# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | gene expression | ENSRNOG00000050233 | 0.420 | 0.1200 | 0.0e+00 | 0.430 | 0.389 | 0.432 | 0.437 | 5.2e-52 | 9.5e-46 | 3.1e-52 | 4.0e-53 |
2 | BLA | gene expression | ENSRNOG00000050233 | 0.904 | 0.0395 | 0.0e+00 | 0.661 | 0.624 | 0.669 | 0.666 | 3.3e-46 | 4.9e-42 | 3.2e-47 | 7.9e-47 |
3 | BLA | intron excision ratio | chr20:3217297:3217547 | 0.060 | 0.0380 | 3.8e-03 | 0.007 | 0.014 | 0.005 | 0.007 | 1.2e-01 | 5.3e-02 | 1.6e-01 | 1.3e-01 |
4 | BLA | intron excision ratio | chr20:3217362:3217547 | 0.088 | 0.0610 | 2.4e-03 | 0.063 | 0.033 | 0.048 | 0.039 | 2.8e-04 | 7.3e-03 | 1.3e-03 | 3.6e-03 |
5 | Brain | gene expression | ENSRNOG00000050233 | 0.750 | 0.0640 | 0.0e+00 | 0.616 | 0.654 | 0.673 | 0.677 | 2.7e-72 | 6.7e-80 | 6.0e-84 | 6.3e-85 |
6 | Brain | mRNA stability | ENSRNOG00000050233 | 0.282 | 0.0996 | 0.0e+00 | 0.269 | 0.262 | 0.258 | 0.271 | 6.2e-25 | 3.1e-24 | 6.9e-24 | 4.0e-25 |
7 | IL | gene expression | ENSRNOG00000050233 | 0.777 | 0.0850 | 0.0e+00 | 0.456 | 0.488 | 0.488 | 0.484 | 2.1e-12 | 1.8e-13 | 1.8e-13 | 2.4e-13 |
8 | LHb | gene expression | ENSRNOG00000050233 | 0.626 | 0.1259 | 5.6e-12 | 0.418 | 0.370 | 0.386 | 0.413 | 4.3e-11 | 1.1e-09 | 3.7e-10 | 5.9e-11 |
9 | Liver | gene expression | ENSRNOG00000050233 | 0.120 | 0.0620 | 1.0e-08 | 0.082 | 0.074 | 0.086 | 0.083 | 2.0e-09 | 1.2e-08 | 8.2e-10 | 1.6e-09 |
10 | NAcc | gene expression | ENSRNOG00000050233 | 0.765 | 0.0950 | 5.6e-17 | 0.576 | 0.562 | 0.480 | 0.521 | 1.2e-15 | 4.0e-15 | 2.5e-12 | 1.2e-13 |
11 | NAcc2 | gene expression | ENSRNOG00000050233 | 0.650 | 0.0890 | 0.0e+00 | 0.475 | 0.457 | 0.486 | 0.493 | 1.4e-28 | 3.5e-27 | 1.8e-29 | 4.6e-30 |
12 | OFC | alternative TSS | ENSRNOT00000074049 | 0.174 | 0.1130 | 7.7e-03 | 0.092 | 0.060 | 0.079 | 0.096 | 3.4e-03 | 1.5e-02 | 6.5e-03 | 2.9e-03 |
13 | OFC | alternative TSS | ENSRNOT00000084918 | 0.173 | 0.1130 | 8.3e-03 | 0.084 | 0.058 | 0.076 | 0.089 | 5.1e-03 | 1.7e-02 | 7.3e-03 | 3.9e-03 |
14 | OFC | gene expression | ENSRNOG00000050233 | 0.875 | 0.0476 | 0.0e+00 | 0.533 | 0.477 | 0.399 | 0.417 | 6.2e-15 | 5.9e-13 | 1.5e-10 | 4.6e-11 |
15 | PL | gene expression | ENSRNOG00000050233 | 0.769 | 0.0859 | 0.0e+00 | 0.632 | 0.629 | 0.644 | 0.662 | 4.8e-19 | 7.0e-19 | 1.2e-19 | 1.6e-20 |
16 | PL2 | gene expression | ENSRNOG00000050233 | 0.790 | 0.0530 | 0.0e+00 | 0.670 | 0.699 | 0.701 | 0.708 | 4.0e-48 | 6.1e-52 | 3.7e-52 | 3.6e-53 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dissection: UMAP 1 of all traits | 3.9 | 14.2 | 19.0 | 3.7 | -4.3 | -4.4 | -3.7 | -4.1 | 4.3 | -3.2 | -3.7 | -0.1 | -4.3 | -4.3 | 4.3 | 0.0 | -4.3 | -3.2 | -4.2 |
retroperitoneal_fat_g | 0.3 | 1.0 | 2.0 | -1.2 | 1.0 | 1.4 | 1.2 | 1.1 | -1.1 | 0.7 | 0.6 | -0.3 | 1.2 | 1.1 | -1.2 | 0.0 | 1.2 | 0.6 | 1.0 |
body_g | 6.1 | 25.7 | 33.7 | -4.9 | 5.8 | 5.7 | 4.9 | 5.7 | -5.8 | 4.6 | 4.9 | 0.7 | 5.7 | 5.7 | -5.7 | 0.0 | 5.8 | 4.5 | 5.8 |
dissection: UMAP 3 of all traits | 4.5 | 12.5 | 18.3 | 2.9 | -4.0 | -3.3 | -3.1 | -4.0 | 3.8 | -4.1 | -3.7 | -1.8 | -3.8 | -4.0 | 3.9 | 0.0 | -3.9 | -3.5 | -4.3 |
kidney_right_g | 3.2 | 9.1 | 13.3 | -2.7 | 3.5 | 3.3 | 2.7 | 3.4 | -3.6 | 2.8 | 2.7 | 0.9 | 3.5 | 3.5 | -3.4 | 0.0 | 3.4 | 2.4 | 3.6 |
dissection: PC 3 of all traits | 2.1 | 5.1 | 9.7 | 2.4 | -2.4 | -1.7 | -1.8 | -2.7 | 2.3 | -3.1 | -2.0 | -1.3 | -2.3 | -2.3 | 2.3 | 0.0 | -2.4 | -2.6 | -2.8 |
dissection: PC 2 of all traits | 0.4 | 1.0 | 2.9 | -0.1 | 1.1 | 0.5 | 0.5 | 1.2 | -0.8 | 1.7 | 0.9 | 1.4 | 0.9 | 1.0 | -1.0 | 0.0 | 1.0 | 1.0 | 1.5 |
glucose_mg_dl | 1.1 | 1.6 | 18.1 | 1.4 | -0.3 | -1.2 | -0.5 | 0.1 | 0.5 | 1.3 | -0.6 | 4.2 | -0.6 | -0.4 | 0.6 | 0.0 | -0.6 | 0.6 | 0.7 |
heart_g | 0.3 | 0.4 | 1.1 | -0.9 | 0.4 | 0.6 | 1.1 | 0.5 | -0.4 | 0.7 | 0.7 | 0.6 | 0.5 | 0.4 | -0.4 | 0.0 | 0.2 | 0.9 | 0.5 |
os_mean | 0.5 | 0.7 | 1.9 | 0.7 | -0.8 | -0.4 | -0.5 | -0.9 | 0.8 | -1.2 | -1.3 | -0.6 | -0.6 | -0.8 | 0.8 | 0.0 | -0.8 | -1.4 | -0.7 |
EDL weight in grams | 0.1 | 0.5 | 3.7 | 0.0 | 0.5 | 0.3 | 0.4 | 0.6 | -0.4 | 1.0 | 0.2 | 1.9 | 0.4 | 0.5 | -0.4 | 0.0 | 0.4 | 0.7 | 0.9 |
Tibia length in mm | 2.9 | 8.3 | 13.2 | -2.2 | 3.1 | 2.8 | 2.6 | 3.3 | -2.9 | 3.6 | 2.7 | 2.8 | 2.9 | 2.9 | -2.9 | 0.0 | 2.9 | 3.2 | 3.6 |
sol weight in grams | 1.0 | 3.0 | 15.3 | -0.1 | 1.3 | 0.3 | 1.1 | 1.7 | -1.0 | 3.1 | 0.9 | 3.9 | 0.9 | 1.2 | -0.9 | 0.0 | 0.9 | 2.4 | 2.3 |
TA weight in grams | 0.0 | 0.1 | 0.7 | -0.3 | -0.2 | 0.2 | 0.0 | -0.3 | -0.1 | -0.7 | -0.4 | -0.8 | 0.0 | -0.0 | 0.1 | 0.0 | -0.0 | -0.5 | -0.5 |
Average time between licks in bursts | 0.4 | 0.5 | 4.8 | 0.7 | 0.2 | -0.6 | -0.4 | 0.3 | 0.0 | 1.2 | -0.1 | 2.2 | -0.0 | 0.1 | 0.1 | 0.0 | 0.0 | 0.6 | 0.8 |
Std. dev. time between licks in bursts | 0.8 | 0.9 | 6.2 | 0.1 | 0.5 | -0.2 | 0.4 | 0.8 | -0.3 | 1.8 | 0.7 | 2.5 | 0.3 | 0.5 | -0.3 | 0.0 | 0.4 | 1.5 | 1.1 |
Number of licking bursts | 0.2 | 0.2 | 1.1 | 0.6 | -0.3 | -0.8 | -0.4 | -0.1 | 0.4 | 0.5 | -0.0 | 1.1 | -0.4 | -0.3 | 0.5 | 0.0 | -0.4 | 0.4 | 0.0 |
Food consumed during 24 hour testing period | 0.8 | 1.0 | 2.3 | -0.3 | 1.2 | 0.9 | 0.6 | 1.2 | -1.1 | 1.3 | 0.6 | 0.5 | 1.1 | 1.1 | -1.1 | 0.0 | 1.1 | 0.6 | 1.5 |
Water consumed over 24 hour session | 0.1 | 0.1 | 0.2 | 0.1 | 0.1 | -0.1 | 0.1 | 0.2 | -0.1 | 0.5 | 0.4 | 0.5 | 0.1 | 0.1 | -0.0 | 0.0 | 0.0 | 0.4 | 0.3 |
Times rat made contact with spout | 2.1 | 2.4 | 5.3 | 0.6 | -1.5 | -1.1 | -1.4 | -1.6 | 1.4 | -2.1 | -1.6 | -2.3 | -1.4 | -1.4 | 1.3 | 0.0 | -1.3 | -2.1 | -1.9 |
Average drop size | 8.8 | 10.7 | 18.5 | -2.3 | 3.3 | 2.4 | 2.9 | 3.6 | -3.1 | 4.3 | 3.7 | 4.0 | 3.1 | 3.2 | -3.0 | 0.0 | 3.1 | 4.2 | 3.8 |
light_reinforcement_lr_relactive | 0.6 | 0.8 | 1.5 | -0.4 | 1.0 | 0.9 | 0.6 | 1.1 | -1.0 | 0.9 | 0.2 | -0.6 | 1.2 | 0.9 | -1.1 | 0.0 | 1.0 | 0.6 | 1.1 |
light_reinforcement_lr_active | 0.1 | 0.1 | 0.8 | -0.1 | 0.1 | 0.5 | 0.3 | 0.1 | -0.0 | -0.1 | 0.2 | -0.9 | 0.4 | 0.2 | -0.3 | 0.0 | 0.2 | 0.0 | -0.2 |
Delay discounting water rate 0 sec | 0.3 | 0.5 | 1.0 | -0.7 | 0.8 | 0.8 | 0.5 | 0.9 | -0.9 | 1.0 | 0.7 | -0.2 | 0.9 | 0.8 | -0.8 | 0.0 | 0.7 | 0.7 | 0.7 |
Median of all reaction times | 0.4 | 0.5 | 2.2 | 1.5 | -0.4 | -0.9 | -0.8 | -0.2 | 0.6 | 0.4 | -0.9 | 1.3 | -0.6 | -0.5 | 0.5 | 0.0 | -0.6 | -0.2 | 0.3 |
locomotor_testing_activity | 1.4 | 2.2 | 5.2 | -1.4 | 1.8 | 1.2 | 1.6 | 1.6 | -1.4 | 1.8 | 1.2 | 0.9 | 1.5 | 1.6 | -1.4 | 0.0 | 1.4 | 1.5 | 2.3 |
reaction_time_corr | 0.2 | 0.2 | 1.0 | -0.6 | -0.0 | 0.8 | 0.9 | -0.2 | -0.3 | -0.5 | 0.2 | -1.0 | 0.1 | -0.1 | -0.2 | 0.0 | -0.0 | -0.2 | -0.4 |
reaction_time_leftcorr | 0.2 | 0.2 | 1.0 | -0.6 | -0.0 | 0.8 | 0.9 | -0.2 | -0.3 | -0.5 | 0.2 | -1.0 | 0.1 | -0.1 | -0.2 | 0.0 | -0.0 | -0.2 | -0.4 |
delay_discounting_pc1800 | 0.6 | 0.8 | 9.1 | -0.5 | -0.1 | 0.6 | 0.0 | -0.5 | -0.0 | -1.3 | 0.1 | -3.0 | -0.1 | 0.0 | -0.1 | 0.0 | 0.1 | -0.7 | -0.8 |
reaction_time_falsealarm | 0.4 | 0.6 | 1.3 | -0.5 | 0.8 | 0.3 | 0.1 | 0.9 | -0.8 | 1.2 | 0.5 | 0.7 | 1.0 | 0.8 | -0.8 | 0.0 | 0.6 | 1.0 | 0.8 |
social_reinforcement_socialrfq | 0.4 | 0.4 | 2.4 | -0.5 | 0.3 | 0.5 | 1.0 | 0.6 | -0.1 | 1.0 | 0.8 | 1.5 | 0.1 | 0.2 | -0.4 | 0.0 | 0.3 | 0.8 | 0.6 |
reaction_time_pinit | 1.5 | 2.1 | 3.6 | -1.7 | 1.6 | 1.9 | 1.9 | 1.5 | -1.6 | 1.1 | 1.4 | 0.2 | 1.6 | 1.6 | -1.7 | 0.0 | 1.6 | 1.3 | 1.2 |
reaction_time_pinit_slope | 1.3 | 1.7 | 2.8 | 1.7 | -1.3 | -1.4 | -1.4 | -1.5 | 1.4 | -1.1 | -1.4 | -0.3 | -1.4 | -1.3 | 1.6 | 0.0 | -1.6 | -1.3 | -1.1 |
reaction_time_peropfalsealarm_slope | 0.5 | 0.6 | 1.1 | 0.5 | -1.0 | -0.5 | -0.6 | -0.8 | 1.1 | -1.0 | -0.8 | -0.6 | -0.8 | -1.1 | 0.6 | 0.0 | -0.5 | -0.9 | -0.9 |
soc_socialavgti | 0.4 | 0.5 | 2.7 | 1.3 | -0.2 | -1.2 | -1.2 | -0.2 | 0.5 | 0.5 | -0.2 | 1.7 | -0.4 | -0.3 | 0.4 | 0.0 | -0.4 | 0.2 | 0.2 |
reaction_time_peropinit_slope | 0.4 | 0.4 | 0.8 | 0.9 | -0.6 | -0.7 | -0.7 | -0.8 | 0.7 | -0.6 | -0.3 | 0.3 | -0.6 | -0.6 | 0.7 | 0.0 | -0.7 | -0.7 | -0.5 |
reaction_time_meanrt_slope | 0.7 | 0.9 | 1.9 | -0.7 | 1.0 | 1.0 | 1.2 | 0.8 | -1.1 | 0.9 | 1.4 | -0.1 | 0.9 | 1.0 | -0.7 | 0.0 | 0.7 | 1.0 | 1.2 |
reaction_time_devmedrt_slope | 0.1 | 0.1 | 0.6 | 0.0 | 0.1 | 0.4 | 0.4 | -0.1 | -0.2 | -0.1 | -0.0 | -0.8 | 0.1 | 0.1 | 0.1 | 0.0 | -0.1 | -0.2 | 0.3 |
pavca_ny_levercs_d4d5 | 0.3 | 0.4 | 1.5 | 0.0 | -0.4 | -0.2 | -0.5 | -0.7 | 0.3 | -1.0 | -0.6 | -1.2 | -0.4 | -0.4 | 0.4 | 0.0 | -0.5 | -0.9 | -0.6 |
pavca_ny_d2_magazine_cs | 1.6 | 1.8 | 3.2 | -1.6 | 1.3 | 1.0 | 1.5 | 1.5 | -1.3 | 1.8 | 1.6 | 1.2 | 1.3 | 1.3 | -1.2 | 0.0 | 1.3 | 1.6 | 1.4 |
ccp_trial_3_saline_dist_mm | 0.7 | 0.9 | 8.4 | -0.9 | 0.0 | 0.9 | 0.4 | -0.3 | -0.1 | -1.3 | -0.5 | -2.9 | 0.1 | 0.1 | -0.1 | 0.0 | 0.2 | -1.1 | -0.5 |
pavca_ny_d5_magazine_ncs | 1.9 | 2.4 | 3.9 | 1.7 | -1.8 | -2.0 | -0.7 | -1.5 | 1.9 | -0.7 | -1.8 | 1.5 | -1.8 | -1.8 | 1.8 | 0.0 | -1.9 | -1.1 | -1.3 |
ccp_change_in_locomotor_activity | 0.8 | 0.9 | 1.6 | -0.6 | 1.1 | 0.9 | 0.8 | 1.2 | -1.0 | 1.2 | 0.6 | 0.7 | 1.0 | 1.1 | -1.1 | 0.0 | 1.0 | 0.9 | 1.3 |
Conditioned locomotion | 0.1 | 0.1 | 0.4 | -0.1 | 0.1 | 0.2 | 0.5 | 0.3 | -0.0 | 0.3 | 0.2 | 0.6 | 0.2 | 0.0 | -0.3 | 0.0 | 0.3 | 0.4 | 0.2 |
Total sessions with >9 infusions | 0.1 | 0.1 | 0.9 | -0.3 | 0.2 | 0.1 | 0.1 | 0.2 | -0.0 | 0.2 | 0.1 | 0.9 | 0.1 | 0.4 | -0.3 | 0.0 | 0.3 | 0.3 | 0.2 |
Velocity during novelty place preference test | 2.2 | 3.2 | 4.9 | 2.2 | -2.0 | -1.8 | -1.7 | -2.0 | 1.9 | -1.8 | -1.9 | -0.7 | -1.9 | -1.9 | 1.9 | 0.0 | -1.9 | -1.9 | -1.9 |
crf_mi_active_responses | 1.4 | 1.8 | 3.3 | 1.2 | -1.4 | -1.3 | -1.0 | -1.5 | 1.4 | -1.4 | -1.8 | 0.1 | -1.4 | -1.4 | 1.4 | 0.0 | -1.3 | -1.7 | -1.4 |
pavca_mi_d1_avg_mag_lat | 2.0 | 2.4 | 6.2 | 2.5 | -1.5 | -1.9 | -2.0 | -1.4 | 1.7 | -0.5 | -1.5 | 1.2 | -1.7 | -1.6 | 1.7 | 0.0 | -1.8 | -1.1 | -0.7 |
pavca_mi_d3_magazine_ncs | 0.9 | 0.9 | 8.7 | -0.9 | 0.2 | 1.3 | 1.0 | 0.0 | -0.5 | -0.9 | 0.2 | -3.0 | 0.5 | 0.4 | -0.5 | 0.0 | 0.5 | -0.3 | -0.3 |
pavca_mi_d1_prob_lev | 2.0 | 2.8 | 6.5 | 2.5 | -1.6 | -2.1 | -2.3 | -1.5 | 1.7 | -0.8 | -2.0 | 1.1 | -1.7 | -1.7 | 1.7 | 0.0 | -1.7 | -1.6 | -1.2 |
pavca_mi_d1_avg_lev_lat | 1.7 | 2.6 | 6.5 | -2.5 | 1.6 | 2.0 | 1.9 | 1.4 | -1.7 | 0.7 | 1.8 | -1.1 | 1.7 | 1.7 | -1.7 | 0.0 | 1.7 | 1.4 | 1.1 |
pavca_mi_d3_prob_mag | 3.1 | 4.0 | 7.8 | -2.8 | 1.9 | 2.7 | 2.8 | 1.7 | -2.1 | 0.8 | 2.2 | -1.9 | 2.1 | 2.0 | -2.1 | 0.0 | 2.1 | 1.6 | 1.3 |
Total cortical area | 0.8 | 1.5 | 10.6 | -0.2 | -0.6 | -0.1 | -1.4 | -0.9 | 0.2 | -2.2 | -0.2 | -3.3 | -0.2 | -0.4 | 0.2 | 0.0 | -0.2 | -1.3 | -1.7 |
tb_th_sd | 3.1 | 3.7 | 6.5 | 1.9 | -1.8 | -1.8 | -2.4 | -2.1 | 1.8 | -2.6 | -2.0 | -1.5 | -1.8 | -1.8 | 1.8 | 0.0 | -1.8 | -2.4 | -2.2 |
Cortical porosity | 0.5 | 0.5 | 1.8 | -1.4 | 0.6 | 0.5 | 0.4 | 0.7 | -0.7 | 0.5 | 1.0 | -0.4 | 0.7 | 0.7 | -0.8 | 0.0 | 0.7 | 0.7 | 0.3 |
length | 9.0 | 17.9 | 23.5 | -4.0 | 4.8 | 4.4 | 3.0 | 4.8 | -4.8 | 4.4 | 4.3 | 1.4 | 4.7 | 4.8 | -4.8 | 0.0 | 4.8 | 4.5 | 4.7 |
Trabecular tissue density | 1.7 | 2.3 | 3.5 | -1.9 | 1.7 | 1.3 | 0.9 | 1.7 | -1.8 | 1.5 | 1.8 | 0.6 | 1.8 | 1.7 | -1.7 | 0.0 | 1.7 | 1.7 | 1.4 |
ctth_sd | 0.2 | 0.2 | 1.7 | 0.2 | 0.3 | -0.3 | -1.3 | 0.3 | -0.4 | 0.2 | 0.1 | 0.2 | 0.3 | 0.4 | -0.4 | 0.0 | 0.4 | 0.3 | 0.1 |
tautz: manual_spc7 | 0.2 | 0.3 | 2.8 | 0.9 | -0.3 | -0.7 | -1.7 | -0.2 | 0.3 | 0.2 | -0.5 | 0.3 | -0.3 | -0.3 | 0.3 | 0.0 | -0.3 | -0.1 | -0.1 |
tautz: manual_mpc15 | 0.2 | 0.3 | 0.5 | 0.4 | -0.5 | -0.5 | -0.5 | -0.6 | 0.4 | -0.7 | -0.5 | -0.6 | -0.4 | -0.4 | 0.4 | 0.0 | -0.4 | -0.7 | -0.6 |
tautz: manual_mpc18 | 2.6 | 3.6 | 6.4 | 2.5 | -2.0 | -2.2 | -2.2 | -1.9 | 2.1 | -1.3 | -2.0 | 0.6 | -2.1 | -2.1 | 2.1 | 0.0 | -2.1 | -1.6 | -1.6 |
tautz: manual_spc15 | 1.5 | 2.2 | 3.5 | 1.8 | -1.5 | -1.9 | -1.6 | -1.5 | 1.8 | -0.9 | -1.6 | -0.0 | -1.7 | -1.6 | 1.7 | 0.0 | -1.8 | -1.3 | -1.2 |
tautz: manual_spc21 | 0.2 | 0.2 | 1.1 | -0.0 | -0.4 | -0.2 | -0.2 | -0.4 | 0.3 | -0.7 | 0.0 | -1.0 | -0.3 | -0.3 | 0.3 | 0.0 | -0.3 | -0.4 | -0.7 |
tautz: manual_spc9 | 0.1 | 0.2 | 1.0 | 0.3 | -0.3 | 0.0 | 0.8 | -0.4 | 0.4 | -0.3 | -0.6 | -1.0 | -0.4 | -0.3 | 0.4 | 0.0 | -0.4 | -0.6 | -0.2 |
tautz: manual_mpc3 | 0.3 | 0.4 | 2.3 | -0.4 | 0.5 | -0.0 | 0.2 | 0.6 | -0.4 | 1.0 | 0.8 | 1.5 | 0.4 | 0.4 | -0.4 | 0.0 | 0.3 | 0.7 | 0.8 |
tautz: manual_spc12 | 1.6 | 2.2 | 3.6 | -1.2 | 1.5 | 1.4 | 1.7 | 1.5 | -1.3 | 1.8 | 1.6 | 1.9 | 1.3 | 1.4 | -1.3 | 0.0 | 1.3 | 1.8 | 1.7 |
tautz: manual_spc14 | 1.0 | 1.5 | 2.9 | -1.5 | 1.2 | 1.2 | 1.7 | 1.3 | -1.1 | 1.4 | 1.0 | -0.6 | 1.1 | 1.1 | -1.1 | 0.0 | 1.1 | 1.3 | 1.4 |
tautz: manual_spc8 | 1.6 | 2.2 | 3.7 | 1.3 | -1.7 | -1.6 | -1.2 | -1.6 | 1.7 | -1.2 | -1.9 | 0.2 | -1.7 | -1.7 | 1.7 | 0.0 | -1.7 | -1.7 | -1.5 |
tautz: manual_mpc7 | 0.4 | 0.4 | 2.6 | -1.1 | 0.4 | 0.9 | 1.6 | 0.5 | -0.4 | 0.5 | 0.5 | 0.0 | 0.4 | 0.4 | -0.4 | 0.0 | 0.4 | 0.5 | 0.6 |
tautz: manual_mpc16 | 6.7 | 9.1 | 12.8 | -3.6 | 3.3 | 3.3 | 2.0 | 3.3 | -3.4 | 2.6 | 3.6 | -0.6 | 3.4 | 3.4 | -3.4 | 0.0 | 3.4 | 3.1 | 2.8 |
tautz: manual_mpc4 | 0.1 | 0.1 | 0.9 | 0.7 | -0.1 | -0.1 | -1.0 | -0.2 | -0.0 | -0.6 | -0.1 | -0.6 | 0.0 | -0.1 | 0.0 | 0.0 | -0.0 | -0.3 | -0.4 |
tautz: manual_mpc10 | 0.9 | 1.3 | 3.2 | -0.3 | -1.2 | -0.1 | 1.2 | -1.3 | 1.0 | -1.8 | -1.3 | -1.1 | -1.0 | -1.0 | 1.0 | 0.0 | -1.0 | -1.8 | -1.4 |
tautz: manual_mpc5 | 0.1 | 0.1 | 0.5 | 0.1 | -0.1 | 0.0 | 0.6 | -0.1 | 0.2 | 0.2 | 0.1 | 0.7 | -0.2 | -0.2 | 0.2 | 0.0 | -0.2 | 0.2 | 0.2 |
tautz: manual_spc22 | 0.2 | 0.2 | 1.3 | -0.3 | 0.5 | 0.6 | 0.0 | 0.3 | -0.6 | -0.2 | 0.4 | -1.1 | 0.6 | 0.5 | -0.6 | 0.0 | 0.6 | 0.0 | 0.2 |
tautz: manual_mpc14 | 0.0 | 0.1 | 0.5 | -0.3 | 0.0 | 0.0 | 0.4 | 0.1 | 0.0 | 0.2 | 0.1 | 0.7 | 0.0 | 0.0 | -0.0 | 0.0 | 0.0 | 0.1 | 0.1 |
tautz: manual_mpc12 | 0.9 | 1.4 | 2.1 | -1.2 | 1.3 | 0.9 | 0.4 | 1.4 | -1.3 | 1.5 | 1.3 | 0.2 | 1.3 | 1.3 | -1.3 | 0.0 | 1.3 | 1.5 | 1.1 |
tautz: manual_mcs | 0.1 | 0.1 | 0.7 | 0.7 | -0.2 | -0.3 | -0.8 | -0.1 | 0.2 | -0.1 | 0.0 | 0.2 | -0.2 | -0.2 | 0.2 | 0.0 | -0.2 | -0.0 | -0.2 |
tautz: manual_spc17 | 2.9 | 3.9 | 9.2 | -1.4 | 1.9 | 1.6 | 2.2 | 2.0 | -1.7 | 2.6 | 2.0 | 3.0 | 1.7 | 1.8 | -1.7 | 0.0 | 1.7 | 2.3 | 2.4 |
tautz: manual_spc24 | 0.0 | 0.1 | 0.2 | -0.5 | 0.1 | 0.3 | 0.2 | 0.1 | -0.3 | -0.2 | 0.4 | 0.2 | 0.3 | 0.2 | -0.3 | 0.0 | 0.3 | 0.1 | -0.2 |
tautz: manual_spc4 | 2.1 | 3.0 | 4.3 | -1.8 | 1.9 | 1.7 | 1.7 | 1.9 | -1.9 | 1.6 | 2.1 | 1.0 | 1.9 | 1.9 | -1.9 | 0.0 | 1.9 | 1.7 | 1.7 |
tautz: manual_mpc9 | 0.3 | 0.4 | 0.9 | -0.1 | 0.6 | 0.1 | -0.9 | 0.7 | -0.7 | 0.7 | 0.5 | 0.8 | 0.7 | 0.7 | -0.7 | 0.0 | 0.7 | 0.8 | 0.5 |
tautz: manual_spc2 | 2.0 | 2.6 | 5.4 | 2.2 | -1.7 | -2.0 | -2.3 | -1.6 | 1.7 | -1.2 | -1.6 | -0.4 | -1.7 | -1.6 | 1.7 | 0.0 | -1.7 | -1.3 | -1.5 |
tautz: manual_spc13 | 1.0 | 1.5 | 2.1 | 1.3 | -1.4 | -1.4 | -0.4 | -1.4 | 1.4 | -1.1 | -1.2 | 1.1 | -1.4 | -1.4 | 1.4 | 0.0 | -1.4 | -1.1 | -1.2 |
tautz: manual_mpc19 | 0.2 | 0.2 | 0.9 | -0.4 | 0.3 | 0.5 | 0.9 | 0.4 | -0.3 | 0.6 | 0.3 | 0.9 | 0.3 | 0.3 | -0.3 | 0.0 | 0.3 | 0.5 | 0.6 |
tautz: manual_spc10 | 0.4 | 0.5 | 1.4 | 1.1 | -0.7 | -1.2 | -0.6 | -0.5 | 0.8 | 0.2 | -0.7 | 0.7 | -0.8 | -0.6 | 0.8 | 0.0 | -0.8 | -0.2 | -0.2 |
tautz: manual_spc11 | 3.0 | 3.8 | 5.7 | -1.5 | 2.4 | 1.8 | 0.2 | 2.3 | -2.4 | 1.8 | 2.3 | -0.2 | 2.4 | 2.4 | -2.4 | 0.0 | 2.4 | 1.9 | 2.1 |
tautz: manual_spc23 | 0.5 | 0.8 | 4.5 | -1.3 | 0.1 | 1.3 | 2.1 | -0.2 | -0.3 | -1.3 | 0.4 | -1.7 | 0.3 | 0.1 | -0.3 | 0.0 | 0.3 | -0.6 | -0.5 |
tautz: manual_spc6 | 4.2 | 6.0 | 9.6 | 3.1 | -2.7 | -2.7 | -1.7 | -2.7 | 2.8 | -2.0 | -2.5 | 0.7 | -2.8 | -2.7 | 2.8 | 0.0 | -2.8 | -2.4 | -2.2 |
tautz: manual_spc20 | 0.1 | 0.1 | 0.4 | 0.3 | 0.3 | 0.3 | 0.2 | 0.4 | -0.3 | 0.6 | 0.1 | 0.4 | 0.3 | 0.3 | -0.3 | 0.0 | 0.3 | 0.5 | 0.6 |
tautz: manual_mpc17 | 1.5 | 2.0 | 3.2 | -0.7 | 1.5 | 1.6 | 1.2 | 1.6 | -1.4 | 1.7 | 1.6 | 0.9 | 1.4 | 1.5 | -1.4 | 0.0 | 1.4 | 1.6 | 1.8 |
tautz: manual_mpc2 | 0.5 | 0.6 | 1.0 | -0.4 | 1.0 | 0.6 | -0.2 | 0.9 | -0.9 | 0.9 | 0.6 | -0.3 | 0.9 | 1.0 | -0.9 | 0.0 | 0.9 | 0.8 | 1.0 |
tautz: manual_spc1 | 1.5 | 1.8 | 2.6 | -1.0 | 1.4 | 1.3 | 1.4 | 1.4 | -1.3 | 1.5 | 1.4 | 1.3 | 1.3 | 1.3 | -1.3 | 0.0 | 1.3 | 1.6 | 1.5 |
tautz: manual_spc16 | 0.1 | 0.2 | 0.5 | 0.3 | -0.4 | -0.3 | -0.2 | -0.4 | 0.4 | -0.5 | -0.7 | 0.4 | -0.4 | -0.3 | 0.4 | 0.0 | -0.4 | -0.7 | -0.3 |
tautz: manual_mpc13 | 0.3 | 0.4 | 0.6 | -0.7 | 0.6 | 0.5 | 0.7 | 0.7 | -0.6 | 0.8 | 0.6 | 0.7 | 0.6 | 0.6 | -0.6 | 0.0 | 0.6 | 0.8 | 0.6 |
tautz: manual_spc5 | 1.4 | 1.9 | 8.5 | 0.6 | -1.2 | -0.6 | -0.9 | -1.4 | 0.9 | -2.2 | -1.1 | -2.9 | -0.9 | -1.1 | 0.9 | 0.0 | -0.9 | -2.0 | -1.7 |
tautz: manual_spc3 | 0.1 | 0.1 | 0.3 | -0.5 | 0.1 | 0.4 | 0.2 | 0.0 | -0.2 | -0.4 | 0.3 | -0.4 | 0.2 | 0.1 | -0.2 | 0.0 | 0.2 | -0.4 | -0.2 |
tautz: manual_mpc6 | 1.2 | 1.5 | 2.9 | -0.8 | 1.3 | 1.2 | 0.6 | 1.3 | -1.3 | 1.3 | 1.7 | 1.2 | 1.3 | 1.3 | -1.3 | 0.0 | 1.3 | 1.5 | 1.3 |
tautz: manual_spc18 | 0.4 | 0.5 | 0.8 | -0.1 | 0.8 | 0.5 | -0.5 | 0.8 | -0.8 | 0.5 | 0.9 | 0.0 | 0.8 | 0.8 | -0.8 | 0.0 | 0.8 | 0.8 | 0.7 |
tautz: manual_mpc11 | 1.7 | 2.2 | 3.2 | 1.1 | -1.8 | -1.4 | -0.7 | -1.7 | 1.8 | -1.4 | -1.8 | 0.6 | -1.7 | -1.7 | 1.7 | 0.0 | -1.7 | -1.5 | -1.7 |
tautz: manual_spc19 | 0.3 | 0.5 | 3.0 | 0.9 | -0.5 | -1.0 | -1.7 | -0.5 | 0.6 | -0.4 | -0.5 | -0.2 | -0.6 | -0.6 | 0.6 | 0.0 | -0.6 | -0.5 | -0.6 |
tautz: manual_mpc8 | 0.4 | 0.5 | 2.5 | 1.0 | -0.3 | -1.0 | -0.7 | -0.2 | 0.6 | 0.5 | -0.7 | 1.6 | -0.6 | -0.4 | 0.6 | 0.0 | -0.6 | 0.1 | 0.1 |
tautz: manual_mpc1 | 4.8 | 6.1 | 8.7 | -3.0 | 2.7 | 2.4 | 2.5 | 2.7 | -2.6 | 2.7 | 2.7 | 0.2 | 2.6 | 2.6 | -2.6 | 0.0 | 2.6 | 2.7 | 2.7 |
Sum of all infusions from LGA sessions | 0.1 | 0.1 | 0.4 | 0.3 | -0.2 | -0.1 | -0.2 | -0.2 | 0.0 | -0.1 | -0.4 | -0.6 | -0.1 | -0.0 | 0.3 | 0.0 | -0.3 | -0.3 | -0.2 |
Ambulatory time at time1 of open field | 0.0 | 0.0 | 0.2 | 0.4 | 0.1 | -0.0 | -0.2 | -0.0 | -0.2 | -0.1 | -0.4 | -0.4 | 0.1 | 0.0 | -0.0 | 0.0 | -0.0 | -0.2 | 0.2 |
dd_expon_k | 1.6 | 1.7 | 3.5 | 1.5 | -1.1 | -1.1 | -1.0 | -1.6 | 1.3 | -1.4 | -1.7 | -0.4 | -1.6 | -1.2 | 1.5 | 0.0 | -1.6 | -1.9 | -0.8 |
Delay discounting AUC-traditional | 1.6 | 1.7 | 3.3 | -1.5 | 1.1 | 1.1 | 0.9 | 1.5 | -1.3 | 1.3 | 1.7 | 0.1 | 1.6 | 1.2 | -1.5 | 0.0 | 1.6 | 1.8 | 0.7 |
The total number of resting periods in time1 | 0.6 | 0.7 | 1.6 | 1.1 | -1.0 | -1.0 | -1.1 | -0.7 | 0.8 | -0.4 | -1.3 | 0.1 | -0.5 | -1.1 | 0.7 | 0.0 | -0.8 | -0.8 | -0.6 |
Area under the delay curve | 1.6 | 1.7 | 3.3 | -1.5 | 1.1 | 1.1 | 0.9 | 1.5 | -1.3 | 1.3 | 1.7 | 0.1 | 1.6 | 1.2 | -1.5 | 0.0 | 1.6 | 1.8 | 0.7 |
punishment | 0.0 | 0.0 | 0.1 | -0.0 | -0.0 | -0.0 | 0.1 | -0.2 | 0.0 | -0.3 | -0.0 | -0.1 | -0.2 | -0.0 | 0.1 | 0.0 | -0.1 | -0.3 | -0.0 |
runstartmale1 | 1.1 | 1.1 | 2.7 | -0.9 | 1.1 | 0.9 | 0.7 | 1.1 | -1.2 | 1.0 | 1.6 | -0.1 | 1.2 | 1.1 | -1.2 | 0.0 | 1.2 | 1.4 | 0.8 |
locomotor2 | 0.5 | 0.6 | 1.3 | -1.0 | 0.6 | 1.1 | 1.1 | 0.7 | -0.8 | 0.5 | 0.9 | -0.2 | 0.9 | 0.6 | -0.8 | 0.0 | 0.8 | 0.7 | 0.5 |
Weight adjusted by age | 4.2 | 4.7 | 6.7 | -2.4 | 2.2 | 2.4 | 2.6 | 2.3 | -2.0 | 2.3 | 2.3 | 1.1 | 2.2 | 2.1 | -2.2 | 0.0 | 2.4 | 2.3 | 2.3 |
Liver selenium concentration | 0.8 | 0.9 | 7.3 | 1.0 | -0.5 | -1.4 | -1.0 | -0.2 | 0.8 | 0.8 | -0.6 | 2.7 | -0.8 | -0.6 | 0.6 | 0.0 | -0.7 | 0.2 | 0.0 |
Liver rubidium concentration | 0.8 | 1.0 | 1.9 | 1.4 | -1.1 | -1.0 | -1.0 | -1.0 | 1.2 | -0.8 | -0.9 | 0.0 | -1.2 | -1.2 | 1.2 | 0.0 | -1.2 | -1.0 | -1.0 |
Liver iron concentration | 0.4 | 0.5 | 2.3 | -0.9 | 0.6 | 0.9 | 0.9 | 0.4 | -0.6 | -0.2 | 0.8 | -1.5 | 0.7 | 0.6 | -0.7 | 0.0 | 0.6 | 0.2 | 0.3 |
Liver cobalt concentration | 1.2 | 1.4 | 3.5 | -1.7 | 1.0 | 1.6 | 1.9 | 1.0 | -1.1 | 0.5 | 1.5 | -0.7 | 1.2 | 1.1 | -1.2 | 0.0 | 1.2 | 0.9 | 0.6 |
Liver cadmium concentration | 0.3 | 0.3 | 1.4 | -0.3 | 0.5 | 0.7 | 0.1 | 0.4 | -0.6 | -0.3 | 0.3 | -1.2 | 0.6 | 0.6 | -0.7 | 0.0 | 0.7 | -0.1 | 0.3 |
Liver zinc concentration | 0.2 | 0.2 | 1.7 | 0.2 | 0.0 | -0.1 | 0.4 | 0.1 | 0.1 | 0.4 | 0.5 | 1.3 | -0.1 | -0.0 | -0.0 | 0.0 | -0.0 | 0.5 | 0.1 |
Liver sodium concentration | 0.1 | 0.1 | 1.5 | 0.1 | 0.1 | -0.2 | -1.2 | 0.2 | -0.2 | 0.1 | 0.5 | 0.4 | 0.0 | 0.1 | -0.3 | 0.0 | 0.1 | 0.2 | -0.1 |
Liver manganese concentration | 0.9 | 1.1 | 9.3 | 1.3 | -0.5 | -1.2 | -0.1 | -0.1 | 0.8 | 1.1 | -0.6 | 3.1 | -0.9 | -0.6 | 0.7 | 0.0 | -0.7 | 0.5 | 0.3 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.