Hub : Genes

ENSRNOG00000050741

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000050741	0.32	0.14	7.5e-08	0.07	0.05	0.05	0.06	8.4e-08	2.8e-06	3.6e-06	4.4e-07
2	BLA	gene expression	ENSRNOG00000050741	0.08	0.07	4.3e-03	0.03	0.03	0.02	0.02	6.7e-03	1.5e-02	2.9e-02	1.9e-02
3	Brain	intron excision ratio	chr1:202078683:202086011	0.03	0.02	3.9e-03	0.02	0.03	0.01	0.03	5.9e-03	1.5e-03	2.5e-02	1.3e-03
4	LHb	gene expression	ENSRNOG00000050741	0.16	0.12	8.1e-03	0.09	0.03	0.04	0.07	4.3e-03	6.0e-02	4.5e-02	1.0e-02
5	Liver	gene expression	ENSRNOG00000050741	0.05	0.03	1.1e-03	0.01	0.01	0.02	0.01	2.1e-02	7.6e-03	5.2e-03	7.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	2.1	6.9	13.8	-3.5	0.9	0.7	2.7	-3.7
BMI without tail	0.7	1.5	2.5	-1.3	0.7	0.5	1.6	-1.6
Body weight	2.0	8.3	16.6	-2.0	-2.0	3.1	4.1	-2.7
Epididymis fat weight	1.9	4.3	8.1	0.6	2.4	-2.6	-2.8	1.0
Glucose	2.0	3.0	6.2	-0.8	2.5	-2.3	-1.7	-0.3
Heart weight	1.6	2.4	4.5	0.3	2.1	-1.6	-2.0	0.8
Left kidney weight	0.4	1.2	2.8	1.3	0.2	-0.8	-1.7	1.1
Right kidney weight	0.3	0.8	1.8	0.9	-0.9	-0.0	-1.3	0.5
Tail length	1.3	4.0	6.0	2.1	-2.5	2.3	1.7	1.4
Length with tail	1.8	6.7	12.2	0.5	-3.3	3.5	3.1	-0.3
Length without tail	1.7	3.7	6.0	-0.9	-2.1	2.3	2.5	-1.2
Liver weight, left	0.2	0.3	0.8	0.9	0.1	0.0	-0.2	0.8
Liver weight, right	0.2	0.4	1.1	0.8	0.3	-0.1	0.2	1.0
Parametrial fat weight	1.9	3.8	7.1	0.0	2.7	-2.4	-2.5	0.2
Retroperitoneal fat weight	3.4	11.4	19.5	1.2	3.6	-4.4	-4.4	2.0
Intraocular pressure	0.5	0.7	2.8	0.6	-0.3	-0.1	-1.7	0.4
Extensor digitorum longus weight	4.3	17.3	32.2	-1.7	-3.9	5.3	5.7	-2.8
Soleus weight	2.7	7.9	11.6	2.4	1.9	-3.1	-3.4	3.0
Tibialis anterior weight	6.8	23.6	43.1	-0.3	-5.9	6.6	6.0	-2.1
Tibia length	0.7	1.9	6.2	-0.0	-2.5	1.5	0.7	-0.7
Number of licking bursts	0.2	0.2	0.5	-0.5	-0.4	0.2	0.5	-0.7
Food consumed during 24 hour testing period	0.1	0.2	0.7	0.1	-0.8	0.0	-0.3	0.0
Times rat made contact with spout	0.4	0.5	1.1	-0.9	0.1	0.3	1.1	-0.8
Mean time between licks in bursts	0.4	0.6	1.8	0.5	-0.4	0.7	1.4	0.5
Mean num. licks in bursts	0.1	0.2	0.5	-0.0	0.7	-0.4	-0.1	0.2
Std. dev. time between licks in bursts	1.3	1.6	3.7	1.9	-0.2	0.8	0.5	1.8
Water consumed over 24 hours	0.5	0.5	1.1	-0.6	-0.4	0.7	1.1	-0.7
Indifference point 0 sec	0.2	0.3	0.5	-0.4	0.5	-0.7	-0.5	-0.3
Indifference point AUC	2.3	2.7	5.0	-0.6	-1.6	2.2	1.8	-1.5
Indifference point function ln k	5.3	7.5	10.4	2.2	2.2	-3.0	-2.9	3.2
Indifference point function log k	5.3	7.5	10.4	2.2	2.2	-3.0	-2.9	3.2
Delay discounting total patch changes 0 sec	0.0	0.0	0.1	0.3	0.1	-0.3	-0.2	0.2
Delay discounting total patch changes 12 sec	2.8	3.7	5.9	-1.5	-1.3	2.1	2.4	-2.1
Delay discounting total patch changes 18 sec	0.5	0.7	2.0	-0.8	-0.0	0.7	0.6	-1.4
Delay discounting total patch changes 24 sec	1.4	1.8	3.3	-0.3	-1.4	1.7	1.8	-0.9
Delay discounting total patch changes 6 sec	0.7	1.1	2.0	-0.9	-0.3	0.9	1.4	-1.4
Delay discounting time to switch 0 sec	2.4	3.6	8.2	-2.9	0.1	0.5	1.4	-2.7
Delay discounting water rate 0 sec	3.5	5.5	9.6	3.0	0.3	-1.4	-2.6	3.1
Delay discounting water rate 12 sec	6.8	10.2	20.4	4.0	1.3	-2.1	-2.9	4.5
Delay discounting water rate 18 sec	2.5	3.3	6.3	2.1	1.0	-1.6	-1.5	2.5
Delay discounting water rate 24 sec	3.7	5.1	10.2	2.9	0.6	-1.3	-2.1	3.2
Delay discounting water rate 6 sec	3.4	4.9	11.7	3.1	0.5	-0.9	-1.4	3.4
Locomotor activity	1.5	2.4	5.9	2.1	0.3	-0.9	-0.9	2.4
Locomotor testing distance	2.1	3.4	8.6	2.4	0.7	-1.1	-0.9	2.9
Locomotor testing rearing	1.3	2.0	2.9	1.1	1.7	-1.4	-1.1	1.6
Light reinforcement 1	0.1	0.2	0.3	0.5	0.4	-0.5	-0.4	0.6
Light reinforcement 2	0.7	0.9	3.1	0.2	0.0	-1.1	-1.8	0.1
Reaction time number correct	0.5	0.7	1.5	0.6	-1.2	1.1	0.7	0.3
Reaction time mean minus median	2.1	2.7	4.6	-1.5	-1.5	1.6	1.4	-2.2
Reaction time mean minus median AUC	1.3	1.7	3.1	-0.3	-1.6	1.8	1.3	-1.0
Reaction time num false alarms	1.0	1.3	4.0	1.6	-0.3	0.4	0.4	2.0
Reaction time num false alarms AUC	0.9	1.2	2.1	1.2	-0.7	1.0	1.0	1.5
Reaction time trials correct on left	0.5	0.7	1.5	0.6	-1.2	1.1	0.7	0.3
Reaction time trials on left	0.6	0.9	1.9	0.6	-1.4	1.2	0.8	0.3
Reaction time mean	0.1	0.1	0.2	-0.3	-0.2	-0.1	-0.2	-0.4
Reaction time mean AUC	0.1	0.1	0.3	-0.4	-0.1	-0.2	-0.3	-0.5
Median of all reaction times	0.1	0.1	0.3	-0.1	0.3	-0.5	-0.5	-0.1
Reaction time omissions	1.1	1.4	2.5	-0.5	-1.3	1.6	1.4	-0.8
Reaction time false alarm rate	0.4	0.6	1.9	1.0	-0.0	0.2	0.3	1.4
Reaction time premature initiation rate	1.5	2.0	5.0	0.3	-1.4	1.7	2.2	0.2
Reaction time premature initiations	2.7	3.9	7.7	0.5	-2.3	2.5	2.8	0.2
Std. dev. reaction times	0.6	0.8	1.4	-0.8	-0.9	0.8	0.6	-1.2
Reaction time trials completed	0.6	0.9	1.9	0.6	-1.4	1.2	0.8	0.3
Reaction time trials AUC	0.4	0.6	1.2	0.6	-1.1	1.0	0.7	0.4
Social response proportion	1.0	1.1	2.6	-1.6	-0.3	0.1	0.7	-1.5
Social responses	0.1	0.2	0.4	-0.3	-0.4	0.4	0.6	-0.2
Social time	0.3	0.3	0.8	0.2	-0.6	0.7	0.9	0.1
Conditioned locomotion	1.6	1.9	4.1	0.3	-1.6	2.0	1.7	0.0
Cocaine response after cond. corrected	0.7	0.7	1.4	0.7	0.9	-0.7	-0.7	1.2
Cocaine response after cond. not corrected	0.5	0.6	1.0	0.3	1.0	-0.9	-0.6	0.7
Cocaine response before conditioning	0.5	0.6	1.6	-1.0	-0.5	0.2	0.3	-1.3
Saline control response	1.8	2.5	5.9	-0.9	-1.1	1.6	2.4	-1.3
Condit. Reinf. active minus inactive responses	0.8	1.0	1.5	-1.0	0.7	-1.2	-0.9	-1.1
Condit. Reinf. active-inactive response ratio	1.1	1.2	2.3	-0.6	0.6	-1.5	-1.5	-0.7
Condit. Reinf. active responses	1.0	1.5	2.7	-1.6	1.0	-0.9	-0.1	-1.7
Condit. Reinf. inactive responses	0.9	1.1	1.9	-1.4	1.0	0.0	0.9	-1.3
Condit. Reinf. lever presses	1.7	2.3	5.1	-1.7	-0.9	0.9	1.2	-2.3
Condit. Reinf. lever reinforcers received	1.0	1.4	3.2	-1.7	0.6	-0.6	0.1	-1.8
Pavlov. Cond. lever latency	0.3	0.5	1.1	0.7	0.6	-0.5	-0.3	1.1
Pavlov. Cond. magazine entry latency	2.8	3.2	5.3	-2.1	-0.9	1.1	2.0	-2.3
Pavlov. Cond. change in total contacts	1.9	2.6	6.9	-2.2	-0.8	0.5	0.7	-2.6
Pavlov. Cond. index score	1.8	2.3	4.7	-1.9	-1.0	0.9	1.3	-2.2
Pavlov. Cond. latency score	1.5	1.9	3.8	-1.6	-1.0	0.8	1.1	-2.0
Pavlov. Cond. lever contacts	0.3	0.4	0.9	-0.4	-0.9	0.6	0.3	-0.7
Pavlov. Cond. magazine entry number	4.4	5.4	9.1	2.7	1.4	-1.6	-2.5	3.0
Pavlov. Cond. intertrial magazine entries	0.8	1.0	1.9	0.8	0.8	-0.9	-1.4	0.9
Pavlov. Cond. lever-magazine prob. diff.	2.1	2.7	5.2	-2.0	-1.1	1.0	1.5	-2.3
Pavlov. Cond. response bias	1.1	1.6	2.9	-1.4	-1.0	0.9	1.1	-1.7
Conditioned reinforcement - actives	0.2	0.2	0.5	0.3	0.1	-0.4	-0.7	0.4
Conditioned reinforcement - inactives	3.1	3.5	8.4	0.8	1.5	-2.4	-2.9	0.8
Conditioned locomotion	5.0	6.0	10.4	2.2	1.4	-2.5	-3.2	2.5
Intermittent access intake day 1-15 change	0.6	0.6	1.0	1.0	-0.7	-0.1	-1.0	0.6
Intermittent access intake escalation	0.3	0.3	0.8	0.6	-0.4	-0.3	-0.9	0.3
Intermittent access intake escalation 2	0.4	0.4	0.9	1.0	-0.8	0.1	-0.7	0.4
Intermitt. access day 1 inactive lever presses	1.3	1.4	4.0	-0.1	1.1	-1.4	-2.0	0.1
Intermitt. access day 15 inactive lever presses	1.1	1.2	3.3	-0.1	0.7	-1.4	-1.8	-0.2
Intermitt. access escalation Index	3.1	2.8	5.3	0.6	2.3	-2.0	-1.5	1.3
Intermittent access day 1 total infusions	5.6	6.4	13.6	-1.3	3.7	-3.3	-2.3	-0.3
Intermittent access day 15 total infusions	4.7	5.2	9.8	0.1	2.6	-3.1	-3.1	0.5
Intermittent access terminal intake (last 3 days)	3.9	4.2	7.8	-0.4	2.4	-2.7	-2.8	-0.0
Intermittent access total infusions	4.0	4.4	8.1	-1.0	2.8	-2.8	-2.2	-0.4
Intermittent access day 1 locomotion	4.3	4.4	10.3	-1.4	3.2	-2.6	-1.5	-0.7
Intermittent access day 15 total locomotion	3.1	3.3	6.0	-0.2	2.1	-2.4	-2.5	0.1
Intermittent access total locomotion	5.7	6.4	12.3	-1.1	3.3	-3.5	-2.7	-0.6
Intermittent access standard deviation	0.4	0.5	1.3	0.7	0.3	-0.5	-1.1	0.5
Cocaine induced anxiety	0.0	0.0	0.1	0.0	-0.3	0.2	-0.1	-0.0
Post-drug Anxiety	1.1	1.2	3.0	-0.1	-1.7	1.5	0.7	-0.5
Baseline Anxiety	1.5	1.6	3.1	-0.1	-1.8	1.8	1.3	-0.5
Lifetime Intake	3.6	4.0	8.4	-1.0	2.9	-2.6	-2.0	-0.3
Incentive Sensitization - Responses	0.5	0.5	0.7	-0.5	0.8	-0.8	-0.7	-0.7
Incentive Sensitization - Breakpoint	0.6	0.6	0.9	-0.4	0.8	-0.9	-0.9	-0.6
Progressive ratio test 1 active lever presses	1.7	1.7	3.1	0.1	1.5	-1.8	-1.7	0.6
Progressive ratio test 1 breakpoint	1.4	1.4	2.6	0.3	1.3	-1.6	-1.6	0.6
Progressive ratio test 1 inactive lever presses	0.7	0.7	1.7	-0.2	1.2	-1.3	-0.7	0.2
Progressive ratio test 2 active lever presses	2.5	2.7	5.3	-0.0	1.9	-2.3	-2.2	0.0
Progressive ratio test 2 breakpoint	2.7	3.0	5.9	0.6	1.8	-2.3	-2.4	0.7
Progressive ratio test 2 inactive lever presses	5.6	6.4	12.3	0.1	3.1	-3.5	-3.2	0.2
Total sessions with >9 infusions	1.3	1.4	3.4	-0.4	1.8	-1.5	-1.0	0.2
Short access day 1 total inactive lever presses	2.8	3.1	5.3	0.4	2.2	-2.1	-2.3	0.8
Short access day 10 total inactive lever presses	1.6	1.8	3.3	0.8	1.3	-1.4	-1.8	1.2
Short access day 1 total infusions	3.4	3.6	8.1	-0.7	2.8	-2.4	-1.9	-0.1
Short access day 10 total infusions	3.6	4.0	8.3	-2.2	2.9	-2.1	-0.8	-1.3
Short access total infusions	2.0	2.2	5.8	-1.1	2.4	-1.7	-1.0	-0.4
Short access day 1 locomotion	2.7	2.8	6.4	-1.2	2.5	-2.2	-1.1	-0.5
Short access day 10 total locomotion	1.9	2.1	4.6	-1.2	2.1	-1.9	-0.7	-0.6
Short access total locomotion	2.0	2.1	4.9	-1.2	2.2	-1.8	-0.7	-0.6
Compulsive drug intake	2.2	2.2	4.6	0.4	-1.5	2.0	2.2	0.4
One hour access (0.3 mA shock)	5.3	6.2	10.6	0.7	2.8	-3.3	-3.2	1.2
One hour access (shock baseline)	5.1	5.9	12.7	0.2	2.5	-3.2	-3.6	0.5
Number of responses in last shaping day	0.7	0.7	0.9	0.8	0.8	-0.7	-0.9	0.9
Context. condit. distance diff. score	1.2	1.4	2.0	0.7	1.3	-1.3	-1.4	1.0
Locomotion velocity, session 1	0.4	0.5	1.1	1.1	-0.4	0.3	0.4	0.9
Locomotion distance, session 1	0.7	0.9	1.4	-1.1	0.6	-0.2	1.1	-1.2
Locomotion velocity, session 2	1.5	1.8	3.6	-0.8	-0.9	1.5	1.9	-1.3
Locomotion distance, session 2	0.5	0.8	2.2	-0.7	0.1	0.4	1.5	-1.0
Locomotion velocity, session 3	0.3	0.3	0.6	-0.6	0.7	-0.6	-0.1	-0.4
Locomotion distance, session 3	0.0	0.0	0.0	0.2	0.1	-0.0	-0.1	-0.0
Stereotopy head waving bouts, day 3	0.6	0.7	2.2	0.0	1.5	-1.1	-0.6	0.2
Stereotopy head waving duration, day 3	0.9	1.0	2.1	-0.2	1.5	-1.4	-1.0	0.1
Locomotion velocity, session 7	0.6	0.6	1.6	-0.6	1.3	-0.8	-0.4	-0.6
Locomotion distance, session 7	0.1	0.1	0.4	0.0	0.6	0.1	0.5	0.0
Stereotopy head waving bouts, day 7	0.9	1.0	1.3	-1.1	0.9	-0.8	-1.1	-1.2
Stereotopy head waving duration, day 7	1.6	1.9	5.2	-2.1	0.3	0.2	0.3	-2.3
Locomotion velocity, session 8	0.7	0.9	1.9	0.4	-1.0	1.2	1.4	0.0
Locomotion distance, session 8	0.2	0.3	0.6	0.1	0.8	-0.8	-0.3	0.0
Degree of sensitization distance	0.2	0.2	0.5	-0.5	0.7	-0.2	0.4	-0.3
Degree of sensitization stereotypy	1.0	1.1	3.2	-1.5	-0.1	0.4	-0.1	-1.8
Condit. Reinf. active minus inactive responses	0.3	0.3	0.6	-0.8	-0.1	-0.1	0.5	-0.8
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.4	-0.6	-0.0	-0.4	0.1	-0.5
Condit. Reinf. active responses	0.2	0.2	0.4	-0.6	-0.2	0.0	0.3	-0.7
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.2	0.1	0.0	-0.1	-0.4
Incentive salience index mean	0.3	0.4	0.8	-0.9	-0.1	0.1	0.7	-0.9
Condit. Reinf. lever presses	0.2	0.3	0.4	-0.5	-0.6	0.5	0.5	-0.6
Time in familiar zone, hab. session 1	0.6	0.5	1.1	-0.7	0.7	-1.0	-0.5	-0.5
Time in novel zone, hab. session 1	0.7	0.7	1.9	1.1	-0.1	0.3	0.0	1.4
Total zone transitions, hab. session 1	0.5	0.6	1.5	-0.5	-0.5	0.7	1.2	-0.8
Total locomotion distance, hab. session 1	0.2	0.3	0.5	0.2	0.7	-0.7	-0.5	0.2
Locomotion velocity, hab. session 1	0.0	0.0	0.1	0.2	0.3	-0.2	-0.0	-0.0
Time in familiar zone, hab. session 2	0.6	0.6	1.1	1.0	-0.3	0.7	0.6	1.0
Time in novel zone, hab. session 2	0.6	0.6	1.5	-1.2	0.5	-0.5	-0.2	-1.1
Total zone transitions, hab. session 2	2.5	3.2	6.6	-2.5	1.2	-0.1	1.4	-2.6
Total locomotion distance, hab. session 2	0.8	1.0	2.3	-1.1	1.5	-0.8	0.1	-1.0
Locomotion velocity, hab. session 2	0.9	1.2	2.4	-1.1	1.6	-1.1	-0.2	-1.0
Novel to familiar place preference ratio	1.1	1.2	3.2	-1.5	-0.4	0.3	0.2	-1.8
Novelty place preference	0.8	0.9	2.4	-1.4	-0.1	-0.1	-0.2	-1.5
Time in novel zone, NPP test	0.6	0.7	1.9	-1.2	0.0	-0.1	-0.2	-1.4
Total zone transitions, NPP test	1.1	1.6	3.1	-1.1	-0.4	0.8	1.7	-1.6
Total locomotion distance, NPP test	0.1	0.1	0.2	-0.1	0.4	-0.3	0.4	-0.3
Locomotion velocity, NPP test	0.1	0.1	0.1	-0.1	0.2	-0.2	0.4	-0.3
Pavlov. Cond. lever latency	0.1	0.2	0.4	0.5	0.1	-0.4	-0.3	0.6
Pavlov. Cond. magazine entry latency	0.8	1.0	2.1	-1.4	0.7	-0.5	-0.1	-1.5
Pavlov. Cond. change in total contacts	0.6	0.6	1.4	-1.0	0.1	-0.6	-0.6	-1.2
Pavlov. Cond. index score	0.1	0.1	0.4	-0.4	-0.2	0.1	-0.1	-0.6
Pavlov. Cond. latency score	0.1	0.1	0.3	-0.4	0.1	-0.0	-0.1	-0.6
Pavlov. Cond. lever contacts	0.0	0.0	0.0	-0.1	0.1	0.1	0.0	-0.2
Pavlov. Cond. magazine entry number	0.2	0.2	0.5	0.3	0.6	-0.3	0.1	0.7
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.5	0.5	-0.2	-0.1	-0.7	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.6	-0.5	-0.3	0.2	0.1	-0.8
Pavlov. Cond. response bias	0.1	0.1	0.3	-0.2	-0.3	0.2	-0.1	-0.5
Bone: apparent density	1.6	2.7	6.5	-2.5	1.3	-0.5	0.5	-2.1
Bone surface	3.3	5.9	13.5	-3.4	-0.4	1.1	1.8	-3.7
Bone volume	2.0	3.4	8.4	-2.8	0.4	0.1	0.8	-2.9
Bone: connectivity density	2.5	3.9	8.9	-3.0	0.5	0.5	1.6	-2.8
Bone: cortical apparent density	0.2	0.3	0.5	0.3	-0.6	0.7	0.7	0.1
Bone: cortical area	0.6	0.9	2.1	0.1	-1.5	1.3	0.7	-0.3
Bone: cortical porosity	0.3	0.4	0.8	-0.9	0.7	-0.4	0.3	-0.6
Bone: cortical porosity	0.3	0.4	0.7	-0.8	0.2	0.3	0.8	-0.6
Bone: cortical thickness	3.4	5.6	11.4	1.0	-3.0	3.4	2.5	0.3
Bone: cortical thickness	1.9	2.2	3.8	1.4	-1.6	1.9	1.5	0.9
Bone: cortical tissue density	0.3	0.4	0.7	0.4	-0.7	0.8	0.8	0.1
Bone: elastic displacement	1.9	2.2	5.5	2.3	-0.5	0.3	-0.2	2.3
Bone: elastic work	1.7	2.2	3.4	1.5	-1.5	1.8	1.6	0.9
Bone: endosteal estimation	1.3	2.7	5.1	-0.9	2.1	-2.3	-1.6	-0.7
Bone: endosteal perimeter	2.3	4.8	9.2	-1.7	2.3	-3.0	-2.1	-1.4
Bone: final force	1.4	2.2	3.4	-0.8	-1.4	1.7	1.9	-1.5
Bone: final moment	1.2	1.9	3.0	-0.8	-1.3	1.6	1.7	-1.4
Bone: marrow area	1.3	2.8	5.3	-0.9	2.2	-2.3	-1.6	-0.6
Bone: maximum diameter	0.1	0.2	0.6	-0.3	-0.8	0.1	-0.3	-0.6
Bone: maximum force	2.3	3.9	9.2	-2.3	-0.8	1.1	1.8	-3.0
Bone: maximum moment	1.9	3.3	7.6	-2.1	-0.7	1.0	1.7	-2.8
Bone: minimum diameter	1.7	3.1	5.0	-1.5	2.2	-2.1	-1.4	-1.3
Bone: periosteal estimation	0.1	0.2	0.5	-0.4	0.2	-0.4	-0.6	-0.7
Bone: periosteal perimeter	0.3	0.5	1.4	-1.0	0.2	-0.4	-0.2	-1.2
Bone: post-yield work	6.5	8.9	19.3	-4.4	2.1	-1.9	-0.4	-4.1
Bone: stiffness	2.3	3.7	9.6	-2.6	-0.4	0.7	1.3	-3.1
Bone: tissue strength	0.3	0.3	0.7	-0.7	0.1	-0.3	-0.2	-0.9
Bone: trabecular number	1.7	2.6	6.7	-2.6	0.9	-0.2	0.4	-2.3
Bone: trabecular spacing	0.5	0.6	1.8	1.4	-0.0	-0.2	-0.1	1.1
Bone: trabecular thickness	1.2	1.4	2.3	-1.4	1.5	-1.3	-0.7	-0.7
Bone: trabecular tissue density	2.2	3.1	6.1	1.5	0.7	-1.9	-2.5	1.8
Breakpoint value in progressive ratio session	1.9	2.1	2.7	-1.2	-1.7	1.6	1.6	-1.3
Distance traveled before self-admin	0.3	0.3	0.6	-0.4	-0.7	0.4	0.3	-0.8
Distance traveled after self-admin	0.3	0.3	0.8	-0.6	-0.7	0.3	0.0	-0.9
Delta time in closed arm before/after self-admin	0.8	0.7	1.4	0.7	-0.2	1.1	1.2	0.8
Delta time in open arm before/after self-admin	0.3	0.2	0.6	-0.2	-0.3	0.2	-0.8	-0.6
Diff in mean of infusions in LGA sessions	0.4	0.4	1.0	-0.0	-1.0	1.0	0.3	-0.3
Extinction: sum of active levers before priming	2.7	2.7	3.7	-1.8	-1.1	1.4	1.8	-1.9
Active lever presses in extinction session 6	2.4	2.3	5.8	-0.2	-2.4	2.0	1.2	-0.6
Delta distance traveled before/after self-admin	0.0	0.0	0.0	-0.0	-0.1	0.0	0.0	0.1
Delta ambulatory time before/after self-admin	0.0	0.0	0.1	0.1	-0.2	0.2	0.3	0.2
Time in closed arm before self-admin	0.3	0.3	0.5	-0.6	0.2	-0.5	-0.5	-0.7
Time in closed arm after self-admin	0.0	0.0	0.2	-0.0	0.0	0.2	0.4	0.0
Time in open arm before self-admin	0.7	0.7	2.1	1.0	0.6	-0.2	0.2	1.4
Time in open arm after self-admin	0.3	0.4	0.7	0.8	-0.0	0.1	-0.8	0.8
Sum of active levers in priming session hrs 5-6	1.9	1.9	6.6	0.2	-2.6	1.6	0.6	-0.2
Time to tail flick, vehicle, before self-admin	0.5	0.6	1.1	-1.0	-0.0	0.3	0.8	-1.0
Time to tail flick, vehicle, after self-admin	0.9	0.9	2.3	-0.8	-0.0	1.0	1.5	-0.8
Time to tail flick, test, before self-admin	0.9	0.9	2.9	-0.5	1.7	-1.1	-0.2	-0.2
Time to tail flick, test, after self-admin	0.0	0.0	0.1	-0.2	-0.0	0.2	0.2	0.0
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.6	-0.6	0.0	0.5	0.8	-0.7
Delta time to tail flick, test, before/after SA	2.0	1.8	4.2	0.8	-2.0	1.8	0.8	0.4
Ambulatory time before self-admin	0.6	0.6	1.9	-0.8	-0.7	0.3	-0.2	-1.4
Ambulatory time after self-admin	0.9	1.0	1.9	-1.3	0.2	-0.8	-0.8	-1.4
Total heroin consumption	2.5	3.0	4.2	-1.2	-2.1	2.0	1.9	-1.4
Area under the delay curve	0.7	0.7	1.6	-0.6	1.3	-1.2	0.2	-0.3
Delay disc. indifference point, 0s delay	0.9	1.0	2.9	0.3	1.7	-1.2	0.2	0.7
Delay disc. indifference point, 16s delay	1.4	1.4	3.3	-1.0	1.1	-1.8	-1.0	-0.7
Delay disc. indifference point, 2s delay	0.2	0.2	0.6	0.1	0.5	-0.8	-0.4	0.1
Delay disc. indifference point, 24s delay	0.2	0.2	0.5	0.4	0.2	-0.1	0.4	0.7
Delay disc. indifference point, 4s delay	0.5	0.5	1.9	0.0	1.4	-0.9	0.1	0.4
Delay disc. indifference point, 8s delay	0.4	0.4	1.1	0.0	1.0	-0.8	0.5	0.3
Delay discount exponential model param	0.5	0.6	1.3	0.6	-1.1	1.1	-0.2	0.2
Delay discount hyperbolic model param	0.4	0.5	1.1	0.4	-1.0	1.0	-0.3	0.1
Fecal boli incidents, locomotor time 1	0.4	0.4	1.0	-0.5	-0.4	0.4	-0.6	-1.0
Change in fecal boli incidents, locomotor task	0.4	0.4	1.0	-0.2	0.8	-0.4	1.0	0.2
Time >=10cm from walls, locomotor time 1	2.6	2.6	3.7	-1.9	1.7	-1.9	-0.9	-1.4
Bouts of movement, locomotor time 1	1.0	1.1	1.8	-0.7	-1.3	1.0	0.9	-1.1
Total resting periods, locomotor time 1	0.7	0.8	1.5	-1.0	-1.0	0.7	0.6	-1.2
Rest time, locomotor task time 1	1.0	1.1	1.9	1.0	0.1	-1.0	-1.4	1.2
Distance moved, locomotor task time 1	0.5	0.6	1.1	-1.1	0.6	-0.1	0.7	-1.0
Vertical activity count, locomotor time 1	0.6	0.6	0.8	0.7	0.9	-0.8	-0.6	0.7
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.6	0.1	-0.5	-0.4	-0.4
Bouts of movement, locomotor time 2	0.5	0.5	0.8	-0.5	-0.4	0.7	0.9	-0.8
Total resting periods, locomotor time 2	0.3	0.3	0.7	-0.6	-0.2	0.4	0.5	-0.8
Rest time, locomotor task time 2	1.3	1.6	2.4	0.8	1.1	-1.5	-1.5	1.1
Distance moved, locomotor task time 2	0.7	0.8	1.8	-0.2	-1.1	0.9	1.4	-0.4
Vertical activity count, locomotor time 2	1.3	1.4	2.8	1.7	-0.9	0.8	0.7	1.5
Weight adjusted by age	2.1	2.3	3.5	-0.8	-1.9	1.8	1.8	-1.0
Seeking ratio, delayed vs. immediate footshock	0.4	0.4	0.8	-0.9	0.6	-0.7	0.3	-0.6
Locomotion in novel chamber	2.7	3.3	6.4	0.9	1.5	-2.5	-2.5	1.0
Locomotion in novel chamber post-restriction	1.7	2.0	3.9	0.9	1.2	-1.6	-2.0	1.1
Progressive ratio	2.1	2.4	5.9	-2.4	0.5	0.3	1.4	-2.0
Food seeking constrained by brief footshock	0.4	0.5	1.1	0.2	-0.8	0.8	1.1	0.1
Seeking ratio, punishment vs. effort	1.8	2.2	5.6	2.4	-0.3	-0.3	-0.7	2.2
Run reversals in cocaine runway, females	0.8	0.8	2.0	-0.9	0.9	0.2	1.4	-0.6
Run reversals in cocaine runway, males	1.8	1.8	4.2	2.1	-1.1	1.0	-0.2	1.6
Latency to leave start box in cocaine runway	0.7	0.8	1.4	-1.2	0.7	-0.7	-0.3	-1.2
Latency to leave start box in cocaine runway, F	0.3	0.3	0.6	-0.6	0.5	-0.5	-0.0	-0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.5	-0.0	-0.2	-0.0	-0.5
Cd content in liver	0.9	1.0	2.5	1.0	0.2	-0.8	-1.6	0.8
Co content in liver	1.9	2.3	6.4	2.2	0.2	-0.1	-0.6	2.5
Cu content in liver	0.2	0.2	0.3	-0.5	-0.2	0.3	0.5	-0.5
Fe content in liver	0.1	0.1	0.3	0.2	-0.5	0.5	0.2	-0.1
K content in liver	1.5	1.5	2.9	-1.7	-0.0	0.5	1.3	-1.7
Mg content in liver	2.3	2.4	5.0	-2.2	1.5	-0.9	0.3	-1.9
Mn content in liver	1.9	2.2	4.0	-1.5	-1.3	1.3	1.3	-2.0
Na content in liver	0.7	0.7	2.4	0.2	-1.6	0.8	0.6	-0.1
Rb content in liver	1.5	1.9	4.8	-0.6	2.2	-1.7	-1.2	-0.1
Se content in liver	0.9	1.1	2.6	-1.3	0.5	-0.6	-0.6	-1.6
Sr content in liver	2.2	2.0	4.3	0.1	-2.1	1.9	1.3	-0.4
Zn content in liver	0.7	0.8	1.2	-1.0	-0.7	0.8	1.1	-0.9