Hub : Genes

Syngr2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000050547	0.03	0.03	1.1e-03	0.02	0.02	0.01	0.02	1.3e-03	2.3e-03	5.0e-02	4.1e-03
2	Brain	gene expression	ENSRNOG00000050547	0.04	0.03	4.4e-03	0.03	0.03	0.02	0.03	1.5e-03	1.8e-03	3.9e-03	1.5e-03
3	Liver	gene expression	ENSRNOG00000050547	0.07	0.05	1.3e-07	0.06	0.05	0.05	0.05	3.7e-07	1.1e-06	5.8e-06	1.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.1	0.4	0.6	-0.7	0.5	0.6
BMI without tail	0.7	1.4	2.7	0.9	1.7	-0.8
Body weight	0.9	3.8	4.6	-2.1	-1.6	2.1
Epididymis fat weight	0.3	0.7	1.1	-1.1	0.2	0.9
Glucose	0.1	0.1	0.2	-0.3	0.4	0.4
Heart weight	0.4	0.6	0.9	-1.0	-0.4	0.9
Left kidney weight	3.7	10.6	11.3	-3.4	-3.0	3.4
Right kidney weight	1.4	3.9	4.0	-2.0	-2.0	1.9
Tail length	0.1	0.3	0.5	0.7	0.4	-0.5
Length with tail	1.4	5.0	5.7	-2.1	-2.4	2.1
Length without tail	4.5	9.8	11.0	-3.3	-3.0	3.0
Liver weight, left	3.1	5.0	5.7	-2.4	-2.0	2.3
Liver weight, right	1.4	2.3	2.4	-1.5	-1.5	1.5
Parametrial fat weight	0.1	0.2	0.3	-0.5	-0.2	0.4
Retroperitoneal fat weight	0.9	2.9	3.8	-1.9	-1.1	1.9
Intraocular pressure	0.4	0.6	1.7	0.2	1.3	-0.2
Extensor digitorum longus weight	1.0	3.8	4.6	1.8	2.1	-1.9
Soleus weight	0.5	1.5	1.5	1.2	1.2	-1.2
Tibialis anterior weight	0.1	0.3	0.4	0.6	0.5	-0.6
Tibia length	14.1	39.7	40.9	-6.3	-6.2	6.4
Number of licking bursts	0.1	0.1	0.2	-0.2	-0.4	0.2
Food consumed during 24 hour testing period	0.1	0.1	0.2	0.2	-0.1	-0.4
Times rat made contact with spout	0.3	0.3	0.4	0.6	0.4	-0.7
Mean time between licks in bursts	0.0	0.0	0.0	-0.0	-0.0	-0.1
Mean num. licks in bursts	0.7	0.9	1.0	0.9	1.0	-0.9
Std. dev. time between licks in bursts	1.8	2.2	2.4	1.6	1.4	-1.4
Water consumed over 24 hours	0.4	0.5	0.7	0.8	0.5	-0.8
Indifference point 0 sec	0.7	1.1	1.2	1.0	1.0	-1.1
Indifference point AUC	2.4	2.8	3.3	1.8	1.5	-1.8
Indifference point function ln k	0.2	0.3	0.5	-0.7	-0.1	0.6
Indifference point function log k	0.2	0.3	0.5	-0.7	-0.1	0.6
Delay discounting total patch changes 0 sec	1.0	1.6	1.9	1.2	1.2	-1.4
Delay discounting total patch changes 12 sec	3.7	5.0	5.3	2.2	2.2	-2.3
Delay discounting total patch changes 18 sec	1.9	2.5	2.8	1.7	1.5	-1.5
Delay discounting total patch changes 24 sec	0.0	0.0	0.1	-0.2	-0.3	0.1
Delay discounting total patch changes 6 sec	2.1	3.2	3.3	1.8	1.8	-1.8
Delay discounting time to switch 0 sec	0.3	0.5	0.9	-0.7	-0.4	1.0
Delay discounting water rate 0 sec	0.6	0.9	1.3	1.0	0.8	-1.1
Delay discounting water rate 12 sec	0.4	0.5	1.5	0.1	1.2	-0.3
Delay discounting water rate 18 sec	0.2	0.3	0.6	0.5	0.8	-0.4
Delay discounting water rate 24 sec	1.5	2.0	3.1	1.3	1.8	-1.1
Delay discounting water rate 6 sec	0.1	0.1	0.1	0.2	0.4	-0.3
Locomotor activity	0.1	0.2	0.4	0.1	-0.6	-0.4
Locomotor testing distance	0.0	0.1	0.1	-0.1	-0.3	-0.2
Locomotor testing rearing	1.0	1.6	2.3	1.4	0.7	-1.5
Light reinforcement 1	1.8	3.4	3.8	2.0	1.7	-1.8
Light reinforcement 2	0.1	0.1	0.2	0.3	0.5	-0.2
Reaction time number correct	3.6	5.2	6.4	2.2	2.5	-2.1
Reaction time mean minus median	0.7	1.0	1.1	-1.0	-1.0	0.9
Reaction time mean minus median AUC	0.9	1.1	1.5	-1.1	-1.2	0.8
Reaction time num false alarms	0.0	0.0	0.0	-0.1	-0.0	0.1
Reaction time num false alarms AUC	0.0	0.1	0.1	0.2	0.3	-0.2
Reaction time trials correct on left	3.6	5.2	6.4	2.2	2.5	-2.1
Reaction time trials on left	3.6	5.1	6.3	2.2	2.5	-2.0
Reaction time mean	0.1	0.1	0.2	-0.3	-0.4	0.2
Reaction time mean AUC	0.0	0.0	0.0	-0.2	-0.2	0.1
Median of all reaction times	0.0	0.0	0.1	-0.1	-0.3	0.0
Reaction time omissions	0.7	1.0	1.1	-1.0	-0.9	1.1
Reaction time false alarm rate	0.6	0.8	1.0	-0.9	-1.0	0.8
Reaction time premature initiation rate	3.1	4.2	4.4	2.0	2.0	-2.1
Reaction time premature initiations	6.5	9.2	10.4	2.9	3.2	-2.9
Std. dev. reaction times	0.1	0.2	0.3	-0.5	-0.4	0.3
Reaction time trials completed	3.6	5.1	6.3	2.2	2.5	-2.0
Reaction time trials AUC	4.3	6.1	7.6	2.4	2.8	-2.2
Social response proportion	0.1	0.1	0.2	0.5	0.3	-0.4
Social responses	0.2	0.2	0.3	0.6	-0.1	-0.6
Social time	0.3	0.4	0.5	0.7	0.6	-0.7
Conditioned locomotion	0.1	0.1	0.2	0.4	0.3	-0.3
Cocaine response after cond. corrected	0.3	0.3	0.4	-0.6	-0.3	0.6
Cocaine response after cond. not corrected	0.1	0.1	0.2	-0.3	-0.4	0.2
Cocaine response before conditioning	0.3	0.4	0.6	0.7	-0.0	-0.7
Saline control response	0.3	0.4	0.6	0.8	-0.3	-0.7
Condit. Reinf. active minus inactive responses	0.3	0.4	0.8	-0.4	-0.9	0.4
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	-0.1	-0.5	0.2
Condit. Reinf. active responses	0.0	0.1	0.1	0.2	0.1	-0.4
Condit. Reinf. inactive responses	0.5	0.7	0.9	0.7	0.8	-0.9
Condit. Reinf. lever presses	1.0	1.4	2.1	1.2	0.8	-1.4
Condit. Reinf. lever reinforcers received	0.1	0.2	0.2	0.3	0.4	-0.4
Pavlov. Cond. lever latency	0.8	1.1	1.5	-1.0	-0.8	1.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.4	-0.0	0.6	-0.1
Pavlov. Cond. change in total contacts	0.5	0.7	1.0	0.7	1.0	-0.8
Pavlov. Cond. index score	0.3	0.3	0.5	0.5	0.5	-0.7
Pavlov. Cond. latency score	0.1	0.1	0.2	0.3	0.3	-0.4
Pavlov. Cond. lever contacts	0.9	1.3	2.1	1.2	0.5	-1.4
Pavlov. Cond. magazine entry number	0.3	0.3	0.6	-0.4	-0.8	0.5
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.7	0.7	-0.3	-0.8
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.5	0.6	0.6	-0.7
Pavlov. Cond. response bias	0.5	0.7	1.0	0.8	0.6	-1.0
Conditioned reinforcement - actives	0.7	0.7	0.9	0.8	1.0	-0.7
Conditioned reinforcement - inactives	0.1	0.1	0.2	-0.3	-0.3	0.5
Conditioned locomotion	0.7	0.9	1.0	0.9	1.0	-0.9
Intermittent access intake day 1-15 change	0.0	0.0	0.1	0.2	-0.2	0.3
Intermittent access intake escalation	0.1	0.1	0.1	0.4	0.1	0.1
Intermittent access intake escalation 2	0.3	0.3	0.5	0.7	0.5	-0.3
Intermitt. access day 1 inactive lever presses	2.0	2.1	2.6	-1.4	-1.6	1.4
Intermitt. access day 15 inactive lever presses	0.4	0.4	0.6	0.8	0.5	-0.6
Intermitt. access escalation Index	0.5	0.4	0.5	-0.7	-0.7	0.6
Intermittent access day 1 total infusions	0.3	0.3	0.5	-0.7	-0.3	0.6
Intermittent access day 15 total infusions	0.0	0.0	0.0	-0.1	-0.0	0.2
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.4	-0.5	-0.3	0.6
Intermittent access total infusions	0.2	0.2	0.4	-0.6	-0.2	0.4
Intermittent access day 1 locomotion	0.3	0.3	0.4	0.4	0.7	-0.5
Intermittent access day 15 total locomotion	0.1	0.1	0.1	-0.4	-0.3	0.4
Intermittent access total locomotion	0.1	0.1	0.2	0.3	0.4	-0.4
Intermittent access standard deviation	5.0	5.4	6.8	-2.2	-2.1	2.6
Cocaine induced anxiety	0.2	0.2	0.3	-0.3	-0.6	0.4
Post-drug Anxiety	0.0	0.0	0.1	0.3	0.0	-0.2
Baseline Anxiety	0.0	0.0	0.0	-0.1	-0.0	-0.1
Lifetime Intake	0.3	0.3	0.6	-0.8	-0.2	0.6
Incentive Sensitization - Responses	0.8	0.8	1.0	-1.0	-0.8	0.9
Incentive Sensitization - Breakpoint	1.1	1.1	1.2	-1.1	-1.0	1.0
Progressive ratio test 1 active lever presses	0.1	0.1	0.4	0.1	0.6	-0.3
Progressive ratio test 1 breakpoint	0.1	0.1	0.4	-0.0	0.6	-0.1
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.4	-0.3	-0.6	0.4
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	0.0	0.6	-0.2
Progressive ratio test 2 breakpoint	0.2	0.2	0.4	0.2	0.6	-0.3
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.0	-0.0	0.2	0.1
Total sessions with >9 infusions	1.0	1.1	1.8	-1.3	-0.6	1.1
Short access day 1 total inactive lever presses	0.2	0.3	0.5	-0.7	-0.3	0.4
Short access day 10 total inactive lever presses	0.5	0.6	0.7	-0.7	-0.8	0.8
Short access day 1 total infusions	1.2	1.2	2.3	-1.5	-0.7	0.9
Short access day 10 total infusions	1.6	1.7	2.9	-1.7	-0.8	1.3
Short access total infusions	0.3	0.4	0.8	-0.9	-0.1	0.5
Short access day 1 locomotion	0.3	0.3	0.6	-0.8	-0.5	0.5
Short access day 10 total locomotion	0.4	0.5	0.6	-0.8	-0.5	0.7
Short access total locomotion	1.1	1.1	1.6	-1.3	-0.8	1.0
Compulsive drug intake	0.5	0.5	1.0	0.5	1.0	-0.5
One hour access (0.3 mA shock)	0.2	0.2	0.6	0.1	0.8	-0.2
One hour access (shock baseline)	0.0	0.0	0.0	-0.1	-0.2	0.2
Number of responses in last shaping day	2.6	2.6	3.3	-1.5	-1.8	1.5
Context. condit. distance diff. score	0.2	0.3	0.4	-0.6	0.0	0.7
Locomotion velocity, session 1	0.7	0.7	2.0	-0.2	-1.4	0.4
Locomotion distance, session 1	2.2	2.9	3.7	1.9	1.2	-1.8
Locomotion velocity, session 2	1.0	1.2	1.6	1.2	0.6	-1.3
Locomotion distance, session 2	6.1	8.8	10.5	3.2	2.3	-3.2
Locomotion velocity, session 3	0.2	0.2	0.7	0.0	-0.8	-0.0
Locomotion distance, session 3	0.1	0.1	0.3	0.2	0.5	-0.1
Stereotopy head waving bouts, day 3	1.9	2.2	2.6	-1.6	-1.4	1.5
Stereotopy head waving duration, day 3	1.8	2.2	2.4	-1.6	-1.5	1.4
Locomotion velocity, session 7	0.1	0.1	0.1	0.4	0.2	-0.2
Locomotion distance, session 7	3.1	3.9	5.0	1.9	2.2	-1.7
Stereotopy head waving bouts, day 7	4.1	4.6	5.7	-2.2	-1.9	2.4
Stereotopy head waving duration, day 7	5.8	7.1	7.9	-2.5	-2.8	2.7
Locomotion velocity, session 8	0.3	0.3	0.6	-0.4	-0.7	0.5
Locomotion distance, session 8	2.6	3.8	4.2	1.9	2.1	-1.9
Degree of sensitization distance	3.7	3.7	4.1	2.0	1.8	-2.0
Degree of sensitization stereotypy	2.0	2.1	2.9	-1.4	-1.2	1.7
Condit. Reinf. active minus inactive responses	0.1	0.1	0.3	0.4	0.1	-0.5
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.5	0.6	0.2	-0.7
Condit. Reinf. active responses	0.6	0.7	1.2	0.9	0.3	-1.1
Condit. Reinf. inactive responses	0.5	0.6	0.9	0.9	0.5	-0.9
Incentive salience index mean	0.1	0.1	0.1	0.2	-0.2	-0.3
Condit. Reinf. lever presses	0.1	0.1	0.1	0.3	-0.3	-0.3
Time in familiar zone, hab. session 1	0.0	0.0	0.0	0.1	0.1	-0.1
Time in novel zone, hab. session 1	0.1	0.1	0.2	-0.4	-0.4	0.3
Total zone transitions, hab. session 1	2.9	4.0	5.3	2.3	1.4	-2.2
Total locomotion distance, hab. session 1	1.8	2.6	3.3	1.8	1.1	-1.8
Locomotion velocity, hab. session 1	2.3	3.4	4.3	2.1	1.3	-2.0
Time in familiar zone, hab. session 2	0.2	0.2	0.6	0.0	0.8	0.0
Time in novel zone, hab. session 2	0.2	0.2	0.5	-0.3	-0.7	0.3
Total zone transitions, hab. session 2	7.4	9.5	10.3	3.2	2.8	-3.2
Total locomotion distance, hab. session 2	6.1	8.1	8.5	2.8	2.8	-2.9
Locomotion velocity, hab. session 2	6.2	8.4	9.2	3.0	2.7	-3.0
Novel to familiar place preference ratio	2.8	2.9	3.1	1.6	1.8	-1.8
Novelty place preference	2.1	2.2	2.3	1.4	1.5	-1.5
Time in novel zone, NPP test	2.5	2.7	2.9	1.5	1.7	-1.6
Total zone transitions, NPP test	5.1	7.3	8.3	2.8	2.3	-2.9
Total locomotion distance, NPP test	7.3	10.1	10.9	3.2	3.0	-3.3
Locomotion velocity, NPP test	6.2	8.8	9.5	3.0	2.8	-3.1
Pavlov. Cond. lever latency	0.8	1.0	2.6	0.5	1.6	-0.4
Pavlov. Cond. magazine entry latency	2.2	2.9	4.7	-1.4	-2.2	1.4
Pavlov. Cond. change in total contacts	0.2	0.2	0.3	0.5	0.1	-0.6
Pavlov. Cond. index score	1.7	2.2	4.1	-1.1	-2.0	1.1
Pavlov. Cond. latency score	2.3	3.0	5.2	-1.4	-2.3	1.3
Pavlov. Cond. lever contacts	0.3	0.3	0.9	-0.2	-1.0	0.1
Pavlov. Cond. magazine entry number	3.2	4.0	5.7	1.8	2.4	-1.8
Pavlov. Cond. intertrial magazine entries	2.3	2.8	3.0	1.6	1.7	-1.7
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	3.1	-0.8	-1.8	0.8
Pavlov. Cond. response bias	1.5	1.8	3.4	-1.1	-1.8	1.0
Bone: apparent density	1.4	2.3	2.6	1.6	1.4	-1.5
Bone surface	0.2	0.3	0.5	-0.4	-0.7	0.5
Bone volume	0.0	0.1	0.1	0.3	-0.0	-0.3
Bone: connectivity density	2.0	3.2	3.4	1.8	1.7	-1.8
Bone: cortical apparent density	1.7	2.2	2.4	1.4	1.6	-1.5
Bone: cortical area	2.7	4.1	4.2	-2.0	-2.0	2.1
Bone: cortical porosity	1.8	1.9	2.8	-1.2	-1.7	1.2
Bone: cortical porosity	2.7	2.9	3.8	-1.6	-1.9	1.6
Bone: cortical thickness	0.1	0.2	0.2	-0.4	-0.5	0.4
Bone: cortical thickness	0.1	0.1	0.2	-0.3	-0.5	0.3
Bone: cortical tissue density	1.8	2.4	2.6	1.5	1.6	-1.5
Bone: elastic displacement	1.3	1.4	1.6	1.2	1.1	-1.3
Bone: elastic work	0.1	0.2	0.2	-0.5	-0.3	0.5
Bone: endosteal estimation	1.1	2.3	2.5	-1.6	-1.4	1.6
Bone: endosteal perimeter	4.5	9.2	10.0	-2.9	-3.2	3.0
Bone: final force	0.8	1.4	1.5	-1.2	-1.2	1.1
Bone: final moment	0.9	1.5	1.6	-1.3	-1.2	1.1
Bone: marrow area	1.1	2.4	2.6	-1.6	-1.4	1.6
Bone: maximum diameter	7.3	13.4	13.8	-3.6	-3.6	3.7
Bone: maximum force	0.9	1.6	1.9	-1.4	-0.9	1.4
Bone: maximum moment	0.9	1.6	2.0	-1.4	-1.0	1.4
Bone: minimum diameter	2.3	4.3	6.1	-1.9	-2.5	1.8
Bone: periosteal estimation	2.8	5.7	5.9	-2.4	-2.3	2.4
Bone: periosteal perimeter	6.4	10.6	11.4	-3.1	-3.4	3.3
Bone: post-yield work	0.6	0.8	1.3	0.8	1.1	-0.7
Bone: stiffness	1.4	2.3	2.5	-1.5	-1.4	1.6
Bone: tissue strength	1.0	1.0	1.9	0.6	1.4	-0.8
Bone: trabecular number	0.6	0.9	1.2	1.1	0.7	-1.0
Bone: trabecular spacing	0.7	0.9	1.1	-1.0	-0.9	1.0
Bone: trabecular thickness	0.9	1.1	1.5	1.1	0.7	-1.2
Bone: trabecular tissue density	0.5	0.7	1.2	-0.7	-1.1	0.7
Breakpoint value in progressive ratio session	0.3	0.4	0.6	-0.8	0.3	0.6
Distance traveled before self-admin	1.4	1.5	2.6	-0.9	-1.6	1.0
Distance traveled after self-admin	1.5	1.6	2.1	1.1	1.5	-1.3
Delta time in closed arm before/after self-admin	0.3	0.3	0.4	-0.7	-0.1	0.6
Delta time in open arm before/after self-admin	1.3	1.2	2.1	1.5	0.7	-1.0
Diff in mean of infusions in LGA sessions	0.9	1.1	1.5	-1.2	-0.6	1.1
Extinction: sum of active levers before priming	0.0	0.0	0.0	-0.1	-0.1	-0.0
Active lever presses in extinction session 6	0.4	0.4	0.9	-0.2	1.0	-0.4
Delta distance traveled before/after self-admin	4.0	4.3	6.3	1.8	2.5	-1.9
Delta ambulatory time before/after self-admin	4.8	5.2	7.7	1.9	2.8	-2.1
Time in closed arm before self-admin	0.0	0.0	0.0	0.1	-0.1	0.1
Time in closed arm after self-admin	2.7	2.8	3.8	-1.8	-1.2	2.0
Time in open arm before self-admin	0.2	0.2	0.5	-0.7	-0.1	0.2
Time in open arm after self-admin	0.9	1.0	1.2	1.0	1.1	-1.0
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.3	-0.5	-0.3	0.4
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.2	1.1	0.3	-1.0
Time to tail flick, vehicle, after self-admin	1.6	1.7	2.8	-1.4	-0.6	1.7
Time to tail flick, test, before self-admin	0.3	0.3	0.6	0.5	-0.3	-0.8
Time to tail flick, test, after self-admin	0.8	0.8	1.3	-1.2	-0.6	0.9
Delta time to tail flick, vehicle, before/after SA	0.5	0.4	0.8	-0.7	0.1	0.9
Delta time to tail flick, test, before/after SA	1.4	1.3	1.9	-1.4	-0.4	1.3
Ambulatory time before self-admin	2.5	2.6	4.3	-1.3	-2.1	1.4
Ambulatory time after self-admin	0.7	0.7	1.2	0.6	1.1	-0.8
Total heroin consumption	2.7	3.2	4.1	-2.0	-1.4	1.9
Area under the delay curve	1.6	1.7	2.7	-0.9	-1.7	1.3
Delay disc. indifference point, 0s delay	1.2	1.3	2.9	-0.8	-1.7	0.7
Delay disc. indifference point, 16s delay	0.2	0.2	0.2	0.5	0.5	-0.3
Delay disc. indifference point, 2s delay	1.5	1.6	3.8	-0.6	-1.9	0.9
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	0.3	0.3	-0.4
Delay disc. indifference point, 4s delay	1.7	1.8	3.5	-0.8	-1.9	1.2
Delay disc. indifference point, 8s delay	4.0	4.1	4.7	-1.8	-2.2	2.1
Delay discount exponential model param	2.0	2.2	3.4	1.0	1.8	-1.4
Delay discount hyperbolic model param	2.0	2.2	3.6	1.0	1.9	-1.4
Fecal boli incidents, locomotor time 1	0.2	0.2	0.4	0.3	0.7	-0.3
Change in fecal boli incidents, locomotor task	0.0	0.0	0.1	0.1	-0.2	-0.3
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.0	0.1	-0.1	-0.1
Bouts of movement, locomotor time 1	0.0	0.0	0.1	-0.1	0.2	0.2
Total resting periods, locomotor time 1	0.0	0.0	0.1	0.1	0.4	0.1
Rest time, locomotor task time 1	0.4	0.4	0.7	-0.8	-0.1	0.7
Distance moved, locomotor task time 1	0.3	0.4	0.6	0.7	0.2	-0.7
Vertical activity count, locomotor time 1	1.1	1.1	1.6	1.3	0.8	-1.0
Time >=10cm from walls, locomotor time 2	0.6	0.6	0.9	0.8	0.7	-0.9
Bouts of movement, locomotor time 2	0.3	0.3	0.5	-0.6	-0.1	0.7
Total resting periods, locomotor time 2	0.3	0.3	0.5	-0.6	-0.1	0.7
Rest time, locomotor task time 2	1.2	1.4	1.9	-1.3	-0.8	1.4
Distance moved, locomotor task time 2	0.4	0.4	0.8	0.7	0.2	-0.9
Vertical activity count, locomotor time 2	0.1	0.1	0.1	0.2	0.2	-0.3
Weight adjusted by age	0.0	0.0	0.1	-0.1	-0.3	-0.0
Seeking ratio, delayed vs. immediate footshock	0.4	0.4	0.7	0.8	0.3	-0.7
Locomotion in novel chamber	0.6	0.8	1.1	1.0	0.8	-0.8
Locomotion in novel chamber post-restriction	0.1	0.1	0.1	-0.2	0.3	0.2
Progressive ratio	0.1	0.2	0.2	-0.5	0.1	0.5
Food seeking constrained by brief footshock	1.1	1.3	1.4	-1.1	-1.2	1.1
Seeking ratio, punishment vs. effort	0.3	0.4	1.0	-0.3	-1.0	0.2
Run reversals in cocaine runway, females	0.5	0.5	0.6	-0.6	-0.8	0.8
Run reversals in cocaine runway, males	0.3	0.3	0.5	-0.5	0.3	0.7
Latency to leave start box in cocaine runway	0.5	0.5	1.3	0.3	1.1	-0.5
Latency to leave start box in cocaine runway, F	0.9	1.0	1.9	0.6	1.4	-0.9
Latency to leave start box in cocaine runway, M	0.7	0.7	1.4	0.6	1.2	-0.6
Cd content in liver	0.7	0.8	1.3	0.7	1.1	-0.7
Co content in liver	0.7	0.9	1.5	0.8	1.2	-0.7
Cu content in liver	0.0	0.0	0.1	-0.2	-0.3	0.1
Fe content in liver	0.1	0.1	0.2	-0.2	-0.5	0.2
K content in liver	0.1	0.1	0.2	0.5	0.0	-0.5
Mg content in liver	2.7	2.8	3.2	1.7	1.5	-1.8
Mn content in liver	0.5	0.6	0.6	-0.8	-0.8	0.8
Na content in liver	0.1	0.2	0.4	-0.1	-0.7	0.1
Rb content in liver	2.9	3.6	3.8	1.9	1.8	-2.0
Se content in liver	0.6	0.7	1.1	1.0	0.3	-1.0
Sr content in liver	0.0	0.0	0.0	-0.0	0.1	0.2
Zn content in liver	1.2	1.3	2.0	-0.9	-1.4	1.0