Tob2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000050500 0.04 0.02 8.0e-05 0.03 0.03 0.03 0.03 3.0e-04 3.1e-04 3.6e-04 2.3e-04
2 Brain gene expression ENSRNOG00000050500 0.08 0.04 2.3e-08 0.08 0.09 0.07 0.08 8.8e-08 8.1e-09 8.9e-07 6.3e-08
3 Brain mRNA stability ENSRNOG00000050500 0.06 0.04 8.5e-06 0.05 0.05 0.05 0.05 2.6e-05 2.8e-05 1.9e-05 1.5e-05
4 IL gene expression ENSRNOG00000050500 0.22 0.15 2.6e-03 0.04 0.02 0.04 0.02 5.1e-02 1.1e-01 3.2e-02 1.3e-01
5 IL mRNA stability ENSRNOG00000050500 0.19 0.12 4.9e-03 0.06 0.03 0.07 0.06 1.4e-02 6.5e-02 1.1e-02 1.5e-02
6 PL gene expression ENSRNOG00000050500 0.05 0.03 3.1e-04 0.02 0.01 0.01 0.01 9.1e-03 3.7e-02 6.9e-02 5.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
BMI with tail1.44.57.32.1-2.42.2-1.41.6-2.7
BMI without tail0.10.30.60.80.10.60.10.4-0.6
Body weight1.45.97.52.4-2.42.7-2.12.2-2.7
Epididymis fat weight4.410.213.83.5-2.13.2-3.73.6-2.7
Glucose0.20.30.8-0.20.5-0.50.9-0.60.2
Heart weight2.23.24.51.7-2.12.1-1.01.5-2.1
Left kidney weight9.527.333.44.7-5.75.8-4.94.8-5.3
Right kidney weight9.627.337.64.5-6.15.8-4.74.6-5.5
Tail length0.10.31.2-0.21.1-0.30.2-0.00.8
Length with tail0.20.81.20.8-0.61.0-1.11.0-0.6
Length without tail0.81.63.00.8-1.71.3-1.40.9-1.3
Liver weight, left1.11.72.81.4-0.31.4-1.71.7-0.9
Liver weight, right3.96.510.12.8-1.12.5-3.22.9-2.3
Parametrial fat weight0.20.40.60.6-0.70.5-0.50.6-0.7
Retroperitoneal fat weight4.414.417.33.9-3.43.7-4.23.9-3.7
Intraocular pressure0.40.51.10.7-0.40.6-1.00.9-0.4
Extensor digitorum longus weight0.10.30.9-0.30.9-0.30.7-0.50.4
Soleus weight0.71.93.2-1.80.1-1.21.5-1.71.4
Tibialis anterior weight0.62.02.9-1.50.9-1.51.7-1.61.3
Tibia length0.30.82.00.5-1.41.0-0.60.5-0.9
Number of licking bursts1.11.31.8-1.40.7-1.11.1-1.21.3
Food consumed during 24 hour testing period1.21.42.51.1-1.61.1-0.80.7-1.5
Times rat made contact with spout0.30.31.40.0-1.20.4-0.2-0.1-0.4
Mean time between licks in bursts0.50.70.8-0.70.8-0.90.9-0.70.8
Mean num. licks in bursts2.02.42.61.5-1.51.6-1.61.5-1.6
Std. dev. time between licks in bursts2.42.84.5-1.80.8-1.72.1-2.01.4
Water consumed over 24 hours0.30.30.90.2-0.90.7-0.30.0-0.6
Indifference point 0 sec0.71.12.3-1.20.4-0.81.5-1.30.5
Indifference point AUC0.70.91.7-1.30.1-0.80.6-0.91.2
Indifference point function ln k1.52.23.01.7-0.91.6-1.31.4-1.7
Indifference point function log k1.52.23.01.7-0.91.6-1.31.4-1.7
Delay discounting total patch changes 0 sec0.81.32.4-1.30.6-0.91.5-1.40.7
Delay discounting total patch changes 12 sec0.20.30.6-0.8-0.3-0.30.6-0.70.3
Delay discounting total patch changes 18 sec0.60.81.3-1.0-0.1-0.71.2-1.10.6
Delay discounting total patch changes 24 sec0.50.60.9-1.00.4-0.70.7-0.70.9
Delay discounting total patch changes 6 sec1.42.23.7-1.90.1-1.11.9-1.91.1
Delay discounting time to switch 0 sec0.20.30.90.90.40.2-0.40.5-0.7
Delay discounting water rate 0 sec0.40.71.2-1.10.0-0.31.1-1.10.6
Delay discounting water rate 12 sec0.30.50.8-0.70.9-0.40.8-0.70.7
Delay discounting water rate 18 sec2.02.73.5-1.81.3-1.41.7-1.91.6
Delay discounting water rate 24 sec0.00.00.10.0-0.20.30.3-0.2-0.2
Delay discounting water rate 6 sec1.11.62.2-1.31.4-1.01.1-1.11.5
Locomotor activity2.03.24.51.8-1.22.1-1.71.7-2.0
Locomotor testing distance0.00.00.0-0.10.2-0.00.00.0-0.0
Locomotor testing rearing1.52.43.01.6-1.21.7-1.51.7-1.6
Light reinforcement 10.00.00.1-0.20.30.10.2-0.10.2
Light reinforcement 21.21.62.11.5-0.71.2-1.41.4-1.2
Reaction time number correct0.91.32.9-1.01.7-1.10.4-0.61.4
Reaction time mean minus median0.30.40.60.8-0.00.8-0.50.7-0.6
Reaction time mean minus median AUC1.51.92.61.6-0.61.4-1.41.6-1.3
Reaction time num false alarms0.10.20.60.20.80.3-0.20.40.1
Reaction time num false alarms AUC0.10.20.8-0.00.90.2-0.10.30.4
Reaction time trials correct on left0.91.32.9-1.01.7-1.10.4-0.61.4
Reaction time trials on left1.01.43.2-1.01.8-1.20.4-0.61.5
Reaction time mean0.00.00.20.10.4-0.00.20.10.0
Reaction time mean AUC0.00.00.10.00.4-0.10.20.10.1
Median of all reaction times0.10.10.3-0.20.5-0.40.4-0.20.3
Reaction time omissions0.20.30.7-0.50.8-0.50.2-0.30.8
Reaction time false alarm rate0.20.20.50.5-0.10.7-0.30.6-0.4
Reaction time premature initiation rate0.60.81.8-1.00.1-0.51.3-1.20.3
Reaction time premature initiations0.60.91.3-1.10.6-0.81.2-1.10.7
Std. dev. reaction times0.50.71.01.0-0.31.0-0.61.0-0.8
Reaction time trials completed1.01.43.2-1.01.8-1.20.4-0.61.5
Reaction time trials AUC0.71.02.5-0.81.6-1.00.3-0.51.3
Social response proportion0.40.41.30.7-0.50.60.20.3-1.1
Social responses0.10.20.3-0.50.4-0.30.4-0.40.4
Social time1.82.33.1-1.51.2-1.81.6-1.51.5
Conditioned locomotion0.70.81.21.0-0.40.9-1.01.1-0.7
Cocaine response after cond. corrected0.10.10.10.30.00.3-0.30.2-0.3
Cocaine response after cond. not corrected0.10.10.20.40.20.4-0.20.1-0.3
Cocaine response before conditioning0.00.10.1-0.00.3-0.20.4-0.20.1
Saline control response0.20.20.40.50.50.6-0.50.50.0
Condit. Reinf. active minus inactive responses0.50.71.1-1.0-0.6-0.80.8-1.00.6
Condit. Reinf. active-inactive response ratio0.30.40.7-0.6-0.8-0.40.6-0.8-0.0
Condit. Reinf. active responses0.10.20.9-0.4-1.00.00.1-0.3-0.0
Condit. Reinf. inactive responses0.30.40.80.2-0.90.6-0.70.6-0.3
Condit. Reinf. lever presses0.60.81.2-1.00.2-0.81.1-1.10.7
Condit. Reinf. lever reinforcers received0.10.20.6-0.5-0.8-0.20.3-0.40.1
Pavlov. Cond. lever latency1.31.83.41.3-0.81.2-1.81.7-0.9
Pavlov. Cond. magazine entry latency4.04.66.5-2.21.2-2.32.5-2.51.9
Pavlov. Cond. change in total contacts1.62.35.0-1.5-0.2-1.22.2-2.10.5
Pavlov. Cond. index score2.83.75.7-2.01.0-2.02.4-2.31.5
Pavlov. Cond. latency score3.74.67.0-2.31.0-2.22.7-2.61.7
Pavlov. Cond. lever contacts1.11.53.1-1.10.7-1.11.8-1.60.7
Pavlov. Cond. magazine entry number2.22.73.81.8-0.71.8-1.91.9-1.4
Pavlov. Cond. intertrial magazine entries2.22.85.01.5-2.21.6-1.41.5-1.8
Pavlov. Cond. lever-magazine prob. diff.2.73.45.3-1.91.1-1.92.3-2.21.4
Pavlov. Cond. response bias1.52.14.0-1.40.6-1.42.0-1.90.8
Conditioned reinforcement - actives0.10.10.3-0.1-0.50.1-0.20.0-0.0
Conditioned reinforcement - inactives0.81.01.9-1.1-0.3-0.81.4-1.10.7
Conditioned locomotion0.91.12.90.6-1.71.0-0.20.3-1.5
Intermittent access intake day 1-15 change0.50.50.6-0.70.5-0.70.7-0.80.7
Intermittent access intake escalation0.50.50.5-0.70.5-0.70.7-0.70.7
Intermittent access intake escalation 20.10.10.2-0.40.5-0.30.3-0.30.4
Intermitt. access day 1 inactive lever presses0.30.31.0-0.2-1.00.20.6-0.4-0.4
Intermitt. access day 15 inactive lever presses0.60.62.7-0.6-1.6-0.10.7-0.5-0.0
Intermitt. access escalation Index0.60.51.1-0.8-0.2-0.61.0-0.90.4
Intermittent access day 1 total infusions0.50.51.50.6-1.20.6-0.50.6-0.6
Intermittent access day 15 total infusions0.20.20.3-0.5-0.3-0.40.6-0.50.3
Intermittent access terminal intake (last 3 days)0.00.00.10.1-0.30.0-0.10.10.0
Intermittent access total infusions0.10.10.50.3-0.70.2-0.20.2-0.4
Intermittent access day 1 locomotion0.30.30.70.3-0.80.5-0.00.4-0.8
Intermittent access day 15 total locomotion0.10.10.20.3-0.40.3-0.20.2-0.5
Intermittent access total locomotion0.30.40.90.5-0.90.5-0.30.3-0.8
Intermittent access standard deviation0.50.51.00.5-1.00.6-0.40.6-0.9
Cocaine induced anxiety1.41.72.51.3-1.41.1-1.21.1-1.6
Post-drug Anxiety0.20.20.50.2-0.70.4-0.10.0-0.7
Baseline Anxiety1.71.82.0-1.41.4-1.21.3-1.31.4
Lifetime Intake0.40.51.90.3-1.40.3-0.20.2-0.7
Incentive Sensitization - Responses0.70.71.1-1.0-0.1-0.90.8-0.90.9
Incentive Sensitization - Breakpoint0.50.50.8-0.9-0.4-0.70.7-0.80.7
Progressive ratio test 1 active lever presses0.30.31.30.4-1.20.2-0.40.3-0.4
Progressive ratio test 1 breakpoint0.30.30.80.4-0.90.2-0.50.4-0.4
Progressive ratio test 1 inactive lever presses0.40.41.90.5-1.40.20.10.2-0.7
Progressive ratio test 2 active lever presses0.30.40.5-0.7-0.6-0.70.3-0.50.6
Progressive ratio test 2 breakpoint0.20.30.8-0.5-0.9-0.50.3-0.50.3
Progressive ratio test 2 inactive lever presses0.70.81.2-1.0-0.4-1.01.1-0.91.0
Total sessions with >9 infusions0.70.83.30.4-1.80.6-0.30.2-0.9
Short access day 1 total inactive lever presses0.50.61.90.0-1.40.70.4-0.2-0.9
Short access day 10 total inactive lever presses0.20.20.40.3-0.50.6-0.20.4-0.5
Short access day 1 total infusions0.70.73.20.1-1.80.70.00.3-0.8
Short access day 10 total infusions0.80.91.61.0-1.30.7-0.70.6-1.2
Short access total infusions1.31.55.30.7-2.30.8-0.40.6-1.4
Short access day 1 locomotion0.10.10.7-0.0-0.8-0.00.3-0.0-0.3
Short access day 10 total locomotion0.10.10.30.3-0.20.20.30.3-0.6
Short access total locomotion0.90.92.50.6-1.60.7-0.10.5-1.4
Compulsive drug intake3.23.15.0-2.21.4-1.71.5-1.72.0
One hour access (0.3 mA shock)0.20.20.5-0.40.4-0.70.4-0.30.6
One hour access (shock baseline)0.50.61.21.1-0.30.4-0.80.9-0.7
Number of responses in last shaping day1.91.93.6-1.60.0-1.41.9-1.70.9
Context. condit. distance diff. score7.99.711.93.3-2.33.3-3.43.4-2.8
Locomotion velocity, session 10.40.40.9-0.90.4-0.40.3-0.60.9
Locomotion distance, session 13.74.86.7-2.51.8-2.31.7-2.12.6
Locomotion velocity, session 20.10.10.30.3-0.30.5-0.20.1-0.5
Locomotion distance, session 24.26.07.8-2.71.2-2.62.7-2.82.2
Locomotion velocity, session 30.30.41.00.70.10.6-1.00.7-0.3
Locomotion distance, session 31.21.32.8-1.11.3-1.20.4-0.71.7
Stereotopy head waving bouts, day 30.70.81.30.9-0.81.1-0.80.7-1.1
Stereotopy head waving duration, day 33.23.95.82.1-1.52.3-1.71.7-2.4
Locomotion velocity, session 70.30.40.80.7-0.10.3-0.90.8-0.5
Locomotion distance, session 70.10.10.30.0-0.3-0.5-0.20.10.1
Stereotopy head waving bouts, day 72.42.74.21.7-0.62.0-1.81.7-1.5
Stereotopy head waving duration, day 72.73.24.52.0-0.42.1-2.02.0-1.7
Locomotion velocity, session 81.11.32.40.8-1.61.5-0.80.6-1.3
Locomotion distance, session 80.81.21.61.2-0.81.2-1.21.2-0.9
Degree of sensitization distance3.43.45.61.9-2.11.7-1.21.5-2.4
Degree of sensitization stereotypy1.61.72.71.3-0.21.6-1.61.5-1.0
Condit. Reinf. active minus inactive responses0.40.50.7-0.8-0.1-0.90.9-0.80.5
Condit. Reinf. active-inactive response ratio0.10.20.30.3-0.50.4-0.40.4-0.4
Condit. Reinf. active responses1.31.62.3-1.20.7-1.51.5-1.31.1
Condit. Reinf. inactive responses1.82.22.8-1.31.4-1.71.6-1.31.4
Incentive salience index mean0.91.11.7-1.20.1-1.31.2-1.20.9
Condit. Reinf. lever presses1.01.42.2-1.20.5-1.51.4-1.21.0
Time in familiar zone, hab. session 10.20.20.5-0.7-0.1-0.50.1-0.30.7
Time in novel zone, hab. session 11.51.42.51.5-0.31.6-0.71.0-1.5
Total zone transitions, hab. session 14.56.310.1-2.82.2-2.61.9-2.23.2
Total locomotion distance, hab. session 11.82.64.9-1.62.1-1.40.9-1.12.2
Locomotion velocity, hab. session 12.43.45.6-1.82.1-1.71.3-1.52.4
Time in familiar zone, hab. session 20.30.30.70.40.60.2-0.80.70.3
Time in novel zone, hab. session 20.20.20.4-0.3-0.60.20.7-0.5-0.3
Total zone transitions, hab. session 22.93.85.8-2.40.7-1.82.0-2.22.1
Total locomotion distance, hab. session 21.52.02.8-1.60.8-1.31.7-1.61.4
Locomotion velocity, hab. session 22.53.34.1-2.01.2-1.82.0-2.01.8
Novel to familiar place preference ratio2.93.05.31.8-0.92.3-1.71.7-1.7
Novelty place preference3.94.06.72.1-1.12.6-2.12.0-1.9
Time in novel zone, NPP test4.85.08.22.3-1.42.9-2.32.3-2.1
Total zone transitions, NPP test4.76.810.0-3.01.9-2.62.2-2.53.2
Total locomotion distance, NPP test2.12.93.6-1.91.3-1.71.6-1.81.9
Locomotion velocity, NPP test2.73.94.9-2.11.7-2.11.8-1.92.2
Pavlov. Cond. lever latency0.91.21.91.1-0.71.4-1.21.1-0.9
Pavlov. Cond. magazine entry latency1.21.62.4-1.40.3-1.61.4-1.41.1
Pavlov. Cond. change in total contacts2.42.63.9-1.80.2-1.72.0-1.91.2
Pavlov. Cond. index score0.70.91.4-1.0-0.2-1.21.1-1.10.6
Pavlov. Cond. latency score0.50.71.1-0.9-0.2-1.01.0-1.00.5
Pavlov. Cond. lever contacts1.21.42.3-1.20.6-1.51.3-1.21.0
Pavlov. Cond. magazine entry number0.81.01.81.2-0.01.3-1.01.1-1.0
Pavlov. Cond. intertrial magazine entries1.31.52.2-1.30.8-1.11.5-1.41.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.0-1.2-0.0-1.41.1-1.20.8
Pavlov. Cond. response bias1.11.32.4-1.20.1-1.51.2-1.20.9
Bone: apparent density0.20.30.5-0.40.6-0.60.7-0.70.3
Bone surface0.40.61.0-0.90.7-0.50.7-1.00.8
Bone volume0.00.10.1-0.20.4-0.10.2-0.30.3
Bone: connectivity density0.10.10.2-0.20.3-0.30.5-0.50.1
Bone: cortical apparent density0.91.21.7-1.30.6-1.30.9-1.11.2
Bone: cortical area0.91.42.01.1-1.41.3-0.90.9-1.4
Bone: cortical porosity0.91.01.51.2-0.51.0-0.91.0-1.2
Bone: cortical porosity1.82.03.31.6-0.81.5-1.21.2-1.8
Bone: cortical thickness0.20.31.3-0.0-1.10.00.2-0.2-0.6
Bone: cortical thickness0.20.31.4-0.3-1.20.00.3-0.2-0.3
Bone: cortical tissue density0.91.21.6-1.30.6-1.30.9-1.11.2
Bone: elastic displacement0.10.10.20.10.40.4-0.20.1-0.0
Bone: elastic work1.92.54.01.6-1.31.9-1.11.2-2.0
Bone: endosteal estimation0.71.53.11.3-0.21.8-1.21.3-1.1
Bone: endosteal perimeter1.83.75.42.1-0.62.3-2.12.1-1.8
Bone: final force0.91.43.90.7-2.01.0-0.70.5-1.5
Bone: final moment0.91.54.10.7-2.01.2-0.70.5-1.5
Bone: marrow area0.71.63.41.3-0.21.8-1.21.3-1.1
Bone: maximum diameter2.85.17.42.1-2.22.7-1.92.0-2.5
Bone: maximum force1.62.95.91.3-2.41.8-1.11.0-2.1
Bone: maximum moment1.83.16.31.3-2.51.9-1.11.0-2.1
Bone: minimum diameter0.51.01.51.1-0.41.2-1.01.1-0.9
Bone: periosteal estimation1.22.44.21.6-0.92.0-1.41.4-1.6
Bone: periosteal perimeter3.25.37.02.4-1.52.7-2.32.4-2.4
Bone: post-yield work0.20.30.8-0.4-0.9-0.00.6-0.5-0.2
Bone: stiffness1.11.73.31.1-1.81.3-0.70.8-1.7
Bone: tissue strength0.00.00.1-0.0-0.30.2-0.0-0.1-0.2
Bone: trabecular number0.10.20.40.50.30.2-0.60.5-0.2
Bone: trabecular spacing0.50.62.10.4-1.40.6-0.30.4-0.9
Bone: trabecular thickness0.10.10.30.30.5-0.00.00.20.0
Bone: trabecular tissue density1.21.62.8-1.21.0-1.11.7-1.50.9
Breakpoint value in progressive ratio session0.10.10.3-0.2-0.0-0.10.6-0.3-0.3
Distance traveled before self-admin0.30.30.5-0.6-0.7-0.70.4-0.10.5
Distance traveled after self-admin0.90.92.2-1.1-0.6-0.41.5-1.30.2
Delta time in closed arm before/after self-admin0.70.72.50.1-1.60.6-0.60.6-0.8
Delta time in open arm before/after self-admin0.30.31.00.81.00.00.00.1-0.2
Diff in mean of infusions in LGA sessions0.60.71.3-1.10.1-0.90.6-0.90.7
Extinction: sum of active levers before priming0.00.00.1-0.2-0.2-0.00.3-0.1-0.1
Active lever presses in extinction session 60.30.20.70.5-0.50.4-0.20.2-0.8
Delta distance traveled before/after self-admin0.20.20.4-0.3-0.10.50.4-0.6-0.2
Delta ambulatory time before/after self-admin0.30.30.8-0.5-0.20.50.6-0.9-0.2
Time in closed arm before self-admin4.45.06.9-1.92.3-2.22.6-2.31.9
Time in closed arm after self-admin0.30.30.60.3-0.70.5-0.20.4-0.7
Time in open arm before self-admin0.30.31.20.20.10.4-1.10.80.1
Time in open arm after self-admin0.50.51.50.91.20.2-0.60.6-0.3
Sum of active levers in priming session hrs 5-60.00.00.00.10.10.00.00.0-0.1
Time to tail flick, vehicle, before self-admin0.10.10.2-0.20.20.1-0.1-0.10.4
Time to tail flick, vehicle, after self-admin0.60.73.3-0.31.8-0.40.0-0.20.8
Time to tail flick, test, before self-admin0.30.30.80.20.20.2-0.90.70.4
Time to tail flick, test, after self-admin1.11.11.5-1.01.2-1.11.0-1.01.0
Delta time to tail flick, vehicle, before/after SA0.10.10.10.30.40.00.10.1-0.4
Delta time to tail flick, test, before/after SA3.02.73.7-1.61.5-1.61.9-1.81.4
Ambulatory time before self-admin0.50.50.8-0.9-0.5-0.80.7-0.30.9
Ambulatory time after self-admin2.32.64.4-2.00.4-1.12.1-2.01.2
Total heroin consumption0.10.20.5-0.7-0.5-0.20.4-0.40.0
Area under the delay curve0.50.51.0-0.80.1-1.00.5-0.70.9
Delay disc. indifference point, 0s delay1.21.32.11.4-1.01.0-0.81.2-1.3
Delay disc. indifference point, 16s delay2.02.12.8-1.41.0-1.61.2-1.61.7
Delay disc. indifference point, 2s delay0.10.10.30.0-0.6-0.2-0.10.0-0.0
Delay disc. indifference point, 24s delay0.80.81.4-1.00.4-1.00.2-1.01.2
Delay disc. indifference point, 4s delay0.50.50.9-0.8-0.6-0.70.9-0.90.5
Delay disc. indifference point, 8s delay1.01.01.9-1.10.6-1.40.8-0.91.2
Delay discount exponential model param0.60.71.20.9-0.21.1-0.60.8-1.0
Delay discount hyperbolic model param0.40.50.80.70.00.9-0.50.7-0.8
Fecal boli incidents, locomotor time 10.40.40.8-0.60.4-0.70.6-0.90.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.3-0.20.3-0.50.30.1
Time >=10cm from walls, locomotor time 10.10.10.20.1-0.30.1-0.20.1-0.4
Bouts of movement, locomotor time 10.70.81.70.9-0.60.6-1.30.9-0.7
Total resting periods, locomotor time 10.30.30.60.6-0.60.2-0.80.5-0.5
Rest time, locomotor task time 10.40.41.20.5-1.10.2-0.30.2-0.9
Distance moved, locomotor task time 10.70.81.20.9-0.31.0-1.01.1-0.7
Vertical activity count, locomotor time 10.00.00.10.10.10.2-0.00.2-0.1
Time >=10cm from walls, locomotor time 20.40.40.7-0.70.4-0.70.8-0.80.3
Bouts of movement, locomotor time 20.40.41.00.4-1.00.4-0.20.4-1.0
Total resting periods, locomotor time 20.30.30.90.2-1.00.2-0.00.2-0.8
Rest time, locomotor task time 20.30.40.6-0.60.0-0.70.6-0.80.6
Distance moved, locomotor task time 21.11.31.91.3-0.61.1-1.11.4-1.1
Vertical activity count, locomotor time 20.50.50.70.7-0.40.9-0.60.8-0.8
Weight adjusted by age0.10.10.2-0.50.4-0.2-0.0-0.30.4
Seeking ratio, delayed vs. immediate footshock3.03.44.9-1.71.5-2.22.0-1.91.6
Locomotion in novel chamber0.81.03.2-1.01.8-0.51.0-0.50.9
Locomotion in novel chamber post-restriction0.60.71.3-1.01.1-1.00.5-0.40.9
Progressive ratio0.00.00.10.10.1-0.20.3-0.20.2
Food seeking constrained by brief footshock1.01.21.91.0-1.41.0-0.91.0-1.2
Seeking ratio, punishment vs. effort0.30.40.90.3-1.00.5-0.50.5-0.7
Run reversals in cocaine runway, females0.80.81.5-0.81.2-0.80.5-0.51.1
Run reversals in cocaine runway, males0.60.61.50.4-0.30.8-1.20.9-0.1
Latency to leave start box in cocaine runway1.01.11.41.2-0.51.0-1.21.1-1.1
Latency to leave start box in cocaine runway, F0.10.10.30.00.6-0.10.0-0.00.2
Latency to leave start box in cocaine runway, M3.93.74.62.1-1.71.9-1.91.9-2.1
Cd content in liver0.70.81.30.7-0.61.1-1.01.0-0.6
Co content in liver0.20.20.70.1-0.80.50.10.0-0.5
Cu content in liver3.54.25.1-2.02.1-2.32.0-1.92.1
Fe content in liver0.20.20.50.50.30.7-0.10.5-0.3
K content in liver1.31.31.9-1.40.3-1.01.4-1.40.9
Mg content in liver2.02.03.2-1.60.4-1.51.8-1.81.0
Mn content in liver0.10.10.20.1-0.20.1-0.50.30.1
Na content in liver2.22.42.7-1.51.6-1.71.5-1.41.6
Rb content in liver0.10.20.3-0.5-0.2-0.40.4-0.50.4
Se content in liver0.50.61.3-0.71.1-0.70.4-0.51.0
Sr content in liver0.50.40.7-0.60.8-0.80.4-0.40.8
Zn content in liver1.31.41.8-1.31.3-1.21.1-1.11.3