Hub : Genes

Cchcr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000050233 0.42 0.12 0.0e+00 0.43 0.39 0.43 0.44 5.2e-52 9.5e-46 3.1e-52 4.0e-53
2 BLA gene expression ENSRNOG00000050233 0.9 0.04 0.0e+00 0.66 0.62 0.67 0.67 3.3e-46 4.9e-42 3.2e-47 7.9e-47
3 BLA intron excision ratio chr20:3217297:3217547 0.06 0.04 3.8e-03 0.01 0.01 0 0.01 1.2e-01 5.3e-02 1.6e-01 1.3e-01
4 BLA intron excision ratio chr20:3217362:3217547 0.09 0.06 2.4e-03 0.06 0.03 0.05 0.04 2.8e-04 7.3e-03 1.3e-03 3.6e-03
5 Brain gene expression ENSRNOG00000050233 0.75 0.06 0.0e+00 0.62 0.65 0.67 0.68 2.7e-72 6.7e-80 6.0e-84 6.3e-85
6 Brain mRNA stability ENSRNOG00000050233 0.28 0.1 0.0e+00 0.27 0.26 0.26 0.27 6.2e-25 3.1e-24 6.9e-24 4.0e-25
7 IL gene expression ENSRNOG00000050233 0.78 0.09 0.0e+00 0.46 0.49 0.49 0.48 2.1e-12 1.8e-13 1.8e-13 2.4e-13
8 LHb gene expression ENSRNOG00000050233 0.63 0.13 5.6e-12 0.42 0.37 0.39 0.41 4.3e-11 1.1e-09 3.7e-10 5.9e-11
9 Liver gene expression ENSRNOG00000050233 0.12 0.06 1.0e-08 0.08 0.07 0.09 0.08 2.0e-09 1.2e-08 8.2e-10 1.6e-09
10 NAcc gene expression ENSRNOG00000050233 0.62 0.09 0.0e+00 0.57 0.22 0.58 0.09 6.8e-51 1.3e-16 8.4e-52 6.2e-07
11 OFC alternative TSS ENSRNOT00000074049 0.17 0.11 7.7e-03 0.09 0.06 0.08 0.1 3.4e-03 1.5e-02 6.5e-03 2.9e-03
12 OFC alternative TSS ENSRNOT00000084918 0.17 0.11 8.3e-03 0.08 0.06 0.08 0.09 5.1e-03 1.7e-02 7.3e-03 3.9e-03
13 OFC gene expression ENSRNOG00000050233 0.88 0.05 0.0e+00 0.53 0.48 0.4 0.42 6.2e-15 5.9e-13 1.5e-10 4.6e-11
14 PL gene expression ENSRNOG00000050233 0.75 0.06 0.0e+00 0.7 0.19 0.74 0.04 1.5e-74 1.9e-14 1.6e-81 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.65.18.2-2.32.62.92.32.3-2.81.42.4-0.32.5-2.50.02.52.4
BMI without tail3.47.111.0-3.32.92.92.72.9-3.02.32.60.22.9-2.90.02.92.9
Body weight6.025.633.5-4.95.85.74.95.7-5.84.64.90.75.8-5.70.05.85.7
Epididymis fat weight1.12.712.3-2.40.82.41.60.7-1.4-1.11.1-3.51.0-1.50.01.40.5
Glucose1.21.818.11.4-0.3-1.2-0.50.10.51.3-0.64.2-0.20.60.0-0.60.2
Heart weight0.20.31.1-0.90.40.61.10.5-0.40.70.70.60.4-0.40.00.20.5
Left kidney weight3.610.314.3-3.23.83.63.13.5-3.62.83.40.13.7-3.60.03.63.6
Right kidney weight3.29.012.8-2.73.53.32.73.4-3.62.82.70.93.5-3.40.03.43.5
Tail length4.814.624.0-3.74.33.33.24.6-4.14.93.42.04.2-4.20.04.24.6
Length with tail4.416.222.6-3.54.63.93.54.8-4.44.64.01.64.6-4.60.04.64.7
Length without tail3.26.99.5-1.93.02.72.33.1-2.92.72.81.23.1-3.00.03.03.0
Liver weight, left0.50.91.4-0.61.11.01.01.1-0.91.10.30.81.1-0.90.01.01.2
Liver weight, right3.55.810.9-1.82.91.71.72.9-2.63.32.31.92.7-2.60.02.62.9
Parametrial fat weight1.73.35.2-1.72.12.11.41.9-2.30.92.0-1.12.2-2.20.02.21.9
Retroperitoneal fat weight0.31.12.0-1.21.01.41.21.1-1.10.70.6-0.31.1-1.20.01.21.1
Intraocular pressure1.31.83.61.5-1.3-0.9-1.3-1.51.2-1.9-1.8-1.1-1.21.30.0-1.3-1.3
Extensor digitorum longus weight0.10.53.70.00.50.30.40.6-0.41.00.21.90.5-0.40.00.40.7
Soleus weight1.02.815.3-0.11.30.31.11.7-1.03.10.93.91.3-0.90.00.91.8
Tibialis anterior weight0.00.10.7-0.3-0.20.20.0-0.3-0.1-0.7-0.4-0.8-0.10.10.0-0.0-0.3
Tibia length2.88.013.0-2.23.12.82.63.3-2.93.62.72.83.1-2.90.02.93.3
Number of licking bursts0.20.21.10.6-0.3-0.8-0.4-0.10.40.5-0.01.1-0.30.50.0-0.4-0.1
Food consumed during 24 hour testing period0.80.91.8-0.31.20.90.61.2-1.11.30.60.51.2-1.10.01.11.3
Times rat made contact with spout2.02.25.30.6-1.5-1.1-1.4-1.61.4-2.1-1.6-2.3-1.61.30.0-1.3-1.7
Mean time between licks in bursts0.40.54.80.70.2-0.6-0.40.30.01.2-0.12.20.20.10.00.00.4
Mean num. licks in bursts0.60.75.3-0.3-0.40.2-0.2-0.60.3-1.5-0.8-2.3-0.50.20.0-0.3-0.7
Std. dev. time between licks in bursts0.70.96.20.10.5-0.20.40.8-0.31.80.72.50.5-0.30.00.40.8
Water consumed over 24 hours0.00.10.20.10.1-0.10.10.2-0.10.50.40.50.1-0.00.00.00.2
Indifference point 0 sec0.40.73.6-1.50.41.21.00.2-0.3-0.30.0-1.90.4-0.60.00.50.3
Indifference point AUC2.12.53.7-1.61.81.20.91.9-1.91.71.7-0.11.8-1.80.01.91.7
Indifference point function ln k0.30.51.30.7-0.6-0.8-0.5-0.60.70.0-0.91.2-0.60.80.0-0.8-0.5
Indifference point function log k0.30.51.30.7-0.6-0.8-0.5-0.60.70.0-0.91.2-0.60.80.0-0.8-0.5
Delay discounting total patch changes 0 sec0.50.83.9-1.60.51.41.10.3-0.5-0.30.2-2.00.5-0.80.00.60.4
Delay discounting total patch changes 12 sec0.60.82.3-1.50.71.10.90.6-0.8-0.01.0-1.50.7-0.80.00.80.5
Delay discounting total patch changes 18 sec0.60.89.1-0.5-0.10.60.0-0.5-0.0-1.30.1-3.0-0.1-0.10.00.1-0.5
Delay discounting total patch changes 24 sec1.11.47.10.1-1.0-0.4-0.9-1.31.0-1.9-0.4-2.7-1.10.80.0-0.7-1.4
Delay discounting total patch changes 6 sec0.50.85.0-1.50.51.10.90.3-0.4-0.40.1-2.20.5-0.60.00.70.2
Delay discounting time to switch 0 sec0.40.62.10.6-0.8-0.10.2-1.00.8-1.4-0.4-1.0-0.70.70.0-0.7-0.9
Delay discounting water rate 0 sec0.40.61.0-0.70.80.80.50.9-0.91.00.7-0.20.9-0.80.00.70.9
Delay discounting water rate 12 sec0.20.30.90.3-0.4-0.3-0.9-0.50.5-0.6-0.4-1.0-0.40.30.0-0.3-0.5
Delay discounting water rate 18 sec0.20.20.5-0.50.40.60.10.6-0.60.5-0.40.00.5-0.70.00.60.6
Delay discounting water rate 24 sec1.21.63.1-1.11.51.20.61.5-1.80.91.10.71.6-1.60.01.51.5
Delay discounting water rate 6 sec0.10.11.40.0-0.10.0-0.2-0.0-0.1-0.2-0.1-1.2-0.1-0.10.00.0-0.1
Locomotor activity1.32.03.4-1.41.81.21.61.6-1.41.81.20.91.5-1.40.01.41.7
Locomotor testing distance0.20.41.0-0.70.80.61.00.6-0.50.80.40.60.6-0.40.00.40.7
Locomotor testing rearing0.50.91.5-0.81.21.01.20.9-0.91.10.90.31.1-0.80.00.91.1
Light reinforcement 10.10.10.8-0.10.10.50.30.1-0.0-0.10.2-0.90.2-0.30.00.20.2
Light reinforcement 20.60.71.3-0.41.00.90.61.1-1.00.90.2-0.61.0-1.10.01.01.1
Reaction time number correct0.20.21.0-0.6-0.00.80.9-0.2-0.3-0.50.2-1.00.0-0.20.0-0.0-0.1
Reaction time mean minus median0.30.31.41.20.2-0.9-1.00.20.10.6-0.31.00.0-0.10.00.10.3
Reaction time mean minus median AUC0.30.41.81.4-0.1-1.0-1.1-0.10.40.2-0.41.0-0.20.20.0-0.2-0.0
Reaction time num false alarms0.40.51.3-0.50.80.30.10.9-0.81.20.50.70.8-0.80.00.60.9
Reaction time num false alarms AUC0.70.92.2-0.91.00.50.51.2-1.11.50.90.91.0-1.00.00.91.1
Reaction time trials correct on left0.20.21.0-0.6-0.00.80.9-0.2-0.3-0.50.2-1.00.0-0.20.0-0.0-0.1
Reaction time trials on left0.20.20.9-0.60.00.80.9-0.1-0.3-0.40.2-0.90.1-0.20.0-0.0-0.0
Reaction time mean0.50.62.81.7-0.3-1.1-1.1-0.20.60.4-0.81.4-0.30.40.0-0.5-0.1
Reaction time mean AUC0.40.62.61.6-0.3-1.1-1.0-0.20.60.4-0.81.3-0.30.40.0-0.5-0.1
Median of all reaction times0.40.52.21.5-0.4-0.9-0.8-0.20.60.4-0.91.3-0.30.50.0-0.6-0.1
Reaction time omissions0.30.42.41.2-0.0-0.8-0.8-0.10.30.2-0.61.5-0.20.30.0-0.30.1
Reaction time false alarm rate0.50.82.6-0.50.8-0.0-0.11.1-0.71.60.71.50.8-0.70.00.71.0
Reaction time premature initiation rate1.31.82.5-1.31.51.41.31.5-1.41.31.30.61.5-1.60.01.51.4
Reaction time premature initiations1.52.23.6-1.71.61.91.91.5-1.61.11.40.21.6-1.70.01.61.4
Std. dev. reaction times0.30.41.80.90.3-0.8-0.70.40.11.0-0.11.30.2-0.10.00.10.5
Reaction time trials completed0.20.20.9-0.60.00.80.9-0.1-0.3-0.40.2-0.90.1-0.20.0-0.0-0.0
Reaction time trials AUC0.10.20.9-0.5-0.00.70.9-0.2-0.2-0.50.2-1.0-0.0-0.20.0-0.1-0.1
Social response proportion0.40.52.4-0.50.30.51.00.6-0.11.00.81.50.4-0.40.00.30.5
Social responses0.50.61.8-0.90.40.61.20.7-0.31.01.11.40.5-0.50.00.40.7
Social time0.60.85.70.50.6-0.4-0.30.8-0.21.50.82.40.6-0.50.00.40.8
Conditioned locomotion0.70.91.4-0.61.10.90.81.2-1.01.20.60.71.1-1.10.01.01.1
Cocaine response after cond. corrected0.50.61.41.2-0.9-0.8-0.7-0.80.8-0.6-0.60.7-0.70.80.0-0.8-0.7
Cocaine response after cond. not corrected0.30.42.0-0.00.50.20.30.6-0.40.90.61.40.5-0.40.00.40.6
Cocaine response before conditioning5.36.49.3-2.72.82.42.32.9-2.73.02.80.92.7-2.60.02.72.9
Saline control response1.01.44.4-1.81.11.71.10.7-1.1-0.00.7-2.11.0-1.00.01.20.8
Condit. Reinf. active minus inactive responses1.41.72.5-1.61.41.31.51.4-1.41.51.40.31.4-1.40.01.41.4
Condit. Reinf. active-inactive response ratio3.13.34.9-1.92.01.61.82.0-1.92.22.10.91.9-1.90.01.92.0
Condit. Reinf. active responses0.00.00.3-0.40.00.20.5-0.00.00.1-0.1-0.0-0.00.00.0-0.00.0
Condit. Reinf. inactive responses1.51.93.41.1-1.5-1.0-0.5-1.71.6-1.7-1.8-0.8-1.61.60.0-1.6-1.6
Condit. Reinf. lever presses0.30.50.80.3-0.7-0.6-0.1-0.90.8-0.8-0.90.3-0.80.80.0-0.8-0.8
Condit. Reinf. lever reinforcers received0.00.00.2-0.2-0.1-0.00.5-0.20.20.0-0.20.1-0.20.20.0-0.2-0.1
Pavlov. Cond. lever latency0.30.40.7-0.30.60.40.40.8-0.60.80.70.40.7-0.70.00.70.7
Pavlov. Cond. magazine entry latency0.50.61.0-0.41.00.5-0.10.9-1.00.90.80.80.9-0.90.00.90.9
Pavlov. Cond. change in total contacts0.10.20.5-0.70.40.4-0.10.2-0.50.00.3-0.60.3-0.40.00.40.3
Pavlov. Cond. index score0.00.00.1-0.10.1-0.0-0.3-0.0-0.2-0.1-0.10.20.0-0.00.00.00.0
Pavlov. Cond. latency score0.00.10.1-0.40.30.2-0.00.1-0.40.00.10.20.2-0.20.00.20.2
Pavlov. Cond. lever contacts0.30.41.50.0-0.4-0.2-0.5-0.70.3-1.0-0.6-1.2-0.50.40.0-0.5-0.6
Pavlov. Cond. magazine entry number0.20.30.60.2-0.7-0.40.5-0.60.8-0.4-0.3-0.0-0.70.70.0-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.81.11.91.2-1.1-1.4-0.4-0.91.3-0.2-1.11.3-1.11.30.0-1.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.10.20.0-0.2-0.0-0.2-0.1-0.10.20.1-0.00.00.00.1
Pavlov. Cond. response bias0.20.20.80.3-0.3-0.4-0.9-0.50.2-0.7-0.6-0.7-0.40.30.0-0.3-0.5
Conditioned reinforcement - actives0.40.40.8-0.80.70.60.70.7-0.60.60.70.90.7-0.70.00.70.6
Conditioned reinforcement - inactives0.80.92.2-1.51.11.00.80.9-1.00.50.9-0.11.0-1.10.01.10.9
Conditioned locomotion0.10.10.4-0.10.10.20.50.3-0.00.30.20.60.1-0.30.00.30.2
Intermittent access intake day 1-15 change0.50.52.2-0.70.70.60.10.7-0.70.2-0.0-1.50.8-0.90.01.00.6
Intermittent access intake escalation0.20.20.8-0.10.50.2-0.20.5-0.40.3-0.3-0.90.6-0.60.00.60.5
Intermittent access intake escalation 20.20.20.50.60.2-0.5-0.70.4-0.10.7-0.60.50.3-0.20.00.20.4
Intermitt. access day 1 inactive lever presses0.50.51.9-0.20.60.40.80.6-0.41.10.91.40.6-0.40.00.40.7
Intermitt. access day 15 inactive lever presses2.42.74.0-1.92.01.71.61.7-1.81.41.80.31.8-1.80.01.81.8
Intermitt. access escalation Index2.92.63.61.9-1.8-1.8-1.4-1.81.7-1.4-1.30.1-1.91.90.0-1.9-1.8
Intermittent access day 1 total infusions0.60.61.00.6-0.8-0.9-1.0-0.90.9-0.9-0.80.1-0.90.80.0-0.8-0.9
Intermittent access day 15 total infusions0.20.20.50.2-0.3-0.4-0.7-0.40.5-0.6-0.7-0.7-0.30.20.0-0.2-0.4
Intermittent access terminal intake (last 3 days)0.00.00.2-0.40.10.10.00.2-0.00.00.1-0.20.2-0.20.00.30.1
Intermittent access total infusions0.00.00.2-0.1-0.1-0.1-0.2-0.20.2-0.4-0.3-0.2-0.20.10.0-0.1-0.3
Intermittent access day 1 locomotion0.20.20.50.3-0.5-0.3-0.3-0.40.6-0.4-0.70.5-0.50.40.0-0.4-0.4
Intermittent access day 15 total locomotion0.70.71.4-0.71.00.90.61.1-0.90.90.1-0.21.0-1.20.01.21.0
Intermittent access total locomotion0.30.30.6-0.40.70.70.30.7-0.60.5-0.2-0.10.8-0.80.00.80.7
Intermittent access standard deviation2.12.33.5-1.81.41.91.71.6-1.61.01.5-0.51.6-1.70.01.71.5
Cocaine induced anxiety2.12.45.12.2-1.3-1.6-1.7-1.51.7-1.1-2.10.5-1.51.70.0-1.7-1.4
Post-drug Anxiety0.50.61.31.1-0.5-0.7-0.3-0.80.9-0.4-0.81.0-0.81.00.0-1.0-0.6
Baseline Anxiety0.30.31.2-1.00.10.51.10.2-0.20.31.10.60.1-0.10.00.10.2
Lifetime Intake0.00.00.1-0.2-0.0-0.0-0.1-0.10.2-0.2-0.10.3-0.10.00.0-0.0-0.1
Incentive Sensitization - Responses0.90.91.60.9-0.9-1.0-1.3-1.00.9-1.1-1.2-0.5-1.00.90.0-0.9-1.0
Incentive Sensitization - Breakpoint1.11.11.91.1-1.0-1.1-1.4-1.11.0-1.2-1.4-0.5-1.01.00.0-1.0-1.1
Progressive ratio test 1 active lever presses0.20.20.30.0-0.5-0.4-0.3-0.40.6-0.3-0.30.3-0.50.50.0-0.5-0.5
Progressive ratio test 1 breakpoint0.10.10.3-0.0-0.5-0.3-0.2-0.40.6-0.2-0.20.5-0.40.50.0-0.4-0.5
Progressive ratio test 1 inactive lever presses0.10.10.2-0.2-0.20.0-0.1-0.30.2-0.5-0.2-0.3-0.20.20.0-0.2-0.3
Progressive ratio test 2 active lever presses0.80.81.30.7-0.9-0.9-1.1-1.01.0-1.1-1.1-0.4-1.00.90.0-0.9-1.1
Progressive ratio test 2 breakpoint1.31.52.41.0-1.3-1.2-1.5-1.31.3-1.5-1.6-0.6-1.31.20.0-1.2-1.4
Progressive ratio test 2 inactive lever presses0.20.30.5-0.60.70.30.10.6-0.50.60.40.00.6-0.60.00.60.6
Total sessions with >9 infusions0.10.10.9-0.30.20.10.10.2-0.00.20.10.90.2-0.30.00.30.1
Short access day 1 total inactive lever presses0.40.54.00.10.6-0.00.10.6-0.21.10.32.00.5-0.30.00.30.7
Short access day 10 total inactive lever presses0.00.00.20.40.2-0.2-0.10.2-0.10.50.00.30.1-0.00.00.00.2
Short access day 1 total infusions0.30.42.00.2-0.6-0.6-0.2-0.50.7-0.2-0.21.4-0.60.60.0-0.6-0.5
Short access day 10 total infusions0.10.10.4-0.60.20.20.20.4-0.10.40.30.60.3-0.40.00.40.3
Short access total infusions0.20.21.4-0.70.20.20.30.3-0.10.40.51.20.2-0.30.00.30.2
Short access day 1 locomotion2.83.04.71.8-2.0-1.9-1.6-1.82.2-1.3-1.81.0-2.01.90.0-1.9-1.9
Short access day 10 total locomotion0.60.74.6-0.40.10.41.10.6-0.11.30.82.20.3-0.20.00.20.7
Short access total locomotion0.20.22.3-0.0-0.4-0.10.5-0.10.50.30.11.5-0.30.30.0-0.2-0.1
Compulsive drug intake2.72.64.22.0-1.8-2.0-1.4-1.71.9-0.9-1.10.9-1.92.00.0-2.0-1.7
One hour access (0.3 mA shock)0.91.02.61.3-0.9-1.3-1.6-0.91.1-0.8-1.10.0-0.90.90.0-0.9-1.0
One hour access (shock baseline)0.40.40.9-0.60.90.70.20.7-0.70.30.0-0.50.8-0.90.00.90.7
Number of responses in last shaping day0.70.73.2-1.00.70.30.90.8-0.41.21.11.80.5-0.50.00.50.7
Context. condit. distance diff. score4.15.010.03.2-2.3-2.8-2.0-2.12.6-1.0-2.31.9-2.32.40.0-2.4-2.0
Locomotion velocity, session 10.10.10.40.2-0.3-0.60.1-0.20.40.1-0.5-0.0-0.30.40.0-0.3-0.2
Locomotion distance, session 10.50.71.20.6-0.9-0.9-0.6-0.90.8-1.1-0.9-1.0-0.80.80.0-0.7-1.0
Locomotion velocity, session 20.10.10.60.20.1-0.4-0.30.1-0.00.30.00.80.1-0.00.00.00.1
Locomotion distance, session 20.40.61.21.1-0.8-1.0-0.9-0.80.7-0.7-1.0-0.1-0.70.70.0-0.7-0.8
Locomotion velocity, session 30.20.21.7-0.60.00.30.5-0.1-0.1-0.40.0-1.3-0.0-0.10.00.1-0.1
Locomotion distance, session 31.81.92.41.5-1.4-1.5-1.4-1.51.5-1.5-1.6-0.5-1.51.50.0-1.5-1.5
Stereotopy head waving bouts, day 31.92.24.4-1.31.71.21.11.8-1.62.11.50.61.7-1.60.01.61.8
Stereotopy head waving duration, day 31.51.83.2-1.61.41.31.51.6-1.41.81.20.31.4-1.40.01.41.5
Locomotion velocity, session 74.65.18.32.9-2.3-2.5-2.6-2.42.4-2.2-2.5-0.1-2.32.40.0-2.4-2.3
Locomotion distance, session 74.75.99.32.9-2.6-2.8-3.1-2.62.5-2.5-2.50.3-2.52.50.0-2.5-2.6
Stereotopy head waving bouts, day 71.82.13.0-1.71.61.20.91.7-1.71.41.7-0.71.6-1.60.01.61.5
Stereotopy head waving duration, day 72.53.14.2-2.02.01.61.32.0-2.01.81.9-0.61.9-2.00.02.01.9
Locomotion velocity, session 80.50.63.90.60.4-0.6-0.10.7-0.11.70.32.00.4-0.30.00.30.6
Locomotion distance, session 82.63.99.63.1-2.0-2.6-2.2-1.82.1-1.0-2.11.6-1.82.00.0-2.0-1.7
Degree of sensitization distance0.40.42.90.7-0.5-0.6-0.4-0.20.50.2-0.31.7-0.40.40.0-0.4-0.2
Degree of sensitization stereotypy1.01.11.8-1.21.30.70.21.2-1.31.01.3-0.51.1-1.30.01.21.1
Condit. Reinf. active minus inactive responses0.80.91.90.7-1.0-1.0-0.7-1.01.0-0.9-1.40.1-1.11.00.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.00.00.3-0.5-0.10.10.3-0.20.0-0.3-0.2-0.2-0.10.00.00.0-0.1
Condit. Reinf. active responses1.41.73.31.2-1.4-1.3-1.0-1.51.4-1.4-1.80.1-1.41.40.0-1.3-1.4
Condit. Reinf. inactive responses2.53.04.91.8-1.8-1.6-1.8-2.01.7-2.2-2.1-0.5-1.81.80.0-1.7-1.9
Incentive salience index mean1.41.73.11.6-1.2-1.7-1.5-1.11.3-0.6-1.81.3-1.21.30.0-1.3-1.1
Condit. Reinf. lever presses2.43.26.72.6-1.6-2.2-2.1-1.51.7-0.7-2.22.2-1.51.80.0-1.7-1.4
Time in familiar zone, hab. session 13.93.78.01.3-2.1-1.5-1.6-2.42.0-2.8-1.9-1.2-2.22.00.0-2.0-2.3
Time in novel zone, hab. session 12.22.15.0-1.11.61.31.81.7-1.42.21.40.41.6-1.40.01.41.7
Total zone transitions, hab. session 10.60.81.30.8-1.1-1.0-0.4-1.01.0-0.8-1.00.2-1.01.00.0-1.0-1.0
Total locomotion distance, hab. session 10.60.81.11.1-1.1-1.0-1.0-1.01.0-0.8-1.00.3-1.01.00.0-1.0-1.0
Locomotion velocity, hab. session 10.30.40.60.6-0.8-0.7-0.7-0.70.6-0.6-0.60.5-0.70.60.0-0.7-0.7
Time in familiar zone, hab. session 20.40.41.20.3-0.7-0.3-0.5-0.80.6-1.1-0.5-0.0-0.70.60.0-0.7-0.7
Time in novel zone, hab. session 20.50.61.8-0.70.70.61.10.7-0.60.70.4-1.30.7-0.60.00.70.6
Total zone transitions, hab. session 20.00.00.10.2-0.2-0.2-0.1-0.20.1-0.3-0.1-0.0-0.10.10.0-0.1-0.2
Total locomotion distance, hab. session 21.21.62.51.6-1.4-1.3-1.2-1.41.4-1.3-1.4-0.0-1.31.40.0-1.4-1.4
Locomotion velocity, hab. session 21.31.83.01.7-1.5-1.5-1.4-1.41.4-1.2-1.40.3-1.41.40.0-1.5-1.4
Novel to familiar place preference ratio0.10.10.7-0.1-0.1-0.2-0.30.00.0-0.00.1-0.9-0.0-0.00.00.1-0.1
Novelty place preference0.10.10.7-0.40.20.00.00.3-0.20.30.3-0.80.2-0.30.00.30.2
Time in novel zone, NPP test0.20.20.7-0.60.40.20.20.5-0.40.50.4-0.80.4-0.40.00.50.3
Total zone transitions, NPP test1.21.72.61.6-1.5-1.4-1.0-1.41.4-1.2-1.6-0.3-1.31.40.0-1.4-1.4
Total locomotion distance, NPP test1.31.93.01.7-1.5-1.3-1.3-1.51.4-1.4-1.6-0.7-1.41.40.0-1.5-1.5
Locomotion velocity, NPP test2.23.14.92.2-2.0-1.8-1.7-2.01.9-1.8-1.9-0.7-1.81.90.0-1.9-1.9
Pavlov. Cond. lever latency1.21.57.7-1.60.51.71.90.4-0.7-0.51.0-2.80.6-0.70.00.70.4
Pavlov. Cond. magazine entry latency0.91.14.51.2-0.7-1.5-1.3-0.50.90.2-1.32.1-0.80.80.0-0.8-0.6
Pavlov. Cond. change in total contacts1.01.07.2-0.20.9-0.0-0.41.0-0.81.30.32.70.8-0.80.00.91.0
Pavlov. Cond. index score1.41.810.21.6-0.7-1.8-1.9-0.50.90.4-1.33.2-0.80.90.0-0.8-0.5
Pavlov. Cond. latency score1.21.510.01.4-0.3-1.6-1.9-0.10.60.7-0.93.2-0.40.50.0-0.5-0.2
Pavlov. Cond. lever contacts1.11.210.21.3-0.0-1.2-1.70.10.20.9-0.63.2-0.10.20.0-0.20.1
Pavlov. Cond. magazine entry number1.31.65.0-1.31.21.60.91.0-1.30.41.7-2.21.3-1.30.01.21.0
Pavlov. Cond. intertrial magazine entries1.01.27.20.3-1.0-0.10.1-1.10.8-1.6-0.9-2.7-0.90.80.0-0.8-1.1
Pavlov. Cond. lever-magazine prob. diff.1.51.910.11.7-0.8-1.8-1.9-0.61.00.2-1.43.2-0.91.00.0-0.9-0.6
Pavlov. Cond. response bias1.51.88.21.6-0.9-1.7-1.5-0.81.10.0-1.62.9-1.01.10.0-1.1-0.7
Bone: apparent density1.93.15.21.8-1.8-1.6-2.0-2.01.7-2.3-1.9-1.7-1.81.70.0-1.7-1.9
Bone surface0.10.20.4-0.00.50.3-0.30.6-0.50.60.20.40.5-0.50.00.50.5
Bone volume0.00.10.30.00.20.2-0.50.1-0.3-0.2-0.0-0.50.2-0.30.00.30.1
Bone: connectivity density2.74.36.12.5-2.2-2.0-1.9-2.32.2-2.2-2.4-0.9-2.22.20.0-2.2-2.2
Bone: cortical apparent density0.30.42.2-0.90.41.00.60.2-0.5-0.50.3-1.50.4-0.50.00.60.2
Bone: cortical area1.82.84.2-1.61.91.60.62.0-2.01.71.60.52.0-2.00.02.01.9
Bone: cortical porosity0.50.51.8-1.40.60.50.40.7-0.70.51.0-0.40.6-0.80.00.70.5
Bone: cortical porosity0.80.81.7-1.31.00.50.61.1-1.01.21.10.30.9-1.00.00.90.9
Bone: cortical thickness1.83.04.7-2.11.82.00.61.7-2.20.61.9-1.51.9-2.20.02.21.6
Bone: cortical thickness0.40.41.7-1.00.30.90.60.3-0.6-0.60.4-1.30.4-0.70.00.70.2
Bone: cortical tissue density0.30.41.8-0.90.30.90.70.2-0.4-0.50.3-1.40.4-0.50.00.50.2
Bone: elastic displacement0.20.33.0-0.60.20.20.30.0-0.2-0.30.3-1.70.1-0.20.00.2-0.1
Bone: elastic work1.41.92.7-1.51.61.30.71.5-1.61.11.5-1.01.5-1.60.01.61.4
Bone: endosteal estimation3.26.814.3-2.02.72.22.83.0-2.43.82.13.22.6-2.40.02.43.0
Bone: endosteal perimeter0.81.712.50.10.80.21.01.1-0.52.20.43.50.8-0.50.00.51.2
Bone: final force4.67.611.8-2.83.13.21.63.1-3.32.22.8-0.23.2-3.40.03.43.0
Bone: final moment4.27.010.9-2.73.03.01.53.0-3.22.12.6-0.33.1-3.30.03.32.9
Bone: marrow area3.26.814.1-2.02.72.22.93.0-2.43.82.13.22.6-2.40.02.43.0
Bone: maximum diameter0.91.65.7-0.31.20.40.21.5-1.12.10.82.41.3-1.10.01.11.5
Bone: maximum force4.06.910.5-2.73.02.91.53.0-3.22.22.5-0.43.1-3.20.03.22.9
Bone: maximum moment3.76.59.8-2.62.92.81.52.9-3.12.22.3-0.33.0-3.10.03.12.8
Bone: minimum diameter1.22.29.8-0.51.40.80.91.6-1.22.30.93.11.4-1.20.01.21.7
Bone: periosteal estimation3.26.610.7-2.22.82.42.33.0-2.73.32.22.32.8-2.70.02.73.0
Bone: periosteal perimeter1.52.55.2-1.01.71.10.91.9-1.62.31.42.21.7-1.60.01.61.9
Bone: post-yield work0.10.21.00.30.20.10.30.3-0.10.8-0.61.00.3-0.10.00.10.4
Bone: stiffness0.81.22.2-1.21.21.50.51.2-1.40.60.8-0.21.3-1.40.01.51.2
Bone: tissue strength3.43.34.9-1.62.21.80.82.0-2.21.52.0-1.02.2-2.20.02.22.0
Bone: trabecular number2.33.65.91.9-1.8-1.7-2.3-2.01.7-2.4-2.0-2.3-1.81.70.0-1.6-2.0
Bone: trabecular spacing4.55.87.9-2.42.62.42.22.7-2.62.82.71.92.6-2.50.02.42.7
Bone: trabecular thickness1.51.93.51.4-1.4-1.2-1.5-1.51.3-1.9-1.5-1.2-1.31.30.0-1.3-1.5
Bone: trabecular tissue density1.62.23.5-1.91.71.30.91.7-1.81.51.80.61.6-1.70.01.71.6
Breakpoint value in progressive ratio session1.01.11.61.0-1.2-1.2-1.0-1.11.2-0.7-0.80.7-1.21.30.0-1.2-1.1
Distance traveled before self-admin0.10.10.40.60.1-0.0-0.20.1-0.10.2-0.30.70.10.00.0-0.00.2
Distance traveled after self-admin0.40.41.1-0.70.60.81.00.7-0.40.80.50.20.6-0.60.00.60.7
Delta time in closed arm before/after self-admin0.30.31.0-0.40.30.71.00.5-0.60.80.80.20.4-0.40.00.40.5
Delta time in open arm before/after self-admin0.00.00.3-0.10.10.1-0.1-0.10.0-0.4-0.4-0.50.1-0.00.00.0-0.0
Diff in mean of infusions in LGA sessions3.94.36.52.4-2.2-2.3-2.6-2.22.4-1.9-1.90.2-2.12.30.0-2.3-2.2
Extinction: sum of active levers before priming0.50.50.80.5-0.9-0.8-0.6-0.70.8-0.4-0.30.4-0.70.90.0-0.9-0.8
Active lever presses in extinction session 60.10.10.8-0.0-0.30.10.1-0.40.4-0.50.1-0.9-0.30.20.0-0.3-0.3
Delta distance traveled before/after self-admin1.21.33.2-1.81.11.21.31.1-0.80.91.2-0.61.1-1.20.01.21.1
Delta ambulatory time before/after self-admin0.50.61.3-1.10.90.71.00.7-0.50.80.9-0.10.7-0.70.00.70.8
Time in closed arm before self-admin0.00.00.1-0.10.10.00.3-0.00.0-0.00.10.3-0.10.10.0-0.1-0.0
Time in closed arm after self-admin0.60.61.3-0.90.70.80.80.8-0.90.61.1-0.50.8-0.90.00.80.7
Time in open arm before self-admin0.20.20.70.4-0.5-0.7-0.8-0.40.6-0.1-0.8-0.3-0.40.40.0-0.4-0.4
Time in open arm after self-admin0.60.71.50.6-0.9-0.8-0.7-0.91.1-0.6-1.2-0.2-0.90.90.0-0.9-0.8
Sum of active levers in priming session hrs 5-60.30.30.90.3-0.6-0.6-0.2-0.50.9-0.3-0.20.2-0.70.70.0-0.7-0.7
Time to tail flick, vehicle, before self-admin0.20.21.11.00.1-0.7-1.0-0.20.2-0.3-0.80.1-0.20.30.0-0.1-0.3
Time to tail flick, vehicle, after self-admin0.50.51.41.2-0.6-0.9-0.7-0.60.7-0.3-0.90.6-0.60.70.0-0.8-0.5
Time to tail flick, test, before self-admin0.10.11.00.00.1-0.1-0.5-0.1-0.2-0.2-0.0-1.00.10.00.00.1-0.1
Time to tail flick, test, after self-admin1.41.44.31.5-1.0-1.4-1.7-0.91.0-1.0-2.1-1.1-1.01.00.0-0.9-1.0
Delta time to tail flick, vehicle, before/after SA0.60.51.00.7-0.9-0.7-0.5-0.90.8-0.7-0.7-0.4-0.80.80.0-1.0-0.8
Delta time to tail flick, test, before/after SA1.21.12.81.2-1.1-0.9-0.9-1.01.1-1.1-1.7-0.7-1.00.90.0-1.0-1.0
Ambulatory time before self-admin0.00.00.20.40.1-0.0-0.2-0.0-0.2-0.1-0.4-0.40.2-0.00.0-0.00.1
Ambulatory time after self-admin0.20.20.5-0.50.60.50.70.4-0.30.50.4-0.10.5-0.40.00.40.6
Total heroin consumption0.10.10.40.3-0.2-0.1-0.2-0.20.0-0.1-0.4-0.6-0.10.30.0-0.3-0.2
Area under the delay curve1.51.62.9-1.51.11.10.91.5-1.31.31.70.11.4-1.50.01.61.3
Delay disc. indifference point, 0s delay0.50.51.3-0.30.60.30.30.9-0.81.10.71.10.7-0.70.00.70.8
Delay disc. indifference point, 16s delay0.70.71.7-1.30.40.80.50.9-0.70.41.1-0.90.8-1.10.01.10.6
Delay disc. indifference point, 2s delay2.32.64.7-1.71.71.21.51.8-1.72.02.21.31.7-1.50.01.61.7
Delay disc. indifference point, 24s delay0.50.51.3-1.20.40.71.00.7-0.50.61.00.30.5-0.70.00.70.5
Delay disc. indifference point, 4s delay2.62.73.9-1.81.51.51.52.0-1.71.91.70.81.8-1.80.01.91.8
Delay disc. indifference point, 8s delay0.20.20.5-0.60.20.20.10.7-0.30.50.7-0.20.5-0.70.00.70.4
Delay discount exponential model param1.51.62.91.6-1.0-1.1-1.0-1.51.2-1.3-1.7-0.2-1.31.50.0-1.6-1.2
Delay discount hyperbolic model param1.71.83.21.7-1.2-1.1-1.1-1.61.3-1.4-1.8-0.3-1.41.50.0-1.6-1.3
Fecal boli incidents, locomotor time 10.60.71.20.8-0.8-0.6-0.4-1.10.9-1.0-0.80.2-0.91.10.0-1.1-1.0
Change in fecal boli incidents, locomotor task1.11.12.8-0.70.90.50.81.1-0.81.61.71.60.8-0.80.00.91.0
Time >=10cm from walls, locomotor time 10.90.92.0-0.31.21.01.41.0-1.01.31.01.01.0-0.50.00.61.1
Bouts of movement, locomotor time 11.21.32.71.4-1.3-1.3-1.4-1.11.1-0.8-1.6-0.1-1.21.10.0-1.2-1.0
Total resting periods, locomotor time 10.60.71.61.1-1.0-1.0-1.1-0.70.8-0.4-1.30.1-0.80.70.0-0.8-0.6
Rest time, locomotor task time 10.00.00.1-0.00.30.00.20.1-0.10.4-0.40.00.1-0.00.0-0.10.3
Distance moved, locomotor task time 10.40.50.9-0.80.70.80.60.7-0.90.41.0-0.10.7-0.70.00.90.6
Vertical activity count, locomotor time 10.30.30.8-0.50.50.70.60.3-0.9-0.10.7-0.60.5-0.40.00.50.4
Time >=10cm from walls, locomotor time 20.40.52.2-0.20.50.61.50.4-0.60.70.81.30.40.00.00.10.4
Bouts of movement, locomotor time 20.50.50.9-0.60.90.50.51.0-0.90.90.4-0.10.9-0.80.00.80.9
Total resting periods, locomotor time 20.30.30.9-0.40.70.20.40.8-0.61.00.20.20.7-0.70.00.60.7
Rest time, locomotor task time 20.20.31.31.10.1-0.5-0.30.00.20.6-0.71.10.10.20.0-0.40.3
Distance moved, locomotor task time 20.40.40.9-0.90.50.90.80.4-0.8-0.00.9-0.70.5-0.50.00.70.4
Vertical activity count, locomotor time 20.10.10.4-0.4-0.00.50.7-0.1-0.2-0.30.4-0.30.00.20.00.0-0.0
Weight adjusted by age4.14.66.7-2.42.22.42.62.3-2.02.32.31.12.2-2.20.02.42.3
Seeking ratio, delayed vs. immediate footshock0.50.51.0-1.00.80.80.90.8-0.90.60.60.30.7-0.80.00.70.7
Locomotion in novel chamber0.50.61.1-0.80.90.70.40.9-0.90.70.7-0.30.8-1.00.01.00.9
Locomotion in novel chamber post-restriction0.50.61.3-1.00.61.11.10.7-0.80.50.9-0.20.8-0.80.00.80.8
Progressive ratio4.45.17.2-2.62.52.72.42.4-2.61.52.2-1.12.4-2.70.02.52.3
Food seeking constrained by brief footshock0.00.00.1-0.0-0.0-0.00.1-0.20.0-0.3-0.0-0.1-0.10.10.0-0.1-0.1
Seeking ratio, punishment vs. effort3.64.46.82.3-2.3-2.4-1.9-2.32.4-1.5-1.91.1-2.32.60.0-2.4-2.2
Run reversals in cocaine runway, females0.20.21.5-0.3-0.10.3-0.1-0.2-0.1-0.6-0.2-1.20.1-0.10.00.1-0.2
Run reversals in cocaine runway, males0.70.61.8-0.11.30.30.10.9-1.01.20.30.60.9-0.80.00.81.0
Latency to leave start box in cocaine runway0.20.21.00.20.5-0.2-0.00.3-0.10.71.01.00.3-0.10.00.20.4
Latency to leave start box in cocaine runway, F0.30.31.00.9-0.2-0.8-0.7-0.40.50.0-0.11.0-0.40.60.0-0.5-0.3
Latency to leave start box in cocaine runway, M1.11.12.7-0.91.10.90.71.1-1.21.01.6-0.11.1-1.20.01.21.1
Cd content in liver0.30.31.4-0.30.50.70.10.4-0.6-0.30.3-1.20.6-0.70.00.70.4
Co content in liver1.21.43.5-1.71.01.61.91.0-1.10.51.5-0.71.0-1.20.01.20.9
Cu content in liver3.64.37.91.6-2.3-1.9-1.6-2.52.2-2.8-1.9-1.7-2.32.20.0-2.1-2.5
Fe content in liver0.50.52.3-0.90.60.90.90.4-0.6-0.20.8-1.50.5-0.70.00.60.4
K content in liver0.20.20.60.6-0.5-0.8-0.7-0.20.4-0.0-0.10.8-0.40.30.0-0.4-0.4
Mg content in liver1.81.94.61.7-1.3-2.0-1.4-1.01.50.0-1.22.1-1.31.40.0-1.4-1.1
Mn content in liver1.01.19.31.3-0.5-1.2-0.1-0.10.81.1-0.63.1-0.50.70.0-0.7-0.2
Na content in liver0.10.21.50.10.1-0.2-1.20.2-0.20.10.50.40.2-0.30.00.10.1
Rb content in liver0.81.01.91.4-1.1-1.0-1.0-1.01.2-0.8-0.90.0-1.11.20.0-1.2-1.1
Se content in liver0.91.07.31.0-0.5-1.4-1.0-0.20.80.8-0.62.7-0.70.60.0-0.7-0.3
Sr content in liver0.80.71.9-0.50.90.70.60.9-0.71.10.81.40.9-0.80.00.81.0
Zn content in liver0.20.21.70.20.0-0.10.40.10.10.40.51.30.0-0.00.0-0.00.1