Hub : Genes

Cox7a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000050015 0.42 0.14 0.0e+00 0.36 0.36 0.37 0.36 6.1e-42 2.2e-42 8.4e-43 3.0e-42
2 Adipose mRNA stability ENSRNOG00000050015 0.06 0.04 4.1e-07 0.03 0.03 0.02 0.02 2.8e-04 6.1e-04 1.1e-03 8.6e-04
3 BLA gene expression ENSRNOG00000050015 0.18 0.08 5.2e-13 0.2 0.22 0.19 0.22 4.3e-11 4.8e-12 2.9e-10 9.9e-12
4 BLA intron excision ratio chr1:85425012:85442631 0.07 0.05 4.8e-04 0.04 0.03 0.04 0.03 4.0e-03 9.2e-03 3.3e-03 1.1e-02
5 Brain gene expression ENSRNOG00000050015 0.07 0.04 2.9e-09 0.1 0.04 0.09 0.03 9.9e-10 1.3e-04 1.5e-08 1.4e-03
6 Brain intron excision ratio chr1:85425012:85442631 0.15 0.1 1.9e-13 0.16 0.05 0.15 0.08 8.7e-15 1.2e-05 1.9e-13 8.2e-08
7 Brain mRNA stability ENSRNOG00000050015 0.13 0.07 0.0e+00 0.18 0.1 0.19 0.15 2.0e-16 2.4e-09 5.3e-17 1.6e-13
8 Eye mRNA stability ENSRNOG00000050015 0.31 0.18 2.0e-03 0.09 0 0.03 -0.02 1.6e-02 2.9e-01 1.1e-01 8.8e-01
9 IL gene expression ENSRNOG00000050015 0.26 0.16 4.2e-05 0.11 0.04 0.09 0.04 1.1e-03 3.3e-02 2.9e-03 3.2e-02
10 LHb gene expression ENSRNOG00000050015 0.26 0.15 4.3e-05 0.18 0.04 0.13 0.17 4.8e-05 3.8e-02 6.0e-04 8.9e-05
11 PL gene expression ENSRNOG00000050015 0.12 0.06 4.0e-15 0.21 0.2 0.2 0.2 1.3e-15 4.5e-15 1.7e-15 1.5e-15
12 PL intron excision ratio chr1:85425012:85442631 0.04 0.03 1.4e-04 0.04 0.05 0.05 0.05 6.7e-04 6.8e-05 1.6e-04 2.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.20.81.30.9-0.6-1.0-1.1-1.0-0.8-0.8-0.8-0.9-0.7-0.9-1.0
BMI without tail0.10.10.3-0.30.10.30.50.30.40.40.5-0.10.40.20.3
Body weight2.611.114.5-3.23.83.33.32.83.33.23.63.53.43.23.2
Epididymis fat weight0.10.20.6-0.30.70.20.10.00.30.20.80.70.40.10.2
Glucose0.20.20.40.6-0.1-0.5-0.4-0.6-0.6-0.6-0.1-0.2-0.5-0.6-0.5
Heart weight0.20.30.5-0.70.50.50.60.70.30.40.60.50.30.50.5
Left kidney weight2.46.910.0-2.33.22.52.22.12.82.52.83.22.92.32.4
Right kidney weight4.813.616.0-3.44.03.63.43.33.93.64.04.03.83.53.5
Tail length5.115.419.3-3.83.83.94.43.74.04.04.23.74.03.74.0
Length with tail8.531.134.9-5.55.65.65.95.25.55.55.85.65.55.45.6
Length without tail5.311.614.4-3.33.83.33.22.83.43.33.63.83.63.33.3
Liver weight, left0.50.71.21.1-0.7-0.9-0.9-1.0-0.6-0.9-0.6-0.8-0.6-1.0-0.9
Liver weight, right0.10.20.60.6-0.8-0.4-0.3-0.6-0.2-0.3-0.3-0.7-0.0-0.2-0.4
Parametrial fat weight0.20.30.70.8-0.4-0.6-0.8-0.7-0.1-0.40.3-0.40.1-0.6-0.6
Retroperitoneal fat weight1.55.07.22.5-1.7-2.4-2.3-2.7-2.2-2.4-1.5-1.8-2.2-2.4-2.4
Intraocular pressure0.00.00.1-0.2-0.00.0-0.10.3-0.3-0.1-0.3-0.0-0.20.20.0
Extensor digitorum longus weight0.10.61.11.0-0.2-0.8-0.7-1.1-0.8-0.9-0.5-0.4-0.8-1.0-0.8
Soleus weight0.10.41.20.6-0.4-0.6-0.7-1.1-0.5-0.7-0.4-0.5-0.4-0.6-0.6
Tibialis anterior weight0.00.20.30.50.3-0.3-0.3-0.5-0.4-0.4-0.20.2-0.4-0.5-0.4
Tibia length2.77.711.4-2.63.22.72.82.32.62.63.43.12.72.52.7
Number of licking bursts3.54.25.22.1-1.7-2.1-2.0-2.3-2.1-2.1-2.0-1.7-2.1-2.3-2.1
Food consumed during 24 hour testing period0.80.91.3-1.10.81.01.00.91.01.01.00.81.01.01.0
Times rat made contact with spout0.80.91.61.1-0.2-0.9-1.1-1.3-1.0-1.1-0.8-0.2-0.9-1.1-1.0
Mean time between licks in bursts0.00.10.1-0.1-0.40.10.20.20.30.20.2-0.40.30.10.1
Mean num. licks in bursts1.21.41.8-1.11.31.21.11.21.11.11.11.31.11.31.2
Std. dev. time between licks in bursts0.60.71.7-0.9-0.30.71.11.30.81.00.7-0.30.90.90.8
Water consumed over 24 hours0.40.40.7-0.60.80.60.50.30.70.60.70.80.70.60.6
Indifference point 0 sec0.10.10.3-0.3-0.00.30.3-0.00.50.40.2-0.10.60.40.4
Indifference point AUC0.40.50.70.8-0.7-0.8-0.8-0.8-0.6-0.5-0.6-0.8-0.6-0.3-0.8
Indifference point function ln k0.40.61.1-1.00.70.90.81.00.60.70.60.80.60.70.8
Indifference point function log k0.40.61.1-1.00.70.90.81.00.60.70.60.80.60.70.8
Delay discounting total patch changes 0 sec0.20.20.6-0.50.20.50.50.20.70.60.40.10.80.50.6
Delay discounting total patch changes 12 sec0.10.10.4-0.0-0.60.10.20.30.10.30.0-0.70.20.30.2
Delay discounting total patch changes 18 sec0.10.10.50.20.1-0.2-0.3-0.7-0.0-0.2-0.00.00.1-0.2-0.2
Delay discounting total patch changes 24 sec0.80.91.3-0.91.10.91.10.80.90.91.11.11.00.70.9
Delay discounting total patch changes 6 sec0.00.10.30.1-0.20.00.0-0.30.40.30.1-0.20.50.20.1
Delay discounting time to switch 0 sec0.50.81.30.9-1.2-0.8-0.8-0.5-0.8-0.8-1.0-1.1-0.8-1.0-0.8
Delay discounting water rate 0 sec0.71.12.11.0-1.0-1.1-1.1-1.4-1.0-1.0-1.0-1.0-0.8-0.9-1.1
Delay discounting water rate 12 sec0.71.01.9-0.71.30.71.20.60.90.81.41.31.00.80.8
Delay discounting water rate 18 sec0.10.20.40.4-0.5-0.5-0.2-0.6-0.5-0.5-0.0-0.5-0.4-0.4-0.5
Delay discounting water rate 24 sec0.00.00.2-0.10.30.00.3-0.1-0.1-0.10.10.40.1-0.20.1
Delay discounting water rate 6 sec1.01.52.0-1.21.31.01.10.91.41.21.41.41.41.01.1
Locomotor activity0.40.71.00.9-0.8-0.8-1.0-1.0-0.8-0.8-0.6-0.9-0.7-0.7-0.8
Locomotor testing distance0.40.60.90.8-0.6-0.8-1.0-0.9-0.9-0.8-0.6-0.6-0.8-0.8-0.8
Locomotor testing rearing2.13.35.02.0-1.2-1.9-1.7-2.2-1.9-1.9-1.6-1.2-1.8-2.2-1.9
Light reinforcement 10.10.20.50.4-0.2-0.5-0.5-0.7-0.2-0.3-0.5-0.3-0.3-0.2-0.4
Light reinforcement 22.83.64.61.8-2.0-2.0-2.1-1.8-1.8-1.8-2.0-2.0-1.9-1.7-2.0
Reaction time number correct0.00.10.30.20.1-0.3-0.3-0.6-0.2-0.20.20.1-0.1-0.2-0.3
Reaction time mean minus median0.40.61.3-0.50.80.70.50.21.10.70.90.91.00.60.7
Reaction time mean minus median AUC0.91.12.4-0.71.30.80.80.31.50.91.31.41.40.70.9
Reaction time num false alarms1.01.42.21.3-0.9-1.2-1.2-1.5-1.1-1.2-1.0-0.9-1.0-1.4-1.2
Reaction time num false alarms AUC1.21.72.41.3-1.1-1.4-1.5-1.6-1.2-1.3-1.1-1.1-1.2-1.4-1.4
Reaction time trials correct on left0.00.10.30.20.1-0.3-0.3-0.6-0.2-0.20.20.1-0.1-0.2-0.3
Reaction time trials on left0.10.10.40.20.1-0.4-0.3-0.6-0.2-0.30.10.1-0.1-0.2-0.4
Reaction time mean0.20.20.7-0.20.80.20.0-0.10.60.20.60.90.40.10.2
Reaction time mean AUC0.10.10.4-0.00.60.1-0.2-0.30.50.10.50.60.3-0.00.0
Median of all reaction times0.10.10.30.00.6-0.0-0.2-0.30.2-0.10.30.50.0-0.1-0.1
Reaction time omissions0.10.10.50.4-0.0-0.3-0.3-0.70.2-0.30.1-0.00.1-0.5-0.3
Reaction time false alarm rate0.60.91.11.0-0.9-0.9-1.0-1.0-0.9-1.0-0.9-0.9-0.9-1.1-0.9
Reaction time premature initiation rate0.10.10.4-0.5-0.20.30.30.40.20.40.2-0.20.30.70.3
Reaction time premature initiations0.00.10.3-0.4-0.10.10.1-0.10.10.20.2-0.10.20.50.1
Std. dev. reaction times0.60.81.8-0.61.30.70.60.21.20.71.11.31.10.60.7
Reaction time trials completed0.10.10.40.20.1-0.4-0.3-0.6-0.2-0.30.10.1-0.1-0.2-0.4
Reaction time trials AUC0.10.10.50.30.1-0.5-0.5-0.7-0.2-0.40.00.0-0.2-0.3-0.5
Social response proportion2.42.73.7-1.90.91.81.61.91.61.71.31.11.61.91.8
Social responses0.81.02.5-1.20.11.00.50.91.21.20.40.31.21.61.1
Social time2.73.64.6-2.11.92.01.81.71.91.91.72.01.82.02.0
Conditioned locomotion0.50.71.20.6-1.1-0.7-0.5-0.7-1.0-0.7-0.8-1.1-1.0-0.5-0.7
Cocaine response after cond. corrected0.10.10.20.4-0.5-0.2-0.10.1-0.1-0.1-0.5-0.5-0.1-0.2-0.2
Cocaine response after cond. not corrected0.00.00.10.3-0.3-0.1-0.10.20.20.1-0.3-0.20.1-0.1-0.1
Cocaine response before conditioning1.31.62.2-1.21.31.20.91.01.41.21.41.51.41.31.2
Saline control response0.00.00.1-0.1-0.00.10.20.2-0.10.1-0.30.0-0.10.10.1
Condit. Reinf. active minus inactive responses1.92.34.3-1.61.01.61.62.11.51.70.91.01.61.61.6
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.1-0.00.20.5-0.2-0.0-0.5-0.1-0.1-0.2-0.0
Condit. Reinf. active responses3.95.56.7-2.51.92.42.32.62.42.51.92.02.52.42.5
Condit. Reinf. inactive responses4.55.67.0-2.51.92.42.22.12.72.52.22.02.62.52.4
Condit. Reinf. lever presses7.910.912.3-3.32.93.43.53.43.33.43.12.93.43.43.5
Condit. Reinf. lever reinforcers received4.15.76.8-2.52.12.52.42.62.42.61.92.12.52.52.5
Pavlov. Cond. lever latency5.27.17.52.7-2.5-2.7-2.7-2.7-2.7-2.7-2.6-2.5-2.7-2.7-2.7
Pavlov. Cond. magazine entry latency3.13.54.2-2.01.41.91.92.02.02.01.81.41.92.12.0
Pavlov. Cond. change in total contacts8.812.213.7-3.63.43.53.63.73.53.53.33.33.53.43.6
Pavlov. Cond. index score5.47.07.4-2.72.42.72.72.72.72.72.72.52.72.72.7
Pavlov. Cond. latency score5.16.46.8-2.62.32.62.62.62.62.62.52.32.62.62.6
Pavlov. Cond. lever contacts4.76.57.1-2.52.52.62.72.62.52.62.62.52.62.42.6
Pavlov. Cond. magazine entry number4.05.05.82.2-2.3-2.2-2.3-2.3-2.1-2.2-2.4-2.3-2.1-2.1-2.2
Pavlov. Cond. intertrial magazine entries1.21.63.21.3-1.0-1.3-1.6-1.8-1.0-1.3-1.2-0.9-1.0-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.5.26.87.4-2.62.42.62.72.62.62.62.72.52.62.62.6
Pavlov. Cond. response bias5.37.48.0-2.72.72.72.82.82.72.72.82.72.72.52.7
Conditioned reinforcement - actives0.10.10.20.4-0.3-0.3-0.0-0.4-0.5-0.5-0.3-0.3-0.4-0.5-0.3
Conditioned reinforcement - inactives0.60.61.1-1.00.40.81.10.70.80.90.80.40.70.90.9
Conditioned locomotion2.12.63.21.5-1.6-1.6-1.6-1.4-1.8-1.6-1.7-1.6-1.8-1.2-1.6
Intermittent access intake day 1-15 change2.22.23.5-1.41.81.41.41.11.61.41.51.91.61.21.4
Intermittent access intake escalation2.12.13.4-1.41.81.41.41.11.51.31.41.81.61.11.4
Intermittent access intake escalation 21.71.72.0-1.31.41.41.41.21.31.21.31.41.40.91.4
Intermitt. access day 1 inactive lever presses3.74.05.3-2.21.32.01.72.22.32.22.11.42.32.02.0
Intermitt. access day 15 inactive lever presses0.50.50.9-0.80.20.70.80.90.90.80.70.20.90.30.8
Intermitt. access escalation Index0.10.10.30.2-0.1-0.2-0.2-0.3-0.5-0.3-0.5-0.1-0.5-0.2-0.3
Intermittent access day 1 total infusions2.12.43.21.5-1.4-1.6-1.3-1.5-1.8-1.7-1.6-1.4-1.8-1.6-1.6
Intermittent access day 15 total infusions0.00.00.2-0.00.2-0.00.3-0.0-0.2-0.3-0.20.1-0.2-0.40.0
Intermittent access terminal intake (last 3 days)0.20.20.50.2-0.3-0.30.1-0.2-0.6-0.6-0.5-0.4-0.6-0.7-0.3
Intermittent access total infusions0.40.40.80.5-0.5-0.6-0.3-0.5-0.9-0.9-0.7-0.5-0.9-0.9-0.6
Intermittent access day 1 locomotion0.90.91.20.7-1.1-0.9-0.9-0.7-1.1-1.0-1.1-1.1-1.0-0.8-0.9
Intermittent access day 15 total locomotion0.00.00.1-0.20.2-0.1-0.2-0.2-0.2-0.3-0.20.1-0.10.0-0.1
Intermittent access total locomotion1.01.21.40.9-1.1-1.1-1.1-0.9-1.2-1.2-1.2-1.2-1.1-0.9-1.1
Intermittent access standard deviation5.66.06.8-2.52.42.52.62.42.42.42.42.42.42.42.5
Cocaine induced anxiety0.60.60.9-0.80.50.80.70.90.80.90.90.50.80.90.8
Post-drug Anxiety0.10.10.50.2-0.7-0.00.10.30.00.10.1-0.70.1-0.1-0.0
Baseline Anxiety1.31.41.81.3-1.4-1.2-1.1-1.2-1.0-1.1-1.2-1.4-1.0-1.3-1.2
Lifetime Intake0.60.71.20.8-0.5-0.8-0.6-0.7-1.0-1.1-0.8-0.6-1.0-1.1-0.8
Incentive Sensitization - Responses0.10.10.30.10.0-0.1-0.10.2-0.5-0.4-0.50.0-0.4-0.5-0.1
Incentive Sensitization - Breakpoint0.10.10.30.10.1-0.1-0.10.1-0.5-0.4-0.40.1-0.3-0.6-0.1
Progressive ratio test 1 active lever presses0.40.40.7-0.80.80.70.70.70.40.40.60.80.50.70.6
Progressive ratio test 1 breakpoint0.90.91.3-1.11.00.90.91.10.70.70.81.00.71.10.9
Progressive ratio test 1 inactive lever presses0.50.50.9-1.00.40.70.80.80.60.80.50.40.70.80.8
Progressive ratio test 2 active lever presses0.10.10.2-0.30.30.20.40.4-0.2-0.1-0.10.3-0.1-0.10.2
Progressive ratio test 2 breakpoint0.00.00.1-0.20.20.10.30.3-0.3-0.2-0.20.2-0.2-0.10.1
Progressive ratio test 2 inactive lever presses1.11.23.0-1.50.41.21.41.70.61.10.50.30.71.41.2
Total sessions with >9 infusions1.31.52.11.4-0.9-1.3-1.3-1.4-1.1-1.4-1.0-0.9-1.0-1.4-1.3
Short access day 1 total inactive lever presses0.20.30.6-0.70.00.50.70.60.20.60.20.00.20.80.6
Short access day 10 total inactive lever presses1.71.93.3-1.70.81.51.21.81.21.40.90.91.31.61.5
Short access day 1 total infusions0.10.10.30.5-0.1-0.3-0.2-0.4-0.4-0.5-0.3-0.1-0.4-0.6-0.3
Short access day 10 total infusions0.50.51.00.7-0.4-0.7-0.8-0.6-0.7-1.0-0.5-0.4-0.7-0.9-0.8
Short access total infusions1.11.21.81.2-0.7-1.1-1.1-1.1-1.2-1.3-1.0-0.7-1.1-1.2-1.2
Short access day 1 locomotion0.50.51.30.8-0.4-0.9-1.2-1.2-0.3-0.7-0.3-0.4-0.4-0.6-0.9
Short access day 10 total locomotion0.70.81.5-1.10.50.80.61.10.90.90.80.51.01.20.8
Short access total locomotion0.90.91.20.9-1.1-1.0-1.1-0.9-0.9-1.0-0.8-1.1-0.8-0.6-1.0
Compulsive drug intake0.10.10.3-0.10.10.30.6-0.10.20.30.10.20.2-0.00.3
One hour access (0.3 mA shock)1.01.21.7-1.21.11.21.31.10.90.91.01.01.01.01.2
One hour access (shock baseline)0.00.00.1-0.30.20.20.30.40.00.10.10.10.00.20.2
Number of responses in last shaping day0.10.10.3-0.2-0.20.10.40.3-0.40.1-0.4-0.2-0.30.60.1
Context. condit. distance diff. score0.00.00.0-0.00.1-0.1-0.1-0.1-0.2-0.1-0.20.1-0.2-0.2-0.1
Locomotion velocity, session 10.60.71.00.8-0.5-0.8-1.0-0.7-1.0-0.9-0.7-0.5-1.0-0.7-0.9
Locomotion distance, session 10.50.61.0-0.91.00.80.70.70.50.70.71.00.50.80.8
Locomotion velocity, session 20.50.61.30.7-1.1-0.7-0.8-0.4-0.8-0.6-1.1-1.0-0.7-0.5-0.7
Locomotion distance, session 21.21.82.31.2-1.2-1.4-1.5-1.4-1.4-1.4-1.4-1.2-1.4-1.2-1.4
Locomotion velocity, session 30.30.30.50.7-0.4-0.6-0.7-0.6-0.5-0.6-0.7-0.4-0.5-0.7-0.6
Locomotion distance, session 32.93.24.0-2.01.61.81.71.91.91.91.31.51.91.91.9
Stereotopy head waving bouts, day 30.70.81.21.1-1.1-0.9-0.9-1.0-0.8-0.9-0.7-1.0-0.7-0.8-0.9
Stereotopy head waving duration, day 31.51.92.51.5-1.6-1.4-1.3-1.5-1.3-1.4-1.0-1.5-1.2-1.3-1.4
Locomotion velocity, session 70.30.30.5-0.70.70.50.40.40.40.50.50.70.50.60.5
Locomotion distance, session 70.10.20.5-0.40.70.40.20.20.30.30.20.70.40.40.4
Stereotopy head waving bouts, day 70.91.01.51.0-1.1-1.0-0.7-0.9-1.2-1.0-0.8-1.1-1.1-1.0-1.0
Stereotopy head waving duration, day 72.32.83.31.7-1.8-1.7-1.4-1.6-1.8-1.7-1.5-1.8-1.8-1.7-1.7
Locomotion velocity, session 84.04.85.42.1-2.0-2.2-2.3-2.3-2.3-2.2-2.3-2.1-2.2-2.1-2.2
Locomotion distance, session 80.60.91.40.8-0.7-1.0-1.0-1.0-1.0-1.0-1.2-0.7-1.0-1.0-1.0
Degree of sensitization distance0.60.61.00.9-0.4-0.8-0.8-1.0-0.8-0.9-0.5-0.3-0.7-0.8-0.8
Degree of sensitization stereotypy1.21.31.51.1-1.1-1.2-0.8-1.1-1.2-1.2-0.9-1.2-1.2-1.2-1.1
Condit. Reinf. active minus inactive responses0.20.20.40.4-0.7-0.5-0.5-0.2-0.5-0.4-0.4-0.6-0.5-0.4-0.5
Condit. Reinf. active-inactive response ratio0.20.20.80.6-0.8-0.4-0.3-0.3-0.3-0.3-0.2-0.9-0.2-0.4-0.4
Condit. Reinf. active responses2.22.63.41.4-1.8-1.6-1.7-1.3-1.8-1.6-1.6-1.7-1.8-1.5-1.7
Condit. Reinf. inactive responses2.22.64.01.3-1.5-1.6-1.8-1.4-1.9-1.7-1.8-1.4-2.0-1.4-1.6
Incentive salience index mean0.20.20.60.3-0.8-0.4-0.5-0.1-0.4-0.3-0.5-0.7-0.4-0.4-0.4
Condit. Reinf. lever presses0.00.10.2-0.3-0.40.1-0.10.40.20.3-0.2-0.30.20.20.1
Time in familiar zone, hab. session 10.30.30.8-0.40.90.50.50.60.30.40.50.90.40.50.5
Time in novel zone, hab. session 11.21.22.41.0-1.6-1.1-0.8-1.0-0.8-1.0-1.0-1.5-0.9-1.1-1.0
Total zone transitions, hab. session 10.00.00.1-0.20.00.00.10.3-0.30.0-0.10.0-0.30.10.0
Total locomotion distance, hab. session 11.31.93.1-1.50.71.41.61.81.21.51.20.81.21.61.5
Locomotion velocity, hab. session 10.81.11.9-1.20.51.11.11.40.91.20.90.60.91.31.1
Time in familiar zone, hab. session 22.22.33.4-1.60.91.61.51.61.71.71.20.91.71.91.6
Time in novel zone, hab. session 21.51.52.21.3-0.8-1.3-1.1-1.3-1.3-1.4-0.9-0.8-1.4-1.5-1.3
Total zone transitions, hab. session 23.14.04.52.0-2.1-2.0-1.8-1.9-2.1-1.9-2.0-2.1-2.1-1.9-2.0
Total locomotion distance, hab. session 20.10.10.60.2-0.8-0.30.0-0.1-0.3-0.2-0.2-0.7-0.3-0.1-0.2
Locomotion velocity, hab. session 20.20.20.80.3-0.9-0.4-0.2-0.3-0.4-0.3-0.4-0.7-0.4-0.2-0.4
Novel to familiar place preference ratio0.10.10.3-0.30.40.40.60.20.50.40.40.30.40.10.4
Novelty place preference0.10.10.2-0.20.30.20.40.10.40.20.30.30.30.00.3
Time in novel zone, NPP test0.00.00.00.00.20.00.2-0.10.10.00.10.10.1-0.20.0
Total zone transitions, NPP test0.10.10.20.2-0.1-0.3-0.4-0.4-0.5-0.3-0.3-0.1-0.5-0.1-0.3
Total locomotion distance, NPP test2.43.33.9-1.91.61.91.91.71.71.91.81.71.82.01.9
Locomotion velocity, NPP test2.63.74.4-2.01.62.02.01.81.82.02.01.71.92.12.0
Pavlov. Cond. lever latency0.20.30.6-0.40.80.50.60.50.30.30.80.70.30.40.4
Pavlov. Cond. magazine entry latency0.40.50.80.8-0.9-0.7-0.5-0.9-0.6-0.7-0.7-0.8-0.7-0.8-0.7
Pavlov. Cond. change in total contacts0.30.30.60.4-0.8-0.5-0.5-0.3-0.4-0.3-0.8-0.8-0.4-0.5-0.5
Pavlov. Cond. index score0.60.71.30.9-1.1-0.8-0.8-0.9-0.6-0.7-0.9-1.1-0.7-0.8-0.8
Pavlov. Cond. latency score0.30.40.90.6-0.9-0.6-0.6-0.5-0.4-0.4-0.8-0.8-0.4-0.5-0.5
Pavlov. Cond. lever contacts0.10.10.2-0.2-0.40.20.00.10.40.3-0.4-0.40.30.30.2
Pavlov. Cond. magazine entry number0.60.71.0-0.91.00.80.60.90.80.80.70.90.80.90.8
Pavlov. Cond. intertrial magazine entries0.70.91.40.8-0.7-0.9-1.0-0.3-1.1-0.9-1.2-0.9-1.1-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.61.0-1.3-0.9-0.8-1.0-0.7-0.8-1.0-1.2-0.8-0.9-0.9
Pavlov. Cond. response bias0.20.20.50.5-0.7-0.4-0.3-0.5-0.2-0.3-0.5-0.7-0.3-0.4-0.4
Bone: apparent density0.50.81.9-0.71.20.80.60.31.00.81.41.21.00.80.7
Bone surface1.52.63.7-1.61.81.61.31.01.71.61.91.91.71.61.5
Bone volume1.42.43.9-1.41.91.51.30.91.61.41.92.01.61.41.4
Bone: connectivity density0.20.30.6-0.50.60.50.10.00.80.50.80.70.80.60.4
Bone: cortical apparent density2.12.83.51.6-1.3-1.7-1.9-1.8-1.7-1.8-1.7-1.3-1.7-1.7-1.7
Bone: cortical area1.32.02.6-1.31.51.51.41.11.51.51.31.41.61.41.5
Bone: cortical porosity1.61.72.61.2-1.6-1.4-1.4-1.5-1.0-1.3-1.1-1.5-1.0-1.2-1.3
Bone: cortical porosity2.12.33.01.4-1.7-1.6-1.6-1.7-1.3-1.5-1.3-1.6-1.2-1.4-1.5
Bone: cortical thickness0.30.40.6-0.50.70.70.80.40.70.60.60.60.80.60.7
Bone: cortical thickness0.80.91.11.0-0.8-1.0-1.0-1.0-1.0-1.0-0.8-0.9-0.9-0.9-1.0
Bone: cortical tissue density2.53.24.01.7-1.4-1.8-2.0-1.9-1.8-1.9-1.8-1.4-1.8-1.8-1.9
Bone: elastic displacement0.00.00.10.10.1-0.00.0-0.3-0.0-0.10.1-0.10.00.1-0.0
Bone: elastic work1.82.43.1-1.51.51.61.71.41.51.51.81.41.51.61.6
Bone: endosteal estimation1.73.64.1-2.01.82.01.91.81.82.01.91.81.82.02.0
Bone: endosteal perimeter1.63.43.9-2.01.71.91.81.91.82.01.61.61.81.91.9
Bone: final force1.62.53.1-1.61.51.61.61.41.61.61.71.51.81.61.6
Bone: final moment2.03.33.9-1.81.81.91.81.61.91.81.91.82.01.81.9
Bone: marrow area1.83.84.2-2.01.82.01.91.91.92.02.01.81.92.02.0
Bone: maximum diameter1.42.63.5-1.51.61.61.61.21.81.71.61.51.91.51.6
Bone: maximum force2.64.55.3-2.12.12.12.21.92.12.12.32.12.22.12.1
Bone: maximum moment3.15.45.9-2.32.32.42.42.22.32.32.42.32.42.32.4
Bone: minimum diameter3.56.47.6-2.72.22.62.72.62.52.72.32.22.52.62.6
Bone: periosteal estimation2.14.34.6-2.12.12.12.11.82.12.12.12.02.12.12.1
Bone: periosteal perimeter1.52.53.1-1.71.41.71.71.71.51.71.31.31.51.81.7
Bone: post-yield work1.82.42.8-1.71.51.61.61.51.61.61.61.41.61.51.6
Bone: stiffness1.42.22.4-1.51.31.51.51.51.41.41.61.51.51.51.5
Bone: tissue strength3.53.34.0-1.81.71.82.01.62.01.81.91.72.01.61.9
Bone: trabecular number1.42.13.7-1.41.61.41.21.11.51.41.91.71.51.31.3
Bone: trabecular spacing0.30.30.8-0.50.10.60.90.70.60.70.30.00.60.60.7
Bone: trabecular thickness0.10.20.40.50.3-0.4-0.4-0.6-0.3-0.50.10.3-0.3-0.6-0.4
Bone: trabecular tissue density2.43.34.12.0-1.4-1.8-1.8-1.9-2.0-2.0-1.6-1.4-2.0-1.9-1.9
Breakpoint value in progressive ratio session2.12.34.6-1.90.71.71.72.01.21.50.80.61.32.11.7
Distance traveled before self-admin0.10.10.4-0.30.10.40.50.7-0.3-0.0-0.30.1-0.30.10.3
Distance traveled after self-admin4.34.85.7-2.32.02.32.42.22.12.22.12.12.02.32.3
Delta time in closed arm before/after self-admin2.62.63.5-1.61.81.61.51.51.61.51.91.71.71.41.5
Delta time in open arm before/after self-admin1.00.91.51.2-0.8-1.1-1.0-1.2-0.5-0.7-1.1-0.8-0.6-1.1-1.0
Diff in mean of infusions in LGA sessions0.30.31.0-0.0-0.9-0.2-0.10.3-0.7-0.3-0.9-1.0-0.70.1-0.2
Extinction: sum of active levers before priming3.53.64.5-2.01.91.91.42.11.91.81.71.92.02.11.9
Active lever presses in extinction session 62.92.83.7-1.91.41.81.41.91.61.71.41.41.71.91.8
Delta distance traveled before/after self-admin4.85.26.6-2.22.22.22.11.82.62.42.32.22.52.32.2
Delta ambulatory time before/after self-admin5.25.67.1-2.32.42.22.11.72.72.42.62.42.62.52.2
Time in closed arm before self-admin2.42.73.51.8-1.7-1.6-1.2-1.5-1.8-1.7-1.5-1.6-1.9-1.9-1.6
Time in closed arm after self-admin0.20.20.8-0.4-0.10.50.60.9-0.10.30.6-0.0-0.10.50.4
Time in open arm before self-admin4.65.06.0-2.32.12.21.82.12.52.22.32.12.52.42.2
Time in open arm after self-admin0.91.02.3-0.81.20.80.50.31.51.00.71.11.50.80.8
Sum of active levers in priming session hrs 5-60.20.20.4-0.50.30.40.20.60.30.30.20.40.40.50.4
Time to tail flick, vehicle, before self-admin1.01.01.40.9-1.0-1.0-1.0-0.9-1.2-1.0-1.2-1.0-1.0-0.4-1.0
Time to tail flick, vehicle, after self-admin0.10.20.4-0.3-0.50.30.50.6-0.00.4-0.1-0.50.10.60.3
Time to tail flick, test, before self-admin0.50.52.00.8-0.0-0.7-0.3-1.2-0.5-0.8-0.3-0.0-0.5-1.4-0.7
Time to tail flick, test, after self-admin0.10.10.60.20.0-0.2-0.2-0.80.1-0.10.10.00.00.3-0.2
Delta time to tail flick, vehicle, before/after SA0.80.81.1-0.90.60.81.00.81.01.01.10.51.00.80.9
Delta time to tail flick, test, before/after SA0.20.20.30.2-0.6-0.3-0.6-0.4-0.2-0.2-0.4-0.6-0.20.5-0.3
Ambulatory time before self-admin0.10.10.3-0.2-0.20.20.20.5-0.3-0.0-0.4-0.1-0.30.10.2
Ambulatory time after self-admin7.88.610.6-3.22.73.02.92.82.92.92.92.82.83.33.0
Total heroin consumption0.50.61.5-1.00.40.90.71.10.50.60.20.30.51.20.9
Area under the delay curve0.40.51.2-0.70.10.71.10.90.60.70.70.10.60.60.8
Delay disc. indifference point, 0s delay0.20.20.9-0.70.30.50.90.7-0.20.30.20.3-0.30.50.5
Delay disc. indifference point, 16s delay1.31.32.6-1.20.21.21.61.51.01.21.10.11.11.21.3
Delay disc. indifference point, 2s delay1.01.12.0-1.21.11.11.40.90.81.00.91.00.80.91.1
Delay disc. indifference point, 24s delay2.52.53.3-1.71.11.61.61.71.71.71.51.21.81.51.6
Delay disc. indifference point, 4s delay0.10.10.30.1-0.5-0.00.40.0-0.2-0.00.0-0.6-0.2-0.2-0.0
Delay disc. indifference point, 8s delay0.20.20.5-0.40.30.40.50.40.60.40.70.20.60.30.4
Delay discount exponential model param0.60.61.30.8-0.2-0.8-1.1-0.9-0.8-0.8-0.8-0.2-0.8-0.6-0.8
Delay discount hyperbolic model param0.40.41.10.7-0.2-0.7-1.1-0.7-0.6-0.7-0.7-0.1-0.6-0.5-0.7
Fecal boli incidents, locomotor time 11.92.14.01.0-2.0-1.3-1.5-0.8-1.5-1.3-1.8-2.0-1.6-0.8-1.3
Change in fecal boli incidents, locomotor task0.10.10.3-0.10.00.20.20.30.60.40.5-0.00.50.30.3
Time >=10cm from walls, locomotor time 10.00.00.10.3-0.3-0.2-0.0-0.1-0.1-0.20.3-0.2-0.2-0.3-0.2
Bouts of movement, locomotor time 10.80.91.7-1.10.71.01.31.10.50.90.50.70.31.21.1
Total resting periods, locomotor time 10.70.81.7-1.10.51.01.31.20.40.90.40.50.21.31.1
Rest time, locomotor task time 10.91.02.30.6-1.5-0.8-0.7-0.3-1.3-0.7-1.1-1.5-1.3-0.0-0.8
Distance moved, locomotor task time 10.10.10.40.10.70.0-0.1-0.40.2-0.10.10.60.5-0.6-0.0
Vertical activity count, locomotor time 11.81.93.5-1.21.61.21.20.81.71.41.41.61.90.81.2
Time >=10cm from walls, locomotor time 21.61.72.91.2-1.7-1.2-1.0-1.0-1.4-1.2-1.3-1.7-1.6-1.1-1.2
Bouts of movement, locomotor time 20.10.10.3-0.00.20.10.60.2-0.2-0.00.10.2-0.40.00.2
Total resting periods, locomotor time 20.00.00.20.1-0.1-0.00.30.0-0.3-0.1-0.1-0.1-0.4-0.1-0.0
Rest time, locomotor task time 20.40.41.40.4-1.2-0.5-0.5-0.2-0.8-0.4-0.8-1.1-0.7-0.1-0.5
Distance moved, locomotor task time 20.20.31.10.60.3-0.4-0.3-1.0-0.3-0.5-0.10.2-0.1-1.0-0.5
Vertical activity count, locomotor time 20.70.81.4-0.81.20.80.90.50.90.81.01.11.00.50.8
Weight adjusted by age0.10.10.30.20.5-0.1-0.1-0.50.3-0.00.50.30.3-0.2-0.1
Seeking ratio, delayed vs. immediate footshock1.31.52.4-1.11.31.21.61.21.21.21.31.41.00.61.2
Locomotion in novel chamber0.20.30.90.1-1.0-0.2-0.50.1-0.5-0.2-0.6-0.9-0.60.0-0.2
Locomotion in novel chamber post-restriction0.20.21.1-0.5-0.50.50.51.0-0.10.3-0.1-0.2-0.10.30.5
Progressive ratio0.00.00.1-0.2-0.20.1-0.00.30.20.2-0.0-0.20.1-0.20.1
Food seeking constrained by brief footshock3.34.15.2-2.31.72.22.02.32.12.01.81.82.01.82.2
Seeking ratio, punishment vs. effort0.60.71.0-0.90.80.91.00.80.80.80.80.90.81.00.9
Run reversals in cocaine runway, females0.40.41.5-0.51.20.50.30.00.80.50.71.00.60.40.4
Run reversals in cocaine runway, males0.20.20.50.7-0.5-0.5-0.7-0.40.2-0.30.3-0.30.2-0.5-0.5
Latency to leave start box in cocaine runway0.10.10.6-0.30.70.10.20.00.10.10.20.80.30.20.1
Latency to leave start box in cocaine runway, F0.00.00.20.10.2-0.3-0.2-0.50.0-0.10.00.20.1-0.1-0.2
Latency to leave start box in cocaine runway, M0.10.10.3-0.20.50.10.20.20.00.1-0.00.60.00.20.1
Cd content in liver0.10.10.4-0.10.60.10.1-0.30.0-0.00.50.50.10.10.1
Co content in liver0.40.51.00.7-0.7-0.8-1.0-0.7-0.4-0.5-0.7-0.8-0.4-0.6-0.8
Cu content in liver0.50.60.8-0.60.80.70.90.30.90.70.90.80.90.60.7
Fe content in liver0.00.00.00.1-0.2-0.1-0.2-0.0-0.2-0.1-0.1-0.2-0.1-0.1-0.1
K content in liver0.10.10.2-0.1-0.40.10.20.20.40.30.1-0.30.40.20.2
Mg content in liver0.60.61.50.8-1.2-0.7-0.7-0.8-0.4-0.6-0.8-1.2-0.4-0.7-0.7
Mn content in liver1.01.22.11.1-1.4-1.1-1.0-1.2-0.9-1.0-1.0-1.4-0.9-0.8-1.0
Na content in liver1.81.93.2-1.41.21.41.61.81.31.41.21.31.31.11.4
Rb content in liver0.10.10.40.2-0.6-0.2-0.1-0.2-0.1-0.1-0.4-0.5-0.1-0.2-0.2
Se content in liver8.410.210.83.2-3.3-3.2-3.3-3.2-3.1-3.2-3.2-3.2-3.0-3.1-3.2
Sr content in liver0.90.81.10.9-1.0-0.9-1.0-0.8-0.9-0.8-0.8-1.0-0.8-0.8-0.9
Zn content in liver0.10.10.30.4-0.5-0.4-0.5-0.4-0.1-0.2-0.4-0.5-0.1-0.4-0.4