Hub : Genes

ENSRNOG00000049931

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000049931	0.03	0.02	5.7e-03	0.01	0.01	0	0.01	2.2e-02	3.0e-02	1.8e-01	6.1e-02
2	Brain	gene expression	ENSRNOG00000049931	0.06	0.03	3.7e-04	0.05	0.04	0.04	0.05	3.4e-05	1.1e-04	9.0e-05	2.9e-05
3	NAcc	intron excision ratio	chr19:23915266:23917300	0.07	0.04	1.8e-03	0.02	0.02	0.01	0.02	5.9e-03	9.1e-03	1.1e-01	1.2e-02
4	PL	gene expression	ENSRNOG00000049931	0.08	0.04	9.6e-05	0.04	0.05	0.03	0.04	3.1e-04	8.7e-05	3.0e-03	3.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	2.1	6.8	15.1	3.9	-2.7	-0.3	-2.2
BMI without tail	0.3	0.6	0.9	0.9	-0.8	-0.6	-0.7
Body weight	0.0	0.2	0.4	0.2	-0.6	0.6	0.0
Epididymis fat weight	0.3	0.6	1.8	-0.4	0.2	1.4	0.7
Glucose	0.1	0.2	0.6	-0.8	-0.1	-0.0	-0.1
Heart weight	1.7	2.4	3.4	1.8	-1.5	-1.4	-1.4
Left kidney weight	0.5	1.4	2.0	-1.1	1.0	1.1	1.4
Right kidney weight	0.3	0.8	1.8	-0.5	0.3	1.3	1.1
Tail length	2.4	7.4	15.7	-4.0	2.7	0.1	2.6
Length with tail	1.7	6.1	15.0	-3.9	2.0	0.8	2.2
Length without tail	0.2	0.5	1.7	-0.4	-0.3	1.3	0.0
Liver weight, left	1.3	2.2	3.8	-0.6	1.5	2.0	1.5
Liver weight, right	0.9	1.5	2.8	-0.6	1.1	1.7	1.4
Parametrial fat weight	0.3	0.6	0.9	-0.9	0.7	0.7	0.8
Retroperitoneal fat weight	0.4	1.2	4.0	0.0	-0.5	2.0	0.7
Intraocular pressure	2.5	3.6	5.5	1.2	-2.3	-1.6	-2.2
Extensor digitorum longus weight	0.1	0.4	1.1	0.1	-0.6	1.1	-0.1
Soleus weight	0.1	0.2	0.6	0.5	-0.2	0.8	0.0
Tibialis anterior weight	0.2	0.6	0.9	-0.1	-1.0	-1.0	-0.6
Tibia length	0.3	0.7	2.4	-1.6	0.5	-0.5	0.1
Number of licking bursts	0.4	0.5	0.7	0.5	0.6	0.7	0.9
Food consumed during 24 hour testing period	6.5	7.8	10.9	-1.1	3.2	3.0	3.3
Times rat made contact with spout	0.0	0.0	0.1	0.3	0.2	0.1	0.0
Mean time between licks in bursts	0.2	0.3	0.8	0.9	-0.4	-0.6	-0.1
Mean num. licks in bursts	0.4	0.5	1.1	0.0	-0.4	-1.0	-0.9
Std. dev. time between licks in bursts	0.9	1.0	2.1	-0.6	1.2	0.6	1.4
Water consumed over 24 hours	1.2	1.4	2.1	0.2	1.5	1.4	1.3
Indifference point 0 sec	0.2	0.3	0.4	-0.6	-0.5	-0.7	0.2
Indifference point AUC	1.7	2.0	3.0	-1.0	1.7	1.3	1.5
Indifference point function ln k	2.4	3.4	5.0	1.1	-2.0	-2.2	-1.8
Indifference point function log k	2.4	3.4	5.0	1.1	-2.0	-2.2	-1.8
Delay discounting total patch changes 0 sec	0.2	0.3	0.7	-0.3	-0.9	-0.6	-0.2
Delay discounting total patch changes 12 sec	1.2	1.5	3.0	-1.1	1.1	0.8	1.7
Delay discounting total patch changes 18 sec	2.5	3.4	5.7	-0.9	2.3	1.3	2.4
Delay discounting total patch changes 24 sec	1.3	1.6	2.5	-1.4	1.3	0.5	1.6
Delay discounting total patch changes 6 sec	0.5	0.7	1.1	-0.5	0.9	0.8	1.1
Delay discounting time to switch 0 sec	0.2	0.2	0.4	0.0	0.4	0.6	0.6
Delay discounting water rate 0 sec	0.0	0.0	0.1	-0.0	-0.2	0.3	-0.2
Delay discounting water rate 12 sec	1.1	1.6	3.1	1.3	-0.5	-1.8	-1.2
Delay discounting water rate 18 sec	1.0	1.4	5.2	0.2	0.1	-2.3	-0.5
Delay discounting water rate 24 sec	0.9	1.3	3.8	0.2	-0.7	-2.0	-0.8
Delay discounting water rate 6 sec	2.0	2.9	5.9	-0.7	2.4	1.0	2.0
Locomotor activity	1.1	1.8	3.8	1.8	0.1	1.9	-0.0
Locomotor testing distance	1.3	2.2	4.5	2.1	0.3	2.1	0.0
Locomotor testing rearing	1.8	2.8	5.1	0.5	1.7	2.3	1.8
Light reinforcement 1	10.4	19.0	29.5	-3.3	5.0	3.4	5.4
Light reinforcement 2	10.6	14.0	18.3	-3.2	4.1	3.2	4.3
Reaction time number correct	1.3	1.9	2.6	0.7	-1.5	-1.6	-1.5
Reaction time mean minus median	0.6	0.8	1.1	-0.8	-1.1	-0.7	-1.0
Reaction time mean minus median AUC	1.1	1.4	2.5	-0.3	-1.6	-0.8	-1.5
Reaction time num false alarms	1.2	1.6	4.0	1.1	-2.0	-0.2	-1.1
Reaction time num false alarms AUC	1.3	1.8	3.4	1.4	-1.8	-0.7	-1.2
Reaction time trials correct on left	1.3	1.9	2.6	0.7	-1.5	-1.6	-1.5
Reaction time trials on left	1.4	2.0	2.6	0.7	-1.6	-1.5	-1.6
Reaction time mean	2.2	3.0	6.0	0.6	-2.5	-0.9	-2.2
Reaction time mean AUC	2.3	3.0	5.8	0.8	-2.4	-0.8	-2.2
Median of all reaction times	2.5	3.4	6.5	1.1	-2.6	-0.8	-2.3
Reaction time omissions	0.8	1.1	2.9	-0.3	-1.7	0.4	-1.1
Reaction time false alarm rate	0.3	0.4	0.7	0.8	-0.8	-0.0	-0.4
Reaction time premature initiation rate	4.7	6.4	10.0	-2.4	3.2	0.8	3.0
Reaction time premature initiations	1.9	2.7	4.1	-1.7	2.0	0.1	2.0
Std. dev. reaction times	0.7	0.9	1.6	-0.6	-1.3	-0.6	-1.2
Reaction time trials completed	1.4	2.0	2.6	0.7	-1.6	-1.5	-1.6
Reaction time trials AUC	1.4	2.0	2.8	0.8	-1.7	-1.4	-1.6
Social response proportion	0.5	0.5	1.0	0.3	-0.9	1.0	-0.2
Social responses	0.5	0.7	1.4	1.2	-0.1	1.1	0.4
Social time	0.2	0.3	0.5	-0.1	0.7	-0.6	0.3
Conditioned locomotion	0.1	0.1	0.2	-0.4	0.3	0.3	0.4
Cocaine response after cond. corrected	0.4	0.5	1.1	0.6	-0.7	1.0	-0.2
Cocaine response after cond. not corrected	0.6	0.7	1.9	0.6	-0.6	1.4	-0.1
Cocaine response before conditioning	0.2	0.2	0.5	-0.3	0.7	0.1	0.6
Saline control response	2.9	3.9	7.4	-0.6	1.6	2.7	2.3
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	-0.3	0.2	-0.5	0.3
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.1	-0.4	-0.3	-0.1	-0.3
Condit. Reinf. active responses	0.1	0.1	0.1	0.3	0.3	0.2	0.4
Condit. Reinf. inactive responses	0.4	0.5	1.3	1.2	-0.1	0.9	0.0
Condit. Reinf. lever presses	0.1	0.2	0.6	0.8	-0.2	0.1	-0.4
Condit. Reinf. lever reinforcers received	0.0	0.1	0.1	0.3	0.2	0.1	0.2
Pavlov. Cond. lever latency	0.1	0.2	0.5	-0.7	-0.5	0.0	-0.0
Pavlov. Cond. magazine entry latency	0.2	0.2	0.7	-0.9	0.0	0.1	0.2
Pavlov. Cond. change in total contacts	0.1	0.2	0.5	0.3	0.2	-0.7	-0.2
Pavlov. Cond. index score	0.0	0.0	0.1	-0.0	0.4	-0.2	-0.0
Pavlov. Cond. latency score	0.0	0.1	0.1	-0.1	0.4	-0.3	0.0
Pavlov. Cond. lever contacts	0.1	0.2	0.4	0.4	0.6	0.3	0.3
Pavlov. Cond. magazine entry number	0.1	0.2	0.6	0.8	-0.0	0.2	0.1
Pavlov. Cond. intertrial magazine entries	1.2	1.6	3.2	-0.2	1.5	0.9	1.8
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	0.1	0.2	-0.3	-0.2
Pavlov. Cond. response bias	0.0	0.0	0.1	0.2	0.2	0.2	-0.0
Conditioned reinforcement - actives	0.0	0.0	0.0	-0.2	-0.1	0.0	-0.2
Conditioned reinforcement - inactives	0.1	0.1	0.3	-0.3	-0.1	-0.6	-0.4
Conditioned locomotion	0.3	0.4	0.9	1.0	-0.2	-0.5	-0.5
Intermittent access intake day 1-15 change	2.0	2.0	3.6	-1.4	1.9	0.3	1.6
Intermittent access intake escalation	2.6	2.6	4.3	-1.6	2.1	0.6	1.7
Intermittent access intake escalation 2	2.1	2.0	3.9	-1.4	2.0	0.1	1.5
Intermitt. access day 1 inactive lever presses	0.6	0.6	2.2	0.4	0.1	-1.5	-0.3
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.4	0.6	-0.3	0.3	-0.6
Intermitt. access escalation Index	0.2	0.2	0.2	0.3	0.5	0.4	0.5
Intermittent access day 1 total infusions	1.2	1.4	2.0	1.2	-1.4	-0.4	-1.4
Intermittent access day 15 total infusions	0.1	0.1	0.2	-0.5	0.2	-0.2	-0.0
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.2	-0.2	-0.0	-0.4	-0.3
Intermittent access total infusions	0.1	0.2	0.3	0.2	-0.4	-0.3	-0.6
Intermittent access day 1 locomotion	2.0	2.0	4.4	2.1	-1.1	-0.8	-1.3
Intermittent access day 15 total locomotion	0.6	0.7	1.0	1.0	-0.7	0.7	-0.8
Intermittent access total locomotion	1.3	1.5	2.9	1.7	-1.2	0.4	-1.2
Intermittent access standard deviation	0.7	0.8	2.4	-0.5	0.6	-1.5	-0.1
Cocaine induced anxiety	0.1	0.2	0.3	-0.5	-0.2	-0.6	-0.3
Post-drug Anxiety	0.5	0.5	1.0	0.4	-0.9	-0.5	-1.0
Baseline Anxiety	0.5	0.5	1.8	0.1	-0.3	1.3	0.1
Lifetime Intake	0.1	0.1	0.2	-0.0	-0.3	-0.3	-0.5
Incentive Sensitization - Responses	0.2	0.2	0.6	-0.8	0.2	-0.4	0.0
Incentive Sensitization - Breakpoint	0.2	0.2	0.7	-0.8	0.2	-0.4	0.1
Progressive ratio test 1 active lever presses	1.3	1.3	2.2	1.0	-1.5	-0.2	-1.4
Progressive ratio test 1 breakpoint	1.1	1.1	1.8	0.8	-1.4	-0.3	-1.3
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.4	0.0	-0.3	-0.5	-0.6
Progressive ratio test 2 active lever presses	0.5	0.5	0.9	0.3	-0.9	-0.5	-1.0
Progressive ratio test 2 breakpoint	0.5	0.5	0.9	0.3	-1.0	-0.2	-1.0
Progressive ratio test 2 inactive lever presses	1.1	1.3	2.5	0.9	-1.3	-0.4	-1.6
Total sessions with >9 infusions	3.5	3.8	5.4	1.4	-1.8	-2.3	-2.2
Short access day 1 total inactive lever presses	0.5	0.6	1.5	-1.2	0.6	0.5	0.3
Short access day 10 total inactive lever presses	0.5	0.6	1.3	-0.3	1.1	-0.6	0.7
Short access day 1 total infusions	2.8	3.0	4.8	0.6	-1.8	-1.9	-2.2
Short access day 10 total infusions	0.1	0.1	0.2	0.5	-0.0	0.4	-0.2
Short access total infusions	0.1	0.2	0.3	-0.2	-0.4	-0.3	-0.6
Short access day 1 locomotion	1.8	1.9	3.0	0.7	-1.5	-1.3	-1.7
Short access day 10 total locomotion	2.8	3.1	8.1	2.8	-1.2	-0.9	-1.5
Short access total locomotion	3.5	3.6	5.7	2.4	-1.5	-1.6	-1.9
Compulsive drug intake	0.9	0.9	3.0	-0.2	0.6	-1.7	0.2
One hour access (0.3 mA shock)	0.0	0.0	0.1	-0.1	-0.1	-0.3	-0.2
One hour access (shock baseline)	0.5	0.5	0.9	0.6	-0.9	0.7	-0.7
Number of responses in last shaping day	2.4	2.4	3.7	0.7	-1.6	-1.7	-1.9
Context. condit. distance diff. score	0.8	1.0	2.7	0.4	-1.6	-0.3	-1.0
Locomotion velocity, session 1	0.9	0.9	2.1	-0.0	1.5	0.4	1.2
Locomotion distance, session 1	0.6	0.8	1.4	0.6	0.7	1.2	1.0
Locomotion velocity, session 2	0.6	0.7	1.0	-0.6	1.0	0.6	1.0
Locomotion distance, session 2	0.5	0.7	1.8	0.7	-0.0	1.3	0.6
Locomotion velocity, session 3	0.2	0.2	0.6	0.3	-0.2	-0.8	-0.4
Locomotion distance, session 3	0.6	0.6	2.0	-0.4	0.4	-1.4	0.4
Stereotopy head waving bouts, day 3	1.6	1.9	4.6	0.4	-0.9	-2.2	-1.4
Stereotopy head waving duration, day 3	0.8	1.0	1.3	0.9	-0.8	-1.1	-1.1
Locomotion velocity, session 7	0.3	0.3	0.5	0.4	-0.7	-0.6	-0.4
Locomotion distance, session 7	0.2	0.3	0.6	0.2	0.3	0.8	0.6
Stereotopy head waving bouts, day 7	0.7	0.8	2.5	-0.7	0.4	-1.6	0.2
Stereotopy head waving duration, day 7	0.5	0.7	1.6	-0.6	0.7	-1.3	0.4
Locomotion velocity, session 8	0.3	0.3	0.8	-0.9	-0.0	0.6	0.5
Locomotion distance, session 8	0.2	0.3	0.7	0.5	-0.7	0.8	0.2
Degree of sensitization distance	0.8	0.8	3.1	0.3	-0.2	1.8	0.1
Degree of sensitization stereotypy	0.4	0.4	1.5	-0.3	0.0	-1.2	-0.1
Condit. Reinf. active minus inactive responses	1.9	2.1	5.2	-0.3	-1.6	-2.3	-0.8
Condit. Reinf. active-inactive response ratio	0.9	1.0	2.6	-0.2	-1.6	-1.0	-0.7
Condit. Reinf. active responses	1.0	1.2	3.9	-0.6	-0.8	-2.0	-0.3
Condit. Reinf. inactive responses	1.4	1.6	3.0	-1.3	1.7	-0.2	1.4
Incentive salience index mean	1.2	1.5	5.0	-1.0	-0.2	-2.2	0.1
Condit. Reinf. lever presses	1.4	1.8	2.7	-1.6	1.2	-1.6	0.8
Time in familiar zone, hab. session 1	0.3	0.3	0.5	-0.6	0.5	-0.2	0.7
Time in novel zone, hab. session 1	1.5	1.4	3.2	1.8	-0.8	-0.1	-1.4
Total zone transitions, hab. session 1	0.6	0.8	1.8	-0.1	0.9	1.3	0.8
Total locomotion distance, hab. session 1	0.3	0.5	0.9	0.6	0.6	1.0	0.4
Locomotion velocity, hab. session 1	0.5	0.7	1.5	0.3	0.8	1.2	0.7
Time in familiar zone, hab. session 2	0.9	0.9	1.8	-0.6	1.2	0.4	1.3
Time in novel zone, hab. session 2	2.2	2.2	3.5	1.5	-1.9	0.1	-1.8
Total zone transitions, hab. session 2	0.8	1.0	1.5	0.6	1.2	0.9	1.2
Total locomotion distance, hab. session 2	0.6	0.8	1.5	0.5	0.8	1.2	0.9
Locomotion velocity, hab. session 2	0.6	0.9	1.6	0.2	0.9	1.3	1.0
Novel to familiar place preference ratio	0.9	1.0	2.5	1.6	-0.7	0.5	-0.8
Novelty place preference	1.0	1.1	2.7	1.6	-0.6	0.8	-0.7
Time in novel zone, NPP test	1.4	1.5	3.9	2.0	-0.8	0.4	-1.1
Total zone transitions, NPP test	1.0	1.4	2.6	-0.8	1.1	1.0	1.6
Total locomotion distance, NPP test	0.2	0.2	0.3	0.2	0.5	0.6	0.6
Locomotion velocity, NPP test	0.4	0.6	1.0	-0.5	0.5	0.8	1.0
Pavlov. Cond. lever latency	0.5	0.6	1.9	0.5	0.2	1.4	0.5
Pavlov. Cond. magazine entry latency	1.0	1.2	1.9	0.9	-0.9	-1.3	-1.4
Pavlov. Cond. change in total contacts	0.5	0.6	1.4	-0.8	0.4	-1.2	0.1
Pavlov. Cond. index score	0.9	1.1	2.7	0.3	-0.7	-1.7	-1.1
Pavlov. Cond. latency score	0.4	0.6	1.6	-0.1	-0.4	-1.3	-0.7
Pavlov. Cond. lever contacts	0.5	0.6	1.5	-0.4	-0.3	-1.2	-0.7
Pavlov. Cond. magazine entry number	1.7	2.1	4.2	-0.6	1.1	2.1	1.7
Pavlov. Cond. intertrial magazine entries	0.7	0.9	2.0	-1.4	-0.1	-1.2	0.4
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	2.9	0.4	-1.0	-1.7	-1.4
Pavlov. Cond. response bias	1.3	1.7	3.4	0.5	-0.8	-1.8	-1.5
Bone: apparent density	2.1	3.4	8.4	-0.7	2.9	0.8	2.1
Bone surface	1.7	3.0	6.0	-1.6	2.4	-0.5	1.7
Bone volume	2.0	3.4	7.1	-1.7	2.7	-0.2	1.9
Bone: connectivity density	2.9	4.6	11.1	-1.1	3.3	0.4	2.4
Bone: cortical apparent density	0.8	1.1	2.2	1.5	-0.7	-1.0	-0.8
Bone: cortical area	0.2	0.2	0.6	-0.5	0.2	0.3	0.8
Bone: cortical porosity	0.3	0.4	0.8	-0.6	-0.9	0.1	-0.6
Bone: cortical porosity	0.4	0.4	0.9	-1.0	-0.8	-0.3	-0.3
Bone: cortical thickness	0.7	1.2	2.7	1.2	-1.6	0.0	-0.8
Bone: cortical thickness	2.8	3.3	7.9	2.2	-0.2	2.8	0.3
Bone: cortical tissue density	0.7	1.0	1.9	1.4	-0.6	-1.0	-0.8
Bone: elastic displacement	1.1	1.3	1.9	0.9	-1.1	-1.4	-1.0
Bone: elastic work	1.6	2.0	3.0	1.7	-1.7	-0.6	-1.4
Bone: endosteal estimation	0.7	1.6	2.7	-0.7	1.2	1.6	1.4
Bone: endosteal perimeter	1.3	2.7	5.0	-2.2	1.4	0.4	1.9
Bone: final force	0.3	0.5	1.4	-0.5	0.3	1.2	0.6
Bone: final moment	0.2	0.4	1.2	-0.2	0.2	1.1	0.5
Bone: marrow area	0.7	1.6	2.8	-0.6	1.1	1.7	1.3
Bone: maximum diameter	0.4	0.7	2.1	-1.4	0.1	-0.7	0.6
Bone: maximum force	0.1	0.2	0.4	-0.5	0.1	0.6	0.4
Bone: maximum moment	0.1	0.1	0.3	-0.3	0.0	0.6	0.3
Bone: minimum diameter	1.5	2.7	4.2	-1.4	1.8	1.2	2.0
Bone: periosteal estimation	0.9	1.9	2.8	-0.9	1.3	1.5	1.7
Bone: periosteal perimeter	0.8	1.4	2.4	-1.5	0.8	0.2	1.5
Bone: post-yield work	1.0	1.3	1.9	-0.5	1.4	1.3	1.1
Bone: stiffness	0.8	1.3	2.3	-1.4	0.5	1.5	0.8
Bone: tissue strength	0.5	0.5	0.8	-0.4	-0.9	-0.8	-0.7
Bone: trabecular number	2.3	3.5	9.4	-1.1	3.1	-0.3	1.8
Bone: trabecular spacing	2.0	2.6	6.4	1.0	-2.5	-0.1	-1.7
Bone: trabecular thickness	0.6	0.7	1.8	-0.1	1.3	0.7	0.7
Bone: trabecular tissue density	1.0	1.4	2.3	0.9	-1.5	0.7	-1.3
Breakpoint value in progressive ratio session	2.0	2.2	8.3	0.5	-0.3	2.9	0.2
Distance traveled before self-admin	0.2	0.2	0.4	-0.1	-0.5	0.1	-0.7
Distance traveled after self-admin	0.2	0.2	0.8	-0.1	-0.2	-0.3	-0.9
Delta time in closed arm before/after self-admin	1.0	1.0	2.0	0.3	-1.4	-0.9	-1.0
Delta time in open arm before/after self-admin	4.2	4.0	6.9	-1.1	1.8	2.6	2.2
Diff in mean of infusions in LGA sessions	0.3	0.3	0.8	0.1	0.3	0.9	0.6
Extinction: sum of active levers before priming	3.4	3.4	5.3	2.3	-2.0	-1.2	-1.7
Active lever presses in extinction session 6	0.7	0.7	2.3	0.2	-0.1	-1.5	-0.6
Delta distance traveled before/after self-admin	0.1	0.1	0.2	0.4	-0.1	-0.4	-0.3
Delta ambulatory time before/after self-admin	0.2	0.2	0.4	0.1	0.7	-0.5	0.3
Time in closed arm before self-admin	0.4	0.4	0.9	0.2	0.9	-0.8	0.2
Time in closed arm after self-admin	0.2	0.2	0.4	-0.5	-0.4	-0.6	-0.2
Time in open arm before self-admin	0.9	1.0	1.8	0.2	-1.3	-0.9	-1.1
Time in open arm after self-admin	0.3	0.3	0.6	0.5	-0.4	0.8	-0.1
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.7	0.1	0.5	0.8	0.8
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.6	-0.5	0.7	0.5	0.7
Time to tail flick, vehicle, after self-admin	3.2	3.4	4.9	-2.1	0.9	2.2	1.9
Time to tail flick, test, before self-admin	0.6	0.6	1.2	-0.2	-1.1	0.1	-1.0
Time to tail flick, test, after self-admin	0.4	0.4	0.8	-0.9	0.3	0.7	0.6
Delta time to tail flick, vehicle, before/after SA	1.5	1.5	3.6	-1.9	0.5	0.9	1.1
Delta time to tail flick, test, before/after SA	0.0	0.0	0.1	-0.2	0.2	-0.1	0.3
Ambulatory time before self-admin	0.4	0.4	0.8	0.2	-0.8	0.3	-0.9
Ambulatory time after self-admin	0.1	0.1	0.2	-0.4	0.5	0.2	-0.2
Total heroin consumption	0.5	0.6	1.3	1.1	-0.3	1.1	0.0
Area under the delay curve	0.2	0.2	0.4	0.3	-0.5	-0.6	-0.3
Delay disc. indifference point, 0s delay	0.4	0.4	0.8	-0.4	0.9	-0.2	0.7
Delay disc. indifference point, 16s delay	0.7	0.7	1.1	1.0	-1.1	0.5	-0.7
Delay disc. indifference point, 2s delay	0.6	0.7	1.0	0.5	-0.9	-0.8	-1.0
Delay disc. indifference point, 24s delay	0.6	0.6	1.5	-0.3	-1.2	-0.7	-0.6
Delay disc. indifference point, 4s delay	0.3	0.3	0.7	0.2	0.9	-0.6	0.4
Delay disc. indifference point, 8s delay	0.5	0.6	0.9	0.5	-1.0	-0.9	-0.5
Delay discount exponential model param	0.2	0.2	0.5	-0.3	0.5	0.7	0.3
Delay discount hyperbolic model param	0.2	0.2	0.6	-0.3	0.5	0.8	0.3
Fecal boli incidents, locomotor time 1	3.1	3.4	7.3	-2.7	1.7	0.3	1.8
Change in fecal boli incidents, locomotor task	0.5	0.5	1.1	0.8	0.4	-1.0	0.1
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.5	0.1	0.7	0.5	0.3
Bouts of movement, locomotor time 1	0.3	0.4	1.2	-0.4	-0.1	-1.1	-0.4
Total resting periods, locomotor time 1	0.7	0.8	2.4	-0.3	-0.4	-1.5	-0.7
Rest time, locomotor task time 1	0.8	0.9	2.4	-0.5	-0.6	-1.5	-0.8
Distance moved, locomotor task time 1	0.7	0.8	2.0	1.0	-0.1	1.4	-0.0
Vertical activity count, locomotor time 1	4.5	4.7	7.6	-1.6	1.9	2.8	2.2
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.0	0.3	-0.8	0.0	-1.0
Bouts of movement, locomotor time 2	0.7	0.8	1.1	1.1	-0.8	-0.6	-1.0
Total resting periods, locomotor time 2	0.2	0.2	0.3	0.6	-0.4	-0.2	-0.6
Rest time, locomotor task time 2	0.4	0.5	0.7	-0.7	0.9	0.3	0.7
Distance moved, locomotor task time 2	1.5	1.8	2.9	1.2	-1.7	-0.1	-1.6
Vertical activity count, locomotor time 2	0.9	1.0	2.0	-0.9	0.5	1.4	1.0
Weight adjusted by age	0.3	0.4	1.0	-0.1	-1.0	-0.1	-0.6
Seeking ratio, delayed vs. immediate footshock	2.1	2.4	4.9	2.2	-1.5	-0.6	-1.4
Locomotion in novel chamber	1.2	1.5	3.9	1.3	-0.7	2.0	0.0
Locomotion in novel chamber post-restriction	0.6	0.7	2.3	1.5	0.5	-0.2	-0.2
Progressive ratio	0.8	1.0	1.9	-0.4	0.8	1.4	1.1
Food seeking constrained by brief footshock	1.8	2.2	3.1	-1.6	1.8	0.5	1.7
Seeking ratio, punishment vs. effort	0.3	0.4	0.7	-0.8	0.5	-0.9	0.2
Run reversals in cocaine runway, females	1.1	1.1	2.2	-0.1	-1.5	1.2	-0.8
Run reversals in cocaine runway, males	0.2	0.2	0.5	0.5	-0.2	-0.2	-0.7
Latency to leave start box in cocaine runway	0.5	0.6	2.1	-0.2	-0.3	1.4	0.2
Latency to leave start box in cocaine runway, F	0.4	0.4	0.6	0.5	-0.7	0.7	-0.6
Latency to leave start box in cocaine runway, M	2.9	2.8	3.7	-1.6	1.2	1.9	1.9
Cd content in liver	0.2	0.2	0.6	0.0	-0.3	-0.8	0.2
Co content in liver	2.8	3.3	6.6	0.7	-1.8	-2.6	-1.7
Cu content in liver	0.3	0.3	0.9	0.1	-0.9	-0.3	-0.5
Fe content in liver	0.9	1.1	2.5	-1.3	0.1	-1.6	-0.4
K content in liver	0.5	0.5	1.4	1.2	-0.5	0.0	-0.6
Mg content in liver	0.9	0.9	1.4	1.2	-0.8	-0.9	-1.0
Mn content in liver	0.0	0.0	0.1	-0.1	-0.1	0.3	0.2
Na content in liver	0.2	0.2	0.7	-0.1	0.4	0.8	0.2
Rb content in liver	0.1	0.1	0.2	-0.3	0.2	-0.4	0.1
Se content in liver	1.5	1.8	5.0	-2.2	0.9	-1.0	0.7
Sr content in liver	0.5	0.4	0.8	0.8	-0.9	-0.1	-0.5
Zn content in liver	0.3	0.4	0.7	0.8	-0.8	0.3	-0.3