.10.10.2-0.3-0.40.2-0.20.20.3-0.10.2-0.2-0.20.20.3-0.20.2-0.1-0.3-0.20.2-0.20.20.2-0.3
Locomotion distance, session 10.60.81.3-0.8-0.80.8-0.80.80.8-0.91.0-1.1-1.11.10.8-0.8-0.80.8-0.8-0.90.9-0.70.80.9-0.8
Locomotion velocity, session 20.70.81.21.01.0-1.01.0-1.0-1.10.9-0.70.70.7-0.7-0.91.00.8-0.90.90.9-0.91.0-1.0-0.90.9
Locomotion distance, session 21.01.42.7-1.0-1.11.2-1.21.21.1-1.21.5-1.6-1.61.61.1-1.1-0.50.7-1.0-1.31.3-1.01.01.3-1.0
Locomotion velocity, session 30.70.81.61.10.8-0.80.8-0.8-0.81.0-0.80.80.8-0.7-1.00.91.3-1.21.10.8-0.90.9-0.9-0.81.0
Locomotion distance, session 31.61.82.21.31.1-1.31.3-1.3-1.21.4-1.51.51.5-1.5-1.31.31.2-1.21.31.3-1.41.3-1.3-1.41.3
Stereotopy head waving bouts, day 31.01.21.51.21.1-1.01.0-1.0-1.01.2-1.11.01.0-1.0-1.11.11.2-1.21.21.0-1.11.1-1.1-1.01.2
Stereotopy head waving duration, day 31.51.82.51.51.3-1.31.3-1.3-1.31.3-1.11.21.1-1.1-1.41.41.6-1.51.51.3-1.31.4-1.4-1.31.4
Locomotion velocity, session 70.10.10.2-0.2-0.30.4-0.40.40.3-0.10.1-0.3-0.30.30.3-0.4-0.00.2-0.2-0.40.3-0.40.40.4-0.3
Locomotion distance, session 70.20.20.4-0.5-0.50.6-0.60.60.5-0.20.1-0.3-0.20.20.5-0.6-0.30.3-0.5-0.50.4-0.60.60.5-0.5
Stereotopy head waving bouts, day 70.10.20.30.50.5-0.40.4-0.4-0.50.2-0.20.30.3-0.3-0.40.50.4-0.40.40.4-0.40.5-0.5-0.40.4
Stereotopy head waving duration, day 70.10.10.40.30.3-0.20.2-0.2-0.3-0.00.2-0.0-0.10.1-0.30.30.6-0.50.30.2-0.10.3-0.3-0.10.3
Locomotion velocity, session 80.10.21.8-0.2-0.30.2-0.20.20.20.00.3-0.1-0.10.10.2-0.21.4-0.9-0.2-0.20.2-0.20.20.2-0.2
Locomotion distance, session 80.00.10.60.20.1-0.00.0-0.0-0.20.3-0.10.0-0.00.0-0.20.10.8-0.60.20.1-0.10.2-0.2-0.10.3
Degree of sensitization distance3.63.64.0-2.0-1.92.0-2.02.01.9-1.71.6-1.8-1.81.72.0-2.0-1.92.0-2.0-1.91.9-2.02.01.9-1.9
Degree of sensitization stereotypy0.00.10.2-0.2-0.10.1-0.10.10.1-0.50.5-0.3-0.30.30.2-0.1-0.20.1-0.3-0.20.2-0.10.10.2-0.2
Condit. Reinf. active minus inactive responses4.85.37.5-2.3-2.22.2-2.22.22.2-2.72.7-2.5-2.52.52.2-2.2-2.12.1-2.3-2.32.4-2.22.22.3-2.2
Condit. Reinf. active-inactive response ratio4.34.67.1-2.1-2.02.0-2.02.02.0-2.62.7-2.4-2.42.52.0-2.0-1.81.9-2.1-2.12.2-1.92.02.2-2.0
Condit. Reinf. active responses6.17.410.1-2.7-2.72.6-2.62.62.8-3.13.2-2.9-2.92.92.6-2.6-2.22.4-2.7-2.72.8-2.62.62.8-2.6
Condit. Reinf. inactive responses2.22.63.2-1.6-1.81.6-1.61.61.8-1.51.4-1.5-1.41.41.6-1.7-1.61.6-1.6-1.61.6-1.71.71.6-1.6
Incentive salience index mean3.74.56.8-2.1-2.02.0-2.02.02.0-2.62.6-2.3-2.32.32.1-2.0-1.61.7-2.1-2.12.2-2.02.02.1-2.0
Condit. Reinf. lever presses1.31.72.8-1.3-1.31.3-1.31.31.4-1.51.7-1.4-1.41.41.3-1.3-0.10.5-1.3-1.41.4-1.31.31.4-1.3
Time in familiar zone, hab. session 12.62.43.41.51.7-1.41.4-1.4-1.61.8-1.91.71.7-1.7-1.41.41.8-1.71.51.5-1.61.3-1.4-1.51.4
Time in novel zone, hab. session 10.10.10.3-0.3-0.40.1-0.10.10.2-0.60.6-0.4-0.40.40.2-0.1-0.60.4-0.3-0.20.2-0.10.10.2-0.2
Total zone transitions, hab. session 11.62.23.2-1.4-1.31.6-1.61.61.3-1.61.8-1.7-1.71.71.5-1.5-0.30.7-1.4-1.61.6-1.41.51.6-1.4
Total locomotion distance, hab. session 12.53.64.9-1.8-1.82.0-2.02.01.7-2.02.1-2.1-2.22.21.9-1.9-1.41.5-1.7-2.02.0-1.81.82.0-1.8
Locomotion velocity, hab. session 14.36.27.9-2.3-2.42.6-2.62.62.3-2.62.7-2.7-2.82.82.4-2.4-2.02.1-2.3-2.62.6-2.42.42.6-2.4
Time in familiar zone, hab. session 27.37.68.82.82.8-2.72.7-2.7-2.92.9-3.02.92.9-2.9-2.82.72.3-2.42.72.8-2.82.7-2.7-2.82.8
Time in novel zone, hab. session 23.43.54.5-1.8-1.81.8-1.81.82.0-2.02.1-2.1-2.02.11.8-1.8-1.41.5-1.8-1.91.9-1.81.81.9-1.9
Total zone transitions, hab. session 20.81.01.6-1.0-1.11.0-1.01.00.9-1.11.3-1.2-1.21.21.0-1.0-0.30.5-1.0-1.11.1-1.01.01.1-1.0
Total locomotion distance, hab. session 22.83.74.0-1.9-2.02.0-2.02.01.8-1.81.8-1.9-1.91.92.0-1.9-1.71.8-1.9-2.02.0-1.91.92.0-1.9
Locomotion velocity, hab. session 23.14.24.6-2.1-2.12.1-2.12.11.9-2.02.0-2.1-2.12.12.1-2.1-1.81.9-2.1-2.12.1-2.12.12.1-2.1
Novel to familiar place preference ratio0.10.10.30.00.00.0-0.00.00.1-0.40.5-0.4-0.50.50.00.0-0.50.30.0-0.10.20.1-0.00.2-0.0
Novelty place preference0.10.10.20.20.2-0.10.1-0.1-0.1-0.30.5-0.3-0.40.4-0.20.2-0.50.20.20.00.10.3-0.20.00.1
Time in novel zone, NPP test0.10.10.20.40.3-0.30.3-0.3-0.2-0.20.3-0.2-0.20.3-0.30.4-0.30.10.40.2-0.10.4-0.4-0.10.3
Total zone transitions, NPP test2.02.84.3-1.7-1.81.6-1.61.61.6-1.92.1-1.9-1.91.91.7-1.6-0.91.1-1.7-1.71.8-1.61.61.8-1.7
Total locomotion distance, NPP test1.92.63.9-1.5-1.61.5-1.51.51.4-1.82.0-1.9-1.92.01.5-1.5-1.31.4-1.5-1.61.7-1.41.51.7-1.5
Locomotion velocity, NPP test2.53.54.8-1.8-1.91.8-1.81.81.7-2.02.2-2.1-2.22.21.8-1.7-1.61.7-1.8-1.91.9-1.71.71.9-1.8
Pavlov. Cond. lever latency0.10.10.40.40.2-0.20.2-0.2-0.30.7-0.60.30.3-0.4-0.30.30.2-0.20.40.3-0.30.3-0.3-0.30.3
Pavlov. Cond. magazine entry latency0.10.10.20.30.5-0.40.4-0.4-0.30.2-0.20.30.3-0.3-0.40.4-0.2-0.00.40.4-0.40.4-0.4-0.40.4
Pavlov. Cond. change in total contacts1.41.51.9-1.3-1.11.2-1.21.21.2-1.21.0-1.0-0.90.91.3-1.3-1.41.4-1.3-1.21.2-1.31.31.1-1.3
Pavlov. Cond. index score0.20.30.40.40.6-0.60.6-0.6-0.50.3-0.30.50.5-0.5-0.50.50.5-0.50.50.6-0.50.5-0.5-0.50.5
Pavlov. Cond. latency score0.10.10.20.30.4-0.40.4-0.4-0.30.1-0.20.40.4-0.4-0.30.40.1-0.20.30.4-0.40.4-0.4-0.40.3
Pavlov. Cond. lever contacts0.20.20.6-0.5-0.30.3-0.30.30.5-0.80.8-0.5-0.50.50.4-0.4-0.20.2-0.4-0.40.4-0.30.40.4-0.4
Pavlov. Cond. magazine entry number0.91.11.4-1.1-1.21.2-1.21.21.1-0.80.8-0.9-0.90.91.1-1.2-0.81.0-1.1-1.11.1-1.21.21.1-1.1
Pavlov. Cond. intertrial magazine entries5.97.17.7-2.6-2.72.8-2.82.82.6-2.62.6-2.7-2.72.72.7-2.7-2.12.4-2.7-2.82.7-2.72.72.8-2.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.50.7-0.60.6-0.6-0.50.4-0.40.60.6-0.6-0.60.60.6-0.60.50.6-0.60.6-0.6-0.60.6
Pavlov. Cond. response bias0.10.10.30.40.5-0.50.5-0.5-0.30.00.00.20.2-0.2-0.40.40.5-0.50.40.4-0.30.5-0.4-0.30.4
Bone: apparent density12.019.923.84.44.2-4.44.4-4.4-4.44.7-4.94.74.8-4.8-4.54.43.5-3.94.44.5-4.64.4-4.4-4.64.5
Bone surface6.210.911.83.42.9-3.43.4-3.4-3.33.3-3.33.33.3-3.3-3.43.42.7-2.93.43.4-3.43.4-3.4-3.43.4
Bone volume9.916.817.64.23.8-4.24.2-4.2-4.14.2-4.24.14.1-4.1-4.24.23.5-3.84.24.2-4.24.2-4.2-4.24.2
Bone: connectivity density6.19.513.13.02.9-3.13.1-3.1-3.13.3-3.63.43.4-3.4-3.13.01.9-2.33.03.2-3.23.0-3.0-3.23.1
Bone: cortical apparent density0.10.10.6-0.00.20.0-0.00.0-0.10.5-0.60.60.6-0.60.0-0.10.7-0.6-0.00.1-0.2-0.20.1-0.2-0.0
Bone: cortical area4.77.111.42.72.4-2.72.7-2.7-2.72.3-2.02.42.3-2.3-2.72.83.4-3.22.72.6-2.62.8-2.8-2.62.7
Bone: cortical porosity0.80.81.6-0.7-0.80.8-0.80.80.7-1.11.2-1.2-1.21.30.7-0.7-1.11.0-0.7-0.90.9-0.70.70.9-0.8
Bone: cortical porosity0.10.10.6-0.1-0.30.1-0.10.10.1-0.50.6-0.6-0.60.70.1-0.0-0.80.6-0.1-0.20.30.00.00.3-0.1
Bone: cortical thickness3.35.48.62.42.1-2.32.3-2.3-2.22.1-1.92.12.1-2.0-2.42.42.9-2.82.42.3-2.32.4-2.4-2.32.4
Bone: cortical thickness3.13.64.21.91.6-1.91.9-1.9-1.81.9-1.81.91.9-1.9-1.91.92.0-2.01.91.9-1.91.9-1.9-1.91.9
Bone: cortical tissue density0.10.10.3-0.10.20.1-0.10.1-0.00.5-0.60.50.5-0.60.1-0.20.6-0.4-0.10.0-0.2-0.20.2-0.1-0.1
Bone: elastic displacement0.30.40.70.60.8-0.60.6-0.6-0.80.5-0.60.50.5-0.5-0.60.6-0.1-0.10.60.6-0.60.6-0.6-0.60.6
Bone: elastic work1.82.33.21.71.8-1.71.7-1.7-1.81.2-1.01.21.1-1.1-1.71.71.0-1.21.71.6-1.51.8-1.7-1.51.7
Bone: endosteal estimation0.40.81.21.00.9-1.01.0-1.0-1.10.6-0.50.70.7-0.6-1.01.10.6-0.71.01.0-0.91.1-1.1-0.91.0
Bone: endosteal perimeter1.73.54.21.91.9-2.02.0-2.0-2.01.6-1.41.71.6-1.6-1.92.02.0-2.01.91.9-1.82.0-2.0-1.81.9
Bone: final force4.57.48.92.92.5-2.82.8-2.8-2.72.3-2.12.32.4-2.3-2.92.92.9-3.02.92.7-2.73.0-2.9-2.72.9
Bone: final moment4.87.99.63.02.7-3.03.0-3.0-2.82.5-2.22.52.5-2.4-3.03.02.7-2.93.02.9-2.83.1-3.1-2.83.0
Bone: marrow area0.40.91.31.00.9-1.11.1-1.1-1.10.7-0.60.70.7-0.7-1.11.10.6-0.71.01.0-0.91.1-1.1-0.91.1
Bone: maximum diameter4.88.811.92.92.8-3.03.0-3.0-3.02.8-2.62.82.8-2.8-3.03.03.5-3.32.93.0-2.93.0-3.0-3.03.0
Bone: maximum force2.44.25.42.21.9-2.22.2-2.2-2.11.6-1.41.71.6-1.6-2.22.32.0-2.12.22.1-2.02.3-2.3-2.02.2
Bone: maximum moment2.44.25.52.22.0-2.22.2-2.2-2.11.7-1.51.71.7-1.6-2.22.31.7-2.02.22.1-2.02.3-2.3-2.02.3
Bone: minimum diameter1.12.03.01.51.3-1.51.5-1.5-1.51.0-0.71.01.0-1.0-1.51.61.7-1.71.51.4-1.31.6-1.6-1.31.5
Bone: periosteal estimation2.04.15.02.11.9-2.22.2-2.2-2.11.6-1.41.71.7-1.6-2.12.22.2-2.22.12.1-2.02.2-2.2-2.02.2
Bone: periosteal perimeter4.47.39.42.82.7-2.82.8-2.8-2.82.4-2.22.42.4-2.4-2.82.83.1-3.02.82.7-2.62.8-2.8-2.72.8
Bone: post-yield work1.21.62.3-1.2-1.51.2-1.21.21.3-1.41.4-1.4-1.31.31.2-1.2-1.11.1-1.2-1.31.3-1.21.21.3-1.2
Bone: stiffness0.81.22.11.11.0-1.21.2-1.2-1.10.8-0.60.80.8-0.8-1.21.21.4-1.51.11.1-1.11.3-1.2-1.11.2
Bone: tissue strength0.00.00.10.0-0.00.0-0.00.00.0-0.10.2-0.2-0.20.20.00.0-0.30.20.0-0.10.10.0-0.00.1-0.0
Bone: trabecular number14.622.727.54.84.5-4.74.7-4.7-4.75.1-5.25.05.1-5.1-4.84.73.8-4.14.84.8-4.94.6-4.7-4.94.8
Bone: trabecular spacing7.29.311.3-3.1-3.03.1-3.13.13.1-3.23.4-3.2-3.23.23.1-3.1-2.02.4-3.1-3.13.2-3.03.13.2-3.1
Bone: trabecular thickness12.515.118.83.93.7-3.93.9-3.9-3.94.2-4.34.14.2-4.2-3.93.82.9-3.33.94.0-4.03.8-3.8-4.03.9
Bone: trabecular tissue density0.71.01.7-1.0-0.91.0-1.01.01.0-0.90.8-0.9-0.90.91.0-1.0-1.31.1-1.0-1.01.0-1.01.01.0-1.0
Breakpoint value in progressive ratio session0.10.10.40.1-0.50.3-0.30.30.40.3-0.1-0.7-0.60.60.2-0.20.00.10.1-0.50.4-0.10.20.4-0.6
Distance traveled before self-admin0.20.21.10.6-0.1-0.00.0-0.0-0.01.0-0.90.20.3-0.3-0.30.20.5-0.40.60.1-0.30.2-0.2-0.20.1
Distance traveled after self-admin0.40.40.6-0.6-0.70.8-0.80.80.6-0.60.4-0.5-0.50.50.5-0.7-0.60.7-0.7-0.70.6-0.70.70.6-0.7
Delta time in closed arm before/after self-admin0.20.20.40.50.4-0.50.5-0.5-0.40.5-0.60.50.5-0.5-0.40.40.5-0.50.50.5-0.50.4-0.4-0.50.3
Delta time in open arm before/after self-admin0.30.30.60.40.7-0.40.4-0.4-0.70.6-0.40.40.4-0.3-0.70.70.5-0.60.50.5-0.50.7-0.7-0.50.7
Diff in mean of infusions in LGA sessions1.01.12.0-0.7-1.41.2-1.21.21.2-0.50.8-1.4-1.31.40.9-1.0-0.70.9-0.6-1.41.1-0.90.91.2-0.8
Extinction: sum of active levers before priming4.14.15.8-1.5-2.32.2-2.22.22.3-1.11.4-2.4-2.32.31.8-2.0-1.51.8-1.5-2.32.1-1.92.02.2-2.4
Active lever presses in extinction session 60.70.71.1-0.7-0.80.8-0.80.80.9-0.60.6-1.0-1.01.00.8-0.8-0.60.7-0.6-0.90.9-0.80.80.9-0.9
Delta distance traveled before/after self-admin0.10.10.4-0.50.00.3-0.30.30.1-0.60.5-0.2-0.30.30.3-0.3-0.40.4-0.5-0.20.3-0.30.30.2-0.3
Delta ambulatory time before/after self-admin0.10.10.5-0.50.20.0-0.00.0-0.1-0.70.50.0-0.10.10.1-0.1-0.40.3-0.40.00.1-0.10.10.0-0.1
Time in closed arm before self-admin1.82.02.81.11.5-1.61.6-1.6-1.70.9-0.71.41.3-1.3-1.41.71.2-1.41.21.5-1.51.6-1.6-1.51.7
Time in closed arm after self-admin0.10.10.3-0.20.2-0.40.4-0.4-0.4-0.60.40.40.3-0.3-0.20.3-0.1-0.0-0.10.3-0.30.2-0.2-0.30.3
Time in open arm before self-admin2.93.14.0-1.5-1.91.7-1.71.72.0-1.71.5-1.7-1.61.61.8-1.9-1.61.8-1.7-1.81.8-1.91.91.8-2.0
Time in open arm after self-admin0.20.20.60.50.5-0.30.3-0.3-0.40.8-0.80.30.4-0.4-0.50.40.5-0.50.50.4-0.40.4-0.4-0.30.4
Sum of active levers in priming session hrs 5-63.43.35.0-1.3-2.22.0-2.02.02.2-1.01.1-1.9-1.91.81.8-1.9-1.31.6-1.4-2.11.9-1.91.92.0-2.2
Time to tail flick, vehicle, before self-admin0.10.10.4-0.10.5-0.40.4-0.4-0.4-0.20.10.30.3-0.3-0.40.30.0-0.10.00.4-0.30.3-0.3-0.30.6
Time to tail flick, vehicle, after self-admin3.94.25.7-1.8-2.32.1-2.12.12.3-1.81.9-2.1-2.02.02.0-2.1-1.81.9-1.8-2.22.1-2.12.12.1-2.4
Time to tail flick, test, before self-admin4.44.37.3-2.2-1.91.8-1.81.81.9-2.72.7-2.0-2.12.12.1-1.9-2.22.1-2.2-1.92.0-1.91.92.0-1.9
Time to tail flick, test, after self-admin0.30.41.8-0.9-0.20.1-0.10.10.1-1.41.2-0.5-0.50.50.3-0.3-0.80.6-0.9-0.20.5-0.40.40.4-0.1
Delta time to tail flick, vehicle, before/after SA0.60.61.3-0.3-1.00.8-0.80.81.0-0.20.4-0.9-0.80.80.7-0.8-0.40.6-0.4-0.90.8-0.80.80.9-1.1
Delta time to tail flick, test, before/after SA1.31.21.61.01.1-1.01.0-1.0-1.11.1-1.31.21.3-1.3-1.11.01.0-1.01.01.1-1.10.9-1.0-1.11.2
Ambulatory time before self-admin0.10.10.40.3-0.40.3-0.30.30.30.6-0.6-0.1-0.00.0-0.0-0.20.2-0.00.2-0.30.1-0.20.10.2-0.2
Ambulatory time after self-admin0.10.10.50.30.2-0.00.0-0.0-0.30.6-0.70.40.4-0.4-0.40.20.4-0.30.30.2-0.30.1-0.2-0.30.1
Total heroin consumption0.00.00.20.1-0.1-0.10.1-0.1-0.00.20.1-0.5-0.40.5-0.30.20.1-0.10.2-0.10.10.3-0.20.1-0.1
Area under the delay curve0.30.31.3-0.7-0.40.3-0.30.30.4-1.10.9-0.3-0.30.30.5-0.5-0.80.7-0.7-0.40.4-0.50.50.4-0.5
Delay disc. indifference point, 0s delay0.10.10.6-0.3-0.1-0.10.1-0.10.0-0.80.8-0.5-0.40.50.1-0.0-0.60.4-0.4-0.10.3-0.00.10.2-0.0
Delay disc. indifference point, 16s delay2.62.74.9-1.8-1.71.5-1.51.51.7-2.21.9-1.3-1.21.21.7-1.7-1.61.6-1.8-1.61.5-1.71.71.5-1.7
Delay disc. indifference point, 2s delay0.20.20.40.20.4-0.70.7-0.7-0.5-0.10.10.20.2-0.2-0.50.6-0.0-0.20.30.5-0.30.5-0.5-0.40.6
Delay disc. indifference point, 24s delay0.10.10.2-0.3-0.40.4-0.40.40.4-0.40.20.10.1-0.10.4-0.4-0.40.4-0.3-0.30.2-0.50.40.2-0.5
Delay disc. indifference point, 4s delay1.01.11.60.81.3-1.21.2-1.2-1.20.6-0.71.11.0-1.0-1.11.10.7-0.80.81.2-1.01.1-1.1-1.11.1
Delay disc. indifference point, 8s delay0.30.31.2-0.7-0.20.3-0.30.30.3-1.10.9-0.5-0.40.50.5-0.4-0.70.6-0.7-0.30.5-0.40.40.4-0.5
Delay discount exponential model param0.20.20.80.50.3-0.20.2-0.2-0.30.9-0.70.20.2-0.2-0.30.30.7-0.50.50.2-0.30.4-0.4-0.20.3
Delay discount hyperbolic model param0.10.10.70.50.2-0.10.1-0.1-0.20.9-0.70.20.2-0.2-0.20.20.6-0.50.50.2-0.30.3-0.3-0.20.3
Fecal boli incidents, locomotor time 13.33.54.5-1.8-2.12.1-2.12.12.1-1.61.6-1.6-1.61.61.9-2.0-1.61.8-1.7-2.01.8-2.02.01.9-2.0
Change in fecal boli incidents, locomotor task2.01.93.11.31.5-1.41.4-1.4-1.41.3-1.51.71.7-1.8-1.21.30.9-1.11.21.5-1.41.2-1.2-1.41.3
Time >=10cm from walls, locomotor time 10.50.50.90.60.7-0.80.8-0.8-0.60.7-0.80.80.9-1.0-0.70.60.9-0.80.70.7-0.70.6-0.6-0.70.6
Bouts of movement, locomotor time 11.31.52.20.91.5-1.41.4-1.4-1.40.9-0.81.01.0-1.0-1.31.31.0-1.11.01.4-1.21.3-1.3-1.21.3
Total resting periods, locomotor time 12.32.53.31.41.8-1.71.7-1.7-1.71.5-1.41.41.4-1.4-1.61.71.4-1.51.51.7-1.61.7-1.7-1.61.7
Rest time, locomotor task time 11.51.73.01.41.3-1.11.1-1.1-1.21.7-1.61.21.1-1.1-1.31.31.4-1.41.41.2-1.31.3-1.3-1.31.2
Distance moved, locomotor task time 11.21.42.1-1.1-1.41.2-1.21.21.3-1.21.1-1.0-0.90.91.2-1.3-1.01.1-1.2-1.31.1-1.31.31.2-1.2
Vertical activity count, locomotor time 11.01.01.7-1.0-1.10.9-0.90.91.0-1.31.2-0.9-0.80.81.1-1.1-0.90.9-1.1-1.01.0-1.11.11.0-1.0
Time >=10cm from walls, locomotor time 20.60.61.40.51.2-0.90.9-0.9-1.00.5-0.40.60.5-0.5-0.70.90.9-0.90.60.9-0.70.9-0.8-0.70.9
Bouts of movement, locomotor time 21.21.32.50.71.5-1.61.6-1.6-1.30.2-0.30.80.9-0.8-1.21.30.6-0.80.81.4-1.01.3-1.2-1.11.4
Total resting periods, locomotor time 21.51.62.90.81.6-1.71.7-1.7-1.40.4-0.51.01.1-1.0-1.31.40.7-0.90.91.5-1.11.4-1.3-1.21.5
Rest time, locomotor task time 22.22.64.41.71.5-1.41.4-1.4-1.52.1-1.91.51.5-1.5-1.61.61.7-1.71.81.5-1.61.6-1.6-1.61.5
Distance moved, locomotor task time 20.40.50.6-0.6-0.70.7-0.70.70.7-0.60.7-0.7-0.60.60.7-0.7-0.60.6-0.8-0.70.7-0.70.70.7-0.6
Vertical activity count, locomotor time 20.10.10.20.30.2-0.10.1-0.1-0.10.4-0.40.20.3-0.3-0.10.10.5-0.40.20.2-0.20.1-0.1-0.10.1
Weight adjusted by age0.40.51.00.70.6-1.01.0-1.0-0.60.5-0.70.70.8-0.8-0.80.70.4-0.50.40.8-0.60.6-0.6-0.70.6
Seeking ratio, delayed vs. immediate footshock0.50.50.90.40.8-0.90.9-0.9-0.70.2-0.40.90.9-0.9-0.70.70.6-0.60.50.9-0.80.6-0.7-0.80.7
Locomotion in novel chamber0.20.20.9-0.7-0.00.3-0.30.30.2-1.00.7-0.3-0.30.30.3-0.3-0.90.7-0.8-0.20.4-0.40.40.3-0.3
Locomotion in novel chamber post-restriction0.00.00.10.20.20.0-0.00.0-0.30.4-0.3-0.00.0-0.0-0.10.2-0.0-0.00.20.1-0.10.2-0.2-0.10.2
Progressive ratio0.00.00.10.1-0.10.0-0.00.00.10.2-0.2-0.1-0.10.1-0.10.0-0.00.00.1-0.10.00.0-0.00.0-0.0
Food seeking constrained by brief footshock0.20.20.7-0.7-0.10.4-0.40.40.1-0.70.8-0.6-0.70.70.6-0.2-0.40.3-0.6-0.30.5-0.20.30.4-0.2
Seeking ratio, punishment vs. effort0.60.71.6-1.1-0.50.7-0.70.70.6-1.31.3-0.9-0.90.90.9-0.7-0.70.7-1.0-0.70.8-0.70.70.8-0.6
Run reversals in cocaine runway, females0.70.71.4-0.9-1.00.7-0.70.70.6-1.21.1-0.7-0.70.70.7-0.6-1.10.9-1.0-0.80.8-0.70.70.7-0.4
Run reversals in cocaine runway, males1.11.01.7-1.0-0.91.0-1.01.01.1-1.00.9-1.0-0.90.91.1-1.1-0.90.9-1.0-0.91.0-1.11.11.0-1.3
Latency to leave start box in cocaine runway0.10.10.60.2-0.20.3-0.30.30.30.6-0.80.50.5-0.50.1-0.30.2-0.00.2-0.1-0.1-0.30.2-0.1-0.3
Latency to leave start box in cocaine runway, F0.50.51.80.70.4-0.40.4-0.4-0.31.2-1.31.01.0-1.1-0.40.40.8-0.70.80.6-0.70.3-0.4-0.60.1
Latency to leave start box in cocaine runway, M0.80.81.1-0.8-1.01.1-1.11.11.0-0.70.6-0.6-0.70.70.8-1.0-0.90.9-0.9-1.00.8-1.01.00.8-0.8
Cd content in liver0.10.10.1-0.3-0.00.3-0.30.30.2-0.00.1-0.3-0.30.20.3-0.30.10.1-0.3-0.30.3-0.30.30.3-0.2
Co content in liver3.13.64.9-1.8-1.61.9-1.91.91.8-1.81.8-2.0-2.02.01.9-1.9-2.22.2-1.9-1.92.0-1.81.92.0-2.0
Cu content in liver0.20.30.4-0.6-0.50.5-0.50.50.5-0.60.6-0.5-0.50.50.5-0.60.00.2-0.6-0.50.5-0.60.60.5-0.5
Fe content in liver1.31.53.41.21.2-1.11.1-1.1-1.11.6-1.81.51.5-1.6-1.11.10.2-0.41.21.2-1.31.0-1.1-1.30.9
K content in liver0.00.00.10.00.0-0.10.1-0.1-0.1-0.30.4-0.2-0.30.3-0.10.10.0-0.00.0-0.00.00.2-0.10.00.2
Mg content in liver0.70.71.3-0.8-0.80.8-0.80.80.8-1.01.2-1.0-1.01.00.8-0.8-0.20.3-0.8-0.90.9-0.70.80.9-0.7
Mn content in liver0.00.10.30.10.1-0.10.1-0.1-0.10.4-0.60.40.4-0.4-0.10.00.1-0.00.10.1-0.20.0-0.0-0.20.1
Na content in liver0.80.81.20.90.8-0.90.9-0.9-0.90.8-0.60.80.8-0.8-0.91.01.1-1.10.90.9-0.91.0-1.0-0.90.9
Rb content in liver0.91.11.4-1.2-1.11.1-1.11.11.1-1.11.1-0.9-1.00.91.1-1.1-0.60.7-1.1-1.11.0-1.11.11.0-1.0
Se content in liver0.20.21.30.10.3-0.10.1-0.1-0.10.8-1.10.70.8-0.8-0.10.1-0.20.20.10.3-0.4-0.0-0.0-0.40.1
Sr content in liver0.80.70.80.90.9-0.90.9-0.9-0.80.8-0.80.80.8-0.8-0.90.90.7-0.80.90.9-0.90.9-0.9-0.90.9
Zn content in liver0.20.20.4-0.5-0.20.5-0.50.50.3-0.10.1-0.3-0.30.30.5-0.5-0.60.6-0.5-0.40.4-0.50.50.4-0.4